Dacryoadenitis

H7_DACRYOADENITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H04.0
  • Hospital discharge: ICD-9 3750
  • Hospital discharge: ICD-8 3680[0-1]
  • Cause of death: ICD-10 H04.0
  • Cause of death: ICD-9 3750
  • Cause of death: ICD-8 3680[0-1]

2 out of 7 registries used, show all original rules.

324

4. Check minimum number of events

None

324

5. Include endpoints

None

324

6. Filter based on genotype QC (FinnGen only)

288

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H04
Name in latin
Dacryoadenitis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2212 1511 693
Only index persons 1950 1344 606
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.02
Only index persons 0.04 0.05 0.02
Median age at first event (years)
Whole population 53.96 56.86 47.52
Only index persons 51.95 55.26 44.61

-FinnGen-

Key figures

All Female Male
Number of individuals 288 203 85
Unadjusted period prevalence (%) 0.06 0.07 0.04
Median age at first event (years) 54.59 54.03 55.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
297
Matched controls
2970
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H04.0
ICD-10 Finland
Dacryoadenitis
+∞
307.7
270
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
401.3
90.0
86
*
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
+∞
60.5
56
*
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
+∞
58.3
54
*
H04.10
ICD-10 Finland
Dry eye syndrome
9.8
55.8
74
97
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
122.6
48.5
51
5
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
+∞
47.2
44
*
CCD50
NOMESCO Finland
Dacryocystorhinostomy with insertion of tube
+∞
26.4
25
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.3
22.8
152
717
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.2
21.4
176
927
H01.0
ICD-10 Finland
Blepharitis
6.0
19.1
36
67
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
5.0
19.0
45
103
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
190.9
17.7
18
*
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
190.9
17.7
18
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.2
17.6
88
341
UDH02
NOMESCO Finland
Rhinopharyngoscopy
4.7
16.4
41
98
S01GX01
ATC
cromoglicic acid; ophthalmic
3.1
16.3
86
343
H02AB06
ATC
prednisolone; systemic
2.7
15.8
175
1025
36800
ICD-8 Finland
Inflammation of lachrymal glands and ducts, Dacryadenitis acuta. Abscessus glandulae lacrimalis
+∞
15.8
15
*
H02.4
ICD-10 Finland
Ptosis of eyelid
56.1
13.9
16
*
H57.1
ICD-10 Finland
Ocular pain
6.3
13.8
24
41
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
6.0
13.1
24
43
H02AB04
ATC
methylprednisolone; systemic
3.1
12.9
64
243
H02.3
ICD-10 Finland
Blepharochalasis
21.0
11.3
16
8
J01DB01
ATC
cefalexin; oral
3.2
10.8
261
2051
F29
ICPC
Eye symptom/complaint other
3.2
10.7
48
171
F03
ICPC
Eye discharge
3.7
10.4
34
99
L04AA06
ATC
mycophenolic acid; systemic
17.5
10.0
15
9
H16.0
ICD-10 Finland
Corneal ulcer
4.4
9.9
26
64
L04AX03
ATC
methotrexate; systemic
3.2
9.5
41
143
S01AD03
ATC
aciclovir; ophthalmic
5.0
9.2
20
42
L04AX01
ATC
azathioprine; systemic
5.1
9.0
19
39
ZXE00
NOMESCO Finland
One hour or less
2.1
8.9
130
799
R01AD08
ATC
fluticasone; nasal
2.2
8.9
97
532
ZXA00
NOMESCO Finland
Right side
2.2
8.9
93
502
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
8.5
37
129
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.0
8.5
41
152
J01FF01
ATC
clindamycin; systemic
2.2
8.4
92
503
36802
ICD-8 Finland
Inflammation of lachrymal glands and ducts, Obstructio, stenosis viarum lacrimalium
+∞
8.4
8
*
36801
ICD-8 Finland
Inflammation of lachrymal glands and ducts, Dacryadenitis chronica
+∞
8.4
8
*
R06AE07
ATC
cetirizine; oral
2.0
8.1
140
908
A03CA02
ATC
clidinium and psycholeptics; oral
3.4
7.7
28
87
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
3.3
7.6
30
99
A05AA02
ATC
ursodeoxycholic acid; oral
8.7
7.4
15
18
CCA30
NOMESCO Finland
Incision of lacrimal sac
+∞
7.3
7
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.8
7.2
39
154
D07AC01
ATC
betamethasone; topical
2.0
7.0
114
716
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.7
7.0
41
169
UDM02
NOMESCO Finland
Sinoscopy
7.0
6.9
16
24
J01FA10
ATC
azithromycin; systemic
1.9
6.9
175
1271
H04.2
ICD-10 Finland
Epiphora
41.0
6.8
8
*
F73
ICPC
Eye infection/inflammation other
6.7
6.7
16
25
UJF32
NOMESCO Finland
Coloscopy
2.0
6.7
86
495
L04AD01
ATC
ciclosporin; systemic
12.6
6.6
11
9
XCK00
NOMESCO Finland
Perimetry
3.2
6.6
27
91
H16.8
ICD-10 Finland
Other keratitis
71.3
6.4
7
*
S01XA18
ATC
ciclosporin; ophthalmic
71.3
6.4
7
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
6.4
117
758
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
6.4
147
1026
R06AE09
ATC
levocetirizine; oral
2.4
6.3
48
223
A02BA04
ATC
nizatidine; systemic
2.9
6.3
30
110
R01AD09
ATC
mometasone; nasal
1.9
6.3
137
938
H05.0
ICD-10 Finland
Acute inflammation of orbit
+∞
6.3
6
*
H02.2
ICD-10 Finland
Lagophthalmos
+∞
6.3
6
*
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
6.3
6
*
CCD40
NOMESCO Finland
Percutaneous dacryocystorhinostomy
+∞
6.3
6
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
27.3
6.3
8
*
H00.03
ICD-10 Finland
Preseptal cellulite in the eyelid
27.3
6.3
8
*
H26.4
ICD-10 Finland
After-cataract
2.5
6.1
40
174

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
82
359
2.77
12.78
1.6
1.4
386.67
494.51
titre
0.35
21
91
85
454
2.22
8.23
1.4
1.3
2.70
9.73
u/ml
2.11
35
188
17
21
8.51
8.20
1.9
1.1
—
—
—
0
0
89
501
2.11
7.46
1.4
1.3
19.14
33.23
iu/ml
1.27
24
158
167
1175
1.96
7.43
6.3
4.5
35.54
35.56
g/l
0.02
157
1112
28
92
3.26
7.10
1.8
1.3
—
—
—
0
0
190
1429
1.91
6.59
5.4
4.0
0.00
0.01
estimate
0.50
38
286
187
1412
1.88
6.26
5.3
3.9
0.00
0.00
estimate
-0.00
41
310
16
39
4.28
6.17
4.4
3.5
4.03
4.30
e9/l
0.18
16
39
123
819
1.86
6.14
12.3
5.1
—
—
—
0
0
187
1418
1.86
6.11
5.4
3.9
0.00
5.98
estimate
0.50
42
314
123
830
1.82
5.80
4.5
3.6
7.40
7.40
ph
0.18
93
593
58
306
2.11
5.63
2.4
1.7
—
—
—
0
0
153
1110
1.78
5.60
4.5
3.5
6.28
6.25
ph
0.14
81
631
237
1970
2.01
5.50
11.3
7.6
78.35
79.27
u/l
0.11
228
1862
60
330
2.03
5.20
3.5
2.2
145.22
117.92
ug/g
0.29
50
256
216
1766
1.82
4.97
4.6
4.1
—
16836.17
—
0
6
17
54
3.28
4.56
4.8
3.3
53.82
61.58
%
1.91
17
54
27
113
2.53
4.46
2.4
1.6
20.36
8.00
iu/ml
—
7
27
234
1991
1.83
4.34
5.5
4.5
14.82
14.92
pmol/l
0.29
219
1812
168
1322
1.62
4.04
7.2
7.2
1.22
1.21
mmol/l
0.08
148
1146
166
1304
1.62
4.01
11.5
5.3
0.04
0.04
e9/l
0.56
149
1120
165
1300
1.61
3.90
11.6
5.3
0.58
0.56
e9/l
0.41
148
1115
85
571
1.68
3.80
2.0
1.4
2.74
2.41
g/l
0.87
53
333
277
2527
2.43
3.78
25.6
18.8
3.98
3.96
mmol/l
0.74
272
2467
160
1260
1.58
3.72
4.2
3.1
111.58
111.05
ug/l
0.01
153
1163
59
360
1.80
3.69
2.5
2.1
—
—
—
0
0
101
716
1.62
3.64
2.5
2.2
2.88
3.05
mg/l
0.37
93
612
152
1188
1.57
3.62
3.1
2.6
81.06
77.85
nmol/l
0.76
144
1070
92
638
1.64
3.62
1.5
1.3
2.07
1.63
u/ml
0.13
27
161
10
21
4.89
3.58
1.0
1.2
—
—
—
0
0
167
1338
1.57
3.54
11.6
5.4
1.79
1.96
e9/l
0.94
154
1183
168
1348
1.57
3.53
12.1
5.6
0.19
0.18
e9/l
0.26
154
1175
111
813
1.58
3.47
3.8
3.2
69.63
49.95
mg/l
0.27
72
528
260
2334
1.91
3.44
6.8
5.5
1.74
1.90
mu/l
1.75
246
2142
15
53
2.93
3.41
3.1
3.2
1.27
2.93
mmol/l
—
9
32
7
10
7.14
3.38
1.0
1.0
1636.14
1464.10
miu/ml
—
7
10
116
865
1.56
3.32
3.7
3.1
7.89
7.37
mmol/l
0.49
101
741
49
294
1.80
3.23
1.5
1.4
—
—
—
0
0
151
1201
1.52
3.19
6.9
6.1
1.22
1.22
mmol/l
0.16
145
1115
150
1193
1.52
3.16
17.2
10.7
0.00
0.00
e9/l
0.56
127
975
138
1080
1.52
3.12
5.4
3.9
0.09
0.01
estimate
0.43
35
256
11
30
3.77
3.12
2.1
1.4
—
—
—
0
0
11
30
3.77
3.12
2.1
1.4
—
—
—
0
0
11
30
3.77
3.12
2.1
1.4
—
—
—
0
0
11
30
3.77
3.12
2.1
1.4
—
—
—
0
0
132
1027
1.51
3.05
5.7
3.9
126.35
81.32
e6/l
0.30
95
726
271
2487
2.02
3.04
22.9
15.8
19.06
24.15
mg/l
2.18
240
2041
281
2614
2.39
3.04
16.8
11.3
24.12
24.42
u/l
0.13
274
2541
33
180
1.94
2.92
1.8
2.4
—
—
—
0
0
177
1473
1.50
2.90
12.8
9.0
3.85
4.12
e9/l
1.09
158
1274
281
2621
2.34
2.90
28.6
20.5
76.84
75.41
umol/l
0.43
281
2587
265
2422
1.87
2.89
5.3
4.9
4.64
4.63
mmol/l
0.06
249
2240
49
304
1.73
2.89
1.6
1.6
—
—
—
0
0
268
2461
1.91
2.84
6.2
5.6
2.71
2.68
mmol/l
0.21
253
2272
77
540
1.57
2.82
3.8
2.9
529.03
513.54
mosm/kgh2o
0.31
69
478
110
836
1.50
2.79
4.7
3.9
12.71
8.31
mg/mmol
0.34
69
529
169
1400
1.48
2.79
7.8
6.2
10.61
11.05
umol/l
0.30
160
1340
16
66
2.51
2.76
2.1
3.8
0.30
1.10
index
—
10
40
18
79
2.36
2.73
1.4
1.8
4.13
3.01
iu/l
—
6
22
118
914
1.48
2.71
3.7
3.1
—
—
—
0
0
105
796
1.49
2.68
4.2
3.0
0.28
0.42
e6/l
0.55
81
582
83
599
1.54
2.67
2.5
1.7
0.91
1.32
mg/l
1.11
64
484
148
1204
1.46
2.62
12.8
5.6
9.28
8.56
%
2.00
142
1139
86
628
1.52
2.61
3.6
2.6
5.85
6.17
e6/l
0.08
77
579
34
196
1.83
2.56
1.4
1.5
—
—
—
0
0
147
1200
1.45
2.53
12.8
5.5
0.73
0.68
%
0.69
139
1130
254
2316
1.67
2.50
7.1
6.2
39.76
39.26
mmol/mol
0.37
239
2169
106
815
1.47
2.49
6.2
4.0
0.00
0.00
estimate
-0.00
37
295
147
1203
1.44
2.48
12.6
5.4
2.87
2.76
%
0.28
141
1136
103
788
1.47
2.48
3.2
3.4
1122.39
1561.33
ng/l
0.80
91
671
26
139
1.95
2.45
1.5
1.2
—
—
—
0
0
260
2388
1.71
2.45
5.6
5.0
5.83
5.93
mmol/l
0.71
239
2184
101
773
1.46
2.42
7.9
6.1
—
—
—
0
0
6
12
5.08
2.41
1.3
3.5
329.00
1039.58
u/ml
—
6
12
149
1228
1.43
2.39
12.6
5.5
28.80
27.57
%
0.79
143
1174
13
52
2.57
2.39
1.6
5.5
—
—
—
0
0
41
256
1.70
2.37
6.8
3.0
1.34
2.10
mmol/l
0.98
36
221
117
924
1.44
2.37
4.4
3.2
26.19
49.38
e6/l
1.01
93
705
11
40
2.82
2.30
1.9
1.3
—
—
—
0
0
11
40
2.82
2.30
1.9
1.5
—
—
—
0
0
94
718
1.45
2.25
4.6
4.2
—
—
—
0
0
230
2067
1.50
2.23
28.8
20.3
331.36
331.35
g/l
0.00
230
2060
273
2555
1.85
2.22
19.1
14.4
—
—
—
0
0
106
830
1.43
2.22
4.1
2.5
58.06
60.54
u/l
0.15
96
772
54
371
1.56
2.14
5.3
6.3
104.15
104.18
mmol/l
0.02
54
371
147
1226
1.39
2.12
21.6
14.0
1.29
1.25
inr
0.33
126
1019
5
10
5.06
2.08
1.2
1.2
—
—
—
0
0
260
2411
1.63
2.07
5.2
4.8
1.47
1.50
mmol/l
0.37
243
2225
118
955
1.39
2.01
3.0
3.3
2.37
2.35
mmol/l
0.45
110
869
55
386
1.52
1.99
2.6
1.8
29.05
29.36
s
0.15
55
375
10
39
2.62
1.96
1.3
1.4
—
—
—
0
0
99
784
1.39
1.90
4.7
3.4
0.00
0.01
estimate
0.74
36
246
9
34
2.70
1.88
2.3
3.6
—
—
—
0
0
191
1684
1.38
1.87
4.9
3.2
46.35
45.90
u/l
0.02
183
1590
83
640
1.41
1.86
2.7
2.8
320.58
337.56
umol/l
0.77
72
559
6
17
3.58
1.84
1.8
3.6
288.33
805.35
mg
—
6
17
103
825
1.38
1.84
3.9
2.0
115.01
211.52
u/l
2.92
96
784
15
73
2.11
1.84
1.4
1.2
—
—
—
0
0
21
116
1.87
1.84
3.0
2.5
—
—
—
0
0
35
226
1.62
1.81
4.0
4.6
1.00
0.81
%
—
10
75
144
1219
1.35
1.81
12.6
5.3
56.45
57.72
%
0.76
137
1167
42
284
1.56
1.80
1.6
1.4
—
—
—
0
0
50
352
1.51
1.79
1.4
1.2
—
—
—
0
0
25
148
1.75
1.77
2.8
2.4
0.56
0.64
%
0.67
25
148
13
61
2.18
1.74
1.4
1.2
—
—
—
0
0
7
24
2.96
1.73
1.0
1.0
—
—
—
0
0
33
213
1.62
1.71
4.0
4.7
0.00
0.11
%
—
8
61
58
426
1.45
1.68
1.7
1.7
—
—
—
0
0
124
1035
1.34
1.68
2.0
1.9
1.36
1.34
mmol/l
0.12
100
878
8
31
2.62
1.67
1.5
1.2
—
—
—
0
0
25
151
1.72
1.66
2.8
2.4
1.22
1.25
%
0.05
25
151
11
49
2.29
1.65
3.7
2.4
8.43
6.89
pmol/l
0.23
11
49
29
183
1.65
1.65
1.6
1.3
433.07
136.99
u/ml
1.16
12
75
32
208
1.60
1.62
3.9
4.5
0.50
0.59
%
—
10
63
8
32
2.54
1.61
1.1
1.2
—
—
—
0
0
39
267
1.53
1.59
7.2
3.0
7.38
7.39
ph
0.63
23
154
37
252
1.53
1.55
3.6
2.4
91.73
30.86
u/l
0.58
30
207
11
51
2.20
1.52
1.4
1.5
—
—
—
0
0
76
598
1.36
1.49
6.1
4.8
—
—
—
0
0
33
221
1.55
1.49
1.5
1.2
—
—
—
0
0
105
868
1.32
1.49
2.5
2.3
—
—
—
0
0
33
222
1.55
1.46
10.2
7.3
—
—
—
0
0
65
500
1.38
1.46
2.0
2.0
—
—
—
0
0
7
28
2.54
1.46
1.4
1.4
272.71
353.41
mu/l
—
7
22
7
28
2.54
1.46
1.6
2.0
90.37
90.91
%
—
7
28
5
16
3.16
1.44
1.4
1.7
73.80
72.50
umol/l
—
5
16
5
16
3.16
1.44
1.2
4.7
60.00
198.38
nmol/l
—
5
16
35
243
1.50
1.35
5.8
6.4
1.31
1.28
mmol/l
0.08
35
236
35
244
1.49
1.33
1.5
1.5
—
—
—
0
0
6
24
2.53
1.31
2.2
1.4
12.25
34.22
ng/l
—
6
24
15
84
1.83
1.29
1.3
1.5
—
—
—
0
0
18
107
1.73
1.29
1.1
1.1
—
—
—
0
0
41
298
1.44
1.27
6.0
2.6
7.01
7.39
umol/l
0.06
32
258
21
131
1.65
1.27
2.4
1.9
0.00
0.02
estimate
—
6
44
118
1014
1.27
1.21
2.6
2.1
—
—
—
0
0
6
26
2.33
1.19
1.2
1.2
—
—
—
0
0
5
20
2.52
1.15
1.0
1.2
—
—
—
0
0
5
20
2.52
1.15
5.0
1.3
13.06
10.52
%
—
5
20
17
103
1.69
1.15
1.1
1.1
—
—
—
0
0
68
548
1.31
1.13
2.0
1.8
476.93
40798676.68
pmol/l
0.76
57
451
7
30
2.36
1.13
3.6
2.0
—
—
—
0
0
32
228
1.45
1.11
7.6
3.7
—
—
—
0
0
66
532
1.31
1.10
5.9
5.0
2.45
2.77
ug/l
0.17
58
474
5
21
2.40
1.09
1.2
4.5
7.00
8.13
mmol/l
—
5
21
5
21
2.40
1.09
1.4
1.3
—
—
—
0
0
133
1171
1.25
1.08
2.4
2.1
94.85
97.76
pmol/l
0.28
79
618
244
2305
1.33
1.08
4.4
4.2
1.25
1.26
mmol/l
0.09
226
2111
140
1242
1.24
1.06
3.0
2.7
—
—
estimate
—
0
0
17
106
1.64
1.05
1.1
1.3
—
—
—
0
0
13
75
1.77
1.04
2.0
3.8
1.49
1.76
ratio
—
8
41
7
34
2.08
1.03
2.1
2.3
11.11
4.50
umol/l
—
7
27
19
123
1.58
1.02
8.3
12.7
15.89
16.07
%
0.10
19
115
7
134
0.51
1.01
2.1
1.9
—
—
—
0
0
15
92
1.66
0.99
1.1
1.4
76.65
249.78
miu/ml
—
6
46
5
23
2.19
0.98
1.2
3.0
—
—
—
0
0
9
50
1.82
0.97
1.7
2.7
18.33
16.10
%
—
9
50
0
31
0.00
0.97
0.0
1.1
—
—
—
0
0
6
117
0.50
0.96
3.7
4.2
—
—
—
0
0
42
324
1.35
0.95
3.4
3.1
3.76
6.54
e9/l
0.99
37
294
12
70
1.74
0.94
19.1
3.3
1.66
1.41
mg/l
0.55
12
59
62
508
1.28
0.92
4.7
3.9
791.00
260.65
ng/l
0.49
43
391
35
264
1.37
0.91
6.1
9.5
94.72
95.96
%
0.61
35
255
30
221
1.40
0.90
4.7
4.9
0.00
0.22
%
—
6
59
8
44
1.84
0.86
4.1
17.2
11.00
11.53
mmol/l
—
8
36
8
44
1.84
0.86
4.1
17.2
106.38
104.19
mmol/l
—
8
36
22
154
1.46
0.86
3.0
3.3
4.34
4.47
pmol/l
0.31
17
136
19
129
1.51
0.85
3.1
4.2
37.02
36.92
°c
0.36
19
129
33
251
1.35
0.83
6.4
9.8
121.36
120.37
g/l
0.11
33
243
31
234
1.36
0.82
1.4
1.4
—
—
—
0
0
16
106
1.54
0.80
3.4
9.2
0.79
0.86
%
0.37
16
94
26
191
1.40
0.80
4.8
3.3
—
—
—
0
0
10
59
1.72
0.76
3.7
2.7
—
—
—
0
0
5
24
2.10
0.75
1.2
1.2
—
—
—
0
0
40
319
1.29
0.74
3.4
3.0
0.62
0.86
ug/l
1.30
25
211
5
25
2.02
0.73
1.4
1.1
—
—
—
0
0
12
77
1.58
0.69
8.7
10.5
—
—
—
0
0
5
27
1.87
0.68
1.6
1.5
—
—
—
0
0
55
462
1.23
0.68
1.9
1.8
1186.08
1216.54
nmol/l
0.11
48
339
73
632
1.21
0.67
5.7
4.0
1.02
1.02
kg/l
0.16
46
428
31
243
1.31
0.66
1.8
1.4
—
—
—
0
0
53
445
1.23
0.66
4.0
2.9
3.89
3.42
e6/l
0.11
28
201
5
29
1.74
0.64
1.2
1.1
—
—
—
0
0
8
49
1.65
0.62
1.3
1.1
—
—
—
0
0
5
30
1.68
0.61
2.2
1.4
—
—
—
0
0
16
220
0.71
0.61
1.3
1.3
—
—
—
0
0
22
167
1.34
0.58
5.6
9.5
24.42
24.58
mmol/l
0.08
22
158
33
266
1.27
0.58
2.2
2.0
0.00
0.05
estimate
—
6
57
8
55
1.47
0.56
5.3
3.1
0.90
0.87
nmol/l
—
8
45
12
82
1.48
0.55
3.2
2.8
—
—
—
0
0
15
108
1.41
0.54
1.6
1.7
—
—
—
0
0
40
334
1.23
0.53
1.3
1.3
—
—
—
0
0
9
63
1.44
0.53
1.0
1.7
—
—
—
0
0
15
109
1.40
0.52
1.7
1.6
0.65
0.33
mg/l
—
6
47
14
101
1.41
0.50
2.6
2.0
13966.50
6216.21
u/l
—
5
37
20
154
1.32
0.50
3.5
7.6
—
—
—
0
0
7
47
1.50
0.48
1.0
1.8
—
—
—
0
0
36
303
1.21
0.46
6.1
8.7
7.40
7.41
ph
0.30
24
187
16
121
1.34
0.45
3.6
8.5
1.38
1.58
%
0.69
16
109
31
259
1.22
0.42
1.8
1.8
—
—
—
0
0
10
70
1.44
0.42
1.2
2.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
112.72
—
0
15
0
17
0.00
0.41
0.0
10.2
—
0.72
—
0
17
109
1012
1.12
0.40
5.6
3.8
30.40
69.44
ng/l
0.61
74
735
7
104
0.67
0.40
1.0
1.5
—
—
—
0
0
5
35
1.44
0.39
2.8
3.1
—
—
—
0
0
29
245
1.20
0.37
4.3
3.0
78.67
70.52
e9/l
0.54
23
195
6
42
1.44
0.35
1.3
1.0
—
—
—
0
0
6
44
1.37
0.34
1.2
1.9
—
—
—
0
0
6
44
1.37
0.34
1.3
1.5
24.63
21.02
u/l
—
6
36
10
74
1.36
0.32
2.9
2.1
—
—
—
0
0
8
65
1.24
0.27
1.5
1.3
—
—
—
0
0
6
81
0.74
0.24
1.5
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
4.3
—
49.23
—
0
11
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
0.50
—
0
10
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
32
288
1.12
0.21
2.8
4.6
10.52
25.98
ug/l
0.48
24
242
0
13
0.00
0.21
0.0
1.1
—
37.95
—
0
13
0
14
0.00
0.20
0.0
1.3
—
6.11
—
0
14
27
244
1.12
0.17
2.0
2.5
5.91
6.23
ph
0.67
17
162
8
68
1.18
0.16
1.6
1.1
—
—
—
0
0
8
72
1.11
0.16
1.8
2.5
8.08
8.28
kpa
—
8
72
9
82
1.10
0.15
1.0
1.5
—
—
—
0
0
7
87
0.80
0.14
1.3
2.4
24.30
24.64
mmol/l
—
7
87
26
282
0.91
0.12
1.8
1.9
—
—
—
0
0
82
792
1.05
0.11
2.0
1.7
17.83
20.96
nmol/l
1.51
75
667
10
87
1.15
0.09
1.0
1.1
0.92
0.86
g/l
—
10
87
5
47
1.06
0.09
1.0
1.0
—
—
—
0
0
19
175
1.09
0.08
1.2
1.3
—
—
—
0
0
32
304
1.06
0.07
6.6
8.7
5.18
5.14
kpa
0.10
32
289
32
304
1.06
0.07
6.7
8.7
11.30
12.62
kpa
0.95
32
291
7
85
0.82
0.07
1.6
2.0
42.29
311.29
ug/l
—
7
79
22
234
0.94
0.06
2.8
4.4
7.33
7.37
ph
0.42
14
172
9
101
0.89
0.06
1.0
1.5
—
—
—
0
0
9
102
0.88
0.06
1.0
1.5
—
—
—
0
0
9
102
0.88
0.06
1.0
1.5
—
—
—
0
0
17
175
0.97
0.00
3.5
2.8
47.00
56.87
u/ml
0.14
17
170
76
765
0.99
0.00
1.4
1.5
—
—
—
0
0
95
945
1.01
0.00
3.6
3.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
6.2
—
24.20
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.03
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
90.67
—
0
6
0
9
0.00
-0.00
0.0
1.3
—
177.20
—
0
9
9
96
0.94
-0.00
1.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
74
0.94
-0.00
8.7
4.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
86
0.93
-0.00
1.0
1.1
1.39
1.57
g/l
—
8
86
0
9
0.00
-0.00
0.0
1.3
—
60.56
—
0
9
5
56
0.89
-0.00
1.2
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_DACRYOADENITIS and mortality.

Females

Parameter HR [95% CI] p-value
H7_DACRYOADENITIS 1.049 [0.86, 1.27] 0.633
Birth year 0.995 [0.99, 1.0] 0.239

During the follow-up period (1.1.1998 — 31.12.2019), 219 out of 1134 females with H7_DACRYOADENITIS died.

Males

Parameter HR [95% CI] p-value
H7_DACRYOADENITIS 1.041 [0.76, 1.42] 0.798
Birth year 0.984 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 509 males with H7_DACRYOADENITIS died.

Mortality risk

Mortality risk for people of age

years, who have H7_DACRYOADENITIS.

N-year risk Females Males
1 0.087% 0.212%
5 0.568% 1.1%
10 1.448% 2.794%
15 2.876% 5.216%
20 5.457% 8.913%

Relationships between endpoints

Index endpoint: H7_DACRYOADENITIS – Dacryoadenitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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