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Lumbosacral root disorders, not elsewhere classified

DOID EFO Endpoint Browser PheWeb

G6_LSROOT

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G54.4
  • Hospital discharge: ICD-9 — 3534
  • Cause of death: ICD-10 — G54.4
  • Cause of death: ICD-9 — 3534

2 out of 7 registries used, show all original rules.

489

4. Check minimum number of events

None

489

5. Include endpoints

None

489

6. Filter based on genotype QC (FinnGen only)

445

Control definitions (FinnGen only)

Control exclude
G6_NERPLEX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G54
Name in latin
Morbositates radicum nervorum lumbosacralium non alibi classificatae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3586 1888 1683
Only index persons 3295 1778 1517
Unadjusted period prevalence (%)
Whole population 0.05 0.05 0.05
Only index persons 0.06 0.07 0.06
Median age at first event (years)
Whole population 57.09 56.62 57.51
Only index persons 56.44 55.99 56.96

-FinnGen-

Key figures

All Female Male
Number of individuals 445 257 188
Unadjusted period prevalence (%) 0.09 0.09 0.09
Median age at first event (years) 54.99 52.43 58.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
453
Matched controls
4530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XA402
NOMESCO Finland
ENMG
184.6
307.7
238
27
G54.4
ICD-10 Finland
Lumbosacral root disorders, not elsewhere classified
12967.2
307.7
374
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
9.9
126.6
201
339
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
7.9
107.8
226
506
N03AX16
ATC
[U] pregabalin
7.8
107.6
245
596
M48.0
ICD-10 Finland
Spinal stenosis
8.1
93.9
164
298
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
7.2
83.6
162
325
N03AX12
ATC
[U] gabapentin; oral
6.7
80.3
171
375
3534A
ICD-9 Finland
Nerve root and plexus disorders, Lumbosacral root lesions, not elsewhere classified[RADICULOPATHIA LUMBOSACRALIS]
+∞
71.8
67
*
M54.4
ICD-10 Finland
Lumbago with sciatica
5.8
70.8
182
469
M54.1
ICD-10 Finland
Radiculopathy
11.5
67.9
76
78
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
8.9
63.3
88
120
ZYC05, ,
SPAT
16.8
58.8
51
34
G56.0
ICD-10 Finland
Carpal tunnel syndrome
10.4
55.6
66
73
N06AA09
ATC
amitriptyline; systemic
6.0
50.6
105
217
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
7.3
50.3
82
133
M54.5
ICD-10 Finland
Low back pain
4.1
48.0
258
1112
N06AX21
ATC
duloxetine; oral
5.3
46.4
112
264
G55.1*M51.9
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders (M50-M51+)
174.3
45.7
47
*
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
8.1
45.7
66
93
N02AX02
ATC
tramadol; systemic, rectal
4.0
44.7
288
1384
Z01.9
ICD-10 Finland
Special examination, unspecified
6.5
43.4
79
143
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
4.5
40.2
119
329
ACC51
NOMESCO Finland
Release of median nerve
410.4
38.7
38
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
5.1
38.4
93
218
L03
ICPC
Low back symptom/complaint
3.5
35.9
197
825
Z50.1
ICD-10 Finland
Other physical therapy
6.7
35.6
61
103
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
4.7
35.2
94
238
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
14.9
35.1
32
23
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
14.9
35.1
32
23
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
6.8
34.5
58
96
N02AA05
ATC
oxycodone; systemic
3.7
34.0
145
515
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
38.4
33.4
42
12
M54.9
ICD-10 Finland
Dorsalgia, unspecified
4.3
33.2
101
282
L28
ICPC
Limited function/disability (L)
3.5
32.3
148
548
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
11.4
30.8
33
31
M47.9
ICD-10 Finland
Spondylosis, unspecified
9.1
30.0
38
45
M43.1
ICD-10 Finland
Spondylolisthesis
6.4
28.5
50
86
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
7.8
28.4
41
57
M17.1
ICD-10 Finland
Other primary gonarthrosis
3.2
27.9
158
658
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.9
27.6
213
1052
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
8.0
27.6
39
53
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
7.4
27.2
41
60
NE1AA, ,
SPAT
10.6
26.8
30
30
R29
ICPC
Respiratory symptom/complaint other
4.7
26.2
66
158
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
25.8
254
1412
N02BF01
ATC
gabapentin; oral
4.1
25.6
80
226
Z76.0
ICD-10 Finland
Issue of repeat prescription
2.9
25.1
183
867
WX702
NOMESCO Finland
Supraglottic ventilation device
5.0
25.1
59
133
A29
ICPC
General symptom/complaint other
3.4
25.0
109
385
M01AH01
ATC
celecoxib; oral
3.2
24.7
128
502
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
30.1
23.5
31
11
A02BC05
ATC
esomeprazole; systemic
2.6
22.9
237
1327
A02BC03
ATC
lansoprazole; oral
2.7
22.8
184
910
M79.0
ICD-10 Finland
Rheumatism, unspecified
6.9
22.5
36
56
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.7
22.2
81
254
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
9.0
22.1
28
33
M79.6
ICD-10 Finland
Pain in limb
2.6
22.0
247
1429
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.7
22.0
43
82
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
6.2
21.4
38
66
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.9
21.4
50
112
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
4.1
21.0
62
167
N06AX16
ATC
venlafaxine; oral
3.2
20.7
97
355
M03BC01
ATC
orphenadrine (citrate); systemic
2.7
20.2
143
656
N02BF02
ATC
pregabalin; oral
4.2
19.8
56
146
S02.5
ICD-10 Finland
Fracture of tooth
6.7
19.5
32
51
K30
ICD-10 Finland
Functional dyspepsia
3.3
19.5
83
286
N02AJ06
ATC
codeine and paracetamol; systemic
2.5
19.5
235
1382
M01AH05
ATC
etoricoxib; oral
2.6
19.3
327
2242
M03BX02
ATC
tizanidine; oral
2.6
19.3
317
2142
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
6.9
19.0
30
46
M25.5
ICD-10 Finland
Pain in joint
2.5
18.6
187
1007
A06AD11
ATC
lactulose; oral
3.0
18.5
98
383
Z02.7
ICD-10 Finland
Issue of medical certificate
3.9
18.5
58
163
XG410
NOMESCO Finland
Flow-volume spirometry
5.2
18.4
39
80
M54.3
ICD-10 Finland
Sciatica
4.5
18.4
47
113
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.5
18.2
71
231
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
6.8
18.1
29
45
9211
FHL
Exploration or removal of diskusprolapse
7.3
18.0
27
39
WX704
NOMESCO Finland
Intubation
3.9
18.0
58
166
M01AC06
ATC
meloxicam; systemic, rectal
2.4
17.6
210
1214
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.5
17.0
151
763
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
36.6
16.8
21
6
R52.2
ICD-10 Finland
Other chronic pain
5.6
16.8
33
63
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
5.6
16.8
33
63
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.7
16.6
56
165
Z00.6
ICD-10 Finland
Examination for normal comparison and control in clinical research programme
13.5
16.4
28
22
M01AB05
ATC
diclofenac; systemic, rectal
2.5
16.4
333
2391
N03AX09
ATC
lamotrigine; oral
4.9
15.9
36
78
A02BC02
ATC
pantoprazole; systemic
2.5
15.9
349
2575
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
15.4
164
892
NG1EA, ,
SPAT
13.7
15.4
26
20
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
46.7
15.2
18
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.5
15.1
120
572
M47.82
ICD-10 Finland
Other spondylosis, cervical region
4.7
15.0
36
82
UJD10, ,
SPAT
5.8
15.0
28
51
M01AH02
ATC
rofecoxib; oral
2.9
14.9
81
319
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
6.4
14.8
25
41
M01AE02
ATC
naproxen; oral, rectal
2.2
14.7
283
1942
S29
ICPC
Skin symptom/complaint other
2.4
14.6
120
581
M70.6
ICD-10 Finland
Trochanteric bursitis
2.7
14.4
87
362
J01MA02
ATC
ciprofloxacin; systemic
2.2
14.4
206
1257
OAB36, ,
SPAT
5.0
14.2
31
65
XA420
NOMESCO Finland
Extensive sleep examination
15.1
14.2
23
16
L29
ICPC
Musculoskeletal sympt/complt other
3.1
14.2
63
221
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.1
14.2
66
238
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.9
14.2
73
279
GD1AA, ,
SPAT
2.6
14.0
100
452
M54.8
ICD-10 Finland
Other dorsalgia
4.7
14.0
33
74
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
5.4
13.8
28
55
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.7
13.6
81
334
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.2
13.5
153
847
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.8
13.5
76
305
G57.3
ICD-10 Finland
Lesion of lateral popliteal nerve
22.0
13.4
19
9
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
13.4
202
1249
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.5
13.3
94
422
N03AE01
ATC
clonazepam; systemic
4.0
13.3
39
104
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.9
13.3
30
65
J01FA09
ATC
clarithromycin; systemic
2.2
13.1
163
934
GX2C5
NOMESCO Finland
Short-lasting oximetry
19.8
13.0
19
10
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
12.7
87
385
3534B
ICD-9 Finland
Nerve root and plexus disorders, Lumbosacral root lesions, not elsewhere classified[SYNDROMA CAUDAE EQUINAE]
+∞
12.6
12
*
H02AB06
ATC
prednisolone; systemic
2.0
12.6
239
1598
M01AE11
ATC
tiaprofenic acid; oral, rectal
4.4
12.5
32
77
K29
ICPC
Cardiovascular sympt/complt other
4.0
12.4
36
95
M01AX05
ATC
glucosamine; oral
2.3
12.4
115
582
R05
ICPC
Cough
2.2
12.3
139
763
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.4
12.3
47
150
GX1E5, ,
SPAT
9.1
12.2
25
29
M79.7
ICD-10 Finland
Fibromyalgia
4.6
12.1
29
66
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.4
12.0
45
142
G45.4
ICD-10 Finland
Transient global amnesia
5.6
11.9
23
43
M01AX17
ATC
nimesulide; oral
2.2
11.9
131
711
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
11.9
104
513
A28
ICPC
Limited function/disability NOS
2.3
11.8
106
528
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.4
11.6
91
427
JN3AE, ,
SPAT
3.7
11.5
38
110
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
4.3
11.5
30
73
35399
ICD-8 Finland
Sciatica
+∞
11.5
11
*
R1280
NOMESCO Finland
Evaluation of the need for vocational rehabilitation
+∞
11.5
11
*
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.6
11.5
71
298
EC1VA, ,
NOMESCO Finland
3.8
11.4
36
101
R51.80
ICD-10 Finland
Headache
2.5
11.4
83
377
N05CD07
ATC
temazepam; oral
2.6
11.3
70
294
R07.3
ICD-10 Finland
Other chest pain
2.7
11.2
64
257
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.0
11.2
33
88
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
11.1
107
549
ND2AA, ,
SPAT
3.5
10.9
39
119
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.4
10.9
81
370
KMAK, ,
NOMESCO Finland
1.9
10.9
235
1613
M54.2
ICD-10 Finland
Cervicalgia
3.0
10.9
51
184
HA1AA, ,
SPAT
5.3
10.9
22
43
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.9
10.9
219
1470
B01AB10
ATC
tinzaparin; parenteral
2.6
10.9
72
312
M50.3
ICD-10 Finland
Other cervical disc degeneration
10.0
10.9
21
22
A01
ICPC
Pain general/multiple sites
2.7
10.8
63
256
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
18.4
10.8
16
9
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
13.3
10.7
18
14
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
10.7
63
257
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
3.3
10.7
41
131
ABC99
NOMESCO Finland
Other decompressive operation on spinal cord or nerve root
61.5
10.7
12
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.4
10.6
40
127
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
10.6
240
1672
L15
ICPC
Knee symptom/complaint
2.1
10.5
134
765
G56.2
ICD-10 Finland
Lesion of ulnar nerve
16.5
10.4
16
10
S02.51
ICD-10 Finland
Fracture of tooth, open
2.6
10.4
67
286
J01DB01
ATC
cefalexin; oral
2.4
10.4
382
3144
L86
ICPC
Back syndrome with radiating pain
3.4
10.4
38
118
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
33.4
10.4
13
*
R06AE07
ATC
cetirizine; oral
1.9
10.3
204
1353
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
10.3
154
929
K59.09
ICD-10 Finland
Constipation, unspecified
3.0
10.1
46
163
J01DA01
ATC
[U] cefalexin
1.9
10.1
289
2158
S18
ICPC
Laceration/cut
1.9
10.1
234
1632
M96.1
ICD-10 Finland
Postlaminectomy syndrome, not elsewhere classified
15.0
10.1
16
11
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
10.0
63
266
R96
ICPC
Asthma
2.6
9.9
60
249
P03
ICPC
Feeling depressed
2.8
9.8
51
195
G54.0
ICD-10 Finland
Brachial plexus disorders
13.8
9.7
16
12
XQ800
NOMESCO Finland
Prick test
3.1
9.7
41
139
Z71.9
ICD-10 Finland
Counselling, unspecified
2.8
9.7
52
202
G57.8
ICD-10 Finland
Other mononeuropathies of lower limb
56.2
9.7
11
*
D29
ICPC
Digestive symptom/complaint other
4.8
9.6
22
48
H57.1
ICD-10 Finland
Ocular pain
4.0
9.5
27
70
S06.0
ICD-10 Finland
Concussion
2.5
9.5
64
279
G51.0
ICD-10 Finland
Bell palsy
+∞
9.4
9
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
5.1
9.4
20
41
Z01.2
ICD-10 Finland
Dental examination
1.9
9.3
215
1486
N06AX11
ATC
mirtazapine; oral
1.9
9.3
167
1066
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
9.3
159
999
ZXA05
NOMESCO Finland
Left side
2.0
9.2
122
701
UKC02
NOMESCO Finland
Cystoscopy
2.2
9.2
89
454
1220
FHL
Arthroscopy
3.8
9.1
28
77
ZX109, ,
SPAT
11.8
9.1
16
14
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.3
9.1
79
386
WZA90
NOMESCO Finland
Other medical or dental certificate
2.0
9.1
115
651
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
7.7
9.0
20
27
S59
ICPC
Skin, Other therap proced/minor surg NEC
7.1
8.9
21
31
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
12.9
8.9
15
12
R03DC03
ATC
montelukast; oral
2.2
8.9
85
432
R52.9
ICD-10 Finland
Pain, unspecified
2.5
8.9
60
262
M01AB16
ATC
aceclofenac; oral
4.3
8.8
23
56
N02BE01
ATC
paracetamol; systemic, rectal
2.7
8.8
414
3603
TAB20
NOMESCO Finland
Epidural puncture
14.4
8.7
14
10
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
2.8
8.7
46
177
UJF32
NOMESCO Finland
Coloscopy
1.9
8.7
137
835
M15.8
ICD-10 Finland
Other polyarthrosis
4.9
8.7
19
40
XG405, ,
SPAT
11.9
8.6
15
13
N05CF01
ATC
zopiclone; oral
1.9
8.6
163
1053
R52.1
ICD-10 Finland
Chronic intractable pain
16.7
8.6
13
8
J01MA12
ATC
levofloxacin; systemic
2.1
8.6
98
533
ZYC01, ,
SPAT
2.5
8.5
56
241
NH3FA, ,
SPAT
20.5
8.5
12
6
R42
ICD-10 Finland
Dizziness and giddiness
2.0
8.5
117
680
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
91.7
8.4
9
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.9
8.4
122
722
G54.2
ICD-10 Finland
Cervical root disorders, not elsewhere classified
+∞
8.4
8
*
L16
ICPC
Ankle symptom/complaint
2.4
8.3
63
290
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
4.4
8.3
21
50
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
4.4
8.3
21
50
7245A
ICD-9 Finland
Other and unspecified disorders of back, Backache, unspecified
14.8
8.2
13
9
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
14.8
8.2
13
9
K10.3
ICD-10 Finland
Alveolitis of jaws
3.5
8.2
29
88
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.5
8.2
29
88
ABC66
NOMESCO Finland
Decompression of lumbal spinal channel
34.0
8.1
10
*
D07AD01
ATC
clobetasol; topical
2.1
8.1
88
469
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.2
8.1
73
362
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
8.1
107
613
G50.1
ICD-10 Finland
Atypical facial pain
22.5
8.0
11
5
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
4.4
8.0
20
47
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
8.0
125
756
ZY010
NOMESCO Finland
Hospital outpatient
3.4
7.9
28
85
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
7.9
319
2556
R03BA01
ATC
beclometasone; inhalant
2.2
7.9
72
358
R5140
NOMESCO Finland
Monitoring the use of the aid
2.3
7.9
64
303
R43
ICPC
Respiratory, Other diagnostic procedure
8.7
7.9
16
19
N04BC05
ATC
pramipexole; oral
2.6
7.9
47
193
SFA10
NOMESCO Finland
One-surface restoration
1.8
7.9
251
1878
P01AB01
ATC
metronidazole; oral, rectal
1.8
7.9
194
1349
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
7.8
320
2570
M35.7
ICD-10 Finland
Hypermobility syndrome
9.7
7.8
15
16
S76
ICPC
Skin infection other
3.0
7.8
35
123
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
7.8
111
650
M01AE01
ATC
ibuprofen; systemic, rectal
2.5
7.8
409
3582
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
15.4
7.8
12
8
L08
ICPC
Shoulder symptom/complaint
1.9
7.7
112
660
D01
ICPC
Abdominal pain/cramps general
2.3
7.7
62
292
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.7
7.7
249
1865
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.8
7.7
39
147
ZX100
NOMESCO Finland
Oral
6.9
7.7
18
27
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
8.2
7.7
16
20
NH1FA, ,
SPAT
18.7
7.6
11
6
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
3.9
7.6
22
58
L17
ICPC
Foot/toe symptom/complaint
1.8
7.6
144
924
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.8
7.6
23
63
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
3.8
7.6
23
63
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.9
7.5
37
137
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.5
7.5
50
216
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
4.4
7.5
19
45
H13
ICPC
Plugged feeling ear
1.9
7.5
103
595
AA1AD
NOMESCO Finland
CT of head and brain
1.8
7.5
144
927
M22.4
ICD-10 Finland
Chondromalacia patellae
4.5
7.5
18
41
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.9
7.4
22
59
S04
ICPC
Lump/swelling localized
2.4
7.4
55
250
R35
ICD-10 Finland
Polyuria
2.6
7.4
43
174
M01AB55
ATC
diclofenac, combinations; oral
2.7
7.4
41
162
WX204
NOMESCO Finland
Axillary plexus blockaced
3.7
7.4
23
64
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
2.5
7.4
46
193
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.5
7.3
47
200
M02AA07
ATC
piroxicam; topical
1.8
7.3
167
1130
ACC53
NOMESCO Finland
Release of ulnar nerve
+∞
7.3
7
*
XF404
NOMESCO Finland
Ambulatory ECG
2.4
7.3
51
226
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
7.3
133
843
B01AB05
ATC
enoxaparin; parenteral
1.8
7.2
155
1029
R03AC02
ATC
salbutamol; inhalant
1.7
7.2
251
1906
J01CA04
ATC
amoxicillin; systemic
1.9
7.2
360
3032
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
7.2
69
350
QXB99, ,
SPAT
3.9
7.2
21
56
M24.2
ICD-10 Finland
Disorder of ligament
8.1
7.2
15
19
N27
ICPC
Fear of neurological disease other
6.2
7.1
18
30
B01AX05
ATC
fondaparinux; parenteral
12.3
7.1
12
10
NA3AA, ,
SPAT
3.3
7.1
27
86
R2110
NOMESCO Finland
Giving the first information
2.8
7.1
36
136
SFA00
NOMESCO Finland
Small restoration
2.1
7.1
70
359
C03CA01
ATC
furosemide; systemic
1.8
7.1
148
975
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
4.5
7.0
17
39
R05FA02
ATC
opium derivatives and expectorants; systemic
1.7
7.0
191
1354
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
3.3
7.0
26
82
L13
ICPC
Hip symptom/complaint
1.9
6.9
100
588
R09
ICPC
Sinus symptom/complaint
2.5
6.9
44
187
N42.9
ICD-10 Finland
Disorder of prostate, unspecified
6.9
6.9
16
24
A04
ICPC
Weakness/tiredness general
2.1
6.9
73
385
M77.4
ICD-10 Finland
Metatarsalgia
2.7
6.8
37
145
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.5
6.8
23
68
ZXA00
NOMESCO Finland
Right side
1.8
6.8
123
776
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.1
6.8
73
387
K59.9
ICD-10 Finland
Functional intestinal disorder, unspecified
7.3
6.8
15
21
J01EA01
ATC
trimethoprim; systemic
1.8
6.7
123
777
JAH01
NOMESCO Finland
Laparoscopy
3.2
6.7
26
84
R06AE09
ATC
levocetirizine; oral
2.1
6.7
65
331
J01AA04
ATC
lymecycline; systemic
2.2
6.7
60
296
L01
ICPC
Neck symptom/complaint
2.0
6.7
74
396
F29
ICPC
Eye symptom/complaint other
2.3
6.7
55
262
C07AB07
ATC
bisoprolol; oral
1.7
6.6
235
1778
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
12.5
6.6
11
9
Z04.3
ICD-10 Finland
Examination and observation following other accident
4.3
6.6
17
41
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
6.6
171
1193
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
6.5
94
551
Z98.8
ICD-10 Finland
Other specified postsurgical states
7.6
6.5
14
19
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
4.2
6.4
17
42
-50
ICPC
Medication/prescr/renewal
3.4
6.4
23
71
J01AA02
ATC
doxycycline; systemic
1.8
6.3
358
3051
ZX108, ,
SPAT
11.2
6.3
11
10
M77.9
ICD-10 Finland
Enthesopathy, unspecified
3.9
6.3
18
47
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.9
6.3
18
47
K02.1
ICD-10 Finland
Caries of dentine
1.6
6.3
254
1976
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
6.3
42
182
M89.0
ICD-10 Finland
Algoneurodystrophy
18.3
6.3
9
5
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
6.3
69
368
G58.8
ICD-10 Finland
Other specified mononeuropathies
+∞
6.3
6
*
R51
NOMESCO Finland
Aids services
+∞
6.3
6
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.8
6.3
19
52
R06AX22
ATC
ebastine; oral
1.9
6.3
80
450
7240B
ICD-9 Finland
Other and unspecified disorders of back, Spinal stenosis, other than cervical[STENOSIS CANALIS SPINALIS LUMBOSACRALIS]
27.1
6.2
8
*
RTGOM, ,
NOMESCO Finland
27.1
6.2
8
*
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
5.9
6.2
16
28
Y96.9
ICD-10 Finland
Unspecified type of accident
5.9
6.2
16
28
K07
ICPC
Swollen ankles/oedema
2.9
6.2
29
105
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
7.8
6.2
13
17
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.9
6.1
18
48
H29
ICPC
Ear symptom/complaint other
2.1
6.1
61
313
F34.1
ICD-10 Finland
Dysthymia
3.2
6.1
24
78
C10AA05
ATC
atorvastatin; oral
1.6
6.1
205
1519
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.4
6.0
43
192
XG460
NOMESCO Finland
Short time oxymetry
5.7
6.0
16
29
G03DC03
ATC
lynestrenol; oral
5.7
6.0
16
29
M23.3
ICD-10 Finland
Other meniscus derangements
6.2
6.0
15
25
M20.2
ICD-10 Finland
Hallux rigidus
3.2
6.0
24
79

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
236
1246
2.87
26.76
10.9
6.4
—
—
—
0
0
69
171
4.58
26.20
3.0
1.8
—
—
—
0
0
113
449
3.02
20.96
4.0
2.8
7.51
9.00
umol/l
0.29
104
403
110
514
2.51
14.41
5.1
3.6
5.63
5.65
e9/l
0.00
103
455
136
734
2.22
12.61
1.4
1.3
15.10
34.49
iu/ml
3.11
51
231
272
1905
2.07
12.58
11.2
13.3
1.15
1.24
inr
2.76
251
1568
125
654
2.26
12.49
1.4
1.3
14.18
14.46
u/ml
0.01
31
268
265
1843
2.06
12.44
6.0
6.2
1.22
1.21
mmol/l
0.25
251
1704
211
1355
2.04
12.32
4.5
3.3
31.90
31.77
u/l
0.02
206
1285
84
381
2.48
11.54
2.0
2.0
0.00
0.04
estimate
—
6
78
73
313
2.59
11.27
2.3
2.2
5.93
6.06
ph
0.74
67
204
278
2047
1.93
10.19
6.2
7.2
1.21
1.21
mmol/l
0.24
257
1771
227
1575
1.88
9.89
4.5
3.6
29.83
70.86
ng/l
0.61
187
1149
306
2342
1.94
9.80
5.4
4.9
6.59
6.66
mmol/l
0.25
298
2232
55
231
2.57
8.81
2.4
2.5
11.20
18.82
au/ml
—
5
17
256
1902
1.80
8.44
6.3
6.3
27.78
27.14
%
0.43
250
1798
252
1869
1.79
8.30
6.3
6.2
3.07
2.80
%
1.30
243
1744
251
1871
1.77
8.02
6.4
6.3
9.01
9.05
%
0.08
243
1750
251
1872
1.76
8.00
6.3
6.3
0.72
0.69
%
0.29
244
1742
185
1266
1.78
7.93
4.3
4.1
7.40
7.40
ph
0.53
165
898
56
250
2.41
7.88
5.7
9.7
24.64
24.55
mmol/l
0.07
56
245
273
2093
1.77
7.83
6.5
6.5
0.20
0.19
e9/l
0.48
255
1818
18
27
6.89
7.66
1.1
1.1
—
—
—
0
0
265
2029
1.74
7.50
6.2
6.1
0.58
0.59
e9/l
0.02
247
1726
268
2062
1.73
7.42
6.2
6.1
1.84
1.89
e9/l
0.27
250
1803
142
916
1.80
7.32
3.9
4.0
1.02
1.02
kg/l
1.05
114
607
265
2037
1.73
7.32
6.2
6.1
0.04
0.04
e9/l
0.61
248
1733
94
534
1.96
7.19
1.3
1.3
390.00
566.18
titre
0.76
16
123
143
946
1.75
6.67
3.7
3.7
—
0.33
—
0
9
201
1473
1.66
6.33
2.9
3.5
—
0.71
—
0
7
70
378
2.01
6.14
5.6
7.2
1.22
1.33
mmol/l
0.43
70
372
147
1006
1.68
5.95
4.0
4.1
93.42
90.74
%
0.60
140
987
15
26
5.93
5.88
1.1
1.1
—
—
—
0
0
80
460
1.90
5.84
5.6
8.1
1.55
1.02
mmol/l
0.58
63
382
95
579
1.81
5.77
2.2
2.4
23.85
23.30
%
0.14
85
540
364
3153
1.79
5.66
28.5
21.0
331.45
331.97
g/l
0.53
364
3135
355
3060
1.74
5.53
9.5
8.5
79.62
79.57
u/l
0.01
344
2900
147
1029
1.63
5.36
2.2
2.1
2.60
2.79
mg/l
0.45
135
885
89
545
1.79
5.30
1.2
1.2
—
—
—
0
0
229
1790
1.56
5.19
2.8
2.7
—
—
estimate
—
0
0
125
1737
0.61
5.08
1.9
1.9
1.43
1.34
mmol/l
0.60
104
1445
115
766
1.67
5.06
3.4
4.1
488.36
343.76
ng/l
0.27
85
606
77
462
1.80
4.89
5.7
8.1
7.41
7.41
ph
0.06
56
266
103
672
1.69
4.88
2.5
2.4
13.91
13.28
umol/l
0.34
93
622
278
2291
1.55
4.83
8.8
10.2
4.47
4.05
e9/l
0.35
260
1983
177
1323
1.55
4.79
5.9
5.9
—
—
—
0
0
154
1116
1.58
4.77
4.5
4.3
—
—
—
0
0
412
3763
2.05
4.71
23.5
16.0
23.29
24.89
mg/l
0.41
366
3088
29
122
2.47
4.66
1.2
1.3
—
—
—
0
0
263
2154
1.53
4.61
7.2
7.1
11.73
11.72
umol/l
0.00
253
2058
97
635
1.67
4.52
2.4
2.4
2.31
2.31
g/l
0.04
89
587
302
2556
1.54
4.48
5.1
4.5
95.20
951.55
e6/l
—
5
51
171
1286
1.53
4.42
3.6
3.1
2045.06
1130.95
ng/l
0.48
149
1111
49
264
1.96
4.33
2.2
2.6
—
—
—
0
0
49
264
1.96
4.33
2.9
3.3
7.42
7.42
ph
0.10
44
218
225
1805
1.49
4.21
2.3
2.5
78.37
78.08
nmol/l
0.06
209
1625
10
17
5.99
4.15
1.6
1.5
—
—
—
0
0
160
1207
1.50
4.00
1.8
1.7
22.24
20.26
nmol/l
0.93
140
1016
62
371
1.78
3.97
2.2
2.5
0.58
0.37
e6/l
0.48
62
352
18
65
2.84
3.90
1.6
1.3
—
—
—
0
0
165
1259
1.49
3.88
3.2
2.6
48.55
67.68
u/l
3.06
159
1168
223
1806
1.46
3.87
10.1
11.4
0.20
0.00
e9/l
0.49
202
1482
95
646
1.60
3.77
3.1
2.9
0.97
2.30
e6/l
2.69
75
306
163
1247
1.48
3.76
2.0
2.2
204.19
194.58
u/l
0.07
155
1182
324
2833
1.50
3.72
4.2
4.2
—
10101.80
—
0
10
12
338
0.34
3.71
1.2
1.5
—
—
—
0
0
119
1576
0.67
3.49
2.8
3.3
—
—
—
0
0
170
1329
1.45
3.45
3.5
3.2
50.71
59.23
e6/l
0.13
158
1012
136
1026
1.47
3.30
1.4
1.3
—
—
—
0
0
29
144
2.08
3.23
1.1
1.3
—
18.56
—
0
5
388
3574
1.60
3.07
5.9
5.3
1.82
1.95
mu/l
1.54
368
3285
198
1617
1.40
3.06
2.1
2.1
—
—
—
0
0
217
1806
1.39
2.97
3.4
2.8
108.69
133.42
ug/l
1.19
208
1677
14
52
2.75
2.91
1.1
1.2
—
116.66
—
0
5
186
1513
1.39
2.90
3.6
3.9
57.61
86.29
e6/l
0.57
164
1066
144
1125
1.41
2.84
3.2
3.1
0.22
0.50
e6/l
2.14
132
807
132
1016
1.42
2.83
2.0
2.7
344.22
343.35
umol/l
0.03
121
889
8
18
4.50
2.80
1.0
2.3
40.40
41.91
g/l
—
8
18
415
3905
1.75
2.80
17.8
14.4
—
—
—
0
0
154
1220
1.40
2.79
2.9
3.0
—
—
—
0
0
114
856
1.44
2.79
1.2
1.3
0.59
2.21
u/ml
2.23
14
242
120
913
1.43
2.73
2.6
2.7
5.67
5.26
e6/l
0.11
115
844
215
1822
1.34
2.48
2.1
2.1
94.64
96.41
pmol/l
0.23
115
963
32
183
1.81
2.43
3.4
3.2
—
—
—
0
0
5
8
6.30
2.37
1.0
1.3
26.20
27.50
s
—
5
8
56
380
1.54
2.25
2.9
2.3
36.90
36.47
u/l
0.03
42
315
8
197
0.40
2.23
1.6
3.2
25.39
25.34
mmol/l
—
8
190
5
9
5.60
2.22
1.0
1.0
—
—
—
0
0
63
443
1.49
2.15
1.6
1.6
—
—
—
0
0
29
168
1.78
2.13
1.7
2.1
0.55
2.87
ug/l
0.81
24
154
330
3015
1.35
2.11
5.2
4.3
14.76
14.84
pmol/l
0.26
315
2748
9
32
2.85
2.01
1.7
1.0
—
—
—
0
0
32
195
1.69
1.99
2.1
2.3
—
—
—
0
0
13
264
0.48
1.92
2.2
2.9
126.85
128.81
g/l
0.09
13
255
27
160
1.73
1.86
1.4
1.5
0.38
0.35
mg/l
0.08
15
69
240
2121
1.28
1.85
4.0
3.8
0.00
7.71
estimate
0.80
34
454
111
886
1.33
1.84
1.8
1.7
1.29
1.35
mg/l
0.05
87
719
96
1202
0.74
1.80
4.7
4.0
0.00
0.00
estimate
0.50
29
413
421
4040
1.60
1.79
14.3
12.4
25.70
25.29
u/l
0.21
414
3935
84
646
1.37
1.77
2.0
1.8
30.05
29.26
s
0.87
84
628
14
68
2.09
1.72
1.5
1.4
—
—
—
0
0
16
82
1.99
1.71
2.6
4.7
—
—
—
0
0
186
1605
1.27
1.70
3.8
3.8
0.00
0.02
estimate
1.41
30
363
237
2107
1.26
1.68
4.0
3.8
0.00
0.00
estimate
-0.00
34
444
5
14
3.60
1.62
1.0
1.1
143.60
114.22
iu/ml
—
5
14
205
1811
1.24
1.48
5.0
5.1
34.90
35.66
g/l
1.02
197
1702
396
3780
1.38
1.47
5.3
5.3
5.97
5.97
mmol/l
0.03
375
3474
21
337
0.60
1.46
5.7
3.6
1.23
1.23
mmol/l
0.11
16
290
13
66
2.00
1.44
1.5
1.8
—
—
—
0
0
16
89
1.83
1.39
1.1
1.3
—
—
—
0
0
93
754
1.29
1.38
1.4
1.5
2.70
2.58
g/l
0.12
44
461
6
23
2.63
1.37
1.0
1.2
—
—
—
0
0
238
2151
1.22
1.35
4.0
3.8
0.00
0.73
estimate
0.53
32
428
9
43
2.11
1.31
1.1
1.1
—
—
—
0
0
6
24
2.52
1.31
1.7
1.5
59.83
99.69
ng/l
—
6
24
13
69
1.91
1.30
1.1
1.0
—
—
—
0
0
19
299
0.62
1.24
1.4
1.8
3.28
3.59
mmol/l
0.76
13
227
5
19
2.65
1.22
1.0
1.3
98.63
190.61
mmol/24h
—
5
19
16
94
1.73
1.19
1.8
1.2
452.25
489.25
mg/l
0.17
16
89
38
275
1.42
1.18
1.1
1.2
—
—
—
0
0
20
126
1.61
1.16
1.2
1.1
—
—
—
0
0
13
72
1.83
1.16
1.5
1.1
—
—
—
0
0
12
65
1.87
1.14
1.1
1.0
—
—
—
0
0
70
563
1.29
1.11
2.7
1.9
—
—
—
0
0
55
429
1.32
1.09
2.6
3.3
7.40
7.38
ph
1.29
44
246
5
21
2.40
1.09
1.8
2.3
2.32
2.04
ug/l
—
5
16
146
1280
1.21
1.08
2.4
2.4
—
—
—
0
0
58
458
1.31
1.06
3.3
5.0
4.40
17.95
ug/l
0.81
46
378
99
1161
0.81
1.06
3.5
3.3
0.00
0.07
estimate
0.52
30
348
12
67
1.81
1.05
1.2
1.4
—
—
—
0
0
16
98
1.66
1.04
2.4
1.8
—
—
—
0
0
10
54
1.87
0.97
1.7
3.3
—
—
—
0
0
9
50
1.82
0.97
1.2
1.5
—
—
—
0
0
186
1681
1.18
0.97
3.3
3.4
6.04
6.18
ph
1.19
130
952
144
1274
1.19
0.95
4.8
5.5
1.71
2.57
ug/l
1.92
133
1143
6
27
2.24
0.93
1.0
1.3
—
—
—
0
0
32
236
1.38
0.92
1.1
1.2
214.69
132.40
u/ml
0.30
12
106
27
367
0.72
0.89
3.5
4.5
0.14
0.65
%
—
7
116
71
840
0.82
0.83
1.7
1.7
417.48
31268443.99
pmol/l
0.94
58
694
8
46
1.75
0.83
1.5
1.3
—
—
—
0
0
75
881
0.82
0.81
2.6
2.9
2.45
2.46
mmol/l
0.04
69
801
43
342
1.28
0.78
4.8
7.2
10.88
10.29
mmol/l
0.20
43
324
30
390
0.75
0.76
3.4
4.6
0.50
0.98
%
—
8
129
0
28
0.00
0.76
0.0
17.6
—
801.32
—
0
28
20
141
1.44
0.76
3.6
3.9
62.42
91.96
mg/l
0.27
20
124
20
141
1.44
0.76
3.6
3.9
28.89
67.88
mg/l
0.99
20
124
9
53
1.71
0.76
1.2
1.3
—
—
—
0
0
6
108
0.55
0.73
1.0
1.1
—
0.76
—
0
20
11
68
1.63
0.72
1.1
1.1
—
—
—
0
0
7
40
1.76
0.71
2.1
2.1
—
—
—
0
0
9
146
0.61
0.70
1.2
1.6
—
10.79
—
0
29
5
93
0.53
0.67
1.6
3.3
6.32
7.99
mmol/l
—
5
88
7
43
1.64
0.67
1.6
1.4
—
—
—
0
0
16
111
1.46
0.66
1.7
1.8
6.68
5.07
iu/l
—
6
47
56
470
1.22
0.66
1.9
2.8
2.13
1.83
%
0.91
49
421
5
28
1.79
0.66
1.2
1.7
42.90
39.24
%
—
5
28
44
361
1.24
0.64
2.0
3.0
71.55
71.00
e9/l
0.04
34
259
16
112
1.44
0.64
1.6
2.5
14.51
12.50
mg/l
0.76
16
104
31
388
0.78
0.62
1.5
1.5
—
—
—
0
0
29
366
0.78
0.62
3.4
4.7
0.00
0.12
%
—
7
105
5
30
1.67
0.61
1.2
1.1
—
—
—
0
0
55
466
1.21
0.60
1.4
1.7
—
—
—
0
0
23
297
0.76
0.58
1.1
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
2.5
—
493.50
—
0
16
6
35
1.72
0.58
1.7
1.7
—
—
—
0
0
6
37
1.63
0.55
1.0
1.4
—
—
—
0
0
6
37
1.63
0.55
2.0
1.1
—
—
—
0
0
13
182
0.71
0.55
2.5
1.8
—
—
—
0
0
27
215
1.27
0.52
1.1
1.2
—
—
—
0
0
62
540
1.17
0.51
1.2
1.3
—
—
—
0
0
154
1430
1.12
0.50
3.4
4.0
6.71
7.62
mg/mmol
0.14
98
875
59
674
0.86
0.49
1.8
1.7
1210.18
1234.86
nmol/l
0.09
45
504
7
47
1.50
0.47
1.4
1.4
—
—
—
0
0
8
120
0.66
0.46
1.0
1.1
0.84
0.94
g/l
—
8
120
68
762
0.87
0.45
2.3
3.2
0.65
0.74
ug/l
0.80
43
514
20
158
1.28
0.42
2.2
3.0
—
—
—
0
0
5
32
1.57
0.42
2.4
2.2
—
22.26
—
0
5
5
32
1.57
0.42
1.0
1.3
—
—
—
0
0
5
33
1.52
0.41
1.0
1.8
1349.40
1264.64
e6/l
—
5
28
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
378
3701
1.13
0.41
6.1
6.5
39.08
39.47
mmol/mol
0.47
359
3483
8
60
1.34
0.40
1.5
1.8
1.63
1.44
mmol/l
—
8
60
0
18
0.00
0.40
0.0
13.3
—
0.70
—
0
18
54
477
1.15
0.39
1.3
1.4
—
—
—
0
0
9
66
1.37
0.38
1.2
1.3
—
—
—
0
0
8
115
0.69
0.37
2.0
3.1
1.21
1.66
mmol/l
—
8
110
9
69
1.31
0.37
1.2
1.3
—
—
—
0
0
62
556
1.13
0.37
3.8
5.3
1.06
1.03
mmol/l
0.23
62
509
8
116
0.68
0.37
1.0
1.1
1.76
1.59
g/l
—
8
116
5
37
1.36
0.37
2.4
2.2
—
—
—
0
0
5
37
1.36
0.37
2.8
1.8
—
—
—
0
0
42
366
1.16
0.37
2.3
2.6
4.16
4.34
kpa
0.32
42
352
9
71
1.27
0.36
1.2
1.3
—
—
—
0
0
9
71
1.27
0.36
1.2
1.3
—
—
—
0
0
5
77
0.65
0.36
2.6
3.4
60.60
58.50
%
—
5
77
9
126
0.71
0.35
2.1
9.3
—
—
—
0
0
14
178
0.78
0.35
1.3
1.2
—
—
—
0
0
14
109
1.29
0.34
1.5
1.4
291.57
309.11
ug/g
—
7
58
6
47
1.28
0.32
1.2
1.3
—
—
—
0
0
45
504
0.88
0.31
1.2
1.3
—
—
—
0
0
7
52
1.35
0.31
1.6
1.8
—
—
—
0
0
266
2581
1.07
0.30
3.5
3.3
55.44
50.67
u/l
0.42
255
2425
147
1396
1.08
0.30
3.0
3.3
42.45
45.76
mg/l
0.08
102
887
28
243
1.16
0.27
1.1
1.4
—
—
—
0
0
150
1431
1.07
0.27
3.0
3.3
6.97
7.39
mmol/l
0.62
142
1205
26
299
0.86
0.26
4.6
3.7
—
—
—
0
0
10
77
1.31
0.26
1.1
1.2
54.30
58.93
mmol/l
—
10
67
5
72
0.69
0.26
1.0
1.2
—
—
—
0
0
29
254
1.15
0.26
1.2
1.2
—
—
—
0
0
9
75
1.20
0.25
1.6
2.1
4.71
4.65
mmol/24h
—
9
69
85
905
0.93
0.24
3.5
4.9
—
—
—
0
0
6
85
0.70
0.24
6.0
3.0
12.53
7.94
pmol/l
—
6
85
6
85
0.70
0.24
3.2
3.7
12.25
28.47
mg/l
—
6
59
5
39
1.29
0.23
1.0
1.2
—
—
—
0
0
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
395
3905
1.09
0.22
5.8
6.1
2.65
2.72
mmol/l
0.85
377
3642
35
387
0.90
0.21
1.2
1.4
—
—
—
0
0
5
42
1.19
0.21
1.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
9.15
—
0
11
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
0.57
—
0
5
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
14
117
1.20
0.20
1.1
1.2
—
—
—
0
0
10
123
0.81
0.20
3.1
2.8
1.72
1.48
mg/l
—
10
105
389
3846
1.08
0.20
5.2
5.3
4.54
4.67
mmol/l
1.92
371
3595
47
433
1.10
0.20
2.6
3.3
5.71
5.80
kpa
0.23
47
419
6
51
1.18
0.19
4.0
2.1
—
—
—
0
0
17
147
1.16
0.18
2.3
2.0
180.76
488.63
ug/l
0.86
17
141
7
59
1.19
0.18
1.3
1.5
—
—
—
0
0
7
59
1.19
0.18
1.3
1.5
—
—
—
0
0
7
59
1.19
0.18
1.3
1.5
—
—
—
0
0
7
59
1.19
0.18
1.3
1.5
—
—
—
0
0
43
398
1.09
0.17
2.0
2.3
0.20
0.22
g/l
0.64
36
373
15
173
0.86
0.17
1.1
1.1
—
82.29
—
0
7
8
70
1.15
0.16
1.3
1.3
—
—
—
0
0
33
359
0.91
0.16
2.5
4.3
7.38
7.36
ph
1.03
22
255
16
180
0.88
0.13
1.5
1.6
—
—
—
0
0
11
127
0.86
0.12
1.8
3.7
1.03
1.35
mmol/l
1.63
11
122
61
582
1.06
0.12
6.4
6.7
105.31
103.92
mmol/l
1.91
61
582
5
46
1.09
0.09
4.8
3.3
1.62
6.94
nmol/l
—
5
46
6
58
1.03
0.08
1.5
2.3
33.33
32.14
pg
—
6
58
10
113
0.88
0.08
1.1
1.1
—
—
—
0
0
5
62
0.80
0.08
2.4
7.0
312.20
350.79
umol/l
—
5
56
42
401
1.05
0.08
1.4
1.5
—
—
—
0
0
17
184
0.92
0.07
1.1
1.1
—
—
—
0
0
371
3688
1.03
0.07
4.4
4.4
1.37
1.29
mmol/l
1.40
351
3394
10
112
0.89
0.07
1.2
1.2
—
81.00
—
0
10
7
81
0.86
0.07
1.3
1.5
—
—
—
0
0
46
443
1.04
0.06
1.2
1.5
—
—
—
0
0
384
3826
1.02
0.04
4.9
5.2
1.43
1.49
mmol/l
2.72
365
3552
34
349
0.97
0.02
8.2
8.4
—
—
—
0
0
38
374
1.02
0.00
1.2
1.6
—
—
—
0
0
76
763
1.00
0.00
2.6
2.9
542.81
530.54
mosm/kgh2o
0.15
70
672
46
465
0.99
0.00
2.0
2.6
115.66
125.29
ug/g
0.12
40
377
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
2.2
3.5
4.09
4.58
e9/l
—
5
57
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
4.7
—
7.11
—
0
7
0
7
0.00
0.00
0.0
2.3
—
11006.14
—
0
7
8
83
0.96
-0.00
1.0
1.2
20.30
19.60
u/l
—
8
69
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
0.52
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
96
0.94
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
18.42
—
0
6
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
21
210
1.00
-0.00
2.2
2.2
0.00
0.02
estimate
—
7
66
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
17.90
—
0
6
146
1460
1.00
-0.00
2.8
3.7
2.36
2.36
mmol/l
0.20
138
1324
0
5
0.00
-0.00
0.0
1.2
—
43.00
—
0
5
8
87
0.92
-0.00
3.8
3.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.56
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint G6_LSROOT and mortality.

Females

Parameter HR [95% CI] p-value
G6_LSROOT 1.109 [0.93, 1.32] 0.251
Birth year 0.998 [0.99, 1.01] 0.698

During the follow-up period (1.1.1998 — 31.12.2019), 198 out of 1477 females with G6_LSROOT died.

Males

Parameter HR [95% CI] p-value
G6_LSROOT 1.121 [0.94, 1.34] 0.205
Birth year 0.989 [0.98, 1.0] 0.017

During the follow-up period (1.1.1998 — 31.12.2019), 241 out of 1304 males with G6_LSROOT died.

Mortality risk

Mortality risk for people of age

years, who have G6_LSROOT.

N-year risk Females Males
1 0.112% 0.173%
5 0.749% 1.307%
10 1.701% 3.452%
15 3.364% 6.466%
20 6.176% 10.951%

Relationships between endpoints

↥

Index endpoint: G6_LSROOT – Lumbosacral root disorders, not elsewhere classified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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