brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
582 |
4. Check minimum number of eventsNone |
582 |
5. Include endpointsNone |
582 |
6. Filter based on genotype QC (FinnGen only) |
523 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D33
- Name in latin
- Neoplasma benignum medullae spinalis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Spinal cord
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2876 | 1502 | 1358 |
| Only index persons | 2586 | 1356 | 1230 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.04 |
| Only index persons | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 52.72 | 54.48 | 50.76 |
| Only index persons | 52.31 | 53.93 | 50.53 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 523 | 285 | 238 |
| Unadjusted period prevalence (%) | 0.10 | 0.10 | 0.11 |
| Median age at first event (years) | 54.97 | 54.18 | 55.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 545
- Matched controls
- 5450
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D33.45
ICD-10 Finland
Benign Schwannom in the nerve root of the spinal cord
+∞
307.7
298
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
+∞
236.1
209
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
17.8
155.1
139
103
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
40.0
117.6
73
21
9560/0-C72.0
ICD-O-3
Schwannoma, NOS, of spinal cord
+∞
92.4
86
*
D33.43
ICD-10 Finland
Spinal cord
+∞
89.0
83
*
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
+∞
89.0
83
*
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
+∞
86.8
81
*
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
17.9
80.9
68
43
D33.4
ICD-10 Finland
Benign neoplasm: Spinal cord
+∞
79.1
74
*
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
396.2
71.4
70
*
D33.47
ICD-10 Finland
Other benign neurofibromas in the nerve root of the spinal cord
+∞
64.9
61
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
15.0
51.6
47
34
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.2
48.2
165
508
D43.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal cord
510.4
48.1
47
*
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
10.0
47.7
57
63
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
16.3
47.3
41
27
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
14.0
46.5
44
34
D33.41
ICD-10 Finland
Myxopapillary epndymoma of the spinal cord (grade I)
+∞
43.3
41
*
N03AX16
ATC
[U] pregabalin
3.4
40.3
206
818
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.3
40.1
125
355
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.6
37.6
78
158
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.5
36.4
103
271
D33.46
ICD-10 Finland
Benign neurofibroma in the nerve root of the spinal cord
+∞
35.8
34
*
N03AX12
ATC
[U] gabapentin; oral
3.4
33.4
156
577
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
44.0
30.3
37
9
D33.42
ICD-10 Finland
Hemangioblastoma of the spinal cord
+∞
28.4
27
*
N02AX02
ATC
tramadol; systemic, rectal
2.7
28.2
304
1739
N02BF01
ATC
gabapentin; oral
3.6
27.7
105
337
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
25.8
24.7
34
14
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
24.7
194
937
9394/1-C72.0
ICD-O-3
Myxopapillary ependymoma of spinal cord
+∞
24.1
23
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
23.5
114
424
XKD06
NOMESCO Finland
Physiologic investigation of micturition
5.8
22.0
42
78
9530/0-C70.1
ICD-O-3
Meningioma, NOS, of spinal meninges
228.8
21.8
22
*
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
+∞
21.0
20
*
9391/3-C72.0
ICD-O-3
Ependymoma, NOS, of spinal cord
+∞
19.9
19
*
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
76.4
19.8
22
*
M03BX01
ATC
baclofen; systemic
6.8
19.4
31
48
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
103.7
18.7
20
*
R4110
NOMESCO Finland
Physiotherapy
2.3
18.4
191
1024
9560/0-C72.9
ICD-O-3
Schwannoma, NOS, of nervous system, NOS
+∞
17.8
17
*
Z31.5
ICD-10 Finland
Genetic counselling
4.0
17.1
51
137
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.5
17.0
64
202
Q85.09
ICD-10 Finland
Unspecified neurofibromatosis
+∞
16.8
16
*
L28
ICPC
Limited function/disability (L)
2.4
14.7
126
614
2253A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal cord
+∞
14.6
14
*
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
+∞
14.6
14
*
22530
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal cord
+∞
14.6
14
*
WX402
NOMESCO Finland
General anaesthesia
2.2
14.6
155
828
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
154.0
14.5
15
*
M54.4
ICD-10 Finland
Lumbago with sciatica
2.3
14.0
130
656
N18
ICPC
Paralysis/weakness
6.4
13.8
23
37
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
4.6
13.7
33
75
AA1AD
NOMESCO Finland
CT of head and brain
2.1
13.7
186
1088
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.9
13.7
68
253
M54.5
ICD-10 Finland
Low back pain
2.0
13.4
230
1461
N02BF02
ATC
pregabalin; oral
3.1
13.4
59
205
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.8
13.3
41
113
SPAT1153
SPAT
Removal of sutures
2.0
12.9
194
1174
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.4
12.9
107
513
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.7
12.6
76
313
C72.01
ICD-10 Finland
Malignant tumor of the spinal cord grade II glioma
+∞
12.5
12
*
C72.00
ICD-10 Finland
Malignant tumor of the spinal cord without histology
+∞
12.5
12
*
D33.30
ICD-10 Finland
Acoustic neuroma
20.6
12.5
18
9
N06AX21
ATC
duloxetine; oral
2.5
12.4
87
385
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
11.4
12.1
22
20
XKD00
NOMESCO Finland
Uroflowmetry
2.3
12.1
101
484
N28
ICPC
Limited function/disability (N)
5.8
12.0
22
39
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.4
12.0
90
411
S18
ICPC
Laceration/cut
1.9
12.0
290
2044
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
10.0
11.8
23
24
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.0
11.8
56
203
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.9
11.7
58
215
ZXH01
NOMESCO Finland
Procedure performed within operation theatre
66.4
11.6
13
*
M48.0
ICD-10 Finland
Spinal stenosis
2.5
11.6
83
371
D33.14
ICD-10 Finland
Hemangioblastoma and cerebellum
+∞
11.5
11
*
Q85.0
ICD-10 Finland
Neurofibromatosis (nonmalignant)
+∞
11.5
11
*
9161/1-C72.0
ICD-O-3
Hemangioblastoma of spinal cord
+∞
11.5
11
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.5
11.4
28
65
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
35.8
11.3
14
*
G82.2
ICD-10 Finland
Paraplegia, unspecified
25.6
11.2
15
6
R33
ICD-10 Finland
Retention of urine
2.8
10.8
55
207
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.3
10.6
88
420
ZXC40
NOMESCO Finland
Use of ultrasound
14.6
10.5
17
12
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
112.1
10.5
11
*
D43.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other parts of central nervous system
+∞
10.4
10
*
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
10.9
10.3
19
18
ACB19
NOMESCO Finland
Excision of lesion of peripheral nerve other or unspecified
19.2
10.3
15
8
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
10.1
256
1800
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.4
9.8
69
306
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.5
9.5
65
284
2312
FHL
Extirpation or destruction
101.7
9.4
10
*
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
101.7
9.4
10
*
Q85.82
ICD-10 Finland
of Hipple-Lindau syndrome
+∞
9.4
9
*
C72.09
ICD-10 Finland
Malignant tumor of the spinal cord other histology
+∞
9.4
9
*
N06AA09
ATC
amitriptyline; systemic
2.5
9.3
64
280
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
9.0
125
723
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
8.7
270
1983
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
8.6
72
344
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
8.5
207
1420
R4120
NOMESCO Finland
Occupational therapy
2.6
8.5
49
197
N75
ICPC
Benign neoplasm nervous system
91.4
8.4
9
*
NA7FT
NOMESCO Finland
Labeling lesion in spinal area with X-ray guidance
91.4
8.4
9
*
M03BX02
ATC
tizanidine; oral
1.7
8.3
343
2707
R1250
NOMESCO Finland
Evaluation of functional capability
4.2
8.3
22
54
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.9
8.2
18
38
XKC03
NOMESCO Finland
Water cystometry
3.7
7.9
25
70
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.8
7.8
39
146
A28
ICPC
Limited function/disability NOS
2.0
7.7
99
556
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
25.4
7.6
10
*
AWE00
NOMESCO Finland
Reoperation for deep heamorrhage in surgery of the nervous system
25.4
7.6
10
*
G82.1
ICD-10 Finland
Spastic paraplegia
81.2
7.4
8
*
L03
ICPC
Low back symptom/complaint
1.7
7.4
169
1131
N02BE01
ATC
paracetamol; systemic, rectal
2.3
7.3
495
4432
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.5
7.3
25
74
2311
FHL
Resection
+∞
7.3
7
*
D16.6
ICD-10 Finland
Benign neoplasm: Vertebral column
+∞
7.3
7
*
9161/1-C71.6
ICD-O-3
Hemangioblastoma of cerebellum, NOS
+∞
7.3
7
*
Z3226
NOMESCO Finland
Physiotherapist
1.9
7.2
103
598
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
7.2
398
3331
ZXD35
NOMESCO Finland
Usual procedure
3.4
7.2
25
75
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
20.3
7.2
10
5
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
7.0
196
1379
M79.6
ICD-10 Finland
Pain in limb
1.6
7.0
248
1851
TAB00
NOMESCO Finland
Lumbar puncture
2.7
7.0
36
137
H02AB02
ATC
dexamethasone; systemic
2.0
6.8
73
383
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
40.6
6.8
8
*
UKC02
NOMESCO Finland
Cystoscopy
1.9
6.7
90
511
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.7
6.5
34
130
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
6.5
78
427
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.8
6.5
31
113
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.0
6.5
18
46
ZXC95
NOMESCO Finland
Use of surgical navigator
7.5
6.4
14
19
D48.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Peripheral nerves and autonomic nervous system
70.6
6.4
7
*
U05
ICPC
Urination problems other
2.6
6.4
37
149
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
11.2
6.3
11
10
1922A
ICD-9 Finland
Malignant neoplasm of other and unspecified parts of nervous system, Spinal cord
+∞
6.3
6
*
9540/0-C72.0
ICD-O-3
Neurofibroma, NOS, of spinal cord
+∞
6.3
6
*
9421/1-C72.0
ICD-O-3
Pilocytic astrocytoma of spinal cord
+∞
6.3
6
*
N76
ICPC
Neoplasm nervous system unspecified
27.0
6.2
8
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.0
6.2
17
43
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
12.7
6.1
10
8
Z3231
NOMESCO Finland
Registered nurse
1.7
6.1
148
1000
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.4
6.1
43
191
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.2
6.0
49
231
A06AD11
ATC
lactulose; oral
1.9
6.0
78
438
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
47
32
15.98
53.39
1.6
1.7
—
—
—
0
0
146
560
3.20
29.05
7.9
10.6
1.26
1.00
mmol/l
0.37
122
473
230
1218
2.54
24.03
2.3
2.4
—
—
—
0
0
234
1256
2.51
23.67
4.1
4.2
92.06
90.81
%
0.35
226
1233
337
2202
2.39
21.13
7.4
7.2
1.20
1.21
mmol/l
1.19
323
2024
358
2422
2.39
20.42
8.6
8.0
1.21
1.21
mmol/l
0.91
325
2084
339
2295
2.26
18.51
3.0
2.9
—
—
estimate
—
0
0
397
2876
2.40
18.37
6.6
5.6
6.46
6.68
mmol/l
1.56
384
2730
134
692
2.24
13.57
7.9
8.1
104.44
104.20
mmol/l
0.23
134
692
26
53
5.10
12.27
2.3
1.2
—
—
—
0
0
299
2124
1.90
12.10
5.5
5.2
35.92
35.96
g/l
0.05
284
2013
27
58
4.85
12.01
3.0
1.2
0.16
0.19
nmol/l
1.06
22
40
223
1524
1.78
9.52
2.6
2.2
193.01
191.27
u/l
0.01
218
1448
302
2264
1.75
9.23
13.1
12.9
1.21
1.22
inr
0.03
239
1870
386
3124
1.81
8.86
6.7
4.7
535.80
517.88
e6/l
—
5
51
229
1606
1.73
8.74
4.1
3.3
29.02
92.15
e6/l
0.84
181
1237
141
858
1.87
8.68
3.3
2.9
0.66
1.04
e6/l
1.24
77
459
203
1380
1.75
8.63
4.0
3.2
0.36
0.41
e6/l
0.10
161
1019
17
20
8.73
8.36
1.9
1.3
—
—
—
0
0
127
757
1.88
8.30
1.8
2.1
29.46
29.29
s
0.07
127
738
33
113
3.04
7.68
1.8
1.2
36.79
18.81
e6/l
0.37
28
83
11
6
18.67
7.62
1.2
1.2
—
—
—
0
0
434
3704
1.84
7.59
9.7
8.6
76.32
79.14
u/l
0.70
425
3512
129
795
1.82
7.51
3.4
3.0
1.88
2.32
e6/l
0.26
66
400
68
341
2.14
7.18
2.6
2.6
18.50
16.29
au/ml
0.14
14
25
349
2832
1.65
7.03
9.7
10.4
4.06
4.10
e9/l
0.13
302
2475
63
312
2.15
6.87
1.5
1.4
28.04
39.71
au/ml
—
5
24
96
559
1.87
6.65
6.7
6.4
—
—
—
0
0
420
3612
1.71
6.40
5.0
4.4
10.05
11.44
mm/h
1.39
401
3375
162
1123
1.63
6.00
3.2
2.7
3.25
5.78
e6/l
2.45
146
1021
512
4734
2.35
5.58
21.5
16.0
22.83
23.82
mg/l
0.31
440
3856
276
2193
1.52
5.50
2.6
2.5
76.84
76.39
nmol/l
0.10
258
1972
195
1439
1.55
5.45
5.2
3.9
0.00
0.01
estimate
0.78
59
502
101
639
1.71
5.25
5.1
6.3
1.04
1.02
mmol/l
0.26
95
602
38
175
2.26
4.97
5.4
4.0
1.04
1.38
mmol/l
2.64
38
170
138
959
1.59
4.94
3.3
2.8
2.44
2.45
mmol/l
0.25
125
869
125
858
1.59
4.70
3.6
3.6
0.81
0.82
mmol/l
0.14
120
817
312
2596
1.47
4.65
8.1
7.0
11.16
11.34
umol/l
0.10
303
2484
238
1885
1.47
4.54
4.1
3.8
20.39
62.51
ng/l
0.80
166
1348
315
2633
1.47
4.53
5.1
3.8
0.05
0.02
estimate
0.26
57
503
312
2605
1.46
4.50
4.8
3.8
0.00
2.99
estimate
0.50
59
543
213
1666
1.46
4.27
4.1
3.5
2.37
2.35
mmol/l
0.84
200
1514
307
2580
1.43
4.13
4.8
3.8
0.00
0.00
estimate
-0.00
59
539
58
347
1.75
3.67
1.7
1.7
—
—
—
0
0
412
3728
1.43
3.20
5.2
4.2
14.86
14.76
pmol/l
0.36
378
3415
47
279
1.75
3.08
3.0
3.3
24.75
24.14
mmol/l
0.73
47
279
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
26
128
2.08
2.96
1.8
2.5
0.43
0.37
iu/ml
0.23
11
72
194
1575
1.36
2.89
3.5
2.7
51.71
64.62
u/l
2.29
184
1461
125
943
1.42
2.89
1.4
1.3
20.85
35.01
iu/ml
1.72
34
285
481
4511
1.56
2.88
6.5
6.5
38.05
39.21
mmol/mol
2.83
457
4241
61
400
1.59
2.76
2.1
2.5
91.08
67.33
ml/min/173m2
0.54
26
176
46
281
1.70
2.74
2.4
3.7
2.14
1.83
mmol/l
0.17
28
214
115
865
1.42
2.69
1.4
1.3
3.19
12.20
u/ml
2.83
52
333
473
4434
1.51
2.68
6.3
5.2
1.82
1.91
mu/l
1.15
443
4097
159
1267
1.36
2.63
3.2
2.9
341.32
341.76
umol/l
0.02
146
1115
180
1466
1.34
2.58
3.3
3.2
794.07
1085.77
ng/l
0.97
151
1248
26
136
1.96
2.55
1.7
1.5
—
—
—
0
0
6
11
5.50
2.55
1.5
2.8
250.33
160.09
%
—
6
11
67
458
1.53
2.55
3.1
3.5
2.38
1.65
mmol/l
0.91
61
403
371
3351
1.34
2.53
4.2
3.4
45.69
48.62
u/l
0.41
364
3169
155
1237
1.35
2.53
2.5
2.2
2.97
2.94
mg/l
0.05
132
1061
143
1134
1.35
2.43
5.6
3.9
1.02
1.02
kg/l
0.05
103
768
47
301
1.61
2.37
2.5
3.5
4.23
4.47
pmol/l
1.18
42
266
10
33
3.07
2.36
1.4
1.0
—
—
—
0
0
50
327
1.58
2.32
3.0
3.0
146.09
168.04
ng/l
0.22
44
296
520
5012
1.82
2.28
14.6
12.3
26.59
26.81
u/l
0.12
513
4880
147
1189
1.32
2.16
1.3
1.3
2.22
1.26
u/ml
0.30
42
336
58
399
1.51
2.16
2.6
2.5
4.53
6.97
ug/l
0.89
53
358
203
1716
1.29
2.16
4.0
3.4
35.08
31.99
u/l
0.37
195
1628
29
167
1.78
2.16
1.4
1.5
276.23
275.04
mu/l
0.01
29
154
46
301
1.58
2.14
1.9
1.6
—
—
—
0
0
266
2329
1.28
2.14
3.0
3.0
98.61
123.68
ug/l
2.62
249
2159
484
4612
1.44
1.96
19.5
15.3
85.49
82.83
ml/min/173m2
1.94
459
4278
6
16
3.78
1.94
1.2
1.2
—
—
—
0
0
6
16
3.78
1.94
1.2
1.1
—
—
—
0
0
6
16
3.78
1.94
1.2
1.1
—
—
—
0
0
246
2153
1.26
1.92
2.3
2.1
92.34
96.39
pmol/l
0.77
136
1134
8
28
2.88
1.87
1.4
1.2
67.00
64.94
ng/l
—
8
28
6
17
3.56
1.84
1.2
1.2
—
—
—
0
0
26
154
1.72
1.79
1.2
1.4
—
—
—
0
0
93
723
1.35
1.79
2.3
2.4
22.12
22.60
%
0.13
88
682
334
3046
1.25
1.76
3.0
3.1
—
—
—
0
0
6
18
3.36
1.75
2.5
1.5
170.00
70.00
nmol/24h
—
6
18
529
5160
1.86
1.68
32.1
24.2
4.52
4.52
e12/l
0.03
523
5060
22
127
1.76
1.66
3.7
3.0
0.58
2.38
index
2.09
12
73
11
49
2.27
1.64
4.9
3.2
24.04
51.83
u/ml
0.70
11
49
224
1969
1.23
1.61
4.9
3.7
0.00
0.02
estimate
1.15
50
453
14
70
2.03
1.60
1.1
1.1
—
—
—
0
0
63
469
1.39
1.59
3.6
2.7
36.13
36.60
u/l
0.03
53
392
7
26
2.71
1.58
1.1
3.7
546.86
762.92
u/ml
—
7
26
12
57
2.13
1.56
1.4
1.1
—
—
—
0
0
167
1427
1.25
1.55
1.7
1.7
21.04
20.85
nmol/l
0.05
147
1200
135
1129
1.26
1.51
1.7
1.8
1.26
1.28
mg/l
0.03
104
871
24
147
1.66
1.50
1.3
1.2
—
—
—
0
0
104
844
1.29
1.48
2.4
2.0
—
—
—
0
0
24
148
1.65
1.46
1.3
1.2
—
—
—
0
0
7
28
2.52
1.45
1.6
1.1
—
—
—
0
0
12
59
2.06
1.44
1.3
1.1
—
—
—
0
0
5
16
3.14
1.44
1.2
1.1
—
—
—
0
0
528
5163
1.73
1.42
32.4
24.3
135.19
136.30
g/l
1.04
528
5117
10
46
2.20
1.40
1.3
1.1
—
—
—
0
0
81
641
1.31
1.40
2.5
1.9
—
—
—
0
0
0
39
0.00
1.34
0.0
2.0
—
—
—
0
0
151
1297
1.23
1.32
5.4
4.5
19.67
21.41
%
0.81
80
598
22
137
1.63
1.31
2.3
1.8
3.73
4.72
iu/l
—
9
54
10
48
2.10
1.28
1.1
1.3
—
—
—
0
0
101
836
1.26
1.24
2.4
2.5
13.38
13.21
umol/l
0.09
95
783
94
773
1.26
1.22
2.2
2.4
2.33
2.34
g/l
0.06
89
719
32
223
1.46
1.19
1.2
2.0
1.48
9.17
iu/ml
—
10
56
21
134
1.59
1.16
1.2
1.1
4.78
12.24
eliau/ml
—
5
17
35
252
1.42
1.11
1.3
1.3
—
—
—
0
0
36
261
1.41
1.11
1.0
1.0
—
—
—
0
0
26
177
1.49
1.10
2.5
2.1
1614.67
259.81
ug/l
0.60
26
165
493
4789
1.31
1.06
6.1
5.9
2.70
2.71
mmol/l
0.19
469
4446
75
613
1.26
1.04
5.3
4.9
31.07
31.79
%
0.26
58
398
62
498
1.28
0.99
4.1
3.4
—
—
—
0
0
0
29
0.00
0.98
0.0
2.2
—
—
—
0
0
0
29
0.00
0.98
0.0
1.6
—
—
—
0
0
0
29
0.00
0.98
0.0
1.6
—
—
—
0
0
16
100
1.62
0.97
3.0
3.2
7.47
8.08
pmol/l
0.14
16
100
6
27
2.24
0.93
1.0
1.0
—
—
—
0
0
109
940
1.20
0.92
4.9
4.0
179.22
367.94
ng/l
0.62
90
711
6
28
2.16
0.91
1.0
1.0
1122.83
1693.07
miu/ml
—
6
28
6
28
2.16
0.91
1.3
2.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
29
2.08
0.89
1.7
1.2
—
—
—
0
0
21
145
1.47
0.86
3.1
3.9
1.65
2.48
ratio
0.63
13
82
35
266
1.34
0.85
3.6
2.0
—
—
—
0
0
179
1621
1.16
0.84
6.3
5.3
2.16
2.27
ug/l
0.14
163
1470
10
58
1.74
0.80
1.8
1.8
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
—
—
0
0
12
74
1.64
0.78
1.0
1.2
8.50
1.32
u/ml
—
6
25
17
116
1.48
0.75
1.4
1.6
—
—
—
0
0
35
272
1.31
0.75
1.4
1.4
—
—
—
0
0
9
54
1.68
0.75
1.0
1.1
101.67
101.33
%
—
9
49
109
960
1.17
0.74
3.6
3.1
0.62
0.74
ug/l
1.39
76
602
5
25
2.01
0.73
1.2
1.3
—
—
—
0
0
12
76
1.59
0.72
1.0
1.2
2.67
4.03
u/ml
—
6
31
34
265
1.30
0.72
2.2
2.5
0.56
0.62
%
0.65
34
265
472
4600
1.19
0.71
5.7
5.1
5.90
5.95
mmol/l
0.36
442
4250
88
765
1.18
0.70
1.6
1.7
1216.07
1228.11
nmol/l
0.02
70
580
9
58
1.56
0.70
5.6
4.0
—
—
—
0
0
484
4730
1.21
0.69
5.5
5.2
4.61
4.63
mmol/l
0.20
466
4411
24
181
1.34
0.64
1.8
2.0
—
—
—
0
0
24
181
1.34
0.64
2.5
2.9
—
—
—
0
0
18
129
1.41
0.64
1.3
1.2
—
—
—
0
0
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
8.80
—
0
20
0
21
0.00
0.60
0.0
1.2
—
109.81
—
0
16
8
52
1.55
0.59
2.0
1.9
—
—
—
0
0
11
72
1.54
0.59
1.4
1.8
—
—
—
0
0
19
140
1.37
0.59
1.5
1.4
—
—
—
0
0
47
393
1.21
0.58
1.7
1.5
—
—
—
0
0
5
87
0.57
0.56
1.4
1.7
—
—
—
0
0
69
601
1.17
0.55
2.6
2.0
—
—
—
0
0
6
38
1.59
0.54
1.2
3.2
323.67
962.76
mg
—
6
38
23
178
1.31
0.54
1.5
1.7
—
—
—
0
0
6
40
1.51
0.51
1.0
1.2
111.33
100.02
pmol/l
—
6
40
41
344
1.21
0.50
1.3
1.3
83.66
119.25
u/ml
0.35
14
137
480
4714
1.15
0.48
5.4
5.1
1.46
1.45
mmol/l
0.22
455
4369
10
68
1.48
0.47
1.1
1.5
—
—
—
0
0
10
68
1.48
0.47
1.1
1.5
—
—
—
0
0
21
165
1.28
0.45
1.9
1.9
—
—
—
0
0
7
50
1.41
0.45
2.3
3.1
—
—
—
0
0
37
312
1.20
0.44
3.6
2.1
—
—
—
0
0
10
69
1.46
0.44
1.1
1.5
—
—
—
0
0
10
69
1.46
0.44
1.4
1.1
13.56
2.51
eliau/ml
—
5
28
34
403
0.83
0.44
1.8
1.9
3.35
3.46
mmol/l
0.27
24
299
0
16
0.00
0.41
0.0
1.9
—
—
—
0
0
8
61
1.32
0.39
1.3
1.4
31.84
26.42
u/l
—
8
50
10
71
1.42
0.39
1.1
1.5
—
—
—
0
0
5
35
1.43
0.39
1.8
1.6
—
—
—
0
0
69
620
1.13
0.39
1.8
1.8
1.55
1.49
%
0.12
60
544
11
80
1.38
0.38
1.8
1.4
—
—
—
0
0
11
80
1.38
0.38
1.8
1.4
—
—
—
0
0
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
9
68
1.33
0.37
1.6
2.0
9.78
10.77
mmol/l
—
9
68
10
72
1.40
0.37
1.1
1.5
—
—
—
0
0
10
72
1.40
0.37
1.1
1.5
—
—
—
0
0
9
70
1.29
0.37
1.1
1.3
—
—
—
0
0
11
81
1.37
0.36
1.4
1.5
—
—
—
0
0
10
73
1.38
0.34
1.0
1.1
—
—
—
0
0
18
146
1.24
0.32
1.3
1.3
—
—
—
0
0
7
98
0.71
0.31
4.0
2.9
—
848.56
u/ml
—
0
9
85
917
0.91
0.30
1.7
1.6
—
—
—
0
0
48
534
0.89
0.30
2.1
2.1
3.11
3.48
ratio
1.94
39
429
8
62
1.29
0.28
1.1
1.2
—
—
—
0
0
104
978
1.08
0.26
1.5
1.7
72340852.82
20441077.38
pmol/l
0.31
94
817
9
74
1.22
0.25
1.0
1.1
—
—
—
0
0
7
95
0.73
0.22
1.9
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
11.0
—
10.11
—
0
10
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
182
1757
1.05
0.21
3.5
3.4
7.63
7.76
mmol/l
0.16
160
1482
18
154
1.17
0.21
1.6
1.4
228.90
292.92
ug/g
—
10
92
15
126
1.20
0.21
1.1
1.2
—
1.00
—
0
9
15
126
1.20
0.21
1.7
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
56
520
1.09
0.20
4.3
4.4
10.47
29.05
ug/l
0.61
44
437
20
175
1.15
0.18
1.1
1.1
0.61
0.65
ratio
—
5
26
20
175
1.15
0.18
1.2
1.3
—
—
—
0
0
140
1448
0.96
0.16
4.1
3.3
0.00
0.00
estimate
0.80
51
432
172
1672
1.04
0.15
3.8
4.2
3.87
8.88
mg/mmol
3.04
117
1043
9
80
1.13
0.15
7.8
6.5
413.44
376.88
umol/l
—
9
73
11
93
1.19
0.14
1.1
1.1
5.82
1.83
u/ml
—
6
50
15
131
1.15
0.14
1.4
1.5
3498.00
14104.19
e6/l
—
9
89
12
138
0.87
0.13
2.6
1.8
—
—
—
0
0
13
148
0.88
0.12
2.5
1.8
—
—
—
0
0
20
181
1.11
0.12
1.1
1.1
1.53
1.54
g/l
0.03
20
181
21
191
1.10
0.12
1.0
1.2
0.82
0.89
g/l
0.89
21
191
14
125
1.12
0.10
1.9
1.6
—
—
—
0
0
12
106
1.14
0.10
1.6
1.7
—
—
—
0
0
14
126
1.11
0.09
1.3
1.2
—
—
—
0
0
6
54
1.11
0.09
2.8
1.9
—
—
—
0
0
12
107
1.12
0.08
1.6
1.6
—
—
—
0
0
6
73
0.82
0.07
1.5
1.8
—
—
—
0
0
214
2112
1.02
0.07
2.2
1.9
1.29
1.37
mmol/l
0.73
197
1782
15
163
0.92
0.07
1.2
1.4
169.50
258.27
miu/ml
—
6
74
15
138
1.09
0.06
1.1
1.3
—
—
—
0
0
57
587
0.97
0.06
3.1
2.1
—
—
—
0
0
452
4502
1.02
0.05
4.6
4.4
1.30
1.29
mmol/l
0.20
420
4143
12
112
1.07
0.03
2.1
1.5
—
—
—
0
0
53
540
0.98
0.02
3.0
2.0
—
—
—
0
0
22
212
1.04
0.02
3.2
3.5
25.57
25.12
mmol/l
0.23
22
204
71
701
1.01
0.02
1.5
1.5
—
—
—
0
0
11
116
0.95
0.00
1.4
1.3
—
—
—
0
0
16
154
1.04
0.00
1.6
1.5
—
—
—
0
0
11
114
0.96
0.00
1.2
1.4
—
—
—
0
0
19
186
1.02
0.00
1.9
1.6
7.50
8.48
u/ml
—
5
33
14
137
1.02
0.00
1.3
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
8
84
0.95
0.00
1.6
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
24
240
1.00
-0.00
2.0
1.4
0.14
0.27
mg/l
1.47
14
106
7
79
0.88
-0.00
1.0
1.1
1.41
1.48
g/l
—
7
72
0
6
0.00
-0.00
0.0
1.0
—
65.67
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1.17
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
0.16
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.6
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
54.60
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_SPINAL_CORD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SPINAL_CORD | 1.2 [0.99, 1.46] | 0.064 |
| Birth year | 0.996 [0.99, 1.0] | 0.315 |
During the follow-up period (1.1.1998 — 31.12.2019), 142 out of 1100 females with CD2_BENIGN_SPINAL_CORD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SPINAL_CORD | 1.165 [0.93, 1.46] | 0.183 |
| Birth year | 0.99 [0.98, 1.0] | 0.045 |
During the follow-up period (1.1.1998 — 31.12.2019), 140 out of 1023 males with CD2_BENIGN_SPINAL_CORD died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_SPINAL_CORD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.107% | 0.251% |
| 5 | 0.634% | 1.359% |
| 10 | 1.786% | 3.458% |
| 15 | 3.536% | 6.946% |
| 20 | 6.393% | 11.864% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_SPINAL_CORD – Benign neoplasm: Spinal cord
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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