Whooping cough, including avohilmo

AB1_WHOOPCOUGH_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 A37
  • Hospital discharge: ICD-10 A37
  • Hospital discharge: ICD-9 03[3]
  • Hospital discharge: ICD-8 03[3]
  • Cause of death: ICD-10 A37
  • Cause of death: ICD-9 03[3]
  • Cause of death: ICD-8 03[3]

3 out of 7 registries used, show all original rules.

764

4. Check minimum number of events

None

764

5. Include endpoints

None

764

6. Filter based on genotype QC (FinnGen only)

686

Control definitions (FinnGen only)

Control exclude
AB1_OTHER_BACTERIAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 686 495 191
Unadjusted period prevalence (%) 0.15 0.18 0.09
Median age at first event (years) 42.86 41.80 45.61

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
719
Matched controls
7190
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A37.0
ICD-10 Finland
Whooping cough due to Bordetella pertussis
+∞
251.2
226
*
A37.9
ICD-10 Finland
Whooping cough, unspecified
+∞
229.9
208
*
A37
ICD-10 Finland
Whooping cough
+∞
205.3
187
*
R05
ICD-10 Finland
Cough
3.6
57.2
269
1019
R71
ICPC
Whooping cough
182.7
49.5
51
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
17.5
42.1
35
21
J01FA10
ATC
azithromycin; systemic
3.3
40.1
562
3741
R05
ICPC
Cough
2.8
37.8
282
1340
R053, ,
ICD-10 Finland
5.0
33.0
75
163
A37.1
ICD-10 Finland
Whooping cough due to Bordetella parapertussis
+∞
31.5
30
*
R03AC02
ATC
salbutamol; inhalant
2.4
25.9
482
3315
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.6
24.6
186
863
03397
ICD-8 Finland
Whooping cough, Suspecta
+∞
23.0
22
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.3
20.6
527
3942
J45.9
ICD-10 Finland
Asthma, unspecified
2.4
20.5
168
802
03300
ICD-8 Finland
Whooping cough, Bordetalla Pertussis
+∞
19.9
19
*
J01FA06
ATC
roxithromycin; oral
2.1
19.9
296
1800
GD1AA, ,
SPAT
2.2
17.2
180
947
R03AK07
ATC
formoterol and budesonide; inhalant
2.1
15.9
191
1057
J20
ICD-10 Finland
Acute bronchitis
2.6
15.7
104
446
0330A
ICD-9 Finland
Whooping cough, Bordetella pertussis [B. pertussis][PERTUSSIS CAUSA BORDETELLA PERTUSSIS,EI ROKOTETULLA]
+∞
15.7
15
*
J45
ICD-10 Finland
Asthma
2.5
15.4
104
450
H02AB06
ATC
prednisolone; systemic
1.9
15.2
317
2116
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.4
14.6
108
487
R03DC03
ATC
montelukast; oral
2.1
14.4
155
818
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.5
14.2
98
428
R01AD09
ATC
mometasone; nasal
1.8
13.4
376
2716
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
13.3
311
2128
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.1
13.3
146
776
03399
ICD-8 Finland
Whooping cough, Other and unspecified
+∞
12.5
12
*
0330B
ICD-9 Finland
Whooping cough, Bordetella pertussis [B. pertussis][PERTUSSIS CAUSA BORDETELLA PERTUSSIS,ROKOTETULLA]
+∞
12.5
12
*
R03AC03
ATC
terbutaline; inhalant
2.2
12.5
114
562
R03AC12
ATC
salmeterol; inhalant
3.9
12.0
35
92
R49.0
ICD-10 Finland
Dysphonia
4.3
11.9
31
75
A46
ICD-10 Finland
Erysipelas
3.3
11.9
46
147
R03BA02
ATC
budesonide; inhalant
2.0
11.5
149
836
H02AB04
ATC
methylprednisolone; systemic
2.3
11.5
96
456
R03BC03
ATC
nedocromil; inhalant
2.8
11.3
56
207
R03BA05
ATC
fluticasone; inhalant
1.9
11.1
153
876
R01AD58
ATC
fluticasone, combinations; nasal
1.8
10.8
236
1562
J46
ICD-10 Finland
Status asthmaticus
4.2
10.7
28
68
J45.1
ICD-10 Finland
Nonallergic asthma
2.7
10.4
58
228
M79.6
ICD-10 Finland
Pain in limb
1.7
10.2
320
2327
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
10.1
235
1576
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
10.0
226
1502
R06AE07
ATC
cetirizine; oral
1.7
10.0
338
2504
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.6
9.9
59
240
J01AA02
ATC
doxycycline; systemic
1.7
9.8
503
4137
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
9.8
253
1742
N02AX02
ATC
tramadol; systemic, rectal
1.7
9.3
253
1761
J01DB01
ATC
cefalexin; oral
1.9
9.3
590
5110
R06.0
ICD-10 Finland
Dyspnoea
1.8
9.2
170
1064
R01AD08
ATC
fluticasone; nasal
1.7
9.1
221
1491
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
9.1
161
993
A02BC05
ATC
esomeprazole; systemic
1.6
8.8
255
1802
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
8.7
88
450
48609
ICD-8 Finland
Pneumonia, unspecified
4.9
8.6
19
40
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
+∞
8.3
8
*
R53
ICD-10 Finland
Malaise and fatigue
1.7
7.9
196
1324
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
3.0
7.8
33
112
R74
ICPC
Upper respiratory infection acute
1.6
7.7
330
2538
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
+∞
7.3
7
*
J01FA09
ATC
clarithromycin; systemic
1.6
7.3
224
1590
Z01.7
ICD-10 Finland
Laboratory examination
1.8
7.2
128
788
Z71.8
ICD-10 Finland
Other specified counselling
1.5
7.1
276
2063
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
7.0
180
1223
R03BA01
ATC
beclometasone; inhalant
1.9
6.9
92
518
M54.5
ICD-10 Finland
Low back pain
1.5
6.9
269
2013
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
6.8
84
462
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
6.7
388
3148
J02AC01
ATC
fluconazole; systemic
1.5
6.7
293
2244
R03AC13
ATC
formoterol; inhalant
2.8
6.6
32
117
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
6.6
213
1524
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
6.6
225
1632
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.4
293
2257
ZXE00
NOMESCO Finland
One hour or less
1.5
6.4
255
1909
J01FA01
ATC
erythromycin; systemic
1.8
6.4
111
678
K02.1
ICD-10 Finland
Caries of dentine
1.5
6.4
466
3948
R06AX13
ATC
loratadine; oral
1.7
6.3
121
760
0339A
ICD-9 Finland
Whooping cough, unspecified organism[PERTUSSIS NUD, EI ROKOTETULLA]
+∞
6.3
6
*
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.6
6.3
164
1116
S06.0
ICD-10 Finland
Concussion
1.9
6.2
84
476
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.6
6.1
34
134
Z2221
NOMESCO Finland
Medical doctor
1.6
6.1
189
1338
R96
ICPC
Asthma
2.0
6.0
62
319
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.9
6.0
78
435

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
134
72
22.65
174.06
1.2
1.1
—
—
—
0
0
128
73
21.12
161.56
1.1
1.0
19.15
6.09
iu/ml
6.61
55
18
51
26
21.04
66.54
1.1
1.0
99.71
48.20
iu/ml
2.13
51
26
68
163
4.50
26.47
1.2
1.1
20.74
13.41
au/ml
0.46
22
54
51
136
3.96
17.19
1.2
1.2
—
—
—
0
0
235
1372
2.06
17.08
2.1
1.7
0.97
0.97
mg/l
0.00
179
1006
299
1936
1.93
15.91
6.5
5.6
—
—
—
0
0
408
3019
1.81
13.44
6.9
5.6
29.98
30.01
%
0.02
391
2885
396
2918
1.79
13.10
7.0
5.7
8.24
8.34
%
0.32
373
2759
395
2916
1.79
12.91
6.9
5.6
2.66
2.82
%
0.94
374
2747
394
2910
1.78
12.82
7.0
5.7
0.69
0.69
%
0.09
369
2732
432
3318
1.76
11.89
7.3
5.9
0.18
0.18
e9/l
0.17
371
2931
427
3271
1.75
11.84
7.1
5.7
1.98
1.98
e9/l
0.04
375
2922
418
3189
1.74
11.70
7.2
5.7
0.54
0.54
e9/l
0.07
360
2771
397
2990
1.73
11.60
6.9
5.6
56.06
55.95
%
0.07
384
2860
123
650
2.08
11.22
2.2
1.8
—
—
—
0
0
416
3196
1.72
11.11
7.2
5.7
0.04
0.04
e9/l
0.17
357
2777
168
1009
1.87
10.53
5.4
2.8
—
—
—
0
0
447
3545
1.69
10.21
9.7
7.6
4.05
3.93
e9/l
0.57
388
3069
103
545
2.04
9.29
1.4
1.3
125.60
242.59
u/ml
1.31
92
510
350
2664
1.61
8.92
3.8
3.0
6.35
6.21
ph
1.36
174
1538
679
6231
2.61
8.50
17.4
10.2
18.80
18.95
mg/l
0.05
592
4894
475
3938
1.61
8.11
5.4
3.8
338.91
811.31
e6/l
0.48
11
42
228
1598
1.62
7.94
3.0
2.4
—
—
—
0
0
118
692
1.84
7.82
3.7
2.1
24.56
24.04
%
0.15
104
643
412
3321
1.56
7.80
4.1
3.3
17.84
4.65
estimate
0.33
74
674
128
778
1.78
7.53
3.3
2.1
2.37
2.46
g/l
0.92
117
718
29
93
3.21
7.48
1.1
1.1
12.73
14.49
u/ml
0.19
15
43
406
3289
1.54
7.31
4.1
3.3
0.00
0.00
estimate
0.50
73
678
411
3341
1.54
7.27
4.1
3.3
0.04
0.00
estimate
0.42
70
648
505
4299
1.59
7.25
8.2
6.2
76.57
75.62
u/l
0.19
483
4082
191
1337
1.58
6.49
2.5
2.3
317.01
319.85
umol/l
0.17
179
1225
117
726
1.73
6.36
1.4
1.4
—
—
—
0
0
281
2169
1.49
5.99
5.2
3.3
26.39
84.61
e6/l
2.72
178
1377
132
861
1.65
5.95
3.4
2.1
13.77
14.77
umol/l
0.82
123
798
206
1494
1.53
5.91
5.1
3.3
7.40
7.39
ph
0.34
128
1031
144
963
1.62
5.87
1.4
1.4
497.39
514.20
titre
0.04
23
200
387
3199
1.45
5.70
5.3
4.1
6.40
6.29
mmol/l
0.45
363
2930
351
2850
1.45
5.67
11.5
8.5
0.00
0.00
e9/l
0.06
278
2316
280
2182
1.46
5.59
6.0
4.1
36.75
37.47
g/l
1.38
264
2070
104
647
1.71
5.59
2.1
1.4
—
—
—
0
0
173
1222
1.55
5.56
1.3
1.3
4.94
9.91
u/ml
0.88
77
506
338
2746
1.44
5.34
2.8
2.5
74.46
74.27
nmol/l
0.04
319
2575
421
3577
1.43
5.09
4.4
3.2
89.86
72.51
ug/l
1.85
401
3413
687
6508
2.25
5.01
12.8
9.4
—
—
—
0
0
204
1522
1.48
4.99
2.2
2.2
2.25
2.55
mg/l
2.11
170
1317
235
1802
1.45
4.99
3.6
2.6
2.35
2.36
mmol/l
0.47
217
1666
128
865
1.58
4.95
3.6
2.5
5.04
3.46
e6/l
0.71
59
389
282
2245
1.42
4.85
7.6
5.2
1.22
1.22
mmol/l
0.18
260
2080
181
1327
1.49
4.81
1.4
1.3
15.55
26.08
iu/ml
0.99
42
403
89
553
1.70
4.80
2.5
2.0
32.34
31.87
u/l
0.06
76
464
134
925
1.55
4.72
3.1
3.0
438.07
496.73
ng/l
0.07
78
550
186
1379
1.47
4.66
1.6
1.5
21.25
21.02
nmol/l
0.08
169
1215
311
2532
1.40
4.66
7.8
5.4
1.22
1.22
mmol/l
0.09
272
2212
219
1676
1.44
4.64
1.5
1.4
2.06
2.04
g/l
0.09
139
1051
338
2793
1.40
4.63
6.0
4.8
10.36
10.74
umol/l
0.35
323
2654
684
6490
2.11
4.61
18.4
12.1
72.92
69.54
umol/l
1.32
679
6426
645
6015
1.70
4.55
16.7
10.5
139.53
139.65
mmol/l
0.79
637
5906
240
1877
1.42
4.49
2.8
1.9
—
—
—
0
0
256
2026
1.41
4.47
14.4
7.7
1.16
1.12
inr
0.57
209
1671
710
6900
3.32
4.45
24.9
16.5
263.38
261.55
e9/l
0.31
701
6795
76
462
1.72
4.44
4.1
3.7
4.63
4.68
pmol/l
0.17
71
418
645
6026
1.68
4.38
17.2
10.6
3.91
3.92
mmol/l
0.40
635
5890
187
1403
1.45
4.37
2.8
1.8
—
—
—
0
0
279
2250
1.39
4.34
2.3
1.8
95.80
97.69
pmol/l
0.28
144
1213
684
6508
2.05
4.28
11.7
9.0
25.73
25.88
u/l
0.08
673
6367
30
134
2.29
4.21
1.8
1.4
125.00
130.59
au/ml
—
10
28
208
1602
1.42
4.20
5.3
4.1
—
—
—
0
0
225
1758
1.41
4.18
2.8
2.8
36.94
74.15
ng/l
0.35
99
901
93
606
1.61
4.18
1.4
1.4
21.66
22.40
iu/l
0.08
79
502
710
6908
3.22
4.18
24.9
16.5
6.74
6.65
e9/l
0.64
702
6785
710
6906
3.24
4.17
24.8
16.4
4.55
4.56
e12/l
0.41
702
6791
248
1972
1.39
4.16
1.4
1.4
2.17
2.01
u/ml
0.06
71
535
31
142
2.24
4.11
1.8
1.5
—
—
—
0
0
631
5882
1.59
4.09
6.3
5.3
1.71
1.78
mu/l
0.78
609
5612
131
928
1.50
4.07
2.5
2.2
2.43
2.42
mmol/l
0.36
121
829
104
702
1.56
4.03
1.4
1.4
—
—
—
0
0
195
1498
1.41
3.96
3.9
2.6
0.16
0.24
e6/l
1.07
133
1039
8
11
7.34
3.86
1.8
1.4
—
—
—
0
0
15
49
3.11
3.82
1.3
1.4
—
—
—
0
0
219
1738
1.37
3.63
4.2
2.7
35.64
55.50
e6/l
0.55
160
1264
559
5119
1.41
3.63
5.3
4.5
14.38
14.40
pmol/l
0.06
534
4805
87
578
1.57
3.62
9.3
5.9
104.51
104.99
mmol/l
0.46
87
578
70
441
1.65
3.61
5.1
4.4
0.90
0.72
%
0.19
20
98
36
185
2.00
3.59
1.1
1.2
—
—
—
0
0
190
1479
1.39
3.53
2.2
1.9
120.75
208.12
u/l
1.20
181
1413
583
5388
1.43
3.51
5.7
4.8
37.82
37.34
mmol/mol
0.65
564
5163
43
237
1.87
3.51
2.5
2.1
20.56
20.87
s
0.24
36
215
67
422
1.65
3.46
5.2
4.4
0.33
0.08
%
0.55
18
80
73
472
1.61
3.41
2.3
2.4
10.11
10.44
g/l
0.35
68
439
94
645
1.53
3.39
1.5
1.6
1192.23
1123.67
nmol/l
0.28
69
510
139
1035
1.43
3.32
2.8
3.1
952.99
642.72
ng/l
0.50
118
846
290
2429
1.32
3.31
2.0
2.0
—
—
—
0
0
46
269
1.76
3.13
1.2
1.1
2.33
3.71
u/ml
0.51
30
145
209
1681
1.34
3.12
2.5
2.3
48.88
62.01
u/l
2.82
194
1571
42
240
1.80
3.09
1.9
3.0
152.77
124.33
ng/l
0.24
35
219
94
659
1.49
3.07
2.4
2.4
6.33
6.18
umol/l
0.04
74
569
132
990
1.41
3.03
3.3
2.4
531.96
540.35
mosm/kgh2o
0.17
119
867
8
17
4.75
2.92
1.4
1.2
—
—
—
0
0
68
451
1.56
2.88
3.7
2.9
1.98
1.69
%
0.99
62
404
87
609
1.49
2.87
2.5
2.2
7956.34
6330.52
u/l
0.17
31
261
19
84
2.30
2.79
1.7
1.5
31.00
26.58
ng/l
0.16
19
84
222
1827
1.31
2.78
6.6
4.9
—
—
—
0
0
63
415
1.57
2.75
5.0
4.2
0.69
0.55
%
0.16
16
86
24
118
2.07
2.74
1.4
1.2
5.85
3.40
u/ml
0.31
13
48
73
498
1.52
2.73
2.0
2.0
6.37
6.23
ph
0.52
49
318
22
105
2.13
2.71
1.2
1.2
—
—
—
0
0
20
92
2.21
2.69
5.6
2.2
7.90
6.38
pmol/l
0.43
20
92
593
5568
1.37
2.65
21.2
13.1
13.35
13.28
%
0.85
587
5515
40
237
1.73
2.64
4.3
2.5
1.01
1.02
ratio
1.61
35
221
51
323
1.62
2.63
3.1
2.6
83.25
71.02
e9/l
0.95
33
216
30
163
1.88
2.61
1.4
1.4
170.42
211.41
u/ml
0.80
19
92
15
62
2.45
2.55
1.3
1.5
—
—
—
0
0
15
62
2.45
2.55
1.3
1.5
—
—
—
0
0
15
62
2.45
2.55
1.3
1.5
—
—
—
0
0
15
62
2.45
2.55
1.3
1.5
—
—
—
0
0
6
11
5.49
2.55
1.0
1.0
5.95
11.68
u/ml
—
6
11
70
481
1.50
2.54
2.3
2.3
7.22
17.97
au/ml
2.97
12
59
11
37
3.00
2.49
1.2
1.2
—
—
—
0
0
294
2538
1.27
2.48
3.8
3.1
0.00
0.03
estimate
1.95
61
570
232
1951
1.28
2.42
3.5
2.7
0.00
0.02
estimate
1.54
61
563
97
719
1.40
2.39
1.2
1.2
—
—
—
0
0
22
111
2.01
2.38
1.0
1.1
183.28
4601.39
iu/ml
—
6
28
23
118
1.98
2.38
6.0
2.4
1.33
2.55
index
—
9
60
37
223
1.69
2.32
1.2
1.1
—
—
—
0
0
137
1080
1.33
2.30
3.0
2.7
66.05
92.81
ug/g
1.41
117
860
19
92
2.09
2.29
4.5
2.5
—
—
—
0
0
41
256
1.64
2.26
1.7
1.7
24.21
8.52
u/ml
—
9
77
63
435
1.49
2.26
5.6
4.8
0.07
0.08
%
0.03
14
75
67
469
1.47
2.25
9.3
3.3
5.73
5.77
kpa
0.16
67
452
102
771
1.38
2.24
1.4
1.2
—
—
—
0
0
323
2844
1.25
2.24
3.2
2.5
—
—
estimate
—
0
0
9
29
3.13
2.23
2.8
2.7
—
—
—
0
0
8
24
3.36
2.18
1.3
1.3
—
—
—
0
0
143
1144
1.31
2.16
3.3
2.3
4.68
7.94
e6/l
2.83
132
1026
6
14
4.31
2.15
4.3
3.0
—
—
—
0
0
49
324
1.55
2.15
1.4
1.4
9.69
9.18
u/l
0.08
34
252
53
357
1.52
2.14
1.1
1.1
—
—
—
0
0
208
1749
1.27
2.14
3.5
3.2
8.20
8.37
mmol/l
0.19
188
1535
163
1331
1.29
2.12
1.6
1.6
—
—
—
0
0
50
334
1.53
2.10
4.9
4.2
7.41
7.41
ph
0.17
41
270
32
191
1.71
2.10
2.4
2.4
4.73
5.18
umol/l
0.15
26
148
39
247
1.61
2.05
5.8
2.6
127.90
133.27
g/l
0.87
39
236
65
461
1.45
2.05
2.0
1.6
322.66
300.96
mu/l
0.23
58
423
66
470
1.45
2.04
9.5
3.3
7.37
7.38
ph
0.65
42
246
167
1375
1.28
2.03
3.7
3.4
36.85
41.62
mg/l
0.15
111
908
281
2458
1.24
2.02
1.9
1.8
1.39
1.35
mmol/l
0.43
255
2184
15
70
2.17
1.99
1.4
1.3
—
—
—
0
0
5
11
4.57
1.94
1.2
1.1
—
—
—
0
0
5
11
4.57
1.94
1.0
1.0
—
—
—
0
0
5
11
4.57
1.94
1.2
1.2
—
—
—
0
0
38
243
1.60
1.94
1.2
1.1
7.33
5.58
u/ml
0.24
22
142
63
452
1.43
1.89
9.9
3.4
1.47
1.56
mmol/l
0.08
58
392
55
385
1.46
1.87
1.2
1.2
—
—
—
0
0
167
1388
1.26
1.87
4.7
4.1
6.10
7.31
mg/mmol
0.21
113
881
19
100
1.92
1.87
5.2
3.1
—
—
—
0
0
13
59
2.23
1.85
4.0
3.1
10.84
11.93
%
0.58
13
59
32
199
1.64
1.83
1.4
1.3
—
—
—
0
0
51
354
1.47
1.82
1.4
1.4
—
—
—
0
0
175
1469
1.25
1.80
2.0
1.9
—
—
—
0
0
36
233
1.57
1.77
1.2
1.1
0.17
0.78
u/ml
3.21
19
105
59
425
1.42
1.75
14.8
7.6
—
—
—
0
0
487
4545
1.22
1.74
3.3
3.0
34.72
35.95
u/l
0.24
468
4380
29
179
1.65
1.72
1.2
1.1
6.12
8.45
u/ml
0.24
17
78
17
89
1.93
1.71
4.9
3.3
3.76
4.03
e9/l
0.36
17
89
57
410
1.42
1.70
8.1
3.0
4.54
4.83
kpa
0.69
57
399
36
236
1.55
1.68
1.1
1.1
2.98
5.96
eliau/ml
—
5
42
202
1736
1.23
1.67
2.0
1.7
—
—
—
0
0
35
230
1.55
1.63
1.1
1.2
—
—
—
0
0
21
121
1.76
1.60
1.4
2.5
9.82
10.11
g/l
0.20
21
116
50
356
1.43
1.59
6.8
3.8
145.94
69.34
ng/l
1.37
43
326
15
78
1.94
1.55
2.9
1.9
17.35
16.99
%
0.21
15
78
84
658
1.31
1.50
1.3
1.4
—
—
—
0
0
16
87
1.86
1.47
2.4
2.2
—
—
—
0
0
16
87
1.86
1.47
1.8
1.6
1.03
3.74
ug/l
0.38
16
74
21
125
1.70
1.45
3.2
2.2
7.40
7.41
ph
1.47
21
125
28
180
1.58
1.45
1.3
1.3
—
—
—
0
0
46
329
1.43
1.45
1.4
1.3
—
—
—
0
0
6
22
2.74
1.43
1.2
1.3
0.01
0.73
u/ml
—
6
22
67
512
1.34
1.43
1.6
1.8
—
—
—
0
0
586
5617
1.23
1.40
4.4
4.0
5.69
5.66
mmol/l
0.26
563
5279
14
74
1.91
1.39
1.1
1.1
0.83
0.23
u/ml
—
6
29
80
1002
0.77
1.38
1.8
1.8
3.25
3.40
ratio
0.82
64
754
39
274
1.45
1.36
1.9
2.1
25.97
7.86
ug/l
0.42
34
247
15
83
1.82
1.32
1.7
1.3
—
—
—
0
0
20
121
1.67
1.32
1.7
2.3
—
10.80
—
0
5
6
24
2.51
1.30
1.5
1.3
27.83
27.67
s
—
6
24
18
106
1.72
1.30
1.1
1.0
—
—
—
0
0
18
106
1.72
1.30
2.4
1.6
3320.90
8996.52
e6/l
—
10
75
10
48
2.10
1.28
1.1
1.3
71.80
70.96
umol/l
—
10
48
239
2135
1.18
1.28
2.5
2.2
—
—
—
0
0
9
44
2.06
1.27
1.0
2.3
2.07
1.80
umol/l
—
9
39
80
639
1.28
1.26
1.3
1.3
165.42
151.30
u/ml
0.11
34
274
5
19
2.64
1.22
2.8
1.6
—
—
—
0
0
5
19
2.64
1.22
1.0
1.4
41.40
82.04
ng/l
—
5
19
102
844
1.24
1.21
1.8
1.6
935.35
991.77
mu/l
0.34
86
719
15
86
1.76
1.19
3.8
2.1
8.98
9.16
kpa
0.15
15
86
15
86
1.76
1.19
3.8
2.1
1.78
2.45
mmol/l
—
9
51
15
86
1.76
1.19
3.8
2.1
5.21
4.90
kpa
1.83
15
86
23
149
1.56
1.18
1.2
1.1
—
—
—
0
0
11
57
1.94
1.17
1.3
1.2
—
—
—
0
0
49
370
1.35
1.16
11.2
7.3
24.84
24.73
mmol/l
0.09
49
370
195
1726
1.18
1.15
4.4
3.3
0.00
0.00
estimate
1.08
72
652
8
39
2.06
1.15
1.4
1.3
—
—
—
0
0
21
134
1.58
1.15
4.4
2.8
54.57
56.43
%
0.32
21
134
5
20
2.51
1.15
4.0
1.8
—
—
—
0
0
49
373
1.34
1.11
1.9
1.6
—
—
—
0
0
7
31
2.27
1.10
1.0
1.1
86.13
203.98
iu/ml
—
7
31
123
1049
1.21
1.10
1.7
1.6
—
—
—
0
0
61
766
0.78
1.10
1.6
1.7
3.32
3.43
mmol/l
0.40
46
522
103
864
1.22
1.09
2.0
2.0
—
—
—
0
0
33
237
1.41
1.06
1.2
1.1
1.23
1.80
u/ml
0.39
19
129
45
342
1.34
1.04
1.4
1.3
—
—
—
0
0
235
2128
1.15
1.03
3.8
2.9
26.61
29.50
u/l
1.41
226
2028
9
47
1.93
1.02
1.1
1.1
105.00
119.15
pmol/l
—
9
47
9
47
1.93
1.02
1.0
1.1
—
—
—
0
0
69
559
1.26
1.01
1.6
1.8
—
—
—
0
0
46
354
1.32
0.99
1.8
1.5
1.29
1.27
mm
0.09
41
259
9
49
1.85
0.99
1.7
3.2
—
—
—
0
0
7
36
1.95
0.97
3.4
3.6
—
—
—
0
0
10
54
1.86
0.97
2.8
2.1
40.18
41.63
%
—
10
54
167
1481
1.17
0.97
3.7
3.2
1.02
1.02
kg/l
0.59
98
976
56
445
1.28
0.96
1.9
1.9
—
—
—
0
0
13
77
1.70
0.95
1.1
1.1
0.27
0.38
u/ml
—
7
25
47
365
1.31
0.95
1.8
1.5
—
—
—
0
0
69
564
1.25
0.94
1.6
1.8
—
—
—
0
0
31
227
1.38
0.92
6.2
2.6
0.56
0.59
%
0.23
31
227
59
476
1.26
0.90
1.3
1.2
—
—
—
0
0
68
558
1.24
0.90
1.6
1.8
—
—
—
0
0
42
325
1.31
0.89
3.7
4.0
5.72
5.38
ug/l
0.05
32
249
43
335
1.30
0.87
4.6
3.1
1.23
1.22
mmol/l
0.23
38
287
30
221
1.37
0.87
1.3
2.6
—
—
—
0
0
17
112
1.53
0.85
1.1
1.1
—
—
—
0
0
6
31
1.94
0.84
2.0
1.5
—
—
—
0
0
29
214
1.37
0.83
3.0
2.2
6.20
4.38
iu/l
0.25
12
94
47
374
1.27
0.82
18.6
5.5
7.97
6.96
mmol/l
0.61
47
359
67
556
1.23
0.82
1.6
1.8
—
—
—
0
0
50
402
1.26
0.81
8.8
7.9
-0.76
0.67
mmol/l
1.71
44
324
87
744
1.19
0.79
2.0
2.8
3.63
4.80
e9/l
1.50
79
675
114
1000
1.17
0.77
1.5
1.6
439.55
36670846.73
pmol/l
1.28
99
889
6
34
1.77
0.76
1.5
2.9
357.67
469.35
u/ml
—
6
34
12
75
1.61
0.75
2.3
2.0
—
—
—
0
0
62
516
1.22
0.75
1.7
1.9
0.00
0.02
estimate
0.50
17
140
5
24
2.09
0.74
1.8
1.5
160.30
169.77
nmol/l
—
5
24
36
281
1.30
0.74
1.3
1.2
0.20
0.83
u/ml
—
5
16
79
676
1.19
0.72
1.2
1.2
—
—
—
0
0
50
409
1.24
0.71
8.9
7.9
7.43
7.42
ph
0.98
22
213
7
40
1.76
0.71
1.1
2.1
—
—
—
0
0
12
77
1.57
0.69
1.3
1.3
—
—
—
0
0
21
153
1.38
0.67
2.4
1.3
51.07
12.54
e6/l
0.48
14
113
13
86
1.52
0.66
1.5
4.5
1.40
2.76
ratio
—
8
43
26
198
1.32
0.65
1.2
1.1
1.96
4.42
u/ml
1.12
16
100
13
87
1.50
0.63
2.1
2.4
75.30
163.51
ug/min
—
8
52
48
398
1.22
0.62
12.0
7.0
1.01
1.21
mmol/l
1.65
48
392
8
49
1.64
0.62
1.0
1.0
—
—
—
0
0
8
49
1.64
0.62
1.1
1.0
—
—
—
0
0
21
156
1.36
0.61
2.5
1.3
5204.81
130.75
e6/l
0.46
16
120
5
30
1.67
0.61
1.4
4.5
—
37.33
—
0
8
8
50
1.61
0.61
1.1
1.3
—
264.29
—
0
7
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
20
148
1.36
0.60
1.1
1.0
16.53
2.09
eliau/ml
—
9
68
6
35
1.72
0.57
3.0
2.2
1.13
1.19
mmol/l
—
6
35
6
35
1.72
0.57
3.0
2.2
105.50
106.00
mmol/l
—
6
35
6
35
1.72
0.57
3.0
2.2
3.58
3.93
mmol/l
—
6
35
77
673
1.16
0.57
1.6
1.5
—
—
—
0
0
30
238
1.27
0.57
1.4
2.0
41.10
40.06
nmol/l
0.10
30
233
8
54
1.49
0.57
2.1
1.5
0.50
0.49
e9/l
—
8
54
58
496
1.18
0.56
4.4
3.1
—
—
—
0
0
8
55
1.46
0.56
1.1
1.1
—
—
—
0
0
10
65
1.55
0.55
3.0
2.9
3.47
13.17
u/ml
—
10
65
6
37
1.63
0.55
1.8
1.5
—
—
—
0
0
52
441
1.19
0.55
1.7
1.8
—
—
—
0
0
18
133
1.36
0.55
1.3
1.2
—
—
—
0
0
609
5972
1.13
0.55
5.2
4.6
2.81
2.82
mmol/l
0.06
589
5715
58
498
1.18
0.54
1.8
2.3
11.56
12.75
nmol/l
0.38
50
473
29
232
1.26
0.53
2.0
2.0
—
—
—
0
0
6
39
1.54
0.53
1.2
1.1
—
—
—
0
0
6
40
1.50
0.51
1.5
1.2
—
—
—
0
0
21
162
1.31
0.50
1.2
1.3
—
—
—
0
0
23
180
1.29
0.50
1.2
1.1
0.02
0.19
u/ml
—
9
60
7
45
1.56
0.49
1.0
1.5
262.86
181.07
pmol/l
—
7
45
44
373
1.19
0.48
1.2
1.1
1.48
1.53
g/l
0.81
44
373
27
217
1.25
0.48
4.0
4.9
23.70
24.32
mmol/l
0.65
27
212
7
46
1.53
0.48
1.1
1.7
3.91
6.54
ug/l
—
7
41
605
5942
1.11
0.48
4.6
4.2
4.67
4.73
mmol/l
0.93
588
5706
16
120
1.34
0.46
2.3
2.3
0.89
0.86
nmol/l
0.04
11
107
23
184
1.26
0.44
1.1
1.3
155.87
139.32
pmol/l
0.05
23
179
602
5918
1.11
0.44
4.5
4.1
1.41
1.48
mmol/l
4.64
585
5655
44
378
1.17
0.43
1.2
1.1
0.84
0.87
g/l
0.51
44
378
58
510
1.15
0.43
1.8
1.6
—
—
—
0
0
40
342
1.18
0.42
10.2
7.9
119.78
124.26
g/l
0.59
40
331
0
15
0.00
0.41
0.0
1.0
—
7.41
—
0
9
0
15
0.00
0.41
0.0
1.4
—
64.07
—
0
15
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
12
88
1.37
0.40
2.7
2.6
—
15.98
—
0
6
20
248
0.80
0.39
2.5
2.2
—
—
—
0
0
14
106
1.33
0.39
4.2
3.0
9.30
24.07
mg/l
—
9
69
0
19
0.00
0.39
0.0
1.0
—
5.55
—
0
19
17
133
1.28
0.39
1.2
1.1
—
—
—
0
0
17
133
1.28
0.39
2.6
1.3
—
—
—
0
0
13
98
1.33
0.37
1.5
4.5
65.51
94.08
mg/l
0.18
13
87
13
98
1.33
0.37
1.5
4.5
24.04
43.87
mg/l
0.45
13
87
10
72
1.39
0.37
1.3
1.3
6.57
15.03
u/l
—
10
63
29
244
1.20
0.37
5.5
4.5
—
—
—
0
0
20
245
0.81
0.36
1.5
1.7
—
—
—
0
0
6
42
1.43
0.35
1.2
1.1
—
—
—
0
0
6
47
1.28
0.32
1.7
6.2
5.48
6.22
mmol/l
—
6
35
14
110
1.28
0.32
1.9
2.0
—
2160.00
—
0
7
28
326
0.85
0.31
1.6
1.6
0.13
0.27
mg/l
1.36
12
148
231
2214
1.06
0.31
1.8
1.7
—
—
—
0
0
45
400
1.13
0.31
1.1
1.1
—
—
—
0
0
7
54
1.30
0.30
1.4
1.5
24.40
27.69
umol/l
—
7
49
10
75
1.34
0.30
1.2
1.2
—
—
—
0
0
11
84
1.31
0.30
4.2
2.7
34.27
33.24
umol/l
0.07
11
76
44
392
1.13
0.29
2.6
2.1
—
—
—
0
0
7
56
1.25
0.29
1.7
1.3
31.43
32.82
pg
—
7
56
7
56
1.25
0.29
2.9
4.1
51.16
110.55
u/ml
—
7
50
270
2795
0.95
0.29
3.0
2.6
—
—
—
0
0
21
176
1.20
0.29
13.3
5.6
1.46
1.18
mg/l
0.80
21
161
19
158
1.21
0.28
1.7
1.3
256.09
330.76
ug/g
0.96
11
90
10
76
1.32
0.28
3.6
1.1
—
—
—
0
0
8
62
1.29
0.28
1.5
1.6
1.38
1.66
mmol/l
—
8
62
8
63
1.27
0.28
1.0
1.1
—
—
—
0
0
8
64
1.25
0.27
1.0
1.4
—
—
nmol/l
—
0
0
8
67
1.20
0.26
1.0
1.1
—
—
—
0
0
13
105
1.24
0.25
3.8
2.5
—
—
—
0
0
9
77
1.17
0.24
1.7
1.6
48.87
34.38
nmol/l
—
9
66
19
161
1.19
0.24
1.6
1.4
32.69
20.07
u/l
0.68
13
137
43
389
1.11
0.24
1.4
1.4
219.19
248.14
miu/ml
0.26
26
209
24
209
1.15
0.23
14.9
9.8
15.33
16.47
%
1.07
24
197
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
23
201
1.15
0.21
1.5
1.4
0.48
0.39
nmol/l
0.31
17
169
16
136
1.18
0.20
2.0
1.6
525.70
342.46
mu/l
—
10
115
561
5560
1.04
0.15
3.9
3.6
1.28
1.23
mmol/l
0.97
539
5285
9
78
1.16
0.15
2.2
1.5
—
—
—
0
0
42
392
1.08
0.14
2.3
3.1
7.31
7.34
ph
0.13
28
285
9
107
0.84
0.13
1.1
1.1
—
—
—
0
0
16
179
0.89
0.12
1.6
1.8
—
—
—
0
0
19
173
1.10
0.10
7.5
7.6
—
—
—
0
0
18
164
1.10
0.10
2.9
3.9
1.47
1.61
%
0.28
18
151
5
47
1.06
0.09
1.0
1.1
1263.80
1407.53
miu/ml
—
5
47
29
272
1.07
0.09
1.7
1.9
0.10
2.28
estimate
—
10
110
5
63
0.79
0.08
1.2
1.6
—
—
—
0
0
8
74
1.08
0.07
2.1
1.1
—
—
—
0
0
96
939
1.03
0.06
4.0
4.2
1.65
1.67
ug/l
0.04
89
853
21
200
1.05
0.03
1.1
1.1
—
—
—
0
0
21
200
1.05
0.03
1.1
1.1
—
—
—
0
0
15
142
1.06
0.02
3.0
4.2
0.86
0.91
%
0.31
15
127
93
919
1.01
0.02
1.3
1.3
—
—
—
0
0
21
205
1.03
0.00
3.4
6.1
23.32
24.31
mmol/l
0.55
21
192
18
179
1.01
0.00
2.0
4.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
590.06
—
0
5
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
81
0.99
-0.00
1.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.4
—
6.37
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
57
570
1.00
-0.00
3.1
2.6
0.53
0.69
ug/l
1.44
35
300
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
3.00
—
0
9
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_WHOOPCOUGH_WIDE – Whooping cough, including avohilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).