cervical carcinoma: A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma.
Other benign neoplasm of uterus: Cervix uteri
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_CERVIX_UTERI
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly females |
313377 |
2. Check conditionsNone |
313377 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
270 |
4. Check minimum number of eventsNone |
270 |
5. Include endpointsNone |
270 |
6. Filter based on genotype QC (FinnGen only) |
237 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D26
- Name in latin
- Neoplasma benignum cervicis uteri
Similar endpoints
↥List of similar endpoints to
Other benign neoplasm of uterus: Cervix uteri
based on the number of shared cases.
Similar with more cases:
- Other benign neoplasms of uterus
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1668 | 1668 | - |
| Only index persons | 1538 | 1538 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.05 | - |
| Only index persons | 0.06 | 0.06 | - |
| Median age at first event (years) | |||
| Whole population | - | 47.87 | - |
| Only index persons | - | 47.37 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 237 | 237 | - |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | - |
| Median age at first event (years) | 47.92 | 47.92 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 247
- Matched controls
- 2470
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D26.0
ICD-10 Finland
Other benign neoplasm: Cervix uteri
+∞
249.1
195
*
2190A
ICD-9 Finland
Other benign neoplasm of uterus, Cervix uteri
+∞
54.2
50
*
N84.1
ICD-10 Finland
Polyp of cervix uteri
11.5
32.6
36
36
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
27.9
26.6
36
15
8113
FHL
Fractional scraping
4.5
15.0
40
101
LCA06
NOMESCO Finland
Biopsy of endometrium
3.1
14.2
75
301
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.7
9.6
60
259
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
3.4
8.0
31
101
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
41.2
6.8
8
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.3
6.7
57
282
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.0
6.5
117
770
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
36
151
2.62
5.97
1.6
1.9
—
—
—
0
0
38
184
2.26
4.61
1.9
1.9
—
—
—
0
0
29
129
2.41
4.26
1.5
1.6
—
—
—
0
0
43
228
2.07
4.16
2.4
3.1
20.08
51.79
u/ml
1.07
43
217
86
635
1.54
2.59
1.4
1.5
—
—
—
0
0
149
1245
1.50
2.44
4.4
3.9
0.00
0.00
estimate
-0.00
31
254
151
1266
1.50
2.42
4.4
4.0
0.09
0.00
estimate
0.49
33
242
150
1258
1.49
2.39
4.4
3.9
0.00
6.29
estimate
0.50
34
258
10
37
2.77
2.09
1.2
1.6
—
—
—
0
0
5
10
5.08
2.08
2.6
2.6
—
—
—
0
0
193
1727
1.54
2.07
8.6
7.9
81.80
76.10
u/l
0.53
184
1621
145
1229
1.44
2.05
6.3
6.0
9.96
9.72
umol/l
0.15
137
1161
118
979
1.39
1.81
5.7
4.2
36.14
36.43
g/l
0.27
113
919
14
68
2.12
1.74
1.7
1.8
—
—
—
0
0
8
33
2.47
1.55
1.3
1.7
—
—
—
0
0
14
72
2.00
1.52
1.3
1.3
—
—
—
0
0
71
558
1.38
1.45
4.1
3.9
1.01
1.02
kg/l
0.92
49
366
59
452
1.40
1.40
1.7
1.7
428571889.55
35561952.88
pmol/l
0.64
49
374
7
29
2.45
1.40
2.9
1.5
—
—
—
0
0
9
41
2.24
1.38
4.6
3.7
14.67
57.19
u/ml
—
9
41
170
1536
1.34
1.33
3.6
3.2
49.23
39.06
u/l
0.80
160
1449
5
19
2.66
1.22
1.4
2.0
—
—
—
0
0
27
183
1.53
1.19
1.3
1.5
—
—
—
0
0
5
20
2.53
1.15
1.2
1.6
—
—
—
0
0
14
80
1.80
1.15
1.5
1.3
—
—
—
0
0
233
2240
1.71
1.14
17.8
15.7
139.56
139.76
mmol/l
0.63
227
2193
33
237
1.45
1.12
2.1
1.7
—
—
—
0
0
15
89
1.73
1.10
1.5
1.7
344.80
308.52
mu/l
0.27
15
80
7
32
2.22
1.09
1.0
1.6
—
—
—
0
0
227
2173
1.55
1.08
6.7
6.1
1.94
1.84
mu/l
0.60
214
2035
31
222
1.45
1.07
2.1
1.8
—
—
—
0
0
136
1213
1.27
1.07
3.5
3.3
79.26
81.03
ug/l
0.07
129
1140
82
689
1.28
1.04
2.3
2.1
97.80
139.18
u/l
1.97
74
655
5
22
2.30
1.04
1.0
1.0
—
—
—
0
0
204
1920
1.36
1.03
5.6
5.0
14.68
14.63
pmol/l
0.11
191
1787
9
50
1.83
0.97
1.1
1.5
—
—
—
0
0
14
85
1.69
0.96
3.4
2.7
23.86
25.16
mmol/l
0.95
14
85
108
946
1.25
0.96
4.3
3.7
0.11
0.00
estimate
0.69
27
208
43
335
1.34
0.93
3.0
2.8
4.64
3.98
e6/l
0.12
24
145
9
52
1.76
0.93
1.3
1.7
—
—
—
0
0
130
1168
1.24
0.91
7.0
5.9
1.23
1.22
mmol/l
0.42
112
996
84
719
1.26
0.90
3.6
3.8
3.53
6.33
mg/mmol
0.60
48
390
97
845
1.24
0.89
4.3
3.2
2.37
2.36
mmol/l
0.27
91
777
30
222
1.40
0.89
2.6
4.1
4.56
7.73
ug/l
0.51
24
178
140
1272
1.23
0.86
4.7
4.2
6.52
6.45
mmol/l
0.17
129
1184
239
2330
1.79
0.86
21.0
18.1
68.73
68.65
umol/l
0.03
234
2297
199
1883
1.29
0.84
21.6
18.3
332.17
330.84
g/l
1.25
199
1878
12
73
1.68
0.83
1.2
1.1
—
5.63
—
0
14
6
32
1.90
0.82
1.2
1.4
—
—
—
0
0
67
565
1.26
0.82
1.8
1.7
1.02
1.02
mg/l
0.00
53
437
27
200
1.39
0.80
1.2
1.3
22.29
28.00
iu/l
0.44
27
172
0
25
0.00
0.79
0.0
1.5
—
—
—
0
0
16
107
1.53
0.78
2.3
1.8
723.29
1137.79
u/l
—
7
35
13
194
0.65
0.74
2.2
2.4
65.67
68.73
ml/min/173m2
—
6
79
21
151
1.43
0.74
1.8
1.5
—
—
—
0
0
5
25
2.02
0.73
1.8
2.3
1.18
1.18
mmol/l
—
5
25
5
25
2.02
0.73
1.8
2.3
104.60
106.28
mmol/l
—
5
25
41
330
1.29
0.73
2.1
1.9
—
—
—
0
0
141
1520
0.83
0.71
3.9
3.4
—
—
—
0
0
223
2155
1.36
0.69
5.6
4.9
5.80
5.79
mmol/l
0.04
207
1995
125
1140
1.20
0.69
2.4
2.5
79.68
79.49
nmol/l
0.02
114
1037
237
2315
1.59
0.68
13.4
11.9
23.84
23.59
u/l
0.11
229
2247
5
29
1.74
0.64
1.4
1.2
0.14
0.18
nmol/l
—
5
17
6
104
0.57
0.63
1.2
2.7
30.50
41.29
u/l
—
6
95
42
346
1.26
0.63
1.6
1.7
1252.61
1208.40
nmol/l
0.10
33
251
5
30
1.68
0.61
1.0
1.5
—
—
—
0
0
230
2240
1.39
0.60
18.1
15.8
3.95
3.93
mmol/l
0.94
223
2186
15
106
1.44
0.59
1.6
1.4
—
—
—
0
0
6
35
1.73
0.58
1.2
2.1
—
—
—
0
0
8
55
1.47
0.56
2.4
2.3
—
—
—
0
0
47
549
0.82
0.55
2.0
2.2
—
—
—
0
0
9
62
1.47
0.53
1.8
2.4
24.19
24.86
mmol/l
—
9
62
9
62
1.47
0.53
1.1
1.6
—
—
—
0
0
9
136
0.65
0.53
1.9
1.3
—
—
—
0
0
114
1050
1.16
0.52
5.3
5.5
1.22
1.22
mmol/l
0.03
105
963
6
40
1.51
0.52
1.5
1.0
—
2.52
—
0
11
63
554
1.18
0.51
2.3
2.7
299.19
310.13
umol/l
0.47
58
487
215
2085
1.24
0.50
6.9
6.0
38.30
38.41
mmol/mol
0.08
205
1965
7
46
1.54
0.48
1.4
1.6
—
—
—
0
0
24
191
1.28
0.48
3.2
2.9
1.01
1.78
mmol/l
0.48
18
172
229
2239
1.31
0.47
5.7
5.7
2.75
2.81
mmol/l
0.46
218
2084
5
81
0.61
0.46
1.0
1.1
0.81
0.88
g/l
—
5
81
5
82
0.60
0.46
1.4
1.2
—
—
—
0
0
7
50
1.41
0.45
1.4
1.3
—
—
—
0
0
76
687
1.15
0.44
3.4
4.0
0.00
0.00
estimate
-0.00
31
243
226
2210
1.27
0.43
5.0
4.9
1.59
1.59
mmol/l
0.05
217
2049
8
57
1.42
0.42
1.6
1.7
—
—
—
0
0
14
105
1.35
0.42
4.8
3.1
45.01
47.96
%
0.14
14
105
226
2211
1.26
0.41
17.5
14.1
23.55
19.36
mg/l
1.00
184
1783
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
9
69
1.32
0.37
1.8
1.2
—
—
—
0
0
5
37
1.36
0.37
2.2
1.2
—
183.80
—
0
13
109
1020
1.12
0.37
2.2
2.1
108.02
99.61
pmol/l
0.96
60
486
35
302
1.19
0.36
1.5
2.1
—
—
—
0
0
5
77
0.64
0.36
1.0
1.1
1.61
1.64
g/l
—
5
77
5
78
0.63
0.36
1.6
1.2
—
—
—
0
0
5
79
0.63
0.36
1.6
1.2
—
—
—
0
0
17
136
1.27
0.34
2.9
2.5
130.47
178.97
ng/l
0.44
17
123
24
201
1.21
0.34
1.9
3.2
—
—
—
0
0
226
2218
1.22
0.34
5.1
5.0
4.76
4.82
mmol/l
0.42
218
2067
9
117
0.76
0.28
7.4
5.2
24.81
24.78
mmol/l
—
9
117
74
689
1.11
0.27
4.0
3.3
0.00
0.00
estimate
0.50
25
202
65
602
1.11
0.26
2.8
3.1
856.82
776.42
ng/l
0.17
56
507
56
516
1.11
0.25
1.4
1.3
1.02
9.59
u/ml
3.44
22
198
82
771
1.10
0.24
3.2
3.0
—
—
—
0
0
29
256
1.15
0.24
4.3
5.1
106.21
103.89
mmol/l
1.81
29
256
28
248
1.15
0.23
4.8
5.0
—
—
—
0
0
31
277
1.14
0.22
1.5
2.0
—
—
—
0
0
5
42
1.19
0.21
1.2
1.6
59.21
44.73
ug/l
—
5
42
5
42
1.19
0.21
1.2
1.2
—
—
—
0
0
5
42
1.19
0.21
1.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
4.8
—
472.45
—
0
11
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
3.0
—
4.45
—
0
10
0
10
0.00
0.21
0.0
3.0
—
11.46
—
0
10
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
7.75
—
0
12
30
269
1.13
0.21
1.7
1.9
3.11
3.22
ratio
0.28
19
220
138
1334
1.08
0.21
9.0
9.5
3.91
3.91
e9/l
0.01
122
1169
9
111
0.80
0.20
7.7
6.9
1.08
0.64
%
—
9
111
9
115
0.77
0.20
8.0
6.8
1.49
1.23
%
—
9
115
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
45
416
1.10
0.19
3.6
3.6
221.55
161.19
ng/l
0.15
29
286
7
59
1.19
0.18
1.1
1.2
3.46
3.77
mmol/l
—
7
51
112
1081
1.07
0.17
2.9
2.6
—
—
estimate
—
0
0
58
612
0.93
0.15
3.4
2.9
0.46
0.42
e6/l
0.11
38
425
104
1006
1.06
0.14
2.1
1.9
1.33
1.32
mmol/l
0.07
92
851
24
218
1.11
0.14
1.2
1.2
164.78
155.31
u/ml
0.05
12
99
23
209
1.11
0.13
1.7
1.8
3.75
3.41
mmol/l
0.91
12
159
207
2094
0.93
0.12
4.3
4.1
1.25
1.22
mmol/l
0.23
193
1927
213
2150
0.93
0.10
14.1
13.8
81.87
83.02
ml/min/173m2
0.40
196
1975
10
114
0.87
0.09
2.5
1.6
—
—
—
0
0
61
588
1.05
0.09
3.1
2.2
2.88
3.00
mg/l
0.18
53
505
5
61
0.82
0.08
1.2
1.2
—
—
—
0
0
7
64
1.10
0.08
2.0
1.6
0.65
5.56
ug/l
—
7
59
7
65
1.08
0.08
1.1
1.2
499.43
400.17
mg/l
—
7
59
82
799
1.04
0.08
3.7
3.6
150.42
102.71
ng/l
0.13
51
521
6
75
0.80
0.07
1.8
1.8
—
—
—
0
0
65
668
0.96
0.06
1.2
1.3
0.50
2.05
u/ml
1.50
22
188
57
553
1.04
0.06
1.4
1.3
16.04
34.64
iu/ml
2.16
14
178
11
100
1.10
0.05
1.4
1.7
—
—
—
0
0
13
120
1.09
0.05
2.4
2.9
23.88
24.22
mmol/l
0.15
13
120
192
1906
1.03
0.04
21.5
17.6
13.63
13.56
%
0.33
192
1893
26
270
0.96
0.03
5.4
4.6
34.07
34.30
%
0.03
15
168
68
669
1.02
0.03
1.8
1.6
21.12
21.80
nmol/l
0.16
61
566
174
1746
0.99
0.00
5.1
4.5
11.39
11.13
mm/h
0.11
161
1628
12
118
1.02
0.00
2.1
2.3
1.13
1.10
%
0.05
12
118
15
148
1.01
0.00
1.0
1.0
—
—
—
0
0
37
372
0.99
0.00
3.5
2.7
1.74
0.93
e6/l
0.50
20
182
12
121
0.99
0.00
1.3
1.4
—
—
—
0
0
55
549
1.00
0.00
2.2
1.6
—
—
—
0
0
12
117
1.03
0.00
2.1
2.2
0.75
0.58
%
0.58
12
117
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
4.7
—
44.68
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
0.22
—
0
8
5
56
0.89
-0.00
1.6
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
9.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
79
1.01
-0.00
2.1
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
59.52
—
0
9
6
65
0.92
-0.00
1.3
5.8
26.45
27.95
mg/l
—
6
58
5
57
0.87
-0.00
2.0
1.7
72.40
140.64
ug/l
—
5
52
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
-0.00
1.7
1.2
—
—
—
0
0
7
70
1.00
-0.00
1.9
1.1
—
66.81
—
0
11
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
6
65
0.92
-0.00
1.3
5.8
73.08
36.94
mg/l
—
6
58
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_CERVIX_UTERI and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CERVIX_UTERI | 1.246 [0.97, 1.6] | 0.081 |
| Birth year | 0.996 [0.99, 1.0] | 0.33 |
During the follow-up period (1.1.1998 — 31.12.2019), 75 out of 822 females with CD2_BENIGN_CERVIX_UTERI died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_CERVIX_UTERI.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.128% | No data |
| 5 | 0.776% | No data |
| 10 | 2.011% | No data |
| 15 | 3.774% | No data |
| 20 | 6.605% | No data |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_CERVIX_UTERI – Other benign neoplasm of uterus: Cervix uteri
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data