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ILD medications: acetylcysteine

ILD_ASETYLCYSTEINE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC R05CB01

1 out of 7 registries used, show all original rules.

402

4. Check minimum number of events

Min. number of events 3
402

5. Include endpoints

None

402

6. Filter based on genotype QC (FinnGen only)

357

Control definitions (FinnGen only)

Control exclude
ILD_MEDICATIONS

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 357 152 205
Unadjusted period prevalence (%) 0.08 0.05 0.09
Median age at first event (years) 61.55 53.77 67.31

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
367
Matched controls
3670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R05CB01
ATC
acetylcysteine; inhalant, oral
+∞
307.7
367
27
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
18.8
188.5
222
276
R03AC12
ATC
salmeterol; inhalant
35.4
185.6
127
54
R03DA04
ATC
theophylline; systemic, rectal
16.4
144.2
150
148
R03BB01
ATC
ipratropium bromide; inhalant
16.8
133.3
132
119
H02AB06
ATC
prednisolone; systemic
10.6
110.6
262
697
H02AB07
ATC
prednisone; oral
13.4
107.6
120
128
R03AK06
ATC
salmeterol and fluticasone; inhalant
11.0
105.4
145
206
R03BA05
ATC
fluticasone; inhalant
10.4
104.2
154
239
R03AK03
ATC
[U] fenoterol and ipratropium bromide
11.5
103.7
134
175
H02AB04
ATC
methylprednisolone; systemic
11.4
93.5
117
145
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
8.8
91.7
158
289
J45.9
ICD-10 Finland
Asthma, unspecified
9.5
91.1
139
221
R03BA02
ATC
budesonide; inhalant
9.0
86.3
139
234
R03BA01
ATC
beclometasone; inhalant
8.8
77.9
122
197
J45.1
ICD-10 Finland
Nonallergic asthma
14.9
72.2
69
56
R03AC03
ATC
terbutaline; inhalant
8.2
64.5
102
164
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
18.5
60.1
50
31
R03DC03
ATC
montelukast; oral
8.4
59.9
90
136
R03AC13
ATC
formoterol; inhalant
11.8
56.5
62
62
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
9.2
55.2
75
100
J45.0
ICD-10 Finland
Predominantly allergic asthma
13.9
54.3
53
44
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
15.6
53.8
49
36
R03BB04
ATC
tiotropium bromide; inhalant
6.9
53.6
99
186
R03AC02
ATC
salbutamol; inhalant
4.9
48.1
243
1048
J01FA06
ATC
roxithromycin; oral
3.8
35.1
202
897
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
7.2
32.5
52
82
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
52.8
32.2
38
8
J01AA02
ATC
doxycycline; systemic
5.6
30.7
322
2063
R05CB02
ATC
bromhexine; systemic
10.1
29.6
35
38
J46
ICD-10 Finland
Status asthmaticus
44.1
29.6
36
9
R03AK07
ATC
formoterol and budesonide; inhalant
4.5
28.3
81
217
J96.1
ICD-10 Finland
Chronic respiratory failure
11.2
27.5
30
29
R03DC01
ATC
zafirlukast; oral
27.3
27.2
37
15
R01AD08
ATC
fluticasone; nasal
3.6
25.6
109
385
J45
ICD-10 Finland
Asthma
5.5
21.0
43
86
J01FA10
ATC
azithromycin; systemic
2.8
20.4
177
921
R05CB03
ATC
carbocisteine; oral
7.3
20.3
31
46
J01FA09
ATC
clarithromycin; systemic
3.1
20.1
110
446
J45.8
ICD-10 Finland
Mixed asthma
24.2
19.4
27
12
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.4
19.1
82
287
A01AB09
ATC
miconazole; local oral
3.9
19.1
62
180
J01DA06
ATC
[U] cefuroxime
3.6
18.8
72
234
A01AB10
ATC
natamycin; local oral
6.9
18.2
29
45
J47
ICD-10 Finland
Bronchiectasis
17.7
18.2
28
17
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.6
18.1
169
899
J01MA14
ATC
moxifloxacin; systemic
4.4
18.1
49
124
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.0
17.7
95
378
R06AE07
ATC
cetirizine; oral
2.7
17.7
145
722
R05FB02
ATC
cough suppressants and expectorants; systemic
2.6
17.6
187
1055
A01AB04
ATC
amphotericin B; local oral
4.8
17.3
41
93
4931B
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA CUM EXACERBATIONE]
52.7
17.2
20
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.1
16.1
47
126
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.7
16.0
57
176
J01DA01
ATC
[U] cefalexin
2.6
15.9
248
1645
49300
ICD-8 Finland
Asthma, bronchiale
12.0
15.5
28
25
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
5.4
14.8
30
59
J01FA01
ATC
erythromycin; systemic
3.6
14.6
54
170
R01BA52
ATC
pseudoephedrine, combinations; oral
2.6
14.1
99
450
4931A
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA SINE EXACERBATIONE]
21.1
13.9
20
10
L01BA01
ATC
methotrexate; systemic
78.1
13.7
15
*
A07AA02
ATC
nystatin; oral
4.2
13.6
38
98
R05DA20
ATC
opium alkaloids and derivatives - combinations
2.5
13.4
107
515
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.3
13.4
159
914
J01FA15
ATC
telithromycin; oral
4.2
13.3
37
95
R03BB02
ATC
oxitropium bromide; inhalant
17.5
13.1
20
12
A02BA04
ATC
nizatidine; systemic
3.3
12.9
54
184
A02BA02
ATC
ranitidine; systemic
2.4
12.8
112
561
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
16.2
12.8
20
13
R96
ICPC
Asthma
4.0
12.6
37
99
J01DA08
ATC
[U] cefaclor
3.9
12.1
37
102
N05BA01
ATC
diazepam; systemic, rectal
2.8
12.0
66
263
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
67.2
11.7
13
*
J02AC01
ATC
fluconazole; systemic
2.3
11.6
124
675
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
12.4
11.5
20
17
M05BA04
ATC
alendronic acid; oral
3.1
11.3
51
181
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.8
11.2
35
98
R05DB05
ATC
pentoxyverine; oral, rectal
4.9
11.1
25
54
R03BC03
ATC
nedocromil; inhalant
3.8
10.9
35
100
N02AC04
ATC
dextropropoxyphene; oral
3.6
10.4
36
108
J01MA12
ATC
levofloxacin; systemic
2.4
10.4
85
409
R06AX12
ATC
terfenadine; oral
5.1
10.4
22
45
C03CA01
ATC
furosemide; systemic
2.1
10.3
194
1296
R03DA54
ATC
theophylline, combinations excl. psycholeptics; systemic
9.5
10.1
20
22
M09AA72
ATC
quinine, combinations with psycholeptics; systemic
3.3
10.1
39
126
J01DA09
ATC
[U] cefadroxil
2.2
9.8
104
558
C01AA05
ATC
digoxin; systemic
2.3
9.7
85
421
R05FA02
ATC
opium derivatives and expectorants; systemic
2.0
9.6
147
905
51899
ICD-8 Finland
Bronchiectasis
30.9
9.5
12
*
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
30.9
9.5
12
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
8.1
9.3
20
26
C08DA01
ATC
verapamil; systemic
3.5
9.1
33
102
R01AD05
ATC
budesonide; nasal
3.5
9.1
32
97
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
16.1
9.1
14
9
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.7
9.0
21
47
N06AB03
ATC
fluoxetine; oral
2.8
8.9
47
182
R06AX13
ATC
loratadine; oral
2.9
8.8
45
171
N05CF01
ATC
zopiclone; oral
2.0
8.7
154
992
R03DA05
ATC
aminophylline; systemic, rectal
10.4
8.6
16
16
4940A
ICD-9 Finland
Bronchiectasis[BRONCHIECTASIAE]
92.1
8.4
9
*
R03AK11
ATC
formoterol and fluticasone; inhalant
13.2
8.4
14
11
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
11.1
8.4
15
14
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.4
8.1
30
94
R01AD01
ATC
beclometasone; nasal
2.6
8.1
52
223
L04AX03
ATC
methotrexate; systemic
22.6
8.1
11
5
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
4.1
8.0
22
56
G47.3
ICD-10 Finland
Sleep apnoea
2.4
8.0
57
257
J01MA01
ATC
ofloxacin; systemic
2.5
7.8
52
226
M01CB01
ATC
sodium aurothiomalate; parenteral
46.0
7.7
9
*
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.9
7.7
151
995
A02BA03
ATC
famotidine; systemic
3.3
7.7
29
92
R04.2
ICD-10 Finland
Haemoptysis
3.8
7.6
23
63
A02BC01
ATC
omeprazole; systemic
1.9
7.5
115
699
R01AD09
ATC
mometasone; nasal
1.9
7.5
113
683
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.0
7.5
109
651
A98
ICPC
Health maint/preventive medicine
0.5
7.5
165
2201
A12BA01
ATC
potassium chloride; oral
2.6
7.3
44
183
N05CD07
ATC
temazepam; oral
2.1
7.2
81
440
P01BA02
ATC
hydroxychloroquine; oral
4.5
7.0
17
39
R06AE09
ATC
levocetirizine; oral
2.8
7.0
35
132
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.5
7.0
24
72
R05CA10
ATC
expectorants - combinations
4.4
6.8
17
40
J01DC02
ATC
cefuroxime; systemic
4.4
6.8
17
40
A07EC01
ATC
sulfasalazine; oral, rectal
4.4
6.8
17
40
L04AX01
ATC
azathioprine; systemic
40.8
6.8
8
*
R03AK08
ATC
formoterol and beclometasone; inhalant
7.4
6.8
15
21
4224
FHL
Endonasal anthrostomy
12.6
6.6
11
9
7860A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Dyspnoea and respiratory abnormalities[DYSPNOEA]
8.9
6.6
13
15
A03FA02
ATC
cisapride; oral, rectal
2.5
6.5
44
193
N06AA12
ATC
doxepin; systemic
2.8
6.4
32
120
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
5.7
6.4
17
31
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
7.2
6.3
14
20
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
7.2
6.3
14
20
L04AA13
ATC
[U] leflunomide
+∞
6.3
6
*
H02AB09
ATC
hydrocortisone; systemic
7.9
6.2
13
17
R01AD11
ATC
triamcinolone; nasal
3.1
6.1
26
89
N02AX02
ATC
tramadol; systemic, rectal
1.8
6.1
144
989
N05BB01
ATC
hydroxyzine; systemic
2.8
6.1
30
112

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
20
14
15.03
12.41
6.2
1.4
—
—
—
0
0
151
2015
0.57
6.21
6.1
5.4
6.29
6.12
mmol/l
0.55
136
1787
164
2132
0.58
5.99
29.1
15.6
—
—
—
0
0
27
103
2.75
5.28
4.7
1.6
10.11
10.54
g/l
0.24
27
85
158
2009
0.63
4.63
6.1
6.0
2.58
2.52
mmol/l
0.40
141
1796
35
163
2.27
4.54
3.5
2.5
118.43
125.07
g/l
0.97
35
158
13
27
4.95
4.54
5.7
2.9
—
—
—
0
0
22
83
2.76
4.41
2.5
1.5
1.37
1.66
g/l
0.26
22
66
170
2101
0.64
4.14
33.2
16.4
25.36
28.12
mg/l
0.48
151
1743
157
1962
0.65
3.93
8.5
7.0
41.77
40.63
mmol/mol
0.57
142
1794
47
261
1.92
3.87
5.0
3.4
7.38
7.38
ph
0.11
34
163
156
1945
0.66
3.81
5.4
5.1
4.61
4.45
mmol/l
1.33
140
1755
7
8
8.89
3.79
1.3
1.1
—
—
—
0
0
155
1929
0.66
3.70
5.4
5.0
1.54
1.48
mmol/l
0.79
137
1722
28
130
2.25
3.68
3.9
2.9
25.34
24.99
mmol/l
0.19
28
124
47
267
1.87
3.62
5.0
3.4
5.84
5.72
kpa
0.36
47
255
157
1936
0.67
3.48
6.5
5.3
1.95
2.03
mu/l
0.27
143
1717
149
1856
0.67
3.48
4.7
4.3
1.25
1.23
mmol/l
0.17
135
1635
40
222
1.90
3.31
3.0
1.3
—
—
—
0
0
8
15
5.43
3.20
4.2
1.0
—
—
—
0
0
8
15
5.43
3.20
4.3
1.0
—
—
—
0
0
8
15
5.43
3.20
4.3
1.0
—
—
—
0
0
8
15
5.43
3.20
4.3
1.0
—
—
—
0
0
41
234
1.85
3.12
4.1
2.7
4.09
4.15
kpa
0.08
41
223
58
371
1.67
2.99
7.9
2.9
—
—
—
0
0
5
6
8.43
2.75
3.4
3.2
75.10
56.17
%
—
5
6
29
154
1.96
2.75
5.5
2.5
1.71
0.53
%
0.61
12
39
13
48
2.77
2.74
1.2
1.1
—
—
—
0
0
6
10
6.08
2.71
1.2
1.0
—
—
—
0
0
50
753
0.61
2.69
2.9
3.2
5.65
6.70
mmol/l
1.45
43
618
40
238
1.76
2.68
2.6
1.7
—
—
—
0
0
25
130
1.99
2.52
2.6
1.4
—
—
—
0
0
19
89
2.20
2.49
7.6
4.6
—
—
—
0
0
20
97
2.12
2.42
3.6
2.7
—
—
—
0
0
12
46
2.66
2.38
1.0
1.1
—
—
—
0
0
26
142
1.89
2.30
7.3
3.1
—
—
—
0
0
53
753
0.65
2.17
2.8
3.2
34.80
47.77
mg/l
0.32
33
490
27
153
1.83
2.14
5.8
2.5
0.00
0.11
%
—
10
38
25
142
1.82
1.98
5.3
2.5
3.25
0.56
%
—
8
36
26
157
1.71
1.71
5.8
2.6
0.00
0.32
%
—
9
37
6
19
3.19
1.66
1.0
1.2
—
—
—
0
0
7
25
2.83
1.65
2.3
2.0
4.91
5.10
e9/l
—
7
25
41
282
1.51
1.61
10.8
5.2
1.77
1.03
mmol/l
0.47
35
225
139
1607
0.78
1.47
5.0
4.2
15.34
15.11
pmol/l
0.44
123
1407
5
16
3.15
1.44
1.4
1.1
—
—
—
0
0
45
324
1.44
1.43
2.8
2.0
—
—
—
0
0
137
1582
0.79
1.42
7.4
5.3
201.00
4031.93
e6/l
—
7
42
18
292
0.60
1.33
1.8
1.4
—
—
—
0
0
6
24
2.52
1.31
1.3
1.8
—
—
—
0
0
27
178
1.56
1.30
4.1
4.1
88.47
95.39
ng/l
0.14
22
151
39
279
1.45
1.29
11.2
5.3
7.44
7.42
ph
0.87
24
164
22
139
1.62
1.26
2.2
1.4
—
—
—
0
0
83
674
1.30
1.26
2.7
2.2
3.25
3.19
mg/l
0.08
71
572
62
780
0.75
1.23
3.0
3.9
6.99
8.74
mg/mmol
0.14
42
481
20
124
1.65
1.23
2.3
1.3
—
—
—
0
0
61
768
0.75
1.22
1.9
1.9
1.22
1.26
mmol/l
0.16
51
615
8
39
2.07
1.16
2.4
1.8
58.63
59.60
%
—
8
39
35
251
1.44
1.16
1.2
1.3
—
—
—
0
0
29
201
1.48
1.14
13.6
6.4
—
—
—
0
0
119
1024
1.24
1.12
9.6
3.2
1.79
1.85
e9/l
0.21
109
869
9
163
0.54
1.11
2.0
1.5
—
—
—
0
0
5
21
2.40
1.09
1.2
1.0
—
—
—
0
0
24
162
1.52
1.07
2.2
1.5
—
—
—
0
0
116
1003
1.23
1.04
9.3
3.1
0.67
0.59
e9/l
2.44
106
817
119
1032
1.23
1.03
9.7
3.2
0.19
0.19
e9/l
0.07
111
860
109
941
1.23
0.99
10.4
3.3
24.24
26.17
%
1.05
104
877
79
660
1.25
0.96
8.6
2.9
—
—
—
0
0
116
1011
1.22
0.95
9.3
3.1
0.04
0.04
e9/l
0.09
107
822
6
28
2.16
0.92
1.3
1.3
0.77
0.91
g/l
—
6
28
40
510
0.76
0.89
4.8
3.4
308.39
186.31
ng/l
0.17
33
434
70
832
0.80
0.88
3.0
2.4
—
—
—
0
0
8
43
1.88
0.88
2.0
1.7
29.38
34.58
umol/l
—
8
36
6
30
2.02
0.87
2.5
2.0
1.00
2.83
u/field
—
6
12
106
927
1.20
0.84
10.1
3.2
8.99
9.12
%
0.20
100
853
26
189
1.40
0.83
1.3
1.2
373.33
479.05
titre
—
6
42
106
929
1.20
0.82
10.1
3.2
0.53
0.63
%
1.27
101
849
54
442
1.26
0.79
1.9
1.5
1.65
1.49
mg/l
0.10
43
360
67
789
0.82
0.78
2.0
1.8
29.73
20.40
nmol/l
0.83
59
655
98
1110
0.84
0.75
8.1
3.9
33.83
34.49
g/l
0.57
92
1020
43
345
1.28
0.75
11.0
5.2
104.12
104.52
mmol/l
0.15
43
345
5
24
2.10
0.75
1.0
1.3
—
—
—
0
0
105
927
1.19
0.74
10.1
3.2
2.67
2.79
%
0.19
100
851
7
38
1.86
0.74
2.0
1.1
0.72
0.79
nmol/l
—
7
30
7
40
1.76
0.71
6.1
2.6
12.41
10.46
pmol/l
—
7
40
5
27
1.86
0.68
1.4
1.3
1.72
1.61
g/l
—
5
27
157
1701
0.87
0.68
10.9
6.4
81.50
85.03
u/l
0.28
151
1565
20
146
1.39
0.65
15.5
6.6
0.77
0.67
%
0.54
20
146
99
883
1.17
0.62
4.5
3.6
—
—
—
0
0
78
881
0.85
0.58
5.5
3.0
2.36
2.36
mmol/l
0.03
71
784
111
1221
0.87
0.58
6.7
4.3
0.00
6.61
estimate
0.50
23
284
82
919
0.86
0.55
6.0
3.9
79.91
229.63
e6/l
1.04
68
669
6
38
1.59
0.54
1.3
1.2
—
—
—
0
0
16
215
0.73
0.54
1.5
1.2
—
—
—
0
0
9
62
1.46
0.53
2.7
3.4
—
—
—
0
0
9
134
0.66
0.52
2.9
1.9
—
—
—
0
0
20
153
1.32
0.51
15.3
6.4
1.43
1.35
%
0.21
20
153
26
207
1.28
0.51
2.5
2.7
4.22
5.32
e9/l
0.41
21
178
69
778
0.86
0.50
6.3
3.4
7.40
7.40
ph
0.50
57
554
34
407
0.82
0.49
1.4
1.2
1.87
1.24
u/ml
—
6
107
111
1207
0.88
0.48
6.7
4.2
0.00
0.00
estimate
-0.00
23
268
124
1144
1.13
0.48
12.2
6.5
4.79
4.15
e9/l
1.80
118
963
83
747
1.14
0.47
6.4
3.9
—
—
—
0
0
113
1225
0.89
0.46
6.7
4.2
0.19
1.15
estimate
0.39
21
263
14
186
0.74
0.45
5.0
4.2
—
—
—
0
0
7
50
1.41
0.45
1.0
1.1
—
—
—
0
0
109
1180
0.89
0.44
3.6
2.9
42.73
56.16
u/l
1.19
100
1080
76
840
0.88
0.42
5.0
3.4
31.20
158.44
e6/l
0.97
66
651
104
958
1.12
0.41
5.8
3.8
6.57
6.31
ph
1.79
67
526
0
15
0.00
0.41
0.0
2.5
—
6.99
—
0
9
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
—
—
0
0
87
951
0.89
0.41
7.1
4.4
0.00
0.06
estimate
1.41
20
216
0
17
0.00
0.40
0.0
2.7
—
—
—
0
0
38
326
1.18
0.40
2.2
1.3
1.81
2.68
g/l
2.07
30
163
104
1122
0.90
0.39
2.4
2.2
99.69
95.32
pmol/l
0.35
50
569
0
19
0.00
0.39
0.0
1.3
—
72.23
—
0
13
116
1242
0.90
0.38
15.9
18.9
1.26
1.38
inr
1.41
92
1060
9
70
1.29
0.37
1.1
1.1
—
—
—
0
0
24
199
1.22
0.36
1.7
1.4
81.83
107.51
ug/g
0.44
18
152
65
714
0.89
0.34
4.8
3.3
0.30
0.53
e6/l
0.90
55
532
88
950
0.90
0.33
16.9
10.5
0.00
0.00
e9/l
1.21
77
764
6
87
0.68
0.33
1.0
1.4
—
28.60
—
0
8
10
75
1.34
0.30
8.4
3.4
3.72
3.93
mmol/l
—
10
75
8
107
0.74
0.29
2.1
2.6
—
16.70
—
0
5
51
562
0.89
0.28
6.3
4.5
1.02
1.02
kg/l
0.06
34
370
24
206
1.18
0.27
2.7
2.9
148.58
241.80
ng/l
0.82
24
190
26
226
1.16
0.25
2.0
2.0
80.03
63.12
e9/l
1.27
18
167
9
77
1.17
0.24
1.4
1.3
—
—
—
0
0
68
729
0.92
0.23
6.0
4.2
0.00
0.00
estimate
-0.00
19
231
106
1115
0.93
0.23
12.0
5.0
1.21
1.21
mmol/l
0.38
99
1003
5
40
1.25
0.22
2.2
1.6
—
—
—
0
0
68
635
1.09
0.22
8.6
5.4
—
—
—
0
0
5
41
1.22
0.22
1.2
1.0
—
106.00
—
0
5
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
58.83
—
0
6
0
10
0.00
0.21
0.0
1.2
—
8.29
—
0
10
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
62
660
0.93
0.18
7.9
3.8
0.00
0.17
estimate
0.74
19
195
121
1257
0.94
0.18
11.8
5.3
1.22
1.21
mmol/l
0.21
105
1052
98
1022
0.94
0.16
5.7
4.4
158.32
77.52
ng/l
0.30
79
821
18
203
0.88
0.15
4.7
3.3
6.67
6.09
ph
1.14
12
147
58
612
0.94
0.14
3.4
3.7
—
—
—
0
0
18
160
1.13
0.14
1.4
1.4
—
—
—
0
0
74
707
1.06
0.14
3.3
2.2
—
—
—
0
0
98
945
1.05
0.13
4.6
2.9
108.97
133.29
ug/l
1.06
91
849
9
110
0.81
0.13
1.3
1.3
—
—
—
0
0
56
533
1.06
0.12
4.9
3.1
547.76
529.31
mosm/kgh2o
0.27
50
465
54
567
0.94
0.12
2.0
1.9
498.84
456.90
pmol/l
0.43
43
451
37
393
0.93
0.11
4.8
3.3
4.00
2.99
e6/l
0.22
23
200
14
155
0.90
0.09
1.6
1.5
—
—
—
0
0
11
97
1.14
0.09
7.7
3.7
1.52
1.38
mmol/l
0.18
11
97
7
67
1.05
0.08
1.9
1.1
—
—
—
0
0
6
73
0.82
0.07
1.2
1.4
—
—
—
0
0
47
489
0.96
0.07
1.1
1.3
—
—
—
0
0
56
542
1.04
0.07
2.0
1.8
1211.98
1185.65
nmol/l
0.07
41
408
28
294
0.95
0.06
1.3
1.2
25.31
20.67
iu/ml
—
7
92
19
201
0.94
0.04
9.6
3.6
7.39
7.35
ph
1.40
14
127
10
109
0.92
0.04
1.5
3.0
—
—
—
0
0
10
109
0.92
0.04
1.6
1.3
—
—
—
0
0
20
210
0.95
0.03
2.1
2.1
0.00
0.07
estimate
—
5
41
99
982
1.01
0.01
4.2
2.6
—
—
estimate
—
0
0
120
1207
0.99
0.01
8.4
5.3
9.68
12.26
umol/l
2.08
115
1138
25
256
0.97
0.00
1.2
1.2
1.14
2.36
u/ml
—
10
79
59
584
1.01
0.00
7.0
3.4
0.00
0.03
—
6
30
38
378
1.01
0.00
2.8
1.6
28.45
29.53
s
0.70
38
368
15
147
1.02
0.00
1.1
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
156.07
—
0
9
8
79
1.01
-0.00
1.5
1.6
31.25
58.71
mg/l
—
8
68
8
79
1.01
-0.00
1.5
1.6
27.09
124.38
mg/l
—
8
68
0
7
0.00
-0.00
0.0
1.3
—
6.84
—
0
7
0
5
0.00
-0.00
0.0
3.8
—
2.30
—
0
5
7
71
0.99
-0.00
7.6
11.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
0.64
—
0
5
13
130
1.00
-0.00
3.5
2.5
—
—
—
0
0
5
51
0.98
-0.00
1.4
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
80.88
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
16.42
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
8.85
—
0
6
8
88
0.91
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
66
0.91
-0.00
1.7
1.5
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ILD_ASETYLCYSTEINE – ILD medications: acetylcysteine

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).