Malignant neoplasm of gallbladder, including Hilmo

C3_GALLBLADDER_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C23&
  • Hospital discharge: ICD-9 1560
  • Hospital discharge: ICD-8 1560
  • Cause of death: ICD-10 C23&
  • Cause of death: ICD-9 1560
  • Cause of death: ICD-8 1560
  • Cancer registry: Topography ICD-O-3 C23
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

291

4. Check minimum number of events

None

291

5. Include endpoints

None

291

6. Filter based on genotype QC (FinnGen only)

262

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 262 158 104
Unadjusted period prevalence (%) 0.05 0.06 0.05
Median age at first event (years) 70.36 69.69 71.39

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
270
Matched controls
2700
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C23
ICD-10 Finland
Malignant neoplasm of gallbladder
+∞
307.7
250
*
130
Kela drug reimbursment
Malignant tumour
+∞
155.8
134
*
8140/3-C23.9
ICD-O-3
Adenocarcinoma, NOS, of gallbladder
+∞
135.1
118
*
Z51.5
ICD-10 Finland
Palliative care
25.5
124.8
99
60
A03FA01
ATC
metoclopramide; systemic, rectal
13.3
104.4
145
217
WX302
NOMESCO Finland
Thoracal epidural anesthesy
38.8
98.3
63
21
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
54.2
84.2
49
11
H02AB02
ATC
dexamethasone; systemic
139.1
83.8
86
9
A04AA01
ATC
ondansetron; systemic, rectal
26.9
83.8
61
29
A04AA02
ATC
granisetron; systemic, transdermal
+∞
80.3
73
*
L01BC06
ATC
capecitabine; oral
+∞
75.7
69
*
UJK02
NOMESCO Finland
ERCP
24.1
74.0
56
29
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
847.4
69.2
65
*
JN4AD
NOMESCO Finland
Body CT examination
12.2
64.5
74
81
N02AA05
ATC
oxycodone; systemic
7.9
64.3
132
290
JN4BD
NOMESCO Finland
Extensive body CT
13.4
56.8
59
55
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
10.1
56.5
75
99
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
15.1
56.4
54
44
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
140.6
54.1
56
5
JKA20
NOMESCO Finland
Cholecystectomy
18.3
54.1
46
30
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
12.0
51.1
57
59
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
20.2
49.9
40
23
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
47.3
44
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
477.0
42.4
41
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
15.1
40.8
38
29
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
16.6
39.8
35
24
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
35.2
33
*
8000/3-C23.9
ICD-O-3
Neoplasm, malignant of gallbladder
+∞
35.2
33
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
62.8
33.2
38
7
K83.0
ICD-10 Finland
Cholangitis
62.8
33.2
38
7
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
40.0
33.0
41
12
WZC00
NOMESCO Finland
Treatment plan or consultation
4.5
32.1
119
402
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
124.8
31.4
33
*
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
+∞
28.7
27
*
JN3AD
NOMESCO Finland
Abdominal CT examination
5.3
28.6
70
168
JJB30
NOMESCO Finland
Excision of two segments of liver
+∞
27.6
26
*
K83.1
ICD-10 Finland
Obstruction of bile duct
30.7
26.5
35
13
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
+∞
25.4
24
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
25.4
24
*
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
4.8
25.3
70
185
A04AA55
ATC
palonosetron, combinations; systemic
+∞
24.3
23
*
JN4CD
NOMESCO Finland
Very extensive body CT
23.3
23.2
33
16
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
125.2
21.9
23
*
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
21.1
20
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.6
20.6
57
149
ZXE30
NOMESCO Finland
More than five and less than seven hours
8.3
20.3
28
37
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.8
20.2
51
124
WZC30
NOMESCO Finland
Teaching
4.2
20.1
63
181
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
4.0
20.1
69
212
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
7.5
20.0
30
44
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
6.6
19.7
34
58
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
23.8
18.6
26
12
JAH01
NOMESCO Finland
Laparoscopy
7.3
18.2
28
42
JJB10
NOMESCO Finland
Atypcal resection of liver
+∞
17.9
17
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
17.9
17
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
16.8
16
*
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
+∞
16.8
16
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
180.7
16.7
17
*
WX402
NOMESCO Finland
General anaesthesia
3.4
16.3
73
265
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
26.5
16.3
22
9
WX408
NOMESCO Finland
General anesthesy, balanced
3.2
16.1
87
354
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
15.8
15
*
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
+∞
15.8
15
*
B01AB05
ATC
enoxaparin; parenteral
2.8
15.2
116
568
B01AB04
ATC
dalteparin; parenteral
5.7
14.7
29
56
A06AH03
ATC
naloxegol; oral
84.8
14.7
16
*
XX3DW
NOMESCO Finland
Time consuming IT work
5.5
14.7
30
60
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
14.5
14.5
24
18
D77
ICPC
Malignant digestive neopl other/NOS
+∞
13.7
13
*
B01AB10
ATC
tinzaparin; parenteral
4.0
13.6
43
123
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
147.1
13.6
14
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.5
13.4
52
171
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
13.1
82
357
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
73.4
12.7
14
*
L03AA13
ATC
pegfilgrastim; parenteral
73.4
12.7
14
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
6.0
12.6
23
41
C24.09
ICD-10 Finland
Biliary duct or passage NOS
+∞
12.6
12
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.1
12.3
60
227
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.4
12.1
49
165
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
15.6
12.0
19
13
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
11.5
11
*
A79
ICPC
Malignancy NOS
+∞
11.5
11
*
ZX120
NOMESCO Finland
Intravenous
4.2
11.5
32
83
R50.9
ICD-10 Finland
Fever, unspecified
3.1
11.4
54
200
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
36.8
11.4
14
*
JAH00
NOMESCO Finland
Laparotomy
9.9
11.2
22
24
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
11.1
53
197
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
45.3
11.0
13
*
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
8.6
10.8
23
29
A05AA02
ATC
ursodeoxycholic acid; oral
13.7
10.8
18
14
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
10.8
73
328
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
10.5
10
*
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
+∞
10.5
10
*
K82.9
ICD-10 Finland
Disease of gallbladder, unspecified
+∞
10.5
10
*
A04AD12
ATC
aprepitant; systemic
+∞
10.5
10
*
115
Kela drug reimbursment
Breast cancer
+∞
10.5
10
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
10.5
10
*
K81.0
ICD-10 Finland
Acute cholecystitis
8.7
10.0
21
26
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.9
9.7
22
48
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
9.4
9
*
K82.8
ICD-10 Finland
Other specified diseases of gallbladder
+∞
9.4
9
*
C24.0
ICD-10 Finland
Malignant neoplasm: Extrahepatic bile duct
+∞
9.4
9
*
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
+∞
9.4
9
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
9.4
9
*
L02BG04
ATC
letrozole; oral
+∞
9.4
9
*
JLC30
NOMESCO Finland
Pancreatoduodenectomy
+∞
9.4
9
*
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
7.3
9.0
21
31
UJK12
NOMESCO Finland
Peroral cholangioscopy
51.7
8.7
10
*
A07EC02
ATC
mesalazine; oral, rectal
4.1
8.4
24
63
XJA00
NOMESCO Finland
Intraoperative abdominal ultrasonography
+∞
8.4
8
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
8.4
8
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
8.4
8
*
1560A
ICD-9 Finland
Malignant neoplasm of gallbladder and extrahepatic bile ducts, Gallbladder
+∞
8.4
8
*
8160/3-C22.1
ICD-O-3
Cholangiocarcinoma of intrahepatic bile duct
+∞
8.4
8
*
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
+∞
8.4
8
*
PJD99
NOMESCO Finland
Excision of other lymph nodes
+∞
8.4
8
*
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
+∞
8.4
8
*
8010/3-C23.9
ICD-O-3
Carcinoma, NOS, of gallbladder
+∞
8.4
8
*
8160/3-C24.9
ICD-O-3
Cholangiocarcinoma of billiary tract, NOS
+∞
8.4
8
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
8.4
8
*
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
17.8
8.1
12
7
WF002
NOMESCO Finland
Radical radiotherapy
34.5
8.1
10
*
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
34.5
8.1
10
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
7.3
7.9
18
26
D70.82
ICD-10 Finland
Drug-induced neutropenia
46.3
7.8
9
*
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
8.4
7.7
16
20
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
25.8
7.6
10
*
L03AA02
ATC
filgrastim; parenteral
82.3
7.5
8
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
82.3
7.5
8
*
J01MA12
ATC
levofloxacin; systemic
2.3
7.4
65
325
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
6.6
7.4
18
29
JN3GE
NOMESCO Finland
Intraoperative ultrasound examination of abdomen
+∞
7.3
7
*
C24.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of biliary tract
+∞
7.3
7
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
7.3
7
*
JK4ZT
NOMESCO Finland
Percutaneous transhepatic implantation of bile duct prothesis
+∞
7.3
7
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
XQ902
NOMESCO Finland
Other photography
16.3
7.3
11
7
TPX10
NOMESCO Finland
Implantation of vascular injection port
9.2
7.1
14
16
WW500
NOMESCO Finland
Blood transfusion
7.2
6.6
15
22
N02AX02
ATC
tramadol; systemic, rectal
1.9
6.5
128
858
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
71.5
6.5
7
*
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
11.4
6.4
11
10
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
6.3
6
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
YJ1AD
NOMESCO Finland
CT examination of abdomen for dose design of radiotherapy
+∞
6.3
6
*
116
Kela drug reimbursment
Prostate cancer
+∞
6.3
6
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
6.3
6
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
6.3
6
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
6.3
6
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
6.3
6
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
6.3
6
*
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
12.9
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
157
132
27.03
172.35
6.8
1.4
13.71
2.57
ug/l
1.97
146
107
97
57
26.00
123.95
6.6
1.6
1800.67
14.58
u/ml
2.02
89
44
73
20
49.65
121.10
3.0
1.6
502.48
187.62
u/ml
0.26
73
20
54
55
12.02
48.82
1.6
1.3
—
—
—
0
0
80
145
7.42
45.30
1.6
1.1
—
—
—
0
0
100
230
6.32
44.52
7.0
1.9
27.41
6.26
umol/l
2.92
95
199
86
172
6.87
44.18
3.6
1.9
0.19
0.20
g/l
0.83
86
152
190
1103
3.44
19.70
23.7
3.6
20.26
12.23
umol/l
1.92
190
1036
63
196
3.89
17.91
5.9
5.5
6.37
10.53
mmol/l
5.78
63
184
111
495
3.11
17.77
8.8
3.4
86.05
86.75
%
0.11
111
488
126
607
3.02
17.53
5.8
4.0
—
—
—
0
0
125
626
2.86
15.83
3.0
2.0
—
—
—
0
0
180
1119
2.83
14.56
14.6
16.6
1.19
1.33
inr
3.86
157
931
155
906
2.67
13.97
3.6
2.3
—
—
estimate
—
0
0
20
11
19.50
13.59
1.4
1.0
—
—
—
0
0
116
638
2.43
11.24
3.0
1.6
—
—
—
0
0
45
158
3.22
10.35
1.5
1.2
—
—
—
0
0
168
1132
2.28
9.65
19.9
5.5
4.32
4.28
e9/l
0.07
155
964
89
480
2.27
8.61
1.4
1.2
—
—
—
0
0
64
307
2.42
8.04
2.2
1.8
—
—
—
0
0
39
148
2.91
7.79
1.4
1.3
—
—
—
0
0
171
2099
0.49
6.80
5.6
6.6
2.70
2.58
mmol/l
0.85
154
1914
166
2056
0.50
6.75
5.3
5.6
4.71
4.52
mmol/l
1.31
151
1880
170
2083
0.50
6.51
5.2
5.7
6.17
6.08
mmol/l
0.39
158
1880
51
930
0.44
6.50
2.1
2.0
1.30
1.28
mmol/l
0.09
42
771
165
2039
0.51
6.44
5.0
5.5
1.48
1.50
mmol/l
0.22
149
1854
171
1289
1.89
5.85
7.8
3.1
143.67
46.71
u/l
6.67
165
1193
166
2022
0.54
5.58
6.5
7.4
40.50
40.24
mmol/mol
0.12
151
1878
65
363
2.04
5.48
2.6
2.3
11.96
12.12
umol/l
0.06
65
333
5
0
+∞
5.22
1.0
0.0
—
—
—
0
0
32
137
2.52
5.06
7.4
8.1
24.97
25.29
mmol/l
0.26
32
137
161
1961
0.56
5.04
4.5
4.7
1.30
1.25
mmol/l
0.46
145
1766
53
284
2.08
4.97
6.8
7.0
0.88
1.35
mmol/l
0.52
45
235
8
7
11.73
4.81
3.9
1.9
2.29
5.91
nmol/l
—
8
7
155
1176
1.75
4.77
8.0
6.0
1.19
1.21
mmol/l
3.70
138
1028
53
292
2.01
4.59
6.8
6.9
7.43
7.42
ph
0.37
24
173
17
54
3.29
4.57
1.6
1.3
206.39
296.55
ug/g
0.91
12
33
138
1033
1.69
4.30
6.3
5.5
1.19
1.21
mmol/l
3.42
133
940
166
1969
0.59
4.05
4.9
5.7
2.03
1.94
mu/l
0.35
155
1795
7
7
10.22
4.03
1.0
1.0
—
—
—
0
0
42
706
0.52
3.75
3.4
3.8
—
—
—
0
0
95
664
1.66
3.72
4.5
4.9
—
—
—
0
0
53
317
1.84
3.57
7.5
6.2
104.68
104.02
mmol/l
0.50
53
317
31
154
2.14
3.52
7.9
9.0
1.28
1.41
%
0.40
31
154
199
2229
0.59
3.35
52.3
23.2
122.15
133.58
g/l
19.29
199
2197
199
2229
0.59
3.35
51.9
23.0
30.11
30.35
pg
0.98
199
2198
199
2229
0.59
3.35
53.3
23.4
37.04
39.94
%
15.49
199
2198
199
2227
0.60
3.29
52.1
23.0
91.37
91.53
fl
0.16
199
2196
98
710
1.60
3.25
3.5
3.2
7.41
7.40
ph
0.93
75
502
30
152
2.10
3.25
8.4
9.1
0.72
0.67
%
0.36
30
152
89
634
1.60
3.15
2.5
3.1
0.52
0.46
e6/l
0.13
70
460
20
87
2.40
3.09
1.9
1.5
0.73
1.58
ug/l
0.88
20
75
60
868
0.60
2.99
3.9
3.3
6.26
7.00
mmol/l
0.88
51
730
30
158
2.01
2.94
3.1
3.7
1.27
0.75
%
0.54
22
38
199
2209
0.62
2.81
46.1
20.8
74.27
79.36
umol/l
2.00
199
2174
82
587
1.57
2.80
2.5
3.1
—
0.00
estimate
—
0
6
28
148
2.00
2.73
3.0
3.5
1.14
0.26
%
1.20
21
35
10
29
3.54
2.72
1.5
2.0
3.64
4.59
e9/l
—
10
29
61
862
0.62
2.70
3.8
3.4
58.54
41.56
mg/l
0.24
33
543
63
882
0.63
2.67
4.7
4.1
10.59
6.70
mg/mmol
0.27
33
537
98
738
1.51
2.64
2.5
3.2
45.93
123.47
e6/l
0.40
79
559
35
202
1.84
2.64
8.0
7.3
—
—
—
0
0
121
961
1.47
2.48
5.3
4.8
2.43
2.99
%
1.72
116
885
121
963
1.46
2.44
5.5
4.9
9.47
8.89
%
0.89
116
888
190
2114
0.66
2.43
32.2
14.3
—
—
—
0
0
6
12
5.09
2.41
1.0
1.2
—
—
—
0
0
28
155
1.90
2.41
4.7
3.7
—
—
—
0
0
143
1672
0.69
2.31
3.7
4.5
15.24
15.08
pmol/l
0.29
130
1514
146
1699
0.69
2.28
42.2
20.3
329.97
331.01
g/l
0.80
146
1691
121
973
1.44
2.27
5.4
4.9
23.33
26.77
%
2.48
116
907
11
41
2.75
2.23
1.5
1.9
61.18
60.33
%
0.11
11
41
119
961
1.43
2.15
5.4
4.9
0.58
0.68
%
1.41
114
882
82
624
1.45
2.03
14.1
4.2
—
—
—
0
0
5
11
4.61
1.95
1.2
1.3
—
—
—
0
0
199
2170
0.68
1.93
30.3
10.5
35.45
24.07
u/l
7.16
199
2084
103
824
1.40
1.92
2.9
4.0
95.40
133.38
e6/l
0.43
80
579
26
152
1.79
1.91
3.2
3.7
0.20
0.06
%
0.55
20
32
50
354
1.51
1.76
1.5
1.7
33.96
29.14
s
1.32
50
341
126
1062
1.35
1.65
5.6
4.8
0.62
0.59
e9/l
0.59
110
890
10
204
0.47
1.57
1.6
1.5
—
—
—
0
0
24
147
1.69
1.53
4.7
5.2
—
—
—
0
0
5
15
3.38
1.53
1.0
1.1
—
461203.75
—
0
8
126
1072
1.33
1.51
5.6
4.8
0.04
0.04
e9/l
0.07
109
899
9
38
2.41
1.47
2.7
2.6
—
—
—
0
0
26
390
0.63
1.43
1.0
1.3
37.68
40.65
iu/ml
0.04
13
131
8
162
0.48
1.41
1.9
2.5
—
20.82
—
0
11
126
1082
1.31
1.38
5.7
4.8
1.57
1.80
e9/l
2.77
112
933
5
17
2.98
1.36
1.4
1.6
13.32
26.61
ng/l
—
5
17
127
1102
1.29
1.26
5.7
4.8
0.16
0.20
e9/l
1.70
112
936
98
1146
0.77
1.23
2.2
2.2
95.68
94.73
pmol/l
0.08
58
552
5
19
2.66
1.22
1.6
1.1
—
—
—
0
0
24
352
0.65
1.20
1.1
1.3
36.65
15.39
u/ml
—
10
127
6
26
2.34
1.19
1.3
1.1
—
—
—
0
0
80
660
1.30
1.15
4.3
4.2
0.00
0.00
estimate
-0.00
35
218
8
40
2.03
1.13
2.5
3.5
4.88
5.15
kpa
—
8
40
8
40
2.03
1.13
2.5
3.5
2.05
3.36
mmol/l
—
8
26
8
40
2.03
1.13
2.5
3.5
8.29
8.11
kpa
—
8
40
15
89
1.73
1.10
1.1
1.2
—
—
—
0
0
7
33
2.15
1.06
1.7
1.3
—
—
—
0
0
95
809
1.27
1.06
2.9
3.4
—
—
—
0
0
27
189
1.48
1.04
1.2
1.3
—
—
—
0
0
23
157
1.51
1.00
3.3
3.9
0.13
0.00
%
0.48
15
29
9
49
1.86
0.99
1.2
1.1
—
—
—
0
0
55
440
1.31
0.98
4.4
3.6
—
—
—
0
0
5
23
2.20
0.98
1.2
1.5
90.42
89.58
%
—
5
23
5
23
2.20
0.98
1.8
2.4
29.40
33.22
pg
—
5
23
21
145
1.49
0.88
3.2
3.3
4.77
5.21
kpa
1.45
21
140
6
30
2.02
0.87
1.2
1.0
—
—
—
0
0
13
80
1.66
0.86
1.8
1.3
—
—
—
0
0
8
140
0.56
0.85
1.0
1.4
—
53.62
—
0
11
6
32
1.89
0.82
1.3
1.1
—
—
—
0
0
6
32
1.89
0.82
1.2
1.1
—
—
—
0
0
162
1492
1.21
0.82
5.1
4.8
—
3.43
—
0
6
113
1007
1.21
0.80
4.1
4.2
43.49
120.57
ng/l
0.65
91
772
5
96
0.51
0.79
1.4
1.9
4.04
3.37
mmol/l
—
5
78
5
99
0.50
0.79
1.6
2.0
132.88
824.16
ug/l
—
5
93
16
107
1.53
0.78
2.6
2.2
0.00
0.00
estimate
—
5
35
45
363
1.29
0.77
2.4
3.1
4.67
3.12
e6/l
0.25
20
167
16
108
1.51
0.75
1.3
1.3
—
—
—
0
0
7
38
1.86
0.74
1.7
3.1
—
—
—
0
0
11
70
1.60
0.66
3.4
3.2
7.43
7.41
ph
1.24
11
70
5
29
1.74
0.64
1.4
1.4
—
—
nmol/l
—
0
0
14
197
0.69
0.61
1.7
2.4
0.74
0.31
e6/l
0.52
14
184
12
174
0.68
0.61
1.6
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
19
140
1.38
0.60
3.2
3.4
7.41
7.42
ph
0.12
19
110
0
22
0.00
0.59
0.0
2.4
—
—
—
0
0
10
149
0.66
0.58
3.8
2.4
1.14
1.17
%
—
10
149
8
122
0.65
0.56
1.0
1.2
—
116.50
u/ml
—
0
45
72
635
1.18
0.55
3.6
3.8
0.00
0.00
estimate
-0.00
31
191
10
147
0.67
0.55
3.8
2.4
0.56
0.62
%
—
10
147
68
766
0.85
0.52
1.9
1.7
19.23
20.28
nmol/l
0.27
63
650
102
933
1.15
0.49
25.0
10.0
0.00
0.00
e9/l
0.77
84
756
40
469
0.83
0.48
1.2
1.3
0.68
1.33
u/ml
—
9
125
17
130
1.33
0.45
2.8
2.4
—
—
—
0
0
6
94
0.63
0.43
1.3
1.2
—
—
—
0
0
19
151
1.28
0.40
1.7
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
22
179
1.25
0.38
2.1
1.4
65.65
66.76
g/l
0.22
22
158
5
36
1.40
0.38
1.4
1.1
0.92
0.85
g/l
—
5
36
61
548
1.15
0.38
1.8
1.8
477.34
443.97
pmol/l
0.43
53
448
125
1176
1.12
0.37
3.9
4.2
0.00
0.00
estimate
-0.00
39
237
9
70
1.30
0.37
4.1
4.5
25.36
25.17
mmol/l
—
9
65
12
157
0.75
0.37
1.1
1.3
—
—
—
0
0
54
600
0.88
0.35
5.1
4.3
2.38
1.98
ug/l
0.51
44
527
127
1201
1.11
0.34
4.1
4.2
0.00
0.00
estimate
0.50
38
234
50
557
0.87
0.34
4.4
4.3
1.02
1.02
kg/l
0.37
39
370
126
1192
1.11
0.33
4.0
4.2
0.00
0.00
estimate
-0.00
41
248
31
267
1.18
0.33
1.5
1.5
—
—
—
0
0
25
215
1.18
0.28
2.3
2.2
0.17
0.00
estimate
—
6
48
5
72
0.69
0.26
2.8
4.9
—
—
—
0
0
52
477
1.11
0.24
1.8
1.8
1134.29
1185.94
nmol/l
0.15
42
370
18
153
1.19
0.23
1.1
1.2
—
—
—
0
0
95
901
1.08
0.23
4.2
4.1
0.00
0.03
estimate
0.78
28
189
35
315
1.13
0.23
1.5
1.2
—
—
—
0
0
5
42
1.19
0.21
2.2
2.0
6.09
4.56
mmol/24h
—
5
37
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
1.20
—
0
10
0
10
0.00
0.21
0.0
1.2
—
8.11
—
0
10
0
12
0.00
0.21
0.0
2.9
—
26.67
—
0
6
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
51
1.18
0.19
1.0
1.2
438.17
463.22
mg/l
—
6
46
7
61
1.15
0.17
2.1
1.8
110.71
130.93
g/l
—
7
42
7
62
1.13
0.17
2.1
1.8
—
—
—
0
0
20
223
0.89
0.15
3.5
2.7
4.40
4.33
kpa
0.06
20
216
29
266
1.10
0.14
2.2
1.7
—
—
—
0
0
23
208
1.12
0.14
2.3
1.2
—
—
—
0
0
25
274
0.90
0.14
3.0
3.1
7.42
7.39
ph
1.96
14
177
107
1037
1.05
0.13
2.4
2.5
78.99
80.52
nmol/l
0.21
100
912
31
330
0.93
0.10
2.7
2.8
0.86
0.79
ug/l
0.22
20
214
60
624
0.95
0.10
2.7
3.3
—
0.10
—
0
21
48
502
0.95
0.09
1.4
1.6
1.95
1.28
mg/l
0.62
39
393
6
57
1.05
0.08
1.3
1.1
—
—
—
0
0
30
283
1.07
0.08
1.5
1.3
128.00
502.17
titre
—
5
83
6
71
0.84
0.07
3.3
5.3
3.48
3.91
mmol/l
—
6
71
54
522
1.04
0.07
4.0
4.6
96.98
313.16
ng/l
1.40
42
451
8
94
0.85
0.07
5.1
3.7
—
—
—
0
0
54
551
0.98
0.03
3.6
3.8
—
0.00
—
0
6
94
949
0.99
0.01
3.8
3.7
6.08
6.26
ph
0.81
55
522
38
386
0.98
0.00
1.5
1.3
2.02
2.69
g/l
2.77
26
207
12
119
1.01
0.00
1.9
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
278.32
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
77
0.91
-0.00
1.3
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1628.50
—
0
6
9
94
0.96
-0.00
1.3
1.3
—
—
—
0
0
12
120
1.00
-0.00
1.8
2.5
12.94
16.47
nmol/l
0.74
12
109
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
7.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
1.86
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_GALLBLADDER_WIDE – Malignant neoplasm of gallbladder, including Hilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).