Henoch-Schoenlein purpura: A systemic, usually self-limited immune complex vasculitis, characterized by immunoglobulin A deposition in the small vessels and kidneys. It is manifested with small hemorrhages in the skin, gastrointestinal symptoms, arthritis, and nephropathy.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1326 |
4. Check minimum number of eventsNone |
1326 |
5. Include endpointsNone |
1326 |
6. Filter based on genotype QC (FinnGen only) |
1181 |
Control definitions (FinnGen only)
- Control exclude
- D3_COAGDEF_PURPUR_HAEMORRHAGIC
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D69
- Name in latin
- Purpura allergica
Similar endpoints
↥List of similar endpoints to
Allergic purpura
based on the number of shared cases.
Similar with more cases:
- Purpura and other haemorrhagic conditions
- Coagulation defects, purpura and other haemorrhagic conditions
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 11658 | 5675 | 5938 |
| Only index persons | 10225 | 5070 | 5155 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.16 | 0.17 |
| Only index persons | 0.19 | 0.19 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 19.15 | 23.45 | 14.73 |
| Only index persons | 18.96 | 23.33 | 14.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1181 | 690 | 491 |
| Unadjusted period prevalence (%) | 0.24 | 0.24 | 0.23 |
| Median age at first event (years) | 40.87 | 35.91 | 47.83 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1232
- Matched controls
- 12320
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D69.0
ICD-10 Finland
Allergic purpura
9067.6
307.7
917
*
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
124.1
262.4
133
12
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.6
185.6
310
522
28700
ICD-8 Finland
Purpura and other haemorrhagic conditions, Allergic purpura
+∞
175.3
164
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
46.2
165.5
98
23
N08.2*D69.0
ICD-10 Finland
Glomerular disorders in Henoch(-Schönlein) purpura
+∞
148.0
139
*
2870A
ICD-9 Finland
Purpura and other haemorrhagic conditions, Allergic purpura[PURPURA HENOCH-SCHÖNLEIN]
+∞
102.6
97
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
14.9
79.8
72
51
H02AB06
ATC
prednisolone; systemic
3.0
75.2
739
4127
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
28.2
60.4
41
15
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
130.4
58.4
62
5
J04BA02
ATC
dapsone; oral
22.3
55.3
41
19
L95.8
ICD-10 Finland
Other vasculitis limited to skin
72.3
54.7
62
9
M36.4*D69.0
ICD-10 Finland
Arthropathy in Henoch(-Schönlein) purpura
+∞
52.5
50
*
D69.2
ICD-10 Finland
Other nonthrombocytopenic purpura
180.8
50.3
52
*
L04AX01
ATC
azathioprine; systemic
4.9
47.5
109
237
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
59.6
39.5
46
8
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
38.4
229
935
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
35.5
422
2348
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
4.0
34.6
102
269
D07AC01
ATC
betamethasone; topical
2.1
34.5
504
3033
L04AA01
ATC
[U] ciclosporin
10.0
34.0
39
40
N18.8
ICD-10 Finland
Other chronic renal failure
7.2
33.2
50
72
C03CA01
ATC
furosemide; systemic
2.2
33.2
361
1930
L04AA06
ATC
mycophenolic acid; systemic
6.2
31.3
54
90
D69
ICD-10 Finland
Purpura and other haemorrhagic conditions
84.8
29.9
33
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
29.1
589
3916
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.4
28.3
57
110
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
8.1
28.2
38
48
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
48.4
27.5
33
7
R23.3
ICD-10 Finland
Spontaneous ecchymoses
5.6
26.8
52
97
TK800
NOMESCO Finland
Hemodialysis
5.9
26.5
48
84
Z94.0
ICD-10 Finland
Kidney transplant status
7.5
26.4
38
52
Z49.1
ICD-10 Finland
Extracorporeal dialysis
7.9
26.0
36
47
H02AB07
ATC
prednisone; oral
2.5
25.8
191
856
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.4
25.0
50
96
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
255.1
24.8
25
*
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
132.7
24.7
26
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.5
24.4
86
256
127
Kela drug reimbursment
Transplant complication
6.1
24.4
43
73
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.5
24.4
166
715
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.3
23.8
48
93
E0000UV, ,
ATC
1.8
23.6
553
3779
H02AB04
ATC
methylprednisolone; systemic
2.3
23.0
198
947
A46
ICD-10 Finland
Erysipelas
2.3
22.4
192
915
L04AD01
ATC
ciclosporin; systemic
5.5
22.2
43
80
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
22.0
160
710
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
21.9
298
1697
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
21.1
147
638
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.9
20.9
101
364
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.0
20.7
94
327
L95.0
ICD-10 Finland
Livedoid vasculitis
111.9
20.6
22
*
TQW80
NOMESCO Finland
Local dermatologic skincare
4.5
20.5
51
118
L81.7
ICD-10 Finland
Pigmented purpuric dermatosis
26.0
20.5
28
11
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
20.4
207
1055
A12AA04
ATC
calcium carbonate; oral
6.0
20.2
36
62
A02BC02
ATC
pantoprazole; systemic
1.8
20.1
809
6365
D07AB08
ATC
desonide; topical
2.3
19.8
158
729
A11CC03
ATC
alfacalcidol; systemic
4.4
18.4
47
111
M04AA01
ATC
allopurinol; systemic
2.3
18.0
146
677
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.9
17.0
80
284
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
16.8
331
2102
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
6.9
16.2
25
37
137
Kela drug reimbursment
Uraemia requiring dialysis
7.2
16.1
24
34
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.5
16.0
55
161
A41.9
ICD-10 Finland
Sepsis, unspecified
3.5
15.6
54
159
V03AE01
ATC
polystyrene sulfonate; oral
6.0
15.3
27
46
N02AX02
ATC
tramadol; systemic, rectal
1.6
15.2
487
3509
R31
ICD-10 Finland
Unspecified haematuria
2.3
15.1
125
584
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
15.1
261
1587
J01MA12
ATC
levofloxacin; systemic
1.9
15.0
212
1208
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.7
14.9
82
317
L04AD02
ATC
tacrolimus; systemic
5.6
14.3
27
49
E000001, ,
ATC
1.8
14.2
252
1542
A02BC01
ATC
omeprazole; systemic
1.7
13.8
304
1977
E000006, ,
ATC
2.5
13.7
92
392
L04AX03
ATC
methotrexate; systemic
2.2
13.6
128
630
D09AB01
ATC
zinc bandage without supplements; topical
4.7
13.6
31
67
R50.9
ICD-10 Finland
Fever, unspecified
1.9
13.5
204
1187
B03XA02
ATC
darbepoetin alfa; parenteral
4.3
13.5
35
84
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.4
13.5
95
414
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
13.4
257
1605
M10.9
ICD-10 Finland
Gout, unspecified
2.6
13.4
81
328
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.8
13.4
69
258
D64.9
ICD-10 Finland
Anaemia, unspecified
2.2
13.3
116
553
205
Kela drug reimbursment
Chronic hypertension
1.8
13.3
247
1529
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.0
13.2
37
94
R80
ICD-10 Finland
Isolated proteinuria
10.2
13.0
25
25
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
12.9
454
3314
D07AC13
ATC
mometasone; topical
1.6
12.9
339
2305
J01MA02
ATC
ciprofloxacin; systemic
1.6
12.8
419
3006
ZX120
NOMESCO Finland
Intravenous
2.2
12.8
116
563
M30.0
ICD-10 Finland
Polyarteritis nodosa
47.1
11.9
14
*
D07AD01
ATC
clobetasol; topical
1.8
11.9
191
1130
R06AE07
ATC
cetirizine; oral
1.5
11.8
533
4090
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
9.0
11.8
24
27
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.5
11.7
28
63
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.6
11.7
66
259
P01BA02
ATC
hydroxychloroquine; oral
2.2
11.4
99
471
B01AA03
ATC
warfarin; systemic
1.8
11.2
176
1033
L01BA01
ATC
methotrexate; systemic
3.0
11.1
48
163
N18.0
ICD-10 Finland
End-stage renal disease
5.8
11.0
20
35
Z3231
NOMESCO Finland
Registered nurse
1.6
10.9
314
2169
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
8.9
10.8
22
25
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
28.3
10.7
14
5
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.7
10.7
33
90
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
10.7
262
1738
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.6
10.7
20
36
M05BA04
ATC
alendronic acid; oral
2.2
10.7
90
423
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
10.7
289
1965
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
21.7
10.7
15
7
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
10.7
117
609
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.9
10.6
50
178
J01FF01
ATC
clindamycin; systemic
1.6
10.6
307
2122
M36.4
ICD-10 Finland
Arthropathy in hypersensitivity reactions classified elsewhere
+∞
10.4
10
*
J01DB01
ATC
cefalexin; oral
1.6
10.3
995
8868
C02AC05
ATC
moxonidine; oral
2.7
10.3
54
204
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
4.5
10.3
25
57
C03DA01
ATC
spironolactone; oral
1.9
10.3
128
697
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.9
10.3
49
176
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.6
10.2
33
93
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
10.2
192
1186
R06AX27
ATC
desloratadine; oral
1.5
10.2
372
2705
B03XA01
ATC
erythropoietin; parenteral
7.5
10.2
23
31
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
10.2
113
591
J01FA06
ATC
roxithromycin; oral
1.5
10.1
435
3276
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.4
10.1
70
303
D68.8
ICD-10 Finland
Other specified coagulation defects
14.7
10.0
16
11
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
9.8
140
796
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.0
9.8
27
68
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
9.7
275
1887
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
3.5
9.7
32
92
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.3
9.6
70
310
C08CA01
ATC
amlodipine; oral
1.5
9.6
368
2700
J01CA04
ATC
amoxicillin; systemic
1.6
9.5
1001
8983
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
9.5
317
2255
D68.9
ICD-10 Finland
Coagulation defect, unspecified
100.8
9.4
10
*
D68.0
ICD-10 Finland
Von Willebrand disease
100.8
9.4
10
*
Z3226
NOMESCO Finland
Physiotherapist
1.7
9.4
207
1333
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
17.7
9.4
14
8
C09AA02
ATC
enalapril; systemic
1.7
9.4
181
1125
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
9.4
178
1102
M13.9
ICD-10 Finland
Arthritis, unspecified
2.1
9.4
92
460
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
9.3
220
1442
J01AA02
ATC
doxycycline; systemic
1.5
9.3
862
7501
XW000
NOMESCO Finland
Bone marrow biopsy
2.9
9.3
43
152
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
4.6
9.1
21
46
R60.0
ICD-10 Finland
Localized oedema
1.8
9.1
134
771
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
37.0
9.0
11
*
Z2221
NOMESCO Finland
Medical doctor
1.5
9.0
313
2244
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.4
8.9
31
92
D07AA02
ATC
hydrocortisone; topical
1.7
8.9
180
1132
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.4
8.7
60
259
J01DA01
ATC
[U] cefalexin
1.4
8.7
692
5809
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
8.7
396
2997
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
50.4
8.7
10
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.9
8.7
112
617
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
8.6
336
2466
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
8.6
108
590
C08CA02
ATC
felodipine; oral
2.0
8.5
90
463
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
6.5
8.5
21
33
WX002
NOMESCO Finland
Sedation and analgesia
1.6
8.4
197
1289
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
+∞
8.3
8
*
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
8.3
160
993
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
8.3
85
432
V03AE02
ATC
sevelamer; oral
9.5
8.3
16
17
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
8.2
83
420
S97
ICPC
Chronic ulcer skin
2.2
8.2
72
345
H02AB09
ATC
hydrocortisone; systemic
3.1
8.2
34
113
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
8.2
132
780
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
11.8
8.1
14
12
WX892
NOMESCO Finland
Monitored bed care
2.0
8.0
87
452
M25.5
ICD-10 Finland
Pain in joint
1.4
7.9
385
2945
SPAT1172
SPAT
Guidance concerning hydration
3.4
7.8
27
80
C09CA01
ATC
losartan; oral
1.5
7.6
243
1703
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
7.6
623
5208
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
7.6
98
540
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
7.6
165
1057
L04AA13
ATC
[U] leflunomide
3.1
7.6
30
97
E000002, ,
ATC
1.7
7.6
133
805
212
Kela drug reimbursment
Gout
3.8
7.5
22
58
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
7.5
141
870
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
7.5
202
1365
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
7.4
83
436
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
7.4
182
1203
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
7.3
107
613
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.8
7.3
116
681
C07AB02
ATC
metoprolol; systemic
1.6
7.3
183
1214
2870X
ICD-9 Finland
Purpura and other haemorrhagic conditions, Allergic purpura[PURPURA ALLERGICA NUD]
+∞
7.3
7
*
D69.1
ICD-10 Finland
Qualitative platelet defects
+∞
7.3
7
*
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
3.5
7.3
24
69
B05DA
ATC
Isotonic solutions
6.3
7.2
18
29
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
7.2
93
512
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
7.2
113
661
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
15.8
7.2
11
7
R60.9
ICD-10 Finland
Oedema, unspecified
2.2
7.2
62
295
XQ800
NOMESCO Finland
Prick test
1.9
7.2
91
498
J46
ICD-10 Finland
Status asthmaticus
2.7
7.2
38
145
L30.3
ICD-10 Finland
Infective dermatitis
2.5
7.2
44
181
C07AG02
ATC
carvedilol; oral
2.2
7.1
60
283
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
7.1
110
641
Z49.2
ICD-10 Finland
Other dialysis
6.6
7.1
17
26
Z49.0
ICD-10 Finland
Preparatory care for dialysis
5.7
7.1
19
34
B01AB04
ATC
dalteparin; parenteral
2.3
7.1
54
245
C07AB07
ATC
bisoprolol; oral
1.4
7.0
458
3670
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
7.0
570
4736
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
7.0
135
839
R06.0
ICD-10 Finland
Dyspnoea
1.5
6.9
287
2120
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.2
6.9
27
87
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
3.4
6.8
24
72
R4110
NOMESCO Finland
Physiotherapy
1.5
6.8
294
2188
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
6.1
6.8
17
28
N03AX16
ATC
[U] pregabalin
1.5
6.7
229
1627
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
6.7
85
467
B01AB05
ATC
enoxaparin; parenteral
1.4
6.7
304
2284
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
6.7
137
865
L84
ICD-10 Finland
Corns and callosities
2.4
6.7
42
175
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
7.9
6.6
14
18
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
6.6
293
2190
L01AA01
ATC
cyclophosphamide; systemic
8.7
6.6
13
15
L88
ICPC
Rheumatoid/seropositive arthritis
2.3
6.5
46
202
ZXE00
NOMESCO Finland
One hour or less
1.4
6.5
415
3304
UJF32
NOMESCO Finland
Coloscopy
1.5
6.5
248
1800
A07AA02
ATC
nystatin; oral
2.1
6.5
58
281
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
6.5
464
3765
L52
ICD-10 Finland
Erythema nodosum
5.7
6.5
17
30
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.0
6.5
28
96
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
70.2
6.4
7
*
D02AE01
ATC
carbamide; topical
2.0
6.4
72
379
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.7
6.4
34
130
TK820
NOMESCO Finland
Peritoneal dialysis
7.4
6.4
14
19
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
6.4
422
3379
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.3
281
2099
J01MA14
ATC
moxifloxacin; systemic
1.8
6.3
90
513
126
Kela drug reimbursment
Chronic coagulation defects
+∞
6.3
6
*
D69.4
ICD-10 Finland
Other primary thrombocytopenia
+∞
6.3
6
*
UKC02
NOMESCO Finland
Cystoscopy
1.6
6.2
144
936
58399
ICD-8 Finland
Nephritis, unqualified
26.8
6.2
8
*
XX1XW
NOMESCO Finland
Extensive written report from radiologist
3.1
6.2
25
82
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
6.3
6.2
15
24
B05DB
ATC
Hypertonic solutions
6.3
6.2
15
24
Z2446
NOMESCO Finland
Social worker
1.8
6.1
84
473
C08CA13
ATC
lercanidipine; oral
1.6
6.1
129
821
M79.6
ICD-10 Finland
Pain in limb
1.4
6.1
485
3991
D02AX
ATC
Other emollients and protectives
2.4
6.1
38
158
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
6.0
73
395
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
258
412
7.66
160.98
1.9
1.5
15.58
10.09
iu/ml
—
9
15
194
273
8.25
134.44
2.0
1.3
9.20
6.35
iu/ml
—
8
6
198
336
6.83
115.11
1.7
1.6
0.24
0.24
g/l
0.15
186
324
198
349
6.57
110.75
1.7
1.6
1.22
1.20
g/l
0.29
186
334
114
179
6.92
70.51
1.5
1.3
252.86
182.00
titre
—
14
10
176
453
4.37
62.65
1.9
1.9
9.20
7.41
iu/ml
0.24
39
110
238
866
3.17
50.00
11.1
7.5
9.69
9.01
mmol/l
0.72
226
832
297
1336
2.61
41.33
10.8
5.9
1.09
1.05
mmol/l
1.25
280
1242
145
440
3.60
40.37
1.3
1.2
2.29
1.31
u/ml
0.18
12
24
187
740
2.80
32.98
2.0
2.7
66.78
66.87
g/l
0.05
179
685
832
6122
2.11
32.01
12.4
9.3
4.40
4.07
e9/l
3.54
754
5341
520
3330
1.97
28.54
6.0
3.4
39.04
78.13
e6/l
1.06
414
2517
177
748
2.60
27.17
6.6
4.3
119.21
84.69
ng/l
2.67
164
665
165
682
2.64
26.47
1.8
1.8
1.08
1.43
g/l
1.67
148
634
100
315
3.37
26.05
1.3
1.2
1.59
2.64
u/ml
—
10
32
191
860
2.44
25.56
3.4
2.8
10.79
10.66
g/l
0.16
176
795
99
316
3.32
25.25
1.3
1.2
4.42
8.77
u/ml
0.53
12
49
111
383
3.09
24.87
1.7
2.2
1.63
1.48
g/l
0.75
96
341
472
3031
1.90
24.81
6.7
4.3
19.34
8.94
mg/mmol
2.93
364
1929
464
2974
1.90
24.45
5.6
3.6
116.89
52.39
mg/l
3.95
356
1936
50
98
5.28
24.44
1.3
1.1
73.33
114.00
titre
—
9
15
271
1445
2.12
24.10
4.2
2.6
21.40
23.52
%
1.95
258
1355
620
4368
1.84
24.10
8.3
5.0
35.38
36.30
g/l
3.76
590
4113
305
1705
2.05
23.87
4.0
2.5
12.42
13.73
umol/l
2.89
293
1592
100
333
3.18
23.78
1.3
1.2
51.14
22.11
u/ml
—
8
15
177
795
2.43
23.73
2.8
2.6
79.62
70.09
e9/l
2.08
132
583
212
1034
2.27
23.52
3.7
4.2
231.42
249.85
u/l
1.15
203
985
448
2874
1.88
23.29
5.7
3.2
0.35
0.39
e6/l
0.08
331
2081
44
84
5.40
22.14
1.1
1.1
—
—
—
0
0
45
89
5.21
21.78
1.1
1.1
—
—
—
0
0
45
89
5.21
21.78
1.1
1.1
—
—
—
0
0
616
4424
1.78
21.63
10.4
6.8
1.21
1.21
mmol/l
0.28
590
4099
368
2260
1.90
21.60
4.9
2.7
4.51
6.48
e6/l
2.30
346
2064
281
1587
2.00
21.07
4.1
2.5
2.34
2.35
g/l
0.11
265
1470
502
3435
1.78
20.47
5.9
3.5
7.79
8.00
mmol/l
0.49
457
2963
45
94
4.93
20.47
1.1
1.1
—
—
—
0
0
43
88
5.03
20.03
1.1
1.1
—
—
—
0
0
393
2527
1.82
19.58
3.4
2.7
363.75
338.37
umol/l
4.71
354
2271
297
1759
1.91
19.16
4.4
2.9
0.80
1.04
e6/l
0.78
166
890
662
4968
1.72
18.95
12.2
7.1
1.21
1.21
mmol/l
0.26
577
4330
262
1503
1.94
18.53
3.0
2.0
29.94
29.38
s
0.54
252
1455
113
463
2.59
18.28
1.9
2.3
38.76
38.80
u/l
0.01
97
417
78
264
3.09
18.03
2.1
2.7
0.00
0.00
g/l
-0.00
73
231
73
238
3.20
17.96
7.3
5.5
446.08
357.50
iu/ml
0.14
12
22
380
2481
1.77
17.64
1.6
1.5
3.06
2.31
g/l
9.71
257
1590
86
312
2.89
17.59
2.0
2.9
0.40
0.82
g/l
0.79
79
278
31
53
5.97
17.50
1.2
1.1
355.79
156.04
iu/ml
1.24
31
53
725
5654
1.69
17.31
5.9
3.7
0.00
0.00
estimate
0.50
151
1192
728
5709
1.67
16.78
5.9
3.7
16.89
4.16
estimate
0.53
154
1203
44
107
4.23
16.63
1.1
1.1
—
—
—
0
0
728
5744
1.65
16.07
5.9
3.7
0.00
0.28
estimate
0.54
150
1131
199
1088
1.99
16.01
2.5
2.1
337.68
379.48
nmol/l
2.38
182
1023
273
1659
1.83
15.90
4.3
3.5
0.80
0.82
mmol/l
3.30
258
1574
272
1661
1.82
15.56
4.9
3.0
2.80
2.42
e6/l
0.25
138
792
28
51
5.59
14.82
1.2
1.1
—
—
—
0
0
906
7648
1.70
14.62
6.9
4.2
14.25
10.84
mm/h
7.91
866
7191
918
7781
1.71
14.54
12.0
7.8
78.26
77.97
u/l
0.08
884
7412
265
1648
1.77
14.12
2.4
1.9
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
70
257
2.83
14.02
2.8
3.3
0.29
0.37
iu/ml
1.11
30
125
54
174
3.20
13.58
1.3
1.2
9.35
3.28
u/ml
0.71
20
58
823
6849
1.61
13.32
5.9
4.4
607.07
1632.12
e6/l
0.87
15
105
669
5322
1.56
13.04
7.7
6.2
10.54
11.39
umol/l
1.30
644
5091
614
4799
1.56
12.89
15.1
10.7
0.00
0.00
e9/l
0.30
506
3915
124
623
2.10
12.47
6.5
4.2
24.02
24.16
mmol/l
0.22
124
615
563
4342
1.55
12.38
18.1
12.8
1.29
1.21
inr
2.52
497
3611
349
2422
1.62
12.08
2.1
1.8
1.21
1.13
mg/l
0.20
271
1834
608
4790
1.53
11.99
3.3
2.5
75.37
75.08
nmol/l
0.09
573
4399
51
173
3.03
11.79
1.4
1.2
5.74
3.70
u/ml
0.55
23
71
150
827
1.93
11.62
4.5
2.6
0.46
0.47
e6/l
0.00
145
792
172
1000
1.84
11.30
7.0
4.0
1.45
1.70
mmol/l
0.43
150
859
70
288
2.52
11.24
1.8
2.6
10.76
11.99
mg/l
0.64
62
267
68
277
2.54
11.15
1.9
4.0
38.04
47.11
mg/l
0.34
59
233
68
277
2.54
11.15
1.9
4.0
42.37
69.54
mg/l
0.63
59
234
64
257
2.57
10.81
3.9
3.2
4.09
2.35
index
0.55
36
137
387
2819
1.54
10.63
3.0
2.2
2.86
2.77
mg/l
0.26
347
2450
362
2608
1.55
10.41
1.8
1.7
—
—
—
0
0
720
6001
1.48
10.05
6.5
5.2
6.48
6.56
mmol/l
0.50
694
5636
297
2062
1.58
10.00
1.4
1.3
23.86
28.86
iu/ml
0.57
84
613
42
143
3.01
9.68
3.2
3.1
1.17
1.52
%
0.31
36
132
670
5529
1.46
9.68
4.2
3.1
119.50
107.03
ug/l
0.73
634
5227
91
451
2.10
9.49
1.5
1.4
—
—
—
0
0
407
3056
1.50
9.47
2.4
2.2
198.43
239.85
u/l
0.40
390
2920
113
614
1.93
9.12
5.6
3.9
1.69
1.75
mmol/l
0.06
85
450
126
712
1.86
9.02
2.2
1.7
—
—
—
0
0
27
74
3.71
8.75
1.8
2.5
363.25
532.59
e6/l
0.99
20
56
27
74
3.71
8.75
2.1
2.6
194.29
233.12
e6/l
0.38
21
60
191
1228
1.66
8.71
2.2
1.8
—
—
—
0
0
227
1525
1.60
8.67
1.8
1.7
1203.81
1180.78
nmol/l
0.16
181
1174
65
292
2.29
8.65
1.9
1.6
—
—
—
0
0
63
280
2.32
8.59
1.4
1.3
241.15
243.95
u/ml
0.02
43
164
63
280
2.32
8.59
1.9
1.6
—
—
—
0
0
55
232
2.43
8.43
2.0
1.5
167.73
151.89
au/ml
0.41
15
72
25
68
3.73
8.20
1.7
2.5
—
—
—
0
0
30
93
3.28
8.11
2.4
3.1
57.60
57.03
%
0.05
24
85
182
1178
1.64
8.06
2.3
1.8
—
—
—
0
0
71
341
2.15
8.05
3.2
2.4
99.32
93.73
%
1.48
71
330
57
251
2.33
7.96
2.0
3.8
1.21
2.57
ratio
2.35
29
146
419
3259
1.43
7.80
3.5
2.6
57.44
62.01
u/l
0.84
390
3044
169
1084
1.65
7.75
7.3
9.2
0.57
0.91
mmol/l
0.52
140
905
349
2636
1.45
7.57
3.8
3.3
1542.08
1196.14
ng/l
0.70
297
2229
264
1899
1.50
7.31
1.3
1.3
10.47
12.48
u/ml
0.20
93
752
393
3064
1.42
7.09
6.0
3.8
0.00
0.01
estimate
1.34
138
1118
150
956
1.65
7.04
3.2
2.3
0.20
0.22
g/l
1.55
140
895
124
758
1.71
6.81
3.5
2.6
69.40
69.82
ml/min/173m2
0.04
63
304
459
3712
1.38
6.55
4.5
3.6
31.14
56.03
ng/l
0.78
325
2390
45
201
2.29
6.14
1.3
1.6
—
—
—
0
0
153
1014
1.58
6.11
3.1
2.5
38.42
84.97
u/l
0.48
143
853
220
1579
1.48
6.08
2.7
2.7
93.32
115.92
ug/g
1.06
191
1266
97
572
1.76
6.07
1.9
1.7
—
—
—
0
0
426
3448
1.36
5.91
4.7
3.3
2.35
2.35
mmol/l
0.27
395
3158
254
1905
1.42
5.53
5.2
3.7
646.73
477.39
ng/l
0.14
186
1372
36
153
2.39
5.52
1.2
1.1
117.39
114.74
%
0.18
36
141
38
167
2.32
5.41
1.1
1.1
—
—
—
0
0
68
374
1.87
5.36
2.1
1.7
1.35
2.11
ug/l
0.31
59
331
27
101
2.71
5.36
2.3
1.7
—
—
—
0
0
515
4339
1.32
5.30
5.7
3.5
0.02
0.03
estimate
0.11
128
1018
522
4407
1.32
5.29
2.2
2.0
94.61
96.80
pmol/l
0.49
295
2368
42
195
2.19
5.27
7.0
3.0
9.72
8.09
pmol/l
0.54
42
195
29
114
2.58
5.23
2.2
1.7
—
—
—
0
0
42
197
2.17
5.14
1.3
1.4
—
—
—
0
0
150
1029
1.52
5.14
9.1
6.6
—
—
—
0
0
126
832
1.57
5.12
1.5
1.3
188.64
243.19
u/ml
0.53
114
783
51
261
2.00
4.99
1.5
1.4
—
—
—
0
0
34
148
2.33
4.97
1.4
1.3
—
—
—
0
0
65
363
1.83
4.91
1.6
1.3
—
—
—
0
0
322
2557
1.35
4.90
2.8
2.3
—
—
—
0
0
1098
10399
1.51
4.88
25.3
14.3
21.22
22.73
mg/l
0.99
977
8509
18
57
3.19
4.77
1.1
1.2
820.00
1000.00
titre
—
5
10
49
252
1.98
4.74
1.3
1.4
—
—
—
0
0
29
121
2.43
4.66
1.2
1.1
98.59
96.95
%
0.13
29
111
169
1212
1.46
4.66
3.0
2.5
8.05
7.83
umol/l
0.05
149
1062
351
2842
1.33
4.65
1.4
1.3
1.87
1.60
u/ml
0.12
110
795
99
632
1.62
4.65
8.6
11.2
1.26
1.31
%
0.19
99
627
26
104
2.53
4.56
1.9
1.8
64.59
60.68
%
0.20
17
75
1092
10358
1.48
4.53
27.4
16.4
3.95
3.95
mmol/l
0.24
1076
10140
8
8
10.06
4.52
1.1
1.0
—
—
—
0
0
1090
10340
1.47
4.47
27.0
16.3
139.41
139.62
mmol/l
2.20
1074
10148
50
265
1.92
4.45
1.6
1.6
—
—
—
0
0
23
89
2.61
4.32
3.7
2.9
16.13
12.81
index
0.42
16
63
96
620
1.59
4.31
8.8
11.6
94.39
94.14
%
0.23
96
615
130
906
1.49
4.15
8.9
8.9
1.31
1.34
mmol/l
0.12
130
888
44
230
1.95
4.10
1.2
1.1
2.96
18.25
au/ml
—
9
69
25
104
2.43
4.07
1.0
1.1
—
—
—
0
0
15
47
3.22
4.06
1.1
1.1
—
—
—
0
0
22
88
2.53
3.89
2.9
2.2
—
—
—
0
0
136
970
1.45
3.87
3.6
3.0
—
—
—
0
0
40
207
1.96
3.85
1.3
1.4
—
—
—
0
0
61
363
1.72
3.78
3.2
1.9
—
—
—
0
0
15
50
3.02
3.69
1.6
1.1
—
—
—
0
0
9
16
5.66
3.66
1.0
1.4
—
—
—
0
0
1036
9811
1.35
3.66
21.3
13.5
83.86
86.44
ml/min/173m2
2.80
981
8969
29
136
2.16
3.63
1.4
1.6
—
—
—
0
0
344
2864
1.28
3.57
1.8
1.6
19.81
20.13
nmol/l
0.13
306
2468
432
3704
1.26
3.50
3.7
3.1
34.81
32.76
u/l
0.30
409
3517
45
251
1.82
3.49
1.6
1.7
15683.06
13994.37
e6/l
0.13
34
181
308
2536
1.29
3.48
5.7
3.8
1.02
1.62
kg/l
0.50
230
1668
238
1897
1.32
3.43
3.2
2.9
2.46
2.44
mmol/l
1.76
215
1692
35
181
1.96
3.41
2.3
1.7
—
—
—
0
0
53
314
1.72
3.37
1.3
1.1
2.93
4.13
—
10
51
37
197
1.91
3.32
1.3
1.6
—
—
—
0
0
17
65
2.64
3.31
1.1
1.1
1810.18
1523.15
miu/ml
0.52
17
65
55
334
1.68
3.21
2.6
1.8
—
—
—
0
0
14
49
2.88
3.19
1.2
1.6
2.50
2.01
umol/l
0.47
14
44
15
55
2.75
3.16
1.3
3.8
1035.13
628.07
u/ml
0.47
15
55
68
439
1.58
3.13
1.8
1.8
—
—
—
0
0
38
209
1.84
3.11
1.3
1.4
—
—
—
0
0
14
50
2.82
3.09
1.6
1.1
—
—
—
0
0
550
4891
1.22
3.08
3.3
2.7
—
—
estimate
—
0
0
108
773
1.44
3.05
1.6
1.4
—
—
—
0
0
50
301
1.69
3.03
3.4
3.0
—
—
—
0
0
5
5
10.03
2.98
2.0
1.6
—
—
—
0
0
16
63
2.56
2.96
4.0
2.9
0.75
0.81
index
0.15
16
63
817
7584
1.23
2.94
3.7
3.4
—
—
—
0
0
101
720
1.44
2.92
2.5
2.4
11.21
18.88
au/ml
1.17
11
81
11
32
3.46
2.90
2.7
2.5
2.55
2.34
ratio
0.11
11
27
20
90
2.24
2.81
2.6
1.4
—
—
—
0
0
20
90
2.24
2.81
2.6
1.4
—
—
—
0
0
20
90
2.24
2.81
2.6
1.4
—
—
—
0
0
62
403
1.57
2.80
1.7
1.5
4.49
0.08
iu/ml
0.49
14
55
378
3261
1.23
2.78
4.8
3.0
0.12
0.09
estimate
0.09
110
972
30
159
1.91
2.77
3.0
3.5
0.83
0.83
nmol/l
0.01
21
133
26
132
1.99
2.71
1.3
1.3
0.52
14.28
nmol/l
0.50
26
124
46
280
1.67
2.70
1.5
1.2
—
—
—
0
0
103
750
1.41
2.67
6.5
3.5
1.22
1.23
mmol/l
0.41
94
645
11
35
3.16
2.64
2.5
1.3
88.55
80.29
nmol/24h
0.14
11
35
7
15
4.69
2.60
12.7
5.5
6.11
7.33
mmol/l
—
7
15
30
163
1.86
2.59
1.4
1.5
—
—
—
0
0
20
94
2.15
2.55
1.3
1.4
1457.50
223780.62
e6/l
1.33
14
64
801
7479
1.20
2.47
4.1
3.3
51.30
43.35
u/l
2.02
764
7147
99
727
1.39
2.46
2.9
2.3
6.49
7.53
ug/l
0.20
84
648
10
32
3.14
2.44
1.2
2.6
0.63
0.61
mmol/l
—
10
32
943
8957
1.23
2.38
28.2
17.6
13.73
13.46
%
7.95
935
8855
14
58
2.43
2.37
1.9
3.8
104.00
121.00
umol/l
—
6
31
5
8
6.27
2.37
1.2
1.4
—
—
—
0
0
8
22
3.65
2.36
1.1
1.6
96.00
98.18
%
—
8
22
13
52
2.52
2.36
3.5
1.4
—
—
—
0
0
13
52
2.52
2.36
3.5
1.4
—
—
—
0
0
13
52
2.52
2.36
3.5
1.4
—
—
—
0
0
13
52
2.52
2.36
3.5
1.4
—
—
—
0
0
26
140
1.88
2.33
1.2
1.2
—
—
—
0
0
33
192
1.74
2.31
1.2
1.2
—
—
—
0
0
33
194
1.72
2.24
1.5
1.3
—
—
—
0
0
33
194
1.72
2.24
1.5
1.3
—
—
—
0
0
878
8302
1.20
2.22
4.8
4.3
14.63
14.62
pmol/l
0.05
819
7720
11
41
2.70
2.21
1.7
1.1
—
—
—
0
0
11
41
2.70
2.21
1.7
1.1
—
—
—
0
0
241
2031
1.23
2.18
1.7
1.7
434.37
27876787.17
pmol/l
1.92
212
1747
7
19
3.70
2.15
1.1
1.2
—
—
—
0
0
10
36
2.79
2.14
6.1
5.2
—
—
—
0
0
13
55
2.38
2.12
3.2
1.8
137.54
97.93
ng/l
0.54
13
55
20
102
1.98
2.11
4.0
2.4
19.20
19.57
mg/l
—
5
41
12
49
2.46
2.10
1.0
1.1
—
14.80
—
0
5
23
124
1.87
2.08
2.3
1.3
—
—
—
0
0
23
124
1.87
2.08
2.3
1.3
—
—
—
0
0
18
89
2.04
2.06
1.8
1.7
—
—
—
0
0
91
682
1.36
2.04
3.5
3.0
247.74
188.03
ng/l
0.78
81
623
23
125
1.86
2.03
2.3
1.3
—
—
—
0
0
21
111
1.91
2.01
1.0
1.1
—
—
—
0
0
1128
10982
1.32
2.00
30.1
17.8
84.70
75.33
umol/l
5.78
1120
10869
25
141
1.79
1.98
1.6
1.6
—
—
—
0
0
72
522
1.40
1.97
1.6
1.4
—
—
—
0
0
45
298
1.53
1.95
1.3
1.2
—
—
—
0
0
5
11
4.56
1.94
3.2
2.0
—
—
—
0
0
10
39
2.58
1.94
4.1
1.5
—
—
—
0
0
10
39
2.58
1.94
4.1
1.5
—
—
—
0
0
33
203
1.64
1.93
2.8
2.5
17.06
16.41
%
0.56
33
197
67
483
1.41
1.90
5.8
4.1
53.46
47.46
%
1.16
67
471
45
301
1.51
1.87
1.3
1.2
—
—
—
0
0
23
129
1.80
1.86
2.3
1.3
—
—
—
0
0
6
17
3.54
1.84
1.2
1.0
—
—
—
0
0
14
66
2.13
1.82
1.1
1.2
—
—
—
0
0
23
131
1.77
1.78
2.3
1.3
—
—
—
0
0
23
131
1.77
1.78
2.3
1.3
—
—
—
0
0
14
67
2.10
1.76
1.4
1.4
16.02
24.70
umol/l
0.67
14
60
68
500
1.38
1.74
1.2
1.3
239.50
220.31
miu/ml
0.16
30
248
47
324
1.47
1.71
1.9
1.3
—
—
—
0
0
11
48
2.30
1.70
1.1
1.1
—
—
—
0
0
19
104
1.84
1.68
1.4
1.4
33.23
32.39
g/l
0.08
19
93
23
134
1.73
1.67
2.0
1.5
29.93
24.95
ng/l
0.48
23
134
10
40
2.51
1.66
4.1
1.5
—
—
—
0
0
10
42
2.39
1.62
4.8
3.1
2.20
1.05
%
—
10
42
45
312
1.46
1.61
1.4
1.4
313.32
302.59
ug/g
0.12
25
181
1118
10917
1.26
1.58
17.4
11.0
27.10
26.48
u/l
0.63
1103
10667
10
44
2.28
1.55
1.4
2.3
44.10
69.44
ug/l
—
10
44
5
15
3.34
1.52
1.2
1.0
96.00
64.00
titre
—
5
15
31
202
1.55
1.49
1.6
1.3
18.73
22.97
u/l
0.37
20
169
116
945
1.25
1.47
2.3
2.3
12.95
13.13
nmol/l
0.09
100
867
9
38
2.38
1.45
1.1
1.2
—
—
—
0
0
9
39
2.32
1.43
1.3
1.2
—
—
—
0
0
1002
9706
1.17
1.40
5.9
5.3
1.83
1.84
mu/l
0.02
953
9126
9
40
2.26
1.40
2.0
1.7
—
—
—
0
0
5
17
2.95
1.36
1.2
1.2
—
—
—
0
0
12
61
1.98
1.33
1.3
1.4
—
66.00
—
0
10
5
18
2.78
1.28
1.6
3.3
75.60
76.46
%
—
5
13
5
18
2.78
1.28
1.0
1.0
6.50
7.50
u/ml
—
5
18
79
626
1.28
1.28
1.4
1.4
—
—
—
0
0
12
63
1.91
1.23
1.3
1.4
—
290.00
—
0
5
80
644
1.26
1.16
1.5
2.4
252.75
6422.83
u/l
5.15
23
260
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
51
1.97
1.11
1.0
1.1
—
—
—
0
0
8
41
1.96
1.09
3.0
2.3
—
—
—
0
0
33
236
1.41
1.07
1.3
1.3
—
—
—
0
0
51
393
1.31
1.05
1.5
1.5
—
—
—
0
0
5
22
2.28
1.03
1.4
1.1
—
—
—
0
0
5
22
2.28
1.03
1.4
1.1
—
—
—
0
0
11
60
1.84
1.03
1.4
1.2
—
—
—
0
0
18
114
1.59
1.03
1.1
1.2
—
—
titre
—
0
0
30
213
1.42
1.02
1.5
1.6
—
—
—
0
0
7
36
1.95
0.97
1.0
1.0
—
—
—
0
0
7
36
1.95
0.97
1.3
2.3
—
—
—
0
0
972
9468
1.13
0.95
7.0
5.7
38.68
38.54
mmol/mol
0.19
929
8988
14
85
1.65
0.94
1.1
1.1
299.71
291.73
mg/l
0.13
14
77
992
10145
0.89
0.92
5.5
4.6
4.56
4.65
mmol/l
2.33
946
9614
9
52
1.74
0.92
1.0
1.6
—
83.78
%
—
0
9
209
1878
1.14
0.92
1.7
1.5
—
—
—
0
0
69
564
1.24
0.92
1.5
1.6
0.22
0.30
mg/l
1.09
44
269
988
10103
0.89
0.90
5.3
4.6
1.41
1.45
mmol/l
2.67
936
9519
26
185
1.41
0.90
2.0
2.0
5.12
4.92
mmol/24h
0.11
21
167
23
160
1.45
0.89
2.2
1.5
321.23
334.41
mu/l
0.06
15
136
29
211
1.38
0.89
2.5
2.4
142.39
101.33
ug/min
0.23
19
128
13
79
1.65
0.88
1.3
1.3
65663.86
115486.95
e6/l
—
7
41
33
246
1.35
0.88
1.5
1.6
115.59
436.95
e6/l
0.48
27
189
20
136
1.48
0.87
1.2
1.0
—
—
—
0
0
8
44
1.82
0.86
1.0
1.2
—
—
—
0
0
12
72
1.67
0.85
1.2
1.4
—
—
—
0
0
130
1138
1.16
0.84
4.7
4.4
30.72
31.69
%
0.47
102
791
58
471
1.24
0.83
5.1
3.2
1.02
1.02
ratio
0.25
52
436
36
466
0.77
0.83
1.6
1.6
58.33
62.65
ug/l
0.27
30
389
54
437
1.25
0.81
1.5
1.5
9.80
8.87
u/l
0.16
37
348
40
312
1.29
0.80
3.4
4.2
1.24
1.34
mmol/l
0.34
40
305
33
429
0.76
0.79
1.6
1.5
1.09
1.21
ratio
0.31
21
261
33
429
0.76
0.79
1.6
1.5
1.11
1.19
ratio
0.24
21
261
33
429
0.76
0.79
1.6
1.5
0.89
0.94
ratio
0.45
21
261
14
90
1.56
0.78
1.3
1.2
—
—
—
0
0
52
421
1.25
0.78
1.6
1.7
8.88
8.44
u/ml
0.06
16
101
82
696
1.19
0.78
3.7
3.6
4.71
4.59
pmol/l
0.25
73
624
18
123
1.47
0.77
1.9
2.0
31.50
32.47
pg
0.36
18
123
32
243
1.33
0.77
1.4
1.5
1.33
10.20
e6/l
2.07
24
178
14
91
1.54
0.75
1.3
1.2
—
—
—
0
0
84
718
1.18
0.75
1.4
1.5
18.83
23.74
iu/l
0.95
72
604
93
1074
0.85
0.75
1.7
1.6
3.54
3.45
mmol/l
0.28
57
754
13
84
1.55
0.72
1.2
1.6
13.96
12.15
umol/l
0.48
13
76
33
420
0.78
0.70
1.6
1.5
—
—
—
0
0
31
239
1.30
0.69
2.5
2.4
131.83
129.94
g/l
0.19
23
195
16
111
1.45
0.66
7.6
7.2
5.80
7.01
mmol/l
1.45
11
91
42
344
1.23
0.60
1.7
1.8
—
—
—
0
0
46
381
1.22
0.60
1.5
1.5
—
—
—
0
0
6
38
1.58
0.54
1.3
1.1
—
—
—
0
0
11
75
1.47
0.50
1.1
1.4
137.54
178.98
pmol/l
0.60
11
75
13
92
1.42
0.50
1.2
1.1
107.31
107.60
pmol/l
0.01
13
92
128
1401
0.90
0.49
2.1
1.9
3.62
3.51
ratio
0.40
94
1072
12
84
1.43
0.49
27.8
13.7
0.60
0.62
mmol/l
0.15
12
76
1012
10261
0.92
0.49
5.9
5.2
2.66
2.75
mmol/l
2.68
960
9681
22
172
1.28
0.48
2.6
4.2
351.71
1723.70
u/ml
0.48
17
163
17
128
1.33
0.47
1.2
1.3
—
—
—
0
0
10
69
1.45
0.44
1.1
1.2
—
—
—
0
0
13
95
1.37
0.43
3.5
4.2
—
—
—
0
0
6
92
0.65
0.42
1.7
1.5
—
—
—
0
0
29
240
1.21
0.41
2.4
1.4
0.30
0.37
nmol/l
0.21
20
193
0
15
0.00
0.41
0.0
8.6
—
10.79
—
0
15
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
5
35
1.43
0.39
1.4
1.8
44.18
41.05
g/l
—
5
35
0
19
0.00
0.39
0.0
1.2
—
3.32
—
0
12
97
886
1.10
0.39
4.7
4.5
7.55
23.06
ug/l
0.94
73
723
5
36
1.39
0.38
1.0
1.4
9.34
8.70
ug/l
—
5
36
9
68
1.33
0.37
1.0
1.6
—
1224609.80
—
0
5
10
72
1.39
0.37
1.2
1.2
10.60
8.86
mm/h
—
10
72
27
320
0.84
0.35
1.7
2.1
7.05
4.21
iu/l
0.54
14
136
6
43
1.40
0.35
1.0
2.0
—
—
—
0
0
6
43
1.40
0.35
1.0
2.0
—
—
—
0
0
27
227
1.19
0.34
1.1
1.1
10.64
6.59
u/ml
—
8
101
6
44
1.37
0.34
1.5
1.4
—
—
—
0
0
24
200
1.20
0.34
1.0
1.0
1.54
2.02
eliau/ml
—
5
88
6
47
1.28
0.32
1.2
1.1
38.97
50.48
u/ml
—
6
47
11
83
1.33
0.32
1.2
1.1
—
—
—
0
0
34
296
1.15
0.30
1.5
1.6
56.83
57.63
ug/l
0.04
34
296
13
102
1.28
0.30
1.0
1.1
—
—
—
0
0
27
231
1.17
0.30
1.2
1.2
—
—
—
0
0
43
479
0.89
0.27
1.7
1.9
2.74
4.15
mg/l
1.15
36
349
22
187
1.18
0.26
1.1
1.1
294.24
122.05
iu/ml
—
9
43
14
113
1.24
0.26
1.1
1.2
—
—
—
0
0
160
1521
1.06
0.26
2.1
1.8
1.53
1.43
%
0.83
146
1369
1151
11449
1.08
0.26
36.1
21.6
7.20
6.72
e9/l
9.18
1137
11231
1151
11449
1.08
0.26
36.2
21.8
134.20
136.18
g/l
4.76
1142
11350
9
74
1.22
0.25
1.1
1.5
—
—
—
0
0
10
78
1.28
0.24
1.7
1.3
100.20
75.78
umol/l
—
10
78
72
668
1.08
0.24
1.1
1.0
—
—
—
0
0
1150
11442
1.08
0.24
35.9
21.5
90.51
90.51
fl
0.02
1144
11346
23
199
1.16
0.23
1.6
1.7
—
—
—
0
0
32
285
1.13
0.22
1.1
1.1
1.90
1.53
u/ml
0.08
12
130
1150
11445
1.07
0.22
36.0
21.6
4.49
4.54
e12/l
2.73
1135
11234
1150
11445
1.07
0.22
36.7
22.1
40.37
41.37
%
1.11
1144
11341
46
503
0.91
0.22
1.1
1.1
1.47
1.53
g/l
1.15
46
503
281
2726
1.04
0.22
4.6
5.0
1.73
2.33
ug/l
1.90
252
2477
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.9
—
0.46
—
0
13
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
6
53
1.13
0.18
1.5
1.5
—
—
—
0
0
7
61
1.15
0.17
1.4
1.5
—
—
—
0
0
421
4289
0.97
0.17
2.1
1.9
1.43
1.36
mmol/l
0.91
369
3704
1148
11439
1.05
0.15
36.2
21.6
253.43
254.11
e9/l
0.13
1133
11248
9
80
1.13
0.15
1.4
1.6
—
—
—
0
0
18
159
1.13
0.15
4.9
3.6
58.78
24.79
u/ml
0.41
18
154
11
93
1.18
0.14
1.4
1.3
6.32
6.43
mmol/l
0.05
11
88
13
112
1.16
0.14
1.2
1.1
14.43
15.97
u/ml
—
6
53
32
295
1.09
0.14
1.1
1.1
5.52
7.21
u/ml
0.25
16
166
59
559
1.06
0.13
2.0
1.6
337.30
293.38
mu/l
0.56
53
504
13
113
1.15
0.13
1.2
1.1
—
—
—
0
0
168
1634
1.03
0.13
2.9
3.0
0.70
0.74
ug/l
0.22
100
974
20
221
0.90
0.12
4.7
3.7
23.52
26.43
mg/l
0.20
14
151
24
219
1.10
0.12
1.2
1.1
0.11
0.39
u/ml
—
5
73
31
287
1.08
0.12
1.2
1.1
0.22
2.18
u/ml
3.80
11
150
22
200
1.10
0.12
1.1
1.3
—
—
—
0
0
22
201
1.10
0.11
5.1
3.2
7.80
7.53
mmol/l
0.13
22
194
972
9765
0.98
0.10
5.6
4.6
5.85
5.83
mmol/l
0.12
919
9087
41
388
1.06
0.10
1.7
1.6
—
—
—
0
0
97
1001
0.97
0.10
2.4
2.0
—
—
—
0
0
10
87
1.15
0.09
1.0
1.8
—
1131.84
—
0
14
5
47
1.06
0.09
4.0
2.1
209.60
146.98
nmol/l
—
5
42
6
57
1.05
0.08
1.5
1.5
—
—
—
0
0
89
869
1.03
0.06
1.3
1.2
164.21
140.44
u/ml
0.17
34
353
219
2163
1.02
0.06
3.7
4.2
22.64
21.55
%
0.41
90
931
117
1192
0.98
0.06
2.5
2.2
—
—
—
0
0
915
9121
1.01
0.05
29.8
17.9
331.72
332.99
g/l
4.20
909
9076
80
816
0.98
0.04
1.5
1.6
815.77
1005.46
mu/l
1.18
67
685
954
9562
0.99
0.04
4.6
3.9
1.38
1.26
mmol/l
3.94
906
8941
10
92
1.09
0.03
1.5
1.5
—
—
—
0
0
51
521
0.98
0.03
1.3
1.5
—
—
—
0
0
182
1830
0.99
0.01
2.7
2.2
—
—
—
0
0
25
244
1.03
0.00
4.9
3.0
1.40
1.55
mmol/l
0.59
25
236
13
127
1.02
0.00
1.3
2.1
—
—
—
0
0
34
335
1.02
0.00
1.2
1.1
0.54
3.38
u/ml
3.95
16
181
198
1985
1.00
0.00
2.7
2.3
—
—
—
0
0
6
65
0.92
-0.00
5.2
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
721.60
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
9.14
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.00
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_ALLERGPURPURA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_ALLERGPURPURA | 1.684 [1.48, 1.91] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.726 |
During the follow-up period (1.1.1998 — 31.12.2019), 714 out of 4075 females with D3_ALLERGPURPURA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_ALLERGPURPURA | 2.061 [1.77, 2.4] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 715 out of 3988 males with D3_ALLERGPURPURA died.
Mortality risk
Mortality risk for people of age
years, who have D3_ALLERGPURPURA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.196% | 0.383% |
| 5 | 1.231% | 2.411% |
| 10 | 2.985% | 5.958% |
| 15 | 5.514% | 11.65% |
| 20 | 9.794% | 19.138% |
Relationships between endpoints
↥Index endpoint: D3_ALLERGPURPURA – Allergic purpura
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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