Other benign neoplasms of uterus

CD2_BENIGN_UTERUS_OTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D26
  • Cause of death: ICD-10 D26

2 out of 7 registries used, show all original rules.

537

4. Check minimum number of events

None

537

5. Include endpoints

2217

6. Filter based on genotype QC (FinnGen only)

1963

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Alia neoplasmata benigna uteri

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 24514 24514 -
Only index persons 19081 19081 -
Unadjusted period prevalence (%)
Whole population 0.70 0.70 -
Only index persons 0.70 0.70 -
Median age at first event (years)
Whole population - 47.18 -
Only index persons - 45.30 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1963 1963 -
Unadjusted period prevalence (%) 0.70 0.70 -
Median age at first event (years) 41.68 41.68 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2022
Matched controls
20220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
21900
ICD-8 Finland
Other benign neoplasm of uterus, Papiloma, polyp
+∞
307.7
1141
*
D26.1
ICD-10 Finland
Other benign neoplasm: Corpus uteri
883.7
244.1
235
*
D26.0
ICD-10 Finland
Other benign neoplasm: Cervix uteri
2041.4
205.7
196
*
21920, ,
ICD-8 Finland
+∞
83.9
80
*
21901, ,
ICD-8 Finland
+∞
82.9
79
*
2191A
ICD-9 Finland
Other benign neoplasm of uterus, Corpus uteri
+∞
78.7
75
*
D26.9
ICD-10 Finland
Other benign neoplasm: Uterus, unspecified
648.2
64.2
63
*
8113
FHL
Fractional scraping
2.8
63.2
388
1602
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
3.5
55.8
204
622
2190A
ICD-9 Finland
Other benign neoplasm of uterus, Cervix uteri
+∞
52.3
50
*
21998
ICD-8 Finland
Other benign neoplasm of uterus, Loco alio definito
+∞
43.9
42
*
21899
ICD-8 Finland
Uterine fibroma
2.5
42.1
298
1303
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
14.2
38.3
35
25
21999
ICD-8 Finland
Other benign neoplasm of uterus, Other and unspecified
+∞
34.5
33
*
6227A
ICD-9 Finland
Noninflammatory disorders of cervix, Mucous polyp of cervix
5.1
32.1
68
137
62620
ICD-8 Finland
Disorders of menstruation, Excessive
3.4
30.7
117
364
62650
ICD-8 Finland
Disorders of menstruation, Irregular
3.8
26.1
82
225
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
2.5
25.9
168
700
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
4.2
22.0
58
140
21910
ICD-8 Finland
Other benign neoplasm of uterus, Benign cyst
+∞
21.9
21
*
N84.1
ICD-10 Finland
Polyp of cervix uteri
3.0
21.6
98
339
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.9
19.8
266
1477
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
3.9
17.9
52
135
62670
ICD-8 Finland
Disorders of menstruation, Postmenopausal bleeding
3.5
17.9
61
177
62699
ICD-8 Finland
Disorders of menstruation, Other
2.2
16.8
140
651
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
2.4
15.7
105
443
LCA06
NOMESCO Finland
Biopsy of endometrium
1.7
13.9
310
1987
LCD00
NOMESCO Finland
Hysterectomy
2.0
13.4
143
732
62000
ICD-8 Finland
Infective diseases of cervix uteri, Cervicitis chronica
4.0
12.7
35
88
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
2.1
12.4
124
620
N84.0
ICD-10 Finland
Polyp of corpus uteri
1.7
11.7
217
1321
8339
FHL
Other measure in this category
9.0
11.7
24
27
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.3
11.3
81
353
62521
ICD-8 Finland
Other diseases of uterus, Hyperplasia glandularis cystica endometrii
3.7
11.2
35
96
ULC02
NOMESCO Finland
Hysteroscopy
2.0
11.2
131
692
00000, ,
ICD-8 Finland
3.4
10.8
39
118
D26.7
ICD-10 Finland
Other benign neoplasm: Other parts of uterus
110.6
10.4
11
*
8305
FHL
Supravaginal amputation or resection
2.4
10.2
71
307
62110
ICD-8 Finland
Other diseases of cervix, Erythroplasia of cervix
9.1
9.5
19
21
H25.8
ICD-10 Finland
Other senile cataract
1.5
9.4
344
2454
D25.1
ICD-10 Finland
Intramural leiomyoma of uterus
1.8
9.3
130
730
8112
FHL
Scraping the cervix
10.1
8.5
16
16
62533
ICD-8 Finland
Other diseases of uterus, Adenomyosis uteri
2.7
8.4
45
172
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
1.6
8.0
187
1210
Z25.1
ICD-10 Finland
Need for immunization against influenza
1.9
7.6
100
552
XLD10
NOMESCO Finland
Gynaecological examination
3.8
7.5
22
58
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
7.4
580
4694
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.6
7.4
193
1281
63494
ICD-8 Finland
Other complications of pregnancy, Insufficientia cervicis
3.6
6.6
21
59
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.5
6.6
242
1726
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
6.5
456
3619
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.9
6.4
81
443
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
1.5
6.3
173
1162
2198X
ICD-9 Finland
Other benign neoplasm of uterus, Other specified parts of uterus
+∞
6.3
6
*
D25.2
ICD-10 Finland
Subserosal leiomyoma of uterus
2.3
6.1
44
194
62801
ICD-8 Finland
Sterility, female, Sterilitas secundaria
3.3
6.1
22
67
62522
ICD-8 Finland
Other diseases of uterus, Polyposis non neoplastica uteri
3.3
6.1
22
67
61520
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Cysta (cystis) follicularis ovarii (retentio)
2.3
6.1
46
207
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
1.5
6.0
170
1148

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
376
2441
1.66
16.25
6.0
5.3
34.34
34.75
%
0.28
235
1467
890
7167
1.43
13.60
4.9
4.1
—
0.77
—
0
22
204
1203
1.77
12.36
3.7
3.5
5.26
5.22
kpa
0.25
184
1133
199
1165
1.79
12.36
3.7
3.5
7.42
7.42
ph
0.49
167
964
961
7955
1.40
12.02
4.5
4.4
53.85
114.81
ng/l
0.57
733
6074
57
215
2.70
10.81
6.2
5.3
7.42
7.40
mmol/l
0.02
47
180
316
2225
1.50
9.24
4.8
4.6
7.38
7.36
ph
0.96
214
1518
1110
9646
1.33
9.10
18.2
17.5
1.30
1.31
inr
0.18
937
8013
915
7819
1.31
8.06
2.4
2.3
—
—
—
0
0
112
634
1.81
7.82
3.9
3.8
25.72
25.14
mmol/l
1.13
99
565
633
5207
1.31
7.14
5.0
4.4
0.01
0.63
estimate
1.52
198
1745
132
812
1.67
6.90
3.8
3.6
—
—
—
0
0
226
1575
1.49
6.89
3.4
4.1
96.64
85.75
u/ml
0.07
219
1513
310
2307
1.41
6.66
3.8
3.2
4.07
4.77
e9/l
1.74
230
1909
751
6391
1.28
6.37
2.6
2.5
62.41
61.10
u/l
0.10
690
5821
184
1265
1.50
6.00
3.3
3.3
4.50
4.40
pmol/l
0.28
165
1098
89
512
1.77
5.96
2.4
2.2
125.43
123.75
g/l
0.32
68
395
849
7383
1.26
5.88
3.4
3.3
1532.49
1526.24
ng/l
0.01
719
6418
1177
10629
1.26
5.85
3.4
3.2
49.75
48.27
u/l
0.20
1074
9646
208
1498
1.43
5.36
6.6
5.0
—
—
—
0
0
1167
10606
1.24
5.16
6.1
6.0
11.21
11.24
umol/l
0.02
1109
10013
1116
10104
1.23
5.08
5.8
5.8
1.23
1.22
mmol/l
4.13
1007
9206
152
1042
1.50
5.06
2.1
2.1
0.00
0.00
estimate
0.50
40
306
560
4708
1.26
5.01
1.9
1.7
124009801.66
21552423.13
pmol/l
1.37
429
3763
591
5008
1.25
4.93
3.7
3.5
—
—
—
0
0
32
141
2.29
4.55
2.7
3.3
—
—
—
0
0
1809
17411
1.37
4.51
19.9
18.8
22.56
24.12
mg/l
1.21
1553
14680
975
8770
1.22
4.51
6.9
6.2
0.66
0.68
%
0.62
893
8110
1567
14802
1.26
4.48
5.5
5.2
15.26
15.16
pmol/l
0.78
1402
13358
1226
11293
1.22
4.40
6.6
6.5
1.23
1.22
mmol/l
3.83
1019
9675
975
8803
1.21
4.24
7.0
6.2
8.72
8.90
%
1.25
888
8137
971
8772
1.21
4.17
6.8
6.1
2.64
2.73
%
0.70
885
8114
986
8922
1.21
4.16
6.7
6.1
26.25
26.93
%
1.07
912
8363
1251
11629
1.20
3.77
4.5
4.5
6.72
6.72
mmol/l
0.00
1198
11011
1851
17966
1.36
3.60
24.3
23.0
139.40
139.48
mmol/l
0.62
1815
17590
35
177
1.99
3.59
1.1
1.1
—
—
—
0
0
960
8745
1.19
3.55
6.6
6.0
59.08
58.12
%
1.58
894
8258
1488
14097
1.21
3.50
5.3
4.8
14.35
15.00
mm/h
0.91
1343
12986
18
70
2.59
3.38
1.1
1.3
5.98
5.75
mmol/l
0.65
18
64
1743
16807
1.27
3.36
7.0
6.5
2.02
2.00
mu/l
0.28
1564
15317
1434
13560
1.20
3.34
7.0
6.3
2689.72
5495.51
e6/l
1.43
39
178
728
6512
1.18
3.25
2.4
2.4
—
—
—
0
0
1751
16909
1.27
3.23
6.0
5.8
5.97
5.98
mmol/l
0.11
1553
15138
507
4395
1.20
3.21
1.9
1.8
1188.39
1186.51
nmol/l
0.01
361
3204
111
787
1.43
3.20
1.9
1.8
2.65
1.50
ug/l
0.40
81
678
234
1864
1.29
3.19
1.4
1.4
—
—
—
0
0
211
1658
1.30
3.19
3.7
4.1
0.09
0.10
%
0.06
68
427
1871
18230
1.35
3.19
27.5
25.4
73.69
73.72
umol/l
0.02
1840
17957
471
4062
1.21
3.14
3.2
3.0
472.43
487.67
mosm/kgh2o
0.88
405
3547
267
2169
1.27
3.11
1.3
1.3
—
—
—
0
0
1885
18396
1.36
3.10
30.8
28.9
6.80
6.76
e9/l
0.23
1844
17869
26
125
2.09
3.08
1.2
1.2
0.12
1.69
u/ml
1.17
17
60
1545
14755
1.20
3.02
8.7
8.0
82.94
80.74
u/l
0.83
1442
13811
1847
17980
1.31
3.02
14.3
13.2
23.78
22.06
u/l
1.45
1763
17318
98
1371
0.70
3.00
7.7
6.5
1.27
1.28
%
0.07
98
1364
266
2171
1.26
2.99
2.4
2.3
0.04
0.02
estimate
0.18
46
391
67
435
1.56
2.98
5.0
4.0
23.68
24.34
mg/l
0.05
49
311
94
1319
0.70
2.93
7.9
6.6
0.66
0.65
%
0.10
94
1313
217
1732
1.28
2.93
3.2
3.6
6.16
6.11
ph
0.31
141
1231
98
1362
0.71
2.90
7.7
6.6
92.52
93.85
%
0.61
98
1356
1883
18396
1.34
2.87
31.1
29.1
128.89
128.82
g/l
0.09
1859
18155
1131
10553
1.16
2.85
5.1
5.0
0.01
3.67
estimate
1.54
270
2324
1846
17988
1.30
2.84
24.6
23.2
3.97
3.96
mmol/l
0.04
1809
17574
1882
18390
1.34
2.81
30.8
28.9
255.82
256.24
e9/l
0.10
1846
17946
661
5923
1.17
2.81
5.2
5.2
0.00
0.00
estimate
0.80
247
2043
35
194
1.82
2.80
2.5
3.4
—
—
—
0
0
1882
18392
1.34
2.79
30.8
28.8
91.27
91.57
fl
2.08
1857
18136
215
1725
1.28
2.79
3.8
4.0
0.64
0.90
%
1.19
73
495
1882
18393
1.34
2.78
30.7
28.8
30.10
30.20
pg
1.76
1857
18137
1882
18393
1.34
2.78
31.2
29.2
38.73
38.65
%
0.25
1857
18135
1882
18393
1.34
2.78
30.8
28.9
4.31
4.30
e12/l
0.76
1843
17869
1116
10419
1.16
2.74
5.2
5.0
0.00
0.00
estimate
0.50
261
2186
157
1212
1.32
2.73
3.6
4.0
1.02
1.02
ratio
0.97
138
1097
42
249
1.70
2.70
1.1
1.1
—
—
—
0
0
205
1648
1.27
2.63
3.9
4.3
0.16
0.25
%
0.18
64
393
834
7639
1.16
2.62
5.2
5.2
0.02
0.70
estimate
1.01
200
1745
1135
10646
1.15
2.52
5.2
5.0
0.03
0.01
estimate
0.43
269
2216
250
2075
1.23
2.44
2.9
3.0
84.29
84.76
ng/l
0.03
190
1709
316
3682
0.83
2.36
3.4
3.1
1.98
1.61
e6/l
0.49
175
1897
12
46
2.62
2.36
1.1
1.5
6.27
5.46
mmol/l
0.36
12
46
930
8634
1.14
2.33
4.0
4.1
—
—
—
0
0
73
1023
0.70
2.31
3.3
3.9
36.88
36.91
°c
0.17
73
1013
174
2144
0.79
2.25
5.8
5.8
94.60
95.54
%
0.66
167
2071
229
1902
1.23
2.23
1.9
2.1
417.48
390.67
nmol/l
1.19
212
1729
911
8465
1.14
2.22
4.0
4.3
6.29
6.36
ph
1.00
487
4434
59
401
1.49
2.20
3.6
3.6
—
—
—
0
0
204
2461
0.81
2.18
5.7
5.6
7.43
7.42
ph
0.62
101
1345
34
205
1.67
2.11
1.1
1.1
6.64
1.51
u/ml
0.87
19
115
163
2007
0.80
2.10
2.4
3.3
179.58
222.97
ng/l
1.18
153
1836
648
5907
1.14
2.08
2.5
2.5
3.20
3.00
mg/l
0.92
528
5063
734
6751
1.14
2.05
2.2
2.2
171.76
173.03
u/l
0.02
674
6338
77
559
1.39
2.05
1.3
1.4
61.67
58.70
mmol/l
0.27
64
454
628
5723
1.14
2.02
3.1
2.9
29.86
33.06
u/l
1.38
585
5326
47
311
1.52
2.01
2.7
3.4
0.85
1.66
%
2.44
39
272
462
5154
0.87
2.00
4.4
4.8
0.00
0.76
—
10
78
416
3685
1.16
1.99
2.4
2.5
11.55
11.54
umol/l
0.01
361
3381
329
2861
1.18
1.98
1.3
1.2
—
—
—
0
0
16
77
2.09
1.96
1.1
7.2
95.13
62.62
mg/l
—
8
48
1060
9998
1.13
1.94
2.7
2.6
81.65
81.94
nmol/l
0.11
901
8806
287
2473
1.19
1.93
1.3
1.3
—
—
—
0
0
198
1651
1.22
1.89
3.4
3.9
0.43
0.69
%
1.69
67
469
132
1056
1.27
1.83
2.0
1.7
1.86
1.33
g/l
0.80
114
936
79
589
1.36
1.82
4.0
5.2
—
—
—
0
0
7
23
3.05
1.80
4.9
3.7
1.14
0.91
u/field
—
7
23
957
9002
1.12
1.78
2.8
2.7
—
—
estimate
—
0
0
37
241
1.55
1.73
1.2
1.5
0.65
0.70
g/l
0.20
30
192
166
1994
0.82
1.73
2.9
2.4
46.60
40.02
u/l
0.42
145
1654
1007
9513
1.12
1.72
6.4
5.9
0.59
0.59
e9/l
0.13
853
7977
1038
9823
1.12
1.71
6.6
6.1
0.18
0.18
e9/l
0.87
884
8355
387
3449
1.15
1.71
2.3
2.4
2.37
2.34
g/l
0.58
332
3145
209
2452
0.84
1.70
5.6
5.6
5.11
5.11
kpa
0.01
198
2349
209
2451
0.84
1.70
5.6
5.6
12.03
12.15
kpa
0.12
199
2343
208
2439
0.84
1.69
5.4
5.6
1.39
1.26
mmol/l
0.19
173
2015
0
49
0.00
1.68
0.0
1.6
—
2920.00
—
0
8
739
6869
1.12
1.67
1.9
1.8
20.19
21.47
nmol/l
1.46
582
5688
65
477
1.37
1.67
2.1
2.4
1.73
1.63
mg/l
0.44
57
414
1009
9543
1.11
1.67
6.5
5.9
0.04
0.04
e9/l
0.56
854
8006
25
149
1.69
1.67
3.0
2.8
24.06
13.65
mg/l
0.40
19
101
23
134
1.72
1.66
1.0
1.0
6.30
1.91
u/ml
0.49
11
65
17
90
1.90
1.65
2.5
1.8
517.17
332.71
mu/l
0.61
12
72
1341
13913
0.89
1.64
25.8
23.6
13.91
13.89
%
0.16
1332
13701
29
181
1.61
1.63
1.3
1.2
—
—
—
0
0
54
386
1.41
1.62
2.7
4.0
2.88
3.07
mmol/l
0.23
38
276
1025
9714
1.11
1.61
6.5
5.9
1.86
1.86
e9/l
0.03
885
8331
213
1820
1.19
1.60
1.5
1.5
—
—
—
0
0
77
586
1.33
1.58
1.6
1.9
3.49
13.88
iu/l
0.49
23
223
38
255
1.50
1.58
1.2
1.3
304.32
302.73
pmol/l
0.01
32
216
1693
16524
1.15
1.56
7.4
7.1
40.05
39.88
mmol/mol
0.37
1516
15127
157
1875
0.82
1.56
2.0
2.5
8.43
5.51
ug/l
0.82
109
1569
158
1316
1.22
1.56
2.7
2.9
10.99
10.50
g/l
0.59
145
1193
37
248
1.50
1.55
3.0
2.7
—
—
—
0
0
719
6697
1.11
1.55
3.9
4.0
7.65
7.88
mg/mmol
0.04
352
3808
21
122
1.73
1.54
1.0
1.1
3.59
2.68
u/ml
—
8
53
20
115
1.75
1.52
2.0
1.4
—
—
—
0
0
95
1192
0.79
1.50
2.4
2.3
1.12
1.10
%
0.09
95
1184
194
2262
0.84
1.49
2.9
2.9
5.71
5.83
kpa
0.85
188
2204
76
585
1.31
1.46
13.1
10.9
—
—
—
0
0
631
5852
1.11
1.46
4.3
4.0
—
—
—
0
0
14
253
0.55
1.44
1.1
1.2
1.59
1.63
g/l
0.18
14
253
300
2661
1.15
1.43
3.8
4.2
1.03
1.05
mmol/l
0.31
263
2397
25
157
1.60
1.40
1.1
1.1
—
—
—
0
0
475
4347
1.12
1.39
1.3
1.3
1.02
1.54
u/ml
0.97
105
1050
1234
12808
0.91
1.38
4.7
4.6
—
0.32
—
0
28
8
165
0.48
1.35
1.3
1.3
—
—
—
0
0
101
817
1.25
1.34
3.8
2.9
34.79
45.65
mg/l
0.85
87
719
468
5091
0.89
1.33
3.2
3.0
2.49
2.48
mmol/l
1.25
430
4555
43
308
1.40
1.32
1.2
1.1
—
—
—
0
0
23
144
1.60
1.32
1.1
1.0
1.21
0.61
u/ml
—
10
74
37
258
1.44
1.32
1.3
1.3
—
—
nmol/l
—
0
0
189
2182
0.85
1.31
2.9
3.0
1.87
2.12
mmol/l
0.50
166
1921
16
270
0.59
1.31
1.1
1.2
0.88
0.90
g/l
0.05
16
270
145
1223
1.20
1.30
1.2
1.2
128.60
131.38
u/ml
0.03
52
457
33
227
1.46
1.26
4.9
6.0
12.25
13.44
mg/l
0.99
28
207
165
1412
1.18
1.26
1.2
1.3
—
—
—
0
0
772
7280
1.10
1.26
2.0
1.9
1.34
1.30
mmol/l
0.65
579
6007
24
363
0.66
1.25
1.0
1.2
13.61
30.85
e6/l
0.42
18
268
35
245
1.44
1.23
1.6
1.9
90.97
89.34
%
1.77
35
240
153
1787
0.84
1.23
6.4
5.9
—
—
—
0
0
97
1183
0.81
1.23
2.4
2.3
0.66
0.62
%
0.53
97
1177
148
1258
1.19
1.23
2.8
2.6
—
—
—
0
0
215
1885
1.16
1.22
3.4
3.5
1.24
1.24
mmol/l
0.03
172
1608
100
818
1.23
1.22
3.9
2.9
40.87
112.31
mg/l
0.59
86
725
8
37
2.17
1.21
5.0
2.7
—
—
—
0
0
58
444
1.32
1.20
2.4
3.1
47.61
1240.97
u/ml
1.21
52
397
88
711
1.25
1.20
1.6
1.6
30.71
20.48
u/ml
—
9
96
124
1040
1.20
1.19
1.3
1.3
119.16
167.69
u/ml
0.94
112
964
69
542
1.28
1.19
2.4
2.4
—
—
—
0
0
35
487
0.71
1.18
1.0
1.1
—
—
—
0
0
351
3187
1.12
1.18
2.4
2.5
18.98
19.83
%
0.70
302
2921
38
273
1.40
1.18
1.1
1.2
0.20
0.19
nmol/l
0.25
33
211
166
1434
1.17
1.15
1.4
1.4
—
—
—
0
0
33
232
1.43
1.15
2.7
2.9
—
—
—
0
0
5
20
2.50
1.15
1.0
1.1
—
—
—
0
0
5
112
0.45
1.13
1.4
1.4
—
—
—
0
0
711
6724
1.09
1.06
3.1
3.2
6.05
5.94
mmol/l
0.23
532
5554
6
124
0.48
1.05
1.7
1.7
9.55
8.80
mmol/l
—
6
124
33
237
1.40
1.04
1.2
1.2
—
—
—
0
0
183
1608
1.15
1.04
2.7
2.4
0.27
0.62
e6/l
2.74
171
1537
15
90
1.67
1.04
3.3
1.5
40.03
38.80
g/l
0.29
15
90
29
205
1.42
1.01
3.4
2.3
3.38
1.43
u/field
1.09
13
103
28
198
1.42
0.98
2.6
2.9
55.40
57.29
%
0.19
20
165
168
1906
0.87
0.97
5.6
5.1
1.37
1.31
mmol/l
0.43
163
1868
201
2253
0.88
0.97
2.9
3.0
7.39
7.38
ph
0.33
114
1280
492
4597
1.09
0.96
1.4
1.4
—
—
—
0
0
0
31
0.00
0.96
0.0
1.2
—
137.67
—
0
15
693
6571
1.08
0.96
3.1
3.3
36.11
35.42
mg/l
0.03
341
3866
58
461
1.27
0.96
1.1
1.2
154.29
108.48
titre
—
7
33
107
908
1.19
0.95
1.8
1.9
3.13
3.25
ratio
0.50
71
727
41
311
1.32
0.95
2.8
2.2
30.29
31.77
umol/l
0.19
35
268
377
3482
1.10
0.94
3.1
2.6
0.81
0.81
mmol/l
0.05
346
3203
1698
16695
1.11
0.93
5.7
5.3
4.71
4.68
mmol/l
0.51
1517
15082
21
142
1.48
0.92
1.0
1.2
—
—
—
0
0
49
620
0.79
0.91
1.3
1.2
—
—
—
0
0
36
270
1.34
0.91
2.2
1.8
10961.40
2903.45
u/l
0.60
15
119
136
1184
1.16
0.90
2.3
2.5
14.32
25.08
au/ml
—
6
89
87
730
1.20
0.89
3.8
2.8
2.90
5.48
ratio
0.71
53
441
29
211
1.38
0.88
1.2
1.5
20.69
22.75
ng/l
0.26
29
211
385
3573
1.10
0.88
1.5
1.5
2.43
2.43
g/l
0.00
211
1933
848
8127
1.07
0.88
3.5
3.4
2.38
2.37
mmol/l
0.40
740
7253
6
31
1.94
0.84
1.0
1.1
—
—
—
0
0
215
1941
1.12
0.84
3.1
2.5
66.25
66.10
g/l
0.10
178
1724
245
2229
1.11
0.84
2.3
2.3
10.35
8.22
umol/l
0.46
213
1896
271
2479
1.11
0.83
3.3
3.9
7.60
15.21
ug/l
1.01
220
2030
361
3350
1.09
0.83
1.3
1.3
11.33
13.77
u/ml
0.28
120
1158
1735
17100
1.10
0.82
6.4
6.3
2.69
2.65
mmol/l
1.39
1537
15436
30
223
1.35
0.82
1.0
1.0
—
—
—
0
0
1019
9848
1.07
0.81
4.6
4.4
34.61
34.98
g/l
1.34
928
9120
911
8775
1.07
0.80
3.4
3.1
104.22
107.26
ug/l
0.22
814
8003
36
462
0.78
0.78
2.0
1.4
0.25
0.27
mg/l
—
8
153
1604
15766
1.08
0.77
4.7
4.4
1.29
1.25
mmol/l
1.93
1405
13908
32
244
1.32
0.75
1.0
1.0
—
—
—
0
0
401
4272
0.92
0.74
4.3
4.3
190.82
220.85
ng/l
0.17
328
3601
21
150
1.40
0.73
1.7
1.5
0.34
0.33
nmol/l
0.02
16
118
227
2076
1.11
0.72
1.9
2.0
0.20
0.20
g/l
0.06
207
1923
9
56
1.61
0.72
1.1
1.0
—
—
—
0
0
9
56
1.61
0.72
1.1
1.0
—
—
—
0
0
9
56
1.61
0.72
1.1
1.0
—
—
—
0
0
39
308
1.27
0.72
1.2
1.1
—
—
—
0
0
50
610
0.82
0.72
4.3
5.1
1.23
1.24
mmol/l
0.03
43
552
5
26
1.93
0.70
1.0
1.0
—
—
—
0
0
494
4679
1.07
0.70
2.8
2.6
332.86
334.68
umol/l
0.14
392
3974
563
5909
0.93
0.70
7.5
6.3
—
—
—
0
0
9
58
1.55
0.69
1.7
1.8
—
—
—
0
0
9
143
0.63
0.69
1.7
1.5
—
—
—
0
0
223
2043
1.10
0.69
2.3
2.3
68.17
70.28
e9/l
0.42
169
1456
107
1216
0.87
0.68
6.7
6.6
25.07
24.56
mmol/l
0.76
99
1181
10
61
1.64
0.68
1.3
1.5
74.00
537.02
nmol/24h
—
10
61
278
2578
1.09
0.67
2.3
2.4
1.79
1.87
%
0.69
228
2258
24
179
1.34
0.67
1.0
1.1
2.96
2.31
eliau/ml
0.13
11
59
173
1569
1.11
0.66
1.2
1.2
—
—
—
0
0
7
44
1.59
0.65
1.0
1.2
—
—
—
0
0
21
156
1.35
0.61
1.1
1.1
—
—
—
0
0
158
1434
1.11
0.61
1.5
1.6
—
—
—
0
0
52
435
1.20
0.60
1.8
1.9
4.55
4.50
mmol/24h
0.04
43
363
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
9
140
0.64
0.60
1.7
1.4
—
—
—
0
0
13
186
0.70
0.59
1.2
1.1
—
—
—
0
0
81
707
1.15
0.58
2.9
2.8
445.04
381.16
mg/l
0.16
27
237
252
2346
1.08
0.58
1.9
1.9
119.06
150.37
ug/g
1.06
180
1811
15
106
1.42
0.57
1.7
1.5
46.81
41.20
%
0.73
15
106
6
37
1.62
0.55
1.0
1.2
—
—
—
0
0
31
248
1.25
0.55
1.2
1.2
—
—
—
0
0
23
177
1.30
0.54
1.0
1.1
1.58
1.54
g/l
0.18
18
154
23
177
1.30
0.54
1.1
1.1
39.28
34.31
mmol/l
0.50
18
151
456
4348
1.06
0.54
1.8
1.8
1.30
1.37
mg/l
0.19
354
3384
9
60
1.50
0.54
1.2
1.9
—
—
—
0
0
34
276
1.24
0.54
1.6
1.3
280.48
271.26
mosm/kgh2o
1.16
21
195
16
215
0.74
0.52
1.1
1.1
—
—
—
0
0
29
232
1.25
0.52
1.5
1.4
—
—
—
0
0
88
781
1.13
0.51
1.5
1.5
—
—
—
0
0
22
170
1.30
0.51
1.0
1.1
—
—
—
0
0
9
64
1.41
0.51
1.3
1.5
26.89
30.25
%
—
9
64
11
75
1.47
0.50
1.5
1.3
37.50
39.43
g/l
—
6
38
235
2197
1.08
0.50
1.4
1.4
—
—
—
0
0
1673
16544
1.07
0.49
5.7
5.2
1.57
1.59
mmol/l
0.72
1483
14848
118
1070
1.11
0.49
1.3
1.3
75.40
52.42
au/ml
—
5
72
64
559
1.15
0.48
1.4
1.3
5.21
3.12
u/ml
—
9
59
19
245
0.77
0.48
3.1
3.1
11.33
12.03
index
—
9
110
241
2261
1.07
0.47
2.1
1.8
—
—
—
0
0
516
4962
1.05
0.46
2.3
2.3
—
—
—
0
0
15
111
1.35
0.46
1.0
1.1
—
—
—
0
0
26
319
0.81
0.45
1.6
1.3
171.55
245.67
miu/ml
0.37
11
127
32
265
1.21
0.44
1.4
1.7
—
—
—
0
0
86
772
1.12
0.44
3.8
3.6
0.92
0.81
nmol/l
0.53
70
629
29
238
1.22
0.44
1.7
1.6
58.50
57.45
%
0.06
20
158
7
51
1.37
0.44
1.7
1.3
—
—
—
0
0
264
2494
1.07
0.44
1.3
1.3
870.86
562.99
titre
1.17
70
628
475
4935
0.95
0.43
3.9
3.8
86.60
89.64
%
1.70
463
4814
8
56
1.43
0.42
1.1
1.2
25.90
19.65
%
—
8
51
26
212
1.23
0.42
1.3
1.2
151.00
165.27
au/ml
—
7
64
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
0.98
—
0
8
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
17
132
1.29
0.40
1.3
1.4
—
—
—
0
0
55
624
0.88
0.40
3.9
3.5
0.65
2.06
index
1.89
23
287
80
722
1.11
0.39
1.5
1.4
297.78
272.13
ug/g
0.48
50
419
109
1001
1.09
0.38
3.1
2.2
3.80
3.71
g/l
0.15
86
880
109
1002
1.09
0.37
3.1
2.2
4.25
4.31
g/l
0.31
86
879
60
673
0.89
0.37
1.3
1.2
—
—
—
0
0
11
147
0.75
0.37
2.3
2.4
—
—
—
0
0
29
343
0.84
0.36
1.0
1.2
—
—
—
0
0
21
171
1.23
0.35
1.1
1.0
2.34
1.57
u/ml
—
7
77
44
385
1.15
0.35
1.6
1.4
—
—
—
0
0
203
1920
1.06
0.35
1.5
1.6
—
—
—
0
0
44
386
1.14
0.34
3.4
3.2
61.27
59.15
%
0.62
44
386
479
4637
1.04
0.34
2.9
2.8
8.74
7.71
e6/l
0.38
429
4216
80
729
1.10
0.34
1.3
1.2
5.38
0.38
u/ml
—
6
61
25
209
1.20
0.34
1.7
1.3
—
—
—
0
0
25
209
1.20
0.34
1.7
1.3
—
—
—
0
0
25
209
1.20
0.34
1.7
1.3
—
—
—
0
0
25
209
1.20
0.34
1.7
1.3
—
—
—
0
0
13
100
1.30
0.33
1.5
1.8
1.22
6.92
nmol/l
—
8
84
16
127
1.26
0.33
1.3
1.2
—
—
—
0
0
36
312
1.16
0.33
1.3
1.2
23.74
27.60
u/l
0.28
30
265
14
177
0.79
0.33
1.0
1.2
—
—
—
0
0
62
559
1.11
0.32
1.4
1.3
1.99
8.03
u/ml
1.98
15
107
20
164
1.22
0.32
1.2
1.0
0.28
1.59
u/ml
—
7
68
113
1050
1.08
0.32
1.7
1.7
1.66
1.57
g/l
0.45
90
903
48
539
0.89
0.32
1.6
1.8
—
—
—
0
0
11
84
1.31
0.30
2.1
2.0
570.33
489.81
min
—
6
59
13
102
1.28
0.30
1.4
1.3
7.87
8.82
mmol/l
0.28
13
95
74
679
1.09
0.29
1.6
1.7
3.44
3.42
mmol/l
0.05
37
492
569
5829
0.97
0.27
3.6
3.4
0.73
0.55
e6/l
0.61
424
4256
370
3582
1.04
0.27
1.4
1.3
38.27
35.46
iu/ml
0.14
110
1122
8
67
1.19
0.26
1.1
1.1
—
—
—
0
0
8
67
1.19
0.26
1.1
1.1
2243.00
1670.00
miu/ml
—
8
67
567
5539
1.03
0.26
3.9
3.7
0.11
0.05
0.25
18
220
48
434
1.11
0.26
1.1
1.1
—
—
—
0
0
1106
10917
1.03
0.25
9.5
9.1
4.33
4.14
e9/l
0.99
954
9388
95
888
1.07
0.25
2.9
2.2
9.83
10.13
g/l
0.28
67
756
14
114
1.23
0.25
1.4
1.1
—
—
—
0
0
19
223
0.85
0.24
2.2
2.1
0.90
0.82
g/24h
—
8
122
32
284
1.13
0.23
1.2
1.1
—
—
—
0
0
16
134
1.20
0.23
1.2
1.3
—
—
—
0
0
828
8153
1.03
0.22
14.0
12.1
0.00
0.00
e9/l
1.40
695
6542
15
125
1.20
0.22
2.2
1.6
1151.07
1128.03
e6/l
0.03
15
111
10
79
1.27
0.22
1.1
1.1
1.02
1.05
ratio
—
10
60
5
42
1.19
0.21
1.0
1.3
—
28.71
—
0
7
127
1208
1.05
0.21
2.1
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
6.44
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
8
104
0.77
0.21
1.3
1.7
94.25
77.16
umol/l
—
8
104
10
80
1.25
0.20
1.0
1.3
134.10
137.37
mmol/24h
—
10
80
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
9
111
0.81
0.20
3.6
1.6
—
—
—
0
0
6
49
1.23
0.20
2.0
2.3
184.17
148.61
nmol/l
—
6
44
64
597
1.07
0.19
1.3
1.3
—
—
—
0
0
42
458
0.92
0.19
1.0
1.1
—
—
—
0
0
100
950
1.06
0.18
1.3
1.4
—
—
—
0
0
75
796
0.94
0.18
1.0
1.1
—
205.79
—
0
19
29
321
0.90
0.18
1.5
1.3
—
—
—
0
0
7
59
1.19
0.18
2.1
2.4
0.00
0.05
estimate
—
7
59
176
1698
1.04
0.18
5.0
5.4
10.44
10.22
mmol/l
0.13
162
1605
5
70
0.71
0.16
1.4
1.2
—
—
—
0
0
12
101
1.19
0.16
1.1
1.0
—
—
—
0
0
11
130
0.85
0.16
1.0
1.1
—
9.67
—
0
32
13
151
0.86
0.15
2.0
1.5
—
—
—
0
0
15
172
0.87
0.15
1.1
1.1
—
—
—
0
0
59
555
1.06
0.15
2.0
1.6
3785.20
14594.41
e6/l
4.45
35
379
95
993
0.95
0.15
1.3
1.2
—
—
—
0
0
21
234
0.90
0.15
1.8
2.4
—
—
—
0
0
15
171
0.88
0.14
1.1
1.1
—
—
—
0
0
10
84
1.19
0.14
2.0
1.2
253.40
328.17
u/l
—
10
77
8
97
0.82
0.13
1.3
1.5
—
—
—
0
0
1007
9987
1.02
0.13
2.5
2.3
101.86
97.74
pmol/l
1.44
494
4721
55
520
1.06
0.13
2.1
1.5
—
—
—
0
0
296
3020
0.98
0.13
2.4
1.9
29.53
29.37
s
0.17
286
2912
20
221
0.90
0.12
1.6
1.4
54260.25
84744.06
e6/l
0.20
12
117
12
104
1.15
0.12
1.7
1.5
11.42
16.45
%
1.36
12
97
17
152
1.12
0.12
2.2
2.1
—
—
—
0
0
33
307
1.08
0.12
2.4
1.8
0.78
0.88
%
0.60
20
201
81
778
1.04
0.11
1.6
1.7
13.24
6.38
iu/ml
1.03
17
190
22
201
1.10
0.11
1.5
1.4
—
—
—
0
0
379
3732
1.02
0.11
4.5
4.7
—
—
—
0
0
14
124
1.13
0.11
1.3
1.2
270.00
150.50
titre
—
6
20
17
153
1.11
0.11
4.5
1.6
3.45
4.29
mg/l
0.48
17
147
748
7549
0.99
0.11
4.7
4.3
154.83
133.40
e6/l
0.20
537
5179
13
115
1.13
0.10
2.1
1.3
16.05
21.22
umol/l
0.36
13
101
16
144
1.11
0.10
1.2
1.2
—
—
—
0
0
84
811
1.04
0.10
1.4
1.4
—
—
—
0
0
281
2764
1.02
0.10
1.9
1.9
—
—
—
0
0
672
6662
1.01
0.09
3.7
3.5
122.32
44.47
e6/l
0.67
511
5008
28
262
1.07
0.09
1.4
1.3
—
—
—
0
0
26
243
1.07
0.08
2.0
2.9
—
—
—
0
0
98
954
1.03
0.08
1.3
1.2
—
—
—
0
0
77
794
0.97
0.08
2.6
3.0
73.59
1499.56
u/ml
1.06
61
668
16
174
0.92
0.07
1.4
1.4
—
—
—
0
0
10
112
0.89
0.07
1.9
1.9
15.43
15.82
%
—
10
112
9
100
0.90
0.06
1.3
1.2
—
—
—
0
0
12
109
1.10
0.06
1.7
1.5
74.83
73.48
%
0.13
12
100
37
355
1.04
0.06
2.9
2.2
33.54
58.38
ug/min
0.56
17
199
704
7075
0.99
0.05
3.9
3.8
7.40
7.40
ph
0.46
499
5056
30
313
0.96
0.05
1.3
1.6
0.85
0.84
nmol/l
0.01
24
255
100
982
1.02
0.04
1.3
1.3
—
—
—
0
0
20
211
0.95
0.04
2.1
1.7
—
—
—
0
0
329
3309
0.99
0.03
3.5
3.2
5.26
4.67
e6/l
0.35
187
1512
18
189
0.95
0.03
1.3
1.2
153.61
104.93
pmol/l
2.10
18
189
12
112
1.07
0.03
2.2
2.2
490.33
632.09
ml
—
6
70
21
202
1.04
0.02
1.4
1.4
—
—
—
0
0
22
212
1.04
0.02
1.8
1.4
—
—
—
0
0
21
218
0.96
0.02
3.3
3.3
4.93
31.33
nmol/l
0.52
21
208
13
123
1.06
0.01
1.0
1.2
—
—
—
0
0
39
398
0.98
0.01
1.1
1.2
—
—
—
0
0
15
143
1.05
0.01
1.1
1.4
—
—
—
0
0
22
214
1.03
0.00
1.4
1.3
—
—
—
0
0
469
4697
1.00
0.00
4.8
5.4
1.02
1.02
kg/l
0.66
311
3166
14
135
1.04
0.00
1.2
1.1
—
—
—
0
0
11
111
0.99
0.00
1.3
1.4
5.67
5.44
u/l
—
6
93
22
215
1.02
0.00
1.4
1.4
—
—
—
0
0
22
215
1.02
0.00
1.4
1.3
—
—
—
0
0
20
199
1.01
0.00
1.9
1.6
—
—
—
0
0
62
625
0.99
0.00
2.0
1.8
20.81
21.19
s
0.19
53
564
10
96
1.04
0.00
2.5
5.1
—
—
—
0
0
170
1696
1.00
0.00
1.7
1.6
—
—
—
0
0
14
142
0.99
0.00
1.1
1.2
—
—
—
0
0
17
172
0.99
0.00
1.6
1.6
43.55
32.96
%
0.48
11
107
20
202
0.99
0.00
1.2
1.1
296.00
273.19
u/ml
0.18
14
115
10
102
0.98
0.00
2.5
4.9
—
—
—
0
0
18
183
0.98
0.00
1.9
1.6
—
—
—
0
0
6
68
0.88
0.00
1.2
1.3
—
0.43
—
0
5
0
6
0.00
0.00
0.0
1.2
—
152.83
—
0
6
0
5
0.00
-0.00
0.0
1.6
—
248.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
74
0.95
-0.00
1.1
1.2
136.71
143.51
nmol/l
—
7
74
20
200
1.00
-0.00
1.3
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
256.57
—
0
7
7
76
0.92
-0.00
3.7
1.7
198.00
224.86
e6/l
—
7
64
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
78
0.90
-0.00
1.3
1.3
0.59
1.44
nmol/l
—
7
64
21
210
1.00
-0.00
1.3
1.4
—
—
—
0
0
22
220
1.00
-0.00
1.1
1.2
3.00
4.40
u/ml
0.50
13
92
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
3.0
1.6
451.71
460.36
e6/l
—
7
59
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
20.96
—
0
7
0
9
0.00
-0.00
0.0
2.0
—
265.52
—
0
9
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
4.22
—
0
5

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_UTERUS_OTH and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_UTERUS_OTH 1.198 [1.02, 1.4] 0.025
Birth year 0.999 [0.99, 1.01] 0.86

During the follow-up period (1.1.1998 — 31.12.2019), 235 out of 2089 females with CD2_BENIGN_UTERUS_OTH died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_UTERUS_OTH.

N-year risk Females Males
1 0.115% No data
5 0.738% No data
10 1.962% No data
15 3.867% No data
20 6.731% No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_UTERUS_OTH – Other benign neoplasms of uterus

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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