juvenile dermatomyositis: Juvenile dermatomyositis (JDM) is the early-onset form of dermatomyositis (DM, see this term), a systemic, autoimmune inflammatory muscle disorder, characterized by proximal muscle weakness, evocative skin lesion, and systemic manifestations.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
593 |
6. Filter based on genotype QC (FinnGen only) |
530 |
Control definitions (FinnGen only)
- Control exclude
- RHEUMA_ENDPOINTS
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Dermatopolymyositis (FG)
based on the number of shared cases.
Similar with more cases:
- Dermatopolymyositis
- Systemic connective tissue disorders
- Autoimmune diseases related-to ILD
- Autoimmune diseases
- Finngen Rheumatological endpoints
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3476 | 2143 | 1288 |
| Only index persons | 2514 | 1586 | 928 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.04 |
| Only index persons | 0.05 | 0.06 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 59.02 | 59.14 | 58.69 |
| Only index persons | 55.63 | 55.68 | 55.54 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 530 | 330 | 200 |
| Unadjusted period prevalence (%) | 0.11 | 0.12 | 0.09 |
| Median age at first event (years) | 56.14 | 54.67 | 58.57 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 546
- Matched controls
- 5460
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P01BA02
ATC
hydroxychloroquine; oral
64.0
320.8
184
43
M33.2
ICD-10 Finland
Polymyositis
+∞
313.8
270
*
L04AX03
ATC
methotrexate; systemic
61.9
307.7
229
63
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
141.7
307.7
289
43
L04AX01
ATC
azathioprine; systemic
41.1
257.6
165
57
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
+∞
221.4
197
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
67.6
203.4
113
21
M33.1
ICD-10 Finland
Other dermatomyositis
+∞
194.8
175
*
G72.9
ICD-10 Finland
Myopathy, unspecified
83.7
159.2
85
12
L04AA06
ATC
mycophenolic acid; systemic
54.2
143.7
83
18
H02AB06
ATC
prednisolone; systemic
9.8
123.7
441
1638
M60.9
ICD-10 Finland
Myositis, unspecified
226.1
123.2
123
7
M05BA04
ATC
alendronic acid; oral
9.9
113.8
155
211
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
7.2
112.6
370
1239
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
24.6
111.6
82
39
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
10.3
109.6
142
181
L04AD01
ATC
ciclosporin; systemic
35.8
81.6
52
16
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
442.8
79.0
77
*
H02AB07
ATC
prednisone; oral
6.2
75.9
160
340
L01BA01
ATC
methotrexate; systemic
409.3
73.6
72
*
NXL00
NOMESCO Finland
Biopsy of muscle
280.2
73.3
73
*
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
213.4
73.1
74
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.5
69.7
135
263
M17.1
ICD-10 Finland
Other primary gonarthrosis
9.0
67.0
90
117
M13.9
ICD-10 Finland
Arthritis, unspecified
14.5
65.0
61
47
L88
ICPC
Rheumatoid/seropositive arthritis
365.1
64.9
64
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
8.5
63.3
89
122
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
232.6
61.5
62
*
M60.8
ICD-10 Finland
Other myositis
211.6
56.1
57
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
114.7
48.7
52
5
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.6
46.4
350
1800
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
250.6
45.7
46
*
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
+∞
44.4
42
*
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
14.2
43.8
41
31
M05BA07
ATC
risedronic acid; oral
9.0
42.7
55
67
L99
ICPC
Musculoskeletal disease other
12.6
41.6
42
36
M35.3
ICD-10 Finland
Polymyalgia rheumatica
12.6
39.8
40
34
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.3
39.1
230
991
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
6.2
37.2
68
122
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
10.0
34.0
40
43
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
33.7
32
*
ZX120
NOMESCO Finland
Intravenous
4.4
33.5
94
245
L04AA01
ATC
[U] ciclosporin
58.2
32.7
38
7
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
32.6
31
*
A07EC01
ATC
sulfasalazine; oral, rectal
9.9
32.2
38
41
L28
ICPC
Limited function/disability (L)
3.3
30.4
146
546
L19
ICPC
Muscle symptom/complaint NOS
7.9
28.4
40
54
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
295.9
28.0
28
*
TGC00
NOMESCO Finland
Bronchial lavation
7.6
27.5
40
56
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.4
26.4
73
187
J99.1*M33.9
ICD-10 Finland
Respiratory disorders in dermatopolymyositis
+∞
26.3
25
*
G72.8
ICD-10 Finland
Other specified myopathies
8.9
26.0
33
39
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
35.0
25.9
33
10
XA402
NOMESCO Finland
ENMG
8.7
25.5
33
40
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
25.2
191
907
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
24.8
109
383
C03CA01
ATC
furosemide; systemic
2.6
24.6
209
1048
N03AX16
ATC
[U] pregabalin
2.8
24.3
153
659
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
58.9
24.3
28
5
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
5.6
24.1
48
93
M79.0
ICD-10 Finland
Rheumatism, unspecified
7.6
23.6
34
47
R4120
NOMESCO Finland
Occupational therapy
4.5
23.1
61
150
R4110
NOMESCO Finland
Physiotherapy
2.6
23.1
190
933
XX9XE
NOMESCO Finland
Other ultrasound examination
68.1
23.0
26
*
R50.9
ICD-10 Finland
Fever, unspecified
3.1
22.9
117
448
L04AA13
ATC
[U] leflunomide
239.6
22.8
23
*
Z3226
NOMESCO Finland
Physiotherapist
2.9
22.1
131
543
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
65.3
22.0
25
*
7104A
ICD-9 Finland
Diffuse diseases of connective tissue, Polymyositis
+∞
22.0
21
*
M33.0
ICD-10 Finland
Juvenile dermatomyositis
+∞
22.0
21
*
71610
ICD-8 Finland
Polymyositis and dermatomyositis, Polymyositis
+∞
22.0
21
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.9
22.0
71
203
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
21.9
157
718
A02BC02
ATC
pantoprazole; systemic
2.6
21.9
405
2850
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
52.2
21.3
25
5
M16.1
ICD-10 Finland
Other primary coxarthrosis
7.7
21.0
30
41
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.4
20.7
55
136
XG410
NOMESCO Finland
Flow-volume spirometry
5.1
20.5
45
95
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
7.1
20.2
31
46
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.5
20.2
40
77
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.2
20.0
91
324
R13
ICD-10 Finland
Dysphagia
3.8
19.9
66
192
C08CA05
ATC
nifedipine; systemic
4.2
19.7
55
141
R06.0
ICD-10 Finland
Dyspnoea
2.4
19.7
180
918
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.1
19.4
89
318
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
23.6
19.2
27
12
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
8.4
18.9
25
31
M33
ICD-10 Finland
Dermatopolymyositis
+∞
18.9
18
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
+∞
18.9
18
*
XPX04
NOMESCO Finland
Angioscopy
196.5
18.6
19
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.5
18.6
145
684
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.4
18.3
48
117
M05BX04
ATC
denosumab; parenteral
3.9
18.2
57
159
H02AB09
ATC
hydrocortisone; systemic
6.6
18.2
30
48
N02AX02
ATC
tramadol; systemic, rectal
2.2
18.1
243
1448
NF1AA
NOMESCO Finland
Hip X-ray examination
4.3
18.0
48
119
E0000UV, ,
ATC
2.2
17.7
255
1559
D07AC01
ATC
betamethasone; topical
2.2
17.7
226
1317
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.1
17.7
81
289
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.5
17.2
130
603
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.7
17.1
58
171
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
16.7
16
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.0
16.6
81
299
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.0
16.6
49
131
L29
ICPC
Musculoskeletal sympt/complt other
3.3
15.8
65
217
B01AB05
ATC
enoxaparin; parenteral
2.3
15.8
165
879
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.2
15.7
68
234
NJ3DG
NOMESCO Finland
Very extensive MRI examination of extremities with high intensity magnet
+∞
15.7
15
*
A02BC01
ATC
omeprazole; systemic
2.2
15.6
169
913
L90
ICPC
Osteoarthrosis of knee
6.0
15.5
28
49
SPAT1229
SPAT
Assessment of need for aid
3.7
15.4
50
143
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
15.2
147
756
A28
ICPC
Limited function/disability NOS
2.4
15.1
118
553
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
15.1
222
1348
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
6.0
15.1
27
47
A07AA02
ATC
nystatin; oral
3.6
15.1
51
150
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.5
15.0
38
90
71600
ICD-8 Finland
Polymyositis and dermatomyositis, Dermatomyositis
+∞
14.6
14
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.1
14.6
66
233
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
5.7
14.4
27
49
Z50.1
ICD-10 Finland
Other physical therapy
3.9
14.4
43
116
JN4BD
NOMESCO Finland
Extensive body CT
2.7
14.3
82
330
S18
ICPC
Laceration/cut
2.0
13.7
261
1723
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
13.6
158
870
UJF32
NOMESCO Finland
Coloscopy
2.1
13.6
157
863
G72.4
ICD-10 Finland
Inflammatory myopathy, not elsewhere classified
+∞
13.6
13
*
7103B
ICD-9 Finland
Diffuse diseases of connective tissue, Dermatomyositis[DERMATOMYOSITIS ADULTORUM]
+∞
13.6
13
*
NG4AA
NOMESCO Finland
Lower leg X-ray examination
4.9
13.5
30
64
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
13.2
148
804
GD1AD
NOMESCO Finland
Thorax CT examination
3.2
13.1
53
175
G71.9
ICD-10 Finland
Primary disorder of muscle, unspecified
51.3
12.9
15
*
D07AB08
ATC
desonide; topical
2.7
12.7
77
318
TNG10
NOMESCO Finland
Puncture of knee
71.6
12.6
14
*
A02BC05
ATC
esomeprazole; systemic
1.9
12.5
230
1486
1XC02, ,
NOMESCO Finland
25.0
12.5
17
7
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
25.0
12.5
17
7
J01FF01
ATC
clindamycin; systemic
2.1
12.5
157
888
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.5
12.3
30
69
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
12.3
65
250
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
12.3
91
414
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
12.3
109
537
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.0
12.2
58
210
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
5.7
12.2
23
42
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.3
12.2
32
78
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.8
12.1
63
240
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
5.4
12.1
24
46
B07.9
ICD-10 Finland
Verruca simplex
4.5
12.1
30
70
J05AB01
ATC
aciclovir; systemic
2.1
12.1
139
759
N03AX12
ATC
[U] gabapentin; oral
2.4
12.0
93
432
E000001, ,
ATC
2.2
11.8
119
616
XQ848
NOMESCO Finland
Dermatological photography
4.6
11.8
28
63
J01DB01
ATC
cefalexin; oral
2.2
11.8
447
3661
M01AH01
ATC
celecoxib; oral
2.4
11.7
90
415
M62.9
ICD-10 Finland
Disorder of muscle, unspecified
30.8
11.7
15
5
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.5
11.7
81
357
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.7
11.6
38
109
WX002
NOMESCO Finland
Sedation and analgesia
2.3
11.6
103
506
H02AB04
ATC
methylprednisolone; systemic
2.4
11.6
88
404
R4190
NOMESCO Finland
Nutritional therapy
3.8
11.4
35
96
M04AA01
ATC
allopurinol; systemic
2.6
11.3
68
279
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
11.3
186
1150
H05AA02
ATC
teriparatide; parenteral
35.8
11.3
14
*
318
Kela drug reimbursment
Teriparatide
35.8
11.3
14
*
M81.4
ICD-10 Finland
Drug-induced osteoporosis
35.8
11.3
14
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
11.3
117
612
M79.1
ICD-10 Finland
Myalgia
2.3
11.1
95
459
UJF30
NOMESCO Finland
Ileoscopy through colon
2.6
11.1
67
276
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
44.3
11.0
13
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.1
10.8
46
156
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
10.8
248
1702
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
22.0
10.7
15
7
M48.0
ICD-10 Finland
Spinal stenosis
2.5
10.7
71
306
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
10.7
218
1441
R1250
NOMESCO Finland
Evaluation of functional capability
5.2
10.6
22
44
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
10.6
161
967
H26.3
ICD-10 Finland
Drug-induced cataract
14.6
10.5
17
12
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
10.5
50
181
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
112.1
10.5
11
*
M60.0
ICD-10 Finland
Infective myositis
+∞
10.4
10
*
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
+∞
10.4
10
*
212
Kela drug reimbursment
Gout
+∞
10.4
10
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
16.4
10.4
16
10
EBA10
NOMESCO Finland
Operative extraction of tooth
2.5
10.4
72
317
I50.9
ICD-10 Finland
Heart failure, unspecified
2.3
10.4
86
410
N06AA09
ATC
amitriptyline; systemic
2.6
10.4
62
254
M05BB03
ATC
alendronic acid and colecalciferol; oral
4.9
10.3
23
49
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
10.3
192
1230
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
23.9
10.3
14
6
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
23.9
10.3
14
6
C07AB07
ATC
bisoprolol; oral
1.8
10.2
276
1978
Z3229
NOMESCO Finland
Other healthcare associate professional
2.8
10.2
54
208
A02BC03
ATC
lansoprazole; oral
1.9
10.1
164
1004
M25.5
ICD-10 Finland
Pain in joint
1.9
10.1
163
997
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.4
10.0
37
115
A41.9
ICD-10 Finland
Sepsis, unspecified
4.3
10.0
26
63
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.0
10.0
28
72
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
4.5
9.9
24
55
M05BA06
ATC
ibandronic acid; systemic
5.0
9.9
21
43
M79.7
ICD-10 Finland
Fibromyalgia
7.6
9.8
22
30
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
56.0
9.7
11
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
9.5
74
342
XG466
NOMESCO Finland
Sleep oxymetry
4.2
9.5
25
61
J01DA01
ATC
[U] cefalexin
1.8
9.5
333
2556
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
30.6
9.4
12
*
N28
ICPC
Limited function/disability (N)
7.1
9.4
22
32
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
9.4
9
*
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
+∞
9.4
9
*
5BA08, ,
NOMESCO Finland
22.1
9.4
13
6
L93.0
ICD-10 Finland
Discoid lupus erythematosus
22.1
9.4
13
6
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
4.8
9.4
21
45
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.6
9.3
31
90
R5110, ,
SPAT
2.7
9.3
52
206
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
9.2
201
1344
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
9.1
62
270
WX320
NOMESCO Finland
Spinalanesthesy
2.0
9.1
105
570
R4110, ,
SPAT
2.2
9.0
80
391
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.7
9.0
48
185
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
24.5
8.9
12
5
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
24.5
8.9
12
5
3015
Kela drug reimbursment
Alirocumab and evolocumab for the treatment of hypercholesterolaemia and dyslipidaemia
12.8
8.9
15
12
J05AB11
ATC
valaciclovir; oral
2.1
8.9
93
486
SPAT1231
SPAT
Assessment of adjustments needed in living environment
7.8
8.7
19
25
J01MA12
ATC
levofloxacin; systemic
2.0
8.7
106
586
D07AC13
ATC
mometasone; topical
1.8
8.7
167
1071
A46
ICD-10 Finland
Erysipelas
2.2
8.6
79
391
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
8.6
92
484
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
9.2
8.6
17
19
294
Kela drug reimbursment
Alirocumab and evolocumab for the treatment of hypercholesterolaemia and dyslipidaemia
16.6
8.6
13
8
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.6
8.6
50
202
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
8.5
193
1296
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.3
8.5
22
53
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
4.3
8.5
22
53
C08CA01
ATC
amlodipine; oral
1.7
8.5
215
1489
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
28.0
8.5
11
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.4
8.5
30
91
G71.08
ICD-10 Finland
Other muscular dystrophy
91.4
8.4
9
*
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
8.1
8.4
18
23
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
8.4
141
866
G73.7*M35.0
ICD-10 Finland
Myopathy in sicca syndrome [Sjögren]
+∞
8.4
8
*
M34.1
ICD-10 Finland
CR(E)ST syndrome
+∞
8.4
8
*
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
8.4
8
*
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.6
8.3
27
77
RF420, ,
NOMESCO Finland
9.7
8.3
16
17
WZA10
NOMESCO Finland
Extensive medical or dental certificate
9.7
8.3
16
17
D07AB02
ATC
hydrocortisone butyrate; topical
1.8
8.3
164
1057
TQW80
NOMESCO Finland
Local dermatologic skincare
4.3
8.3
21
50
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
8.1
157
1005
Z3231
NOMESCO Finland
Registered nurse
1.8
8.1
150
948
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
8.0
75
374
NG1DA
NOMESCO Finland
X-ray of knees
22.4
8.0
11
5
M13.0
ICD-10 Finland
Polyarthritis, unspecified
22.4
8.0
11
5
SPAT1153
SPAT
Removal of sutures
1.8
8.0
156
1000
N02AA05
ATC
oxycodone; systemic
2.0
8.0
98
542
B02.9
ICD-10 Finland
Zoster without complication
2.6
7.9
47
192
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.4
7.9
56
249
N99
ICPC
Neurological disease other
7.1
7.8
18
26
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.2
7.8
30
96
WX892
NOMESCO Finland
Monitored bed care
2.5
7.8
49
206
M01AH02
ATC
rofecoxib; oral
2.2
7.7
68
331
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
45.6
7.7
9
*
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.8
7.7
23
62
S06
ICPC
Rash localized
2.9
7.6
36
130
SPAT1254
SPAT
Administration of medicine
2.1
7.6
78
403
S92.3
ICD-10 Finland
Fracture of metatarsal bone
3.5
7.6
26
77
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.4
7.6
27
82
R52.2
ICD-10 Finland
Other chronic pain
3.4
7.6
27
82
NH3EA
NOMESCO Finland
Feet X-ray examination with load
10.2
7.6
14
14
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.8
7.5
121
731
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.0
7.5
34
120
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
7.5
70
349
B01AC24
ATC
ticagrelor; oral
3.4
7.5
27
83
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.6
7.5
44
179
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
81.2
7.4
8
*
M17.5
ICD-10 Finland
Other secondary gonarthrosis
81.2
7.4
8
*
RF120, ,
NOMESCO Finland
13.6
7.4
12
9
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.8
7.4
37
138
A01AB09
ATC
miconazole; local oral
2.3
7.4
56
256
B01AA03
ATC
warfarin; systemic
1.9
7.4
98
556
-50
ICPC
Medication/prescr/renewal
3.4
7.3
26
79
SBA10
NOMESCO Finland
Measurement of salivary flow rate
11.1
7.3
13
12
NG2AA
NOMESCO Finland
Patella X-ray examination
11.1
7.3
13
12
RF410, ,
NOMESCO Finland
11.1
7.3
13
12
L04AB01
ATC
etanercept; parenteral
+∞
7.3
7
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
7.3
7
*
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
+∞
7.3
7
*
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
+∞
7.3
7
*
M60.1
ICD-10 Finland
Interstitial myositis
+∞
7.3
7
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
7.3
7
*
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
+∞
7.3
7
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
7.5
7.2
16
22
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.8
7.2
37
140
TQW40
NOMESCO Finland
Remowal of suture of skin
2.5
7.2
44
182
M01AX01
ATC
nabumetone; oral
3.4
7.2
26
80
Z2221
NOMESCO Finland
Medical doctor
1.7
7.2
147
953
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
7.2
99
569
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
7.1
77
406
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.7
7.1
37
141
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.8
7.1
35
130
HA1AA
NOMESCO Finland
X-ray mammography
2.3
7.1
57
268
XW000
NOMESCO Finland
Bone marrow biopsy
3.2
7.0
28
92
R06AE07
ATC
cetirizine; oral
1.6
7.0
224
1632
D07AD01
ATC
clobetasol; topical
1.9
7.0
93
528
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
7.0
197
1391
SPAT1255
SPAT
Intravenous administration of medicine
2.7
6.9
37
143
D64.9
ICD-10 Finland
Anaemia, unspecified
2.2
6.9
61
297
J01FA10
ATC
azithromycin; systemic
1.6
6.9
293
2283
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.0
6.9
84
462
R53
ICD-10 Finland
Malaise and fatigue
1.7
6.9
139
896
J02AC01
ATC
fluconazole; systemic
1.6
6.9
204
1457
JN4AD
NOMESCO Finland
Body CT examination
2.1
6.9
67
340
ZXE00
NOMESCO Finland
One hour or less
1.6
6.9
198
1404
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.7
6.8
37
144
VALMI, ,
NOMESCO Finland
1.8
6.8
121
751
M10.0
ICD-10 Finland
Idiopathic gout
6.2
6.8
17
28
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
9.5
6.8
13
14
ZXD05
NOMESCO Finland
Urgent procedure
1.7
6.8
159
1067
ZXA05
NOMESCO Finland
Left side
1.8
6.8
119
736
M01AB55
ATC
diclofenac, combinations; oral
2.7
6.8
35
133
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
40.6
6.8
8
*
M05BA01
ATC
etidronic acid; systemic
16.9
6.8
10
6
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
16.9
6.8
10
6
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.1
6.8
67
342
127
Kela drug reimbursment
Transplant complication
7.3
6.7
15
21
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.1
6.7
27
89
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.8
6.7
20
54
SBA00
NOMESCO Finland
Microbiological examinations
4.1
6.7
18
45
A02BA02
ATC
ranitidine; systemic
1.8
6.7
110
668
W19
ICD-10 Finland
Unspecified fall
2.2
6.6
57
275
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
12.4
6.6
11
9
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
12.4
6.6
11
9
SPAT1216
SPAT
Assessment of functional ability
2.0
6.6
80
440
ZXA00
NOMESCO Finland
Right side
1.7
6.6
129
824
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.8
6.6
32
118
S97
ICPC
Chronic ulcer skin
2.5
6.5
39
160
TKC20
NOMESCO Finland
Catheterisation of bladder
2.5
6.5
42
179
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.5
6.5
41
173
QC6S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in hand
70.6
6.4
7
*
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
70.6
6.4
7
*
K90.0
ICD-10 Finland
Coeliac disease
3.3
6.4
24
76
WZA00
NOMESCO Finland
Concise certificate
2.9
6.4
29
103
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
6.4
100
598
D02AX
ATC
Other emollients and protectives
3.5
6.3
21
61
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
6.1
6.3
16
27
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.7
6.3
34
132
C10AX13
ATC
evolocumab; parenteral
11.2
6.3
11
10
M10.9
ICD-10 Finland
Gout, unspecified
3.1
6.3
25
82
SPAT1262
SPAT
Handing over of treatment supplies
1.8
6.3
93
546
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
6.3
6
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
6.3
200
1447
A06AD11
ATC
lactulose; oral
1.9
6.3
85
485
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
7.2
6.3
14
20
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
27.0
6.2
8
*
QCA99
NOMESCO Finland
Other local destruction of skin of upper limb
27.0
6.2
8
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
6.2
99
594
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.0
6.2
17
43
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.5
6.2
21
62
A08
ICPC
Swelling
2.5
6.2
37
152
M01AC06
ATC
meloxicam; systemic, rectal
1.6
6.1
178
1257
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
6.1
62
319
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
6.1
61
312
SAA04
NOMESCO Finland
Special examination of mouth
2.8
6.1
30
111
RF210, ,
NOMESCO Finland
3.7
6.1
19
53
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
8.7
6.1
12
14
L84
ICD-10 Finland
Corns and callosities
3.3
6.1
22
68
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
3.3
6.1
22
68
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
3.4
6.1
21
63
N02AJ13
ATC
tramadol and paracetamol; systemic
5.3
6.1
17
33
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
10.2
6.1
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
218
74
48.37
307.65
1.8
1.2
61.53
—
u/ml
—
14
0
140
13
144.48
279.61
1.4
1.0
—
—
—
0
0
184
149
18.12
197.70
6.3
2.1
718.93
583.63
ug/l
0.13
177
140
161
127
17.56
174.43
2.3
1.3
6.54
4.70
iu/ml
0.50
48
26
109
34
39.81
173.21
1.3
1.1
103.50
—
u/ml
—
8
0
413
1350
9.45
135.70
13.2
2.1
267.25
297.16
u/l
0.16
408
1293
119
96
15.57
125.59
1.6
1.2
12.03
3.65
u/ml
0.51
29
11
118
96
15.40
123.86
1.6
1.1
1.72
3.05
u/ml
—
16
8
133
132
13.00
123.38
1.5
1.1
4.06
3.66
u/ml
—
8
5
49
12
44.76
81.67
1.3
1.2
—
—
—
0
0
87
87
11.71
79.07
1.5
1.4
254.06
0.18
iu/ml
0.47
13
15
73
8
105.14
67.80
1.3
1.0
—
—
—
0
0
50
25
21.92
65.96
1.4
1.2
—
—
—
0
0
53
31
18.83
65.18
1.4
1.2
—
—
—
0
0
48
23
22.78
64.42
1.4
1.2
—
—
—
0
0
48
23
22.78
64.42
1.4
1.2
—
—
—
0
0
48
23
22.78
64.42
1.4
1.2
—
—
—
0
0
47
23
22.27
62.50
1.4
1.1
—
—
—
0
0
144
396
4.58
48.92
2.1
2.3
345.42
389.05
nmol/l
0.74
137
376
431
2498
4.44
48.49
22.1
9.3
4.20
4.08
e9/l
0.51
414
2145
359
2065
3.16
35.88
11.8
6.3
1.21
1.21
mmol/l
0.02
346
1885
54
82
7.20
34.64
9.8
6.1
519.78
182.94
iu/ml
—
9
16
381
2300
3.17
34.31
13.4
7.0
1.21
1.21
mmol/l
0.12
345
1958
209
926
3.04
32.84
2.0
1.4
2.32
2.45
g/l
0.37
164
537
462
3198
3.89
31.65
14.5
3.2
14.83
11.62
mm/h
4.97
455
2934
34
34
10.60
30.33
1.4
1.0
—
—
—
0
0
373
2319
2.92
30.04
6.2
3.6
17.16
3.31
estimate
0.37
80
490
339
2006
2.82
30.03
3.6
2.4
77.65
78.27
nmol/l
0.16
324
1776
368
2294
2.85
29.08
6.2
3.6
0.00
0.00
estimate
0.50
79
488
32
32
10.56
28.52
2.3
1.7
—
—
—
0
0
371
2337
2.83
28.46
6.3
3.6
0.00
0.03
estimate
1.46
79
471
170
752
2.83
25.85
2.6
1.9
—
—
—
0
0
251
1350
2.59
25.78
4.9
3.0
1156.26
1232.50
ng/l
0.15
229
1153
65
160
4.48
24.66
3.0
2.9
—
—
—
0
0
54
116
5.06
24.14
1.8
1.6
—
—
—
0
0
284
1655
2.49
24.12
5.8
3.6
184.62
110.88
e6/l
0.32
208
1159
325
2018
2.51
23.97
8.1
4.9
34.05
35.86
g/l
5.61
317
1898
55
121
4.94
23.91
1.7
1.6
—
—
—
0
0
153
675
2.76
23.06
1.4
1.2
57.01
19.17
iu/ml
1.55
48
187
166
775
2.64
22.26
6.8
3.3
0.80
0.82
mmol/l
1.55
160
738
53
120
4.78
22.24
3.7
3.0
0.00
0.00
g/l
-0.00
53
114
128
530
2.85
21.63
2.5
1.9
—
—
—
0
0
83
271
3.43
21.05
2.5
2.5
22.92
22.20
au/ml
—
8
21
50
115
4.69
20.57
1.3
1.2
—
—
—
0
0
55
137
4.35
20.48
5.2
5.3
33.19
56.64
mg/l
0.60
49
124
131
564
2.74
20.45
2.5
1.8
—
—
—
0
0
54
136
4.30
19.81
5.3
5.3
45.34
49.28
mg/l
0.14
49
121
249
1461
2.29
19.67
4.6
3.1
79.17
65.22
e6/l
0.10
203
1104
89
316
3.17
19.65
4.7
3.3
169.71
206.36
ng/l
0.48
81
300
188
985
2.39
19.27
3.5
2.4
3.43
6.68
e6/l
2.80
176
898
44
97
4.85
19.03
1.8
1.4
—
—
—
0
0
134
616
2.56
18.13
1.3
1.2
30.69
2.93
u/ml
1.13
39
217
201
1108
2.29
18.10
2.8
2.0
3.03
2.93
mg/l
0.22
181
922
28
17
17.28
18.04
2.0
2.1
—
—
—
0
0
221
1270
2.24
17.97
4.6
3.0
0.32
0.55
e6/l
1.13
177
918
184
987
2.30
17.59
4.2
2.7
358.13
337.60
umol/l
1.72
171
861
127
600
2.46
16.03
8.6
5.3
1.05
1.03
mmol/l
0.34
122
556
37
82
4.77
15.88
1.4
1.3
—
—
—
0
0
35
74
4.99
15.87
1.4
1.4
144.38
159.78
au/ml
—
10
25
36
78
4.87
15.87
1.8
1.8
—
—
—
0
0
28
26
11.29
15.15
1.6
1.1
3885.95
15581.68
e6/l
0.86
20
19
101
440
2.59
15.07
3.1
2.2
0.21
0.21
g/l
0.19
96
416
31
62
5.24
14.96
1.1
1.2
6.20
6.27
u/ml
0.00
15
15
146
754
2.28
14.93
3.9
2.8
0.61
0.97
e6/l
2.11
94
376
243
1530
2.06
14.91
6.6
3.0
49.74
33.99
u/l
2.57
230
1438
342
2442
2.07
14.76
10.0
7.0
10.08
11.36
umol/l
2.74
332
2330
31
63
5.16
14.69
1.5
1.5
—
—
—
0
0
189
1099
2.10
14.24
1.4
1.3
1.01
1.74
u/ml
0.71
41
281
80
321
2.75
14.00
2.0
1.5
—
—
—
0
0
35
84
4.38
13.62
2.1
1.4
—
—
—
0
0
34
81
4.41
13.35
1.2
1.2
299.35
231.74
u/ml
0.51
23
42
297
2070
1.95
13.09
17.3
12.7
1.28
1.23
inr
0.87
255
1718
43
124
3.68
13.06
6.1
5.0
2.70
5.64
ratio
0.44
26
73
81
339
2.63
13.02
2.8
2.5
17.34
6.88
ug/l
2.45
71
301
27
56
5.02
12.50
2.0
1.6
—
—
—
0
0
105
506
2.33
12.44
14.2
8.1
10.99
12.49
kpa
2.22
95
489
105
506
2.33
12.44
14.2
8.1
5.20
5.07
kpa
0.62
95
486
32
78
4.30
12.21
1.5
1.5
—
—
—
0
0
22
39
5.84
12.04
1.0
1.1
—
—
—
0
0
24
47
5.30
11.84
1.2
1.4
—
—
—
0
0
102
496
2.30
11.80
14.5
8.2
1.83
0.75
mmol/l
1.21
82
409
28
63
4.63
11.79
1.1
1.2
4.36
7.82
u/ml
0.42
11
28
27
60
4.68
11.54
2.0
1.5
—
—
—
0
0
243
1634
1.88
11.46
3.8
3.8
2.33
2.36
mmol/l
3.52
232
1489
290
2072
1.85
11.19
4.0
2.9
184.92
126.08
ug/l
1.90
279
1919
66
270
2.64
11.06
1.9
1.7
—
—
—
0
0
377
2960
1.88
10.40
6.9
4.3
14.67
4474.82
e6/l
—
6
45
23
49
4.86
10.33
1.1
1.1
—
—
—
0
0
249
1727
1.81
10.32
6.2
3.6
1.43
0.11
estimate
0.45
70
398
130
730
2.02
10.32
1.8
1.7
1147.99
1192.65
nmol/l
0.22
108
552
199
1290
1.85
10.28
7.0
3.4
0.00
0.00
estimate
0.80
77
448
26
63
4.28
10.00
1.4
1.3
—
—
—
0
0
193
1248
1.85
9.99
4.7
3.3
0.36
0.02
estimate
0.46
70
367
346
2664
1.82
9.95
9.8
4.9
6.71
6.74
mmol/l
0.13
337
2537
217
1460
1.81
9.83
2.9
2.4
54.11
67.04
u/l
1.85
204
1341
200
1326
1.80
9.43
1.9
1.6
19.15
20.79
nmol/l
0.93
178
1105
148
894
1.90
9.40
6.5
4.1
209.84
373.21
ng/l
0.86
129
687
22
50
4.54
9.16
1.6
2.0
—
—
—
0
0
23
55
4.32
9.00
1.7
1.9
—
—
—
0
0
151
952
1.81
8.24
2.2
1.7
1.30
1.26
mg/l
0.06
118
732
100
551
2.00
8.23
2.2
2.3
194.88
111.24
ug/g
1.00
87
441
120
719
1.86
7.66
4.4
2.9
3.35
2.31
e6/l
0.68
70
343
33
115
2.99
7.46
1.2
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
33
115
2.99
7.46
4.6
2.8
0.35
0.39
iu/ml
0.36
20
70
55
253
2.31
7.16
4.5
3.3
1.93
1.82
mmol/l
0.06
49
190
12
10
12.24
7.11
1.9
1.4
8.55
8.57
ug/l
—
12
10
34
125
2.83
7.00
3.1
2.8
2.22
2.26
index
0.01
14
66
237
1751
1.62
6.98
6.0
3.5
92.15
61.31
ng/l
0.61
202
1234
14
17
8.42
6.86
1.0
1.2
—
—
—
0
0
14
18
7.95
6.65
1.9
1.4
—
—
—
0
0
265
2037
1.58
6.47
2.4
2.1
95.82
96.23
pmol/l
0.04
150
1047
28
97
2.99
6.41
2.4
1.3
—
—
—
0
0
12
13
9.41
6.31
3.0
2.8
35.33
41.86
g/l
1.64
12
13
16
39
4.20
6.12
1.1
1.0
—
—
—
0
0
94
558
1.83
6.10
3.4
2.9
6.65
8.40
umol/l
0.71
83
498
163
1129
1.63
6.06
7.3
4.0
90.25
90.14
%
0.02
157
1108
148
1017
1.62
5.63
7.3
3.5
1.02
1.02
kg/l
0.52
126
658
136
916
1.65
5.60
1.6
1.7
53846599.49
25333775.06
pmol/l
0.21
130
750
9
7
13.04
5.60
1.1
1.6
—
—
—
0
0
484
4392
1.90
5.42
37.3
14.0
20.59
25.64
mg/l
3.72
451
3505
13
21
6.31
5.41
1.9
4.0
1062.00
1068.48
u/ml
0.01
13
21
31
127
2.53
5.22
1.4
1.2
—
—
—
0
0
14
28
5.10
4.97
1.1
1.1
0.11
0.28
nmol/l
—
5
6
16
46
3.55
4.93
1.5
1.7
—
—
—
0
0
16
46
3.55
4.93
1.5
1.7
—
—
—
0
0
16
46
3.55
4.93
1.5
1.7
—
—
—
0
0
15
33
4.64
4.90
1.5
4.1
360.73
973.42
mg
1.47
15
33
246
1944
1.48
4.82
3.6
2.6
—
—
estimate
—
0
0
30
126
2.46
4.81
1.3
1.2
—
—
—
0
0
10
14
7.25
4.67
1.0
1.0
98.65
231.69
iu/ml
—
10
14
75
452
1.76
4.61
2.4
2.5
320.77
39.68
u/l
0.49
64
376
7
5
14.15
4.58
3.1
1.4
—
—
—
0
0
15
36
4.25
4.54
2.1
1.7
2.64
3.47
mg/l
0.56
15
36
12
23
5.31
4.48
1.0
1.0
—
—
—
0
0
48
258
1.94
4.23
22.8
10.1
16.05
15.80
%
0.27
42
247
33
154
2.22
4.21
2.7
2.0
—
—
—
0
0
9
13
7.02
4.17
2.1
1.4
38.80
82.58
u/l
—
9
13
19
68
2.86
4.16
1.1
1.1
—
—
—
0
0
43
224
2.00
4.14
1.6
1.4
—
—
—
0
0
136
983
1.51
4.00
2.5
3.1
2.47
2.46
mmol/l
0.47
118
891
59
351
1.76
3.80
6.1
3.0
1.21
1.23
mmol/l
2.10
54
286
40
212
1.96
3.69
1.4
1.3
—
—
—
0
0
11
25
4.47
3.64
1.2
1.2
59.55
33.19
mg/l
0.81
11
20
73
468
1.65
3.59
5.5
3.4
1.81
1.51
mmol/l
0.33
68
401
31
151
2.12
3.59
1.5
1.2
—
—
—
0
0
7
9
7.86
3.56
1.0
1.2
—
—
—
0
0
14
46
3.10
3.55
1.2
1.2
—
—
—
0
0
12
31
3.93
3.51
1.5
1.7
—
—
—
0
0
10
22
4.61
3.44
1.0
1.0
—
—
—
0
0
345
3014
1.39
3.39
4.5
3.2
56.14
50.39
u/l
0.53
335
2824
23
104
2.26
3.20
2.1
1.5
—
—
—
0
0
22
98
2.30
3.17
1.4
1.3
—
—
—
0
0
22
98
2.30
3.17
1.4
1.3
—
—
—
0
0
13
44
3.00
3.15
3.4
2.2
90.52
89.10
%
0.60
13
44
9
20
4.56
3.12
1.1
1.0
—
—
—
0
0
45
264
1.77
3.07
2.9
3.4
4.22
4.53
pmol/l
1.72
39
232
6
8
7.57
3.06
1.0
1.0
—
—
—
0
0
28
140
2.05
3.06
2.5
1.9
—
—
—
0
0
29
147
2.03
3.06
1.3
1.5
289.60
281.85
ug/g
0.06
20
88
27
134
2.07
3.01
1.4
1.3
—
—
—
0
0
9
21
4.34
3.00
1.0
1.0
1433.11
1275.33
miu/ml
—
9
21
10
27
3.75
2.89
1.4
1.1
—
—
—
0
0
6
9
6.72
2.87
1.8
1.7
—
—
—
0
0
390
3525
1.37
2.81
5.4
4.3
15.03
14.81
pmol/l
1.01
371
3211
134
1037
1.39
2.66
2.8
2.3
—
—
—
0
0
12
41
2.97
2.63
1.2
1.3
—
—
—
0
0
56
367
1.59
2.55
2.1
1.4
—
—
—
0
0
7
16
4.42
2.48
1.1
1.0
—
—
—
0
0
6
12
5.04
2.40
1.2
1.2
—
—
—
0
0
192
1599
1.31
2.31
3.4
3.3
6.64
7.44
mmol/l
2.00
169
1365
27
463
0.56
2.28
2.3
2.0
3.70
3.50
ratio
0.25
21
363
8
23
3.51
2.27
1.0
1.1
—
—
—
0
0
7
18
3.92
2.26
1.7
2.3
—
—
—
0
0
7
18
3.92
2.26
1.7
2.3
—
—
—
0
0
7
18
3.92
2.26
1.7
2.3
—
—
—
0
0
11
42
2.65
2.15
1.4
1.2
—
—
—
0
0
10
36
2.81
2.14
1.2
1.0
—
—
—
0
0
8
25
3.23
2.10
1.6
2.0
—
—
—
0
0
8
25
3.23
2.10
1.6
2.0
—
—
—
0
0
8
25
3.23
2.10
1.6
2.0
—
—
—
0
0
8
25
3.23
2.10
1.6
2.0
—
—
—
0
0
11
43
2.59
2.09
1.9
1.2
2.04
1.28
nmol/l
1.92
11
38
39
247
1.62
2.07
1.1
1.0
—
—
—
0
0
5
10
5.03
2.07
1.0
1.2
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
7
20
3.53
2.06
1.6
2.9
156.90
125.55
%
—
7
20
10
38
2.66
2.01
1.0
1.1
304.00
292.48
mg/l
—
10
31
7
21
3.36
1.97
1.9
1.4
—
—
—
0
0
61
433
1.46
1.96
5.5
3.1
—
—
—
0
0
15
71
2.14
1.94
1.4
1.2
—
—
—
0
0
22
122
1.84
1.87
1.4
2.0
3.80
4.26
iu/l
—
7
55
8
28
2.88
1.87
1.3
1.1
—
—
—
0
0
8
28
2.88
1.87
1.3
1.1
—
—
—
0
0
6
17
3.56
1.84
2.5
1.4
—
—
—
0
0
6
17
3.56
1.84
2.5
1.4
—
—
—
0
0
5
12
4.19
1.82
1.2
1.2
—
—
—
0
0
5
12
4.19
1.82
1.2
1.1
—
—
—
0
0
5
12
4.19
1.82
1.0
1.1
—
—
—
0
0
97
757
1.34
1.81
1.5
1.5
—
—
—
0
0
13
60
2.20
1.79
1.5
1.5
—
—
—
0
0
180
1533
1.26
1.74
4.0
4.0
8.15
9.08
mg/mmol
0.14
114
952
13
61
2.16
1.73
1.5
1.5
—
—
—
0
0
13
61
2.16
1.73
1.5
1.5
—
—
—
0
0
5
13
3.87
1.72
1.0
1.1
—
—
—
0
0
5
13
3.87
1.72
1.0
1.2
—
—
—
0
0
5
13
3.87
1.72
1.0
1.2
—
—
—
0
0
48
335
1.47
1.70
2.6
2.8
70.75
67.92
ml/min/173m2
0.11
16
146
6
19
3.18
1.66
1.0
1.2
—
—
—
0
0
14
69
2.06
1.66
1.2
1.1
—
—
—
0
0
7
25
2.82
1.65
2.0
1.4
—
—
—
0
0
441
4168
1.30
1.65
6.6
5.3
1.90
1.96
mu/l
0.45
424
3825
7
26
2.71
1.58
2.0
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
26
2.71
1.58
1.1
1.2
—
—
—
0
0
12
57
2.13
1.56
1.6
1.5
—
—
—
0
0
12
57
2.13
1.56
1.6
1.5
—
—
—
0
0
12
57
2.13
1.56
1.6
1.5
—
—
—
0
0
10
45
2.25
1.47
1.2
1.0
—
—
—
0
0
7
29
2.43
1.39
2.0
1.4
—
—
—
0
0
6
23
2.63
1.37
1.0
1.3
—
—
—
0
0
21
129
1.65
1.32
1.2
1.3
319.81
284.19
miu/ml
—
5
59
9
43
2.11
1.31
3.6
2.3
—
—
—
0
0
6
24
2.52
1.30
2.5
1.4
—
—
—
0
0
6
24
2.52
1.30
2.5
1.4
—
—
—
0
0
5
18
2.79
1.28
1.0
1.1
—
—
—
0
0
22
336
0.64
1.25
1.7
1.8
3.96
3.52
mmol/l
1.10
15
238
6
25
2.42
1.24
2.3
1.9
116.17
112.26
ng/l
—
6
25
475
4578
1.29
1.20
35.8
17.4
139.35
139.72
mmol/l
2.36
465
4468
11
57
1.95
1.17
1.0
1.3
0.17
0.20
nmol/l
—
6
42
17
102
1.69
1.17
1.1
1.3
—
—
—
0
0
7
30
2.35
1.12
1.1
1.3
—
—
—
0
0
8
40
2.01
1.12
1.4
1.1
74.75
105.03
pmol/l
—
8
40
10
51
1.98
1.12
3.9
3.6
—
—
—
0
0
23
152
1.54
1.10
1.6
1.6
—
—
—
0
0
17
104
1.66
1.10
3.7
1.9
121.56
129.68
g/l
—
9
81
475
4588
1.27
1.10
36.3
17.6
3.95
3.96
mmol/l
0.55
465
4466
67
540
1.27
1.04
2.8
4.6
2.76
37.24
ug/l
1.58
52
455
5
22
2.28
1.03
3.0
4.0
1.00
1.41
%
—
5
22
489
4756
1.27
0.94
43.1
19.0
75.61
76.29
umol/l
0.10
484
4684
405
4218
0.85
0.94
5.0
4.2
1.49
1.27
mmol/l
3.97
386
3854
24
167
1.46
0.93
1.3
1.4
—
—
—
0
0
280
2619
1.14
0.82
3.4
2.9
—
—
—
0
0
64
531
1.23
0.80
1.4
1.8
1.48
1.45
%
0.17
48
460
20
139
1.46
0.80
1.8
1.7
—
—
—
0
0
447
4329
1.18
0.77
30.1
14.3
84.76
80.55
ml/min/173m2
3.32
433
3997
484
4724
1.22
0.74
29.9
10.8
31.19
25.64
u/l
5.36
478
4562
7
38
1.85
0.73
1.9
2.4
13.71
12.98
%
—
7
38
429
4422
0.86
0.72
5.6
5.0
1.42
1.49
mmol/l
3.05
409
4080
11
68
1.63
0.72
1.0
1.3
—
0.87
nmol/l
—
0
6
435
4219
1.15
0.66
7.3
6.3
39.75
39.40
mmol/mol
0.41
415
3907
433
4446
0.87
0.61
5.7
5.1
4.75
4.68
mmol/l
0.81
413
4128
6
35
1.72
0.58
2.0
2.0
670.17
546.86
ml
—
6
21
10
65
1.55
0.56
1.2
1.6
—
—
—
0
0
6
37
1.63
0.55
1.3
1.2
—
—
—
0
0
137
1256
1.12
0.53
5.0
5.5
3.72
2.79
ug/l
0.40
123
1132
28
224
1.26
0.52
2.9
3.6
19.82
1936.31
u/ml
1.56
22
193
11
154
0.71
0.47
1.2
1.2
1.56
1.57
g/l
0.05
11
154
442
4508
0.90
0.42
6.2
5.8
2.82
2.73
mmol/l
1.47
424
4170
8
56
1.43
0.42
1.3
1.0
—
—
—
0
0
35
296
1.19
0.41
1.3
1.2
78.47
124.54
u/ml
—
10
113
24
195
1.24
0.41
1.4
1.6
0.14
0.28
mg/l
—
5
86
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
33
382
0.86
0.34
2.8
2.0
—
—
—
0
0
81
749
1.10
0.29
1.6
1.5
—
—
—
0
0
10
76
1.32
0.28
6.1
2.7
8.48
8.95
pmol/l
—
10
76
63
577
1.10
0.28
5.6
4.8
30.66
32.13
%
0.63
47
368
13
161
0.80
0.27
1.7
1.2
0.97
0.91
g/l
0.30
13
161
5
38
1.32
0.23
2.0
1.6
337.60
306.81
mu/l
—
5
31
206
1991
1.06
0.23
2.0
1.9
1.53
1.34
mmol/l
1.85
175
1667
5
42
1.19
0.21
1.2
1.5
—
—
—
0
0
10
123
0.81
0.20
1.4
1.2
—
—
—
0
0
7
61
1.15
0.17
1.1
1.8
—
—
—
0
0
25
227
1.11
0.14
2.4
2.1
—
—
—
0
0
40
423
0.94
0.10
2.6
2.1
—
—
—
0
0
430
4331
0.97
0.10
5.8
5.0
5.76
5.96
mmol/l
3.23
404
3958
489
4865
1.05
0.10
51.8
21.9
260.30
250.14
e9/l
1.83
483
4749
6
57
1.05
0.08
1.3
1.3
28.75
27.88
u/l
—
6
48
489
4868
1.04
0.08
51.7
21.8
4.35
4.49
e12/l
7.12
482
4738
11
123
0.89
0.08
1.9
2.8
1.44
1.67
mmol/l
0.84
11
118
12
108
1.11
0.07
1.9
1.5
0.95
0.89
nmol/l
—
7
89
14
128
1.10
0.06
1.8
1.5
—
—
—
0
0
79
771
1.03
0.06
2.8
3.1
0.93
0.76
ug/l
0.36
53
502
20
188
1.07
0.05
2.5
2.1
—
—
—
0
0
101
1029
0.98
0.05
3.7
4.6
22.41
21.89
%
0.14
50
499
12
110
1.09
0.05
1.7
2.1
13609.18
7799.82
u/l
—
6
38
11
102
1.08
0.03
4.5
4.5
40.55
23.88
u/ml
0.30
11
102
53
520
1.02
0.02
9.5
6.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
1.2
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
0.00
2.2
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
96.25
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
1.24
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint DERMATOPOLY_FG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DERMATOPOLY_FG | 2.299 [1.97, 2.68] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.13 |
During the follow-up period (1.1.1998 — 31.12.2019), 396 out of 1305 females with DERMATOPOLY_FG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DERMATOPOLY_FG | 2.482 [2.06, 3.0] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 296 out of 812 males with DERMATOPOLY_FG died.
Mortality risk
Mortality risk for people of age
years, who have DERMATOPOLY_FG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.186% | 0.452% |
| 5 | 1.199% | 2.697% |
| 10 | 3.158% | 6.784% |
| 15 | 5.816% | 11.73% |
| 20 | 10.511% | 19.65% |
Relationships between endpoints
↥Index endpoint: DERMATOPOLY_FG – Dermatopolymyositis (FG)
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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