Hip and thigh

Z21_HIP_THIGH

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — ZA5.1 Cause of death: ICD-10 — ZA5.1 2 out of 7 registries used, show all original rules.	107
4. Check minimum number of events None	107
5. Include endpoints None	107
6. Filter based on genotype QC (FinnGen only)	92

Control definitions (FinnGen only)

Control exclude: Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: Z[AB]

NAME	Z21_HIP_THIGH
CONTROL_EXCLUDE	Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	ZA51
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	ZA51
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Hip and thigh based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	92	60	32
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	64.33	60.30	71.89

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
98: Matched controls
980

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

ZA5.1

ICD-10 Finland

Hip and thigh

+∞

134.6

NF1AA

NOMESCO Finland

Hip X-ray examination

9.4

21.4

M16.1

ICD-10 Finland

Other primary coxarthrosis

6.0

13.7

M16.0

ICD-10 Finland

Primary coxarthrosis, bilateral

6.6

13.3

L13

ICPC

Hip symptom/complaint

4.7

12.2

131

NF1AE

NOMESCO Finland

Hip joint ultrasound examination

27.0

9.2

NE1AA

NOMESCO Finland

Pelvis X-ray examination

5.2

7.8

A09

ICD-10 Finland

Other gastroenteritis and colitis of infectious and unspecified origin

3.7

7.8

108

NE1AD

NOMESCO Finland

Pelvis and hip bones CT examination

15.0

7.6

M79.6

ICD-10 Finland

Pain in limb

3.3

7.4

347

NFB30

NOMESCO Finland

Primary total prosthetic replacement of hip joint not using cement

6.4

7.0

N02AX02

ATC

tramadol; systemic, rectal

3.1

6.9

306

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3000475) Leukocytes [#/volume] in Synovial fluid

8.37

5.83

1.5

1.1

6790.80

9219.11

e6/l

—

(3044941) Cell count panel - Synovial fluid

9.96

5.43

1.3

1.1

—

(3042936) Bacteria identified in Isolate by Culture

131

2.72

4.49

2.4

2.0

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

174

2.57

4.49

6.4

3.9

23.21

282.96

ng/l

1.01

141

(3023368) Bacteria identified in Blood by Culture

236

2.46

4.47

5.4

4.5

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

155

2.46

3.86

1.3

24.44

3.74

u/ml

—

(3021788) Differential panel - Synovial fluid

7.14

3.75

1.3

1.1

—

(3019977) pH of Arterial blood

109

2.59

3.62

9.5

6.8

7.42

7.43

0.05

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

399

2.20

3.52

3.5

2.6

—

estimate

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

5.39

3.46

2.2

1.4

—

(3003396) Base excess in Arterial blood by calculation

112

2.51

3.42

9.3

6.7

1.91

1.58

mmol/l

0.15

(3001604) Monocytes [#/volume] in Blood

454

2.18

3.30

10.1

6.4

0.59

e9/l

0.04

388

(3006315) Basophils [#/volume] in Blood

456

2.16

3.24

10.2

6.4

0.04

e9/l

0.92

388

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

7.89

3.10

1.2

1.1

—

(3018095) Leukocytes [#/volume] in Urine

348

2.05

3.04

4.9

4.3

62.71

61.94

e6/l

0.01

257

(3015171) Extractable nuclear Ab [Units/volume] in Serum

3.74

3.01

1.3

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

112

2.38

2.97

2.3

2.0

—

(3002582) Erythrocytes [#/volume] in Urine

315

2.03

2.94

4.0

3.5

31.97

242.19

e6/l

0.54

249

(3019198) Lymphocytes [#/volume] in Blood

466

2.08

2.93

10.2

6.4

1.85

1.83

e9/l

0.10

409

(42870588) Differential panel, method unspecified - Blood

298

2.02

2.91

12.5

6.6

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

509

2.10

2.86

14.2

10.0

3.87

4.22

e9/l

0.70

442

(3048689) Calprotectin [Mass/mass] in Stool

107

2.36

2.85

1.5

2.3

76.60

163.73

ug/g

1.02

(3007853) Bacteria identified in Skin by Aerobe culture

109

2.31

2.73

1.2

1.9

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

194

2.06

2.69

2.8

2.6

0.99

1.06

mg/l

0.10

159

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

118

2.24

2.63

2.4

1.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

602

2.17

2.63

6.4

5.0

—

(3016018) Differential panel - Cerebral spinal fluid

7.45

2.58

1.8

1.0

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

401

1.93

2.56

3.2

103.17

112.40

ug/l

0.25

381

(3013115) Eosinophils [#/volume] in Blood

470

1.95

2.53

11.7

6.8

0.25

0.18

e9/l

0.70

407

(3026493) Urate [Moles/volume] in Serum or Plasma

223

1.97

2.52

3.0

3.3

355.39

339.04

umol/l

0.25

197

(3003327) Ova and parasites identified in Stool by Light microscopy

3.43

2.37

1.3

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

3.43

2.37

1.4

—

(3018010) Neutrophils/Leukocytes in Blood

423

1.83

2.21

11.2

6.1

55.29

57.87

1.00

398

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.39

2.18

1.2

1.7

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

191

1.91

2.16

2.9

2.3

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

167

1.95

2.15

1.4

1.3

82.71

32.67

iu/ml

—

(3035350) Ketones [Presence] in Urine by Test strip

488

1.81

2.07

4.3

0.00

16.24

estimate

0.50

100

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.49

1.96

1.8

1.7

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

4.72

1.96

1.4

—

(3023410) Appearance of Cerebral spinal fluid

4.72

1.96

3.0

1.2

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

662

2.00

1.96

5.1

4.4

14.58

14.94

pmol/l

0.63

605

(3009261) Glucose [Presence] in Urine by Test strip

494

1.77

1.92

4.3

0.00

estimate

-0.00

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

3.34

1.92

2.4

1.0

10.43

2.80

e6/l

—

(3019150) Specific gravity of Urine by Refractometry

215

1.81

1.91

3.4

4.5

1.02

kg/l

0.18

145

(3013826) Glucose [Moles/volume] in Serum or Plasma

516

1.77

1.88

8.0

5.4

6.81

6.68

mmol/l

0.19

486

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

2.17

1.87

1.4

1.7

—

(3044290) Cell count panel - Cerebral spinal fluid

3.69

1.87

2.7

1.1

—

(3030467) Casts [#/volume] in Urine by Automated count

269

1.75

1.86

4.3

3.4

0.55

0.35

e6/l

0.20

202

(3018418) pH of Serum or Plasma

278

1.74

1.86

5.4

4.7

7.39

7.40

0.35

205

(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid

3.20

1.83

2.4

1.1

1252.14

279.12

e6/l

—

(40758558) Short blood count panel - Blood

289

1.72

1.80

10.3

7.2

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

3.06

1.76

2.0

1.6

0.23

0.21

g/l

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

3.06

1.76

2.0

1.7

1.24

1.17

g/l

—

(3026008) Bacteria identified in Urine by Culture

282

1.71

1.75

4.2

3.3

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

154

1.84

1.72

2.3

2.0

—

(3021601) Nitrite [Presence] in Urine by Test strip

483

1.70

1.72

4.3

0.00

estimate

-0.00

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

231

1.72

1.69

2.2

2.33

2.70

mg/l

0.45

208

(3037522) Nuclear Ab [Titer] in Serum

115

1.93

1.68

1.6

1.5

168.00

826.67

titre

—

(36304419) Bacteria [Presence] in Urine

259

1.69

1.64

4.4

3.1

—

estimate

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

225

1.70

1.61

3.6

3.9

—

0.00

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

519

1.67

1.59

3.7

3.2

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.22

1.57

11.1

8.8

95.17

94.05

0.82

(3014051) Protein [Presence] in Urine by Test strip

271

1.66

1.56

2.9

3.7

—

0.00

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

2.97

1.53

1.5

1.3

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.36

1.52

1.3

1.4

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

152

1.77

1.50

3.9

3.4

2.50

1.93

e6/l

0.20

(3015736) pH of Urine

388

1.59

1.43

3.3

4.0

6.57

6.26

1.16

220

(3012095) Magnesium [Moles/volume] in Serum or Plasma

154

1.74

1.43

5.5

5.1

0.76

0.80

mmol/l

0.95

141

(46236952) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)/1.73 sq M

2.05

1.41

2.7

3.0

87.80

58.35

ml/min/173m2

—

(3003694) ABO and Rh group [Type] in Blood

225

1.63

1.37

1.3

1.4

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

141

1.72

1.32

3.4

3.2

19.45

21.26

0.33

134

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

2.03

1.29

16.0

4.2

25.08

24.29

mmol/l

0.51

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.49

1.26

1.3

1.2

—

(3044640) Blood type and Crossmatch panel - Blood

275

1.55

1.24

3.1

2.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

369

1.53

1.23

4.2

4.3

0.00

0.01

estimate

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

2.39

1.20

1.3

3.2

0.00

g/l

—

(3019230) Fractional oxyhemoglobin in Venous blood

2.58

1.16

6.8

2.1

69.00

58.15

—

(3037756) Immunofixation for Serum or Plasma

2.45

1.10

1.0

2.0

—

(3000991) Gas panel - Venous blood

1.80

1.08

20.7

8.7

—

(3019060) Gas panel - Arterial blood

1.94

1.08

4.0

4.1

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.87

1.06

1.5

1.4

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

167

1.58

1.05

4.0

3.2

0.66

0.93

e6/l

0.35

(4024509) Urine culture

1.96

1.04

1.7

2.1

—

(40768797) Stomach Pathology biopsy report

117

1.66

1.03

1.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.84

1.02

21.2

10.9

25.92

25.05

mmol/l

0.41

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.84

0.97

6.0

4.2

4.96

4.44

pmol/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

394

1.43

0.94

2.5

2.2

96.17

94.94

pmol/l

0.08

207

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.68

0.94

3.1

2.0

277.47

393.93

nmol/l

0.95

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.22

0.93

1.3

1.4

—

(42529406) Shigella sp [Presence] in Stool by Culture

2.22

0.93

1.0

1.2

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

2.22

0.93

1.0

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.22

0.93

1.0

1.2

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

2.14

0.91

1.3

1.7

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.94

0.90

1.5

1.3

—

(1002224) Polysomnography panel

2.06

0.88

1.0

1.1

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.89

0.88

2.0

2.8

—

(3012516) Albumin [Mass/volume] in Urine

275

1.42

0.86

4.7

3.4

37.04

72.90

mg/l

0.80

187

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.87

0.80

1.0

1.3

—

(3005322) IgE [Units/volume] in Serum or Plasma

1.72

0.79

2.5

1.2

1300.02

357.42

u/ml

0.32

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

2.23

0.77

1.0

1.5

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

2.23

0.77

1.0

1.5

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

2.14

0.75

1.4

1.2

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.81

0.73

2.3

2.1

—

(3012544) pH of Venous blood

102

1.56

0.73

13.2

4.2

7.38

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.51

0.71

2.8

3.4

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.72

0.70

1.1

1.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.68

0.68

1.5

3.3

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

1.83

0.67

1.6

1.3

—

3.34

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

1.83

0.67

1.6

1.4

—

2.77

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.83

0.67

1.2

2.0

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.64

0.66

1.0

1.1

—

(3020682) Albumin/Creatinine [Ratio] in Urine

286

1.35

0.66

4.9

4.0

4.28

11.51

mg/mmol

1.69

184

(3022313) Gas panel - Capillary blood

1.65

0.63

5.3

10.0

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.70

0.62

1.0

1.2

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.61

0.0

3.0

—

8.67

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.61

0.0

3.0

—

4.97

—

(3012501) Base excess in Blood by calculation

0.00

0.61

0.0

3.0

—

2.22

—

(4034850) Laboratory test

0.00

0.61

0.0

14.8

—

(3023520) Reticulocytes [#/volume] in Blood

1.55

0.60

1.8

3.9

82.43

69.52

e9/l

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.60

0.0

1.5

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.58

0.57

1.6

2.0

0.75

1.29

g/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

360

1.29

0.56

3.2

4.5

26.02

35.87

ng/l

0.50

254

(42868678) Cholesterol non HDL [Moles/volume] in Serum or Plasma

1.52

0.56

1.4

1.9

3.57

3.65

mmol/l

—

(3027945) Reticulocytes/Erythrocytes in Blood

109

1.44

0.55

3.8

3.9

2.04

1.80

0.71

101

(3029937) Albumin [Presence] in Urine by Test strip

266

1.30

0.53

4.8

3.9

0.00

estimate

-0.00

(3005719) IgG [Mass/volume] in Serum or Plasma

1.42

0.52

2.4

3.7

9.33

9.63

g/l

—

(3007164) IgA [Mass/volume] in Serum or Plasma

201

1.33

0.52

1.5

1.4

2.34

2.30

g/l

0.04

115

(3021589) Normoblasts [#/volume] in Blood

395

1.26

0.48

17.7

12.0

0.00

e9/l

0.50

324

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.46

0.47

1.4

2.1

—

(40760892) CBC W Ordered Manual Differential panel - Blood

204

1.30

0.47

4.6

4.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

167

1.33

0.47

1.8

1.9

—

(1761868) Lipid panel - Serum or Plasma

330

0.79

0.44

2.7

3.4

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

132

1.35

0.44

8.5

6.3

103.53

103.69

mmol/l

0.05

132

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

1.59

0.43

1.6

1.4

—

(3049717) Cytology report of Urine Cyto stain

1.59

0.43

2.2

3.1

—

(3008898) HLA-B27 [Presence]

1.54

0.42

1.0

1.1

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

1.54

0.42

1.6

1.2

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

1.54

0.42

18.8

5.3

1.47

1.60

mg/l

—

(3003888) Timothy IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.1

—

1.88

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.41

0.0

2.1

—

1.59

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.41

0.0

2.9

—

31.87

—

(40767503) Oxygen content in Capillary blood by calculation

0.00

0.41

0.0

2.9

—

16.13

—

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

0.00

0.40

0.0

1.2

—

0.69

—

(3041096) Erythrocytes [Presence] in Urine by Automated

275

1.24

0.40

4.2

3.9

0.00

0.01

estimate

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.39

0.0

1.5

—

(1616796) Gas panel - Central venous blood

0.00

0.39

0.0

3.2

—

(3009343) pH of Capillary blood

1.31

0.38

5.1

8.2

7.43

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.29

0.37

5.1

8.1

5.28

5.05

kpa

—

(3000494) Fungus identified in Specimen by Culture

109

1.33

0.36

1.6

1.5

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

223

1.23

0.33

1.2

1.3

0.61

1.08

u/ml

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

195

1.23

0.32

5.3

5.2

22.21

22.63

0.05

105

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

130

1.28

0.31

1.6

1.7

—

(3022145) Colonoscopy Study observation

109

0.71

0.31

1.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.32

0.29

4.5

8.9

—

(40761511) CBC panel - Blood by Automated count

864

1.33

0.29

20.7

15.1

—

(40761535) Cells panel - Urine sediment

1.27

0.28

3.0

3.8

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

106

1.26

0.24

1.7

1.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.75

0.23

2.0

2.3

—

(40768443) Skin Pathology biopsy report

1.30

0.23

1.4

1.2

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

145

1.21

0.22

1.6

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.2

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.21

0.0

2.3

—

90.78

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(40760848) Basement membrane zone BP180 Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.21

0.0

1.3

—

7.84

—

(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.0

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.21

0.0

1.3

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.2

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.21

0.0

3.7

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.2

—

(3023430) Cat dander IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

0.79

—

(3014133) Dog dander IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

0.62

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.21

0.0

4.3

—

(3010726) Horse dander IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

0.06

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

156

1.19

0.20

1.5

1.6

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.20

0.0

2.8

—

108.36

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.20

0.0

2.8

—

3.92

—

(3008401) Mugwort IgE Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

1.56

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.20

0.0

2.8

—

1.19

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

295

1.13

0.17

2.8

4.4

838.34

1267.69

ng/l

0.92

258

(21494755) Public health laboratory ask at order entry panel

1.12

0.16

1.0

1.4

—

(40761536) Microorganisms panel - Urine sediment

0.79

0.16

3.0

3.7

—

(36660697) Celiac disease serology panel - Serum

1.15

0.16

1.2

1.1

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

805

0.90

0.09

23.9

16.1

78.83

79.23

ml/min/173m2

0.06

757

(3025941) Bacteria identified in Stool by Culture

1.14

0.09

1.5

1.2

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.12

0.08

2.6

4.4

1.26

1.23

mmol/l

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.08

0.07

1.6

2.1

3.31

3.43

ratio

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.03

0.07

1.6

1.8

—

(3002256) Pathology report gross observation

104

0.85

0.06

1.7

1.2

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.12

0.05

1.1

1.6

—

(40768804) Tissue Pathology biopsy report

352

0.99

0.00

2.4

2.1

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

0.0

1.0

—

(4146454) Self-monitoring of blood glucose

0.00

0.0

3.5

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

0.0

2.6

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.0

1.0

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

0.92

0.00

6.8

2.5

1.28

0.95

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.00

0.00

1.2

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

23.93

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

0.94

0.00

6.8

2.5

0.50

0.66

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

94.67

—

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

-0.00

0.0

1.6

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

0.91

-0.00

1.9

1.3

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.7

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

8.28

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

9.3

—

0.64

—

(44806420) Estimation of glomerular filtration rate

0.00

-0.00

0.0

2.1

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.3

—

4.64

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.7

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

1.2

—

15.60

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

0.61

—

(3034988) Calcium [Moles/volume] in Capillary blood

0.00

-0.00

0.0

3.5

—

1.19

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.7

—

(3036603) Volume of Urine

0.00

-0.00

0.0

1.3

—

1429.29

—

(3047189) Immunofixation for 24 hour Urine

0.00

-0.00

0.0

1.8

—

(3004451) EKG impression Narrative

0.00

-0.00

0.0

1.3

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.2

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.8

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

0.86

-0.00

3.7

2.1

12.98

13.58

nmol/l

—

(4211845) Urine protein measurement

0.00

-0.00

0.0

1.0

—

(3020911) Cortisol [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.0

—

50.33

—

(4035726) Immunohistochemistry procedure

0.97

-0.00

1.6

1.3

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

5.2

—

369.00

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

10.4

—

1370.00

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.99

-0.00

1.6

2.2

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

8.4

—

814.20

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3000492) Spirometry study

0.89

-0.00

1.6

1.8

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.3

—

10.41

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.5

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.3

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: Z21_HIP_THIGH – Hip and thigh

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R14

FinnGen R13 + FinRegistry

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Hip and thigh

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Hip and thigh (Z21_HIP_THIGH)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints