Melanoma of uvea

C3_UVEAMELANOMA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

403

4. Check minimum number of events

None

403

5. Include endpoints

None

403

6. Filter based on genotype QC (FinnGen only)

365

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF6

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 365 173 192
Unadjusted period prevalence (%) 0.08 0.06 0.09
Median age at first event (years) 64.24 62.18 66.10

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
374
Matched controls
3740
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XCD10
NOMESCO Finland
Electrophysiological examination of eye
167.2
307.7
245
42
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
+∞
307.7
316
*
WX140
NOMESCO Finland
Parabulbar anesthesy
42.5
298.2
218
119
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
+∞
275.3
229
*
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
+∞
271.0
226
*
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
+∞
208.5
180
*
XCK10
NOMESCO Finland
Photography of fundus of eye
19.2
191.3
210
234
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
66.0
186.0
105
22
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
468.4
173.7
161
6
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
14.4
150.3
188
245
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
18.2
146.1
139
118
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
14.8
145.5
170
200
C69.3
ICD-10 Finland
Malignant neoplasm: Choroid
+∞
107.6
98
*
Z3229
NOMESCO Finland
Other healthcare associate professional
9.9
91.8
132
195
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
139.0
90.9
94
9
XCW99
NOMESCO Finland
Other investigative procedure of eye
8.9
88.6
144
245
8720/3-C69.3
ICD-O-3
Malignant melanoma, NOS, of choroid
+∞
86.9
80
*
WX002
NOMESCO Finland
Sedation and analgesia
6.5
71.8
185
491
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
15.8
70.8
65
49
8720/3-C69.9
ICD-O-3
Malignant melanoma, NOS, of eye, NOS
+∞
64.5
60
*
C69.39
ICD-10 Finland
Malignant tumor in chorioidea other or unspecified histology
+∞
62.3
58
*
Z2221
NOMESCO Finland
Medical doctor
4.8
50.9
194
680
ZXD10
NOMESCO Finland
Scheduled procedure
4.9
49.4
247
1059
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
16.8
48.4
42
28
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
7.2
43.2
72
120
ZXA05
NOMESCO Finland
Left side
4.1
40.5
180
684
C69.40
ICD-10 Finland
Malignant tumor of ciliary body without histology
+∞
39.3
37
*
S01ED51
ATC
timolol, combinations; ophthalmic
5.5
38.3
87
195
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
11.3
34.8
38
37
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
13.9
33.6
32
25
ZXE00
NOMESCO Finland
One hour or less
3.6
32.7
218
1047
ZXE10
NOMESCO Finland
More than one and less than three hours
3.4
30.3
207
996
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.7
30.2
128
456
ZXA00
NOMESCO Finland
Right side
3.4
29.7
175
767
8000/3-C69.3
ICD-O-3
Neoplasm, malignant of choroid
+∞
29.6
28
*
1906B
ICD-9 Finland
Malignant neoplasm of eye, Choroid[MELANOMA CHORIOIDEAE]
+∞
26.4
25
*
130
Kela drug reimbursment
Malignant tumour
4.1
24.6
79
229
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
6.5
24.4
42
71
CH2S4
NOMESCO Finland
Photography of iris
255.7
23.9
24
*
C69.42
ICD-10 Finland
Malignant tumor of ciliary melanoma
+∞
23.2
22
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
18.6
22.2
34
20
XCD20
NOMESCO Finland
Photoangiography of eye
9.0
21.3
27
32
C69.02
ICD-10 Finland
Malignant tumor in conjunctival melanoma
221.8
20.8
21
*
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
4.5
20.6
55
138
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
210.7
19.7
20
*
S01EC01
ATC
acetazolamide; systemic
7.2
19.4
30
45
C69.45
ICD-10 Finland
Melanoma of iris
+∞
18.9
18
*
3770
FHL
Placing a radiating plate on the surface of the eye with additional measures
+∞
18.9
18
*
Z51.5
ICD-10 Finland
Palliative care
3.5
18.2
71
233
XX7GT
NOMESCO Finland
Selective internal radio therapy (SIRT) with Yttrium
+∞
17.8
17
*
CF2S4
NOMESCO Finland
Photography of conjunctiva
99.9
17.7
19
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
22.2
17.5
25
12
N02AA05
ATC
oxycodone; systemic
2.7
17.5
124
572
CDC10
NOMESCO Finland
Enucleation of eye with insertion of prosthesis
+∞
16.8
16
*
H26.2
ICD-10 Finland
Complicated cataract
19.0
16.7
25
14
D31.4
ICD-10 Finland
Benign neoplasm: Ciliary body
177.6
16.6
17
*
S01ED01
ATC
timolol; ophthalmic
5.3
16.5
35
72
PC2ET
NOMESCO Finland
Extensive embolisation of lesion of liver
62.8
15.9
18
*
CDC00
NOMESCO Finland
Enucleation of eye
166.7
15.6
16
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.4
15.0
206
1274
CD2S4
NOMESCO Finland
Photography of eye
26.3
14.8
20
8
3779
FHL
Other operations in this group include disc removal
155.8
14.6
15
*
C69.99
ICD-10 Finland
Malignant tumor in unspecified localization in eye or other unspecified histology
+∞
13.6
13
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
13.5
227
1503
C69.03
ICD-10 Finland
Malignant tumor of conjunctival carcinoma
+∞
12.6
12
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
5.6
12.5
24
45
L01AX03
ATC
temozolomide; systemic
22.2
12.1
17
8
CA1ME
NOMESCO Finland
Ultrasound oculometry
22.2
12.1
17
8
Z3231
NOMESCO Finland
Registered nurse
2.3
12.0
134
742
JN4CD
NOMESCO Finland
Very extensive body CT
4.4
11.8
31
76
XCH00
NOMESCO Finland
Eye pressure measurement
3.8
11.6
37
105
A04AA02
ATC
granisetron; systemic, transdermal
3.6
11.6
41
125
JJ1AQ
NOMESCO Finland
Liver SPECT with low dose CT
+∞
11.5
11
*
C79.41
ICD-10 Finland
Secondary malignant tumor of optic nerve and eye
+∞
11.5
11
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
4.2
11.3
31
79
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
29.0
10.8
14
5
H33.2
ICD-10 Finland
Serous retinal detachment
22.2
10.8
15
7
H02AB02
ATC
dexamethasone; systemic
2.7
10.8
65
271
C69.00
ICD-10 Finland
Malignant tumor of the conjunctiva without histology
+∞
10.5
10
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
19.5
10.3
15
8
S01EA05
ATC
brimonidine; ophthalmic
5.0
10.1
22
46
A03FA01
ATC
metoclopramide; systemic, rectal
2.2
10.1
109
589
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
15.1
10.1
16
11
ZXA10
NOMESCO Finland
Bilateral
2.3
10.0
97
501
S01EA03
ATC
apraclonidine; ophthalmic
12.7
9.9
17
14
JN4BD
NOMESCO Finland
Extensive body CT
2.6
9.5
62
268
D31.2
ICD-10 Finland
Benign neoplasm: Retina
102.5
9.5
10
*
PC2DT
NOMESCO Finland
Embolisation of lesion of liver
+∞
9.4
9
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.2
9.4
25
62
180
Kela drug reimbursment
Interferon alfa
19.2
9.0
13
7
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
8.8
114
656
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.2
8.5
85
443
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
3.4
8.4
31
97
C69.20
ICD-10 Finland
Retina
+∞
8.4
8
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
7.6
64
310
A04AA01
ATC
ondansetron; systemic, rectal
2.6
7.5
45
186
S01EE01
ATC
latanoprost; ophthalmic
2.7
7.5
41
162
C69.49
ICD-10 Finland
Malignant tumor of ciliary body other or unspecified histology
+∞
7.3
7
*
C69.4
ICD-10 Finland
Malignant neoplasm: Ciliary body
+∞
7.3
7
*
QX2AN
NOMESCO Finland
Other soft tissue tumour isotope imaging
+∞
7.3
7
*
C69.90
ICD-10 Finland
Malignant tumor in unspecified localization in eye without histology
+∞
7.3
7
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.2
7.3
71
365
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
3.6
7.2
24
70
H33.0
ICD-10 Finland
Retinal detachment with retinal break
3.5
7.2
25
75
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
30.7
7.2
9
*
RS222, ,
NOMESCO Finland
9.6
6.8
13
14
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.4
6.8
17
40
A06AH03
ATC
naloxegol; oral
8.0
6.7
14
18
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
71.0
6.4
7
*
Z2446
NOMESCO Finland
Social worker
2.8
6.4
33
126
CH3S4
NOMESCO Finland
Photography of iridocorneal angle
+∞
6.3
6
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
4.2
6.1
16
39
H35.7
ICD-10 Finland
Separation of retinal layers
8.8
6.1
12
14
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
8.8
6.1
12
14

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
265
1094
5.88
58.67
6.2
3.5
28.31
34.39
u/l
1.94
259
1034
26
29
9.56
21.44
1.2
1.4
—
—
—
0
0
316
2514
2.66
11.03
15.7
8.7
90.53
80.36
u/l
1.65
306
2373
165
1120
1.85
7.62
6.9
5.9
—
—
—
0
0
62
314
2.17
6.56
1.5
1.5
—
—
—
0
0
237
1887
1.70
5.61
14.5
9.7
4.17
4.19
e9/l
0.04
214
1652
18
52
3.59
5.52
3.6
2.5
4.15
4.62
e9/l
0.27
18
52
205
1578
1.66
5.46
7.3
5.2
34.55
35.25
g/l
0.90
190
1474
153
1109
1.64
5.05
2.5
2.5
—
—
—
0
0
220
1762
1.60
4.70
9.3
7.6
1.21
1.21
mmol/l
0.08
182
1526
202
1599
1.57
4.44
8.5
7.1
1.21
1.21
mmol/l
0.01
188
1469
214
1727
1.56
4.24
11.6
15.8
1.23
1.29
inr
0.72
182
1440
36
175
2.17
4.22
2.6
3.1
18.01
1244.55
u/ml
0.87
31
149
67
410
1.77
4.05
3.9
4.5
8.28
33.85
ug/l
0.72
54
345
13
32
4.17
3.94
1.5
1.3
38.01
32.28
ng/l
0.15
13
32
242
2028
1.55
3.90
6.3
5.7
6.93
6.82
mmol/l
0.36
230
1934
147
1107
1.54
3.89
3.4
2.7
54.17
65.73
u/l
1.23
138
1024
19
72
2.73
3.79
4.5
2.7
53.11
58.44
%
0.64
19
72
138
1044
1.51
3.50
4.5
4.6
—
—
—
0
0
6
7
8.69
3.27
5.0
2.3
53.33
35.29
u/l
—
6
7
79
1105
0.64
3.12
3.5
3.6
—
—
—
0
0
154
1218
1.45
3.03
7.3
3.4
2.35
2.35
mmol/l
0.06
145
1105
267
2952
0.67
3.02
6.9
7.2
40.77
40.16
mmol/mol
0.49
250
2764
61
397
1.64
2.94
1.8
1.7
—
—
—
0
0
23
112
2.12
2.73
3.3
2.6
1.83
1.62
mg/l
0.47
23
97
261
2880
0.69
2.67
4.2
4.6
1.36
1.28
mmol/l
1.04
245
2617
49
310
1.67
2.64
1.5
1.6
—
—
—
0
0
24
121
2.05
2.62
4.8
3.2
385.90
332.89
mg/l
—
10
47
63
428
1.57
2.55
1.3
1.3
—
—
—
0
0
48
305
1.66
2.55
7.0
4.1
7.38
7.34
ph
0.99
38
210
274
2986
0.69
2.46
5.0
5.4
1.40
1.46
mmol/l
1.11
257
2727
283
3066
0.68
2.46
5.8
6.4
2.57
2.60
mmol/l
0.22
263
2808
128
1012
1.40
2.42
8.0
6.4
—
—
—
0
0
276
2999
0.70
2.37
5.2
5.5
4.47
4.51
mmol/l
0.28
258
2766
96
728
1.43
2.28
3.4
3.2
480.50
526.70
mosm/kgh2o
1.65
88
641
41
259
1.65
2.24
4.9
3.8
153.53
85.70
ng/l
1.76
36
226
135
1098
1.36
2.10
5.8
4.4
7.40
7.40
ph
0.04
98
782
50
345
1.52
1.91
1.5
1.5
—
—
—
0
0
15
72
2.13
1.89
1.7
3.3
40.80
34.89
umol/l
0.61
15
63
178
1531
1.31
1.83
3.0
2.9
—
—
estimate
—
0
0
109
1329
0.75
1.80
2.2
2.0
1.40
1.31
mmol/l
0.60
99
1087
181
1566
1.30
1.76
7.9
6.2
57.31
58.27
%
0.49
181
1488
56
409
1.43
1.63
4.2
3.3
12.35
7.39
umol/l
0.54
45
370
64
479
1.41
1.63
7.2
5.7
1.14
1.04
mmol/l
1.31
57
445
39
265
1.53
1.61
4.7
4.4
—
—
—
0
0
135
1579
0.77
1.59
2.5
2.2
98.54
96.29
pmol/l
0.17
72
827
10
44
2.31
1.56
1.1
1.3
289.20
274.09
mosm/kgh2o
—
10
32
21
125
1.72
1.47
8.0
3.6
25.85
25.06
mmol/l
0.26
21
116
141
1204
1.27
1.45
3.5
3.6
39.98
108.88
e6/l
0.67
118
937
5
16
3.15
1.44
1.0
1.1
—
—
—
0
0
197
1754
1.26
1.42
8.1
6.3
0.19
0.19
e9/l
0.05
176
1527
68
528
1.35
1.40
2.1
2.2
—
—
—
0
0
7
29
2.44
1.40
1.3
1.2
—
—
—
0
0
194
1728
1.25
1.38
8.2
6.1
2.36
1.86
e9/l
0.67
173
1528
5
17
2.97
1.36
1.6
1.5
66.60
73.76
umol/l
—
5
17
0
39
0.00
1.34
0.0
1.3
—
—
—
0
0
150
1301
1.26
1.34
2.6
2.2
—
—
—
0
0
43
576
0.71
1.28
1.3
1.3
66.06
32.64
iu/ml
0.77
16
187
16
92
1.77
1.27
1.4
1.1
—
—
—
0
0
190
1700
1.24
1.26
8.2
6.0
0.63
0.59
e9/l
1.06
170
1454
191
1711
1.24
1.25
8.2
6.0
0.04
0.04
e9/l
0.05
170
1467
39
282
1.43
1.23
2.2
3.3
257.97
213.59
ng/l
0.20
33
254
58
455
1.33
1.13
2.8
3.0
1.74
1.80
%
0.17
53
413
101
852
1.25
1.13
3.0
2.8
4.10
4.10
e6/l
0.00
96
781
92
1089
0.79
1.13
2.0
1.7
19.43
20.72
nmol/l
0.42
82
906
266
2820
0.80
1.11
6.2
5.3
1.90
1.99
mu/l
0.68
246
2560
7
32
2.21
1.08
2.1
1.8
-1.36
0.88
mmol/l
—
7
32
20
298
0.65
1.06
2.1
1.5
—
—
—
0
0
149
1319
1.22
1.05
4.2
4.4
79.58
109.30
e6/l
0.40
117
966
287
3011
0.80
1.03
5.6
5.6
6.13
6.08
mmol/l
0.28
263
2739
14
83
1.71
1.03
2.4
1.3
—
—
—
0
0
7
35
2.02
1.00
1.9
1.4
—
—
—
0
0
0
30
0.00
0.97
0.0
1.1
—
—
—
0
0
0
31
0.00
0.97
0.0
1.0
—
315.35
—
0
20
318
3051
1.28
0.94
24.6
18.5
26.35
25.60
mg/l
0.15
281
2544
7
37
1.91
0.94
1.7
3.4
3.51
4.28
nmol/l
—
7
37
10
55
1.84
0.93
3.5
2.3
34.30
32.93
pg
—
10
55
6
28
2.16
0.92
1.3
1.1
—
—
—
0
0
24
169
1.45
0.90
7.2
3.0
—
—
—
0
0
8
43
1.88
0.88
2.3
1.9
—
—
—
0
0
330
3188
1.30
0.87
20.7
13.2
27.64
25.36
u/l
1.84
322
3099
17
112
1.54
0.86
17.6
13.9
—
—
—
0
0
55
446
1.27
0.86
7.7
9.2
11.27
11.88
kpa
0.54
50
435
55
446
1.27
0.86
7.7
9.2
5.15
5.12
kpa
0.08
49
433
54
438
1.27
0.85
7.6
9.4
1.05
0.97
mmol/l
0.04
43
368
84
717
1.22
0.84
4.7
4.4
497.15
343.96
ng/l
0.16
72
594
213
1982
1.17
0.80
4.6
3.6
83.95
51.46
u/l
1.84
200
1852
0
24
0.00
0.79
0.0
1.1
—
54.64
—
0
18
6
33
1.83
0.79
1.5
3.2
1721.33
981.39
mg
—
6
33
12
74
1.64
0.79
7.1
3.3
—
—
—
0
0
18
124
1.47
0.76
5.8
3.7
1.75
3.12
ratio
—
7
68
116
1031
1.18
0.76
3.8
3.5
0.55
0.46
e6/l
0.09
97
769
54
445
1.25
0.75
7.8
9.3
7.43
7.41
ph
0.79
27
258
19
133
1.45
0.75
6.4
4.1
26.42
103.59
mg/l
1.05
12
114
19
133
1.45
0.75
6.4
4.1
16.31
66.27
mg/l
1.65
12
114
43
529
0.79
0.74
1.3
1.3
34.59
9.98
u/ml
0.65
15
195
7
38
1.86
0.74
2.3
2.2
—
—
—
0
0
122
1092
1.17
0.73
3.1
3.5
—
—
—
0
0
5
25
2.01
0.73
1.0
1.2
116.00
90.00
pmol/l
—
5
25
88
767
1.19
0.72
5.4
2.8
2.47
2.46
mmol/l
0.48
79
688
7
40
1.76
0.71
1.6
1.6
—
—
—
0
0
12
179
0.66
0.68
1.6
1.4
—
—
—
0
0
5
93
0.53
0.67
1.0
1.1
—
—
—
0
0
102
908
1.17
0.65
3.5
3.1
351.76
353.71
umol/l
0.05
87
782
68
784
0.84
0.64
3.8
3.3
0.75
0.82
ug/l
0.36
49
521
10
152
0.65
0.62
1.5
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
3.5
—
30.60
—
0
14
0
21
0.00
0.60
0.0
1.3
—
170.75
—
0
21
6
37
1.63
0.56
3.2
2.8
—
—
—
0
0
33
268
1.25
0.55
5.2
2.4
—
—
—
0
0
47
398
1.21
0.54
2.6
3.0
6.27
6.93
e9/l
0.09
40
348
46
389
1.21
0.53
3.0
3.7
7.39
7.39
ph
0.04
30
231
106
962
1.14
0.53
3.8
3.4
—
0.00
estimate
—
0
8
9
132
0.67
0.53
2.0
2.0
21.78
21.44
s
—
9
126
9
133
0.67
0.53
1.0
1.1
—
—
—
0
0
23
291
0.78
0.52
2.3
2.8
6.31
6.06
ph
0.74
18
211
109
1191
0.88
0.51
4.2
3.5
85.94
51.93
mg/l
0.60
80
788
102
926
1.14
0.50
2.3
2.3
3.10
3.07
mg/l
0.05
94
802
67
757
0.86
0.50
1.6
1.8
503.31
442.71
pmol/l
0.78
58
628
234
2235
1.13
0.50
5.6
4.8
—
3.32
—
0
8
226
2357
0.90
0.46
5.2
4.2
14.98
14.95
pmol/l
0.06
206
2113
10
69
1.46
0.44
7.4
3.6
9.16
8.16
kpa
—
10
69
10
69
1.46
0.44
7.4
3.6
4.93
4.93
kpa
—
10
69
10
69
1.46
0.44
7.4
3.6
1.44
2.34
mmol/l
—
5
42
10
69
1.46
0.44
4.7
2.9
14.19
9.42
pmol/l
—
10
69
93
850
1.13
0.42
1.4
1.3
—
—
—
0
0
113
1218
0.90
0.41
4.1
3.4
7.26
7.60
mmol/l
0.40
95
1014
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
0.46
—
0
8
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
14
181
0.76
0.39
1.4
1.3
—
—
—
0
0
5
36
1.39
0.38
1.4
1.1
—
—
—
0
0
67
741
0.88
0.38
9.4
5.2
—
—
—
0
0
36
417
0.85
0.38
1.4
1.5
—
—
—
0
0
43
375
1.17
0.38
2.8
3.7
1.02
1.84
mmol/l
0.88
36
324
10
72
1.40
0.37
1.4
1.8
—
—
—
0
0
329
3230
1.15
0.36
31.5
24.7
86.02
81.28
umol/l
0.92
323
3198
28
328
0.84
0.34
10.7
9.6
—
—
—
0
0
6
86
0.69
0.33
1.2
1.2
—
—
—
0
0
6
88
0.68
0.33
1.7
1.2
—
2.93
—
0
15
23
192
1.21
0.33
1.5
3.3
24.24
25.27
mmol/l
0.93
23
186
6
47
1.28
0.32
1.3
1.4
0.78
0.55
nmol/l
—
6
41
142
1496
0.92
0.32
2.8
2.4
75.90
77.89
nmol/l
0.39
126
1331
7
55
1.28
0.30
1.0
1.1
—
—
—
0
0
115
1219
0.92
0.30
4.9
4.2
15.81
9.15
mg/mmol
0.62
84
774
7
56
1.25
0.29
1.1
1.0
—
—
—
0
0
7
57
1.23
0.29
1.1
1.5
—
—
—
0
0
102
957
1.09
0.29
3.6
3.8
0.26
0.00
estimate
0.48
39
304
9
116
0.77
0.28
2.1
3.5
1.86
1.60
mmol/l
—
9
111
43
386
1.13
0.27
2.8
3.7
5.60
5.72
kpa
0.35
43
374
71
657
1.10
0.27
1.8
1.7
1238.85
1227.49
nmol/l
0.04
62
507
24
206
1.18
0.27
4.1
3.9
23.82
24.18
mmol/l
0.25
24
206
65
599
1.10
0.27
3.2
3.3
0.80
2.27
e6/l
2.86
35
309
5
38
1.32
0.23
3.4
4.4
264.40
347.64
umol/l
—
5
33
5
38
1.32
0.23
1.6
1.4
—
—
—
0
0
12
97
1.24
0.23
6.3
3.1
4.86
1.89
index
—
7
61
5
39
1.29
0.23
5.0
3.2
—
—
—
0
0
7
91
0.76
0.22
1.1
1.1
—
—
—
0
0
43
470
0.90
0.22
1.2
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
11.15
—
0
11
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.84
—
0
5
26
230
1.14
0.21
4.6
6.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
0.00
—
0
12
11
134
0.82
0.21
1.6
1.6
0.36
0.36
mg/l
—
5
59
6
48
1.25
0.20
2.2
1.9
4.30
4.63
mmol/24h
—
6
42
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
46
424
1.10
0.20
1.3
1.3
960.00
521.51
titre
—
9
106
106
1012
1.07
0.20
3.7
4.4
0.00
0.01
estimate
0.78
39
357
64
682
0.93
0.19
1.3
1.3
0.45
1.59
u/ml
2.23
12
180
13
109
1.20
0.19
1.6
1.6
—
—
—
0
0
7
58
1.21
0.18
1.1
1.1
—
—
—
0
0
18
157
1.15
0.17
1.5
1.3
—
—
—
0
0
5
70
0.71
0.17
1.4
1.2
27.47
18.49
u/l
—
5
59
329
3257
1.08
0.16
35.5
27.9
242.31
242.77
e9/l
0.04
323
3203
329
3257
1.08
0.16
35.4
27.9
4.40
4.44
e12/l
0.50
322
3188
329
3257
1.08
0.16
35.5
27.9
7.25
6.79
e9/l
1.56
323
3190
18
203
0.88
0.15
1.2
1.3
—
—
—
0
0
16
182
0.87
0.15
2.1
2.5
—
—
—
0
0
22
199
1.11
0.13
1.3
1.4
—
—
—
0
0
33
306
1.09
0.13
8.9
4.7
0.06
0.14
%
0.52
17
95
107
1106
0.95
0.13
2.3
2.1
209.51
206.34
u/l
0.02
100
1044
321
3181
1.06
0.13
27.9
22.6
4.02
4.00
mmol/l
0.65
314
3121
180
1762
1.04
0.13
3.9
4.4
52.00
4.09
estimate
0.71
51
398
17
189
0.89
0.12
1.1
1.2
62.58
260.17
u/ml
1.48
17
179
61
637
0.95
0.11
2.6
1.4
2.01
2.71
g/l
2.23
34
378
312
3093
1.05
0.11
21.0
16.4
—
—
—
0
0
320
3175
1.05
0.10
27.8
22.5
139.67
139.66
mmol/l
0.02
315
3117
247
2501
0.96
0.10
29.3
23.2
14.17
13.81
%
3.18
247
2477
12
106
1.14
0.10
7.4
3.4
7.39
7.41
ph
0.94
12
106
5
46
1.09
0.09
3.0
2.1
92.14
90.20
%
—
5
46
13
145
0.89
0.09
2.5
2.2
1663.54
336.03
ug/l
0.48
13
137
5
48
1.04
0.09
1.2
1.3
—
—
—
0
0
5
48
1.04
0.09
1.4
1.5
—
—
—
0
0
88
906
0.96
0.09
3.0
3.4
0.50
0.06
—
6
33
14
155
0.90
0.09
3.5
2.9
—
—
—
0
0
25
233
1.08
0.09
7.9
9.0
23.74
24.48
mmol/l
0.45
25
233
5
61
0.82
0.08
1.0
2.8
—
—
—
0
0
5
60
0.83
0.08
1.4
1.2
—
—
—
0
0
5
63
0.79
0.08
2.2
3.2
0.78
0.83
nmol/l
—
5
50
6
75
0.80
0.07
1.3
1.3
—
—
—
0
0
32
304
1.06
0.07
9.1
4.5
0.82
0.48
%
0.30
17
99
20
214
0.93
0.07
1.2
1.2
—
—
—
0
0
34
325
1.05
0.06
9.0
4.6
0.78
0.82
%
0.04
18
114
176
1781
0.98
0.06
3.9
4.4
0.00
0.01
estimate
0.50
49
364
127
1290
0.98
0.06
6.1
5.8
3.89
2.68
ug/l
0.32
112
1147
38
366
1.04
0.05
1.6
1.7
—
—
—
0
0
14
151
0.92
0.05
2.2
1.9
—
—
—
0
0
173
1749
0.98
0.05
3.9
4.4
0.02
0.00
estimate
0.49
47
387
76
776
0.97
0.05
3.4
4.7
1.02
1.02
kg/l
0.09
56
522
35
338
1.04
0.04
2.2
3.0
4.29
4.39
kpa
0.13
35
328
141
1394
1.02
0.04
3.4
3.9
6.27
6.18
ph
0.40
85
774
12
111
1.08
0.04
1.1
1.3
—
—
—
0
0
79
777
1.02
0.03
1.8
1.7
1.35
1.51
mg/l
0.29
66
620
149
1476
1.02
0.03
17.0
12.6
0.00
0.00
e9/l
0.69
125
1221
16
169
0.94
0.03
1.2
1.2
58.50
167.68
u/ml
—
6
58
42
411
1.02
0.02
1.3
1.3
—
—
—
0
0
28
287
0.97
0.01
1.9
1.5
—
—
—
0
0
134
1338
1.00
0.00
3.8
4.4
0.05
0.03
estimate
0.15
43
326
144
1439
1.00
0.00
4.7
4.3
49.96
78.47
ng/l
0.33
117
1107
10
97
1.03
0.00
1.3
1.7
—
—
—
0
0
31
313
0.99
0.00
8.8
5.1
0.07
0.18
%
0.46
15
87
11
115
0.96
0.00
5.6
4.6
—
—
—
0
0
0
7
0.00
0.00
0.0
3.1
—
7838.00
—
0
7
0
5
0.00
-0.00
0.0
3.0
—
1.80
—
0
5
6
63
0.95
-0.00
1.0
1.4
—
—
—
0
0
8
79
1.01
-0.00
1.1
1.2
—
—
—
0
0
122
1220
1.00
-0.00
3.8
3.5
1211.12
1477.18
ng/l
0.60
112
1056
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.4
—
—
—
0
0
5
50
1.00
-0.00
1.4
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
13.72
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
1.91
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.4
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
26.44
—
0
9
0
9
0.00
-0.00
0.0
1.1
—
137.89
—
0
9
5
50
1.00
-0.00
1.4
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
5
49
1.02
-0.00
1.4
1.5
—
—
—
0
0
5
57
0.88
-0.00
2.0
3.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_UVEAMELANOMA – Melanoma of uvea

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).