This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Dyslexia and other symbolic dysfunctions, not elsewhere classified
R18_DYSLE_OTHER_SYMBO_DYSFU_NOT_ELSEW_CLASSIFIED
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
162 |
4. Check minimum number of eventsNone |
162 |
5. Include endpointsNone |
162 |
6. Filter based on genotype QC (FinnGen only) |
146 |
Control definitions (FinnGen only)
- Control exclude
- R18_SYMPTOMS_SIGNS_INVOLVI_SPEECH_VOICE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R4[7-9]
- Name in latin
- Dyslexia et aliae dysfunctiones discretionis symbolorum non alibi classificatae
Similar endpoints
↥List of similar endpoints to
Dyslexia and other symbolic dysfunctions, not elsewhere classified
based on the number of shared cases.
Similar with more cases:
- Symptoms and signs involving speech and voice
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any operation in hilmo
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 146 | 81 | 65 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | 55.48 | 51.44 | 60.51 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 149
- Matched controls
- 1490
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R48.0
ICD-10 Finland
Dyslexia and alexia
+∞
78.2
68
*
R48.2
ICD-10 Finland
Apraxia
+∞
37.0
34
*
R48.8
ICD-10 Finland
Other and unspecified symbolic dysfunctions
+∞
25.8
24
*
R48
ICD-10 Finland
Dyslexia and other symbolic dysfunctions, not elsewhere classified
+∞
15.9
15
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.8
13.0
26
52
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
5.1
12.1
29
68
R47.0
ICD-10 Finland
Dysphasia and aphasia
+∞
11.6
11
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.8
11.0
28
69
R48.1
ICD-10 Finland
Agnosia
+∞
10.5
10
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
4.1
10.5
33
96
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
4.5
9.9
27
70
R53
ICD-10 Finland
Malaise and fatigue
3.0
9.7
61
276
Z2445
NOMESCO Finland
Psychologist
9.1
8.9
18
22
AA1AD
NOMESCO Finland
CT of head and brain
2.8
8.2
55
254
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
4.0
7.9
25
72
N06AB10
ATC
escitalopram; oral
2.9
7.6
44
187
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
6.4
7.5
19
33
R50.9
ICD-10 Finland
Fever, unspecified
3.1
7.4
36
138
N03AX12
ATC
[U] gabapentin; oral
3.2
7.3
33
121
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.4
7.3
30
104
R4120
NOMESCO Finland
Occupational therapy
4.6
7.2
18
43
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
4.4
7.1
19
48
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
6.3
6.7
17
30
Z01.8
ICD-10 Finland
Other specified special examinations
2.7
6.2
41
185
R51.80
ICD-10 Finland
Headache
2.7
6.0
38
167
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
47
278
2.01
3.59
1.3
1.3
2.59
1.23
u/ml
0.53
16
65
6
6
10.35
3.53
1.2
1.5
1.98
1.86
mmol/l
—
6
6
34
183
2.11
3.32
3.1
3.0
2.61
2.12
e6/l
0.14
17
99
9
19
4.97
3.29
1.7
1.9
—
—
—
0
0
47
293
1.88
3.02
5.3
3.9
1.02
1.02
kg/l
0.31
37
192
62
424
1.79
2.95
4.1
3.3
—
—
—
0
0
53
347
1.82
2.90
3.5
3.2
0.31
0.28
e6/l
0.05
41
255
74
537
1.75
2.85
2.3
2.0
84.42
93.36
pmol/l
1.16
41
281
6
10
6.20
2.72
1.0
1.2
—
—
—
0
0
78
584
1.70
2.62
7.6
8.0
1.21
1.22
mmol/l
0.31
72
499
6
11
5.63
2.57
1.0
1.2
—
—
—
0
0
32
187
1.91
2.47
1.6
1.7
830.88
1162.65
nmol/l
2.19
26
146
6
12
5.16
2.42
1.0
1.2
—
—
—
0
0
6
12
5.16
2.42
1.3
1.3
—
—
—
0
0
38
241
1.77
2.26
3.3
3.4
27.17
360.97
ng/l
1.50
23
178
125
1089
1.92
2.25
7.1
5.2
2.11
1.90
mu/l
0.24
117
990
87
689
1.63
2.22
9.9
10.6
4.41
4.20
e9/l
0.30
81
610
108
908
1.69
2.13
5.5
4.3
14.54
14.75
pmol/l
0.39
98
813
15
69
2.31
2.13
1.1
1.0
—
—
—
0
0
84
665
1.60
2.10
5.0
4.0
0.16
0.00
estimate
0.48
19
127
19
98
2.08
2.06
4.1
4.1
2.62
1.98
mmol/l
0.74
19
84
6
15
4.12
2.06
2.7
3.5
1.24
1.21
mmol/l
—
6
15
51
363
1.62
1.96
4.9
3.9
0.00
0.02
estimate
0.74
19
121
6
16
3.86
1.95
2.7
3.4
110.17
105.31
mmol/l
—
6
16
16
79
2.15
1.94
2.1
3.9
155.35
67.38
ng/l
0.94
16
69
82
661
1.53
1.80
5.1
3.9
0.00
12.12
estimate
0.50
20
134
81
654
1.52
1.74
5.0
3.9
0.00
0.00
estimate
-0.00
20
133
30
192
1.70
1.71
2.9
2.9
0.64
0.92
e6/l
0.35
13
107
13
62
2.20
1.71
4.5
4.4
136.31
128.71
g/l
0.92
13
62
10
43
2.42
1.62
4.2
4.3
26.10
25.12
mmol/l
—
10
43
16
89
1.89
1.44
1.4
1.2
40.00
157.72
u/ml
—
8
33
15
82
1.92
1.41
2.5
2.3
2.59
4.71
ug/l
1.12
15
69
11
54
2.12
1.36
4.3
2.9
0.55
0.62
%
0.45
11
54
72
590
1.43
1.32
3.3
3.1
94.81
106.65
ug/l
0.31
67
545
11
55
2.08
1.31
6.3
3.8
37.59
45.14
%
0.41
11
55
38
276
1.51
1.30
2.0
2.3
—
—
—
0
0
46
350
1.45
1.25
1.8
1.7
20.72
22.41
nmol/l
0.33
39
287
128
1178
1.61
1.21
21.6
15.5
18.83
22.90
mg/l
1.14
112
971
48
370
1.44
1.21
4.4
3.5
0.00
0.00
estimate
-0.00
16
102
77
646
1.40
1.21
6.5
6.4
12.42
10.98
umol/l
0.33
69
613
62
502
1.40
1.19
5.2
3.9
0.06
0.03
estimate
0.22
16
111
67
558
1.36
1.06
2.6
2.9
—
—
estimate
—
0
0
5
22
2.32
1.04
1.2
1.3
—
—
—
0
0
5
22
2.32
1.04
1.2
1.3
—
—
—
0
0
12
68
1.83
1.04
3.8
2.7
171.50
132.90
ng/l
0.24
12
62
26
184
1.50
1.00
2.3
3.2
0.84
0.83
mmol/l
0.34
26
175
10
54
1.91
0.99
4.6
2.9
1.95
1.09
%
—
10
54
5
23
2.21
0.99
9.8
2.9
7.94
8.98
pmol/l
—
5
23
92
813
1.34
0.96
3.8
3.3
41.61
42.31
u/l
0.05
87
767
31
231
1.43
0.93
1.6
1.8
413.85
431.98
pmol/l
0.15
26
198
33
253
1.39
0.85
1.8
1.6
—
—
—
0
0
6
32
1.91
0.82
1.2
1.3
—
1.04
—
0
5
28
211
1.40
0.80
1.5
1.4
24.37
7.79
u/ml
0.31
12
77
55
462
1.30
0.78
5.5
3.9
72.87
37.28
ng/l
0.42
45
311
34
268
1.35
0.74
1.5
1.7
2.49
1.42
mg/l
0.37
28
214
5
25
2.03
0.73
1.4
1.3
—
—
—
0
0
5
26
1.95
0.71
1.2
1.2
—
—
—
0
0
43
513
0.77
0.70
2.0
2.0
1.33
1.36
mmol/l
0.14
37
425
30
235
1.35
0.68
1.6
1.3
13.52
29.15
iu/ml
—
6
75
39
326
1.27
0.57
2.3
2.0
2.27
2.79
mg/l
1.53
29
284
14
99
1.46
0.56
1.6
1.5
—
—
—
0
0
12
82
1.50
0.56
1.9
1.3
—
—
—
0
0
6
40
1.52
0.52
1.2
1.3
—
—
—
0
0
6
40
1.52
0.52
1.3
2.0
—
—
—
0
0
22
174
1.31
0.48
3.0
2.2
—
—
—
0
0
5
31
1.63
0.43
1.4
1.8
149.40
239.08
pmol/l
—
5
26
15
114
1.35
0.42
7.8
7.1
—
—
—
0
0
20
162
1.27
0.38
2.6
2.0
—
—
—
0
0
117
1120
1.21
0.38
5.8
4.9
5.99
5.91
mmol/l
0.19
108
1026
84
783
1.17
0.38
3.3
3.3
—
—
—
0
0
6
45
1.35
0.34
1.5
1.6
—
—
—
0
0
114
1093
1.18
0.34
4.7
4.0
1.27
1.26
mmol/l
0.09
106
998
116
1117
1.17
0.30
20.9
14.9
83.54
82.71
ml/min/173m2
0.14
107
1021
11
85
1.32
0.29
7.9
3.8
47.00
64.08
ml/min/173m2
—
6
37
20
169
1.21
0.27
2.3
1.6
—
—
—
0
0
5
72
0.68
0.26
1.4
1.5
—
—
—
0
0
9
75
1.21
0.25
2.1
1.2
—
—
—
0
0
5
39
1.29
0.23
1.6
1.3
—
9.62
—
0
11
5
40
1.26
0.22
1.2
1.5
—
—
—
0
0
5
40
1.26
0.22
1.2
1.3
—
—
—
0
0
19
164
1.18
0.21
2.3
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
4.0
—
1.10
—
0
10
0
12
0.00
0.21
0.0
1.0
—
15.03
—
0
6
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
18
207
0.85
0.20
1.3
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
960.31
—
0
14
0
14
0.00
0.20
0.0
4.3
—
525.21
—
0
14
6
52
1.16
0.19
1.0
2.2
34.80
40.12
u/l
—
6
44
120
1175
1.11
0.15
6.0
5.5
2.61
2.67
mmol/l
0.26
115
1083
24
220
1.11
0.12
2.3
1.8
—
—
—
0
0
118
1159
1.09
0.11
5.6
4.8
4.47
4.58
mmol/l
0.51
111
1072
5
47
1.07
0.09
1.6
3.3
6.60
112.02
u/ml
—
5
41
126
1243
1.09
0.09
13.9
11.3
24.76
25.04
u/l
0.08
121
1205
9
101
0.88
0.06
4.3
1.7
—
—
—
0
0
117
1158
1.05
0.04
5.3
4.7
1.42
1.46
mmol/l
0.50
111
1065
11
119
0.92
0.04
5.4
3.3
—
—
—
0
0
24
249
0.96
0.03
5.8
4.3
23.19
20.90
%
0.37
13
116
37
376
0.98
0.00
5.0
3.8
7.18
10.30
mg/mmol
0.25
27
234
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
98.40
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
13.22
—
0
9
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
8
83
0.96
-0.00
4.8
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.9
—
—
—
0
0
6
64
0.93
-0.00
1.3
3.3
855.83
70.78
u/ml
—
6
64
0
7
0.00
-0.00
0.0
1.3
—
15.74
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
1698.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
113.00
—
0
5
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
-0.00
0.0
1.0
—
149.60
—
0
5
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
6
0.00
-0.00
0.0
1.0
—
127.50
—
0
6
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
12.67
—
0
6
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
6.48
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
52
0.96
-0.00
1.4
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_DYSLE_OTHER_SYMBO_DYSFU_NOT_ELSEW_CLASSIFIED – Dyslexia and other symbolic dysfunctions, not elsewhere classified
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).