subcorneal pustular dermatosis: a rare, benign, chronic relapsing sterile pustular eruption typically involving the flexural sites of the trunk and proximal extremities. It most commonly affects woman aged 40 years or older.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1010 |
4. Check minimum number of eventsNone |
1010 |
5. Include endpoints |
1154 |
6. Filter based on genotype QC (FinnGen only) |
1049 |
Control definitions (FinnGen only)
- Control exclude
- L12_BULLOUS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L10-L14
- Name in latin
- Aliae morbositates bullosae
Similar endpoints
↥List of similar endpoints to
Other bullous disorders
based on the number of shared cases.
Similar with more cases:
- Bullous disorders
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7656 | 4036 | 3577 |
| Only index persons | 6569 | 3572 | 2997 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.12 | 0.10 |
| Only index persons | 0.12 | 0.13 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 48.42 | 48.66 | 48.09 |
| Only index persons | 47.51 | 47.64 | 47.37 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1049 | 611 | 438 |
| Unadjusted period prevalence (%) | 0.21 | 0.22 | 0.20 |
| Median age at first event (years) | 50.44 | 47.43 | 54.64 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1071
- Matched controls
- 10710
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L13.0
ICD-10 Finland
Dermatitis herpetiformis
10686.3
307.7
556
*
L13.9
ICD-10 Finland
Bullous disorder, unspecified
588.5
307.7
331
8
K90.0
ICD-10 Finland
Coeliac disease
37.7
307.7
346
134
J04BA02
ATC
dapsone; oral
409.3
231.8
225
7
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
8.3
204.8
331
547
69399
ICD-8 Finland
Dermatitis herpetiformis
+∞
136.4
128
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.6
83.9
390
1460
L12.0
ICD-10 Finland
Bullous pemphigoid
388.0
73.6
73
*
L13.8
ICD-10 Finland
Other specified bullous disorders
116.7
70.9
76
7
D07AC01
ATC
betamethasone; topical
3.0
69.2
553
2789
TQW80
NOMESCO Finland
Local dermatologic skincare
8.7
64.9
85
105
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.6
63.9
254
842
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
57.9
450
2186
D07AD01
ATC
clobetasol; topical
3.1
54.3
282
1093
D07AC13
ATC
mometasone; topical
2.6
46.1
414
2111
E000001, ,
ATC
2.7
44.0
302
1344
D07AB08
ATC
desonide; topical
3.3
43.7
188
645
D07AB02
ATC
hydrocortisone butyrate; topical
2.5
43.3
423
2230
E0000UV, ,
ATC
2.3
39.8
550
3342
D07BA04
ATC
hydrocortisone and antiseptics; topical
3.1
33.6
157
561
6940A
ICD-9 Finland
Bullous dermatoses, Dermatitis herpetiformis
+∞
31.4
30
*
R06AE07
ATC
cetirizine; oral
2.1
30.2
526
3384
H02AB06
ATC
prednisolone; systemic
2.1
30.1
576
3838
E000002, ,
ATC
2.7
26.2
156
633
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.8
24.0
132
513
XQ848
NOMESCO Finland
Dermatological photography
4.4
23.5
60
142
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
22.8
416
2649
L30.3
ICD-10 Finland
Infective dermatitis
3.9
22.0
67
181
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.6
21.3
74
219
QCA99
NOMESCO Finland
Other local destruction of skin of upper limb
51.1
21.2
25
5
L12.9
ICD-10 Finland
Pemphigoid, unspecified
61.3
20.9
24
*
D07BC01
ATC
betamethasone and antiseptics; topical
2.4
20.7
156
705
D09AB01
ATC
zinc bandage without supplements; topical
6.0
20.7
37
64
RD210, ,
NOMESCO Finland
5.8
19.1
35
62
D02AX
ATC
Other emollients and protectives
4.0
19.0
55
143
L20.0
ICD-10 Finland
Besnier prurigo
2.7
18.5
107
425
D07CC01
ATC
betamethasone and antibiotics; topical
2.2
17.5
164
812
D07XC01
ATC
betamethasone; topical
2.2
16.1
153
760
A46
ICD-10 Finland
Erysipelas
2.1
16.0
176
925
E000007, ,
ATC
2.8
15.8
80
296
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
6.0
15.8
28
48
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.5
15.8
38
86
L13.1
ICD-10 Finland
Subcorneal pustular dermatitis
+∞
15.7
15
*
XQ802
NOMESCO Finland
Epicutan test
3.3
15.6
61
195
R06AE09
ATC
levocetirizine; oral
2.1
15.3
167
875
D07AA02
ATC
hydrocortisone; topical
2.0
15.2
174
926
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.9
15.0
71
254
R06AX27
ATC
desloratadine; oral
1.8
14.9
311
2012
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
22.6
14.2
20
9
XQ800
NOMESCO Finland
Prick test
2.5
14.2
93
392
J01FF01
ATC
clindamycin; systemic
1.8
14.2
302
1960
J05AB01
ATC
aciclovir; systemic
1.8
13.3
253
1585
J01DB01
ATC
cefalexin; oral
1.8
13.1
878
7624
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
13.1
141
733
107
Kela drug reimbursment
Pernicious anaemia
4.6
12.9
30
66
L29.9
ICD-10 Finland
Pruritus, unspecified
3.3
12.9
48
149
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
12.8
154
832
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.2
12.8
50
160
S29
ICPC
Skin symptom/complaint other
1.8
12.6
237
1477
R06AX13
ATC
loratadine; oral
1.9
12.6
168
940
D02AE01
ATC
carbamide; topical
2.5
12.6
83
351
L04AX03
ATC
methotrexate; systemic
2.1
12.5
119
590
H02AB09
ATC
hydrocortisone; systemic
3.8
12.2
37
100
A10AA01, ,
ATC
3.6
12.1
39
110
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.4
12.1
82
352
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
3.2
12.0
47
150
A10AB01
ATC
insulin (human); parenteral
3.2
11.5
46
149
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.7
11.5
62
238
R60.0
ICD-10 Finland
Localized oedema
1.9
11.3
149
830
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
11.2
250
1629
S97
ICPC
Chronic ulcer skin
2.4
11.0
80
355
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.8
10.9
33
89
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
10.8
247
1620
J01MA02
ATC
ciprofloxacin; systemic
1.6
10.6
401
2968
D07XB05
ATC
dexamethasone; topical
3.3
10.6
39
120
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.8
10.6
52
190
A02BC02
ATC
pantoprazole; systemic
1.6
10.4
713
6000
B03BA03
ATC
hydroxocobalamin; parenteral
2.5
10.3
68
288
L04AD01
ATC
ciclosporin; systemic
4.0
10.1
28
71
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
10.1
212
1358
H04AA01
ATC
glucagon; nasal, parenteral
3.7
10.0
31
85
S02
ICPC
Pruritus
2.7
10.0
53
202
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.4
9.9
35
105
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
4.3
9.9
25
59
D05BB02
ATC
acitretin; oral
3.4
9.8
34
101
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.8
9.8
144
831
J01AA07
ATC
tetracycline; systemic
1.8
9.6
158
942
L04AX01
ATC
azathioprine; systemic
2.7
9.6
52
200
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
9.6
140
805
E000003, ,
ATC
2.6
9.6
55
218
SPAT1312
SPAT
General health counselling
1.6
9.6
325
2337
J01CF05
ATC
flucloxacillin; systemic
2.1
9.5
87
425
J01DA01
ATC
[U] cefalexin
1.5
9.4
628
5200
69300, ,
ICD-8 Finland
+∞
9.4
9
*
P01BA02
ATC
hydroxychloroquine; oral
2.1
9.4
93
468
N02AX02
ATC
tramadol; systemic, rectal
1.5
9.3
446
3449
A10AA02, ,
ATC
3.0
9.3
41
141
R06.0
ICD-10 Finland
Dyspnoea
1.6
9.3
295
2089
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
9.3
387
2909
ZY010
NOMESCO Finland
Hospital outpatient
2.4
9.2
64
278
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.9
9.1
132
756
E000006, ,
ATC
2.2
9.1
80
384
R49.08
ICD-10 Finland
Other specified dysphonia
3.4
9.1
32
96
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
9.1
441
3416
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
9.1
190
1213
L30.0
ICD-10 Finland
Nummular dermatitis
2.6
9.0
50
195
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
8.9
196
1266
L28.1
ICD-10 Finland
Prurigo nodularis
8.0
8.9
19
24
H3603, E103,
ICD-10 Finland
9.6
8.8
17
18
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.7
8.8
48
186
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
8.7
300
2160
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
8.5
367
2764
S99
ICPC
Skin disease other
3.3
8.5
32
100
N05BB01
ATC
hydroxyzine; systemic
2.2
8.5
73
347
L13
ICD-10 Finland
Other bullous disorders
20.2
8.5
12
6
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
8.4
393
3009
L12.2
ICD-10 Finland
Chronic bullous disease of childhood
+∞
8.3
8
*
R03DC03
ATC
montelukast; oral
1.7
8.3
171
1086
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
8.2
500
4022
S18
ICPC
Laceration/cut
1.5
8.2
494
3965
L30.8
ICD-10 Finland
Other specified dermatitis
2.9
8.2
39
140
L51.9
ICD-10 Finland
Erythema multiforme, unspecified
14.6
8.2
13
9
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.3
8.1
30
93
K11.70
ICD-10 Finland
Hypoptyalism
10.1
8.0
15
15
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.1
8.0
75
369
SPAT1099
SPAT
Measurement of blood pressure with Doppler ultrasound device
2.8
8.0
39
142
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
7.9
202
1353
J05AB11
ATC
valaciclovir; oral
1.7
7.8
157
988
J01DA09
ATC
[U] cefadroxil
1.5
7.8
261
1858
ZX120
NOMESCO Finland
Intravenous
1.9
7.7
99
546
H3600, E103,
ICD-10 Finland
6.0
7.7
20
34
L73.8
ICD-10 Finland
Other specified follicular disorders
4.6
7.7
18
40
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.9
7.6
97
534
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
7.6
143
885
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
7.5
126
754
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
7.5
105
596
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
7.4
225
1567
R06AX22
ATC
ebastine; oral
1.6
7.4
170
1109
L29.8
ICD-10 Finland
Other pruritus
4.1
7.4
20
50
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
7.3
423
3349
L17
ICPC
Foot/toe symptom/complaint
1.5
7.3
317
2377
D06AX01
ATC
fusidic acid; topical
1.8
7.3
102
578
135
Kela drug reimbursment
Pemphigus
+∞
7.3
7
*
L10.9
ICD-10 Finland
Pemphigus, unspecified
+∞
7.3
7
*
R03BA01
ATC
beclometasone; inhalant
1.7
7.3
138
855
SPAT1263
SPAT
Sampling
1.4
7.3
416
3287
D11AH01
ATC
tacrolimus; topical
6.3
7.3
18
29
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
7.2
138
857
H02AB04
ATC
methylprednisolone; systemic
1.7
7.2
149
947
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
7.0
119
715
B81
ICPC
Anaemia vit B12/folate deficiency
2.5
7.0
44
183
C03CA01
ATC
furosemide; systemic
1.5
7.0
302
2260
J01MA12
ATC
levofloxacin; systemic
1.6
7.0
185
1247
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
7.0
286
2118
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.9
303
2273
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
6.9
260
1893
R03AC02
ATC
salbutamol; inhalant
1.4
6.9
557
4666
UJF32
NOMESCO Finland
Coloscopy
1.5
6.8
262
1915
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
11.0
6.8
12
11
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
6.8
264
1934
N02BE01
ATC
paracetamol; systemic, rectal
1.6
6.8
929
8577
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
3.3
6.7
25
78
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
3.6
6.6
21
59
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
6.6
106
627
T89
ICPC
Diabetes insulin dependent
2.3
6.6
46
201
C07AB07
ATC
bisoprolol; oral
1.4
6.6
486
3996
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.5
6.6
39
158
M79.6
ICD-10 Finland
Pain in limb
1.4
6.6
448
3634
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
6.5
433
3496
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.5
6.5
39
159
UJD02
NOMESCO Finland
Gastroscopy
2.2
6.5
53
248
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.4
287
2160
B35.3
ICD-10 Finland
Tinea pedis
2.2
6.3
50
231
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.0
6.3
27
92
D11AX14
ATC
[U] tacrolimus
9.3
6.3
12
13
L08
ICPC
Shoulder symptom/complaint
1.5
6.3
234
1698
R52.9
ICD-10 Finland
Pain, unspecified
1.7
6.3
109
660
K29.4
ICD-10 Finland
Chronic atrophic gastritis
3.1
6.2
25
82
EKA10
NOMESCO Finland
iopsy of buccal mucosa
2.8
6.2
29
104
Z71.8
ICD-10 Finland
Other specified counselling
1.4
6.2
335
2606
Z3231
NOMESCO Finland
Registered nurse
1.5
6.1
267
1995
A10AC01
ATC
insulin (human); parenteral
1.9
6.1
79
437
A10AB05
ATC
insulin aspart; parenteral
1.9
6.1
79
437
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
6.1
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
112
48
25.94
158.02
1.4
1.1
33.64
78.33
titre
—
11
6
444
2244
2.67
51.50
2.0
1.3
6.65
1.84
u/ml
3.47
162
614
148
466
3.52
39.17
1.6
1.1
155.00
139.64
titre
0.06
19
11
365
1991
2.26
32.68
1.9
1.5
2.42
2.43
g/l
0.06
230
1212
721
5499
1.95
22.61
11.9
9.7
4.08
4.11
e9/l
0.09
643
4812
661
4937
1.89
21.64
9.0
7.5
1.21
1.21
mmol/l
0.25
590
4265
613
4499
1.85
20.91
3.8
3.1
138.64
127.11
ug/l
0.42
584
4215
586
4282
1.81
19.87
5.8
5.2
35.26
35.66
g/l
0.95
557
4031
392
2583
1.82
18.37
2.4
2.3
2.76
2.87
mg/l
0.50
343
2245
278
1657
1.92
17.82
3.1
2.6
13.20
13.08
umol/l
0.10
260
1554
591
4462
1.72
16.69
8.1
6.8
1.21
1.21
mmol/l
0.56
556
4125
569
4298
1.69
15.63
2.4
2.2
95.55
96.01
pmol/l
0.09
321
2240
571
4332
1.68
15.30
3.0
2.5
80.32
77.86
nmol/l
1.20
533
3913
850
7218
1.86
14.92
10.3
8.5
78.62
80.16
u/l
0.51
816
6849
42
108
4.01
14.78
1.2
1.3
—
—
—
0
0
152
788
2.08
14.25
3.4
2.9
10.43
10.82
g/l
0.43
141
726
251
1542
1.82
14.23
3.0
2.6
2.33
2.31
g/l
0.20
235
1442
233
1415
1.83
13.66
3.0
2.6
22.23
23.06
%
0.41
216
1334
261
1646
1.77
13.47
1.9
1.7
1188.62
1163.13
nmol/l
0.14
204
1245
127
632
2.15
13.21
1.9
1.8
1.26
1.49
g/l
0.66
120
586
822
7000
1.75
13.17
5.8
4.5
12.12
12.28
mm/h
0.12
782
6523
301
1993
1.71
13.00
1.9
1.8
449.14
23901701.72
pmol/l
1.66
249
1661
191
1137
1.83
11.81
3.7
4.3
239.05
250.88
u/l
0.49
184
1085
90
407
2.32
11.80
2.1
2.0
7.54
8.51
iu/ml
0.11
21
97
396
2874
1.60
11.68
2.0
1.7
20.10
20.39
nmol/l
0.14
356
2437
87
390
2.34
11.63
1.3
1.2
5.58
1.16
u/ml
—
5
28
62
243
2.65
11.03
1.3
1.1
49.17
4.29
eliau/ml
0.93
11
30
990
9077
2.20
10.85
24.1
16.4
22.63
24.28
mg/l
0.92
854
7488
834
7264
1.67
10.76
5.5
4.4
14.87
14.82
pmol/l
0.25
791
6649
25
55
4.63
10.75
1.8
2.4
—
—
—
0
0
70
299
2.43
10.43
1.4
1.2
112.79
2.75
u/ml
—
8
15
59
233
2.62
10.35
1.3
1.2
1.67
1.49
u/ml
—
6
16
557
4459
1.52
10.14
15.4
15.0
1.24
1.25
inr
0.07
473
3732
145
833
1.86
9.97
3.5
3.0
66.92
66.59
g/l
0.21
139
770
66
285
2.40
9.62
1.4
1.2
7.33
2.36
u/ml
0.42
11
28
262
1794
1.61
9.52
1.4
1.3
24.19
29.77
iu/ml
0.56
83
558
25
61
4.17
9.47
1.1
1.2
—
—
—
0
0
619
5111
1.50
9.41
7.1
6.8
11.95
11.50
umol/l
0.41
585
4887
66
288
2.38
9.40
1.4
1.3
2.97
8.44
u/ml
0.72
13
46
55
224
2.53
9.09
1.4
1.2
17.98
55.56
u/ml
—
5
24
435
3373
1.49
8.84
3.4
3.5
2.35
2.36
mmol/l
0.64
402
3053
88
446
2.06
8.71
1.9
1.9
1.45
1.46
g/l
0.02
74
404
413
3188
1.48
8.50
4.2
3.4
29.38
82.67
e6/l
1.77
333
2471
616
5139
1.47
8.49
5.0
4.0
0.00
0.32
estimate
0.54
130
1014
192
1249
1.65
8.49
2.2
1.9
—
—
—
0
0
724
6239
1.50
8.44
6.0
4.8
7543.31
1512.43
e6/l
0.93
16
99
364
2750
1.49
8.29
4.1
3.3
0.51
0.43
e6/l
0.12
278
2055
242
1677
1.57
8.23
1.4
1.3
6.03
11.13
u/ml
0.94
91
627
609
5097
1.45
8.07
5.1
4.0
9.11
4.53
estimate
0.20
137
1085
21
52
4.10
7.82
1.6
1.5
21.60
21.98
umol/l
0.02
21
45
601
5042
1.44
7.70
5.0
4.0
0.00
0.00
estimate
0.50
130
1061
992
9270
1.95
7.68
26.7
19.5
139.43
139.66
mmol/l
2.04
979
9095
153
962
1.69
7.67
2.7
2.1
358.23
381.09
nmol/l
0.79
145
900
931
8542
1.69
7.66
6.8
5.5
1.94
1.93
mu/l
0.15
886
7901
36
129
2.85
7.65
1.4
1.1
8.65
1.56
eliau/ml
1.33
16
53
661
5673
1.43
7.28
6.7
5.3
6.88
6.66
mmol/l
1.68
638
5403
991
9282
1.91
7.25
27.2
19.7
3.97
3.98
mmol/l
0.50
976
9090
452
3634
1.42
7.15
5.0
4.1
124.26
122.04
e6/l
0.02
350
2590
385
3013
1.43
7.05
2.7
2.2
150.24
238.94
u/l
1.86
369
2860
845
7620
1.52
7.04
28.1
20.3
13.73
13.63
%
1.39
835
7532
150
960
1.65
7.01
2.7
2.4
0.21
0.21
g/l
0.31
144
900
178
1192
1.59
6.92
2.3
1.9
—
—
—
0
0
300
2250
1.46
6.86
3.4
2.7
5.78
5.73
e6/l
0.02
274
2064
196
1351
1.55
6.71
7.5
5.9
1.05
1.05
mmol/l
0.04
189
1258
233
1669
1.51
6.68
2.5
2.0
—
—
—
0
0
320
2443
1.44
6.62
3.2
2.8
339.01
342.82
umol/l
0.26
276
2151
117
712
1.72
6.59
1.8
1.7
—
—
—
0
0
150
981
1.62
6.42
4.6
3.4
—
—
—
0
0
390
3101
1.41
6.38
3.7
2.6
71.60
87.84
u/l
0.25
365
2887
423
3413
1.40
6.34
3.8
3.4
7.21
7.50
mmol/l
0.67
368
2901
14
20
7.08
6.23
1.1
1.1
104.71
91.20
%
0.73
14
20
52
246
2.17
6.20
3.9
3.3
3.38
2.23
index
0.23
26
136
451
3690
1.38
6.17
5.2
3.9
165.81
81.84
ng/l
0.29
322
2656
404
3249
1.39
6.12
4.3
4.2
8.33
8.80
mg/mmol
0.10
265
2002
177
1231
1.52
5.78
2.1
2.4
121.68
122.67
ug/g
0.02
140
969
232
1705
1.46
5.78
3.6
3.0
1.12
1.11
e6/l
0.01
137
930
227
1665
1.46
5.71
2.9
3.4
0.81
0.82
mmol/l
0.28
221
1576
1009
9601
1.88
5.60
30.5
21.4
78.51
77.27
umol/l
0.49
1001
9497
704
6247
1.37
5.51
4.2
3.4
51.42
49.55
u/l
0.24
671
5894
355
2850
1.37
5.26
5.0
4.1
0.00
0.01
estimate
1.34
121
1000
50
250
2.05
5.21
1.5
1.5
—
—
—
0
0
121
791
1.60
5.18
2.4
2.5
6.49
7.18
ug/l
0.18
105
708
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
55
290
1.95
4.96
2.9
3.1
0.44
0.37
iu/ml
0.53
32
168
43
207
2.12
4.96
1.4
1.5
—
—
—
0
0
365
2965
1.35
4.96
3.6
3.3
1252.97
1263.06
ng/l
0.02
326
2554
15
43
3.52
4.62
1.5
3.9
626.33
758.86
u/ml
0.32
15
43
161
1154
1.47
4.51
2.8
2.9
11.76
7.99
umol/l
0.86
137
1010
10
15
6.72
4.47
1.0
1.0
—
—
—
0
0
221
1681
1.40
4.47
1.6
1.6
—
—
—
0
0
41
203
2.06
4.43
4.7
6.7
98.20
200.65
iu/ml
—
5
26
115
773
1.55
4.38
5.1
3.9
1.24
1.23
mmol/l
0.92
104
657
393
3277
1.31
4.33
3.6
3.4
32.38
32.76
u/l
0.07
374
3100
272
2150
1.36
4.33
2.1
1.8
1.30
1.24
mg/l
0.07
210
1676
11
20
5.54
4.29
1.0
1.0
—
—
—
0
0
207
1571
1.39
4.23
3.7
3.2
3.25
2.58
e6/l
0.40
110
788
1021
9835
1.82
4.20
36.3
25.1
247.03
249.81
e9/l
0.67
1003
9658
1021
9836
1.81
4.19
36.1
25.0
91.61
91.12
fl
2.68
1013
9736
1021
9838
1.81
4.15
36.2
25.0
4.39
4.47
e12/l
5.21
1001
9636
1021
9838
1.81
4.15
36.7
25.5
44.24
40.19
%
0.45
1013
9732
1021
9839
1.81
4.14
36.3
25.1
6.74
6.75
e9/l
0.09
1001
9636
55
309
1.82
4.13
1.6
1.3
—
—
—
0
0
17
57
3.01
4.13
2.3
2.5
269.00
229.16
e6/l
0.30
11
50
248
1945
1.36
4.13
2.7
2.9
2.44
2.45
mmol/l
0.65
228
1747
82
516
1.64
4.13
1.6
1.5
—
—
—
0
0
1021
9842
1.80
4.09
36.5
25.2
132.57
134.52
g/l
4.32
1013
9739
299
2416
1.33
4.08
5.0
4.2
90.34
90.33
%
0.00
293
2369
994
9518
1.62
4.04
17.1
12.4
26.63
25.86
u/l
0.52
972
9254
42
218
1.96
4.01
1.6
1.5
—
—
—
0
0
96
634
1.56
3.97
2.5
2.5
17.86
19.36
au/ml
—
5
56
127
893
1.48
3.93
9.2
7.5
10.65
9.75
mmol/l
0.65
121
861
30
140
2.18
3.80
1.1
1.1
—
—
—
0
0
155
1142
1.42
3.75
8.3
8.6
1.39
1.02
mmol/l
0.72
135
953
907
8557
1.39
3.70
7.7
6.5
40.09
39.32
mmol/mol
1.54
859
8003
59
352
1.72
3.65
3.0
2.6
0.55
1.41
g/l
1.65
54
311
137
994
1.43
3.61
5.4
3.8
1.98
1.91
mmol/l
0.08
117
852
15
51
2.97
3.58
1.3
1.0
1643.40
1586.94
miu/ml
0.05
15
51
20
80
2.53
3.56
3.3
2.5
503.80
851.14
mg
1.11
20
80
444
3837
1.27
3.53
5.0
3.9
0.04
0.03
estimate
0.22
112
871
22
93
2.39
3.50
1.6
1.3
8990.00
144469.12
e6/l
—
9
67
12
31
3.90
3.49
2.1
1.2
9.20
8.87
ug/l
0.08
12
31
31
152
2.07
3.49
1.1
1.2
3.00
6.13
u/ml
0.76
13
72
18
69
2.64
3.48
1.6
1.7
—
—
—
0
0
118
841
1.45
3.42
2.8
2.6
0.39
0.44
e6/l
0.14
113
807
511
4503
1.26
3.40
3.0
2.8
—
—
estimate
—
0
0
17
64
2.68
3.40
2.2
1.4
—
—
—
0
0
17
64
2.68
3.40
2.2
1.4
—
—
—
0
0
38
203
1.90
3.38
1.3
1.3
203.66
247.88
u/ml
0.53
22
116
237
1898
1.32
3.38
5.1
4.1
167.29
376.91
ng/l
1.81
177
1476
27
127
2.16
3.38
1.4
1.3
—
—
—
0
0
25
115
2.20
3.30
1.4
1.6
77.17
25.22
ng/l
0.53
25
115
34
177
1.95
3.27
2.0
1.4
164.11
157.23
au/ml
—
9
50
54
325
1.70
3.27
1.6
1.7
—
—
—
0
0
30
151
2.02
3.17
1.1
1.2
1.75
3.65
u/ml
0.59
12
48
48
282
1.74
3.17
2.5
2.8
184.24
191.32
%
0.19
41
271
106
753
1.45
3.14
4.7
3.3
177.34
208.99
ng/l
0.35
98
697
922
8778
1.36
3.07
5.9
5.2
6.02
5.93
mmol/l
1.33
874
8059
807
7546
1.28
3.05
30.3
21.4
331.88
332.12
g/l
0.32
802
7511
66
427
1.58
3.03
2.4
1.9
4.24
2.02
ug/l
0.77
60
389
27
133
2.06
3.03
1.0
1.1
128.77
115.87
%
0.95
22
125
279
2316
1.28
3.00
4.9
4.1
1.02
1.67
kg/l
0.50
184
1554
50
303
1.68
2.97
1.5
1.4
233.64
292.43
ug/g
0.95
26
188
15
57
2.65
2.97
2.4
2.2
336.22
616.65
e6/l
—
9
46
39
220
1.80
2.97
1.3
1.6
23985.06
638.79
e6/l
0.47
31
169
917
8737
1.34
2.92
22.0
15.8
80.07
80.71
ml/min/173m2
0.39
862
8089
19
83
2.31
2.85
1.0
1.1
—
—
—
0
0
15
59
2.56
2.79
1.2
1.0
—
—
—
0
0
42
248
1.72
2.76
1.2
1.6
—
—
—
0
0
49
303
1.65
2.72
1.4
1.5
0.01
25.08
iu/ml
—
7
48
83
579
1.47
2.72
3.4
3.7
4.38
4.59
pmol/l
1.25
71
516
13
48
2.73
2.72
2.3
1.4
—
—
—
0
0
13
48
2.73
2.72
2.3
1.4
—
—
—
0
0
122
913
1.38
2.72
2.4
2.4
35.20
36.02
u/l
0.07
105
755
14
54
2.61
2.71
1.6
1.1
0.50
0.51
ratio
—
9
32
15
60
2.52
2.71
1.1
1.0
—
—
—
0
0
55
353
1.59
2.64
1.5
1.6
27.01
11.39
u/ml
—
10
65
12
41
2.95
2.62
1.2
1.9
39.39
40.45
g/l
0.19
12
41
188
1509
1.30
2.62
2.0
2.2
29.51
29.59
s
0.07
180
1463
141
1087
1.34
2.61
10.2
7.2
—
—
—
0
0
48
299
1.63
2.60
2.8
2.4
0.02
0.00
g/l
0.49
40
260
44
269
1.66
2.57
2.3
1.6
—
—
—
0
0
616
5643
1.22
2.55
3.2
3.0
—
—
—
0
0
6
11
5.48
2.54
1.7
1.1
—
—
—
0
0
23
115
2.02
2.52
1.8
2.6
14.35
8.96
umol/l
0.36
18
80
42
255
1.67
2.52
1.8
1.6
23191.14
13891.85
e6/l
0.29
35
183
37
218
1.72
2.47
1.3
1.6
31.60
12.78
e6/l
0.30
25
162
46
288
1.62
2.46
2.3
2.9
3.36
3.58
g/l
0.49
39
277
13
51
2.57
2.45
1.2
1.0
1.11
1.07
u/l
—
5
24
83
595
1.43
2.39
3.5
4.0
1.43
1.81
mmol/l
0.45
58
454
12
46
2.63
2.36
1.1
1.1
—
—
—
0
0
31
176
1.78
2.36
1.6
1.5
—
—
—
0
0
18
84
2.16
2.35
1.1
1.2
—
—
—
0
0
18
84
2.16
2.35
1.1
1.2
—
—
—
0
0
47
300
1.59
2.34
2.0
2.7
97.37
92.19
%
0.88
40
292
19
91
2.11
2.34
1.1
1.1
—
—
—
0
0
43
269
1.62
2.32
2.1
1.7
—
—
—
0
0
47
306
1.56
2.17
2.7
2.4
0.05
0.02
g/l
0.29
42
276
103
780
1.35
2.17
2.6
2.8
60.39
65.63
ml/min/173m2
0.76
51
334
17
81
2.12
2.13
1.1
1.2
—
—
—
0
0
17
81
2.12
2.13
1.1
1.2
—
—
—
0
0
5
10
5.02
2.07
6.6
7.4
6.78
6.10
mmol/l
—
5
10
41
262
1.59
2.06
1.2
1.1
3.05
4.07
—
8
39
44
286
1.56
2.06
1.4
1.3
—
—
—
0
0
42
271
1.57
2.03
1.3
1.1
—
—
—
0
0
42
271
1.57
2.03
1.3
1.1
—
—
—
0
0
9
32
2.83
2.00
1.0
1.1
—
—
—
0
0
26
148
1.78
2.00
1.1
1.1
—
20.50
—
0
6
41
265
1.57
1.97
1.7
1.4
—
—
—
0
0
137
1099
1.28
1.94
2.0
1.8
1.59
1.50
%
0.46
111
957
9
33
2.74
1.93
1.8
2.7
0.62
0.61
mmol/l
—
9
33
928
8957
1.27
1.93
5.8
5.2
4.44
4.61
mmol/l
6.15
877
8371
886
8512
1.24
1.89
4.9
4.3
1.24
1.28
mmol/l
1.28
828
7838
310
2723
1.19
1.88
4.6
3.4
0.14
0.05
estimate
0.41
105
835
939
9086
1.27
1.84
6.4
5.9
2.59
2.68
mmol/l
2.82
882
8453
39
256
1.54
1.78
2.2
1.7
—
—
—
0
0
23
132
1.76
1.74
1.1
1.4
0.21
0.32
nmol/l
1.02
15
103
60
433
1.41
1.73
1.5
1.6
0.28
0.36
mg/l
0.43
32
190
19
103
1.86
1.72
1.1
1.2
—
—
—
0
0
103
810
1.30
1.71
5.4
4.0
125.34
84.78
ng/l
1.56
88
718
18
96
1.89
1.71
1.1
1.1
—
—
—
0
0
171
1432
1.23
1.69
1.8
1.4
—
—
—
0
0
48
334
1.46
1.68
7.3
3.8
46.00
66.28
mg/l
0.53
41
284
48
334
1.46
1.68
7.3
3.8
38.19
60.84
mg/l
0.94
41
286
44
302
1.48
1.65
1.1
1.4
192.35
245.61
miu/ml
0.64
17
145
22
127
1.75
1.65
2.5
2.4
32.95
32.69
pg
0.12
22
127
41
279
1.49
1.61
1.4
1.3
—
—
—
0
0
25
151
1.67
1.61
1.4
1.6
—
—
—
0
0
36
240
1.52
1.56
2.3
2.2
127.48
130.06
g/l
0.24
31
193
31
200
1.57
1.55
1.6
1.6
—
—
—
0
0
6
21
2.87
1.50
1.0
1.2
—
—
—
0
0
42
292
1.46
1.50
2.4
2.3
4113.37
4562.97
u/l
0.05
17
125
77
595
1.32
1.48
8.1
10.5
24.04
24.29
mmol/l
0.33
77
583
9
37
2.44
1.48
1.0
1.0
—
—
—
0
0
95
1182
0.78
1.47
6.0
4.9
32.68
32.20
%
0.17
74
797
919
8914
1.22
1.47
5.6
5.1
1.45
1.47
mmol/l
0.61
860
8268
12
59
2.05
1.44
1.3
1.2
90.08
76.92
u/l
0.27
12
50
44
312
1.43
1.43
1.9
1.6
332.59
283.33
mu/l
0.60
39
284
11
53
2.09
1.38
1.1
1.1
—
—
—
0
0
25
160
1.58
1.32
1.3
1.3
—
—
—
0
0
266
2372
1.16
1.32
2.7
2.4
—
—
—
0
0
6
24
2.51
1.30
1.2
1.1
—
—
—
0
0
28
185
1.53
1.30
1.1
1.1
1.10
2.64
u/ml
1.07
14
101
17
99
1.73
1.27
1.2
1.2
—
—
—
0
0
28
186
1.52
1.27
4.2
2.8
9.23
8.24
pmol/l
0.27
28
186
6
25
2.41
1.24
1.2
1.1
—
—
—
0
0
6
25
2.41
1.24
1.3
1.1
—
—
—
0
0
6
25
2.41
1.24
1.2
1.2
—
—
—
0
0
6
25
2.41
1.24
1.2
1.2
—
—
—
0
0
31
212
1.48
1.24
2.4
2.4
217.67
90.04
ug/min
0.35
18
124
10
49
2.05
1.22
1.1
1.8
32.10
30.18
umol/l
—
10
44
37
264
1.42
1.20
1.9
2.0
3.34
4.14
iu/l
0.25
13
108
26
173
1.52
1.18
2.1
1.9
—
—
—
0
0
20
125
1.61
1.18
1.3
1.7
—
—
—
0
0
28
190
1.49
1.17
1.6
1.4
—
—
—
0
0
28
190
1.49
1.17
1.6
1.4
—
—
—
0
0
39
283
1.39
1.16
1.5
1.4
—
—
—
0
0
91
745
1.24
1.15
1.5
1.5
—
—
—
0
0
15
87
1.73
1.15
4.0
3.1
11.86
11.95
index
—
7
61
424
3937
1.13
1.14
2.1
2.0
1.33
1.34
mmol/l
0.04
370
3297
75
602
1.26
1.13
2.0
1.7
—
—
—
0
0
59
459
1.30
1.13
2.3
2.1
—
—
—
0
0
8
40
2.01
1.12
3.4
4.2
—
—
—
0
0
15
88
1.71
1.11
1.3
1.1
99.60
106.90
pmol/l
0.32
15
88
20
128
1.57
1.09
1.5
1.5
—
—
—
0
0
14
82
1.72
1.05
1.0
1.0
273.21
287.70
mg/l
0.25
14
76
20
298
0.66
1.02
1.2
1.2
0.93
0.90
g/l
0.21
20
298
40
301
1.34
0.98
7.6
3.6
2.13
2.76
ratio
0.42
24
174
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
50
1.81
0.96
1.1
1.2
—
—
—
0
0
19
126
1.52
0.91
1.5
1.5
—
—
—
0
0
67
547
1.24
0.91
2.4
2.1
—
—
—
0
0
11
63
1.75
0.90
1.0
1.7
14.15
13.70
umol/l
0.05
11
56
43
333
1.30
0.89
5.0
3.9
1.33
1.34
mmol/l
0.03
43
326
78
650
1.22
0.88
9.1
10.2
1.50
1.34
%
0.68
78
645
82
687
1.21
0.88
1.2
1.2
76.72
129.19
u/ml
0.83
34
263
306
2828
1.11
0.87
5.0
5.6
1.88
2.50
ug/l
1.41
282
2537
19
128
1.49
0.86
1.5
1.5
—
—
—
0
0
20
286
0.69
0.85
1.3
1.2
1.41
1.56
g/l
2.19
20
286
39
300
1.31
0.85
1.3
1.3
—
—
—
0
0
15
96
1.57
0.84
1.3
1.6
—
—
—
0
0
10
57
1.76
0.83
1.3
1.2
19.80
16.28
u/l
—
10
47
10
59
1.70
0.76
1.5
1.5
—
—
—
0
0
58
478
1.23
0.75
1.3
1.3
—
—
—
0
0
38
298
1.29
0.74
1.8
1.4
—
—
—
0
0
7
39
1.80
0.72
1.3
1.4
—
—
—
0
0
26
197
1.33
0.66
1.9
3.9
240.62
1529.74
u/ml
0.52
26
185
13
86
1.52
0.66
1.0
1.0
—
—
—
0
0
7
44
1.59
0.65
1.1
1.1
1.03
1.06
ratio
—
7
38
10
62
1.62
0.65
1.3
1.7
—
—
—
0
0
17
121
1.41
0.62
1.5
1.5
—
—
—
0
0
17
121
1.41
0.62
1.5
1.5
—
—
—
0
0
14
96
1.46
0.61
1.1
1.4
1.41
1.41
nmol/l
0.00
14
85
17
122
1.40
0.60
1.5
1.5
—
—
—
0
0
10
64
1.57
0.58
2.3
1.8
95.40
100.44
ng/l
—
10
64
43
355
1.22
0.58
2.9
2.9
—
—
—
0
0
110
985
1.13
0.57
2.4
2.2
—
—
—
0
0
6
37
1.63
0.55
1.7
1.4
—
—
—
0
0
10
65
1.54
0.55
1.5
1.5
—
—
—
0
0
6
38
1.58
0.54
1.2
1.2
—
84.60
%
—
0
5
14
99
1.42
0.54
1.2
1.2
62.14
52.14
u/l
0.29
14
90
101
903
1.13
0.54
2.3
2.1
—
—
—
0
0
6
39
1.54
0.53
1.0
1.2
—
—
—
0
0
14
100
1.41
0.52
2.6
1.9
—
—
—
0
0
11
75
1.47
0.50
1.5
1.5
—
—
—
0
0
20
153
1.31
0.50
1.0
1.1
4.01
1.57
u/ml
—
10
80
27
216
1.26
0.49
1.8
1.8
201.93
208.57
pmol/l
0.15
27
205
14
103
1.36
0.45
1.7
1.3
30311.25
95384.41
e6/l
—
8
58
10
69
1.45
0.44
1.5
1.5
—
—
—
0
0
7
51
1.37
0.44
1.1
1.1
—
—
—
0
0
7
51
1.37
0.44
2.4
3.2
3.57
1.10
%
—
7
51
12
87
1.38
0.42
2.9
1.6
—
—
—
0
0
12
87
1.38
0.42
2.9
1.6
—
—
—
0
0
12
87
1.38
0.42
2.9
1.6
—
—
—
0
0
5
32
1.57
0.42
1.0
1.1
33.37
32.80
nmol/l
—
5
27
0
17
0.00
0.40
0.0
1.1
—
1.17
—
0
17
5
34
1.47
0.40
1.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.2
1.0
—
—
—
0
0
8
60
1.34
0.40
2.3
2.5
—
—
—
0
0
48
420
1.15
0.38
1.5
1.4
30.12
28.42
iu/l
0.11
40
351
5
36
1.39
0.38
1.2
1.1
—
—
—
0
0
9
67
1.35
0.38
1.2
1.3
—
—
—
0
0
9
67
1.35
0.38
1.2
1.3
—
—
—
0
0
239
2272
1.07
0.37
4.7
4.6
22.70
21.43
%
0.58
103
1103
33
281
1.18
0.37
1.7
1.8
47.55
41.35
nmol/l
0.62
33
270
85
930
0.91
0.36
2.0
2.0
3.39
3.47
ratio
0.30
72
730
6
43
1.40
0.35
1.2
2.3
—
—
—
0
0
12
91
1.32
0.34
2.9
2.0
—
—
—
0
0
21
253
0.83
0.33
1.4
1.3
—
—
—
0
0
19
155
1.23
0.32
1.1
1.1
14.20
73.32
iu/ml
—
5
28
14
110
1.28
0.31
1.6
1.3
5.88
6.53
mmol/l
0.55
14
101
21
175
1.20
0.30
1.7
1.5
1.31
1.18
ratio
0.28
16
111
21
175
1.20
0.30
1.7
1.5
1.02
0.95
ratio
0.37
16
111
21
175
1.20
0.30
1.7
1.5
1.03
1.19
ratio
0.61
16
111
7
57
1.23
0.29
2.0
1.9
6.39
7.38
mmol/l
—
7
57
19
158
1.21
0.28
1.5
1.8
—
—
—
0
0
17
141
1.21
0.26
1.1
1.1
5.46
1.99
—
5
23
16
132
1.22
0.25
1.5
1.7
—
—
—
0
0
41
368
1.12
0.25
2.5
2.0
—
—
—
0
0
63
684
0.92
0.25
1.7
1.7
3.35
3.49
mmol/l
0.50
46
495
14
114
1.23
0.25
2.1
1.5
—
—
—
0
0
10
126
0.79
0.24
1.6
1.6
61.12
56.79
ug/l
—
10
126
109
1028
1.07
0.24
3.7
4.5
6.47
22.83
ug/l
1.14
93
842
24
209
1.15
0.23
3.3
3.9
26.42
28.03
mg/l
0.11
19
146
15
125
1.20
0.22
2.4
2.4
16.80
20.31
mg/l
—
5
50
5
40
1.25
0.22
1.2
1.1
137.12
157.37
iu/ml
—
5
40
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
20
173
1.16
0.21
1.6
1.5
—
—
—
0
0
24
211
1.14
0.20
4.0
3.5
0.82
0.83
nmol/l
0.03
18
177
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
25
221
1.13
0.20
1.5
1.4
—
—
—
0
0
26
231
1.13
0.19
1.6
1.5
—
—
—
0
0
6
52
1.15
0.19
1.2
1.6
—
—
—
0
0
6
52
1.15
0.19
4.3
7.1
—
81.08
—
0
13
6
52
1.15
0.19
1.2
1.6
—
—
—
0
0
38
347
1.10
0.19
1.6
1.6
1155.97
942.80
mu/l
0.52
27
299
7
59
1.19
0.18
1.0
1.1
—
—
—
0
0
7
61
1.15
0.17
3.7
3.2
0.86
0.79
index
—
7
61
10
82
1.22
0.17
1.6
1.7
—
—
—
0
0
15
129
1.17
0.17
1.0
1.1
—
—
—
0
0
35
325
1.08
0.13
1.6
1.9
4.48
3.74
mg/l
0.17
26
245
37
346
1.07
0.12
2.0
1.8
—
—
—
0
0
164
1682
0.97
0.11
3.2
3.3
0.71
0.76
ug/l
0.24
116
1085
5
45
1.11
0.10
5.2
1.8
—
—
—
0
0
5
45
1.11
0.10
5.2
1.8
—
—
—
0
0
5
45
1.11
0.10
5.2
1.8
—
—
—
0
0
5
45
1.11
0.10
5.2
1.8
—
—
—
0
0
11
97
1.14
0.09
6.3
2.8
—
—
—
0
0
18
167
1.08
0.07
1.7
1.6
—
—
—
0
0
10
108
0.93
0.03
1.3
1.2
—
—
—
0
0
10
102
0.98
0.00
2.6
3.6
—
—
—
0
0
48
479
1.00
0.00
1.0
1.0
—
—
—
0
0
12
123
0.98
0.00
1.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
7.64
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
49
1.02
-0.00
2.6
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.45
—
0
5
8
81
0.99
-0.00
1.8
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.2
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_BULLOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_BULLOTH | 1.288 [1.11, 1.49] | < 0.001 |
| Birth year | 1.001 [0.99, 1.01] | 0.879 |
During the follow-up period (1.1.1998 — 31.12.2019), 519 out of 2922 females with L12_BULLOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_BULLOTH | 1.22 [1.06, 1.4] | 0.006 |
| Birth year | 0.991 [0.98, 1.0] | 0.041 |
During the follow-up period (1.1.1998 — 31.12.2019), 526 out of 2437 males with L12_BULLOTH died.
Mortality risk
Mortality risk for people of age
years, who have L12_BULLOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.1% | 0.243% |
| 5 | 0.847% | 1.526% |
| 10 | 2.264% | 3.883% |
| 15 | 4.52% | 7.531% |
| 20 | 7.761% | 13.074% |
Relationships between endpoints
↥Index endpoint: L12_BULLOTH – Other bullous disorders
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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