No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
365 |
4. Check minimum number of eventsNone |
365 |
5. Include endpointsNone |
365 |
6. Filter based on genotype QC (FinnGen only) |
322 |
Control definitions (FinnGen only)
- Control exclude
- N14_GLOMERULAR
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N00-N08
- Name in latin
- Haematuria recidiva et persistens
Similar endpoints
↥List of similar endpoints to
Recurrent and persistent haematuria
based on the number of shared cases.
Similar with more cases:
- Glomerulonephritis
- Glomerular diseases
- All chronic kidney diseases
- All kidney diseases
- Genitourinary diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2501 | 1150 | 1325 |
| Only index persons | 2128 | 1044 | 1084 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.03 | 0.04 |
| Only index persons | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 52.05 | 43.41 | 59.18 |
| Only index persons | 48.62 | 41.87 | 55.11 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 322 | 151 | 171 |
| Unadjusted period prevalence (%) | 0.07 | 0.05 | 0.08 |
| Median age at first event (years) | 52.94 | 43.92 | 60.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 336
- Matched controls
- 3360
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N02.9
ICD-10 Finland
Recurrent and persistent haematuria, unspecified
+∞
177.3
154
*
R31
ICD-10 Finland
Unspecified haematuria
10.5
97.1
142
218
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
+∞
60.2
56
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
26.6
56.4
40
17
KA1AE
NOMESCO Finland
Kidney ultrasound examination
17.2
47.6
41
27
A11CC03
ATC
alfacalcidol; systemic
16.5
42.3
37
25
N02.8
ICD-10 Finland
Recurrent and persistent haematuria, other
+∞
38.3
36
*
UKC02
NOMESCO Finland
Cystoscopy
4.7
37.6
116
338
N02
ICD-10 Finland
Recurrent and persistent haematuria
397.9
36.7
36
*
N02.0
ICD-10 Finland
Recurrent and persistent haematuria, minor glomerular abnormality
+∞
32.8
31
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
7.0
30.7
51
84
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
33.4
27.9
36
12
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
6.3
27.7
51
93
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
68.0
27.5
31
5
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
40.4
26.7
33
9
Z94.0
ICD-10 Finland
Kidney transplant status
101.5
26.1
28
*
N18.8
ICD-10 Finland
Other chronic renal failure
25.0
25.8
36
16
L04AA06
ATC
mycophenolic acid; systemic
26.9
24.9
34
14
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
+∞
24.3
23
*
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
+∞
24.3
23
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
22.1
21
*
N02BE, ,
ICD-10 Finland
+∞
21.1
20
*
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
+∞
21.1
20
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
82.2
21.0
23
*
127
Kela drug reimbursment
Transplant complication
31.2
20.0
26
9
A12AA04
ATC
calcium carbonate; oral
24.3
19.4
27
12
N02.2
ICD-10 Finland
Recurrent and persistent haematuria, diffuse membranous glomerulonephritis
+∞
18.9
18
*
137
Kela drug reimbursment
Uraemia requiring dialysis
200.7
18.7
19
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.1
18.5
42
92
N02.1
ICD-10 Finland
Recurrent and persistent haematuria, focal and segmental glomerular lesions
+∞
17.9
17
*
B03XA01
ATC
erythropoietin; parenteral
44.7
17.5
21
5
B03XA02
ATC
darbepoetin alfa; parenteral
20.7
17.1
25
13
R80
ICD-10 Finland
Isolated proteinuria
37.2
16.9
21
6
N02.3
ICD-10 Finland
Recurrent and persistent haematuria, diffuse mesangial proliferative glomerulonephritis
+∞
16.8
16
*
L04AD02
ATC
tacrolimus; systemic
42.4
16.5
20
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
15.7
67
233
B05DA
ATC
Isotonic solutions
167.5
15.6
16
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
167.5
15.6
16
*
C03CA01
ATC
furosemide; systemic
2.6
15.0
129
654
B05DB
ATC
Hypertonic solutions
+∞
14.7
14
*
Z49.2
ICD-10 Finland
Other dialysis
156.5
14.6
15
*
TK800
NOMESCO Finland
Hemodialysis
12.2
14.0
25
22
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
55.8
13.9
16
*
N18.0
ICD-10 Finland
End-stage renal disease
35.7
13.6
17
5
Z49.1
ICD-10 Finland
Extracorporeal dialysis
22.3
13.5
19
9
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.4
13.4
35
86
205
Kela drug reimbursment
Chronic hypertension
2.5
12.7
102
495
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
6.0
12.1
22
39
B01AB10
ATC
tinzaparin; parenteral
3.1
11.6
52
185
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
11.5
11
*
V03AE02
ATC
sevelamer; oral
124.1
11.5
12
*
N30.0
ICD-10 Finland
Acute cystitis
2.7
11.4
71
303
L04AD01
ATC
ciclosporin; systemic
13.3
11.3
19
15
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.6
10.9
72
316
V03AE01
ATC
polystyrene sulfonate; oral
18.6
10.8
16
9
H02AB04
ATC
methylprednisolone; systemic
2.7
10.8
64
265
Z49.0
ICD-10 Finland
Preparatory care for dialysis
29.1
10.8
14
5
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
22.3
10.8
15
7
N02.4
ICD-10 Finland
Recurrent and persistent haematuria, diffuse endocapillary proliferative glomerulonephritis
+∞
10.5
10
*
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
24.3
10.3
14
6
B34.9
ICD-10 Finland
Viral infection, unspecified
5.5
10.2
20
38
C09AA02
ATC
enalapril; systemic
2.5
10.2
76
352
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
41.4
10.0
12
*
J01MA02
ATC
ciprofloxacin; systemic
2.1
10.0
150
930
A41.9
ICD-10 Finland
Sepsis, unspecified
4.5
9.8
24
56
M04AA01
ATC
allopurinol; systemic
2.7
9.7
60
254
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
9.6
111
621
M05BA04
ATC
alendronic acid; oral
3.4
9.5
36
115
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
+∞
9.4
9
*
C02AC05
ATC
moxonidine; oral
4.4
9.3
24
58
A02BC01
ATC
omeprazole; systemic
2.2
9.3
105
581
L04AA01
ATC
[U] ciclosporin
16.2
9.1
14
9
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
24.8
9.0
12
5
A10BK01
ATC
dapagliflozin; oral
3.3
9.0
35
114
L04AX01
ATC
azathioprine; systemic
4.5
8.8
22
52
5997A
ICD-9 Finland
Other disorders of urethra and urinary tract, Haematuria
28.3
8.5
11
*
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
9.8
8.4
16
17
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
+∞
8.4
8
*
A02BC02
ATC
pantoprazole; systemic
2.0
8.3
231
1743
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
8.1
68
330
N02AX02
ATC
tramadol; systemic, rectal
1.9
8.0
150
985
ZX120
NOMESCO Finland
Intravenous
2.8
7.9
43
170
C08CA01
ATC
amlodipine; oral
2.0
7.9
132
835
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
7.9
93
519
C09CA01
ATC
losartan; oral
2.1
7.8
94
529
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
7.7
164
1121
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
7.5
57
265
N20.1
ICD-10 Finland
Calculus of ureter
4.0
7.4
21
55
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
11.2
7.4
13
12
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
7.3
130
834
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
7.3
82
448
J01DB01
ATC
cefalexin; oral
2.3
7.2
282
2341
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
6.3
7.2
18
30
UKB02
NOMESCO Finland
Retrograde ureteroscopy
12.4
7.1
12
10
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.9
7.0
21
57
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
7.0
103
618
R50.9
ICD-10 Finland
Fever, unspecified
2.2
6.6
62
314
K65.0
ICD-10 Finland
Acute peritonitis
10.3
6.6
12
12
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
6.4
6.5
16
26
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.7
6.5
21
60
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
71.1
6.4
7
*
RS220, ,
NOMESCO Finland
14.7
6.4
10
7
UJF32
NOMESCO Finland
Coloscopy
2.0
6.4
87
506
N03.2
ICD-10 Finland
Chronic nephritic syndrome, diffuse membranous glomerulonephritis
+∞
6.3
6
*
A12AA12
ATC
[U] calcium acetate
+∞
6.3
6
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
+∞
6.3
6
*
N04.2
ICD-10 Finland
Nephrotic syndrome, diffuse membranous glomerulonephritis
+∞
6.3
6
*
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
+∞
6.3
6
*
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
+∞
6.3
6
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
+∞
6.3
6
*
N05.9
ICD-10 Finland
Unspecified nephritic syndrome, unspecified
+∞
6.3
6
*
R11
ICD-10 Finland
Nausea and vomiting
2.5
6.3
40
171
KBV00
NOMESCO Finland
Insertion of stent into ureter
27.2
6.3
8
*
R33
ICD-10 Finland
Retention of urine
2.5
6.2
41
178
R60.0
ICD-10 Finland
Localized oedema
2.3
6.2
49
231
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
6.2
111
708
N06AX26
ATC
vortioxetine; oral
2.8
6.1
30
112
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
117
225
7.44
63.08
13.6
6.4
11.65
9.32
mmol/l
2.24
112
217
80
189
5.24
33.10
8.3
3.2
145.43
77.14
ng/l
2.38
75
164
87
264
4.10
25.78
11.2
3.2
1.41
1.75
mmol/l
0.38
78
218
30
32
10.20
25.67
1.1
1.1
—
—
—
0
0
215
1186
3.26
24.05
11.2
4.7
34.77
35.72
g/l
1.57
209
1132
226
1359
3.03
20.31
18.1
7.0
1.21
1.21
mmol/l
0.13
208
1177
139
646
2.96
20.23
8.3
2.6
4.54
6.29
e6/l
0.64
132
587
241
1514
3.09
19.75
8.1
3.8
0.00
4.98
estimate
0.50
60
326
111
466
3.06
19.25
5.0
2.2
12.98
13.38
umol/l
0.24
106
435
241
1533
3.02
18.94
8.2
3.8
0.05
0.01
estimate
0.32
58
301
172
919
2.79
18.93
9.7
3.2
90.47
122.27
e6/l
0.17
143
709
163
849
2.79
18.83
9.8
3.9
26.41
7.94
mg/mmol
2.95
136
541
237
1498
2.98
18.77
8.1
3.7
0.00
0.00
estimate
0.50
60
320
143
709
2.77
18.01
4.0
2.7
379.08
341.86
umol/l
3.57
134
631
16
0
+∞
16.81
1.3
0.0
—
—
—
0
0
37
80
5.07
16.54
2.4
3.9
45.64
28.85
mg/l
0.74
26
69
37
80
5.07
16.54
2.4
4.0
46.13
117.27
mg/l
0.48
26
69
30
54
6.00
16.33
8.2
4.5
188.80
351.80
iu/ml
—
5
5
48
132
4.08
15.90
8.9
2.8
24.67
24.56
mmol/l
0.07
48
126
162
908
2.51
15.27
8.1
3.1
7.65
8.00
mmol/l
0.49
144
769
189
1144
2.49
14.98
8.0
3.6
0.02
0.01
estimate
0.15
52
272
198
1234
2.47
14.58
15.1
6.3
1.21
1.21
mmol/l
0.15
192
1137
33
74
4.84
14.11
2.4
3.5
1.41
2.93
ratio
0.70
16
39
53
173
3.45
13.63
6.7
2.7
128.00
130.51
g/l
0.32
53
167
134
719
2.44
13.52
2.5
2.1
2.77
2.82
mg/l
0.11
122
621
30
65
4.97
13.34
1.8
1.3
—
—
—
0
0
140
782
2.35
12.75
9.3
3.2
0.25
0.36
e6/l
0.85
113
578
196
1263
2.32
12.73
19.8
13.7
1.22
1.25
inr
0.37
178
1051
12
0
+∞
12.58
6.0
0.0
—
—
—
0
0
75
314
2.79
12.53
7.9
9.4
0.50
0.91
mmol/l
0.28
58
259
22
19
12.30
12.50
4.1
4.2
1552.36
549.42
mg
1.34
22
19
28
62
4.84
12.13
1.6
1.2
277.59
226.00
u/ml
0.30
22
36
28
62
4.84
12.13
1.8
1.2
154.50
157.08
au/ml
—
8
18
24
48
5.31
11.65
7.3
2.3
9.30
8.72
pmol/l
0.10
24
48
47
158
3.30
11.48
4.2
2.9
1.70
1.51
mmol/l
0.11
32
120
28
67
4.47
11.04
1.5
1.2
—
—
—
0
0
154
944
2.17
10.75
5.7
3.1
2.33
2.35
mmol/l
1.07
143
862
72
319
2.60
10.65
8.3
9.3
11.38
12.09
kpa
0.51
66
309
72
319
2.60
10.65
8.2
9.3
5.00
5.08
kpa
0.31
66
307
183
1209
2.13
10.41
3.5
2.4
72.27
74.83
nmol/l
0.65
173
1088
246
1827
2.29
10.32
10.6
4.6
184.40
702.77
e6/l
—
10
30
142
861
2.12
10.02
7.3
3.1
0.03
0.01
estimate
0.21
40
255
225
1636
2.14
9.61
16.4
10.2
4.34
4.10
e9/l
0.81
209
1434
91
469
2.29
9.58
6.6
3.0
1.64
0.99
e6/l
0.53
58
246
197
1365
2.07
9.56
5.0
3.0
131.38
114.80
ug/l
0.64
185
1277
46
179
2.82
8.69
9.1
7.4
23.71
24.76
mmol/l
1.14
46
179
85
442
2.24
8.67
6.8
3.1
1.86
2.15
e6/l
0.18
49
223
133
829
2.00
8.37
8.1
3.9
0.02
0.00
estimate
0.38
51
298
267
2128
2.24
8.29
14.5
8.0
77.21
78.27
u/l
0.15
258
2017
48
202
2.61
7.78
4.1
2.6
53.71
69.20
ml/min/173m2
1.14
24
87
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
25
74
3.57
7.40
3.5
2.3
0.28
0.31
iu/ml
0.25
12
40
66
332
2.23
7.20
2.6
1.9
—
—
—
0
0
86
482
2.05
7.11
2.6
1.9
—
—
—
0
0
79
432
2.08
6.96
2.1
1.6
1356.64
1197.81
nmol/l
0.63
63
330
11
9
12.58
6.62
1.0
1.0
—
—
—
0
0
91
534
1.97
6.56
2.2
1.7
420.51
25215949.75
pmol/l
0.79
79
464
67
359
2.08
6.19
2.5
1.8
—
—
—
0
0
16
39
4.26
6.16
1.1
1.1
—
—
—
0
0
32
124
2.75
6.08
2.2
2.2
3.95
7.97
iu/ml
—
8
37
105
662
1.85
6.03
8.6
3.8
1.02
1.02
kg/l
0.81
79
427
20
63
3.31
5.41
3.5
2.2
196.99
93.41
ug/min
0.66
14
36
54
281
2.10
5.36
4.8
3.3
—
—
—
0
0
9
8
11.52
5.32
3.3
1.3
188.44
59.78
ng/l
—
9
8
127
874
1.73
5.31
2.8
2.1
141.93
296.06
u/l
1.10
121
842
16
44
3.77
5.27
1.7
1.3
—
—
—
0
0
5
0
+∞
5.22
1.6
0.0
1.80
—
%
—
5
0
161
1188
1.68
5.17
2.5
2.1
90.48
94.70
pmol/l
0.65
97
640
119
812
1.72
5.09
1.9
1.7
17.21
20.93
nmol/l
2.84
106
686
23
82
2.94
5.09
1.7
1.4
—
—
—
0
0
149
1082
1.68
5.05
5.6
3.9
41.44
40.50
ng/l
0.03
115
765
41
197
2.23
4.96
1.9
1.6
—
—
—
0
0
104
690
1.73
4.89
2.9
2.4
—
—
—
0
0
305
2727
2.28
4.77
36.6
15.6
21.70
23.55
mg/l
0.57
284
2231
18
58
3.22
4.71
1.7
1.5
—
—
—
0
0
174
1332
1.64
4.69
3.9
2.8
—
—
estimate
—
0
0
138
1005
1.63
4.49
5.4
3.1
28.76
33.42
u/l
0.93
131
960
100
671
1.70
4.46
1.9
1.7
0.84
1.40
mg/l
2.55
76
523
21
80
2.73
4.15
1.7
1.5
—
—
—
0
0
21
81
2.70
4.06
1.4
1.2
—
—
—
0
0
21
82
2.67
3.97
1.8
1.5
—
—
—
0
0
14
45
3.20
3.69
1.7
1.2
—
—
—
0
0
8
12
6.80
3.69
2.8
4.2
10.36
10.78
kpa
—
8
12
8
12
6.80
3.69
2.8
4.2
4.79
4.78
kpa
—
8
12
17
62
2.83
3.64
1.5
1.4
—
—
—
0
0
24
114
2.19
3.02
1.6
1.3
—
—
—
0
0
15
57
2.71
3.00
1.6
1.4
—
—
—
0
0
10
26
3.93
3.00
1.9
1.2
—
—
—
0
0
16
63
2.62
3.00
1.6
1.5
—
—
—
0
0
241
2104
1.51
2.93
6.1
4.0
15.39
11.10
mm/h
3.24
233
1965
23
109
2.19
2.92
1.3
2.5
4.15
4.33
g/l
0.43
23
101
23
109
2.19
2.92
1.3
2.5
3.92
3.56
g/l
0.65
23
101
23
109
2.19
2.92
1.3
2.5
7.02
7.41
g/l
0.59
23
101
111
834
1.49
2.90
4.0
3.3
3134.62
1300.28
ng/l
1.23
97
704
9
23
3.99
2.79
1.7
1.6
—
—
—
0
0
5
6
8.43
2.76
1.2
1.0
—
—
—
0
0
22
105
2.17
2.75
1.4
2.6
2.86
2.99
g/l
0.23
22
97
12
40
3.07
2.72
2.8
2.3
32.33
32.75
pg
0.13
12
40
11
35
3.21
2.67
8.7
3.8
6.53
6.66
mmol/l
0.07
11
30
7
15
4.74
2.61
2.7
1.2
12.29
13.40
u/l
—
7
15
72
508
1.53
2.50
1.1
1.3
13.76
8.21
u/ml
0.19
27
209
7
16
4.44
2.48
7.3
3.4
0.86
0.81
index
—
7
16
12
45
2.73
2.48
1.5
1.4
—
—
—
0
0
281
2568
1.58
2.47
5.0
4.2
1.36
1.26
mmol/l
1.55
265
2373
74
528
1.51
2.44
6.6
3.6
3595.00
318.05
ng/l
0.46
55
401
6
12
5.07
2.41
1.2
1.0
1745.50
1491.25
miu/ml
—
6
12
75
542
1.49
2.32
4.8
3.0
2.47
2.44
mmol/l
0.85
63
496
7
18
3.95
2.26
1.7
1.2
—
—
—
0
0
5
9
5.62
2.22
4.8
3.0
0.56
0.60
mmol/l
—
5
9
237
2113
1.41
2.18
4.6
4.3
14.64
14.72
pmol/l
0.19
217
1946
13
55
2.42
2.15
1.6
1.5
—
—
—
0
0
28
161
1.81
2.13
1.8
1.4
—
—
—
0
0
285
2636
1.53
2.11
32.7
15.0
72.09
83.81
ml/min/173m2
9.92
271
2436
19
96
2.04
2.10
1.4
2.4
10.35
10.36
g/l
0.00
19
87
28
162
1.79
2.09
1.9
1.7
—
—
—
0
0
6
15
4.05
2.04
1.0
1.4
—
—
—
0
0
6
15
4.05
2.04
1.0
1.4
—
—
—
0
0
9
32
2.86
2.01
1.6
1.1
—
—
—
0
0
19
99
1.97
1.94
3.7
2.7
—
—
—
0
0
293
2738
1.55
1.94
6.4
5.5
2.56
2.71
mmol/l
2.38
280
2552
22
122
1.86
1.89
2.0
2.2
2499.09
5031.74
u/l
—
7
49
13
59
2.25
1.86
5.7
2.1
4.86
4.96
kpa
0.26
13
59
6
17
3.57
1.84
1.8
1.2
—
—
—
0
0
5
12
4.21
1.83
1.4
2.4
10.60
13.42
%
—
5
12
7
23
3.09
1.81
1.4
1.2
0.11
1.13
promille
—
7
18
289
2702
1.50
1.80
5.9
4.9
4.41
4.59
mmol/l
2.57
276
2524
288
2691
1.49
1.80
5.8
4.8
1.35
1.43
mmol/l
3.39
274
2504
14
67
2.14
1.78
2.2
1.4
—
—
—
0
0
280
2606
1.45
1.75
6.0
4.8
5.91
5.89
mmol/l
0.08
264
2411
8
30
2.71
1.73
1.4
1.8
—
—
—
0
0
20
112
1.84
1.68
2.1
1.9
—
—
—
0
0
16
83
1.97
1.67
1.5
2.6
0.00
0.00
g/l
-0.00
16
78
14
69
2.07
1.67
1.6
1.4
208.00
291.47
ug/g
—
7
41
6
19
3.20
1.67
2.5
2.8
133.50
138.63
nmol/l
—
6
19
72
550
1.39
1.65
1.2
1.3
63.62
30.62
iu/ml
0.40
19
165
6
20
3.04
1.59
1.8
1.3
—
—
—
0
0
8
33
2.46
1.54
1.4
1.8
—
—
—
0
0
15
80
1.92
1.47
1.2
1.4
—
—
—
0
0
7
28
2.53
1.46
1.0
1.5
—
—
—
0
0
15
81
1.89
1.42
1.0
1.3
—
—
—
0
0
7
29
2.44
1.40
1.4
1.2
—
—
—
0
0
85
686
1.32
1.37
1.2
1.3
0.55
1.62
u/ml
2.15
22
187
18
105
1.75
1.36
2.8
1.9
—
—
—
0
0
11
54
2.07
1.34
2.9
1.4
—
—
—
0
0
11
54
2.07
1.34
2.9
1.4
—
—
—
0
0
119
1013
1.27
1.28
5.6
5.7
3.53
2.67
ug/l
0.42
108
920
13
70
1.89
1.25
2.5
1.3
—
—
—
0
0
5
19
2.66
1.22
2.0
1.7
—
—
—
0
0
49
371
1.38
1.20
2.8
2.9
10.77
7.30
umol/l
0.41
41
322
5
20
2.52
1.15
1.0
1.7
—
—
—
0
0
8
40
2.02
1.13
1.0
1.2
—
—
nmol/l
—
0
0
200
1830
1.23
1.07
3.5
3.3
—
—
—
0
0
12
67
1.82
1.06
1.7
1.5
—
—
—
0
0
268
2536
1.28
1.04
8.8
6.1
39.60
38.99
mmol/mol
0.49
256
2388
7
35
2.02
1.00
1.3
1.4
—
—
—
0
0
16
100
1.63
0.98
2.5
1.7
—
—
—
0
0
71
586
1.27
0.97
1.5
1.6
—
—
—
0
0
12
71
1.72
0.90
1.1
1.4
—
—
—
0
0
17
111
1.56
0.89
1.4
1.3
112.60
262.14
miu/ml
—
5
54
265
2521
1.24
0.87
6.0
5.2
1.79
1.90
mu/l
0.78
247
2337
20
138
1.48
0.83
2.5
2.6
32.35
49.43
u/ml
0.35
20
133
6
34
1.78
0.76
3.0
3.4
—
—
—
0
0
9
55
1.65
0.74
1.3
1.6
—
—
—
0
0
7
38
1.86
0.74
1.1
1.2
—
—
—
0
0
5
26
1.94
0.71
1.6
1.8
—
—
—
0
0
5
26
1.94
0.71
1.6
1.8
—
—
—
0
0
5
26
1.94
0.71
1.6
1.8
—
—
—
0
0
23
174
1.35
0.62
3.2
3.8
4.68
4.55
pmol/l
0.29
23
157
0
20
0.00
0.60
0.0
1.1
—
40.68
—
0
12
0
20
0.00
0.60
0.0
1.1
—
545.38
—
0
13
0
22
0.00
0.59
0.0
1.2
—
10.23
—
0
22
5
87
0.57
0.57
2.8
1.5
—
—
—
0
0
6
37
1.63
0.56
2.7
2.9
6.87
3.71
nmol/l
—
6
37
6
40
1.51
0.52
1.0
1.1
—
19.29
—
0
7
6
40
1.51
0.52
1.0
1.2
—
—
—
0
0
15
201
0.73
0.50
2.3
1.9
—
—
—
0
0
7
46
1.53
0.48
1.9
1.4
—
—
—
0
0
10
68
1.49
0.47
1.3
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
193.85
—
0
17
5
34
1.48
0.40
1.2
1.4
—
—
—
0
0
5
35
1.43
0.39
1.2
1.4
—
—
—
0
0
5
35
1.43
0.39
1.2
1.4
—
—
—
0
0
5
36
1.39
0.38
1.0
1.0
—
—
—
0
0
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
19
234
0.80
0.37
2.1
2.0
—
—
—
0
0
204
1960
1.10
0.37
4.8
3.2
44.51
46.18
u/l
0.17
194
1866
33
283
1.18
0.36
2.8
4.4
3.35
8.91
ug/l
2.03
25
233
12
91
1.33
0.34
1.6
1.5
—
—
—
0
0
89
823
1.11
0.34
5.2
4.8
23.87
21.96
%
0.48
46
405
25
292
0.84
0.30
24.6
7.2
—
—
—
0
0
27
233
1.17
0.28
1.6
1.4
—
—
—
0
0
8
64
1.26
0.27
1.9
1.9
—
—
—
0
0
11
88
1.26
0.23
1.4
1.2
—
—
—
0
0
7
92
0.76
0.22
1.3
1.4
—
—
—
0
0
38
419
0.90
0.22
1.6
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
8.84
—
0
10
0
12
0.00
0.21
0.0
1.7
—
65.80
—
0
12
11
89
1.24
0.21
1.4
1.2
—
—
—
0
0
6
48
1.25
0.20
3.2
2.1
3.20
4.98
umol/l
—
6
36
18
159
1.14
0.15
2.2
1.5
0.28
0.32
mg/l
—
8
74
8
97
0.82
0.14
1.5
1.8
196.38
220.76
pmol/l
—
8
90
17
154
1.11
0.10
1.3
1.3
—
—
—
0
0
6
56
1.07
0.08
1.3
1.6
54.17
51.47
ug/l
—
6
56
115
1127
1.03
0.07
2.1
1.9
1.33
1.38
mmol/l
0.31
92
958
8
76
1.05
0.07
1.9
1.6
—
—
—
0
0
24
251
0.95
0.04
1.5
1.9
3.27
3.51
mmol/l
0.95
15
185
63
619
1.02
0.03
3.7
3.3
1.63
0.84
ug/l
0.53
42
409
13
137
0.95
0.01
1.2
1.0
—
—
—
0
0
11
109
1.01
0.00
1.5
1.5
—
—
—
0
0
37
369
1.00
0.00
1.9
2.0
—
—
—
0
0
12
117
1.03
0.00
1.0
1.1
1.00
0.89
g/l
0.77
12
117
34
337
1.01
0.00
1.7
2.1
3.38
3.56
ratio
0.46
28
270
12
115
1.05
0.00
1.0
1.1
1.59
1.54
g/l
0.26
12
115
40
404
0.99
0.00
1.9
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
17.20
—
0
6
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
21
210
1.00
-0.00
1.2
1.3
177.16
136.71
u/ml
—
10
80
Mortality – FinRegistry
↥Association
Association between endpoint N14_RECURANDPERHEAMATUR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RECURANDPERHEAMATUR | 2.32 [1.83, 2.94] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.11 |
During the follow-up period (1.1.1998 — 31.12.2019), 187 out of 1005 females with N14_RECURANDPERHEAMATUR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RECURANDPERHEAMATUR | 2.256 [1.73, 2.94] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 422 out of 1118 males with N14_RECURANDPERHEAMATUR died.
Mortality risk
Mortality risk for people of age
years, who have N14_RECURANDPERHEAMATUR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.215% | 0.347% |
| 5 | 1.295% | 2.358% |
| 10 | 3.217% | 5.811% |
| 15 | 5.868% | 11.113% |
| 20 | 10.82% | 18.533% |
Relationships between endpoints
↥Index endpoint: N14_RECURANDPERHEAMATUR – Recurrent and persistent haematuria
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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