Cystic disease of liver

Q17_CYSTIC_DISEASE_OF_LIVER

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q44.6
  • Cause of death: ICD-10 Q44.6

2 out of 7 registries used, show all original rules.

273

4. Check minimum number of events

None

273

5. Include endpoints

None

273

6. Filter based on genotype QC (FinnGen only)

248

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 248 178 70
Unadjusted period prevalence (%) 0.05 0.06 0.03
Median age at first event (years) 57.23 55.23 62.30

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
255
Matched controls
2550
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q44.6
ICD-10 Finland
Cystic disease of liver
+∞
307.7
255
*
K76.80
ICD-10 Finland
Hepatic cyst
295.2
110.2
105
6
127
Kela drug reimbursment
Transplant complication
43.0
74.6
46
13
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
863.0
69.5
65
*
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
248.8
58.7
58
*
L04AA06
ATC
mycophenolic acid; systemic
26.3
58.2
42
19
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
25.4
53.5
39
18
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.5
51.3
98
196
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
18.3
41.7
35
22
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
7.0
40.1
74
140
JJ5KT
NOMESCO Finland
Sclerotherapy of liver cyst
+∞
36.3
34
*
JN3AD
NOMESCO Finland
Abdominal CT examination
5.8
35.8
85
203
JJA31
NOMESCO Finland
Laparoscopic marsupialisation of cyst of liver
+∞
35.2
33
*
A11CC03
ATC
alfacalcidol; systemic
15.1
34.6
32
24
Z94.0
ICD-10 Finland
Kidney transplant status
80.6
31.8
35
5
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.6
28.3
44
68
L04AD02
ATC
tacrolimus; systemic
60.6
27.9
32
6
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.4
27.1
64
149
Z94.4
ICD-10 Finland
Liver transplant status
78.1
25.4
28
*
TK800
NOMESCO Finland
Hemodialysis
23.1
25.2
36
18
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.7
23.7
149
700
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
72.0
23.3
26
*
JJC00
NOMESCO Finland
Allogenic transplantation of liver
92.1
23.1
25
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
39.1
22.6
28
8
Z49.1
ICD-10 Finland
Extracorporeal dialysis
39.4
20.2
25
7
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
30.6
19.1
25
9
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.3
19.0
119
540
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.7
18.2
37
74
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
102.3
17.8
19
*
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
192.8
17.7
18
*
JJ1AT
NOMESCO Finland
Puncture of lesion of liver with ultrasound guidance
192.8
17.7
18
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
5.5
17.7
37
76
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
14.0
17.7
30
24
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
34.2
17.3
22
7
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
68.1
17.0
19
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
181.4
16.7
17
*
H02AB04
ATC
methylprednisolone; systemic
3.5
15.4
65
228
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
15.1
162
954
B03XA02
ATC
darbepoetin alfa; parenteral
14.4
15.1
25
19
Z49.0
ICD-10 Finland
Preparatory care for dialysis
34.0
15.0
19
6
A12AA04
ATC
calcium carbonate; oral
18.4
14.6
22
13
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.6
14.1
55
182
V03AE02
ATC
sevelamer; oral
56.6
14.0
16
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.1
13.7
31
68
N18.8
ICD-10 Finland
Other chronic renal failure
13.3
12.9
22
18
7531A
ICD-9 Finland
Congenital anomalies of urinary system, Cystic kidney disease
+∞
12.6
12
*
L04AD01
ATC
ciclosporin; systemic
11.9
12.3
22
20
205
Kela drug reimbursment
Chronic hypertension
2.7
12.3
91
433
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
10.1
12.3
24
26
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.1
12.2
22
39
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.8
12.0
79
353
JJ5AT, ,
NOMESCO Finland
125.4
11.5
12
*
WX402
NOMESCO Finland
General anaesthesia
2.7
11.4
84
396
N18.0
ICD-10 Finland
End-stage renal disease
36.9
11.4
14
*
N02AX02
ATC
tramadol; systemic, rectal
2.5
11.3
140
843
UJF30
NOMESCO Finland
Ileoscopy through colon
3.4
11.1
46
157
C03CA01
ATC
furosemide; systemic
2.5
10.7
101
535
C08CA02
ATC
felodipine; oral
3.7
10.6
37
113
Q61.99
ICD-10 Finland
Cystic kidney disease, unspecified
+∞
10.5
10
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
15.4
10.1
16
11
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
41.8
10.1
12
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
7.9
9.9
22
30
V03AE01
ATC
polystyrene sulfonate; oral
21.1
9.9
14
7
J01MA02
ATC
ciprofloxacin; systemic
2.3
9.6
119
702
KAC00
NOMESCO Finland
Nephrectomy
103.7
9.5
10
*
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
22.7
9.4
13
6
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
22.7
9.4
13
6
Q61.1
ICD-10 Finland
Polycystic kidney, autosomal recessive
+∞
9.4
9
*
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
4.3
9.0
24
60
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
25.1
9.0
12
5
V03AE03
ATC
lanthanum carbonate; oral
28.6
8.6
11
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
8.3
8.5
18
23
7516D
ICD-9 Finland
Other congenital anomalies of digestive system, Anomalies of gallbladder, bile ducts and liver[HEPAR POLYCYSTICUM]
+∞
8.4
8
*
R50.9
ICD-10 Finland
Fever, unspecified
2.6
8.2
53
231
TPH07
NOMESCO Finland
Cathetrisation of artery
2.9
8.2
43
168
KBV00
NOMESCO Finland
Insertion of stent into ureter
34.5
8.1
10
*
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
11.3
7.9
14
13
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
46.4
7.8
9
*
C02AC05
ATC
moxonidine; oral
4.3
7.7
20
49
R4110
NOMESCO Finland
Physiotherapy
2.2
7.5
91
521
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
82.4
7.5
8
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
7.4
39
152
JAF30
NOMESCO Finland
Repair of umbilical hernia using prosthetic material
11.3
7.4
13
12
JJA30
NOMESCO Finland
Marsupialisation of cyst of liver
+∞
7.3
7
*
Q61.0
ICD-10 Finland
Congenital single renal cyst
+∞
7.3
7
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.2
7.3
20
51
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
7.3
84
471
3AC01, ,
NOMESCO Finland
16.3
7.3
11
7
C07AG02
ATC
carvedilol; oral
3.5
7.2
26
81
Z2446
NOMESCO Finland
Social worker
3.5
7.2
26
81
UJF32
NOMESCO Finland
Coloscopy
2.1
7.2
87
497
JN4AD
NOMESCO Finland
Body CT examination
2.6
7.1
44
187
137
Kela drug reimbursment
Uraemia requiring dialysis
14.3
7.0
11
8
J01MA12
ATC
levofloxacin; systemic
2.3
6.9
60
298
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.3
6.9
18
44
RD210, ,
NOMESCO Finland
9.7
6.9
13
14
Z49.2
ICD-10 Finland
Other dialysis
17.3
6.8
10
6
XX6KT
NOMESCO Finland
Other sclerotherapy
41.2
6.8
8
*
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
23.2
6.7
9
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
6.5
51
242
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
71.6
6.5
7
*
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.2
6.4
16
27
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
6.4
54
265
B03XA01
ATC
erythropoietin; parenteral
18.6
6.3
9
5
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.5
6.3
22
67
75310
ICD-8 Finland
Congenital anomalies of urinary system, Ren polycysticus bilateralis
+∞
6.3
6
*
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
27.4
6.3
8
*
A02BC05
ATC
esomeprazole; systemic
1.9
6.2
120
801
K83.0
ICD-10 Finland
Cholangitis
10.4
6.1
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
49
35
17.09
55.14
2.0
2.3
3.12
108.75
u/ml
0.49
49
35
54
73
9.12
39.37
8.6
3.1
1.91
1.48
mg/l
1.79
54
63
102
277
5.47
37.24
11.7
2.8
6.00
7.41
umol/l
0.64
96
247
211
1063
6.71
35.07
16.1
4.6
35.81
35.86
g/l
0.05
203
1005
40
43
10.85
34.50
1.8
1.3
—
—
—
0
0
38
38
11.58
34.45
1.7
1.1
284.84
295.56
u/ml
0.04
32
18
106
315
5.05
34.38
21.2
5.8
1.13
1.04
mmol/l
2.04
99
289
38
40
10.99
33.23
1.9
1.1
167.57
170.60
au/ml
0.05
14
14
61
115
6.66
32.72
2.9
3.3
235.33
2108.83
u/ml
0.86
54
99
61
133
5.71
27.88
12.7
4.0
23.36
24.38
mmol/l
2.02
61
133
200
1090
4.87
26.63
18.7
12.4
1.18
1.20
inr
0.17
167
892
71
188
4.85
25.77
19.4
8.6
—
—
—
0
0
40
62
7.47
25.55
1.6
1.2
—
—
—
0
0
34
18
21.58
23.32
1.2
1.2
—
—
—
0
0
74
233
4.07
21.06
13.1
4.0
7.36
7.39
ph
3.56
52
134
72
228
4.01
20.26
3.1
1.5
—
—
—
0
0
150
762
3.35
20.00
14.5
4.4
7.39
7.40
ph
1.67
120
527
149
768
3.26
19.12
5.0
2.6
63.76
70.00
u/l
0.32
142
712
26
15
19.14
17.34
3.6
1.1
—
—
—
0
0
76
276
3.50
17.19
3.2
1.5
—
—
—
0
0
23
10
25.11
16.75
6.0
3.0
0.57
0.60
mmol/l
—
23
10
191
1201
3.35
16.35
22.7
7.1
1.20
1.22
mmol/l
1.40
172
1032
25
38
7.19
16.06
1.8
1.1
—
—
—
0
0
20
6
35.97
15.99
1.1
1.0
—
—
—
0
0
80
313
3.27
15.92
3.1
1.7
—
—
—
0
0
179
1094
3.13
15.91
20.2
6.3
1.21
1.22
mmol/l
0.44
171
1002
19
5
40.81
15.61
1.1
1.0
—
—
—
0
0
74
282
3.29
15.32
2.9
4.5
3.73
24.83
ug/l
0.81
52
236
65
229
3.47
15.26
6.4
2.4
40.53
32.23
u/l
0.78
58
186
50
148
3.96
15.18
2.0
1.4
—
—
—
0
0
121
613
2.85
15.03
10.2
4.0
—
—
—
0
0
48
149
3.74
13.55
15.7
8.3
24.15
25.09
mmol/l
1.35
48
149
111
565
2.71
13.30
3.8
2.2
—
—
—
0
0
22
19
12.55
12.58
1.2
1.2
—
—
—
0
0
115
616
2.58
12.18
6.5
2.9
349.16
336.79
umol/l
0.64
107
539
74
319
2.86
12.05
14.7
6.6
104.11
104.05
mmol/l
0.03
74
319
111
588
2.57
12.00
3.1
2.3
2.47
3.07
mg/l
2.33
95
507
167
1075
2.60
11.86
4.6
2.7
—
—
estimate
—
0
0
16
7
24.25
11.72
2.2
1.7
—
—
—
0
0
130
753
2.48
11.47
4.1
2.3
—
—
—
0
0
109
583
2.52
11.43
7.4
3.9
—
0.17
—
0
6
168
1102
2.54
11.18
4.3
2.5
81.88
79.16
nmol/l
0.73
159
987
210
1539
3.07
11.12
10.9
3.3
83.62
46.79
u/l
3.85
202
1448
26
61
4.63
10.58
9.7
3.2
82.12
57.96
%
8.78
26
61
15
8
19.82
10.39
1.1
1.1
—
—
—
0
0
14
6
24.56
10.35
1.1
1.2
—
—
—
0
0
117
670
2.38
10.30
8.9
3.2
0.13
0.40
e6/l
2.65
95
474
71
327
2.62
9.98
3.0
2.0
—
—
—
0
0
130
789
2.32
9.90
9.2
3.3
13.43
121.18
e6/l
0.71
107
598
174
1203
2.41
9.66
12.8
6.2
0.53
0.57
e9/l
1.48
151
1018
78
382
2.50
9.61
6.0
3.0
1.15
2.97
e6/l
2.04
48
184
176
1226
2.41
9.56
12.8
6.3
1.59
1.86
e9/l
2.47
154
1074
181
1278
2.43
9.50
7.5
4.0
0.00
0.00
estimate
-0.00
42
275
22
49
4.82
9.50
10.5
2.7
83.59
57.87
%
8.68
22
49
174
1209
2.38
9.46
12.8
6.2
0.04
0.04
e9/l
1.50
151
1018
153
1014
2.27
9.20
6.6
3.6
6.24
6.18
ph
0.29
86
580
181
1289
2.39
9.15
7.5
4.0
0.00
5.72
estimate
0.50
40
284
177
1249
2.36
9.13
13.0
6.6
0.18
0.18
e9/l
0.07
156
1079
186
1342
2.43
9.10
15.3
9.9
4.18
3.97
e9/l
0.54
167
1163
182
1301
2.39
9.09
7.6
4.1
0.00
0.00
estimate
-0.00
42
261
139
891
2.23
9.01
11.1
4.1
50.40
84.40
e6/l
0.54
112
620
160
1093
2.25
8.77
6.4
3.1
139.07
112.17
ug/l
1.29
152
1016
126
789
2.18
8.51
13.0
6.0
—
—
—
0
0
67
325
2.44
8.30
1.4
1.3
—
—
—
0
0
59
272
2.52
8.14
4.1
3.4
1.74
1.77
%
0.07
52
248
159
1104
2.17
8.09
13.2
6.2
0.65
0.69
%
0.46
150
1019
116
714
2.15
8.08
9.6
6.6
—
—
—
0
0
29
90
3.51
8.08
3.7
2.5
20.62
20.83
s
0.08
29
83
159
1106
2.16
8.03
13.0
6.2
60.42
57.83
%
2.10
152
1042
159
1106
2.16
8.03
13.2
6.2
2.88
2.78
%
0.21
149
1022
159
1108
2.16
7.96
13.3
6.3
8.51
8.87
%
0.85
150
1028
50
216
2.64
7.86
4.7
3.2
58.20
69.95
e9/l
1.56
29
156
160
1128
2.12
7.64
13.3
6.3
25.10
27.39
%
1.92
151
1056
55
253
2.50
7.59
13.6
7.3
7.40
7.42
ph
1.07
24
153
54
252
2.45
7.20
13.6
7.3
-0.11
1.00
mmol/l
2.10
48
220
80
445
2.16
7.06
3.7
3.9
465.38
211.93
ng/l
0.40
69
345
26
84
3.33
6.81
2.0
3.8
1.32
2.18
ratio
0.65
11
46
27
92
3.16
6.49
2.1
4.2
49.55
31.05
mg/l
0.85
21
82
27
92
3.16
6.49
2.1
4.2
1740.91
105.18
mg/l
0.47
21
82
38
159
2.63
6.32
2.6
1.8
1.10
1.42
g/l
0.67
38
147
113
738
1.95
6.29
4.0
3.1
—
—
—
0
0
145
1041
1.91
5.97
22.9
12.1
0.00
0.00
e9/l
0.41
119
848
126
867
1.90
5.88
5.1
3.5
2.34
2.36
mmol/l
0.91
119
787
98
621
1.94
5.87
1.6
1.4
—
—
—
0
0
246
2222
4.03
5.86
42.1
15.6
22.65
22.54
mg/l
0.02
229
1806
62
337
2.11
5.68
1.4
1.2
—
—
—
0
0
9
8
11.60
5.33
1.2
1.0
1712.22
1253.25
miu/ml
—
9
8
20
64
3.31
5.32
3.6
2.9
2.69
1.55
index
0.36
13
33
119
827
1.82
5.20
6.5
4.0
5.87
8.75
mg/mmol
0.81
94
481
22
76
3.07
5.18
4.0
1.2
0.89
0.90
g/l
0.05
22
76
13
23
5.90
5.13
3.9
3.6
11.68
11.16
%
0.14
13
23
31
133
2.52
4.89
10.4
2.7
1.25
1.22
%
0.05
31
133
143
1065
1.78
4.84
2.5
2.1
94.03
97.58
pmol/l
0.48
82
529
45
229
2.17
4.83
1.9
1.4
—
—
—
0
0
115
804
1.78
4.83
5.9
3.4
37.24
47.42
mg/l
0.40
94
494
26
103
2.70
4.80
2.1
1.4
0.21
0.30
mg/l
—
8
40
107
735
1.79
4.75
2.0
1.7
20.34
21.74
nmol/l
0.48
95
616
54
298
2.03
4.69
1.8
1.4
—
—
—
0
0
38
184
2.25
4.60
1.9
2.4
—
—
—
0
0
7
5
14.34
4.60
1.9
1.0
—
—
—
0
0
17
54
3.30
4.57
8.9
2.5
11.15
9.17
pmol/l
0.22
17
54
30
132
2.44
4.50
10.6
2.7
0.71
0.60
%
0.53
30
132
117
839
1.73
4.38
6.0
3.2
6.75
7.41
mmol/l
0.98
107
687
85
557
1.79
4.36
6.5
4.0
1.02
1.02
kg/l
0.63
64
360
103
732
1.68
3.87
8.0
4.1
0.00
0.00
estimate
-0.00
39
262
128
965
1.66
3.82
2.8
2.2
—
—
—
0
0
6
6
10.20
3.51
1.7
1.2
—
—
—
0
0
61
385
1.77
3.47
1.9
1.7
1129.19
1204.57
nmol/l
0.33
51
284
13
43
3.13
3.30
1.0
1.0
—
—
—
0
0
126
973
1.58
3.24
7.2
3.9
0.00
0.01
estimate
0.80
37
230
55
344
1.76
3.21
1.6
1.4
234.29
618.88
titre
—
7
89
7
11
6.51
3.20
2.0
2.0
134.79
63.75
ug/l
—
7
11
16
61
2.73
3.20
1.3
1.6
—
—
—
0
0
9
20
4.62
3.14
1.2
3.0
3.69
3.08
nmol/l
—
9
20
12
36
3.45
3.06
1.0
1.0
—
—
—
0
0
75
524
1.61
2.88
3.7
2.6
2.45
2.45
mmol/l
0.12
70
473
26
134
2.05
2.72
1.4
1.2
—
—
—
0
0
6
10
6.11
2.71
1.5
2.6
3.83
4.29
ug/l
—
6
10
12
41
3.02
2.66
4.1
2.6
3.26
4.91
e9/l
2.06
12
41
133
1072
1.50
2.63
2.6
2.0
1.10
1.33
mmol/l
5.92
112
895
6
11
5.56
2.56
3.8
2.9
1.00
0.64
index
—
6
11
243
2273
2.47
2.53
31.3
13.8
—
—
—
0
0
10
32
3.21
2.46
2.1
1.1
—
—
—
0
0
47
303
1.68
2.45
2.9
2.2
138.05
123.73
ug/g
0.15
40
236
96
734
1.49
2.41
1.9
2.1
132.21
178.86
u/l
0.71
91
693
9
28
3.29
2.33
1.0
2.7
—
—
—
0
0
8
23
3.56
2.29
1.1
1.2
—
—
—
0
0
6
13
4.70
2.28
1.0
1.6
—
—
—
0
0
38
236
1.72
2.27
1.4
1.5
—
—
—
0
0
20
102
2.04
2.17
2.5
1.9
—
—
—
0
0
8
25
3.27
2.11
1.1
1.4
—
—
—
0
0
23
125
1.92
2.10
2.2
1.6
—
—
—
0
0
45
301
1.60
2.04
2.3
3.2
4.44
5.46
e9/l
0.45
39
264
17
84
2.10
2.01
2.1
2.0
145.59
314.23
ug/l
1.26
17
79
15
71
2.18
1.96
6.0
3.1
7.41
7.41
ph
0.49
15
71
38
246
1.64
1.96
2.0
1.7
—
—
—
0
0
0
53
0.00
1.89
0.0
4.6
—
23.45
—
0
38
11
46
2.45
1.88
9.3
2.6
—
—
—
0
0
6
17
3.59
1.85
5.3
2.9
814.67
595.30
ml
—
6
10
69
518
1.46
1.84
1.8
1.4
2.57
2.35
g/l
0.37
48
295
71
536
1.45
1.84
2.4
1.8
1.79
1.28
mg/l
0.82
55
435
249
2400
2.59
1.84
57.1
24.2
6.48
6.53
e9/l
0.16
244
2352
22
124
1.85
1.82
3.4
2.1
0.00
0.02
estimate
—
7
43
11
47
2.40
1.80
6.9
3.0
4.94
5.07
kpa
0.30
11
47
11
47
2.40
1.80
6.9
3.0
8.75
8.66
kpa
0.04
11
47
14
67
2.15
1.79
1.5
1.3
105.40
300.58
miu/ml
—
5
31
31
195
1.67
1.79
8.6
4.0
—
—
—
0
0
7
24
2.97
1.73
1.7
2.0
91.11
89.46
%
—
7
24
234
2202
1.76
1.72
7.1
5.4
5.72
5.96
mmol/l
2.65
220
2044
34
222
1.61
1.71
5.7
4.1
0.86
1.00
%
0.17
14
67
6
19
3.21
1.67
1.0
3.6
1188.67
1091.26
mg
—
6
19
6
19
3.21
1.67
4.7
2.6
15.00
13.82
index
—
6
11
32
208
1.62
1.64
5.8
4.5
0.00
0.11
%
—
10
47
32
208
1.62
1.64
5.2
3.9
0.69
0.62
%
0.08
13
55
5
14
3.62
1.62
5.8
2.6
474.80
493.89
min
—
5
9
5
14
3.62
1.62
1.0
1.0
—
—
—
0
0
109
903
1.36
1.62
3.2
3.8
73.99
92.13
ng/l
0.08
79
651
6
20
3.05
1.59
1.0
1.3
—
—
—
0
0
71
554
1.39
1.51
7.5
5.2
—
—
—
0
0
12
59
2.08
1.46
4.8
2.4
57.17
60.90
%
0.54
12
59
18
103
1.80
1.45
1.4
1.6
—
—
—
0
0
6
22
2.77
1.44
1.7
1.5
23.73
37.57
ng/l
—
6
22
15
81
1.91
1.43
1.5
1.3
191.33
309.54
ug/g
—
9
47
230
2175
1.59
1.38
9.0
6.7
37.78
39.33
mmol/mol
2.73
222
2040
6
135
0.43
1.31
1.3
2.3
12.40
13.24
nmol/l
—
6
128
236
2250
1.66
1.31
7.2
5.4
4.51
4.72
mmol/l
2.78
224
2096
5
18
2.81
1.29
7.8
1.2
28.90
21.16
umol/l
—
5
10
238
2279
1.66
1.22
8.0
6.2
2.58
2.75
mmol/l
2.52
223
2115
34
241
1.47
1.22
4.2
2.0
0.00
0.06
estimate
—
6
52
30
210
1.49
1.15
6.0
4.2
0.40
0.20
%
—
10
55
19
120
1.63
1.12
2.2
2.3
—
—
—
0
0
5
21
2.41
1.09
3.6
2.5
—
—
—
0
0
84
706
1.28
1.06
5.4
3.4
0.00
0.00
estimate
-0.00
36
225
11
60
1.87
1.04
1.7
1.2
—
—
—
0
0
7
35
2.03
1.01
1.0
1.3
—
—
—
0
0
7
35
2.03
1.01
1.0
1.3
—
—
—
0
0
7
35
2.03
1.01
1.0
1.3
—
—
—
0
0
7
35
2.03
1.01
1.0
1.3
—
—
—
0
0
14
84
1.71
1.00
4.9
2.9
141.22
290.37
mg/l
—
9
30
5
23
2.20
0.98
1.4
1.7
6.58
4.33
mg/l
—
5
23
0
30
0.00
0.98
0.0
1.7
—
—
—
0
0
11
62
1.81
0.95
1.4
1.7
5.20
4.48
iu/l
—
6
29
6
27
2.25
0.94
2.7
1.2
95.33
101.11
pmol/l
—
6
27
222
2118
1.37
0.92
5.8
5.8
1.94
1.92
mu/l
0.09
211
1955
12
192
0.61
0.90
1.4
1.4
—
—
—
0
0
8
42
1.93
0.89
2.3
1.3
—
—
—
0
0
15
96
1.60
0.86
5.1
3.2
—
—
—
0
0
18
122
1.51
0.82
1.1
1.1
—
—
—
0
0
194
1831
1.25
0.78
4.7
4.6
15.24
14.81
pmol/l
1.74
186
1681
6
34
1.78
0.77
2.7
1.2
—
—
—
0
0
16
108
1.51
0.75
1.3
1.2
—
—
—
0
0
5
25
2.02
0.73
3.6
1.9
—
—
—
0
0
13
86
1.54
0.67
2.2
3.1
—
—
—
0
0
231
2243
1.32
0.59
7.2
5.3
1.53
1.52
mmol/l
0.10
216
2077
6
35
1.73
0.58
2.3
1.9
—
—
—
0
0
6
36
1.68
0.57
2.2
1.6
—
—
—
0
0
44
515
0.82
0.52
1.5
1.3
12.29
37.13
iu/ml
—
10
167
56
493
1.17
0.45
1.6
1.8
499.98
28058009.10
pmol/l
0.50
48
417
16
207
0.76
0.44
1.6
1.4
—
—
—
0
0
15
113
1.35
0.43
1.5
1.6
20.80
4.75
iu/ml
—
5
28
220
2141
1.20
0.42
5.9
4.5
1.12
1.27
mmol/l
4.98
203
1971
22
177
1.27
0.42
1.4
1.2
56.42
150.96
u/ml
—
9
69
5
33
1.53
0.41
1.4
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
72.13
—
0
15
0
16
0.00
0.41
0.0
1.1
—
0.45
—
0
8
0
18
0.00
0.40
0.0
1.9
—
7.63
—
0
18
83
901
0.88
0.38
3.6
3.4
—
—
—
0
0
12
89
1.37
0.38
1.1
1.3
—
—
—
0
0
5
36
1.40
0.38
1.8
2.1
32.00
31.50
pg
—
5
36
37
321
1.18
0.36
1.4
1.3
—
—
—
0
0
6
41
1.47
0.36
1.0
1.1
—
—
—
0
0
6
41
1.47
0.36
1.0
1.1
—
—
—
0
0
64
580
1.14
0.36
1.4
1.2
4.72
1.46
u/ml
0.44
12
169
20
167
1.21
0.29
1.3
1.3
—
—
—
0
0
36
318
1.15
0.29
4.0
3.2
0.96
0.78
ug/l
0.52
26
206
11
85
1.31
0.28
1.3
1.1
—
—
—
0
0
19
159
1.21
0.27
1.7
2.0
3.54
3.48
mmol/l
—
10
120
18
214
0.83
0.27
4.8
2.4
6.05
6.11
ph
—
10
142
5
72
0.69
0.26
1.0
1.2
1.64
1.58
g/l
—
5
72
5
38
1.32
0.23
2.2
1.2
—
—
nmol/l
—
0
0
5
41
1.22
0.22
3.0
2.1
0.70
0.87
%
—
5
26
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
8.00
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
0.00
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
4.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
0.09
—
0
7
24
213
1.14
0.19
14.6
3.9
7.34
7.33
ph
0.03
19
145
14
119
1.19
0.18
1.3
1.3
35.04
27.62
iu/l
0.24
14
97
25
227
1.11
0.15
1.5
1.6
—
—
—
0
0
44
469
0.93
0.14
1.5
1.3
1.52
13.64
u/ml
3.15
20
186
17
153
1.12
0.11
1.4
1.4
—
28.31
—
0
14
11
125
0.87
0.10
1.0
1.1
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
6
55
1.09
0.09
1.0
1.2
—
—
—
0
0
6
58
1.04
0.08
1.0
1.2
—
—
—
0
0
6
58
1.04
0.08
1.0
1.2
—
—
—
0
0
7
66
1.06
0.08
1.0
1.1
—
—
—
0
0
7
85
0.82
0.07
16.9
10.0
—
—
—
0
0
8
95
0.84
0.07
1.1
1.1
—
—
—
0
0
19
184
1.04
0.00
1.4
1.2
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.01
—
0
5
5
52
0.96
-0.00
1.2
1.3
11.82
12.98
u/l
—
5
39
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
124.00
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
73.51
—
0
8
8
81
0.99
-0.00
1.3
1.3
—
3.04
—
0
14
0
5
0.00
-0.00
0.0
1.6
—
64.20
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.84
-0.00
1.2
1.5
224.60
310.71
mu/l
—
5
52
6
60
1.00
-0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
166.94
—
0
8
0
9
0.00
-0.00
0.0
12.7
—
1055.33
—
0
9
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_CYSTIC_DISEASE_OF_LIVER – Cystic disease of liver

GWS hits: 12

This endpoint is excluded (different definition than used in FinnGen).