Clubfoot

Q17_CLUBFOOT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q66.0
  • Hospital discharge: ICD-9 7546A
  • Hospital discharge: ICD-8 75400|75401
  • Cause of death: ICD-10 Q66.0
  • Cause of death: ICD-8 75400|75401

2 out of 7 registries used, show all original rules.

407

4. Check minimum number of events

None

407

5. Include endpoints

None

407

6. Filter based on genotype QC (FinnGen only)

378

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 378 211 167
Unadjusted period prevalence (%) 0.08 0.07 0.08
Median age at first event (years) 9.28 9.36 9.18

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
389
Matched controls
3890
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q66.0
ICD-10 Finland
Talipes equinovarus
+∞
287.5
239
*
75400
ICD-8 Finland
Clubfoot (congenital), Pes equino-varus adductus
+∞
132.0
119
*
75401
ICD-8 Finland
Clubfoot (congenital), Metatarsus varus
+∞
73.3
68
*
7545B
ICD-9 Finland
Certain congenital musculoskeletal deformities, Varus deformities of feet[TALIPES EQUINOVARUS CONGENITUS]
+∞
50.1
47
*
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
16.3
37.8
33
22
9341
FHL
Reduction and plaster or plaster exchange
+∞
36.0
34
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.8
29.1
74
180
SPAT1229
SPAT
Assessment of need for aid
7.2
27.4
43
66
TNH36
NOMESCO Finland
Custom molded cast of pes equinovarus
+∞
27.4
26
*
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
6.5
27.4
48
83
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
7.7
25.9
38
54
9343
FHL
Posterior release or posteromedical release
+∞
25.3
24
*
NH1AD
NOMESCO Finland
Ankle and foot CT
9.1
25.2
32
38
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
75.1
25.1
28
*
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
4.4
22.2
62
161
NHG22
NOMESCO Finland
Fusion of subtalar joint
85.1
21.9
24
*
M21.5
ICD-10 Finland
Acquired clawhand, clubhand, clawfoot and clubfoot
53.2
21.4
25
5
NHT62
NOMESCO Finland
Surgical procedure for correction of pes equinovarus
+∞
20.0
19
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
6.8
19.1
31
49
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
+∞
17.8
17
*
Q66.8
ICD-10 Finland
Other congenital deformities of feet
99.7
17.7
19
*
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
20.5
17.1
25
13
L82
ICPC
Congenital anomaly musculoskeletal
+∞
16.8
16
*
Q66.9
ICD-10 Finland
Congenital deformity of feet, unspecified
94.2
16.7
18
*
L28
ICPC
Limited function/disability (L)
3.1
16.2
77
284
9111
FHL
Plastering under anesthesia
35.0
15.9
20
6
A46
ICD-10 Finland
Erysipelas
3.2
15.3
69
246
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
15.2
14.2
23
16
9165
FHL
Removal of osteosynthesis material
10.7
14.2
27
27
TNH33
NOMESCO Finland
Custom moulded brace, ankle or foot
12.1
13.5
24
21
Q66.7
ICD-10 Finland
Pes cavus
41.6
13.2
16
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.2
12.7
22
37
R4110
NOMESCO Finland
Physiotherapy
2.3
12.7
125
657
TQW40
NOMESCO Finland
Remowal of suture of skin
3.7
12.6
43
128
M19.2
ICD-10 Finland
Other secondary arthrosis
13.0
12.3
21
17
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
4.2
11.7
32
81
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
23.8
11.7
16
7
L17
ICPC
Foot/toe symptom/complaint
2.2
11.6
138
780
7545A
ICD-9 Finland
Certain congenital musculoskeletal deformities, Varus deformities of feet[TALIPES VARUS CONGENITUS]
+∞
11.5
11
*
7546A
ICD-9 Finland
Certain congenital musculoskeletal deformities, Valgus deformities of feet[TALIPES VALGUS CONGENITUS]
+∞
11.5
11
*
Q66.6
ICD-10 Finland
Other congenital valgus deformities of feet
+∞
11.5
11
*
G60.0
ICD-10 Finland
Hereditary motor and sensory neuropathy
36.2
11.3
14
*
Z3226
NOMESCO Finland
Physiotherapist
2.4
11.2
89
423
TNX99
NOMESCO Finland
Other orthopaedic minor procedure
5.5
11.2
22
42
B01AB05
ATC
enoxaparin; parenteral
2.3
11.1
112
590
NHG20
NOMESCO Finland
Fusion of talocrural joint
44.7
11.0
13
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
10.8
142
831
R5110, ,
SPAT
3.5
10.3
37
114
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
4.8
10.1
23
50
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
56.4
9.7
11
*
NHL20
NOMESCO Finland
Myotomy or tenotomy of foot
30.9
9.5
12
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.6
9.4
58
243
L84
ICD-10 Finland
Corns and callosities
4.7
9.4
22
49
9115
FHL
Epiphysiodesis (in hip luxation trokanter 9408)
+∞
9.4
9
*
9344
FHL
Other operation on soft tissue of the foot
+∞
9.4
9
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
9.4
42
148
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
5.0
9.2
20
42
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
3.6
9.1
31
92
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
7.2
8.7
20
29
ZXA00
NOMESCO Finland
Right side
2.2
8.6
89
469
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
8.6
144
905
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
+∞
8.4
8
*
9359
FHL
Other measure in this category
+∞
8.4
8
*
A28
ICPC
Limited function/disability NOS
2.6
8.1
48
197
S97
ICPC
Chronic ulcer skin
3.4
8.1
29
89
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.5
7.9
51
218
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
7.9
109
638
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
7.2
7.9
18
26
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
11.1
7.9
14
13
TNH31
NOMESCO Finland
Prefabricated orthosis, ankle or foot
9.7
7.8
15
16
Z50.1
ICD-10 Finland
Other physical therapy
3.7
7.8
25
71
Q66.2
ICD-10 Finland
Metatarsus varus
45.9
7.7
9
*
ZXA05
NOMESCO Finland
Left side
2.1
7.7
80
421
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
7.4
46
193
Q66.4
ICD-10 Finland
Talipes calcaneovalgus
+∞
7.3
7
*
75409
ICD-8 Finland
Clubfoot (congenital), Unspecified
+∞
7.3
7
*
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
4.4
7.3
18
42
ZXE00
NOMESCO Finland
One hour or less
1.8
7.2
156
1051
WX213
NOMESCO Finland
Lower leg blockade
20.5
7.2
10
5
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
6.0
7.0
18
31
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
6.9
52
239
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
6.9
54
253
XKC03
NOMESCO Finland
Water cystometry
5.7
6.7
18
33
7410D
ICD-9 Finland
Spina bifida, With hydrocephalus[SPINA BIFIDA APERTA CUM HYDROCEPHALO REG LUMBALIS]
71.0
6.4
7
*
M41.4
ICD-10 Finland
Neuromuscular scoliosis
71.0
6.4
7
*
9342
FHL
Akillestenotomy
71.0
6.4
7
*
Z31.5
ICD-10 Finland
Genetic counselling
2.6
6.3
37
151
ZXA10
NOMESCO Finland
Bilateral
2.1
6.3
66
348
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
+∞
6.3
6
*
Q05.9
ICD-10 Finland
Spina bifida, unspecified
+∞
6.3
6
*
9345
FHL
Tendon or tendon transplantation
+∞
6.3
6
*
NGL66
NOMESCO Finland
Transposition of tendon of knee or lower leg
27.1
6.2
8
*
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
27.1
6.2
8
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
145
983
1.76
6.39
4.2
3.2
50.86
122.28
e6/l
0.45
115
741
163
1168
1.68
5.73
4.9
3.9
45.82
52.56
e6/l
0.13
121
793
125
856
1.68
5.10
3.8
3.2
0.27
0.33
e6/l
0.29
94
620
79
482
1.80
4.83
3.5
3.1
5.02
2.07
e6/l
1.23
37
223
101
662
1.71
4.82
3.4
2.6
4.75
7.47
e6/l
1.16
93
602
92
589
1.74
4.77
3.4
2.6
544.15
551.21
mosm/kgh2o
0.09
82
520
50
263
2.03
4.76
11.8
8.9
8.21
7.76
mmol/l
0.20
50
252
70
422
1.80
4.44
2.9
2.1
—
—
—
0
0
108
741
1.63
4.28
4.5
3.4
—
0.00
—
0
6
113
787
1.61
4.20
4.0
2.4
—
—
—
0
0
168
1294
1.53
3.98
8.1
7.7
1.21
1.22
mmol/l
0.52
159
1209
106
743
1.59
3.80
5.4
4.3
—
—
—
0
0
62
380
1.75
3.71
2.7
1.7
—
—
—
0
0
61
374
1.75
3.64
10.9
9.0
104.70
104.33
mmol/l
0.25
61
374
214
1770
1.46
3.39
6.1
5.6
6.34
6.48
mmol/l
0.46
203
1652
47
276
1.80
3.25
11.8
11.0
1.27
0.83
mmol/l
0.26
39
234
233
1973
1.45
3.17
8.9
10.6
3.88
3.93
e9/l
0.12
197
1726
103
746
1.52
3.13
2.8
2.0
0.92
1.16
mg/l
0.57
82
571
47
280
1.77
3.10
12.0
11.0
7.42
7.42
ph
0.02
19
146
210
1752
1.43
3.05
5.1
3.4
0.00
0.00
estimate
-0.00
50
347
184
1500
1.43
3.03
3.0
2.7
—
—
estimate
—
0
0
43
252
1.79
3.00
12.3
12.4
24.81
24.90
mmol/l
0.06
43
252
48
291
1.74
2.99
11.0
10.3
—
—
—
0
0
359
3363
1.88
2.84
18.3
12.8
22.91
21.06
mg/l
0.52
298
2661
118
900
1.45
2.74
5.6
3.3
0.00
0.00
estimate
0.50
45
359
201
1685
1.40
2.73
6.7
7.1
56.86
56.26
%
0.36
196
1628
176
1443
1.40
2.72
9.8
7.9
1.21
1.21
mmol/l
0.53
157
1279
253
2208
1.42
2.71
5.9
4.1
—
3.17
—
0
6
207
1746
1.40
2.70
5.1
3.3
0.00
0.00
estimate
-0.00
50
372
129
1005
1.42
2.66
6.7
6.4
—
—
—
0
0
195
1636
1.38
2.59
6.8
7.3
2.89
2.83
%
0.14
189
1557
15
63
2.44
2.49
3.2
3.0
—
—
—
0
0
147
1183
1.39
2.48
16.8
9.3
1.19
1.13
inr
0.68
123
962
194
1634
1.37
2.48
6.9
7.4
0.65
0.68
%
0.43
188
1552
194
1638
1.37
2.42
7.1
7.4
8.38
8.47
%
0.21
189
1566
49
320
1.61
2.34
2.9
7.1
7.36
7.38
ph
0.72
29
183
203
1735
1.36
2.31
5.1
3.3
0.00
0.00
estimate
-0.00
49
377
200
1706
1.35
2.30
7.1
7.2
29.33
29.45
%
0.06
194
1644
214
1846
1.35
2.28
6.6
7.1
1.94
1.98
e9/l
0.28
194
1652
7
18
3.94
2.26
3.3
2.9
—
—
—
0
0
130
1039
1.38
2.25
2.5
2.3
—
—
—
0
0
26
143
1.88
2.25
2.4
2.2
—
—
—
0
0
171
1430
1.35
2.21
4.0
3.1
6.18
6.18
ph
0.01
91
837
18
87
2.12
2.20
1.4
2.9
3.76
2.28
index
—
8
50
207
1783
1.34
2.20
6.7
7.2
0.54
0.55
e9/l
0.09
184
1559
207
1787
1.34
2.14
6.8
7.1
0.04
0.04
e9/l
0.27
184
1560
59
411
1.51
2.14
3.1
2.7
31.13
29.69
s
0.91
59
403
184
1569
1.33
2.04
10.8
10.9
0.00
0.00
e9/l
0.64
151
1274
140
1149
1.34
2.01
6.9
7.2
—
—
—
0
0
47
318
1.54
1.95
3.0
2.4
31.89
36.42
u/l
0.38
38
263
107
847
1.36
1.94
2.4
2.2
253.66
299.38
u/l
0.18
102
813
106
841
1.36
1.89
4.0
3.9
7.39
7.39
ph
0.59
73
595
36
236
1.58
1.72
2.8
3.4
4.54
4.76
pmol/l
0.65
31
208
210
1854
1.29
1.70
7.0
7.6
0.19
0.19
e9/l
0.26
190
1645
38
254
1.55
1.68
2.8
2.0
6.16
6.18
ph
0.04
22
162
10
40
2.54
1.67
1.6
1.2
—
—
—
0
0
7
25
2.83
1.65
1.6
1.6
33.00
32.68
pg
—
7
25
35
235
1.54
1.53
14.9
11.3
118.66
124.45
g/l
0.78
35
228
6
21
2.89
1.51
1.3
1.5
14.83
9.96
umol/l
—
6
21
9
38
2.40
1.46
2.2
5.0
—
—
—
0
0
261
2396
1.27
1.42
8.5
7.7
79.08
78.64
u/l
0.06
255
2286
36
248
1.50
1.41
4.3
5.0
5.14
5.09
kpa
0.15
36
238
6
23
2.63
1.37
2.2
1.5
0.68
1.10
%
—
6
13
36
504
0.69
1.36
1.1
1.4
—
—
—
0
0
130
1106
1.26
1.35
1.6
1.6
—
—
—
0
0
0
39
0.00
1.34
0.0
1.5
—
191.88
—
0
39
66
513
1.35
1.34
3.3
3.4
398.67
411.70
ng/l
0.02
43
330
144
1244
1.25
1.31
5.4
5.4
36.30
37.26
g/l
1.27
133
1185
181
1606
1.24
1.29
6.4
6.6
11.00
10.91
umol/l
0.04
158
1534
63
491
1.34
1.26
2.5
2.6
2.43
2.42
mmol/l
0.27
54
435
6
25
2.42
1.25
2.2
1.9
—
—
—
0
0
151
1318
1.24
1.24
5.2
3.0
0.00
0.00
estimate
0.50
40
316
116
983
1.26
1.24
2.9
3.2
2.34
2.36
mmol/l
1.39
108
906
23
148
1.59
1.23
2.3
7.5
0.73
0.59
%
1.30
23
148
7
144
0.48
1.23
1.7
1.5
—
—
—
0
0
13
71
1.86
1.21
1.0
1.1
—
—
—
0
0
8
39
2.07
1.16
15.4
2.2
—
—
—
0
0
5
20
2.52
1.15
1.8
1.3
47.40
51.13
%
—
5
15
114
973
1.24
1.14
3.9
2.6
64.58
67.76
u/l
0.09
104
915
12
66
1.84
1.10
1.2
1.3
2.43
5.00
u/ml
—
7
30
27
186
1.49
1.09
1.7
1.7
7.33
8.45
u/l
0.20
22
150
94
789
1.25
1.09
5.4
3.1
1.02
1.02
kg/l
0.87
62
516
8
148
0.53
1.06
1.8
1.6
—
—
—
0
0
11
60
1.86
1.04
5.8
5.8
437.55
377.30
umol/l
1.18
11
53
5
108
0.46
1.02
1.0
1.1
—
—
—
0
0
38
284
1.37
1.01
2.7
2.0
0.00
0.04
estimate
—
9
74
9
48
1.90
1.01
1.1
1.3
—
—
—
0
0
11
61
1.83
0.99
2.3
2.7
3.37
2.71
mmol/l
—
6
40
11
61
1.83
0.99
2.3
2.7
5.13
5.00
kpa
0.33
11
61
11
61
1.83
0.99
2.3
2.7
9.46
8.69
kpa
0.76
11
61
279
2631
1.21
0.95
4.5
4.3
14.62
14.51
pmol/l
0.32
266
2454
306
3187
0.81
0.89
4.8
4.3
1.39
1.43
mmol/l
1.28
295
3025
61
499
1.26
0.88
1.5
1.6
413.34
25714721.36
pmol/l
0.50
53
455
8
43
1.88
0.88
2.6
1.8
1.80
1.75
mmol/l
—
8
43
19
128
1.51
0.87
4.6
8.4
—
—
—
0
0
13
202
0.63
0.85
1.0
1.1
—
—
—
0
0
14
89
1.59
0.82
3.1
2.8
7.40
7.41
ph
1.24
14
89
133
1479
0.85
0.82
2.5
2.7
—
—
—
0
0
134
1200
1.18
0.79
1.8
1.9
100.85
96.81
pmol/l
0.50
61
619
0
25
0.00
0.79
0.0
1.1
—
1502.04
—
0
25
8
48
1.68
0.79
2.3
2.3
—
—
—
0
0
93
807
1.20
0.79
4.8
4.3
12.04
9.87
mg/mmol
0.13
68
539
0
26
0.00
0.78
0.0
6.4
—
8.00
—
0
26
0
26
0.00
0.78
0.0
3.2
—
40.38
—
0
26
19
132
1.46
0.77
1.6
1.6
—
12.08
—
0
5
6
34
1.78
0.76
2.3
1.1
—
—
—
0
0
359
3501
1.33
0.76
12.1
10.5
29.42
27.84
u/l
0.53
354
3427
17
116
1.49
0.75
1.8
1.4
—
—
—
0
0
5
24
2.10
0.75
1.0
1.2
—
—
—
0
0
158
1441
1.16
0.74
2.8
2.7
76.56
73.09
nmol/l
0.85
147
1348
6
108
0.55
0.73
1.0
1.1
—
—
—
0
0
32
247
1.32
0.73
2.4
2.5
5985.55
5485.83
u/l
—
8
108
21
151
1.41
0.73
7.7
3.7
—
—
—
0
0
9
56
1.62
0.73
1.3
1.2
—
—
—
0
0
7
39
1.81
0.73
1.7
1.1
—
—
—
0
0
16
109
1.49
0.72
2.6
6.3
570.11
245.80
mg/l
—
9
56
61
514
1.22
0.70
1.4
1.4
451.43
530.00
titre
—
7
112
20
144
1.41
0.69
3.3
3.2
20.20
21.37
s
0.90
20
131
28
215
1.33
0.67
1.1
1.2
—
—
—
0
0
30
234
1.31
0.65
1.5
1.7
—
—
—
0
0
53
444
1.22
0.65
3.4
2.5
2.39
2.38
g/l
0.06
47
415
5
29
1.73
0.64
1.2
1.2
—
—
—
0
0
30
236
1.29
0.62
6.3
3.8
—
—
—
0
0
5
30
1.68
0.61
1.2
1.2
—
—
—
0
0
12
80
1.52
0.60
1.2
2.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
312
3215
0.85
0.59
5.4
4.7
2.79
2.82
mmol/l
0.23
303
3057
6
35
1.73
0.58
7.0
6.0
6.77
6.81
mmol/l
—
6
29
34
276
1.25
0.56
2.6
4.0
1.76
1.71
%
0.08
29
257
20
151
1.34
0.55
1.2
1.3
—
3.10
—
0
9
33
270
1.24
0.52
3.5
6.0
0.90
0.83
%
—
10
86
25
199
1.27
0.49
1.3
1.2
—
—
—
0
0
113
1037
1.13
0.47
3.2
3.1
57.86
43.87
ng/l
0.13
71
588
33
274
1.22
0.46
5.0
3.3
—
—
—
0
0
82
738
1.14
0.46
4.4
4.3
1.57
1.57
ug/l
0.00
70
662
7
49
1.44
0.46
1.1
1.4
—
67.54
—
0
5
14
103
1.37
0.46
4.1
9.2
2.40
1.56
%
0.43
14
93
110
1011
1.12
0.45
4.1
3.8
8.46
8.68
mmol/l
0.19
101
887
31
257
1.22
0.44
3.3
5.8
0.67
0.57
%
—
9
76
10
69
1.46
0.44
2.1
2.7
—
—
—
0
0
355
3488
1.20
0.44
15.8
11.0
—
—
—
0
0
184
1742
1.11
0.43
3.2
3.2
85.82
95.74
ug/l
0.49
173
1662
11
78
1.42
0.43
1.4
1.1
—
—
—
0
0
8
56
1.44
0.43
1.4
1.6
—
—
—
0
0
8
56
1.44
0.43
1.4
1.6
—
—
—
0
0
8
56
1.44
0.43
1.4
1.6
—
—
—
0
0
8
56
1.44
0.43
1.4
1.6
—
—
—
0
0
5
32
1.57
0.42
1.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
44
382
1.17
0.40
4.1
2.5
13.26
14.06
nmol/l
0.29
37
363
0
18
0.00
0.40
0.0
9.6
—
6.93
—
0
18
0
19
0.00
0.39
0.0
6.2
—
45.38
—
0
5
111
1029
1.11
0.39
4.4
2.6
0.00
0.00
estimate
-0.00
45
296
16
203
0.78
0.39
1.1
1.1
0.90
0.92
g/l
0.09
16
203
19
235
0.80
0.38
1.3
1.4
—
—
—
0
0
17
134
1.28
0.37
1.2
1.5
1.10
1.19
g/l
0.66
17
128
5
37
1.36
0.37
2.4
2.6
42.70
37.45
%
—
5
37
33
282
1.19
0.37
1.8
1.5
22.66
20.70
iu/l
0.11
27
237
11
81
1.37
0.36
3.2
11.6
64.28
63.42
%
0.05
11
81
314
3069
1.12
0.36
5.6
5.1
1.78
1.80
mu/l
0.16
307
2903
6
41
1.47
0.36
1.0
1.3
—
—
—
0
0
6
42
1.44
0.35
1.0
1.2
—
—
—
0
0
30
256
1.19
0.34
3.6
6.2
0.14
0.11
%
—
7
71
87
802
1.11
0.34
3.8
3.6
44.54
62.85
mg/l
0.41
64
552
6
46
1.31
0.33
1.3
2.5
—
—
—
0
0
85
785
1.11
0.32
2.5
2.3
2.60
2.62
mg/l
0.04
77
686
6
47
1.28
0.32
1.3
1.6
18.50
30.74
ng/l
—
6
47
6
47
1.28
0.32
1.2
1.2
11.45
14.52
u/l
—
6
42
27
315
0.85
0.32
1.3
1.3
119.35
151.78
u/ml
0.17
11
123
16
197
0.80
0.32
1.1
1.1
—
0.68
—
0
15
17
207
0.81
0.31
1.2
1.5
—
—
—
0
0
10
75
1.34
0.30
1.0
1.1
—
—
—
0
0
31
269
1.17
0.30
5.5
2.6
—
—
—
0
0
8
109
0.73
0.29
1.3
1.2
—
—
—
0
0
45
404
1.13
0.28
1.6
1.6
—
—
—
0
0
64
696
0.90
0.28
1.6
1.6
—
—
—
0
0
12
94
1.29
0.28
1.7
1.9
48.56
0.72
ug/l
0.54
12
87
10
76
1.32
0.28
1.9
1.9
—
—
—
0
0
16
193
0.82
0.27
1.2
1.3
253.20
250.50
miu/ml
—
5
96
70
650
1.09
0.25
1.3
1.3
37.47
26.50
iu/ml
0.28
19
184
45
408
1.12
0.25
1.6
1.8
—
—
—
0
0
296
3015
0.92
0.25
4.0
3.7
1.27
1.28
mmol/l
0.09
282
2850
23
199
1.17
0.24
2.4
3.8
77.52
71.49
e9/l
0.18
18
139
311
3058
1.08
0.23
21.8
16.2
333.34
334.15
g/l
0.88
311
3042
315
3199
0.92
0.23
4.7
4.4
4.59
4.70
mmol/l
1.28
303
3054
17
200
0.84
0.23
1.1
1.1
1.50
1.50
g/l
0.03
17
200
95
898
1.08
0.23
1.6
1.5
1.81
2.15
g/l
1.85
57
564
14
116
1.21
0.22
1.1
1.3
—
2.97
—
0
15
5
41
1.22
0.22
1.6
3.5
—
—
—
0
0
5
42
1.19
0.21
4.6
18.3
11.74
11.31
%
—
5
42
36
397
0.90
0.21
1.3
1.7
3.59
3.52
mmol/l
0.11
26
276
0
11
0.00
0.21
0.0
3.2
—
0.61
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
9.08
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
110
1049
1.07
0.21
2.1
2.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
290.63
—
0
8
27
240
1.13
0.20
1.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
77.99
—
0
14
0
14
0.00
0.20
0.0
1.7
—
2156.79
—
0
14
11
90
1.23
0.19
4.2
10.2
0.72
0.89
%
0.79
11
81
246
2510
0.95
0.18
3.3
3.3
36.98
40.40
u/l
0.59
232
2420
15
128
1.18
0.18
2.5
1.7
—
—
—
0
0
63
592
1.08
0.18
1.3
1.3
4.46
6.81
u/ml
0.28
21
235
7
60
1.17
0.18
6.6
3.1
13.11
7.14
pmol/l
—
7
60
24
215
1.12
0.17
1.7
1.6
0.19
0.27
mg/l
—
10
93
18
159
1.14
0.15
2.3
2.0
0.00
0.02
estimate
—
7
60
10
118
0.84
0.14
1.2
1.3
—
—
—
0
0
303
2994
1.05
0.14
4.9
4.1
5.80
5.75
mmol/l
0.27
291
2809
12
138
0.87
0.13
1.0
1.2
—
—
—
0
0
374
3722
1.13
0.12
26.1
19.8
254.80
255.69
e9/l
0.10
369
3666
34
319
1.07
0.10
3.9
2.5
—
—
—
0
0
11
96
1.15
0.10
10.3
11.6
—
—
—
0
0
5
45
1.11
0.10
4.6
16.7
12.60
11.08
mmol/l
—
5
38
5
45
1.11
0.10
4.6
16.7
105.00
105.55
mmol/l
—
5
38
59
567
1.05
0.09
1.8
1.7
—
—
—
0
0
20
184
1.09
0.09
4.6
5.4
—
—
—
0
0
374
3725
1.10
0.09
26.0
19.7
4.62
4.62
e12/l
0.06
369
3662
67
647
1.04
0.09
2.1
1.9
—
—
—
0
0
6
57
1.05
0.08
3.2
3.2
—
—
—
0
0
123
1256
0.97
0.08
1.9
2.0
—
—
—
0
0
80
777
1.04
0.08
1.5
1.5
19.65
21.26
nmol/l
0.51
74
675
6
73
0.82
0.07
1.0
1.1
—
—
—
0
0
32
337
0.95
0.07
5.7
2.4
—
—
—
0
0
7
81
0.86
0.07
1.7
1.3
—
—
—
0
0
8
95
0.84
0.06
1.0
1.2
—
94.17
—
0
12
12
109
1.10
0.06
2.2
1.9
2.14
5.41
iu/l
—
5
44
374
3728
1.08
0.06
26.1
19.8
6.79
6.65
e9/l
0.71
369
3661
133
1351
0.98
0.06
1.9
1.9
1.50
1.39
mmol/l
0.60
120
1199
12
131
0.91
0.05
1.3
1.2
—
—
—
0
0
25
238
1.05
0.05
4.5
4.0
7.25
7.34
ph
0.54
20
177
86
844
1.02
0.04
3.9
5.1
—
—
—
0
0
38
368
1.04
0.04
1.6
1.5
974.50
1160.12
nmol/l
0.65
26
284
54
553
0.97
0.04
1.5
2.7
107.48
100.25
ug/g
0.10
47
439
12
129
0.93
0.03
2.4
2.2
—
—
—
0
0
14
131
1.07
0.03
1.1
1.2
—
—
—
0
0
10
108
0.92
0.03
1.0
1.1
0.13
0.78
u/ml
—
5
53
23
221
1.04
0.03
2.6
5.1
51.42
6.72
ug/l
0.45
18
176
41
401
1.03
0.02
1.3
1.2
—
—
—
0
0
85
842
1.01
0.01
1.6
1.8
—
—
—
0
0
33
337
0.98
0.01
5.6
2.5
—
—
—
0
0
33
337
0.98
0.01
5.7
2.4
—
—
—
0
0
36
367
0.98
0.01
1.2
1.4
—
—
—
0
0
39
383
1.02
0.01
1.5
1.6
—
—
—
0
0
40
407
0.98
0.01
1.2
1.2
—
—
—
0
0
10
98
1.02
0.00
1.3
1.5
—
—
—
0
0
292
2919
1.00
0.00
6.8
5.1
37.62
37.86
mmol/mol
0.16
281
2793
19
187
1.02
0.00
2.0
1.9
—
—
—
0
0
36
363
0.99
0.00
1.2
1.2
—
—
—
0
0
46
457
1.01
0.00
3.0
2.7
0.82
0.70
ug/l
0.14
26
240
38
385
0.99
0.00
1.6
1.5
—
—
—
0
0
34
336
1.01
0.00
5.5
2.5
—
—
—
0
0
5
49
1.02
0.00
1.0
2.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
6.0
—
1.03
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
26.3
—
0.46
—
0
7
9
92
0.98
-0.00
1.1
1.9
3.91
3.56
mmol/l
—
9
86
100
1000
1.00
-0.00
1.3
1.4
0.50
1.36
u/ml
2.46
23
269
0
7
0.00
-0.00
0.0
7.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
5.67
—
0
9
0
9
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.82
—
0
5
6
68
0.88
-0.00
1.0
1.1
—
106.16
—
0
19
0
7
0.00
-0.00
0.0
2.7
—
1.18
—
0
7
0
5
0.00
-0.00
0.0
4.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_CLUBFOOT – Clubfoot

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).