Benign neoplasm: Hypopharynx

CD2_BENIGN_HYPOPHARYNX

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D10.7&
  • Hospital discharge: ICD-9 2108
  • Hospital discharge: ICD-8 2108
  • Cause of death: ICD-10 D10.7&
  • Cause of death: ICD-9 2108
  • Cause of death: ICD-8 2108

2 out of 7 registries used, show all original rules.

176

4. Check minimum number of events

None

176

5. Include endpoints

None

176

6. Filter based on genotype QC (FinnGen only)

163

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10
Name in latin
Neoplasma benignum hypopharyngis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 787 363 414
Only index persons 644 303 341
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 59.62 57.19 61.60
Only index persons 59.07 56.24 61.58

-FinnGen-

Key figures

All Female Male
Number of individuals 163 66 97
Unadjusted period prevalence (%) 0.04 0.02 0.04
Median age at first event (years) 58.54 49.68 64.57

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
167
Matched controls
1670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D10.7
ICD-10 Finland
Benign neoplasm: Hypopharynx
+∞
191.6
145
*
UJC01
NOMESCO Finland
Scopy of lower throat
95.5
113.9
61
10
JDB10
NOMESCO Finland
Percutaneous gastrostomy
50.4
30.4
36
9
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
30.2
27.1
36
15
130
Kela drug reimbursment
Malignant tumour
5.7
21.2
49
114
WF002
NOMESCO Finland
Radical radiotherapy
6.9
20.5
36
64
UDQ12
NOMESCO Finland
Flexible laryngoscopy
7.1
20.1
34
58
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
50.3
18.7
22
5
2108A
ICD-9 Finland
Benign neoplasm of lip, oral cavity and pharynx, Hypopharynx
+∞
18.0
17
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
5.5
17.4
39
87
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
100.3
16.9
18
*
C13.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of hypopharynx
188.0
16.8
17
*
R07.0
ICD-10 Finland
Pain in throat
6.2
14.5
27
50
WX408
NOMESCO Finland
General anesthesy, balanced
3.5
13.6
70
286
UDQ22
NOMESCO Finland
Microlaryngoscopy
22.2
12.8
18
9
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
40.9
12.4
15
*
DQA10
NOMESCO Finland
Biopsy of larynx
70.0
11.8
13
*
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
70.0
11.8
13
*
GBB00
NOMESCO Finland
Tracheostomy
21.9
11.4
16
8
ZXE00
NOMESCO Finland
One hour or less
3.0
11.1
92
484
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
46.7
11.1
13
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
5.1
10.9
25
56
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
23.4
10.9
15
7
ENA10
NOMESCO Finland
Biopsy of pharynx
64.2
10.8
12
*
8070/3-C13.9
ICD-O-3
Squamous cell carcinoma, NOS, of hypopharynx, NOS
+∞
10.5
10
*
R4190
NOMESCO Finland
Nutritional therapy
9.4
10.4
21
25
R13
ICD-10 Finland
Dysphagia
4.2
10.2
30
82
ZXD10
NOMESCO Finland
Scheduled procedure
2.9
10.2
84
436
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
32.1
9.5
12
*
C12
ICD-10 Finland
Malignant neoplasm of piriform sinus
+∞
9.5
9
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.8
9.2
22
51
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.4
9.1
19
39
ZXC10
NOMESCO Finland
Use of laser
9.5
9.1
18
21
WX402
NOMESCO Finland
General anaesthesia
2.9
9.0
56
247
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
94.6
8.5
9
*
A03FA01
ATC
metoclopramide; systemic, rectal
2.8
8.3
56
257
UJC02
NOMESCO Finland
Rigid oesophagoscopy
18.3
8.2
12
7
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.6
7.9
64
321
GD1AD
NOMESCO Finland
Thorax CT examination
4.2
7.8
22
58
UDQ02
NOMESCO Finland
Direct laryngoscopy
19.5
7.7
11
6
C13.9
ICD-10 Finland
Malignant neoplasm: Hypopharynx, unspecified
83.7
7.5
8
*
N02AA05
ATC
oxycodone; systemic
2.7
7.4
51
235
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
6.9
7.2
17
27
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
14.6
7.0
11
8
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.9
7.0
22
63
A04AA01
ATC
ondansetron; systemic, rectal
3.5
6.9
26
84
R4110
NOMESCO Finland
Physiotherapy
2.5
6.9
63
330
A02BC05
ATC
esomeprazole; systemic
2.3
6.8
84
504
UJC12
NOMESCO Finland
Flexible oesophagoscopy
23.6
6.7
9
*
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
72.5
6.5
7
*
C01
ICD-10 Finland
Malignant neoplasm of base of tongue
72.5
6.5
7
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.3
6.3
17
43
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.7
6.3
38
162
ENB00
NOMESCO Finland
Excision or exploration of lesion of pharynx
+∞
6.3
6
*
C13.1
ICD-10 Finland
Malignant neoplasm: Aryepiglottic fold, hypopharyngeal aspect
+∞
6.3
6
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
6.3
45
210
ZXA05
NOMESCO Finland
Left side
2.4
6.2
54
276
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.3
6.2
78
467

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
41
149
3.32
9.22
1.4
1.4
—
—
—
0
0
58
258
2.91
9.21
3.1
3.2
2.06
1.78
e6/l
0.12
25
134
82
445
2.66
8.78
4.0
3.2
0.43
0.52
e6/l
0.12
61
334
88
500
2.61
8.50
7.5
6.3
—
—
—
0
0
97
582
2.59
8.30
2.9
2.2
—
—
—
0
0
89
513
2.57
8.28
4.3
3.3
53.95
47.70
e6/l
0.06
68
397
95
565
2.58
8.27
4.9
4.0
54.11
159.10
e6/l
0.90
69
413
43
172
3.02
8.17
1.9
1.7
—
—
—
0
0
126
866
2.85
8.05
14.8
10.9
4.28
4.11
e9/l
0.38
113
748
80
443
2.55
8.04
6.0
4.5
—
—
—
0
0
107
680
2.60
8.01
7.3
4.9
33.76
35.45
g/l
2.31
100
646
114
753
2.62
7.77
11.3
7.7
1.20
1.21
mmol/l
0.88
104
665
115
778
2.54
7.20
7.7
6.5
0.60
0.59
e9/l
0.18
96
663
81
471
2.40
7.10
5.8
4.5
7.41
7.39
ph
2.66
56
337
115
782
2.51
7.06
7.7
6.5
0.04
0.04
e9/l
0.31
97
663
108
716
2.44
6.98
7.6
6.4
0.67
0.67
%
0.05
103
672
115
790
2.46
6.77
8.0
6.5
1.74
1.94
e9/l
0.72
102
696
85
522
2.28
6.37
5.0
3.6
2.33
2.35
mmol/l
0.74
79
475
106
720
2.29
6.15
7.4
6.3
60.33
58.29
%
1.03
101
689
115
809
2.35
6.13
8.2
6.6
0.19
0.20
e9/l
0.27
99
704
78
469
2.24
6.08
3.1
2.5
—
—
—
0
0
99
686
2.09
5.07
15.3
12.7
0.00
0.00
e9/l
0.57
78
559
97
678
2.03
4.73
3.3
2.9
—
—
estimate
—
0
0
37
182
2.33
4.49
1.5
1.5
—
—
—
0
0
62
375
2.04
4.48
2.0
2.0
2.50
2.89
mg/l
0.92
53
331
55
321
2.06
4.36
1.6
1.9
1.17
1.53
mg/l
0.61
50
256
31
145
2.40
4.20
2.7
2.8
66.19
73.65
e9/l
0.37
17
108
52
301
2.06
4.19
3.7
4.1
50.04
281.73
ng/l
1.57
43
240
101
737
1.94
4.13
18.2
13.5
1.23
1.25
inr
0.21
82
614
131
1047
2.17
4.13
5.9
4.2
14.78
14.85
pmol/l
0.12
125
944
38
196
2.22
4.11
1.3
1.2
—
—
—
0
0
93
662
1.91
4.08
2.3
2.1
91.00
92.36
pmol/l
0.08
48
358
70
459
1.90
3.91
8.5
6.7
—
—
—
0
0
115
894
1.92
3.69
8.1
5.2
6.95
6.69
mmol/l
0.53
110
855
108
826
1.87
3.61
11.0
7.5
10.15
11.75
umol/l
1.70
103
788
29
141
2.28
3.59
11.9
10.7
—
—
—
0
0
51
309
1.94
3.55
3.9
3.2
483.91
541.42
mosm/kgh2o
1.42
45
271
148
1273
2.43
3.42
7.1
5.2
2.01
1.98
mu/l
0.08
142
1159
23
106
2.36
3.21
1.3
2.7
—
—
—
0
0
28
141
2.18
3.18
1.3
1.6
—
—
—
0
0
55
355
1.82
3.10
3.8
2.6
3.50
4.92
e6/l
0.62
50
324
62
417
1.77
3.04
3.4
3.0
343.59
354.18
umol/l
0.31
56
358
7
14
5.17
2.76
1.0
1.0
—
—
—
0
0
27
143
2.06
2.70
3.7
2.1
335.96
381.70
nmol/l
0.78
27
132
33
190
1.92
2.62
1.6
1.2
—
—
—
0
0
61
431
1.65
2.42
3.9
3.0
—
—
—
0
0
37
230
1.78
2.31
10.1
7.8
104.03
104.16
mmol/l
0.05
37
230
36
224
1.77
2.24
1.3
1.3
65.45
13.38
u/ml
0.88
11
91
6
14
4.40
2.17
1.2
1.1
—
—
—
0
0
154
1403
2.25
2.16
31.4
17.3
29.65
24.64
mg/l
1.19
139
1168
62
452
1.59
2.12
1.8
1.7
19.15
20.85
nmol/l
0.56
57
375
30
181
1.80
2.06
12.2
9.1
1.34
0.59
mmol/l
0.50
24
155
6
15
4.11
2.06
1.8
1.8
—
—
—
0
0
8
26
3.18
2.04
1.3
1.2
—
—
—
0
0
9
33
2.82
1.96
1.6
1.2
—
—
—
0
0
19
100
2.02
1.95
12.8
9.3
24.89
24.41
mmol/l
0.23
19
100
22
123
1.91
1.91
6.8
5.2
0.00
0.18
%
—
8
34
82
649
1.52
1.90
3.6
2.8
159.42
137.14
ug/l
0.45
77
603
14
66
2.22
1.88
4.4
3.9
—
—
—
0
0
65
491
1.53
1.86
5.7
2.6
50.22
76.42
u/l
1.34
59
459
30
187
1.74
1.85
12.2
8.9
7.42
7.42
ph
0.12
14
107
7
23
3.13
1.82
1.1
1.1
—
—
—
0
0
37
248
1.63
1.75
1.4
1.3
51.89
36.17
iu/ml
0.23
11
74
34
224
1.65
1.72
2.4
1.9
—
—
—
0
0
15
76
2.07
1.70
1.1
1.3
—
—
—
0
0
10
40
2.59
1.70
4.7
3.3
7.40
7.42
ph
—
10
40
26
160
1.74
1.68
3.5
3.9
7.38
7.38
ph
0.03
16
93
8
32
2.57
1.62
4.9
2.5
—
—
—
0
0
33
220
1.62
1.60
1.8
1.8
—
—
—
0
0
7
26
2.76
1.60
1.3
1.2
—
—
—
0
0
22
131
1.78
1.59
6.8
5.1
1.13
1.02
%
—
8
42
36
249
1.57
1.50
1.7
1.6
1014.46
1223.12
nmol/l
0.65
22
192
5
16
3.19
1.45
2.2
1.4
89.72
90.83
%
—
5
16
22
136
1.71
1.41
2.9
2.6
0.17
0.23
e6/l
0.29
22
130
155
1454
1.92
1.37
34.0
20.2
138.78
139.74
mmol/l
3.96
155
1434
6
24
2.55
1.31
4.5
2.5
2.79
4.85
e9/l
—
6
24
8
34
2.42
1.31
1.0
1.6
—
—
—
0
0
155
1458
1.88
1.29
34.5
20.4
3.98
4.00
mmol/l
0.30
155
1437
10
50
2.06
1.19
1.4
1.3
—
—
—
0
0
94
810
1.37
1.18
5.4
3.8
0.24
0.00
estimate
0.63
21
163
20
127
1.65
1.18
6.9
5.0
0.88
0.50
%
—
8
41
14
81
1.80
1.13
1.1
1.2
403.40
86.50
u/ml
—
5
26
93
804
1.35
1.12
5.5
3.8
0.04
9.07
estimate
0.49
23
179
92
795
1.35
1.11
5.4
3.8
0.00
0.00
estimate
-0.00
22
173
129
1177
1.42
1.10
35.6
21.7
13.95
13.68
%
1.42
129
1169
5
21
2.42
1.10
1.0
1.2
—
—
—
0
0
28
199
1.49
1.04
1.5
1.3
800.00
401.70
titre
—
6
47
20
132
1.59
1.03
7.7
5.9
0.00
0.05
%
—
6
37
75
636
1.33
1.00
4.3
3.5
6.26
6.19
ph
0.23
38
372
72
608
1.32
0.98
4.7
4.1
30.73
46.49
ng/l
0.72
53
452
15
93
1.67
0.97
5.2
4.1
—
—
—
0
0
22
152
1.52
0.94
13.2
7.1
11.93
9.75
mmol/l
0.75
22
147
27
195
1.46
0.94
1.8
1.6
—
—
—
0
0
156
1490
1.71
0.92
37.5
22.7
83.37
81.68
umol/l
0.15
156
1477
17
113
1.56
0.86
1.3
1.5
—
—
—
0
0
63
531
1.30
0.85
7.2
4.0
23.39
12.19
mg/mmol
0.43
47
338
25
182
1.44
0.84
1.2
1.3
—
—
—
0
0
47
568
0.76
0.83
4.3
3.3
—
—
—
0
0
11
66
1.71
0.81
2.7
1.5
0.15
0.36
mg/l
—
6
33
12
74
1.67
0.80
2.7
3.3
3.77
4.53
pmol/l
2.63
12
63
0
25
0.00
0.79
0.0
3.8
—
46.88
—
0
25
22
158
1.45
0.79
1.8
1.6
—
—
—
0
0
0
27
0.00
0.78
0.0
1.9
—
10.48
—
0
27
63
537
1.28
0.77
5.5
3.3
7.17
8.07
mmol/l
0.93
56
448
24
180
1.39
0.70
3.4
3.5
3.93
5.79
e9/l
0.80
19
163
5
28
1.81
0.66
6.2
2.7
8.66
8.77
kpa
—
5
28
5
28
1.81
0.66
6.2
2.7
4.80
4.98
kpa
—
5
28
60
518
1.25
0.65
5.4
3.4
191.22
66.55
mg/l
0.43
44
346
142
1351
1.34
0.64
8.8
6.8
42.62
39.68
mmol/mol
1.96
136
1269
13
88
1.52
0.62
2.6
4.5
25.55
24.01
mmol/l
0.51
13
88
6
35
1.74
0.58
4.7
2.7
54.17
57.75
%
—
6
35
6
36
1.69
0.57
1.0
1.2
1.00
0.91
g/l
—
6
36
151
1455
1.39
0.57
22.9
15.0
—
—
—
0
0
6
38
1.60
0.55
1.0
1.1
—
—
—
0
0
15
109
1.41
0.53
4.1
3.5
—
—
—
0
0
9
64
1.43
0.52
2.9
2.7
—
—
—
0
0
36
303
1.24
0.49
1.6
1.8
487.41
44828012.92
pmol/l
0.50
29
261
7
47
1.51
0.48
1.6
1.2
—
—
—
0
0
156
1517
1.43
0.48
44.7
26.5
38.59
40.74
%
3.44
156
1508
156
1517
1.43
0.48
42.9
25.8
91.75
91.53
fl
0.25
156
1508
156
1517
1.43
0.48
43.6
26.1
131.11
136.42
g/l
3.43
156
1509
156
1517
1.43
0.48
42.8
25.8
30.42
30.52
pg
0.28
156
1508
10
68
1.50
0.48
6.4
4.7
0.81
0.86
%
—
10
63
7
49
1.45
0.46
1.0
1.1
—
—
—
0
0
16
121
1.36
0.46
7.9
3.7
—
—
—
0
0
5
31
1.63
0.43
9.0
3.2
7.66
9.97
pmol/l
—
5
31
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
5
34
1.48
0.40
1.0
1.1
1.52
1.52
g/l
—
5
34
18
142
1.30
0.40
4.4
3.0
4.32
4.39
kpa
0.07
18
137
47
416
1.18
0.39
2.9
3.3
0.98
0.80
ug/l
0.34
35
271
146
1415
1.25
0.38
6.4
6.3
2.58
2.67
mmol/l
0.64
140
1312
9
71
1.28
0.37
2.3
2.4
—
—
—
0
0
9
124
0.71
0.36
1.1
1.4
—
—
—
0
0
6
41
1.48
0.36
1.0
1.2
—
—
—
0
0
6
41
1.48
0.36
1.2
1.3
18.59
6.72
u/l
—
6
36
12
91
1.34
0.35
3.9
2.4
0.78
0.57
%
1.06
12
91
138
1334
1.20
0.34
4.6
4.5
1.28
1.28
mmol/l
0.05
129
1228
15
119
1.29
0.33
1.2
1.4
—
—
—
0
0
7
53
1.33
0.31
1.3
2.2
—
—
—
0
0
12
93
1.31
0.31
3.9
2.5
2.37
1.25
%
0.87
12
93
49
444
1.15
0.30
6.2
3.8
0.00
0.01
estimate
0.50
18
161
12
150
0.78
0.28
1.7
1.6
—
—
—
0
0
42
462
0.88
0.26
5.8
3.5
0.00
0.00
estimate
-0.00
19
139
5
41
1.23
0.22
2.8
2.7
54.22
63.58
%
—
5
41
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
179.57
—
0
10
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
10
80
1.27
0.21
1.2
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
3.42
—
0
13
0
14
0.00
0.20
0.0
1.1
—
162.01
—
0
14
42
387
1.11
0.20
1.4
1.4
—
—
—
0
0
11
91
1.22
0.18
1.9
1.8
—
—
—
0
0
7
61
1.15
0.18
2.4
1.7
—
—
—
0
0
10
120
0.82
0.17
1.2
1.2
—
—
—
0
0
8
70
1.15
0.16
1.1
1.1
—
—
—
0
0
141
1384
1.12
0.16
5.4
5.4
1.36
1.44
mmol/l
1.55
135
1280
9
80
1.13
0.15
1.4
1.3
—
—
—
0
0
141
1388
1.10
0.13
5.5
5.5
4.42
4.57
mmol/l
0.95
135
1294
59
614
0.94
0.11
6.2
3.8
0.00
0.03
estimate
0.68
19
148
35
331
1.07
0.10
5.3
4.0
1.02
1.02
kg/l
0.03
27
222
138
1369
1.05
0.04
6.3
5.3
6.26
6.03
mmol/l
0.81
132
1256
18
174
1.04
0.00
2.0
2.1
95.31
117.45
ug/g
0.37
13
139
35
344
1.02
0.00
9.5
5.3
—
—
—
0
0
34
336
1.01
0.00
1.3
1.3
0.97
1.15
u/ml
—
7
92
31
305
1.02
0.00
2.3
1.4
2.49
2.67
g/l
0.20
18
180
69
694
0.99
0.00
4.7
5.6
2.04
2.78
ug/l
0.67
63
631
0
5
0.00
0.00
0.0
2.0
—
1.18
—
0
5
0
5
0.00
0.00
0.0
1.6
—
61.60
—
0
5
0
5
0.00
0.00
0.0
1.6
—
13.32
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1.19
—
0
5
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.00
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
1.80
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
7.47
—
0
6
7
70
1.00
-0.00
5.3
4.4
1.02
1.02
ratio
—
7
65
0
9
0.00
-0.00
0.0
9.3
—
949.78
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
7
69
1.02
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
80.67
—
0
9
5
56
0.89
-0.00
9.2
12.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
7.3
—
0.58
—
0
9

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_HYPOPHARYNX and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_HYPOPHARYNX 1.911 [1.25, 2.93] 0.003
Birth year 0.988 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 51 out of 188 females with CD2_BENIGN_HYPOPHARYNX died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_HYPOPHARYNX 2.396 [1.56, 3.67] < 0.001
Birth year 0.991 [0.98, 1.0] 0.073

During the follow-up period (1.1.1998 — 31.12.2019), 104 out of 275 males with CD2_BENIGN_HYPOPHARYNX died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_HYPOPHARYNX.

N-year risk Females Males
1 0.142% 0.394%
5 0.951% 2.999%
10 2.338% 8.24%
15 4.195% 14.837%
20 6.865% 24.105%

Relationships between endpoints

Index endpoint: CD2_BENIGN_HYPOPHARYNX – Benign neoplasm: Hypopharynx

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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