Lichen simplex chronicus

L12_LICHENSIMPLEX

lichen disease: a long-term skin condition that mainly affects the skin of the genitals. It usually causes itching and white patches to appear on the affected skin.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L28.0
  • Hospital discharge: ICD-9 6983B|697X
  • Hospital discharge: ICD-8 6983
  • Cause of death: ICD-10 L28.0
  • Cause of death: ICD-9 6983B|697X
  • Cause of death: ICD-8 6983

2 out of 7 registries used, show all original rules.

1485

4. Check minimum number of events

None

1485

5. Include endpoints

None

1485

6. Filter based on genotype QC (FinnGen only)

1340

Control definitions (FinnGen only)

Control exclude
L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L28
Name in latin
Lichen simplex chronicus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8813 4491 4275
Only index persons 7913 4095 3818
Unadjusted period prevalence (%)
Whole population 0.12 0.13 0.12
Only index persons 0.15 0.15 0.15
Median age at first event (years)
Whole population 53.53 54.18 52.91
Only index persons 52.84 53.38 52.26

-FinnGen-

Key figures

All Female Male
Number of individuals 1340 743 597
Unadjusted period prevalence (%) 0.27 0.26 0.27
Median age at first event (years) 54.01 53.16 55.08

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1384
Matched controls
13840
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D07AD01
ATC
clobetasol; topical
14.3
307.7
780
1146
L30.9
ICD-10 Finland
Dermatitis, unspecified
9.8
307.7
627
1074
D07AC01
ATC
betamethasone; topical
9.3
307.7
996
2989
D09AB01
ATC
zinc bandage without supplements; topical
68.5
307.7
262
47
L28.0
ICD-10 Finland
Lichen simplex chronicus
16384.0
307.7
1301
7
D07AC13
ATC
mometasone; topical
7.1
298.8
807
2269
E0000UV, ,
ATC
6.3
244.5
930
3405
TQW80
NOMESCO Finland
Local dermatologic skincare
26.2
209.5
148
63
D07BC01
ATC
betamethasone and antiseptics; topical
6.9
208.1
396
763
L20.0
ICD-10 Finland
Besnier prurigo
+∞
193.4
181
*
L30.3
ICD-10 Finland
Infective dermatitis
22.4
192.8
145
72
XQ802
NOMESCO Finland
Epicutan test
26.4
188.1
132
55
E000001, ,
ATC
5.4
184.0
483
1241
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.4
177.7
293
482
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
5.7
163.1
369
824
D07AB02
ATC
hydrocortisone butyrate; topical
4.0
138.3
619
2319
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
43.4
130.1
78
19
D07CC01
ATC
betamethasone and antibiotics; topical
4.9
126.3
338
858
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
6.1
113.4
219
415
D07AB08
ATC
desonide; topical
5.4
109.7
245
530
L28.1
ICD-10 Finland
Prurigo nodularis
278.0
102.2
103
*
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
+∞
101.3
96
*
E000002, ,
ATC
4.8
93.5
236
563
L28
ICD-10 Finland
Lichen simplex chronicus and prurigo
24.6
82.8
59
25
D07XC01
ATC
betamethasone; topical
4.0
82.6
276
811
D02AE01
ATC
carbamide; topical
5.7
82.2
166
325
L30.0
ICD-10 Finland
Nummular dermatitis
8.7
81.6
107
132
D07BA04
ATC
hydrocortisone and antiseptics; topical
4.6
77.1
204
502
A46
ICD-10 Finland
Erysipelas
3.4
75.3
327
1140
L20.8
ICD-10 Finland
Other atopic dermatitis
+∞
69.4
66
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
5.8
65.0
124
229
L30.8
ICD-10 Finland
Other specified dermatitis
10.0
62.6
73
77
R06AE07
ATC
cetirizine; oral
2.4
57.6
700
4078
69830
ICD-8 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus
+∞
56.6
54
*
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.7
55.7
406
1857
D02AX
ATC
Other emollients and protectives
8.8
54.9
70
83
E000006, ,
ATC
4.5
54.7
141
337
E000003, ,
ATC
6.0
53.9
99
176
N05BB01
ATC
hydroxyzine; systemic
4.6
53.3
135
318
XQ848
NOMESCO Finland
Dermatological photography
6.9
51.8
82
125
D05AX52
ATC
calcipotriol, combinations; topical
4.5
51.2
131
311
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
7.8
50.4
71
95
D07AA02
ATC
hydrocortisone; topical
3.2
50.1
226
793
L20
ICD-10 Finland
Atopic dermatitis
+∞
49.3
47
*
XQ800
NOMESCO Finland
Prick test
4.2
48.1
135
344
L43.9
ICD-10 Finland
Lichen planus, unspecified
7.4
47.8
71
101
D05BB02
ATC
acitretin; oral
7.4
47.3
70
99
E000007, ,
ATC
5.0
47.2
106
226
L43.8
ICD-10 Finland
Other lichen planus
8.1
45.4
62
80
L29.9
ICD-10 Finland
Pruritus, unspecified
7.2
44.8
68
99
D07AC14
ATC
methylprednisolone aceponate; topical
4.7
44.1
106
239
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
+∞
42.9
41
*
6983B
ICD-9 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus[NEURODERMATITIS CIRCUMSCRIPTA]
+∞
42.9
41
*
H02AB06
ATC
prednisolone; systemic
2.1
41.0
722
4688
R06AX27
ATC
desloratadine; oral
2.2
40.1
452
2460
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.7
36.7
225
926
L29.8
ICD-10 Finland
Other pruritus
11.1
36.5
39
36
L28.2
ICD-10 Finland
Other prurigo
100.3
35.9
39
*
S29
ICPC
Skin symptom/complaint other
2.3
34.0
326
1644
R06AE09
ATC
levocetirizine; oral
2.5
31.5
231
1033
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
+∞
29.3
28
*
J01DA01
ATC
[U] cefalexin
1.9
29.3
891
6685
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
26.9
212
975
J01CE08
ATC
benzathine benzylpenicillin; parenteral
9.3
26.6
32
35
S87
ICPC
Dermatitis/atopic eczema
6.3
26.4
45
74
S02
ICPC
Pruritus
4.1
26.3
74
188
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
5.6
26.1
50
92
D07XB05
ATC
dexamethasone; topical
5.1
25.5
54
109
J01DB01
ATC
cefalexin; oral
2.2
25.4
1165
9790
D11AH01
ATC
tacrolimus; topical
91.8
24.7
27
*
J01FF01
ATC
clindamycin; systemic
1.9
23.9
401
2446
D07CB01
ATC
triamcinolone and antibiotics; topical
5.6
23.8
45
82
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.4
23.1
84
255
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
233.7
22.7
23
*
L50.3
ICD-10 Finland
Dermatographic urticaria
6.3
22.4
38
62
C03CA01
ATC
furosemide; systemic
1.8
22.2
408
2553
L04AX03
ATC
methotrexate; systemic
2.4
21.7
164
738
E000004, ,
ATC
6.2
21.6
37
61
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
20.5
505
3429
S76
ICPC
Skin infection other
3.0
20.4
95
335
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
20.2
673
4957
H02AB04
ATC
methylprednisolone; systemic
2.1
19.9
214
1110
R06.0
ICD-10 Finland
Dyspnoea
1.8
19.9
392
2492
S97
ICPC
Chronic ulcer skin
2.7
19.8
111
432
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
74.6
19.7
22
*
R03AC02
ATC
salbutamol; inhalant
1.7
19.6
753
5744
SPAT1263
SPAT
Sampling
1.7
19.4
565
4000
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
19.0
192
972
D01AE15
ATC
terbinafine; topical
2.5
18.9
120
497
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
6.0
18.8
33
56
L43.0
ICD-10 Finland
Hypertrophic lichen planus
13.8
18.3
31
23
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
14.6
18.1
30
21
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
18.1
577
4164
L43
ICD-10 Finland
Lichen planus
6.4
18.1
30
48
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
18.0
200
1048
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
18.0
408
2687
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
+∞
17.7
17
*
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
96.3
17.6
19
*
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.1
17.5
172
861
E66.01
ICD-10 Finland
Obesity due to excess calories
2.2
17.4
155
746
N02AX02
ATC
tramadol; systemic, rectal
1.6
17.3
598
4391
S21
ICPC
Skin texture symptom/complaint
2.0
17.2
211
1146
UJF32
NOMESCO Finland
Coloscopy
1.7
16.9
365
2365
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
16.9
269
1593
M79.7
ICD-10 Finland
Fibromyalgia
3.3
16.9
65
205
WQ020, ,
NOMESCO Finland
+∞
16.7
16
*
M79.6
ICD-10 Finland
Pain in limb
1.6
16.5
614
4573
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
16.2
269
1611
L29.2
ICD-10 Finland
Pruritus vulvae
6.1
16.1
28
47
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
16.0
165
839
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
3.2
15.8
62
198
L04AD01
ATC
ciclosporin; systemic
4.7
15.7
36
78
D11AX14
ATC
[U] tacrolimus
+∞
15.7
15
*
WQ021, ,
NOMESCO Finland
161.8
15.5
16
*
L40.9
ICD-10 Finland
Psoriasis, unspecified
4.9
15.5
34
71
D05AX02
ATC
calcipotriol; topical
3.2
15.4
63
206
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
15.3
322
2064
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
2.1
15.1
157
801
R02
ICPC
Shortness of breath/dyspnoea
1.9
15.1
197
1090
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
15.1
337
2195
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
15.0
166
866
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
14.8
174
929
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.3
14.6
38
91
D11AH02
ATC
pimecrolimus; topical
+∞
14.6
14
*
J02AC01
ATC
fluconazole; systemic
1.6
14.5
506
3679
P01AB01
ATC
metronidazole; oral, rectal
1.6
14.5
533
3925
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
14.4
369
2489
R50.9
ICD-10 Finland
Fever, unspecified
1.9
14.3
208
1191
A02BC02
ATC
pantoprazole; systemic
1.6
14.3
931
7793
S06
ICPC
Rash localized
2.6
14.3
83
329
S18
ICPC
Laceration/cut
1.6
14.2
639
4922
B35.3
ICD-10 Finland
Tinea pedis
2.7
14.1
74
279
R60.0
ICD-10 Finland
Localized oedema
2.0
14.0
176
961
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
13.9
326
2144
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
13.9
972
8243
H02AB07
ATC
prednisone; oral
1.9
13.9
182
1007
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
3.8
13.9
42
113
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.0
13.8
39
100
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.1
13.7
58
194
K13.29
ICD-10 Finland
Indefinite leukoplakia
5.2
13.7
28
55
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
13.6
343
2300
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
13.4
383
2646
SPAT1260
SPAT
Consultation of another employee
1.8
13.4
229
1378
E66.8
ICD-10 Finland
Other obesity
2.4
13.2
89
379
R06AX13
ATC
loratadine; oral
1.9
13.2
194
1114
ZY010
NOMESCO Finland
Hospital outpatient
2.6
13.2
77
306
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
13.2
591
4522
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
13.2
889
7430
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.0
13.1
28
57
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
13.1
376
2598
WZC00, ,
SPAT
1.8
12.9
210
1244
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
22.8
12.9
18
8
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.3
12.8
102
468
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
12.8
527
3953
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
12.8
497
3681
J01MA02
ATC
ciprofloxacin; systemic
1.5
12.5
502
3738
L23.1
ICD-10 Finland
Allergic contact dermatitis due to adhesives
131.2
12.5
13
*
S01
ICPC
Pain/tenderness of skin
2.6
12.4
73
292
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
12.4
102
475
J01DA09
ATC
[U] cefadroxil
1.6
12.3
346
2373
A10AB05
ATC
insulin aspart; parenteral
2.2
12.0
110
534
A02BC03
ATC
lansoprazole; oral
1.6
12.0
378
2662
L17
ICPC
Foot/toe symptom/complaint
1.6
12.0
404
2890
SPAT1301
SPAT
No procedures
1.6
12.0
389
2759
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
11.9
333
2280
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
11.8
193
1143
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
11.8
169
961
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.7
11.8
63
240
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
4.5
11.7
28
63
SPAT1153
SPAT
Removal of sutures
1.6
11.7
406
2921
R03BA05
ATC
fluticasone; inhalant
1.7
11.7
234
1470
L13.0
ICD-10 Finland
Dermatitis herpetiformis
16.6
11.7
18
11
N06AX21
ATC
duloxetine; oral
1.9
11.6
170
973
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
11.6
260
1682
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
11.6
181
1058
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
+∞
11.5
11
*
J01AA02
ATC
doxycycline; systemic
1.6
11.5
1038
9094
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
11.4
512
3889
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
5.4
11.4
22
41
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.8
11.3
174
1011
QXA70, ,
SPAT
4.5
11.2
27
61
K02.1
ICD-10 Finland
Caries of dentine
1.5
11.2
779
6447
SPAT1262
SPAT
Handing over of treatment supplies
1.7
11.1
227
1434
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
11.0
489
3697
N02BE01
ATC
paracetamol; systemic, rectal
1.8
10.9
1217
11127
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.7
10.9
60
232
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.6
10.8
61
239
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
10.8
238
1532
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.6
10.8
35
99
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.8
10.8
179
1065
B01AB05
ATC
enoxaparin; parenteral
1.5
10.8
407
2973
E66.0
ICD-10 Finland
Obesity due to excess calories
5.0
10.8
23
47
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.0
10.7
113
580
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.5
10.6
36
105
G47.3
ICD-10 Finland
Sleep apnoea
1.6
10.5
322
2244
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
10.5
381
2758
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.1
10.4
98
481
WZA90
NOMESCO Finland
Other medical or dental certificate
1.6
10.4
305
2106
PHD99
NOMESCO Finland
Resection of other vein
2.2
10.3
89
423
T90
ICPC
Diabetes non-insulin dependent
1.6
10.1
322
2260
PHD76
NOMESCO Finland
Resection of long saphenous vein
2.4
10.1
70
302
L85.3
ICD-10 Finland
Xerosis cutis
5.3
10.1
20
38
SPAT1254
SPAT
Administration of medicine
1.7
10.1
181
1100
R60.9
ICD-10 Finland
Oedema, unspecified
2.3
10.1
79
360
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
10.1
78
354
Z94.0
ICD-10 Finland
Kidney transplant status
5.1
10.1
21
42
395
Kela drug reimbursment
Dupilumab
40.4
10.0
12
*
Z01.2
ICD-10 Finland
Dental examination
1.4
10.0
601
4800
S08
ICPC
Skin colour change
2.2
9.9
79
363
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.3
9.9
37
115
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.0
9.9
112
589
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
9.9
171
1029
J01CF05
ATC
flucloxacillin; systemic
2.1
9.9
100
505
D06AX01
ATC
fusidic acid; topical
1.9
9.9
121
654
S91
ICPC
Psoriasis
5.2
9.8
20
39
R03DC03
ATC
montelukast; oral
1.7
9.8
209
1332
L40
ICD-10 Finland
Psoriasis
3.2
9.8
38
121
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
9.8
137
774
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
9.7
319
2253
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
9.7
226
1472
S19
ICPC
Skin injury other
2.5
9.6
59
241
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.4
9.6
67
291
L21.0
ICD-10 Finland
Seborrhoea capitis
10.1
9.5
18
18
R06AX22
ATC
ebastine; oral
1.7
9.5
210
1351
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
2.9
9.4
44
156
127
Kela drug reimbursment
Transplant complication
3.9
9.4
27
70
D11AH05
ATC
dupilumab; topical
30.2
9.4
12
*
EB1VA, ,
NOMESCO Finland
1.6
9.4
242
1616
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
9.4
238
1583
D07AC03
ATC
desoximetasone; topical
3.8
9.4
28
75
SFA30
NOMESCO Finland
Three-surface restoration
1.4
9.3
568
4528
M03BX02
ATC
tizanidine; oral
1.4
9.3
817
6950
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
2.7
9.2
50
192
EBA00
NOMESCO Finland
Extraction of tooth
1.4
9.2
473
3650
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
9.2
287
2003
A10AE04
ATC
insulin glargine; parenteral
1.8
9.2
131
744
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
9.1
62
266
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
5.1
9.1
19
38
ZX120, ,
SPAT
3.8
9.1
27
72
N03AX16
ATC
[U] pregabalin
1.5
9.1
290
2034
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
9.1
153
914
L29.0
ICD-10 Finland
Pruritus ani
9.1
9.0
18
20
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
9.0
100
522
F41.09
ICD-10 Finland
UNS Panic Syndrome
3.0
9.0
39
133
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.5
9.0
388
2896
SFA10
NOMESCO Finland
One-surface restoration
1.4
9.0
714
5955
AA1AD
NOMESCO Finland
CT of head and brain
1.5
8.9
373
2764
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
8.9
100
524
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
8.9
942
8255
L50.9
ICD-10 Finland
Urticaria, unspecified
2.6
8.9
49
190
B86
ICD-10 Finland
Scabies
3.1
8.9
37
123
R03BA01
ATC
beclometasone; inhalant
1.7
8.9
173
1075
N06AB04
ATC
citalopram; systemic
1.6
8.9
255
1745
A11CC03
ATC
alfacalcidol; systemic
3.1
8.9
36
118
A10AD01
ATC
insulin (human); parenteral
3.6
8.9
28
78
R52.9
ICD-10 Finland
Pain, unspecified
1.8
8.8
135
784
A10AC01
ATC
insulin (human); parenteral
2.0
8.8
98
513
A10AE05
ATC
insulin detemir; parenteral
2.2
8.7
74
349
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.5
8.7
299
2128
C07AB07
ATC
bisoprolol; oral
1.4
8.7
609
4959
0350X
ICD-9 Finland
Erysipelas[ERYSIPELAS ALIA DEFINITA SEU NUD]
7.7
8.7
19
25
J46
ICD-10 Finland
Status asthmaticus
2.9
8.6
39
136
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.1
8.6
36
120
TK800
NOMESCO Finland
Hemodialysis
3.2
8.5
33
105
R11
ICD-10 Finland
Nausea and vomiting
1.9
8.5
114
634
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.1
8.5
85
428
A03
ICPC
Fever
1.6
8.4
209
1381
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.6
8.4
193
1252
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
8.3
159
982
L26
ICD-10 Finland
Exfoliative dermatitis
+∞
8.3
8
*
6929X
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[DERMATITITIS ARTEFACTA NUD]
+∞
8.3
8
*
D07AB01
ATC
clobetasone; topical
2.7
8.3
42
156
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
8.3
144
867
SPAT1310
SPAT
Counselling related to known health issue
1.5
8.3
378
2845
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
8.3
140
837
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
8.2
595
4858
C03DA01
ATC
spironolactone; oral
1.7
8.2
150
917
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
8.1
144
873
L23.5
ICD-10 Finland
Allergic contact dermatitis due to other chemical products
33.5
8.1
10
*
K59.09
ICD-10 Finland
Constipation, unspecified
2.0
8.1
89
464
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
8.1
127
743
K07
ICPC
Swollen ankles/oedema
2.2
8.0
65
301
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
8.0
229
1562
L24.9
ICD-10 Finland
Irritant contact dermatitis, unspecified cause
22.2
8.0
11
5
SPAT1097
SPAT
Recording of ECG
1.6
8.0
181
1169
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.8
8.0
117
670
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
8.0
110
618
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
3.4
8.0
28
84
SPAT1151
SPAT
Treatment of major wounds
4.3
7.9
20
47
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.8
7.9
125
732
J01MA12
ATC
levofloxacin; systemic
1.6
7.9
228
1560
SPAT1255
SPAT
Intravenous administration of medicine
2.0
7.9
85
440
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
6.1
7.9
20
33
L04AX01
ATC
azathioprine; systemic
2.4
7.8
54
234
A10AB04
ATC
insulin lispro; parenteral
2.6
7.8
45
179
SFA20
NOMESCO Finland
Two-surface restoration
1.4
7.8
757
6464
EKA10
NOMESCO Finland
iopsy of buccal mucosa
2.9
7.8
35
122
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.8
7.7
118
684
M54.5
ICD-10 Finland
Low back pain
1.4
7.7
467
3687
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.3
7.7
56
248
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.6
7.7
167
1067
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.3
7.7
58
261
A10BA02
ATC
metformin; oral
1.4
7.7
357
2691
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.0
7.6
81
417
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.8
7.6
118
687
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
7.6
703
5945
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
7.6
218
1488
N18.8
ICD-10 Finland
Other chronic renal failure
3.1
7.6
31
102
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
7.6
867
7585
L98.1
ICD-10 Finland
Factitial dermatitis
25.2
7.6
10
*
H01
ICPC
Ear pain/earache
1.7
7.5
138
843
J04BA02
ATC
dapsone; oral
10.1
7.5
14
14
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
7.5
179
1171
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.4
7.5
48
201
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
7.4
448
3530
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
2.3
7.4
53
233
N06AA09
ATC
amitriptyline; systemic
1.8
7.4
117
685
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
80.5
7.4
8
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.0
7.4
73
366
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
7.4
657
5513
R03BB04
ATC
tiotropium bromide; inhalant
1.7
7.4
126
755
WVA20, ,
SPAT
2.3
7.4
56
253
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
7.3
89
480
D07XB01
ATC
flumetasone; topical
8.4
7.3
15
18
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.8
7.3
36
132
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
6.9
7.3
17
25
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
7.3
124
742
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
+∞
7.3
7
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
7.3
359
2730
A02BC05
ATC
esomeprazole; systemic
1.4
7.3
507
4091
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
15.8
7.2
11
7
L30.1
ICD-10 Finland
Dyshidrosis [pompholyx]
15.8
7.2
11
7
L73.8
ICD-10 Finland
Other specified follicular disorders
5.8
7.2
19
33
KMAK, ,
NOMESCO Finland
1.4
7.2
639
5352
H57.1
ICD-10 Finland
Ocular pain
2.3
7.2
52
230
J02AC02
ATC
itraconazole; systemic
1.5
7.2
209
1431
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
2.2
7.2
56
256
L04AA01
ATC
[U] ciclosporin
4.0
7.2
20
51
J01EA01
ATC
trimethoprim; systemic
1.5
7.2
294
2161
SPAT1312
SPAT
General health counselling
1.4
7.2
365
2792
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
7.1
99
558
L03
ICPC
Low back symptom/complaint
1.4
7.1
365
2794
A41.9
ICD-10 Finland
Sepsis, unspecified
2.4
7.1
47
200
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
7.1
362
2769
M25.5
ICD-10 Finland
Pain in joint
1.4
7.1
419
3288
E66.00
ICD-10 Finland
Metabolic syndrome
2.0
7.0
80
422
L15
ICPC
Knee symptom/complaint
1.4
7.0
324
2432
UKC02
NOMESCO Finland
Cystoscopy
1.6
7.0
185
1239
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.8
7.0
98
554
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.6
7.0
40
159
L29
ICD-10 Finland
Pruritus
4.4
7.0
17
39
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
7.0
118
706
SPAT1193
SPAT
Pap smear
1.8
7.0
98
555
SFA00
NOMESCO Finland
Small restoration
1.6
6.9
174
1151
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.4
6.9
47
202
T78.4
ICD-10 Finland
Allergy, unspecified
2.3
6.9
50
221
WVA30, ,
SPAT
1.9
6.9
88
482
N03AX12
ATC
[U] gabapentin; oral
1.5
6.9
198
1350
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
6.9
106
616
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
6.9
44
184
P29
ICPC
Psychological sympt/compl other
1.9
6.9
90
498
L71.8
ICD-10 Finland
Other rosacea
3.4
6.8
24
72
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.5
6.8
270
1968
N06AA12
ATC
doxepin; systemic
2.1
6.8
65
322
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
6.8
318
2392
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
6.8
296
2198
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.4
6.8
46
198
L04AA06
ATC
mycophenolic acid; systemic
3.1
6.8
27
88
E53.9
ICD-10 Finland
Vitamin B deficiency, unspecified
16.8
6.7
10
6
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
2.1
6.7
62
303
S88
ICPC
Dermatitis contact/allergic
3.2
6.7
26
83
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.5
6.7
22
63
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
6.7
116
698
N30.0
ICD-10 Finland
Acute cystitis
1.5
6.7
196
1343
A07AA02
ATC
nystatin; oral
2.0
6.7
68
345
WZC30
NOMESCO Finland
Teaching
1.5
6.7
209
1454
J01FA06
ATC
roxithromycin; oral
1.4
6.6
485
3930
L40.8
ICD-10 Finland
Other psoriasis
5.9
6.6
17
29
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.9
6.6
29
100
A02BC01
ATC
omeprazole; systemic
1.4
6.6
323
2448
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
6.6
268
1964
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.5
6.6
38
152
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.9
6.5
30
106
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
1.6
6.5
135
852
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.4
6.5
44
189
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
6.5
284
2107
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.3
6.5
47
208
D06
ICPC
Abdominal pain localized other
1.8
6.5
104
612
K90.0
ICD-10 Finland
Coeliac disease
2.6
6.5
37
147
A10AB01
ATC
insulin (human); parenteral
2.4
6.5
44
190
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
4.0
6.4
18
46
-, ,
ICD-10 Finland
2.8
6.4
30
107
E66.9
ICD-10 Finland
Obesity, unspecified
2.3
6.4
49
222
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
3.2
6.4
24
75
L24.0
ICD-10 Finland
Irritant contact dermatitis due to detergents
70.2
6.4
7
*
XCK00
NOMESCO Finland
Perimetry
2.0
6.4
70
365
A29
ICPC
General symptom/complaint other
1.6
6.4
165
1099
SPAT1284
SPAT
Extensive health certificate
2.6
6.4
36
142
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
6.4
540
4466
H04.10
ICD-10 Finland
Dry eye syndrome
1.6
6.4
139
889
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.1
6.4
26
86
A10BJ02
ATC
liraglutide; parenteral
2.4
6.3
41
173
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
2.6
6.3
34
131
I50.0
ICD-10 Finland
Congestive heart failure
1.9
6.3
83
460
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
5.2
6.3
18
35
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
6.3
105
626
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.7
6.3
105
626
B07.9
ICD-10 Finland
Verruca simplex
2.3
6.3
45
199
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.9
6.3
81
447
6983A
ICD-9 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus[PRURIGO NODULARIS HYDE]
+∞
6.3
6
*
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
+∞
6.3
6
*
69798
ICD-8 Finland
Lichen, Alius definitus
+∞
6.3
6
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
6.2
158
1048
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.8
6.2
86
485
M79.1
ICD-10 Finland
Myalgia
1.5
6.2
184
1264
J01CA04
ATC
amoxicillin; systemic
1.4
6.2
1055
9658
L14
ICPC
Leg/thigh symptom/complaint
1.7
6.2
103
614
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
6.2
775
6776
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
2.6
6.2
33
127
B03BA03
ATC
hydroxocobalamin; parenteral
2.0
6.2
63
321
5613
FHL
Conjunctival occlusion
7.7
6.1
13
17
OAB50, ,
SPAT
1.7
6.1
107
646
N05CF01
ATC
zopiclone; oral
1.4
6.1
375
2948
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.6
6.1
158
1053
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
6.1
87
495
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.8
6.1
81
451
N47
ICD-10 Finland
Redundant prepuce, phimosis and paraphimosis
2.3
6.1
43
189
J45.8
ICD-10 Finland
Mixed asthma
2.4
6.1
38
158
L16
ICPC
Ankle symptom/complaint
1.6
6.1
145
949
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.8
6.0
85
482
SPAT1252
SPAT
Overall medication plan or its review
1.8
6.0
82
460
A01AB09
ATC
miconazole; local oral
1.7
6.0
101
603
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.4
6.0
40
171
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.2
6.0
17
33
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.3
6.0
43
190

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
231
399
6.75
132.04
1.3
1.2
—
—
—
0
0
190
703
2.97
37.89
1.5
1.3
424.39
159.81
u/ml
1.75
176
648
298
1408
2.42
36.38
1.7
1.4
—
—
—
0
0
860
6175
2.04
34.79
8.0
6.2
0.05
0.04
e9/l
4.48
797
5285
858
6169
2.03
34.40
8.0
6.2
0.60
0.58
e9/l
1.36
793
5284
876
6377
2.02
33.51
8.2
6.4
0.23
0.19
e9/l
8.39
816
5561
864
6295
1.99
32.52
8.2
6.3
1.83
1.93
e9/l
1.27
805
5535
276
1330
2.34
31.85
2.3
1.6
—
—
—
0
0
312
1681
2.11
26.90
1.5
1.3
541.87
473.01
titre
0.22
75
355
579
3898
1.83
25.58
3.6
2.6
59.79
80.63
u/l
0.50
550
3620
896
6915
1.84
24.87
11.4
9.7
4.29
4.09
e9/l
1.91
826
6029
509
3339
1.83
24.12
5.4
4.3
—
—
—
0
0
767
5692
1.78
23.83
8.4
6.6
8.57
8.85
%
2.21
745
5338
769
5713
1.78
23.79
8.0
6.3
58.13
57.35
%
1.15
755
5466
765
5689
1.77
23.44
8.5
6.5
0.71
0.68
%
0.58
743
5325
764
5684
1.77
23.33
8.4
6.4
3.28
2.82
%
5.22
742
5328
774
5834
1.74
22.07
8.5
6.4
26.66
27.74
%
2.16
756
5532
301
1741
1.93
20.69
2.5
2.0
—
—
—
0
0
551
3834
1.73
20.49
2.5
2.2
175.43
214.14
u/l
0.52
523
3650
380
2382
1.82
20.24
1.7
1.5
2.79
2.49
g/l
1.42
245
1495
574
4079
1.70
19.49
7.7
6.2
—
—
—
0
0
458
3066
1.74
19.31
2.7
2.2
2.78
2.84
mg/l
0.21
417
2636
566
4017
1.69
19.24
3.9
3.5
81.72
45.83
mg/l
1.31
381
2549
1101
9352
1.87
19.17
10.1
8.2
81.14
79.11
u/l
0.70
1065
8880
415
2719
1.75
18.79
1.5
1.3
2.49
1.55
u/ml
0.61
115
755
572
4098
1.67
18.58
4.6
4.1
12.65
8.02
mg/mmol
0.88
385
2538
363
2295
1.79
18.55
1.4
1.3
32.88
31.96
iu/ml
0.05
124
714
710
5406
1.64
17.97
6.4
5.1
35.38
35.75
g/l
1.02
677
5092
890
7193
1.66
17.63
7.0
5.0
6.95
6.69
mmol/l
2.62
848
6849
509
3578
1.67
17.53
3.5
3.1
—
—
—
0
0
326
2029
1.79
17.42
3.6
2.6
12.42
13.19
umol/l
1.22
307
1893
202
1080
2.02
17.19
10.2
7.3
10.58
9.69
mmol/l
0.92
194
1042
335
2125
1.76
16.69
1.4
1.3
12.88
12.29
u/ml
0.05
128
836
580
4269
1.62
16.32
3.8
3.4
7.39
7.67
mmol/l
0.92
505
3613
810
6477
1.60
15.98
6.7
6.7
11.53
11.67
umol/l
0.06
787
6191
665
5088
1.59
15.72
4.0
3.3
6.30
6.21
ph
1.39
401
2918
795
6344
1.59
15.69
4.9
3.7
0.00
0.00
estimate
0.50
174
1346
303
1897
1.76
15.69
3.6
2.5
2.31
2.32
g/l
0.05
285
1757
802
6429
1.59
15.39
4.9
3.7
7.42
3.61
estimate
0.21
175
1377
804
6463
1.58
15.13
4.9
3.7
6.25
0.24
estimate
0.48
162
1284
638
4868
1.58
15.03
4.7
3.6
0.07
0.03
estimate
0.78
143
1116
411
2824
1.65
14.98
4.8
3.8
1.02
1.02
kg/l
0.22
299
1909
404
2764
1.65
14.98
6.1
4.6
—
—
—
0
0
770
6146
1.57
14.80
10.7
7.2
1.21
1.21
mmol/l
0.27
679
5294
204
1160
1.89
14.37
2.8
2.1
366.46
379.87
nmol/l
0.39
196
1081
227
1338
1.83
14.27
1.8
1.6
—
—
—
0
0
712
5636
1.54
13.82
16.7
13.9
1.23
1.23
inr
0.05
621
4709
266
1664
1.74
13.63
9.3
5.6
1.09
1.03
mmol/l
2.40
255
1543
276
1745
1.73
13.61
3.7
2.6
21.37
23.28
%
1.74
259
1630
102
457
2.33
13.52
1.7
1.8
8.15
8.34
iu/ml
0.02
25
107
699
5531
1.53
13.45
2.9
2.4
73.20
77.60
nmol/l
4.36
650
5005
920
7749
1.56
13.14
6.0
4.4
38.72
1828.38
e6/l
2.14
18
117
79
320
2.56
13.04
2.0
2.3
11.83
11.69
mg/l
0.05
74
300
243
1507
1.74
12.78
2.6
2.4
130.02
122.59
ug/g
0.17
206
1211
209
1243
1.80
12.68
5.7
3.5
7.37
7.38
ph
0.84
130
707
162
894
1.92
12.44
2.9
3.0
146.65
195.78
ng/l
0.95
148
822
690
5502
1.51
12.43
9.4
6.5
1.21
1.21
mmol/l
0.61
653
5083
490
3640
1.54
12.32
3.3
3.1
1748.71
1237.17
ng/l
1.14
430
3099
383
2693
1.58
12.29
3.7
2.6
4.77
5.56
e6/l
0.56
360
2450
956
8174
1.55
12.29
5.9
4.4
—
3.63
—
0
16
53
180
3.02
12.20
1.0
1.1
6.01
4.17
u/ml
0.19
24
92
672
5343
1.50
12.19
2.4
2.1
94.16
96.72
pmol/l
0.74
391
2839
699
5611
1.50
12.05
4.1
3.0
115.79
133.63
ug/l
1.95
657
5246
246
1561
1.70
11.84
3.3
3.3
5.55
4.43
e9/l
0.63
223
1366
216
1339
1.73
11.29
2.6
2.8
1.68
1.82
%
1.65
199
1209
174
1013
1.82
11.27
2.9
3.1
66.68
66.55
g/l
0.09
163
936
259
1694
1.65
11.06
1.7
1.6
—
—
—
0
0
599
4716
1.48
11.04
4.0
3.7
40.06
59.70
ng/l
0.67
418
3351
1055
9316
1.56
10.85
5.2
4.3
14.79
14.77
pmol/l
0.10
1008
8587
96
461
2.16
10.79
1.3
1.2
3.72
1.04
u/ml
—
6
34
196
1197
1.74
10.78
5.9
3.5
1.24
1.94
mmol/l
1.90
175
1019
225
1432
1.68
10.64
9.1
8.1
7.41
7.41
ph
0.14
140
802
50
178
2.88
10.62
1.1
1.1
0.52
1.64
u/ml
0.83
20
71
432
3207
1.50
10.55
3.1
2.7
349.82
341.99
umol/l
0.87
390
2849
470
3553
1.49
10.49
5.3
3.8
0.00
0.01
estimate
1.34
157
1259
1270
11792
1.93
10.46
23.6
15.3
23.91
24.05
mg/l
0.05
1130
9689
145
820
1.86
10.29
2.5
2.8
—
—
—
0
0
459
3469
1.48
10.19
1.9
1.7
20.10
20.38
nmol/l
0.14
396
2934
285
1945
1.59
10.15
2.0
1.8
—
—
—
0
0
174
1045
1.76
10.13
2.5
2.8
66.26
71.12
e9/l
1.46
141
764
222
1426
1.66
10.11
8.9
8.1
0.97
0.95
mmol/l
0.03
171
1175
223
1437
1.66
10.02
8.8
8.1
5.02
5.12
kpa
1.08
213
1386
223
1438
1.66
10.00
8.9
8.1
11.74
12.24
kpa
0.63
213
1386
109
568
2.00
9.87
4.8
4.9
1.70
1.57
%
0.63
101
536
161
953
1.78
9.84
5.2
3.7
100.91
84.36
ng/l
1.19
142
839
302
2111
1.55
9.64
3.2
3.4
0.80
0.82
mmol/l
1.74
281
2002
86
417
2.13
9.45
1.5
1.2
—
—
—
0
0
100
516
2.01
9.31
1.7
1.9
1.95
1.96
ug/l
0.00
87
457
534
4210
1.44
9.31
3.6
3.3
31.19
33.25
u/l
0.81
509
3976
136
779
1.83
9.26
8.8
6.6
24.30
24.51
mmol/l
0.24
128
743
53
210
2.58
9.21
1.2
1.1
4.26
1.65
u/ml
0.34
27
114
202
1298
1.65
9.14
9.4
8.4
95.64
95.42
%
0.27
194
1256
22
50
4.45
9.10
1.0
1.0
0.40
1.72
u/ml
—
9
16
282
1969
1.54
8.99
1.8
1.7
1178.90
1208.00
nmol/l
0.21
238
1493
158
958
1.73
8.87
3.2
2.8
11.31
10.71
g/l
0.81
145
891
99
523
1.96
8.64
5.0
5.1
0.84
0.88
%
0.39
92
492
469
3655
1.43
8.54
6.2
4.2
7.39
7.40
ph
0.81
369
2656
152
922
1.73
8.52
1.3
1.2
—
—
—
0
0
1195
11036
1.61
8.33
6.4
5.3
1.88
1.91
mu/l
0.36
1140
10241
530
4253
1.40
8.05
3.4
3.5
2.34
2.35
mmol/l
1.36
492
3885
125
729
1.79
8.03
5.6
4.8
—
—
—
0
0
112
633
1.84
7.97
1.3
1.2
—
—
—
0
0
33
110
3.05
7.92
1.5
1.3
30350.36
145224.81
e6/l
1.01
25
73
185
1208
1.61
7.81
10.1
8.7
120.08
122.44
g/l
0.80
178
1179
174
1129
1.62
7.54
5.1
4.5
0.60
1.08
%
2.33
67
342
679
5721
1.37
7.47
3.3
2.8
—
—
estimate
—
0
0
1282
12117
1.79
7.43
26.7
18.1
139.53
139.73
mmol/l
2.21
1262
11881
1284
12145
1.79
7.37
26.8
18.2
4.00
3.97
mmol/l
2.77
1263
11886
446
3528
1.39
7.19
4.1
3.2
0.01
0.04
estimate
0.65
137
1064
490
3943
1.38
7.10
4.4
3.2
46.06
77.74
e6/l
0.77
420
2985
360
2759
1.41
6.95
1.8
1.7
1.24
1.19
mg/l
0.13
293
2142
336
2544
1.42
6.95
1.7
1.7
419.00
33491220.96
pmol/l
2.44
290
2117
19
48
4.00
6.90
1.1
1.0
0.32
0.48
u/ml
—
5
10
64
314
2.09
6.89
1.9
1.6
11813.80
12809.00
e6/l
0.10
50
225
369
2846
1.40
6.85
4.5
3.5
0.33
0.17
—
6
29
309
2311
1.43
6.82
3.7
2.9
519.49
536.62
mosm/kgh2o
0.71
285
2021
163
1072
1.59
6.67
5.0
4.3
0.59
0.78
%
0.72
63
325
117
707
1.72
6.66
11.0
10.5
15.87
16.05
%
0.26
110
679
30
105
2.90
6.66
1.3
1.3
8.34
7.02
g/l
0.69
25
79
163
1076
1.58
6.56
5.3
4.6
0.09
0.11
%
0.15
56
290
70
362
1.98
6.54
1.2
1.2
688.00
1040.83
titre
—
5
12
122
751
1.68
6.49
2.1
1.8
1.16
1.39
g/l
0.75
112
699
1225
11509
1.56
6.46
6.1
5.1
6.18
5.95
mmol/l
4.51
1148
10610
14
19
7.43
6.41
1.1
1.0
0.65
0.10
u/ml
—
6
9
52
242
2.19
6.41
1.7
1.4
—
—
—
0
0
1206
11301
1.52
6.34
8.0
6.3
40.88
39.33
mmol/mol
6.45
1147
10611
63
319
2.02
6.26
1.4
1.2
1.84
2.47
u/ml
—
5
31
69
361
1.96
6.25
1.6
1.4
314.38
276.35
ug/g
0.70
42
208
40
170
2.39
6.09
1.1
1.1
1.64
0.69
u/ml
0.46
21
77
29
105
2.80
6.07
1.3
1.3
0.44
0.41
g/l
0.21
24
79
29
105
2.80
6.07
1.3
1.3
3.36
3.00
g/l
0.51
24
79
452
3665
1.35
6.02
6.8
6.3
—
—
—
0
0
33
129
2.60
5.98
1.5
1.2
—
—
—
0
0
58
292
2.03
5.87
1.2
1.1
11.04
3.81
eliau/ml
—
7
38
162
1096
1.54
5.86
5.6
4.8
0.47
0.15
%
0.37
51
282
155
1043
1.55
5.74
5.3
2.8
4.28
4.49
kpa
0.78
155
1005
93
552
1.73
5.67
1.9
1.9
—
—
—
0
0
628
5374
1.31
5.63
14.4
11.4
0.00
0.00
e9/l
1.31
545
4415
36
152
2.40
5.58
1.1
1.1
3.24
1.75
u/ml
0.28
20
68
28
105
2.70
5.52
1.3
1.3
—
—
—
0
0
537
4511
1.31
5.47
5.1
3.8
113.95
105.20
e6/l
0.06
433
3148
67
364
1.88
5.47
6.7
6.1
1.42
1.37
mmol/l
0.18
57
319
73
408
1.83
5.45
2.6
2.9
10.49
10.30
g/l
0.16
67
370
19
57
3.37
5.45
1.9
3.1
1041.16
1182.19
u/ml
0.11
19
57
24
84
2.89
5.37
1.2
1.1
—
—
—
0
0
52
261
2.03
5.33
6.9
6.8
12.02
11.40
mmol/l
0.61
45
236
32
131
2.48
5.31
1.1
1.0
0.20
0.06
u/ml
0.41
12
39
31
125
2.51
5.31
2.1
1.6
59.05
59.27
%
0.01
21
78
52
262
2.02
5.28
6.9
6.8
104.42
105.43
mmol/l
0.75
45
237
47
229
2.09
5.22
1.7
1.4
186.18
162.35
au/ml
0.70
11
68
11
15
7.38
5.14
1.0
1.1
—
—
—
0
0
171
1203
1.48
5.14
2.4
2.2
0.21
0.21
g/l
0.00
161
1128
33
140
2.39
5.09
1.1
1.1
5.84
2.43
u/ml
0.43
14
52
65
359
1.85
5.06
1.2
1.2
97.78
100.28
titre
—
9
36
418
3425
1.32
5.01
3.2
2.9
0.00
0.03
0.49
13
74
302
2362
1.36
4.97
5.0
3.8
246.58
470.48
ng/l
0.94
221
1820
1240
11799
1.49
4.87
5.9
5.0
1.38
1.46
mmol/l
9.15
1172
10999
1245
11859
1.50
4.84
6.2
5.1
4.58
4.66
mmol/l
2.08
1177
11146
51
264
1.97
4.83
4.5
4.5
—
—
—
0
0
50
258
1.97
4.78
1.2
1.2
—
—
—
0
0
15
42
3.60
4.77
1.6
1.5
—
—
—
0
0
43
210
2.08
4.77
1.0
1.0
—
—
—
0
0
22
79
2.81
4.72
1.2
1.1
—
—
—
0
0
70
405
1.77
4.70
3.8
4.3
42.58
64.89
mg/l
0.36
59
348
70
406
1.76
4.67
3.9
4.3
50.48
59.45
mg/l
0.24
58
350
247
1892
1.37
4.62
2.1
2.1
29.41
29.51
s
0.11
242
1847
109
717
1.56
4.49
6.9
3.6
23.54
24.23
mmol/l
1.47
109
709
161
1152
1.45
4.44
5.1
4.1
7.36
7.36
ph
0.00
126
838
131
900
1.50
4.43
1.5
1.5
—
—
—
0
0
53
288
1.87
4.38
2.0
2.2
130.24
131.35
g/l
0.12
42
238
303
2413
1.33
4.37
2.6
2.9
2.45
2.45
mmol/l
0.02
278
2186
406
3367
1.29
4.35
4.1
3.1
0.42
0.48
e6/l
0.16
337
2440
910
8318
1.27
4.33
4.0
3.4
48.91
49.27
u/l
0.05
861
7863
187
1387
1.40
4.23
1.4
1.3
—
—
—
0
0
58
328
1.80
4.23
6.2
2.6
59.82
60.79
%
0.13
58
319
20
73
2.77
4.19
1.7
1.7
—
—
—
0
0
25
105
2.41
3.99
1.4
1.2
—
—
—
0
0
69
418
1.68
3.98
1.0
1.1
—
—
—
0
0
38
192
2.01
3.90
1.5
1.6
0.95
0.82
g/l
0.27
32
156
23
94
2.47
3.89
1.8
1.4
16.26
32.37
%
1.60
14
59
29
132
2.22
3.88
1.3
1.6
22.90
25.74
ng/l
0.28
29
132
23
95
2.45
3.81
2.4
2.2
9.74
5.91
umol/l
0.37
18
63
29
133
2.21
3.81
3.4
2.0
10.11
10.34
%
0.11
29
133
48
266
1.83
3.77
1.8
1.7
—
—
—
0
0
46
253
1.85
3.70
2.2
2.5
16.22
16.38
%
0.12
46
248
49
275
1.81
3.70
3.8
4.7
—
—
—
0
0
1303
12620
1.56
3.68
29.1
20.1
81.89
77.10
umol/l
2.89
1295
12491
1185
11288
1.35
3.68
5.1
4.3
1.44
1.30
mmol/l
7.41
1111
10431
60
359
1.70
3.65
3.3
4.1
1.39
3.51
ratio
1.33
35
207
33
163
2.05
3.62
1.3
1.5
—
—
—
0
0
33
163
2.05
3.62
1.3
1.5
—
—
—
0
0
33
163
2.05
3.62
1.3
1.5
—
—
—
0
0
33
163
2.05
3.62
1.3
1.5
—
—
—
0
0
13
35
3.74
3.59
1.7
1.2
39.25
37.98
g/l
—
8
19
82
535
1.57
3.55
1.8
1.9
1.80
1.52
g/l
1.96
68
479
118
832
1.46
3.55
1.2
1.2
111.20
140.84
u/ml
0.44
47
312
116
816
1.46
3.53
4.2
3.6
7.40
7.42
ph
1.57
98
690
119
842
1.45
3.51
4.3
3.6
5.19
5.17
kpa
0.06
113
817
15
53
2.85
3.36
1.5
1.4
175.63
173.48
mmol/24h
0.03
15
53
138
1013
1.40
3.34
2.4
2.3
4.75
7.84
ug/l
3.20
122
912
6
7
8.60
3.26
1.2
1.3
—
—
—
0
0
15
54
2.80
3.26
57.7
35.6
7.18
7.32
ug/l
0.09
15
47
180
1386
1.34
3.25
2.4
2.8
7.38
8.29
umol/l
0.30
160
1237
214
1692
1.31
3.21
1.4
1.2
—
—
—
0
0
16
61
2.64
3.14
1.1
1.0
—
—
—
0
0
69
447
1.57
3.11
4.3
3.7
160.40
307.82
mg/l
2.05
30
191
1247
12026
1.37
3.11
6.8
5.8
2.68
2.73
mmol/l
1.29
1179
11245
11
32
3.46
2.90
1.1
1.0
—
—
—
0
0
7
13
5.41
2.87
17.4
4.2
5.39
5.46
mmol/l
—
7
13
141
1067
1.36
2.86
13.2
9.1
—
—
—
0
0
24
116
2.09
2.83
3.4
4.4
—
—
—
0
0
27
137
1.99
2.81
1.2
1.1
—
—
—
0
0
9
236
0.38
2.81
1.4
1.7
—
—
—
0
0
103
742
1.42
2.81
2.9
3.6
4.41
4.53
pmol/l
0.63
92
662
113
830
1.39
2.76
2.4
2.5
12.34
19.03
au/ml
1.21
11
85
52
325
1.62
2.75
1.9
2.0
2.46
21.36
iu/l
0.56
25
134
122
910
1.37
2.72
1.8
1.7
—
—
—
0
0
28
146
1.94
2.71
1.6
1.4
272.67
279.98
mosm/kgh2o
0.82
21
115
38
219
1.76
2.70
5.2
3.4
4.25
4.09
e9/l
0.17
38
219
349
2986
1.23
2.70
2.9
2.4
—
—
—
0
0
12
40
3.02
2.69
7.7
4.9
—
—
—
0
0
36
205
1.78
2.67
1.1
1.1
—
—
—
0
0
81
566
1.46
2.61
1.4
1.4
29.09
30.19
iu/l
0.12
70
491
10
30
3.35
2.60
1.5
1.4
—
—
—
0
0
17
74
2.31
2.58
1.1
1.2
136.29
141.76
nmol/l
0.15
17
74
82
1144
0.70
2.57
1.2
1.4
—
—
—
0
0
578
5207
1.19
2.56
2.2
1.9
1.46
1.36
mmol/l
1.91
495
4387
84
594
1.44
2.55
2.6
2.2
0.00
1.39
estimate
0.50
27
181
44
270
1.65
2.52
4.1
3.6
—
—
—
0
0
1258
12209
1.33
2.47
20.8
13.8
—
—
—
0
0
37
218
1.72
2.46
1.5
1.3
55.23
62.84
mmol/l
0.76
30
182
8
21
3.83
2.46
1.1
1.4
—
—
—
0
0
1287
12537
1.38
2.43
16.2
11.9
26.51
26.66
u/l
0.14
1262
12223
5
8
6.27
2.37
1.4
1.1
—
—
—
0
0
39
236
1.67
2.37
4.2
4.1
2.42
2.50
mmol/l
0.07
26
164
48
307
1.58
2.35
1.4
1.4
14.84
9.54
u/l
1.18
42
240
49
315
1.58
2.35
1.5
1.2
—
—
—
0
0
147
1157
1.30
2.31
2.4
2.1
0.00
0.02
estimate
0.78
34
245
9
28
3.23
2.31
1.0
1.4
—
—
—
0
0
21
106
2.00
2.26
3.3
2.5
1006.52
1023.15
mg
0.01
21
106
101
758
1.36
2.21
1.3
1.3
70.56
46.52
au/ml
—
5
61
65
452
1.46
2.19
3.7
2.8
24.18
24.92
mmol/l
0.77
65
447
43
273
1.59
2.19
5.5
3.3
59.38
57.25
%
0.54
43
273
446
3973
1.18
2.18
2.8
2.5
—
—
—
0
0
24
129
1.88
2.17
1.5
2.4
—
—
—
0
0
246
2076
1.22
2.16
3.3
2.9
0.58
1.05
e6/l
5.37
150
1079
14
61
2.31
2.15
3.2
2.7
356.57
220.30
e6/l
0.43
14
54
61
421
1.47
2.14
1.8
1.6
23.35
11.98
u/ml
0.50
12
92
46
299
1.56
2.13
3.0
2.9
1.40
1.59
mmol/l
1.03
46
290
44
284
1.57
2.10
1.4
1.3
21.47
44.45
e6/l
0.40
34
214
29
168
1.74
2.08
1.7
2.6
—
—
—
0
0
49
325
1.53
2.08
3.3
2.9
8.08
8.12
kpa
0.07
49
318
37
230
1.63
2.06
5.9
3.1
11.78
8.45
pmol/l
0.95
37
230
44
286
1.56
2.05
1.5
1.4
6891.53
829.55
e6/l
0.53
36
224
38
239
1.61
2.03
1.7
1.2
289.23
250.90
u/ml
0.30
22
146
527
4790
1.16
1.97
2.2
2.1
—
—
—
0
0
7
21
3.34
1.96
2.0
1.9
—
—
—
0
0
102
783
1.33
1.95
10.8
8.6
24.28
24.88
mmol/l
1.11
102
778
38
243
1.58
1.91
3.1
3.1
7.12
7.71
mmol/l
0.84
38
235
163
1339
1.25
1.85
1.6
1.6
—
—
—
0
0
205
2413
0.82
1.82
2.8
3.2
0.67
0.76
ug/l
1.02
127
1525
25
145
1.74
1.82
1.0
1.2
—
—
—
0
0
22
123
1.80
1.80
1.3
1.2
—
—
—
0
0
31
486
0.63
1.80
1.0
1.2
1.51
1.55
g/l
0.35
31
486
13
60
2.18
1.78
1.1
1.1
1550.54
1469.60
miu/ml
0.09
13
60
40
264
1.53
1.77
1.3
1.2
30.42
60.79
u/ml
—
5
28
26
154
1.70
1.77
2.3
2.6
0.99
1.22
g/24h
0.34
21
93
30
185
1.64
1.76
5.5
5.8
336.20
358.93
umol/l
0.30
25
164
6
18
3.34
1.74
1.2
1.2
—
—
—
0
0
1033
9910
1.17
1.74
26.7
19.1
13.78
13.61
%
3.69
1023
9774
29
178
1.64
1.73
2.0
2.2
0.78
0.94
%
1.29
22
125
7
24
2.93
1.72
1.0
1.3
—
—
—
0
0
19
103
1.86
1.72
1.1
1.1
—
—
—
0
0
142
1162
1.25
1.68
2.8
2.3
35.73
41.06
u/l
0.44
124
978
52
367
1.43
1.68
1.4
1.2
—
—
—
0
0
10
40
2.51
1.66
1.0
1.4
7.88
9.69
mmol/l
—
10
40
124
1001
1.26
1.65
5.6
3.7
1.22
1.23
mmol/l
0.49
113
858
30
189
1.60
1.64
1.5
1.2
2.88
5.74
u/ml
0.92
17
80
52
370
1.42
1.62
1.2
1.3
196.90
218.44
miu/ml
0.13
14
169
42
287
1.48
1.61
2.6
2.3
51.96
101.58
ug/min
0.89
20
172
21
121
1.75
1.59
1.2
1.1
—
—
—
0
0
22
129
1.72
1.57
1.5
1.4
33395.47
85837.06
e6/l
0.46
15
68
75
572
1.33
1.55
5.0
3.7
—
—
—
0
0
34
502
0.67
1.53
1.0
1.2
0.94
0.91
g/l
0.28
34
502
111
1366
0.80
1.52
2.1
2.0
3.89
3.52
ratio
1.51
81
1077
37
250
1.49
1.51
3.1
3.3
24.45
24.92
mg/l
0.03
23
175
103
824
1.27
1.50
1.4
1.3
—
—
—
0
0
22
132
1.68
1.46
2.6
2.4
—
—
—
0
0
5
16
3.13
1.44
1.4
1.1
—
—
—
0
0
118
965
1.24
1.44
2.9
2.4
5.99
6.07
ph
0.36
79
642
14
252
0.55
1.43
1.6
1.2
—
—
—
0
0
25
157
1.60
1.41
1.2
1.1
3.26
2.18
eliau/ml
—
8
71
9
40
2.26
1.40
1.0
1.1
—
—
—
0
0
9
40
2.26
1.40
1.0
1.0
—
—
—
0
0
38
265
1.45
1.35
1.6
1.3
—
—
—
0
0
17
97
1.76
1.35
1.4
1.1
98.41
106.53
pmol/l
0.26
17
97
1311
12920
1.28
1.26
35.7
23.4
255.75
250.39
e9/l
2.04
1294
12685
48
355
1.36
1.25
2.0
1.6
310.88
302.20
mu/l
0.05
43
329
6
25
2.41
1.24
1.8
1.5
46.67
31.21
%
—
6
14
1311
12922
1.28
1.24
35.4
23.3
91.18
91.12
fl
0.18
1301
12802
11
56
1.97
1.22
1.5
1.3
28.00
29.47
umol/l
0.18
11
49
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
19
116
1.65
1.21
1.2
1.1
—
—
—
0
0
1311
12925
1.27
1.21
35.4
23.3
30.28
30.35
pg
0.74
1300
12804
1311
12925
1.27
1.21
36.3
23.8
40.28
40.51
%
0.84
1300
12795
1311
12925
1.27
1.21
35.5
23.3
4.48
4.51
e12/l
1.33
1293
12649
26
172
1.52
1.21
1.2
1.2
—
—
—
0
0
1311
12927
1.27
1.19
35.6
23.4
6.96
6.67
e9/l
5.82
1292
12648
15
86
1.75
1.19
2.3
2.6
7.73
8.31
mmol/l
0.25
15
86
1311
12930
1.26
1.16
35.8
23.5
134.44
135.88
g/l
2.82
1301
12807
45
334
1.36
1.16
4.0
2.9
1.78
2.17
index
0.20
23
174
7
30
2.34
1.12
11.3
6.2
5.94
5.21
kpa
—
7
30
8
40
2.01
1.12
1.9
1.5
—
—
—
0
0
7
138
0.50
1.10
1.1
1.1
—
—
—
0
0
12
66
1.83
1.09
2.0
3.0
2108.67
1965.43
ml
0.26
12
58
23
153
1.51
1.06
1.3
1.2
—
—
—
0
0
456
4884
0.90
1.06
3.6
3.2
—
—
—
0
0
57
447
1.29
1.03
5.2
3.8
24.20
24.95
mmol/l
0.96
50
415
9
46
1.96
1.03
1.2
1.4
1.94
1.85
umol/l
—
9
37
10
53
1.89
1.01
2.6
1.7
100.47
53.16
ug/l
—
10
53
16
99
1.62
1.00
1.3
1.3
7.94
0.71
u/ml
—
9
51
9
49
1.84
0.98
1.3
1.4
75.67
56.92
%
—
9
39
85
1016
0.83
0.95
1.9
1.8
3.53
3.51
mmol/l
0.05
57
717
25
175
1.44
0.93
1.2
1.2
—
—
—
0
0
21
142
1.49
0.92
1.5
1.4
5.30
6.52
mmol/l
1.51
21
134
46
358
1.29
0.91
11.7
10.1
—
—
—
0
0
29
211
1.38
0.88
1.2
1.1
99.80
2704.19
iu/ml
—
5
48
13
79
1.65
0.88
1.7
1.2
—
—
—
0
0
14
87
1.62
0.87
1.1
1.1
—
—
—
0
0
21
144
1.47
0.87
1.4
1.3
—
—
—
0
0
12
72
1.67
0.85
2.2
1.9
70.81
114.62
ng/l
2.02
12
72
214
1939
1.12
0.82
3.5
3.0
1.85
2.44
e6/l
0.70
115
945
21
290
0.72
0.75
1.3
1.3
—
—
—
0
0
51
623
0.81
0.74
1.8
1.7
—
—
—
0
0
5
24
2.09
0.74
1.4
2.6
22.24
19.28
umol/l
—
5
24
9
54
1.67
0.74
1.1
1.1
152.51
242.78
iu/ml
—
9
54
7
39
1.80
0.72
1.1
1.6
79.57
82.21
nmol/24h
—
7
39
14
92
1.53
0.72
1.0
1.4
—
—
—
0
0
16
109
1.47
0.71
4.4
2.7
13.22
12.25
index
—
9
67
24
177
1.36
0.71
2.2
1.5
0.19
0.35
nmol/l
1.60
13
133
5
26
1.93
0.70
4.2
2.6
18.60
6.00
ug/l
—
5
26
7
42
1.67
0.68
1.3
1.4
1.57
2.48
%
—
7
36
5
28
1.79
0.66
1.6
1.5
—
—
—
0
0
7
44
1.59
0.65
2.4
2.7
74.43
15.95
ug/l
—
7
37
10
154
0.65
0.64
1.2
1.6
—
—
—
0
0
23
172
1.34
0.64
1.2
1.2
—
—
—
0
0
18
129
1.40
0.63
1.7
1.4
—
—
—
0
0
27
209
1.30
0.60
2.1
1.7
—
—
—
0
0
0
23
0.00
0.58
0.0
6.5
—
7.35
—
0
23
0
23
0.00
0.58
0.0
3.3
—
46.70
—
0
23
10
149
0.67
0.56
1.2
1.5
—
—
—
0
0
6
36
1.67
0.56
1.5
1.4
2.78
3.46
mmol/l
—
6
30
10
148
0.67
0.55
1.1
1.5
1.02
1.31
mm
—
5
101
19
142
1.34
0.54
2.1
2.0
—
—
—
0
0
326
3088
1.07
0.51
5.0
4.0
91.35
90.10
%
0.41
317
3032
162
1491
1.10
0.51
4.8
5.0
30.62
31.86
%
0.84
123
1007
25
197
1.27
0.51
1.4
1.8
—
—
—
0
0
416
3975
1.07
0.51
5.1
5.3
2.18
2.64
ug/l
0.61
374
3600
11
75
1.47
0.50
1.0
1.0
—
—
—
0
0
6
41
1.47
0.50
1.5
2.8
0.55
0.61
mmol/l
—
6
41
67
588
1.15
0.48
2.7
2.3
—
—
—
0
0
21
164
1.28
0.46
3.0
2.8
—
—
—
0
0
17
221
0.77
0.46
3.1
4.0
20.55
30.50
u/ml
0.76
17
216
37
311
1.19
0.45
2.8
2.0
15584.29
5583.55
u/l
0.48
15
127
11
78
1.41
0.43
1.9
2.9
15.34
16.26
%
0.53
11
78
11
78
1.41
0.43
1.4
1.4
196.23
161.15
pmol/l
0.38
11
78
35
294
1.20
0.43
1.1
1.1
—
—
—
0
0
5
31
1.62
0.43
2.0
1.3
—
0.39
—
0
7
108
986
1.10
0.42
5.4
3.8
—
—
—
0
0
5
32
1.56
0.42
1.4
1.2
—
—
—
0
0
17
131
1.30
0.42
1.4
1.4
—
—
—
0
0
10
139
0.72
0.42
2.7
2.5
—
—
—
0
0
14
105
1.34
0.41
1.0
1.1
286.14
282.71
mg/l
0.08
14
92
0
17
0.00
0.40
0.0
1.0
—
69.65
—
0
17
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
13
97
1.34
0.39
1.8
1.9
1.29
1.86
u/field
—
7
51
5
35
1.43
0.39
1.2
1.1
16.57
16.73
umol/l
—
5
27
9
67
1.35
0.38
5.4
2.7
0.67
0.87
index
—
9
67
5
37
1.35
0.37
1.2
1.1
20.06
28.21
nmol/l
—
5
30
21
171
1.23
0.35
1.3
1.4
—
—
nmol/l
—
0
0
6
42
1.43
0.35
1.2
1.3
16.50
29.51
%
—
6
37
6
45
1.33
0.33
1.8
1.9
29.00
32.53
%
—
6
45
6
45
1.33
0.33
3.5
3.1
—
—
—
0
0
57
634
0.89
0.33
1.1
1.1
—
—
—
0
0
16
128
1.25
0.32
1.6
1.5
—
—
—
0
0
7
53
1.32
0.31
3.7
2.4
—
—
—
0
0
25
212
1.18
0.30
1.2
1.1
—
—
—
0
0
25
213
1.18
0.29
1.2
1.1
—
—
—
0
0
8
62
1.29
0.28
1.5
1.9
—
—
—
0
0
8
64
1.25
0.27
1.1
1.5
—
—
—
0
0
13
161
0.81
0.27
2.1
2.0
—
—
—
0
0
14
113
1.24
0.26
1.0
1.2
—
—
—
0
0
58
530
1.10
0.26
1.6
1.7
0.35
0.35
mg/l
0.02
26
255
5
38
1.32
0.23
1.0
1.0
—
—
—
0
0
5
38
1.32
0.23
1.0
1.0
—
—
—
0
0
5
38
1.32
0.23
1.0
1.0
—
—
—
0
0
5
39
1.28
0.23
1.0
1.1
—
—
—
0
0
5
40
1.25
0.22
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
188.20
—
0
10
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
25.17
—
0
6
0
12
0.00
0.21
0.0
1.1
—
36.17
—
0
6
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
6
48
1.25
0.20
1.2
2.2
41.17
40.43
g/l
—
6
48
6
49
1.23
0.20
3.5
2.9
—
—
—
0
0
113
1075
1.06
0.20
2.5
2.4
13.31
13.42
nmol/l
0.04
107
968
10
81
1.24
0.18
1.7
1.3
83.00
80.30
umol/l
—
10
81
20
175
1.14
0.18
1.8
2.5
—
—
—
0
0
18
157
1.15
0.17
1.9
1.7
14.16
21.38
ug/l
2.85
18
152
8
73
1.10
0.15
1.0
1.2
—
—
—
0
0
35
324
1.08
0.14
1.6
1.9
—
—
—
0
0
16
141
1.14
0.14
1.1
1.4
—
—
—
0
0
40
373
1.07
0.13
1.6
2.0
—
—
—
0
0
9
109
0.82
0.13
1.0
1.3
—
—
—
0
0
31
287
1.08
0.12
1.8
2.6
—
—
—
0
0
43
404
1.07
0.12
1.5
1.9
—
—
—
0
0
43
405
1.06
0.11
1.5
2.0
—
—
—
0
0
42
398
1.06
0.10
1.5
1.8
—
—
—
0
0
42
400
1.05
0.08
1.5
2.0
—
—
—
0
0
16
146
1.10
0.08
3.0
2.1
-0.60
0.57
mmol/l
0.52
16
141
7
64
1.09
0.08
1.0
1.1
—
—
—
0
0
127
1296
0.98
0.07
3.2
4.3
4.28
23.40
ug/l
2.12
110
1069
109
1066
1.02
0.07
1.5
1.4
—
—
—
0
0
351
3478
1.01
0.06
1.4
1.4
—
—
—
0
0
169
1665
1.02
0.06
1.3
1.3
—
—
—
0
0
14
130
1.08
0.04
3.1
2.5
—
—
—
0
0
120
1186
1.01
0.03
1.5
1.4
—
—
—
0
0
36
352
1.02
0.01
1.1
1.1
—
—
—
0
0
11
104
1.06
0.01
1.4
1.1
290.00
168.00
titre
—
5
15
13
126
1.03
0.00
2.2
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
0.14
—
0
6
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
5
58
0.86
-0.00
1.6
1.2
15.00
10.02
mm/h
—
5
58
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
5
56
0.89
-0.00
1.8
2.5
53.20
50.66
umol/l
—
5
49
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.9
0.88
7.00
nmol/l
—
6
53
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
418.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_LICHENSIMPLEX and mortality.

Females

Parameter HR [95% CI] p-value
L12_LICHENSIMPLEX 1.208 [1.06, 1.38] 0.004
Birth year 0.991 [0.98, 1.0] 0.044

During the follow-up period (1.1.1998 — 31.12.2019), 467 out of 3488 females with L12_LICHENSIMPLEX died.

Males

Parameter HR [95% CI] p-value
L12_LICHENSIMPLEX 1.41 [1.25, 1.59] < 0.001
Birth year 0.989 [0.98, 1.0] 0.022

During the follow-up period (1.1.1998 — 31.12.2019), 651 out of 3285 males with L12_LICHENSIMPLEX died.

Mortality risk

Mortality risk for people of age

years, who have L12_LICHENSIMPLEX.

N-year risk Females Males
1 0.065% 0.25%
5 0.621% 1.792%
10 1.481% 4.38%
15 2.961% 8.242%
20 5.346% 13.364%

Relationships between endpoints

Index endpoint: L12_LICHENSIMPLEX – Lichen simplex chronicus

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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