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Neurofibromatosis, type 2

Endpoint Browser PheWeb

Q17_NEUROFIBROMATOSIS_2

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q85.01
  • Cause of death: ICD-10 — Q85.01

2 out of 7 registries used, show all original rules.

68

4. Check minimum number of events

None

68

5. Include endpoints

None

68

6. Filter based on genotype QC (FinnGen only)

64

Control definitions (FinnGen only)

Control exclude
Q17_OTHER_CONGEN_MALFO

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: unknown.

No upset table: unknown.

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 64 39 25
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 44.63 42.75 47.55

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
68
Matched controls
680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q8501, ,
ICD-10 Finland
Neurofibromatosis, type 2
+∞
97.7
68
*
A98, ,
ICD-O-3
+∞
92.3
66
*
M01AE01, ,
ATC
ibuprofen; systemic, rectal
+∞
74.1
57
*
N02BE01, ,
ATC
paracetamol; systemic, rectal
+∞
74.1
57
*
WX110, ,
ICD-O-3
+∞
72.3
56
*
J01DB01, ,
ATC
cefalexin; oral
+∞
70.6
55
*
J01CA04, ,
ATC
amoxicillin; systemic
+∞
67.2
53
*
SAA02, ,
ICD-O-3
+∞
57.7
47
*
SAA01, ,
ICD-O-3
+∞
54.8
45
*
Q8500, ,
ICD-10 Finland
Neurofibromatosis, type 1
+∞
53.3
44
*
J01CE02, ,
ATC
phenoxymethylpenicillin; oral
+∞
51.8
43
*
S18, ,
ICD-O-3
+∞
50.4
42
*
ZXE10, ,
ICD-O-3
+∞
46.2
39
*
K021, ,
ICD-O-3
+∞
46.2
39
*
A02BC02, ,
ATC
pantoprazole; systemic
+∞
46.2
39
*
EB1AA, ,
ICD-O-3
+∞
44.8
38
*
ZXD10, ,
ICD-O-3
+∞
44.8
38
*
J01AA02, ,
ATC
doxycycline; systemic
+∞
44.8
38
*
J01FA10, ,
ATC
azithromycin; systemic
+∞
43.5
37
*
J01DA01, ,
ATC
[U] cefalexin
+∞
40.8
35
*
AA1CG, ,
ICD-O-3
+∞
39.5
34
*
M01AE02, ,
ATC
naproxen; oral, rectal
+∞
38.1
33
*
Q8509, ,
ICD-10 Finland
Unspecified neurofibromatosis
+∞
38.1
33
*
WZC00, ,
ICD-O-3
+∞
38.1
33
*
SFA20, ,
ICD-O-3
+∞
38.1
33
*
GD1AA, ,
ICD-O-3
+∞
38.1
33
*
R4110, ,
ICD-O-3
+∞
36.8
32
*
SAA03, ,
ICD-O-3
+∞
36.8
32
*
EB1HA, ,
ICD-O-3
+∞
35.6
31
*
J069, ,
ICD-O-3
+∞
35.6
31
*
EB1SA, ,
ICD-O-3
+∞
35.6
31
*
SPAT1249, ,
ICD-O-3
+∞
34.3
30
*
WX408, ,
ICD-O-3
+∞
34.3
30
*
ZXA05, ,
ICD-O-3
+∞
34.3
30
*
J01CR02, ,
ATC
amoxicillin and beta-lactamase inhibitor; systemic
+∞
33.0
29
*
WX290, ,
ICD-O-3
+∞
33.0
29
*
M01AB05, ,
ATC
diclofenac; systemic, rectal
+∞
33.0
29
*
SFA10, ,
ICD-O-3
+∞
31.8
28
*
N02AX02, ,
ATC
tramadol; systemic, rectal
+∞
31.8
28
*
R03AC02, ,
ATC
salbutamol; inhalant
+∞
31.8
28
*
Z010, ,
ICD-10 Finland
Examination of eyes and vision
+∞
31.8
28
*
ZXE00, ,
ICD-O-3
+∞
31.8
28
*
Z3231, ,
ICD-O-3
+∞
30.5
27
*
M03BX02, ,
ATC
tizanidine; oral
+∞
30.5
27
*
Z871, ,
ICD-O-3
+∞
29.3
26
*
D3330, ,
ICD-10 Finland
Acoustic neuroma
+∞
29.3
26
*
R06AE07, ,
ATC
cetirizine; oral
+∞
29.3
26
*
SFA30, ,
ICD-O-3
+∞
29.3
26
*
WYA05, ,
ICD-O-3
+∞
29.3
26
*
N02AJ06, ,
ATC
codeine and paracetamol; systemic
+∞
29.3
26
*
Z012, ,
ICD-O-3
+∞
28.1
25
*
Z011, ,
ICD-10 Finland
Examination of ears and hearing
+∞
28.1
25
*
D82, ,
ICD-O-3
+∞
26.8
24
*
SDA03, ,
ICD-O-3
+∞
26.8
24
*
M01AH05, ,
ATC
etoricoxib; oral
+∞
26.8
24
*
J01CA08, ,
ATC
pivmecillinam; oral
+∞
26.8
24
*
QAE10, ,
ICD-O-3
+∞
26.8
24
*
Q851, ,
ICD-10 Finland
Tuberous sclerosis
+∞
25.6
23
*
C07AB07, ,
ATC
bisoprolol; oral
+∞
25.6
23
*
WX404, ,
ICD-O-3
+∞
25.6
23
*
H903, ,
ICD-10 Finland
Sensorineural hearing loss, bilateral
+∞
25.6
23
*
R01AD09, ,
ATC
mometasone; nasal
+∞
25.6
23
*
ZXA10, ,
ICD-O-3
+∞
24.4
22
*
S01XA20, ,
ATC
artificial tears and other indifferent preparations; ophthalmic
+∞
24.4
22
*
Z315, ,
ICD-10 Finland
Genetic counselling
+∞
24.4
22
*
KMAK, ,
ICD-O-3
+∞
24.4
22
*
ZXA00, ,
ICD-O-3
+∞
24.4
22
*
C10AA05, ,
ATC
atorvastatin; oral
+∞
24.4
22
*
N03AX16, ,
ATC
[U] pregabalin
+∞
24.4
22
*
H02AB06, ,
ATC
prednisolone; systemic
+∞
24.4
22
*
EBA00, ,
ICD-O-3
+∞
23.2
21
*
WZB00, ,
ICD-O-3
+∞
23.2
21
*
-1, ,
ICD-O-3
+∞
23.2
21
*
SPAT1301, ,
ICD-O-3
+∞
23.2
21
*
WX402, ,
ICD-O-3
+∞
23.2
21
*
E0000UV, ,
ATC
+∞
23.2
21
*
J01FA06, ,
ATC
roxithromycin; oral
+∞
22.1
20
*
SPAT1153, ,
ICD-O-3
+∞
22.1
20
*
XCW99, ,
ICD-O-3
+∞
22.1
20
*
AA1AD, ,
ICD-O-3
+∞
22.1
20
*
C10AA01, ,
ATC
simvastatin; oral
+∞
22.1
20
*
WX002, ,
ICD-O-3
+∞
22.1
20
*
SCA01, ,
ICD-O-3
+∞
22.1
20
*
G03CA03, ,
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
+∞
22.1
20
*
I10, ,
ICD-O-3
+∞
22.1
20
*
Z3226, ,
ICD-O-3
+∞
22.1
20
*
A12AX, ,
ATC
Calcium, combinations with vitamin D and/or other drugs
+∞
22.1
20
*
QBE10, ,
ICD-O-3
+∞
22.1
20
*
B01AB05, ,
ATC
enoxaparin; parenteral
+∞
22.1
20
*
M01AE03, ,
ATC
ketoprofen; systemic, rectal
+∞
20.9
19
*
P01AB01, ,
ATC
metronidazole; oral, rectal
+∞
20.9
19
*
D19, ,
ICD-O-3
+∞
20.9
19
*
SPAT1263, ,
ICD-O-3
+∞
20.9
19
*
Z2221, ,
ICD-O-3
+∞
20.9
19
*
N05CF01, ,
ATC
zopiclone; oral
+∞
19.7
18
*
Q850, ,
ICD-10 Finland
Neurofibromatosis (nonmalignant)
+∞
19.7
18
*
DFF00, ,
ICD-O-3
+∞
19.7
18
*
N06AX11, ,
ATC
mirtazapine; oral
+∞
19.7
18
*
W01, ,
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
+∞
19.7
18
*
TPH04, ,
ICD-O-3
+∞
18.6
17
*
H03AA01, ,
ATC
levothyroxine sodium; systemic
+∞
18.6
17
*
WX700, ,
ICD-O-3
+∞
18.6
17
*
S29, ,
ICD-O-3
+∞
18.6
17
*
C08CA01, ,
ATC
amlodipine; oral
+∞
18.6
17
*
SPAT1325, ,
ICD-O-3
+∞
18.6
17
*
I10, ,
ICD-10 Finland
Essential (primary) hypertension
+∞
18.6
17
*
TQW40, ,
ICD-O-3
+∞
18.6
17
*
Z3229, ,
ICD-O-3
+∞
18.6
17
*
K0364, ,
ICD-O-3
+∞
18.6
17
*
J01MA02, ,
ATC
ciprofloxacin; systemic
+∞
18.6
17
*
WZC30, ,
ICD-O-3
+∞
18.6
17
*
J02AC01, ,
ATC
fluconazole; systemic
+∞
18.6
17
*
R05, ,
ICD-O-3
+∞
18.6
17
*
SDE02, ,
ICD-O-3
+∞
18.6
17
*
SPAT1310, ,
ICD-O-3
+∞
17.4
16
*
UJD10, ,
ICD-O-3
+∞
17.4
16
*
SDA02, ,
ICD-O-3
+∞
17.4
16
*
XCK00, ,
ICD-O-3
+∞
17.4
16
*
Z718, ,
ICD-O-3
+∞
17.4
16
*
R01AD12, ,
ATC
fluticasone furoate; nasal
+∞
17.4
16
*
J01FF01, ,
ATC
clindamycin; systemic
+∞
17.4
16
*
R5110, ,
ICD-O-3
+∞
17.4
16
*
ZXE20, ,
ICD-O-3
+∞
17.4
16
*
ZXD05, ,
ICD-O-3
+∞
17.4
16
*
GD1UA, ,
ICD-O-3
+∞
17.4
16
*
N05BA04, ,
ATC
oxazepam; oral
+∞
17.4
16
*
L28, ,
ICD-O-3
+∞
16.3
15
*
J01EA01, ,
ATC
trimethoprim; systemic
+∞
16.3
15
*
Q850, ,
ICD-O-3
+∞
16.3
15
*
LC2BE, ,
ICD-O-3
+∞
16.3
15
*
N02AA59, ,
ATC
codeine, combinations excl. psycholeptics; systemic
+∞
16.3
15
*
SDE03, ,
ICD-O-3
+∞
16.3
15
*
SPAT1312, ,
ICD-O-3
+∞
16.3
15
*
R5140, ,
ICD-O-3
+∞
16.3
15
*
A02BC05, ,
ATC
esomeprazole; systemic
+∞
16.3
15
*
K045, ,
ICD-O-3
+∞
16.3
15
*
L17, ,
ICD-O-3
+∞
16.3
15
*
OAB43, ,
ICD-O-3
+∞
16.3
15
*
SPAT1253, ,
ICD-O-3
+∞
16.3
15
*
Q8500, ,
ICD-O-3
+∞
16.3
15
*
R05FA02, ,
ATC
opium derivatives and expectorants; systemic
+∞
16.3
15
*
J01EE02, ,
ATC
sulfadiazine and trimethoprim; systemic
+∞
16.3
15
*
XCK10, ,
ICD-O-3
+∞
16.3
15
*
AA1BG, ,
ICD-O-3
+∞
16.3
15
*
SFA40, ,
ICD-O-3
+∞
16.3
15
*
R5180, ,
ICD-10 Finland
Headache
+∞
16.3
15
*
CJE20, ,
ICD-O-3
+∞
15.2
14
*
R53, ,
ICD-O-3
+∞
15.2
14
*
AA1DG, ,
ICD-O-3
+∞
15.2
14
*
H02AB02, ,
ATC
dexamethasone; systemic
+∞
15.2
14
*
H13, ,
ICD-O-3
+∞
15.2
14
*
EBA05, ,
ICD-O-3
+∞
15.2
14
*
SDA04, ,
ICD-O-3
+∞
15.2
14
*
C09CA01, ,
ATC
losartan; oral
+∞
15.2
14
*
2377A, ,
ICD-9 Finland
Neoplasm of uncertain behaviour of endocrine glands and nervous system, Neurofibromatosis
+∞
15.2
14
*
D07AC01, ,
ATC
betamethasone; topical
+∞
15.2
14
*
R01AD08, ,
ATC
fluticasone; nasal
+∞
15.2
14
*
E780, ,
ICD-O-3
+∞
14.0
13
*
N06AB10, ,
ATC
escitalopram; oral
+∞
14.0
13
*
S21, ,
ICD-O-3
+∞
14.0
13
*
FM1EE, ,
ICD-O-3
+∞
14.0
13
*
R05FB02, ,
ATC
cough suppressants and expectorants; systemic
+∞
14.0
13
*
M02AA07, ,
ATC
piroxicam; topical
+∞
14.0
13
*
B02AA02, ,
ATC
tranexamic acid; systemic
+∞
14.0
13
*
Z760, ,
ICD-O-3
+∞
14.0
13
*
N03AX12, ,
ATC
[U] gabapentin; oral
+∞
14.0
13
*
S01CA01, ,
ATC
dexamethasone and antiinfectives; ophthalmic
+∞
14.0
13
*
Q8501, ,
ICD-O-3
+∞
14.0
13
*
74340, ,
ICD-8 Finland
Other congenital anomalies of nervous system, Neurofibromatosis
+∞
14.0
13
*
AAB00, ,
ICD-O-3
+∞
14.0
13
*
J010, ,
ICD-O-3
+∞
12.9
12
*
EBA10, ,
ICD-O-3
+∞
12.9
12
*
SPAT1223, ,
ICD-O-3
+∞
12.9
12
*
Z018, ,
ICD-10 Finland
Other specified special examinations
+∞
12.9
12
*
LCA06, ,
ICD-O-3
+∞
12.9
12
*
J01FA09, ,
ATC
clarithromycin; systemic
+∞
12.9
12
*
M03BC01, ,
ATC
orphenadrine (citrate); systemic
+∞
12.9
12
*
SFC01, ,
ICD-O-3
+∞
12.9
12
*
R074, ,
ICD-10 Finland
Chest pain, unspecified
+∞
12.9
12
*
R03AK07, ,
ATC
formoterol and budesonide; inhalant
+∞
12.9
12
*
QDE10, ,
ICD-O-3
+∞
12.9
12
*
R104, ,
ICD-10 Finland
Other and unspecified abdominal pain
+∞
12.9
12
*
G473, ,
ICD-10 Finland
Sleep apnoea
+∞
12.9
12
*
SPAT1033, ,
ICD-O-3
+∞
12.9
12
*
WZA90, ,
ICD-O-3
+∞
12.9
12
*
R060, ,
ICD-10 Finland
Dyspnoea
+∞
12.9
12
*
SPAT1256, ,
ICD-O-3
+∞
12.9
12
*
J01DA09, ,
ATC
[U] cefadroxil
+∞
12.9
12
*
A03FA01, ,
ATC
metoclopramide; systemic, rectal
+∞
12.9
12
*
D3200, ,
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
+∞
12.9
12
*
S04, ,
ICD-O-3
+∞
11.8
11
*
UJF32, ,
ICD-O-3
+∞
11.8
11
*
Z718, ,
ICD-10 Finland
Other specified counselling
+∞
11.8
11
*
VALMI, ,
ICD-O-3
+∞
11.8
11
*
R238, ,
ICD-O-3
+∞
11.8
11
*
K020, ,
ICD-O-3
+∞
11.8
11
*
TPH07, ,
ICD-O-3
+∞
11.8
11
*
L03, ,
ICD-O-3
+∞
11.8
11
*
NA7CG, ,
ICD-O-3
+∞
11.8
11
*
R74, ,
ICD-O-3
+∞
11.8
11
*
111, ,
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
11.8
11
*
R4120, ,
ICD-O-3
+∞
11.8
11
*
SPAT1149, ,
ICD-O-3
+∞
11.8
11
*
R42, ,
ICD-10 Finland
Dizziness and giddiness
+∞
11.8
11
*
CK2X4, ,
ICD-O-3
+∞
11.8
11
*
R83, ,
ICD-O-3
+∞
11.8
11
*
WW200, ,
ICD-O-3
+∞
11.8
11
*
D01BA02, ,
ATC
terbinafine; oral
+∞
11.8
11
*
M796, ,
ICD-O-3
+∞
11.8
11
*
ZYC01, ,
ICD-O-3
+∞
11.8
11
*
M545, ,
ICD-O-3
+∞
11.8
11
*
OAA65, ,
ICD-O-3
+∞
10.7
10
*
A06AC01, ,
ATC
ispaghula (psylla seeds); oral
+∞
10.7
10
*
D07AC13, ,
ATC
mometasone; topical
+∞
10.7
10
*
SPAT1148, ,
ICD-O-3
+∞
10.7
10
*
H251, ,
ICD-10 Finland
Senile nuclear cataract
+∞
10.7
10
*
C10AA07, ,
ATC
rosuvastatin; oral
+∞
10.7
10
*
JN3AE, ,
ICD-O-3
+∞
10.7
10
*
A97, ,
ICD-O-3
+∞
10.7
10
*
A28, ,
ICD-O-3
+∞
10.7
10
*
SGB10, ,
ICD-O-3
+∞
10.7
10
*
T814, ,
ICD-10 Finland
Infection following a procedure, not elsewhere classified
+∞
10.7
10
*
L08, ,
ICD-O-3
+∞
10.7
10
*
R01BA52, ,
ATC
pseudoephedrine, combinations; oral
+∞
10.7
10
*
L12, ,
ICD-O-3
+∞
10.7
10
*
R05DA20, ,
ATC
opium alkaloids and derivatives - combinations
+∞
10.7
10
*
R03AC03, ,
ATC
terbutaline; inhalant
+∞
10.7
10
*
R06AX27, ,
ATC
desloratadine; oral
+∞
10.7
10
*
J189, ,
ICD-10 Finland
Pneumonia, unspecified
+∞
10.7
10
*
203, ,
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
+∞
10.7
10
*
S060, ,
ICD-10 Finland
Concussion
+∞
10.7
10
*
N05AH04, ,
ATC
quetiapine; oral
+∞
10.7
10
*
ZXC10, ,
ICD-O-3
+∞
10.7
10
*
ACB19, ,
ICD-O-3
+∞
10.7
10
*
NA7DG, ,
ICD-O-3
+∞
10.7
10
*
TQX10, ,
ICD-O-3
+∞
10.7
10
*
Z712, ,
ICD-O-3
+∞
10.7
10
*
N06AB04, ,
ATC
citalopram; systemic
+∞
10.7
10
*
NDR20, ,
ICD-O-3
+∞
9.6
9
*
PH2AE, ,
ICD-O-3
+∞
9.6
9
*
R03BA02, ,
ATC
budesonide; inhalant
+∞
9.6
9
*
M796, ,
ICD-10 Finland
Pain in limb
+∞
9.6
9
*
SPAT1254, ,
ICD-O-3
+∞
9.6
9
*
Z017, ,
ICD-O-3
+∞
9.6
9
*
LX1AE, ,
ICD-O-3
+∞
9.6
9
*
N02CC01, ,
ATC
sumatriptan; nasal, systemic, rectal
+∞
9.6
9
*
R2130, ,
ICD-O-3
+∞
9.6
9
*
FM1AE, ,
ICD-O-3
+∞
9.6
9
*
R01BA51, ,
ATC
phenylpropanolamine, combinations; oral
+∞
9.6
9
*
H81, ,
ICD-O-3
+∞
9.6
9
*
N06AB06, ,
ATC
sertraline; oral
+∞
9.6
9
*
C09CA06, ,
ATC
candesartan; oral
+∞
9.6
9
*
K0382, ,
ICD-O-3
+∞
9.6
9
*
X58, ,
ICD-10 Finland
Exposure to other specified factors
+∞
9.6
9
*
DFF15, ,
ICD-O-3
+∞
9.6
9
*
K021, ,
ICD-10 Finland
Caries of dentine
+∞
9.6
9
*
E7801, ,
ICD-10 Finland
Pure hypercholesterolaemia
+∞
9.6
9
*
UKC02, ,
ICD-O-3
+∞
9.6
9
*
D3330, ,
ICD-O-3
+∞
9.6
9
*
SPAT1250, ,
ICD-O-3
+∞
9.6
9
*
R104, ,
ICD-O-3
+∞
9.6
9
*
NA1BG, ,
ICD-O-3
+∞
9.6
9
*
OAB42, ,
ICD-O-3
+∞
9.6
9
*
Q859, ,
ICD-10 Finland
Phakomatosis, unspecified
+∞
9.6
9
*
N07CA01, ,
ATC
betahistine; oral
+∞
9.6
9
*
G04CA02, ,
ATC
tamsulosin; oral
+∞
9.6
9
*
SDA01, ,
ICD-O-3
+∞
9.6
9
*
Z004, ,
ICD-10 Finland
General psychiatric examination, not elsewhere classified
+∞
9.6
9
*
SPAT1260, ,
ICD-O-3
+∞
8.5
8
*
6500B, ,
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
+∞
8.5
8
*
M751, ,
ICD-O-3
+∞
8.5
8
*
JN1AE, ,
ICD-O-3
+∞
8.5
8
*
O800, ,
ICD-10 Finland
Spontaneous vertex delivery
+∞
8.5
8
*
R103, ,
ICD-10 Finland
Pain localized to other parts of lower abdomen
+∞
8.5
8
*
G473, ,
ICD-O-3
+∞
8.5
8
*
R01AD58, ,
ATC
fluticasone, combinations; nasal
+∞
8.5
8
*
R42, ,
ICD-O-3
+∞
8.5
8
*
G03AC03, ,
ATC
levonorgestrel; oral, implant
+∞
8.5
8
*
N03AF01, ,
ATC
carbamazepine; oral, rectal
+∞
8.5
8
*
N920, ,
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
+∞
8.5
8
*
TQW99, ,
ICD-O-3
+∞
8.5
8
*
EP1AE, ,
ICD-O-3
+∞
8.5
8
*
R103, ,
ICD-O-3
+∞
8.5
8
*
A02BA02, ,
ATC
ranitidine; systemic
+∞
8.5
8
*
WYA30, ,
ICD-O-3
+∞
8.5
8
*
F329, ,
ICD-10 Finland
Depressive episode, unspecified
+∞
8.5
8
*
J05AB01, ,
ATC
aciclovir; systemic
+∞
8.5
8
*
M01AX17, ,
ATC
nimesulide; oral
+∞
8.5
8
*
ZXD20, ,
ICD-O-3
+∞
8.5
8
*
C07AA05, ,
ATC
propranolol; systemic
+∞
8.5
8
*
G409, ,
ICD-10 Finland
Epilepsy, unspecified
+∞
8.5
8
*
R568, ,
ICD-10 Finland
Other and unspecified convulsions
+∞
8.5
8
*
K85, ,
ICD-O-3
+∞
8.5
8
*
R298, ,
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
+∞
8.5
8
*
Z000, ,
ICD-10 Finland
General medical examination
+∞
8.5
8
*
U02, ,
ICD-O-3
+∞
8.5
8
*
E000001, ,
ATC
+∞
8.5
8
*
LC2AE, ,
ICD-O-3
+∞
8.5
8
*
K0510, ,
ICD-O-3
+∞
8.5
8
*
M01AC06, ,
ATC
meloxicam; systemic, rectal
+∞
8.5
8
*
182, ,
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
+∞
8.5
8
*
XLD00, ,
ICD-O-3
+∞
8.5
8
*
ND2AA, ,
ICD-O-3
+∞
8.5
8
*
A02BC03, ,
ATC
lansoprazole; oral
+∞
8.5
8
*
OAA67, ,
ICD-O-3
+∞
8.5
8
*
E7801, ,
ICD-O-3
+∞
8.5
8
*
R21, ,
ICD-O-3
+∞
8.5
8
*
C09AA05, ,
ATC
ramipril; oral
+∞
8.5
8
*
SPAT1308, ,
ICD-O-3
+∞
8.5
8
*
J069, ,
ICD-10 Finland
Acute upper respiratory infection, unspecified
+∞
8.5
8
*
A02BC01, ,
ATC
omeprazole; systemic
+∞
8.5
8
*
A06AD11, ,
ATC
lactulose; oral
+∞
8.5
8
*
ZXM10, ,
ICD-O-3
+∞
8.5
8
*
N300, ,
ICD-O-3
+∞
8.5
8
*
QDB10, ,
ICD-O-3
+∞
8.5
8
*
Z508, ,
ICD-10 Finland
Care involving use of other rehabilitation procedures
+∞
8.5
8
*
UDC00, ,
ICD-O-3
+∞
8.5
8
*
SPAT1230, ,
ICD-O-3
+∞
8.5
8
*
C724, 9560, 0
O3
89.4
7.6
8
*
SCA02, ,
ICD-O-3
+∞
7.4
7
*
K0365, ,
ICD-O-3
+∞
7.4
7
*
QBA25, ,
ICD-O-3
+∞
7.4
7
*
SPAT1156, ,
ICD-O-3
+∞
7.4
7
*
Z039, ,
ICD-10 Finland
Observation for suspected disease or condition, unspecified
+∞
7.4
7
*
C03EA01, ,
ATC
hydrochlorothiazide and potassium-sparing agents; oral
+∞
7.4
7
*
NH1AA, ,
ICD-O-3
+∞
7.4
7
*
ZY020, ,
ICD-O-3
+∞
7.4
7
*
N06AX16, ,
ATC
venlafaxine; oral
+∞
7.4
7
*
A23, ,
ICD-O-3
+∞
7.4
7
*
R03DC03, ,
ATC
montelukast; oral
+∞
7.4
7
*
N02BF01, ,
ATC
gabapentin; oral
+∞
7.4
7
*
N05CF02, ,
ATC
zolpidem; oral
+∞
7.4
7
*
Z0389, ,
ICD-10 Finland
Observation for other suspected diseases and conditions
+∞
7.4
7
*
J01MA06, ,
ATC
norfloxacin; oral
+∞
7.4
7
*
DE2CG, ,
ICD-O-3
+∞
7.4
7
*
L309, ,
ICD-O-3
+∞
7.4
7
*
K044, ,
ICD-O-3
+∞
7.4
7
*
ZY010, ,
ICD-O-3
+∞
7.4
7
*
SGA02, ,
ICD-O-3
+∞
7.4
7
*
DAX00, ,
ICD-O-3
+∞
7.4
7
*
D11, ,
ICD-O-3
+∞
7.4
7
*
Z2446, ,
ICD-O-3
+∞
7.4
7
*
TNX32, ,
ICD-O-3
+∞
7.4
7
*
N03AF02, ,
ATC
oxcarbazepine; oral
+∞
7.4
7
*
R03BA01, ,
ATC
beclometasone; inhalant
+∞
7.4
7
*
N03AG01, ,
ATC
valproic acid; systemic, rectal
+∞
7.4
7
*
ZXE11, ,
ICD-O-3
+∞
7.4
7
*
X59, ,
ICD-10 Finland
Exposure to unspecified factor
+∞
7.4
7
*
GD1QA, ,
ICD-O-3
+∞
7.4
7
*
H01, ,
ICD-O-3
+∞
7.4
7
*
NA3BG, ,
ICD-O-3
+∞
7.4
7
*
H0410, ,
ICD-O-3
+∞
7.4
7
*
H02, ,
ICD-O-3
+∞
7.4
7
*
N30, ,
ICD-O-3
+∞
7.4
7
*
S01GX01, ,
ATC
cromoglicic acid; ophthalmic
+∞
7.4
7
*
F510, ,
ICD-O-3
+∞
7.4
7
*
M255, ,
ICD-O-3
+∞
7.4
7
*
NA1CG, ,
ICD-O-3
+∞
7.4
7
*
D321, ,
ICD-10 Finland
Benign neoplasm: Spinal meninges
+∞
7.4
7
*
M05BA04, ,
ATC
alendronic acid; oral
+∞
7.4
7
*
G01AA10, ,
ATC
clindamycin; vaginal
+∞
7.4
7
*
Z974, ,
ICD-10 Finland
Presence of external hearing-aid
+∞
7.4
7
*
ZXE30, ,
ICD-O-3
+∞
7.4
7
*
ND1AA, ,
ICD-O-3
+∞
7.4
7
*
N05BA01, ,
ATC
diazepam; systemic, rectal
+∞
7.4
7
*
Z048, ,
ICD-10 Finland
Examination and observation for other specified reasons
+∞
7.4
7
*
J01MA12, ,
ATC
levofloxacin; systemic
+∞
7.4
7
*
N06CA01, ,
ATC
amitriptyline and psycholeptics; systemic
+∞
7.4
7
*
QCE10, ,
ICD-O-3
+∞
7.4
7
*
D361, ,
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
+∞
7.4
7
*
TLC00, ,
ICD-O-3
+∞
7.4
7
*
R060, ,
ICD-O-3
+∞
7.4
7
*
205, ,
Kela drug reimbursment
Chronic hypertension
+∞
7.4
7
*
SGC10, ,
ICD-O-3
+∞
7.4
7
*
D259, ,
ICD-10 Finland
Leiomyoma of uterus, unspecified
+∞
7.4
7
*
W00, ,
ICD-10 Finland
Fall on same level involving ice and snow
+∞
7.4
7
*
SPAT1315, ,
ICD-O-3
+∞
7.4
7
*
D3345, ,
ICD-10 Finland
Benign Schwannom in the nerve root of the spinal cord
+∞
7.4
7
*
K86, ,
ICD-O-3
+∞
7.4
7
*
R01AD01, ,
ATC
beclometasone; nasal
+∞
7.4
7
*
K0530, ,
ICD-O-3
+∞
7.4
7
*
SAD01, ,
ICD-O-3
+∞
7.4
7
*
SPAT1283, ,
ICD-O-3
+∞
7.4
7
*
J01FA01, ,
ATC
erythromycin; systemic
+∞
7.4
7
*
GD1PA, ,
ICD-O-3
+∞
7.4
7
*
L11, ,
ICD-O-3
+∞
7.4
7
*
SPAT1240, ,
ICD-O-3
+∞
7.4
7
*
C09AA02, ,
ATC
enalapril; systemic
+∞
7.4
7
*
F3310, ,
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
+∞
7.4
7
*
R02, ,
ICD-O-3
+∞
7.4
7
*
NA3CG, ,
ICD-O-3
+∞
7.4
7
*
XA800, ,
ICD-O-3
+∞
7.4
7
*
J010, ,
ICD-10 Finland
Acute maxillary sinusitis
+∞
6.3
6
*
CS424, ,
ICD-O-3
+∞
6.3
6
*
J02AC02, ,
ATC
itraconazole; systemic
+∞
6.3
6
*
EB1CA, ,
ICD-O-3
+∞
6.3
6
*
CK2S4, ,
ICD-O-3
+∞
6.3
6
*
E785, ,
ICD-10 Finland
Hyperlipidaemia, unspecified
+∞
6.3
6
*
SGA01, ,
ICD-O-3
+∞
6.3
6
*
R5130, ,
ICD-O-3
+∞
6.3
6
*
AAB10, ,
ICD-O-3
+∞
6.3
6
*
R5120, ,
ICD-O-3
+∞
6.3
6
*
P20, ,
ICD-O-3
+∞
6.3
6
*
Z014, ,
ICD-O-3
+∞
6.3
6
*
G4022, ,
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
6.3
6
*
WF002, ,
ICD-O-3
+∞
6.3
6
*
H02AB07, ,
ATC
prednisone; oral
+∞
6.3
6
*
WX320, ,
ICD-O-3
+∞
6.3
6
*
M480, ,
ICD-10 Finland
Spinal stenosis
+∞
6.3
6
*
K040, ,
ICD-O-3
+∞
6.3
6
*
SPAT1229, ,
ICD-O-3
+∞
6.3
6
*
Z024, ,
ICD-O-3
+∞
6.3
6
*
N03AX14, ,
ATC
levetiracetam; systemic
+∞
6.3
6
*
ZXE05, ,
ICD-O-3
+∞
6.3
6
*
H904, ,
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
+∞
6.3
6
*
M03BC51, ,
ATC
orphenadrine, combinations; systemic
+∞
6.3
6
*
SGA03, ,
ICD-O-3
+∞
6.3
6
*
SPAT1324, ,
ICD-O-3
+∞
6.3
6
*
L29, ,
ICD-O-3
+∞
6.3
6
*
U072, ,
ICD-O-3
+∞
6.3
6
*
HA1AA, ,
ICD-O-3
+∞
6.3
6
*
K409, ,
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
+∞
6.3
6
*
Z011, ,
ICD-O-3
+∞
6.3
6
*
N832, ,
ICD-10 Finland
Other and unspecified ovarian cysts
+∞
6.3
6
*
D07AB02, ,
ATC
hydrocortisone butyrate; topical
+∞
6.3
6
*
D377, ,
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
+∞
6.3
6
*
Z014, ,
ICD-10 Finland
Gynaecological examination (general)(routine)
+∞
6.3
6
*
Z027, ,
ICD-O-3
+∞
6.3
6
*
J459, ,
ICD-O-3
+∞
6.3
6
*
I499, ,
ICD-O-3
+∞
6.3
6
*
WX105, ,
ICD-O-3
+∞
6.3
6
*
R509, ,
ICD-10 Finland
Fever, unspecified
+∞
6.3
6
*
WX602, ,
ICD-O-3
+∞
6.3
6
*
KH1AE, ,
ICD-O-3
+∞
6.3
6
*
B01AB10, ,
ATC
tinzaparin; parenteral
+∞
6.3
6
*
S15, ,
ICD-O-3
+∞
6.3
6
*
R13, ,
ICD-10 Finland
Dysphagia
+∞
6.3
6
*
A499, ,
ICD-10 Finland
Bacterial infection, unspecified
+∞
6.3
6
*
SPAT1043, ,
ICD-O-3
+∞
6.3
6
*
65000, ,
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
+∞
6.3
6
*
R074, ,
ICD-O-3
+∞
6.3
6
*
Z2445, ,
ICD-O-3
+∞
6.3
6
*
M54, ,
ICD-O-3
+∞
6.3
6
*
C01DA08, ,
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
+∞
6.3
6
*
J01MA14, ,
ATC
moxifloxacin; systemic
+∞
6.3
6
*
UDQ12, ,
ICD-O-3
+∞
6.3
6
*
CS444, ,
ICD-O-3
+∞
6.3
6
*
A10BA02, ,
ATC
metformin; oral
+∞
6.3
6
*
UJF30, ,
ICD-O-3
+∞
6.3
6
*
L82, ,
ICD-O-3
+∞
6.3
6
*
D07CA01, ,
ATC
hydrocortisone and antibiotics; topical
+∞
6.3
6
*
Z461, ,
ICD-10 Finland
Fitting and adjustment of hearing aid
+∞
6.3
6
*
SAB01, ,
ICD-O-3
+∞
6.3
6
*
M01AG02, ,
ATC
tolfenamic acid; oral, rectal
+∞
6.3
6
*
M190, ,
ICD-10 Finland
Primary arthrosis of other joints
+∞
6.3
6
*
Z363, ,
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
+∞
6.3
6
*
A03, ,
ICD-O-3
+∞
6.3
6
*
C05AA08, ,
ATC
fluocortolone; rectal, topical
+∞
6.3
6
*
EP1CG, ,
ICD-O-3
+∞
6.3
6
*
R05, ,
ICD-10 Finland
Cough
+∞
6.3
6
*
NA1AD, ,
ICD-O-3
+∞
6.3
6
*
P01, ,
ICD-O-3
+∞
6.3
6
*
L15, ,
ICD-O-3
+∞
6.3
6
*
D01AC20, ,
ATC
imidazoles/triazoles in combination with corticosteroids; topical
+∞
6.3
6
*
N40, ,
ICD-10 Finland
Hyperplasia of prostate
+∞
6.3
6
*
N03AE01, ,
ATC
clonazepam; systemic
+∞
6.3
6
*
OAB48, ,
ICD-O-3
+∞
6.3
6
*
H400, ,
ICD-10 Finland
Glaucoma suspect
+∞
6.3
6
*
HA1AE, ,
ICD-O-3
+∞
6.3
6
*
XF600, ,
ICD-O-3
+∞
6.3
6
*
104, ,
Kela drug reimbursment
Thyroid insufficiency
+∞
6.3
6
*
Z015, ,
ICD-10 Finland
Diagnostic skin and sensitization tests
+∞
6.3
6
*
R1250, ,
ICD-O-3
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
20
45
5.88
9.07
8.4
5.8
0.19
2.12
mmol/l
1.00
15
39
36
166
3.48
6.04
2.4
2.3
—
—
—
0
0
20
62
4.15
6.03
1.4
1.2
—
—
—
0
0
16
33
6.01
5.91
7.6
10.2
24.45
24.25
mmol/l
0.07
16
33
16
38
5.18
5.26
1.3
1.4
—
—
—
0
0
15
41
4.41
5.26
10.8
9.7
—
—
—
0
0
10
14
8.16
4.85
12.8
5.5
24.40
25.43
mmol/l
—
10
14
15
44
4.09
4.79
11.9
5.9
108.20
104.30
mmol/l
1.52
15
44
7
6
12.79
4.38
3.1
6.0
2.43
0.98
nmol/l
—
7
6
13
32
4.77
4.18
9.9
7.0
1.15
1.17
mmol/l
0.04
13
32
11
24
5.25
3.95
12.8
5.3
96.63
94.81
%
1.94
11
24
11
25
5.04
3.82
12.8
5.0
0.62
0.75
%
0.45
11
25
11
25
5.04
3.82
12.4
5.0
1.06
1.28
%
0.51
11
25
6
6
10.80
3.57
3.0
3.3
382.50
317.67
umol/l
—
6
6
6
6
10.80
3.57
2.5
1.2
—
—
—
0
0
6
6
10.80
3.57
2.5
1.2
0.58
0.42
nmol/l
—
6
6
37
217
2.55
3.50
3.0
1.7
—
—
—
0
0
9
20
5.01
3.24
10.1
7.0
—
—
—
0
0
9
22
4.55
3.00
1.2
2.3
0.67
0.03
e6/l
—
9
22
16
68
2.77
2.81
1.3
1.6
—
—
—
0
0
33
200
2.26
2.73
9.8
8.9
1.16
1.15
inr
—
8
52
32
193
2.24
2.66
7.8
6.3
36.81
35.96
g/l
0.39
27
186
7
17
4.46
2.43
4.0
2.3
—
—
—
0
0
6
153
0.33
2.12
5.2
2.0
—
—
—
0
0
8
27
3.22
2.01
4.4
5.6
—
—
—
0
0
5
11
4.81
1.97
1.6
1.3
—
—
—
0
0
7
22
3.42
1.94
2.6
6.9
142.57
130.27
g/l
—
7
22
14
68
2.33
1.86
2.4
1.4
—
—
—
0
0
27
171
1.96
1.85
2.1
1.9
103.72
94.87
pmol/l
0.39
16
85
47
368
1.90
1.61
3.4
3.2
—
—
—
0
0
5
122
0.36
1.57
4.6
1.8
—
—
—
0
0
6
25
2.53
1.27
2.3
6.9
—
—
—
0
0
41
326
1.65
1.16
7.3
12.0
4.49
3.95
e9/l
0.72
36
289
12
67
1.96
1.13
4.1
2.7
—
—
—
0
0
49
410
1.70
1.11
7.8
7.6
71.31
77.43
u/l
0.71
49
379
5
21
2.49
1.11
3.2
4.4
27.04
23.90
mmol/l
—
5
21
5
22
2.37
1.05
4.8
4.1
—
—
—
0
0
56
497
1.72
0.89
18.0
15.8
14.21
14.43
%
0.12
56
491
11
65
1.83
0.88
2.5
1.9
344.73
386.03
nmol/l
0.40
11
58
35
281
1.51
0.86
5.8
8.9
0.27
0.18
e9/l
0.96
28
253
20
145
1.54
0.78
5.6
9.9
—
—
—
0
0
61
561
1.85
0.76
19.1
12.4
21.73
20.27
mg/l
0.13
48
416
5
94
0.50
0.73
1.4
1.6
—
—
—
0
0
5
26
1.99
0.72
2.0
2.2
—
—
—
0
0
34
279
1.44
0.71
5.4
8.2
2.12
1.89
e9/l
0.26
27
254
33
271
1.42
0.68
5.5
8.3
0.05
0.04
e9/l
0.81
25
242
18
131
1.51
0.68
4.3
3.7
—
—
—
0
0
0
20
0.00
0.61
0.0
1.3
—
—
—
0
0
63
594
1.82
0.61
17.7
11.0
—
—
—
0
0
31
258
1.37
0.57
7.7
9.8
0.00
0.00
e9/l
-0.00
21
212
15
110
1.47
0.55
4.8
4.3
—
—
—
0
0
32
272
1.33
0.50
5.7
8.2
0.67
0.57
e9/l
1.25
25
242
7
47
1.54
0.49
2.1
1.5
—
—
—
0
0
6
93
0.61
0.46
4.8
1.7
—
—
—
0
0
19
152
1.35
0.43
1.7
1.8
1.34
1.39
mmol/l
0.12
19
133
21
171
1.33
0.43
3.6
3.1
19.83
19.82
ng/l
0.00
11
101
0
16
0.00
0.41
0.0
2.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
42
381
1.27
0.36
4.1
4.1
—
—
—
0
0
6
43
1.43
0.36
3.2
5.1
62.50
71.38
e9/l
—
6
33
17
141
1.27
0.30
3.8
2.7
—
—
—
0
0
8
65
1.26
0.28
1.3
1.1
—
—
—
0
0
5
39
1.30
0.23
1.0
1.3
—
—
—
0
0
29
262
1.19
0.23
6.5
8.5
—
—
—
0
0
0
12
0.00
0.21
0.0
2.8
—
23.20
—
0
7
0
13
0.00
0.21
0.0
1.9
—
9.23
—
0
13
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
18
203
0.85
0.18
3.2
2.4
—
—
—
0
0
17
153
1.15
0.12
3.1
3.0
—
—
—
0
0
5
44
1.15
0.10
17.4
4.0
—
—
—
0
0
6
72
0.82
0.08
1.3
1.3
—
—
—
0
0
9
102
0.86
0.07
1.8
1.5
21.07
21.64
nmol/l
—
9
90
15
161
0.91
0.06
2.5
2.7
—
—
—
0
0
35
340
1.06
0.04
4.2
4.1
—
39.80
—
0
5
17
171
0.99
0.00
1.4
1.5
—
—
—
0
0
14
137
1.03
0.00
3.7
2.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.9
—
—
—
0
0
5
50
1.00
-0.00
2.2
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
6.03
—
0
6
5
56
0.88
-0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
25.67
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
280.17
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
222.43
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1597.40
—
0
5
0
5
0.00
-0.00
0.0
38.0
—
154.00
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
0.64
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
37.74
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
41.42
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: Q17_NEUROFIBROMATOSIS_2 – Neurofibromatosis, type 2

GWS hits: 3

This endpoint is excluded (different definition than used in FinnGen).