suppurative otitis media: Inflammation of the middle ear with purulent discharge.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1152 |
4. Check minimum number of eventsNone |
1152 |
5. Include endpointsNone |
1152 |
6. Filter based on genotype QC (FinnGen only) |
1024 |
Control definitions (FinnGen only)
- Control exclude
- H8_MIDDLEMASTOID
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H66
- Name in latin
- Otitis media purulenta chronica non specificata
Similar endpoints
↥List of similar endpoints to
Suppurative otitis media, unspecified
based on the number of shared cases.
Similar with more cases:
- Suppurative and unspecified otitis media
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 14084 | 6111 | 7921 |
| Only index persons | 11984 | 5233 | 6751 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.20 | 0.18 | 0.22 |
| Only index persons | 0.23 | 0.19 | 0.26 |
| Median age at first event (years) | |||
| Whole population | 5.39 | 6.82 | 3.92 |
| Only index persons | 6.48 | 9.38 | 4.23 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1024 | 565 | 459 |
| Unadjusted period prevalence (%) | 0.21 | 0.20 | 0.21 |
| Median age at first event (years) | 34.23 | 25.40 | 45.10 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1068
- Matched controls
- 10672
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UDC00
NOMESCO Finland
Ear microscopy
14.1
309.4
331
330
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
838.2
307.7
677
22
4122
FHL
Tympanostomy (tympanic tube)
119.5
307.7
171
17
3829X
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified otitis media
+∞
282.1
258
*
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
488.9
208.0
201
5
4451
FHL
Guitar cutting
13.6
202.9
206
184
H66.0
ICD-10 Finland
Acute suppurative otitis media
9.1
201.2
291
422
H65.3
ICD-10 Finland
Chronic mucoid otitis media
271.0
200.1
199
9
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
42.6
194.4
118
31
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
417.1
177.0
173
5
H71
ICD-10 Finland
Cholesteatoma of middle ear
+∞
172.7
161
*
H66.9
ICD-10 Finland
Otitis media, unspecified
8.4
158.0
235
347
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
39.1
150.2
93
26
3824A
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified suppurative otitis media
+∞
146.2
137
*
DC1AD
NOMESCO Finland
Temporalbone CT
55.2
135.0
77
15
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
100.6
95
*
H65.2
ICD-10 Finland
Chronic serous otitis media
225.1
100.3
102
5
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
43.7
90.0
54
13
S02CA02
ATC
flumetasone and antiinfectives; otic
7.3
87.3
137
210
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
186.7
83.4
86
5
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.3
81.6
261
753
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
6.4
80.8
145
255
H60.9
ICD-10 Finland
Otitis externa, unspecified
5.1
79.0
190
437
H60.8
ICD-10 Finland
Other otitis externa
8.4
77.2
105
136
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
3.2
73.6
518
2454
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
72.7
69
*
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
13.9
72.1
68
52
DCD00
NOMESCO Finland
Myringoplasty
+∞
71.7
68
*
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
36.1
71.4
45
13
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
38.2
70.8
44
12
H65.0
ICD-10 Finland
Acute serous otitis media
15.1
70.3
63
44
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
66.3
63
*
DFF00
NOMESCO Finland
Pure tone audiometry
4.5
65.6
182
467
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
11.1
64.4
70
67
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
17.4
63.7
53
32
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
59.9
57
*
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
58.9
56
*
H74.1
ICD-10 Finland
Adhesive middle ear disease
554.5
54.0
53
*
Z97.4
ICD-10 Finland
Presence of external hearing-aid
5.9
53.0
100
183
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
3.3
51.9
234
831
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
11.6
50.5
53
48
H60.3
ICD-10 Finland
Other infective otitis externa
7.8
49.6
71
97
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
477.4
46.6
46
*
R4135
NOMESCO Finland
Rehabilitation for hearing problems
9.9
45.3
53
56
H04
ICPC
Ear discharge
6.2
44.3
78
133
1450
FHL
Otomicroscopy
16.6
43.6
37
23
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
16.6
43.6
37
23
4742A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Adenoid vegetations
6.4
41.7
71
117
4741B
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PHARYNGICAE]
8.1
41.5
57
74
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
40.9
39
*
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
138.3
38.0
40
*
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
37.7
36
*
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
+∞
37.7
36
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.3
37.7
639
4195
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
196.7
37.0
38
*
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
36.7
35
*
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
36.7
35
*
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
6.4
36.0
61
100
DAX08
NOMESCO Finland
Fitting of hearing aid
4.4
35.4
95
234
DFF15
NOMESCO Finland
Speech audiometry
4.7
35.3
85
192
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
4.5
34.8
89
211
Z3229
NOMESCO Finland
Other healthcare associate professional
3.5
34.5
127
392
TDA90
NOMESCO Finland
Removal wax from ear
10.1
33.1
38
39
4141
FHL
Myringoplasty (also for reasons other than inflammation)
+∞
31.4
30
*
H66
ICD-10 Finland
Suppurative and unspecified otitis media
5.0
29.5
65
136
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
11.8
29.2
30
26
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
5.3
28.8
59
116
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
28.2
27
*
J01DA01
ATC
[U] cefalexin
2.0
26.7
652
4659
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
+∞
26.1
25
*
J01DA08
ATC
[U] cefaclor
2.3
26.1
240
1191
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
8.0
25.6
35
45
H01
ICPC
Ear pain/earache
2.4
25.3
194
888
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
4.6
24.6
60
137
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
5.6
24.0
46
85
J01DA09
ATC
[U] cefadroxil
2.1
23.9
310
1756
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
23.0
22
*
DEB30
NOMESCO Finland
Radical mastoidectomy
234.7
22.7
23
*
DCD10
NOMESCO Finland
Tympanoplasty
+∞
21.9
21
*
H73.1
ICD-10 Finland
Chronic myringitis
+∞
21.9
21
*
R5120
NOMESCO Finland
Preparation of an aid
4.9
21.9
49
104
H61.2
ICD-10 Finland
Impacted cerumen
3.1
21.4
92
311
DGW00
NOMESCO Finland
Dilatation of eustachian tube
+∞
20.9
20
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
20.8
98
349
R01AD08
ATC
fluticasone; nasal
2.0
20.8
316
1880
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.1
20.7
89
301
J01MA02
ATC
ciprofloxacin; systemic
1.9
20.5
376
2378
H60.4
ICD-10 Finland
Cholesteatoma of external ear
42.5
20.5
25
6
J01CA04
ATC
amoxicillin; systemic
2.3
19.4
932
7957
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
56.0
19.0
22
*
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
18.8
18
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
18.6
137
612
R01AD09
ATC
mometasone; nasal
1.8
17.8
488
3450
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
+∞
17.7
17
*
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
+∞
17.7
17
*
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
17.7
17
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.0
17.0
211
1159
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.7
17.0
54
150
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
16.7
16
*
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
+∞
16.7
16
*
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
16.7
16
*
4660A
ICD-9 Finland
Acute bronchitis and bronchiolitis, Acute bronchitis
6.8
16.6
26
39
ZXA10
NOMESCO Finland
Bilateral
2.1
16.6
189
1006
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
91.5
16.6
18
*
4659X
ICD-9 Finland
Acute upper respiratory infections of multiple or unspecified sites, Unspecified site
5.7
16.1
30
54
J01DA06
ATC
[U] cefuroxime
2.2
15.9
156
783
H92.0
ICD-10 Finland
Otalgia
2.7
15.7
91
362
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
15.7
15
*
R01AD05
ATC
budesonide; nasal
2.7
15.6
86
333
J01DB01
ATC
cefalexin; oral
1.9
15.5
867
7380
R03AC02
ATC
salbutamol; inhalant
1.7
15.4
587
4479
H29
ICPC
Ear symptom/complaint other
2.2
15.2
145
720
H60.1
ICD-10 Finland
Cellulitis of external ear
6.4
15.0
25
40
J33.0
ICD-10 Finland
Polyp of nasal cavity
4.0
15.0
43
111
J01FF01
ATC
clindamycin; systemic
1.8
15.0
268
1656
EMB30
NOMESCO Finland
Adenotomy
3.6
14.7
49
141
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
14.6
14
*
R03BA05
ATC
fluticasone; inhalant
1.9
14.5
203
1158
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
151.9
14.5
15
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.5
13.8
89
373
4151
FHL
Reoperation for chronic otitis media
+∞
13.6
13
*
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
+∞
13.6
13
*
J45.1
ICD-10 Finland
Nonallergic asthma
2.5
13.5
86
358
DEB00
NOMESCO Finland
Cortical mastoidectomy
141.6
13.5
14
*
R03BA02
ATC
budesonide; inhalant
1.9
13.4
193
1109
R03DA04
ATC
theophylline; systemic, rectal
2.9
13.3
62
219
J01FA10
ATC
azithromycin; systemic
1.6
13.1
608
4796
H60
ICD-10 Finland
Otitis externa
2.6
12.9
74
292
H02AB07
ATC
prednisone; oral
2.1
12.7
126
635
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.2
12.5
113
548
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
5.1
12.4
26
52
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
12.2
192
1133
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.3
12.2
92
414
J01MA12
ATC
levofloxacin; systemic
1.9
12.1
163
916
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
9.4
12.0
24
26
H92.1
ICD-10 Finland
Otorrhoea
30.4
11.7
15
5
WX704
NOMESCO Finland
Intubation
2.3
11.6
87
390
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.0
11.5
141
765
DCA30
NOMESCO Finland
Exploration of middle ear
+∞
11.5
11
*
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.7
11.4
36
100
DFX03
NOMESCO Finland
Review, maintenance and user education for hearing aid
12.0
11.3
20
17
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.9
11.2
33
87
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
5.6
11.2
21
38
R03BC01
ATC
cromoglicic acid; inhalant
4.1
11.2
30
74
J32.4
ICD-10 Finland
Chronic pansinusitis
5.1
11.0
23
46
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.7
10.9
58
221
H71
ICPC
Acute otitis media/myringitis
4.5
10.8
26
59
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
60.6
10.6
12
*
DCW99
NOMESCO Finland
Other operation on eardrum and middle ear
111.0
10.4
11
*
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
10.4
10
*
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
10.4
10
*
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.0
10.3
45
154
R03AC12
ATC
salmeterol; inhalant
2.9
10.2
47
166
H02AB06
ATC
prednisolone; systemic
1.5
10.1
426
3221
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
3.4
10.1
35
104
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
9.9
212
1361
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
8.2
9.8
21
26
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.6
9.8
288
2002
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
55.5
9.7
11
*
DEE00
NOMESCO Finland
Osseous fixation of hearing aid
55.5
9.7
11
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.5
9.5
59
243
R03AC03
ATC
terbutaline; inhalant
1.9
9.5
131
740
4640A
ICD-9 Finland
Acute laryngitis and tracheitis, Acute laryngitis
3.9
9.4
27
70
J47
ICD-10 Finland
Bronchiectasis
4.3
9.4
24
57
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
+∞
9.4
9
*
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
9.4
9
*
H70.0
ICD-10 Finland
Acute mastoiditis
+∞
9.4
9
*
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
+∞
9.4
9
*
J01EB05
ATC
sulfafurazole; systemic
8.1
9.4
20
25
R02
ICPC
Shortness of breath/dyspnoea
1.8
9.3
136
783
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.5
9.1
55
224
J01FA01
ATC
erythromycin; systemic
1.7
9.0
180
1132
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
9.0
214
1410
ZXA05
NOMESCO Finland
Left side
1.7
9.0
198
1279
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
18.8
8.9
13
7
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.4
8.9
32
97
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
8.9
233
1572
J46
ICD-10 Finland
Status asthmaticus
3.5
8.8
30
88
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
8.8
199
1295
R06AE07
ATC
cetirizine; oral
1.5
8.8
435
3375
7803A
ICD-9 Finland
General symptoms, Convulsions
3.9
8.7
25
65
S02AA30
ATC
antiinfectives, combinations; otic
2.0
8.7
93
481
R03CC03
ATC
terbutaline; systemic
2.5
8.7
52
211
DHB20
NOMESCO Finland
Polypectomy of internal nose
4.6
8.6
20
44
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.7
8.5
171
1079
4630A
ICD-9 Finland
Acute tonsillitis[TONSILLITIS ACUTA]
7.4
8.5
19
26
R51.80
ICD-10 Finland
Headache
1.7
8.4
180
1152
WZC30
NOMESCO Finland
Teaching
1.8
8.4
146
884
J35.2
ICD-10 Finland
Hypertrophy of adenoids
2.8
8.2
40
146
J01AA02
ATC
doxycycline; systemic
1.5
8.1
669
5693
A02BC02
ATC
pantoprazole; systemic
1.5
8.1
601
5013
4808X
ICD-9 Finland
Viral pneumonia, Pneumonia due to other virus not elsewhere classified
22.2
8.0
11
5
N02AX02
ATC
tramadol; systemic, rectal
1.5
8.0
358
2712
J01FA09
ATC
clarithromycin; systemic
1.5
7.8
271
1947
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
7.7
79
403
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
4.6
7.7
18
40
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
7.4
182
1204
Z50.1
ICD-10 Finland
Other physical therapy
2.4
7.4
49
208
0601, ,
NOMESCO Finland
80.6
7.4
8
*
DE2DG
NOMESCO Finland
Acoustic channel very extensive MRI examination with high intensity magnet
80.6
7.4
8
*
DDD05
NOMESCO Finland
Plastic repair of ossicular chain
+∞
7.3
7
*
38299
ICD-8 Finland
Unspecified otitis media with mastoiditis
+∞
7.3
7
*
DCA40
NOMESCO Finland
Fat patching or other similar technique without opening of tympanic membrane
+∞
7.3
7
*
3811A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic serous otitis media
+∞
7.3
7
*
R42
ICD-10 Finland
Dizziness and giddiness
1.6
7.3
200
1361
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
7.2
53
236
H72
ICD-10 Finland
Perforation of tympanic membrane
30.2
7.2
9
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
7.1
225
1579
ZXA00
NOMESCO Finland
Right side
1.6
7.1
207
1426
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
7.0
198
1355
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
3.9
7.0
20
52
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
6.9
257
1864
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
13.9
6.9
11
8
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.3
6.9
49
216
4222
FHL
Endonasal etmoidectomy
8.3
6.8
14
17
J45.8
ICD-10 Finland
Mixed asthma
2.9
6.8
31
109
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.8
140
886
H69.0
ICD-10 Finland
Patulous Eustachian tube
11.0
6.8
12
11
4661A
ICD-9 Finland
Acute bronchitis and bronchiolitis, Acute bronchiolitis
9.4
6.8
13
14
49300
ICD-8 Finland
Asthma, bronchiale
3.7
6.8
21
58
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
3.3
6.7
25
78
WX402
NOMESCO Finland
General anaesthesia
1.5
6.7
202
1401
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
6.7
92
519
N02BE01
ATC
paracetamol; systemic, rectal
1.5
6.7
874
7961
4931A
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA SINE EXACERBATIONE]
6.5
6.6
16
25
H90
ICD-10 Finland
Conductive and sensorineural hearing loss
12.3
6.6
11
9
H70
ICPC
Otitis externa
3.0
6.5
27
90
SPAT1263
SPAT
Sampling
1.4
6.5
420
3374
C01DA14
ATC
isosorbide mononitrate; oral
1.7
6.4
117
716
S01AA01
ATC
chloramphenicol; ophthalmic
2.1
6.4
58
282
0602, ,
NOMESCO Finland
70.2
6.4
7
*
DBD10
NOMESCO Finland
Reconstruction of external auditory canal
70.2
6.4
7
*
J02AC01
ATC
fluconazole; systemic
1.4
6.4
324
2490
Z71.8
ICD-10 Finland
Other specified counselling
1.4
6.4
365
2867
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
6.4
279
2087
SPAT1301
SPAT
No procedures
1.4
6.4
306
2329
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.4
228
1640
H60.0
ICD-10 Finland
Abscess of external ear
6.6
6.3
15
23
R03BA01
ATC
beclometasone; inhalant
1.7
6.3
116
712
4931B
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA CUM EXACERBATIONE]
11.1
6.3
11
10
A02BC01
ATC
omeprazole; systemic
1.5
6.3
241
1758
H02AB04
ATC
methylprednisolone; systemic
1.7
6.3
112
683
R05
ICPC
Cough
1.5
6.2
249
1829
UDC10
NOMESCO Finland
Tympanoscopy
26.8
6.2
8
*
4129
FHL
Other measure in this category
26.8
6.2
8
*
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
7.1
6.2
14
20
UDM02
NOMESCO Finland
Sinoscopy
3.1
6.2
25
82
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.1
364
2873
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
6.1
83
466
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
4.1
6.1
16
39
J01DC04
ATC
cefaclor; oral
4.1
6.1
16
39
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
6.7
6.0
14
21
J33.8
ICD-10 Finland
Other polyp of sinus
3.2
6.0
23
73
XFE00
NOMESCO Finland
Epicardial ultrasonography
3.3
6.0
22
68
R03CC02
ATC
salbutamol; systemic
1.7
6.0
105
636
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
416
2984
1.64
13.24
3.6
3.2
30.26
31.07
u/l
0.22
396
2826
365
2625
1.59
11.02
3.6
2.6
52.01
60.04
u/l
2.14
346
2459
744
6312
1.59
10.56
9.0
7.6
78.43
78.50
u/l
0.01
714
5970
545
4331
1.53
10.31
6.0
6.1
10.96
12.04
umol/l
1.04
528
4113
307
2212
1.54
8.83
4.4
3.8
1.02
1.02
kg/l
0.08
216
1481
472
3721
1.48
8.79
4.8
3.6
0.04
0.02
estimate
0.41
118
909
62
278
2.30
8.31
3.8
2.5
24.16
24.57
mmol/l
0.33
62
271
388
2967
1.48
8.30
4.5
3.6
70.92
68.68
ng/l
0.02
274
1938
321
2363
1.51
8.27
4.4
4.3
11.20
9.28
mg/mmol
0.29
208
1532
237
1633
1.58
8.24
1.8
1.7
159615814.38
24253886.97
pmol/l
1.20
208
1373
598
4996
1.45
7.91
4.9
3.7
0.00
0.30
estimate
0.51
127
1028
594
4958
1.44
7.88
4.9
3.7
0.00
4.66
estimate
1.07
136
1074
132
797
1.75
7.64
5.5
3.3
4.47
4.56
kpa
0.25
127
774
613
5166
1.44
7.60
9.7
9.1
4.35
4.09
e9/l
1.97
548
4488
586
4912
1.43
7.39
4.9
3.7
0.00
0.00
estimate
-0.00
133
1071
144
915
1.66
6.90
5.9
3.9
5.79
5.81
kpa
0.09
139
888
361
2805
1.43
6.80
4.5
3.1
0.03
0.04
estimate
0.12
112
870
520
4318
1.40
6.64
2.9
2.8
—
—
estimate
—
0
0
259
1898
1.48
6.61
2.9
2.6
5.32
6.34
e6/l
0.81
232
1727
138
878
1.66
6.57
6.0
3.9
1.77
1.82
mmol/l
0.06
119
738
218
1548
1.51
6.48
1.4
1.3
21.96
29.84
iu/ml
0.72
57
432
361
2833
1.41
6.34
3.6
3.5
7.63
8.09
mmol/l
0.94
320
2424
439
3567
1.39
6.27
13.3
12.9
1.19
1.23
inr
0.83
374
3005
44
193
2.33
6.26
1.5
1.8
—
—
—
0
0
262
1944
1.46
6.23
1.7
1.8
0.88
1.22
mg/l
2.53
198
1444
347
2726
1.40
5.99
4.6
3.7
0.00
0.01
estimate
0.96
120
1002
492
4102
1.37
5.88
8.9
6.7
1.21
1.21
mmol/l
0.07
446
3539
845
7745
1.43
5.31
22.8
17.0
13.54
13.40
%
2.24
833
7657
195
1409
1.47
5.25
1.4
1.3
11.61
9.65
u/ml
0.15
90
543
198
1442
1.46
5.11
3.4
2.3
12.70
13.65
umol/l
1.02
188
1346
281
2180
1.39
5.10
3.7
3.3
1710.96
1294.12
ng/l
0.83
238
1840
588
5108
1.33
5.07
5.8
4.9
6.65
6.49
mmol/l
0.94
547
4713
349
2820
1.35
4.87
4.0
3.2
36.59
77.31
e6/l
0.81
273
2123
431
3594
1.33
4.87
5.7
5.0
36.01
36.33
g/l
0.58
412
3368
101
644
1.63
4.78
1.5
1.3
383.21
212.78
u/ml
0.42
95
592
98
624
1.63
4.67
5.0
3.4
1.22
1.23
mmol/l
0.62
84
525
941
8864
1.51
4.57
19.8
13.8
21.74
22.95
mg/l
0.55
807
7194
767
6981
1.35
4.53
4.6
4.3
14.82
14.68
pmol/l
0.92
722
6400
298
2380
1.35
4.42
1.6
1.7
18.08
19.94
nmol/l
1.63
267
2035
303
2433
1.34
4.33
3.7
3.1
0.25
0.41
e6/l
1.32
228
1757
12
24
5.04
4.32
2.7
3.5
4.77
5.07
kpa
0.46
12
24
12
24
5.04
4.32
2.7
3.5
10.72
10.72
kpa
0.00
12
24
707
6382
1.32
4.28
5.0
4.1
11.74
10.55
mm/h
1.50
676
5963
252
1975
1.36
4.20
2.9
2.7
336.89
342.10
umol/l
0.33
234
1769
913
8589
1.43
4.07
21.3
15.8
3.97
3.95
mmol/l
1.34
898
8367
459
3934
1.29
4.02
2.8
2.5
73.05
74.12
nmol/l
0.37
432
3593
911
8580
1.41
3.91
21.3
15.7
139.54
139.56
mmol/l
0.11
898
8385
84
540
1.60
3.88
5.0
4.7
1.23
1.65
mmol/l
0.43
63
394
178
1336
1.40
3.85
3.5
2.3
2.35
2.36
g/l
0.06
166
1238
82
533
1.58
3.63
4.6
3.2
155.88
201.03
ng/l
0.65
64
489
28
130
2.18
3.59
1.4
1.4
—
—
—
0
0
52
302
1.76
3.53
1.0
1.2
3.23
2.88
u/ml
0.08
28
178
961
9178
1.46
3.44
22.8
17.1
76.25
74.99
umol/l
0.59
954
9079
46
260
1.80
3.43
1.1
1.1
1.60
1.76
u/ml
0.10
30
153
163
1232
1.38
3.38
3.6
2.4
22.37
23.27
%
0.37
154
1155
121
869
1.44
3.36
6.1
7.9
1.23
1.01
mmol/l
0.21
89
711
868
8166
1.33
3.30
5.6
5.2
1.93
1.84
mu/l
1.13
829
7599
131
961
1.41
3.24
2.1
1.9
—
—
—
0
0
848
7958
1.31
3.24
4.9
4.4
5.96
5.77
mmol/l
2.99
805
7330
137
1014
1.40
3.22
2.1
1.8
—
—
—
0
0
72
468
1.58
3.22
1.8
1.5
—
—
—
0
0
122
885
1.43
3.21
6.0
7.8
5.16
5.09
kpa
0.32
116
854
122
886
1.42
3.19
6.1
7.8
11.58
12.64
kpa
2.27
116
858
16
61
2.65
3.14
2.0
2.2
—
—
—
0
0
28
138
2.06
3.12
5.5
2.5
14.67
8.06
pmol/l
1.05
28
138
9
20
4.53
3.11
1.0
1.2
97.56
99.75
%
—
9
20
35
188
1.89
3.08
2.0
2.2
131.59
129.46
g/l
0.23
29
152
297
2484
1.27
2.99
1.8
1.7
—
—
—
0
0
420
3661
1.24
2.94
7.0
6.3
1.21
1.21
mmol/l
0.29
399
3374
44
258
1.73
2.94
1.0
1.1
0.35
1.72
u/ml
1.58
21
127
134
1005
1.38
2.92
2.1
2.8
8.51
7.86
umol/l
0.08
110
863
13
46
2.85
2.92
1.0
1.5
—
—
—
0
0
84
583
1.48
2.81
1.8
1.4
—
—
—
0
0
674
6212
1.23
2.67
3.5
3.2
42.57
40.64
u/l
0.31
650
5887
44
267
1.67
2.63
1.0
1.1
4.79
7.34
u/ml
0.43
20
166
872
8278
1.29
2.61
4.8
4.3
1.41
1.44
mmol/l
1.55
832
7740
875
8318
1.28
2.53
4.9
4.4
4.49
4.56
mmol/l
1.29
837
7818
173
1379
1.30
2.52
2.2
1.9
—
—
—
0
0
24
122
1.99
2.51
1.2
1.2
—
—
—
0
0
285
2419
1.24
2.48
2.6
2.1
235.54
264.36
u/l
0.19
276
2310
954
9183
1.36
2.47
12.8
10.5
26.33
25.99
u/l
0.25
935
8925
141
1096
1.33
2.46
8.7
5.6
1.12
1.08
mmol/l
0.96
134
1013
406
3579
1.22
2.45
2.2
2.0
97.92
95.58
pmol/l
0.47
230
1973
31
174
1.80
2.43
1.2
1.3
—
—
—
0
0
827
7823
1.25
2.41
4.2
3.7
1.29
1.22
mmol/l
1.93
784
7283
654
6046
1.21
2.36
5.5
4.5
203.22
1402.86
e6/l
—
9
87
717
6696
1.21
2.30
3.8
3.5
—
—
—
0
0
881
8410
1.27
2.27
5.3
4.8
2.64
2.69
mmol/l
1.04
840
7877
1005
9778
1.46
2.24
28.0
21.0
255.66
252.13
e9/l
1.08
996
9592
1005
9780
1.45
2.22
27.9
20.9
90.00
90.15
fl
0.46
1000
9703
10
35
2.87
2.21
1.9
2.0
0.08
0.11
nmol/l
—
10
20
41
257
1.62
2.20
3.0
2.8
—
—
—
0
0
13
54
2.42
2.20
1.8
2.6
604.71
536.80
ml
—
7
35
1005
9782
1.45
2.19
28.3
21.4
39.89
40.83
%
1.20
1000
9696
1005
9783
1.45
2.18
27.9
21.0
4.53
4.53
e12/l
0.05
994
9581
118
912
1.33
2.16
1.9
2.1
358.88
380.99
nmol/l
0.50
113
847
85
624
1.39
2.15
1.9
1.7
—
—
—
0
0
261
2227
1.23
2.14
2.0
1.4
2.51
2.26
g/l
1.22
172
1402
163
1319
1.28
2.13
4.5
3.5
0.82
0.82
mmol/l
0.18
156
1246
292
2522
1.22
2.12
1.4
1.4
2.13
1.77
u/ml
0.19
84
682
15
68
2.22
2.11
1.1
1.6
—
—
—
0
0
30
175
1.73
2.11
1.3
1.4
—
—
—
0
0
7
20
3.51
2.05
1.9
1.7
1.18
1.23
mmol/l
—
7
20
42
271
1.57
2.02
1.4
1.3
351.04
229.97
u/ml
1.54
28
151
527
4828
1.18
1.95
3.8
3.2
101.90
96.94
ug/l
0.13
505
4539
37
234
1.60
1.95
1.3
1.5
—
—
—
0
0
169
1391
1.25
1.92
3.7
2.9
2.52
2.36
e6/l
0.11
83
675
809
7696
1.21
1.90
6.8
5.5
39.13
38.12
mmol/mol
2.28
776
7249
35
221
1.60
1.86
1.3
1.3
—
—
—
0
0
8
28
2.87
1.86
1.3
1.1
—
—
—
0
0
30
183
1.66
1.83
3.6
3.4
22.59
28.98
mg/l
0.68
21
127
25
145
1.74
1.82
1.4
1.7
—
—
—
0
0
54
378
1.45
1.81
1.3
1.2
—
—
—
0
0
280
2445
1.20
1.79
2.5
2.3
3.00
2.71
mg/l
1.24
245
2111
32
200
1.62
1.78
1.0
1.1
14.42
6.44
u/ml
0.58
16
99
178
1487
1.24
1.78
3.3
2.8
0.80
0.93
e6/l
0.43
94
772
31
193
1.62
1.76
1.6
1.6
6207.24
17448.94
e6/l
1.05
21
145
34
217
1.58
1.75
1.0
1.1
10.38
5.09
u/ml
0.39
16
121
27
163
1.67
1.72
1.1
1.4
—
—
—
0
0
65
476
1.39
1.71
1.9
1.7
—
—
—
0
0
21
118
1.79
1.70
2.5
2.1
—
—
—
0
0
838
8026
1.20
1.70
18.4
13.0
87.93
88.27
ml/min/173m2
0.14
766
7249
52
368
1.43
1.67
1.5
1.7
1.41
7.58
iu/ml
4.19
13
94
10
40
2.51
1.66
1.6
1.1
—
—
—
0
0
8
31
2.59
1.66
1.1
2.0
—
—
—
0
0
8
31
2.59
1.66
1.1
2.0
—
—
—
0
0
155
1287
1.24
1.65
1.7
1.7
1156.67
1170.51
nmol/l
0.07
125
971
117
941
1.27
1.63
3.1
4.5
245.01
251.37
u/l
0.12
110
899
10
42
2.39
1.62
1.1
1.8
—
—
—
0
0
10
42
2.39
1.62
1.0
1.5
—
—
—
0
0
10
42
2.39
1.62
1.1
1.8
—
—
—
0
0
10
42
2.39
1.62
1.1
1.8
—
—
—
0
0
10
42
2.39
1.62
1.1
1.8
—
—
—
0
0
5
14
3.58
1.61
1.4
1.3
1.17
1.18
mmol/l
—
5
14
41
279
1.49
1.61
1.5
1.3
—
—
—
0
0
8
32
2.51
1.59
1.1
1.9
—
—
—
0
0
26
159
1.65
1.59
2.0
2.2
16.80
16.51
%
0.19
26
152
6
20
3.01
1.58
1.0
1.2
—
—
—
0
0
0
43
0.00
1.52
0.0
1.3
—
83.97
—
0
36
7
27
2.60
1.51
1.1
2.5
0.59
0.61
mmol/l
—
7
27
81
630
1.31
1.48
1.0
1.1
—
—
—
0
0
5
16
3.13
1.44
1.0
1.2
—
—
—
0
0
307
2751
1.16
1.42
3.1
3.1
2.35
2.35
mmol/l
0.44
292
2514
9
40
2.26
1.40
1.0
1.5
—
—
—
0
0
12
60
2.01
1.38
1.2
1.5
—
—
—
0
0
0
41
0.00
1.31
0.0
1.3
—
21.45
—
0
33
6
24
2.51
1.30
1.7
1.3
—
—
—
0
0
11
55
2.01
1.27
3.9
3.1
0.64
0.95
index
0.98
11
55
17
99
1.73
1.27
1.5
2.2
32.00
33.19
pg
0.34
17
99
9
44
2.05
1.27
1.2
1.3
—
—
—
0
0
100
820
1.24
1.23
3.6
3.1
—
—
—
0
0
8
37
2.17
1.21
1.4
3.2
0.88
1.24
%
—
8
37
16
93
1.73
1.21
1.2
1.1
—
—
—
0
0
167
1446
1.18
1.18
3.1
2.8
156.02
120.39
ug/g
0.51
140
1153
48
359
1.35
1.18
1.5
1.6
7.97
11.16
u/ml
0.36
15
76
76
607
1.27
1.17
5.9
3.9
102.69
80.49
ng/l
0.78
66
544
35
254
1.39
1.05
1.3
1.5
—
—
—
0
0
25
170
1.48
1.05
1.5
1.6
408.15
335.77
mu/l
0.53
20
138
67
827
0.80
1.03
4.7
6.4
—
—
—
0
0
9
47
1.92
1.02
1.1
1.2
75.75
72.48
%
—
9
42
64
511
1.27
1.02
1.5
1.3
139.71
262.29
miu/ml
3.35
25
248
29
205
1.43
1.01
1.2
1.7
—
—
—
0
0
89
739
1.22
1.01
13.1
6.6
11.30
8.82
mmol/l
1.96
84
710
88
730
1.22
1.00
7.2
7.2
1.24
1.32
mmol/l
0.42
83
715
36
265
1.37
1.00
1.4
1.2
—
—
—
0
0
29
206
1.42
0.99
1.3
1.4
—
—
—
0
0
33
241
1.38
0.97
1.8
1.5
290.30
289.72
ug/g
0.00
20
134
18
116
1.56
0.96
1.1
1.5
—
—
—
0
0
32
233
1.38
0.96
2.4
1.5
—
—
—
0
0
6
27
2.23
0.93
1.5
1.3
9.84
8.26
ug/l
—
6
27
27
192
1.42
0.93
1.0
1.0
0.62
0.28
u/ml
—
9
73
12
70
1.72
0.92
1.1
1.6
—
—
—
0
0
12
70
1.72
0.92
1.1
1.6
—
—
—
0
0
12
70
1.72
0.92
1.1
1.6
—
—
—
0
0
97
821
1.20
0.92
2.6
2.3
33.48
33.09
u/l
0.04
83
680
26
184
1.42
0.92
5.3
2.2
1.16
0.83
nmol/l
0.80
20
156
13
78
1.67
0.91
1.7
1.5
1.58
1.14
promille
—
8
64
15
94
1.60
0.90
1.5
1.7
0.42
0.49
e9/l
1.12
15
94
8
42
1.91
0.88
1.0
1.0
—
—
—
0
0
53
425
1.26
0.84
1.7
1.5
5.40
7.57
u/l
2.17
43
331
58
472
1.24
0.82
1.6
1.5
15.35
14.99
iu/l
0.04
50
376
8
47
1.71
0.80
3.1
1.6
0.85
1.16
nmol/l
—
8
34
8
47
1.71
0.80
1.1
1.2
685.13
322.64
mu/l
—
8
42
245
2245
1.12
0.80
2.2
2.3
—
—
—
0
0
22
156
1.42
0.79
1.6
1.4
—
—
—
0
0
14
90
1.56
0.78
1.1
1.2
—
—
—
0
0
13
82
1.59
0.78
1.1
1.1
99.00
108.62
pmol/l
0.28
13
82
14
210
0.66
0.77
1.8
2.4
0.00
0.00
g/l
-0.00
14
195
70
587
1.21
0.76
4.9
2.4
71.13
70.37
ml/min/173m2
0.06
39
230
69
578
1.21
0.76
2.8
3.8
4.60
4.67
pmol/l
0.20
61
519
90
773
1.18
0.75
2.4
2.5
7878.24
7231.95
u/l
0.07
38
338
18
124
1.46
0.75
2.4
1.3
—
—
—
0
0
5
25
2.00
0.72
1.2
1.3
5.08
6.04
nmol/l
—
5
25
7
39
1.80
0.72
2.3
1.4
—
—
—
0
0
9
56
1.61
0.72
2.1
1.4
75.44
75.07
umol/l
—
9
56
12
76
1.58
0.71
1.1
1.1
—
—
—
0
0
29
221
1.32
0.70
3.5
3.0
7.19
2.30
index
0.82
21
126
7
41
1.71
0.70
3.7
3.4
221.86
111.93
nmol/l
—
7
41
170
1539
1.12
0.70
2.3
2.7
2.43
2.44
mmol/l
0.60
159
1377
9
58
1.56
0.69
1.1
1.8
—
—
—
0
0
9
58
1.56
0.69
1.1
1.8
—
—
—
0
0
27
204
1.33
0.69
1.1
1.1
—
—
—
0
0
34
266
1.29
0.68
1.1
1.1
28.90
7.67
eliau/ml
—
5
40
12
77
1.56
0.68
1.1
1.1
—
—
—
0
0
12
77
1.56
0.68
1.1
1.1
—
—
—
0
0
69
587
1.19
0.66
1.9
2.4
9.08
6.68
ug/l
0.37
60
519
166
1508
1.12
0.65
4.5
3.7
328.49
425.48
ng/l
0.26
111
1063
14
95
1.48
0.64
1.1
1.3
0.16
0.18
nmol/l
—
9
72
0
20
0.00
0.60
0.0
1.0
—
1.11
—
0
20
74
640
1.17
0.60
1.4
1.5
1.21
1.12
ratio
0.30
56
396
350
3311
1.08
0.59
1.9
1.8
1.39
1.30
mmol/l
1.43
294
2836
101
1134
0.88
0.59
1.5
1.7
3.57
3.51
ratio
0.15
71
843
74
641
1.17
0.59
1.4
1.5
0.93
0.94
ratio
0.09
56
397
74
641
1.17
0.59
1.4
1.5
1.22
1.19
ratio
0.11
57
399
42
346
1.22
0.58
1.5
1.5
43.68
0.23
iu/ml
0.47
11
61
80
699
1.16
0.58
1.4
1.6
59.70
59.28
ug/l
0.03
71
619
11
73
1.51
0.56
3.6
3.5
—
—
—
0
0
93
825
1.14
0.55
2.0
2.3
11.50
12.70
nmol/l
0.62
87
746
15
108
1.39
0.53
2.0
1.4
—
—
—
0
0
54
462
1.18
0.52
1.5
1.4
—
—
—
0
0
113
1247
0.89
0.52
3.3
3.2
0.80
0.75
ug/l
0.22
72
781
12
83
1.45
0.51
1.1
1.1
—
—
—
0
0
45
379
1.19
0.51
1.7
2.0
1.55
1.37
g/l
0.83
40
345
11
75
1.47
0.50
1.1
1.1
—
—
—
0
0
10
67
1.50
0.49
1.1
1.0
1417.40
1370.75
miu/ml
—
10
67
77
866
0.88
0.48
1.4
1.5
3.41
3.43
mmol/l
0.08
50
589
15
110
1.37
0.48
2.0
1.4
—
—
—
0
0
15
110
1.37
0.48
1.1
1.5
—
—
—
0
0
15
110
1.37
0.48
2.1
1.4
—
—
—
0
0
226
2122
1.08
0.47
5.5
5.4
2.03
2.53
ug/l
1.03
206
1898
54
467
1.16
0.47
1.9
1.6
0.26
0.25
mg/l
0.08
28
207
10
68
1.47
0.47
3.4
2.8
47.90
44.25
%
—
10
68
10
68
1.47
0.47
6.8
5.6
9.50
8.63
%
—
10
68
7
48
1.46
0.46
2.4
4.6
—
30.62
—
0
11
15
111
1.36
0.46
2.0
1.4
—
—
—
0
0
22
173
1.28
0.46
2.5
2.5
197.67
68.65
ug/min
0.51
12
107
7
50
1.40
0.45
3.6
3.1
783.29
742.62
u/ml
—
7
50
15
112
1.34
0.44
2.1
1.4
—
—
—
0
0
15
112
1.34
0.44
2.1
1.4
—
—
—
0
0
64
566
1.14
0.42
1.5
1.7
473.45
269.97
mu/l
1.65
58
506
13
96
1.36
0.41
1.0
1.1
97.85
96.40
%
0.07
13
89
49
426
1.16
0.41
1.8
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
2.37
—
0
6
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
13
172
0.75
0.41
1.8
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
0.33
—
0
11
5
34
1.47
0.40
1.6
1.8
15.60
14.58
pmol/l
—
5
26
5
34
1.47
0.40
1.4
2.1
87.92
91.20
ng/l
—
5
34
71
636
1.12
0.39
1.4
1.5
—
—
—
0
0
5
35
1.43
0.39
10.2
7.8
111.90
12.73
ug/l
—
5
26
5
36
1.39
0.38
1.4
2.3
149.60
185.53
u/l
—
5
36
9
67
1.35
0.38
1.4
1.3
—
—
—
0
0
22
179
1.23
0.37
1.1
1.2
—
—
—
0
0
17
134
1.27
0.37
1.0
1.1
—
—
—
0
0
33
281
1.18
0.36
1.7
2.3
2.43
4.02
iu/l
1.95
15
126
5
78
0.64
0.35
1.0
1.1
—
—
—
0
0
6
43
1.40
0.35
1.0
1.3
—
—
—
0
0
6
43
1.40
0.35
1.0
1.1
117.00
200.48
iu/ml
—
6
43
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
27
227
1.19
0.34
4.0
3.9
0.28
0.37
iu/ml
0.60
13
135
6
44
1.36
0.34
1.0
1.3
—
—
—
0
0
18
145
1.24
0.33
1.2
1.2
—
—
—
0
0
18
145
1.24
0.33
1.2
1.1
2.61
2.04
eliau/ml
—
8
71
20
164
1.22
0.32
1.9
1.3
—
—
—
0
0
20
164
1.22
0.32
1.9
1.3
—
—
—
0
0
53
590
0.89
0.32
1.5
1.3
—
—
—
0
0
7
53
1.32
0.31
1.1
1.2
7.29
10.96
u/l
—
7
47
89
822
1.09
0.30
1.5
1.5
—
—
—
0
0
7
56
1.25
0.29
1.0
1.2
—
—
—
0
0
7
56
1.25
0.29
1.0
1.1
—
—
—
0
0
25
213
1.18
0.29
2.0
3.8
2.64
2.52
ratio
0.03
18
118
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
7
57
1.23
0.29
1.6
1.2
—
—
—
0
0
36
317
1.14
0.28
2.0
1.8
—
—
—
0
0
24
279
0.86
0.27
1.6
2.2
3.02
3.01
g/l
0.01
24
253
11
86
1.28
0.26
2.7
1.8
—
—
—
0
0
33
291
1.14
0.26
2.2
1.7
—
—
—
0
0
65
702
0.92
0.24
3.0
4.2
21.12
29.72
ug/l
0.16
49
574
12
97
1.24
0.22
1.1
1.0
—
—
—
0
0
17
199
0.85
0.22
2.5
3.0
41.24
33.56
umol/l
0.61
17
185
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
3.3
—
3.66
—
0
10
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
12
98
1.23
0.21
2.6
1.7
—
—
—
0
0
89
943
0.94
0.21
4.2
4.4
31.91
32.11
%
0.06
74
640
32
287
1.12
0.20
1.8
2.9
158.28
185.50
%
1.12
32
280
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
3.88
—
0
8
6
49
1.22
0.20
1.2
1.1
—
—
—
0
0
13
108
1.21
0.20
1.0
1.1
—
—
—
0
0
6
50
1.20
0.19
2.3
2.8
69.00
51.24
umol/l
—
6
43
14
119
1.18
0.17
1.6
3.2
28.58
22.16
nmol/l
0.89
14
111
63
591
1.07
0.17
2.4
2.4
14.27
16.70
au/ml
—
9
62
132
1267
1.05
0.17
2.0
1.7
1.45
1.43
%
0.13
123
1130
132
1267
1.05
0.17
1.6
1.7
952.63
971.99
mu/l
0.09
119
1124
27
243
1.11
0.17
2.0
1.6
—
—
—
0
0
9
78
1.15
0.15
2.2
1.2
—
—
—
0
0
9
79
1.14
0.15
2.2
1.3
—
—
—
0
0
218
2234
0.97
0.14
2.5
2.4
—
—
—
0
0
65
616
1.06
0.14
1.6
1.7
—
—
—
0
0
32
295
1.09
0.14
2.5
2.3
12.53
4.75
umol/l
0.54
27
223
15
132
1.14
0.13
1.1
1.1
1.57
1.49
g/l
0.37
15
118
173
1691
1.03
0.10
1.6
1.6
—
—
—
0
0
5
45
1.11
0.09
3.8
2.6
127.20
161.50
nmol/l
—
5
38
5
48
1.04
0.09
1.8
1.9
2.48
5.67
nmol/l
—
5
37
13
116
1.12
0.09
1.0
1.1
—
—
—
0
0
50
522
0.96
0.09
1.7
1.6
59.13
58.93
ug/l
0.01
50
522
34
321
1.06
0.09
1.5
1.4
—
—
—
0
0
26
277
0.94
0.08
1.3
1.1
—
—
—
0
0
14
154
0.91
0.08
1.4
1.7
—
2253.33
—
0
6
6
71
0.84
0.07
1.7
3.6
2846.67
1323.80
mg
—
6
71
8
76
1.05
0.07
1.4
1.3
—
88.20
—
0
5
8
77
1.04
0.07
1.3
1.6
—
—
—
0
0
145
1422
1.02
0.07
2.4
2.2
—
—
—
0
0
8
93
0.86
0.06
1.0
1.1
—
—
—
0
0
26
274
0.95
0.06
1.3
1.1
—
—
—
0
0
76
777
0.98
0.05
2.4
2.6
0.21
0.21
g/l
0.01
71
723
170
1677
1.02
0.05
4.7
4.5
22.29
21.26
%
0.39
87
782
204
2060
0.99
0.04
2.3
2.3
—
—
—
0
0
27
281
0.96
0.04
3.1
3.5
15.45
4626.37
u/ml
0.70
22
238
14
149
0.94
0.03
1.4
1.3
4.44
5.23
u/ml
—
9
70
14
149
0.94
0.03
1.4
1.3
1.50
2.85
u/ml
—
8
53
78
790
0.99
0.02
1.2
1.3
111.07
140.98
u/ml
0.32
33
301
34
331
1.03
0.02
1.9
1.6
—
—
—
0
0
30
293
1.02
0.01
1.6
2.2
7.84
7.36
g/l
0.83
30
267
30
293
1.02
0.01
1.6
2.2
3.70
3.73
g/l
0.04
30
267
30
293
1.02
0.01
1.6
2.2
4.39
4.21
g/l
0.76
30
267
41
403
1.02
0.01
1.3
1.7
2.35
3.71
mg/l
1.25
27
282
10
94
1.06
0.00
1.0
1.3
—
—
—
0
0
20
199
1.00
0.00
1.2
1.3
—
—
—
0
0
32
318
1.01
0.00
1.9
2.7
88.94
93.45
%
0.54
32
313
21
206
1.02
0.00
1.1
1.1
5.22
13.61
au/ml
—
5
63
32
315
1.02
0.00
1.2
1.3
—
—
—
0
0
26
255
1.02
0.00
1.7
2.2
9.66
10.23
g/l
0.29
26
228
12
121
0.99
0.00
1.3
1.3
—
—
—
0
0
11
107
1.03
0.00
3.6
1.6
—
—
—
0
0
11
113
0.97
0.00
1.0
1.7
—
1175.22
—
0
13
119
1191
1.00
0.00
2.2
2.1
—
—
—
0
0
13
126
1.03
0.00
2.8
3.2
1.16
0.88
nmol/l
—
8
103
59
586
1.01
0.00
2.2
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
1.0
1.1
279.14
282.91
mg/l
—
7
65
0
5
0.00
-0.00
0.0
5.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
7854.83
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
-0.00
1.0
1.2
1.99
1.64
nmol/l
—
7
71
0
5
0.00
-0.00
0.0
2.2
—
10.48
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_SUP_OTINAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_SUP_OTINAS | 1.229 [1.1, 1.37] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.263 |
During the follow-up period (1.1.1998 — 31.12.2019), 641 out of 3842 females with H8_SUP_OTINAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_SUP_OTINAS | 1.206 [1.08, 1.35] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 752 out of 4438 males with H8_SUP_OTINAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_SUP_OTINAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.15% | 0.237% |
| 5 | 0.584% | 1.523% |
| 10 | 1.543% | 3.554% |
| 15 | 3.269% | 6.65% |
| 20 | 5.801% | 11.043% |
Relationships between endpoints
↥Index endpoint: H8_SUP_OTINAS – Suppurative otitis media, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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