Other fusion of spine

M13_SPINEFUSION

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M43.2 Cause of death: ICD-10 — M43.2 2 out of 7 registries used, show all original rules.	73
4. Check minimum number of events None	73
5. Include endpoints None	73
6. Filter based on genotype QC (FinnGen only)	64

Control definitions (FinnGen only)

Control exclude: M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M43
Name in latin: Alia fusio columnae vertebralis

NAME	M13_SPINEFUSION
CONTROL_EXCLUDE	M13_DORSOPATHY
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M432
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M432
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other fusion of spine based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	412	227	184
Only index persons	396	221	175
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	51.00	53.38	48.01
Only index persons	50.22	53.20	46.46

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	64	42	22
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	53.80	54.39	52.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
64: Matched controls
640

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M43.2

ICD-10 Finland

Other fusion of spine

+∞

91.9

M47.2

ICD-10 Finland

Other spondylosis with radiculopathy

+∞

25.8

NA3BG

NOMESCO Finland

Lumbar spine MRI examination with high intensity magnet

85.0

24.3

N03AX16

ATC

[U] pregabalin

13.1

24.3

M43.1

ICD-10 Finland

Spondylolisthesis

122.5

17.6

N03AX12

ATC

[U] gabapentin; oral

10.2

17.2

NA3AA

NOMESCO Finland

Lumbar spine X-ray examination without contrast

29.6

16.6

NA3EA

NOMESCO Finland

Lumbar spine X-ray examination with flexion

+∞

16.3

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

43.9

15.9

M54.5

ICD-10 Finland

Low back pain

7.9

15.8

100

NA3CG

NOMESCO Finland

Lumbar spine extensive MRI examination with high intensity magnet

192.1

15.2

M51.3

ICD-10 Finland

Other specified intervertebral disc degeneration

56.6

15.0

M54.4

ICD-10 Finland

Lumbago with sciatica

9.3

14.7

NAG62

NOMESCO Finland

Posterior fusion of lumbar spine with fixation, 2-3 vertebraea

+∞

14.1

N02AX02

ATC

tramadol; systemic, rectal

7.4

13.9

147

M43.0

ICD-10 Finland

Spondylolysis

+∞

11.8

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

13.0

11.7

L03

ICPC

Low back symptom/complaint

5.9

11.2

M47.80

ICD-10 Finland

Other spondylosis, multiple sites in spine

130.5

10.8

L01

ICPC

Neck symptom/complaint

6.6

10.1

NA1BG

NOMESCO Finland

Cervical spine MRI examination with high intensity magnet

43.5

9.4

M48.0

ICD-10 Finland

Spinal stenosis

32.6

8.8

M53.1

ICD-10 Finland

Cervicobrachial syndrome

10.6

8.8

ABC36

NOMESCO Finland

Decompression of lumbar nerve roots

+∞

8.5

NA3AD

NOMESCO Finland

Lumbar spine and sacrum CT examination

38.8

8.3

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

5.5

8.3

M01AB05

ATC

diclofenac; systemic, rectal

6.0

7.3

345

A01

ICPC

Pain general/multiple sites

7.8

7.0

SHA03

NOMESCO Finland

Stomatognathic treatment, demanding

25.7

6.9

M47.9

ICD-10 Finland

Spondylosis, unspecified

77.2

6.6

M53.2

ICD-10 Finland

Spinal instabilities

+∞

6.3

M01AH05

ATC

etoricoxib; oral

4.6

6.2

295

WX408

NOMESCO Finland

General anesthesy, balanced

3.9

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

161

2.63

3.46

2.5

2.1

154.33

187.27

u/l

0.26

153

(40768797) Stomach Pathology biopsy report

2.77

2.88

1.3

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

5.47

2.81

1.1

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

5.47

2.81

1.1

1.2

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

5.10

2.68

1.3

1.2

—

(3006315) Basophils [#/volume] in Blood

286

2.36

2.67

4.8

5.6

0.04

e9/l

0.25

253

(3001604) Monocytes [#/volume] in Blood

287

2.35

2.63

4.8

5.6

0.60

0.57

e9/l

0.35

252

(3013650) Neutrophils [#/volume] in Blood by Automated count

318

2.40

2.59

6.2

10.4

4.22

4.03

e9/l

0.23

276

(3025941) Bacteria identified in Stool by Culture

3.51

2.57

1.2

—

(3022621) pH of Urine by Test strip

2.98

2.53

3.0

2.1

6.07

—

(3030467) Casts [#/volume] in Urine by Automated count

141

2.27

2.44

3.3

2.6

0.19

0.55

e6/l

1.15

(3019198) Lymphocytes [#/volume] in Blood

293

2.26

2.43

4.8

5.6

2.06

1.74

e9/l

1.93

264

(3000991) Gas panel - Venous blood

3.57

2.41

8.3

7.3

—

(3031040) Bacteria [#/volume] in Urine by Automated count

356

2.39

2.37

7.7

3.9

—

96.13

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

3.44

2.33

1.4

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

3.44

2.33

8.3

6.9

1.30

1.45

mmol/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

222

2.13

2.27

2.4

2.0

97.73

98.88

pmol/l

0.05

107

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

187

2.14

2.26

3.2

2.8

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.36

2.15

3.4

2.3

0.48

1.39

e6/l

1.09

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.00

2.02

1.7

1.6

—

(3026008) Bacteria identified in Urine by Culture

169

2.03

1.95

5.4

2.9

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.39

1.93

6.0

5.7

102.57

104.82

mmol/l

0.70

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

129

2.07

1.88

1.6

1.5

0.70

1.42

mg/l

0.78

102

(3019150) Specific gravity of Urine by Refractometry

116

2.05

1.75

3.5

3.9

1.02

kg/l

0.17

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.37

1.70

10.8

8.7

24.87

25.05

mmol/l

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.89

1.63

11.9

8.5

16.07

15.69

—

(3021589) Normoblasts [#/volume] in Blood

242

1.86

1.62

6.1

11.3

0.00

e9/l

-0.00

196

(3000494) Fungus identified in Specimen by Culture

2.22

1.57

1.4

1.5

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

441

2.17

1.53

5.2

4.5

14.93

14.95

pmol/l

0.02

397

(40758558) Short blood count panel - Blood

165

1.85

1.48

4.0

5.6

—

(3015736) pH of Urine

229

1.79

1.46

3.3

3.6

6.22

6.19

0.04

122

(3009261) Glucose [Presence] in Urine by Test strip

297

1.80

1.43

4.5

3.9

0.00

estimate

—

(3035350) Ketones [Presence] in Urine by Test strip

298

1.79

1.41

4.5

3.8

0.00

estimate

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.77

1.40

12.0

9.3

95.58

95.31

—

(3018418) pH of Serum or Plasma

169

1.79

1.36

2.6

3.5

7.40

0.23

113

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.65

1.33

1.0

—

(3002582) Erythrocytes [#/volume] in Urine

170

1.77

1.33

3.6

2.9

8.46

56.09

e6/l

1.33

125

(3037522) Nuclear Ab [Titer] in Serum

1.95

1.29

1.3

1.4

—

512.86

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

256

1.70

1.24

2.7

108.84

105.35

ug/l

0.04

236

(3045414) Leukocytes [Presence] in Urine

2.19

1.24

4.0

2.4

—

0.00

estimate

—

(3042936) Bacteria identified in Isolate by Culture

1.93

1.21

1.5

1.9

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

122

1.79

1.20

3.1

1.9

—

(3021601) Nitrite [Presence] in Urine by Test strip

297

1.69

1.19

4.4

3.7

0.00

estimate

—

(40761535) Cells panel - Urine sediment

2.41

1.14

3.7

3.9

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.26

1.09

1.3

1.9

—

(3044640) Blood type and Crossmatch panel - Blood

170

1.66

1.07

3.1

2.1

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.97

1.06

1.9

1.6

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

2.38

1.05

14.2

7.7

24.40

24.93

mmol/l

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.97

1.04

1.7

1.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.84

1.01

3.7

2.3

0.00

4.69

e6/l

—

(3018095) Leukocytes [#/volume] in Urine

200

1.61

1.00

3.8

3.3

9.82

131.90

e6/l

1.73

133

(3023420) DNA double strand Ab [Units/volume] in Serum

2.34

0.96

1.2

1.3

—

5.25

—

(3003338) MCHC [Entitic Mass/volume] in Red Blood Cells

456

1.75

0.92

20.9

17.8

332.21

331.77

g/l

0.15

456

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

241

1.56

0.92

3.3

2.3

80.12

77.25

nmol/l

0.21

220

(42870588) Differential panel, method unspecified - Blood

186

1.56

0.89

5.4

5.2

—

(3023368) Bacteria identified in Blood by Culture

141

1.61

0.89

4.2

3.6

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.69

0.84

2.0

3.0

0.85

0.82

mmol/l

1.17

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

256

1.50

0.81

3.0

2.4

—

estimate

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.92

0.70

14.2

8.1

0.34

0.55

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.92

0.70

14.2

8.1

0.60

1.28

—

(1761868) Lipid panel - Serum or Plasma

247

0.67

0.69

3.7

3.3

—

(3029937) Albumin [Presence] in Urine by Test strip

162

1.44

0.61

4.7

3.8

0.00

estimate

—

(3014051) Protein [Presence] in Urine by Test strip

162

1.44

0.61

5.0

3.1

—

0.00

—

(3032080) INR in Blood by Coagulation assay

249

1.39

0.57

13.8

12.0

1.30

1.22

inr

0.30

202

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

174

1.40

0.55

2.2

2.5

72.45

83.16

u/l

0.16

162

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.59

0.54

2.7

1.6

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

1.45

0.47

12.0

8.1

117.57

119.20

g/l

—

(4035726) Immunohistochemistry procedure

1.45

0.47

1.0

1.4

—

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

0.42

0.0

4.5

—

4.03

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

0.41

0.0

2.3

—

54.11

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

530

1.45

0.41

4.8

4.3

1.23

1.25

mmol/l

0.15

478

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.42

0.41

4.4

6.5

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

117

1.37

0.40

1.5

1.3

41.35

26.46

iu/ml

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

108

1.38

0.39

1.3

1.5

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.41

0.39

1.5

1.8

12.32

12.53

umol/l

0.03

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.47

0.37

1.7

2.3

50.50

61.15

ng/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.40

0.35

2.8

1.7

—

(3027801) Oxygen [Partial pressure] in Arterial blood

1.42

0.33

12.0

7.8

12.40

11.97

kpa

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

1.42

0.33

12.0

7.8

4.93

4.99

kpa

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

345

1.25

0.32

2.5

2.7

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.31

0.31

1.6

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.36

0.30

1.7

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

1.37

0.30

1.2

1.9

20.58

20.97

—

(3007164) IgA [Mass/volume] in Serum or Plasma

114

1.29

0.28

1.1

1.4

2.52

2.68

g/l

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.25

0.27

2.0

3.5

1.01

1.06

mmol/l

—

(3003694) ABO and Rh group [Type] in Blood

167

0.79

0.25

1.6

1.4

—

(40760892) CBC W Ordered Manual Differential panel - Blood

136

1.24

0.23

3.4

5.6

—

(3013512) EKG study

204

1.20

0.22

2.9

3.6

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.6

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.3

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.9

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.6

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

5.59

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.21

0.0

3.0

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.9

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

292.37

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3016502) Oxygen saturation in Arterial blood

1.22

0.20

13.7

8.1

96.30

95.83

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

2.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.26

0.19

2.1

3.4

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

129

1.21

0.19

1.1

1.2

0.57

1.32

u/ml

—

(3000492) Spirometry study

1.21

0.19

1.1

1.5

—

(3012516) Albumin [Mass/volume] in Urine

188

1.17

0.18

3.8

3.0

11.97

46.23

mg/l

1.35

118

(3022145) Colonoscopy Study observation

1.22

0.17

1.1

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

218

1.16

0.17

4.4

4.1

11.50

51.78

ng/l

1.59

150

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

565

1.28

0.16

6.2

5.1

4.61

4.69

mmol/l

0.22

520

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.78

0.16

1.7

1.4

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

562

1.34

0.16

6.2

5.0

1.50

1.51

mmol/l

0.09

513

(3009508) Creatinine [Moles/volume] in Urine

191

1.15

0.14

3.9

3.0

9.83

8.13

mmol/l

0.59

159

(3020682) Albumin/Creatinine [Ratio] in Urine

193

1.13

0.12

4.5

3.6

0.75

7.96

mg/mmol

1.56

121

(40761536) Microorganisms panel - Urine sediment

1.09

0.10

6.2

3.7

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.07

0.09

1.8

1.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.05

0.09

1.6

1.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.12

0.09

1.3

1.4

—

(3003396) Base excess in Arterial blood by calculation

1.12

0.09

13.7

7.8

-0.07

1.66

mmol/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.10

0.09

1.7

1.8

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.16

0.08

1.6

1.8

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.12

0.04

1.7

1.5

—

(40768804) Tissue Pathology biopsy report

240

1.07

0.04

2.5

2.1

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

394

1.04

0.00

4.2

3.1

34.29

46.27

u/l

1.07

371

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.8

—

(40759850) Jo-1 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.5

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.0

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

12.8

—

2425.00

—

(3011288) Drugs identified in Urine by Screen method Nominal

0.00

-0.00

0.0

1.4

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.6

—

9.66

—

(3000012) Reticulocyte production index

0.00

-0.00

0.0

2.1

—

0.79

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.00

-0.00

1.7

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.2

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

44.90

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

9.8

—

1109.80

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

2.55

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

1.2

—

7.12

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3019309) Folate [Moles/volume] in Red Blood Cells

0.93

-0.00

1.9

1.6

783.43

1125.66

nmol/l

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

4.8

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

-0.00

0.0

1.4

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3003191) Choriogonadotropin [Presence] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(3019897) Erythrocyte [DistWidth] in Red Blood Cells by Automated count

0.00

-0.00

0.0

1.6

—

13.50

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

-0.00

0.0

1.4

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.8

—

(3004809) Band form neutrophils/Leukocytes in Blood

0.00

-0.00

0.0

3.5

—

1.00

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.4

—

(3017354) Segmented neutrophils/Leukocytes in Blood

0.00

-0.00

0.0

3.7

—

58.67

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.8

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

8.6

—

61.94

—

(3003129) Base excess in Capillary blood by calculation

0.00

-0.00

0.0

3.3

—

0.40

—

(44790049) Parainfluenza type 3 nucleic acid detection

0.00

-0.00

0.0

2.2

—

(44806118) Parainfluenza type 4 nucleic acid detection

0.00

-0.00

0.0

2.2

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.8

—

(44790048) Parainfluenza type 2 nucleic acid detection

0.00

-0.00

0.0

2.2

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3040151) Glucose [Moles/volume] in Capillary blood

0.00

-0.00

0.0

1.9

—

5.63

—

(3042631) Mycobacterium sp identified in Specimen

0.00

-0.00

0.0

1.7

—

(3045142) Bone marrow Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3002256) Pathology report gross observation

0.96

-0.00

1.1

1.2

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

203.33

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.8

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

3.4

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

2.1

—

31.43

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.3

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.6

—

4.54

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

2.6

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

-0.00

0.0

1.1

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.0

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

3.7

—

8.76

—

(44790047) Parainfluenza type 1 nucleic acid detection

0.00

-0.00

0.0

2.2

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_SPINEFUSION and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_SPINEFUSION.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: M13_SPINEFUSION – Other fusion of spine

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other fusion of spine

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints