skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
731 |
4. Check minimum number of eventsNone |
731 |
5. Include endpointsNone |
731 |
6. Filter based on genotype QC (FinnGen only) |
663 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L85
- Name in latin
- Xerosis cutis
Similar endpoints
↥List of similar endpoints to
Xerosis cutis
based on the number of shared cases.
Similar with more cases:
- Other epidermal thickening
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2572 | 1334 | 1230 |
| Only index persons | 2357 | 1230 | 1127 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 68.29 | 67.94 | 68.83 |
| Only index persons | 68.76 | 68.34 | 69.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 663 | 336 | 327 |
| Unadjusted period prevalence (%) | 0.13 | 0.12 | 0.15 |
| Median age at first event (years) | 70.34 | 67.87 | 72.87 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 679
- Matched controls
- 6790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L85.3
ICD-10 Finland
Xerosis cutis
+∞
307.7
679
19
E0000UV, ,
ATC
14.4
193.7
578
1934
TQW80
NOMESCO Finland
Local dermatologic skincare
27.4
146.4
103
44
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.9
111.2
180
295
L30.9
ICD-10 Finland
Dermatitis, unspecified
5.2
95.4
291
855
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
12.1
94.2
101
97
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
32.0
85.3
56
19
R4180
NOMESCO Finland
Podiatric therapy
27.5
83.8
58
23
L84
ICD-10 Finland
Corns and callosities
12.3
80.5
84
77
D07AC01
ATC
betamethasone; topical
4.3
76.2
398
1696
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
19.1
66.0
53
30
L30.4
ICD-10 Finland
Erythema intertrigo
17.7
64.8
54
33
L57.0
ICD-10 Finland
Actinic keratosis
4.7
61.8
177
476
D07AB02
ATC
hydrocortisone butyrate; topical
3.5
56.9
316
1338
L85.89
ICD-10 Finland
Other specified epidermal thickening
+∞
54.9
52
*
L29.9
ICD-10 Finland
Pruritus, unspecified
8.9
49.9
65
80
D02AE01
ATC
carbamide; topical
5.6
49.3
102
206
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
4.0
47.9
168
518
L30.8
ICD-10 Finland
Other specified dermatitis
9.2
46.2
58
68
D07AB08
ATC
desonide; topical
4.1
43.8
140
402
E000001, ,
ATC
3.4
43.7
209
786
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
3.6
40.6
168
574
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
4.3
38.5
110
289
L82
ICD-10 Finland
Seborrhoeic keratosis
3.2
37.3
187
716
L29
ICD-10 Finland
Pruritus
11.4
35.8
38
35
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.6
35.8
94
231
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.4
35.2
154
541
L04AA06
ATC
mycophenolic acid; systemic
11.5
33.1
35
32
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.8
33.0
222
993
H02AB06
ATC
prednisolone; systemic
2.6
32.1
401
2423
L30.3
ICD-10 Finland
Infective dermatitis
6.2
32.0
57
99
S18
ICPC
Laceration/cut
2.6
31.5
405
2473
SPAT1153
SPAT
Removal of sutures
2.6
31.2
291
1526
R06AX27
ATC
desloratadine; oral
2.7
30.6
232
1098
D07AA02
ATC
hydrocortisone; topical
3.1
29.4
143
531
D07BA04
ATC
hydrocortisone and antiseptics; topical
3.7
29.2
104
318
S97
ICPC
Chronic ulcer skin
4.3
28.8
79
200
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.7
28.7
103
316
B35.3
ICD-10 Finland
Tinea pedis
5.2
28.2
61
127
D07AD01
ATC
clobetasol; topical
3.0
28.1
155
617
SPAT1149
SPAT
Suture or treatment of traumatic wound
3.1
28.1
139
521
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.2
28.0
131
475
XQ848
NOMESCO Finland
Dermatological photography
6.4
27.5
47
78
D02AX
ATC
Other emollients and protectives
6.7
27.2
44
69
D07AC13
ATC
mometasone; topical
2.5
27.2
247
1263
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
6.8
26.3
42
65
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
25.8
305
1745
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
25.8
141
557
SPAT1301
SPAT
No procedures
2.4
25.1
280
1558
L50.3
ICD-10 Finland
Dermatographic urticaria
8.1
24.9
34
44
-, ,
ICD-10 Finland
6.4
24.4
41
67
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
23.9
408
2694
SPAT1312
SPAT
General health counselling
2.3
23.6
260
1431
L20.0
ICD-10 Finland
Besnier prurigo
3.9
23.1
71
195
R06AE07
ATC
cetirizine; oral
2.2
22.9
318
1920
A46
ICD-10 Finland
Erysipelas
2.7
22.7
143
606
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
22.4
255
1416
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.7
22.4
54
123
UJF32
NOMESCO Finland
Coloscopy
2.3
22.3
233
1248
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.4
21.8
32
45
E000006, ,
ATC
3.7
21.3
73
216
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
5.0
21.1
47
100
J01DB01
ATC
cefalexin; oral
2.9
20.8
591
4725
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
8.5
20.6
27
33
B35.1
ICD-10 Finland
Tinea unguium
3.5
20.5
76
237
J01MA02
ATC
ciprofloxacin; systemic
2.1
20.4
312
1933
R60.0
ICD-10 Finland
Localized oedema
2.6
20.1
132
568
C03CA01
ATC
furosemide; systemic
2.2
20.1
281
1678
B07.9
ICD-10 Finland
Verruca simplex
4.8
19.9
46
101
TK800
NOMESCO Finland
Hemodialysis
7.6
19.6
28
38
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.2
19.5
54
137
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
4.6
19.5
47
107
E000003, ,
ATC
4.4
19.4
50
120
E000002, ,
ATC
3.0
19.3
95
351
E000007, ,
ATC
3.9
19.0
59
163
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.3
18.9
186
962
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
7.0
18.8
29
43
D05BB02
ATC
acitretin; oral
6.4
18.6
31
50
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.6
18.5
30
47
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
18.4
193
1022
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.3
18.1
71
229
SPAT1249
SPAT
Treatment-related counselling outside office
2.0
18.0
302
1912
H02AB04
ATC
methylprednisolone; systemic
2.5
17.9
126
559
SPAT1263
SPAT
Sampling
2.0
17.4
321
2094
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.0
16.7
321
2115
L30.0
ICD-10 Finland
Nummular dermatitis
4.0
16.5
48
126
NH3BG
NOMESCO Finland
MRI of foot
19.1
16.1
24
13
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.0
15.8
279
1778
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
4.5
15.1
37
85
J01FF01
ATC
clindamycin; systemic
2.0
15.0
202
1166
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
5.0
14.9
32
66
D07BC01
ATC
betamethasone and antiseptics; topical
2.5
14.8
102
446
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.1
14.7
63
214
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
14.7
233
1423
SPAT1255
SPAT
Intravenous administration of medicine
3.1
14.7
66
231
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.0
14.5
235
1444
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.5
14.5
36
84
127
Kela drug reimbursment
Transplant complication
11.7
14.4
26
23
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.6
14.4
90
376
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.5
14.3
28
53
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
5.5
14.3
28
53
L04AD01
ATC
ciclosporin; systemic
6.3
14.3
24
39
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
14.1
208
1236
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.6
14.1
87
361
SPAT1254
SPAT
Administration of medicine
2.2
14.0
131
655
L04AX01
ATC
azathioprine; systemic
4.0
14.0
40
104
XQ802
NOMESCO Finland
Epicutan test
4.0
13.8
40
105
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.4
13.6
106
490
RJ190, ,
NOMESCO Finland
142.7
13.5
14
*
S29
ICPC
Skin symptom/complaint other
2.1
13.5
165
915
SPAT1260
SPAT
Consultation of another employee
2.1
13.5
144
759
Z94.0
ICD-10 Finland
Kidney transplant status
18.7
13.4
20
11
D01AE16
ATC
amorolfine; topical
2.4
13.4
105
487
RJ410, ,
NOMESCO Finland
40.9
13.2
16
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
13.2
312
2151
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
13.1
90
393
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.5
13.1
92
406
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
13.3
13.0
22
17
SPAT1101
SPAT
Orthostatic test
3.4
13.0
49
154
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
12.9
319
2224
M79.6
ICD-10 Finland
Pain in limb
1.8
12.9
317
2206
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
12.8
107
509
SPAT1210
SPAT
Application of cast or individual aid
3.5
12.8
44
130
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.9
12.8
63
232
N02BE01
ATC
paracetamol; systemic, rectal
2.8
12.8
623
5437
SPAT1325
SPAT
Vaccination
1.8
12.7
265
1752
SPAT1310
SPAT
Counselling related to known health issue
1.9
12.6
233
1484
L71.8
ICD-10 Finland
Other rosacea
6.3
12.5
21
34
SPAT1216
SPAT
Assessment of functional ability
2.1
12.3
142
769
RJ421, ,
NOMESCO Finland
38.3
12.2
15
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.4
12.2
95
438
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
21.7
12.1
17
8
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.8
12.0
281
1915
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.5
12.0
80
344
D07CC01
ATC
betamethasone and antibiotics; topical
2.3
11.8
102
492
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
30.6
11.7
15
5
A02BC02
ATC
pantoprazole; systemic
1.8
11.7
477
3815
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
5.4
11.6
23
44
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
5.0
11.5
25
52
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.2
11.5
31
77
L85.9
ICD-10 Finland
Epidermal thickening, unspecified
+∞
11.5
11
*
AA1AD
NOMESCO Finland
CT of head and brain
1.8
11.4
237
1556
D07XC01
ATC
betamethasone; topical
2.3
11.3
97
466
NHQ40
NOMESCO Finland
Amputation of toe
9.8
11.3
22
23
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
2.6
11.3
69
284
A41.8
ICD-10 Finland
Other specified sepsis
5.0
11.3
24
49
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
11.2
144
807
R50.9
ICD-10 Finland
Fever, unspecified
2.1
11.2
118
616
P01AB01
ATC
metronidazole; oral, rectal
1.8
11.2
268
1832
L29.8
ICD-10 Finland
Other pruritus
8.8
11.1
23
27
R01AD58
ATC
fluticasone, combinations; nasal
1.9
11.1
156
903
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.7
11.0
62
245
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.3
10.9
92
439
NH3CG
NOMESCO Finland
Extensive MRI of foot
12.2
10.9
19
16
N03AX12
ATC
[U] gabapentin; oral
2.0
10.8
128
698
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
10.7
120
641
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
10.7
254
1727
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.9
10.6
31
82
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.9
10.5
23
48
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
14.5
10.5
17
12
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
10.5
219
1431
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
111.7
10.4
11
*
RJ511, ,
NOMESCO Finland
+∞
10.4
10
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
10.4
250
1703
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
3.9
10.3
30
79
XQ845
NOMESCO Finland
Dermatoscopy
4.7
10.3
24
53
L24.8
ICD-10 Finland
Irritant contact dermatitis due to other agents
23.8
10.3
14
6
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.2
10.3
42
139
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
10.2
158
941
L89
ICD-10 Finland
Decubitus ulcer and pressure area
13.4
10.2
17
13
SPAT1229
SPAT
Assessment of need for aid
2.5
10.2
67
286
B01AC04
ATC
clopidogrel; oral
1.9
10.2
146
849
S06
ICPC
Rash localized
2.8
10.1
51
190
C01DA14
ATC
isosorbide mononitrate; oral
1.9
10.1
142
820
SPAT1285
SPAT
Provision of consultation response
2.9
10.1
47
168
RJ411, ,
NOMESCO Finland
14.9
10.0
16
11
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.2
10.0
87
420
H3603, E103,
ICD-10 Finland
40.7
10.0
12
*
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
17.0
9.9
15
9
L17
ICPC
Foot/toe symptom/complaint
1.7
9.9
223
1487
J01MA14
ATC
moxifloxacin; systemic
2.3
9.9
75
342
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
20.4
9.8
14
7
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
9.8
90
444
SPAT1324
SPAT
Screening procedure
2.2
9.8
93
465
N02AX02
ATC
tramadol; systemic, rectal
1.7
9.8
301
2182
D06BB10
ATC
imiquimod; topical
2.8
9.7
51
194
R03BB04
ATC
tiotropium bromide; inhalant
2.1
9.7
95
480
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
3.1
9.7
41
138
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
4.3
9.7
25
60
R06.0
ICD-10 Finland
Dyspnoea
1.7
9.7
214
1418
M25.5
ICD-10 Finland
Pain in joint
1.7
9.6
224
1505
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
9.5
108
577
D01BA02
ATC
terbinafine; oral
1.8
9.5
187
1196
M54.5
ICD-10 Finland
Low back pain
1.7
9.5
248
1717
RJ422, ,
NOMESCO Finland
101.4
9.4
10
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
9.4
94
479
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
9.4
297
2162
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
9.2
279
2004
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
4.0
9.2
26
67
R13
ICD-10 Finland
Dysphagia
2.4
9.2
62
268
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.4
9.1
32
96
ZXC50
NOMESCO Finland
Cryotherapy
3.4
9.1
32
96
A02BC03
ATC
lansoprazole; oral
1.7
9.1
209
1395
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
15.8
9.1
14
9
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.7
9.0
48
185
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.7
8.9
28
78
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.3
8.9
34
108
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.5
8.9
59
253
C03DA01
ATC
spironolactone; oral
2.0
8.9
102
548
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
8.9
254
1796
M13.9
ICD-10 Finland
Arthritis, unspecified
2.4
8.8
62
273
N18.8
ICD-10 Finland
Other chronic renal failure
4.2
8.8
23
56
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.7
8.8
49
193
D06BX01
ATC
metronidazole; topical
2.2
8.7
80
394
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
50.7
8.7
10
*
NH3DG
NOMESCO Finland
Very extensive MRI of foot
50.7
8.7
10
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
8.7
150
921
A12AA04
ATC
calcium carbonate; oral
7.1
8.6
20
29
B03XA02
ATC
darbepoetin alfa; parenteral
4.1
8.6
23
57
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.0
8.6
38
132
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
8.5
200
1339
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
4.3
8.5
22
53
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
8.4
76
373
L28
ICD-10 Finland
Lichen simplex chronicus and prurigo
8.7
8.3
17
20
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.4
8.3
60
268
WZA90
NOMESCO Finland
Other medical or dental certificate
1.8
8.2
159
1007
V03AE01
ATC
polystyrene sulfonate; oral
7.7
8.2
18
24
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
4.8
8.2
18
38
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
8.1
145
898
PD4CC
NOMESCO Finland
Very extensive arterigography of lower extremity with X-ray
9.1
8.1
16
18
Z49.1
ICD-10 Finland
Extracorporeal dialysis
10.2
8.1
15
15
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.2
8.0
21
51
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
4.2
8.0
21
51
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
8.0
89
471
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.3
8.0
59
265
L01BA01
ATC
methotrexate; systemic
3.5
8.0
27
79
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
8.0
78
394
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.7
7.9
42
161
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.2
7.9
31
100
L04AD02
ATC
tacrolimus; systemic
13.2
7.9
13
10
K59.09
ICD-10 Finland
Constipation, unspecified
2.3
7.9
64
300
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
7.8
127
763
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.1
7.8
75
376
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
7.8
451
3738
J02AC01
ATC
fluconazole; systemic
1.6
7.8
226
1593
SPAT1211
SPAT
Application of soft bandage
2.2
7.7
69
336
J30.0
ICD-10 Finland
Vasomotor rhinitis
3.4
7.7
27
81
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
7.6
62
291
J05AB11
ATC
valaciclovir; oral
1.9
7.6
108
622
SPAT1053
SPAT
Memory test
1.8
7.6
123
738
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
12.0
7.6
13
11
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
7.6
193
1315
D05AX52
ATC
calcipotriol, combinations; topical
2.7
7.5
39
148
N03AX16
ATC
[U] pregabalin
1.7
7.5
157
1015
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.6
7.5
227
1615
K07.60
ICD-10 Finland
Snapping jaw
2.8
7.4
38
143
A98
ICPC
Health maint/preventive medicine
2.7
7.4
646
5978
A41.9
ICD-10 Finland
Sepsis, unspecified
3.0
7.4
33
115
C08CA05
ATC
nifedipine; systemic
2.4
7.4
50
216
I20.09
ICD-10 Finland
Unstable angina
2.3
7.4
54
242
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.9
7.4
34
121
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
2.8
7.4
37
138
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
7.4
291
2199
K30
ICD-10 Finland
Functional dyspepsia
2.0
7.3
82
435
F01
ICPC
Eye pain
3.3
7.3
27
84
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
7.3
127
778
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
9.5
7.3
14
15
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
+∞
7.3
7
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
7.3
125
763
L04AX03
ATC
methotrexate; systemic
2.1
7.3
67
331
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.3
7.3
54
244
C07AB07
ATC
bisoprolol; oral
1.5
7.2
356
2822
D11AH02
ATC
pimecrolimus; topical
20.3
7.1
10
5
J02AC02
ATC
itraconazole; systemic
1.8
7.1
112
665
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
7.1
116
697
J01CA04
ATC
amoxicillin; systemic
1.7
7.1
526
4571
SPAT1252
SPAT
Overall medication plan or its review
2.2
7.1
57
266
137
Kela drug reimbursment
Uraemia requiring dialysis
12.2
7.1
12
10
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
12.2
7.1
12
10
A07EC01
ATC
sulfasalazine; oral, rectal
2.3
7.1
55
253
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.3
7.1
55
253
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.9
7.1
96
545
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.3
7.1
54
247
A10AE04
ATC
insulin glargine; parenteral
2.0
7.1
75
391
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.4
7.0
46
196
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.4
7.0
46
196
L43.8
ICD-10 Finland
Other lichen planus
4.4
7.0
17
39
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.6
7.0
174
1175
UKC02
NOMESCO Finland
Cystoscopy
1.8
7.0
124
764
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
7.0
78
414
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.9
7.0
87
480
S19
ICPC
Skin injury other
2.8
7.0
34
125
L21
ICD-10 Finland
Seborrhoeic dermatitis
3.8
7.0
21
57
SPAT1262
SPAT
Handing over of treatment supplies
1.8
6.9
124
765
KMAK, ,
NOMESCO Finland
1.5
6.9
303
2332
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.2
6.9
56
262
R03DC03
ATC
montelukast; oral
1.8
6.9
108
640
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
13.9
6.9
11
8
B05DA
ATC
Isotonic solutions
13.9
6.9
11
8
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.3
6.9
25
77
L04AA01
ATC
[U] ciclosporin
6.8
6.8
16
24
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
2.5
6.8
41
168
R03BA08
ATC
ciclesonide; inhalant
2.2
6.8
59
285
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
16.9
6.8
10
6
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
6.7
88
493
S02
ICPC
Pruritus
2.8
6.7
33
122
R42
ICD-10 Finland
Dizziness and giddiness
1.6
6.7
170
1153
GD1AD
NOMESCO Finland
Thorax CT examination
2.3
6.7
52
240
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.7
6.7
35
134
D09AB01
ATC
zinc bandage without supplements; topical
5.6
6.6
18
33
J01DA01
ATC
[U] cefalexin
1.5
6.6
392
3209
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
6.6
407
3359
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.5
6.6
22
64
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
3.9
6.6
19
50
R03AK08
ATC
formoterol and beclometasone; inhalant
2.7
6.6
35
135
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.3
6.6
47
209
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.5
6.6
39
159
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
6.5
227
1656
L03
ICPC
Low back symptom/complaint
1.6
6.5
191
1340
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
6.5
115
707
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.2
6.5
25
80
B35.6
ICD-10 Finland
Tinea inguinalis [Tinea cruris]
3.6
6.5
21
60
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.6
6.5
21
60
C10AC01
ATC
colestyramine; oral
3.3
6.5
24
75
S01
ICPC
Pain/tenderness of skin
2.6
6.5
38
154
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
6.5
435
3651
J01AA04
ATC
lymecycline; systemic
1.9
6.5
80
440
J05AB01
ATC
aciclovir; systemic
1.7
6.5
142
927
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.7
6.4
136
878
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
6.4
98
576
R22.7
ICD-10 Finland
Localized swelling, mass and lump, multiple sites
70.5
6.4
7
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.0
6.4
68
354
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
6.4
187
1309
B05DB
ATC
Hypertonic solutions
14.5
6.4
10
7
Z49.2
ICD-10 Finland
Other dialysis
14.5
6.4
10
7
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.0
6.4
72
383
SPAT1167
SPAT
Insertion of urinary catheter
2.9
6.4
30
108
R01AD12
ATC
fluticasone furoate; nasal
1.6
6.4
180
1250
L88
ICPC
Rheumatoid/seropositive arthritis
2.8
6.4
31
114
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
6.4
130
832
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
8.3
6.4
13
16
K13.78
ICD-10 Finland
Other change in the oral mucosa
3.3
6.3
23
71
K59.0
ICD-10 Finland
Constipation
2.3
6.3
48
219
N18.0
ICD-10 Finland
End-stage renal disease
11.2
6.3
11
10
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
9.4
6.3
12
13
S21
ICPC
Skin texture symptom/complaint
1.8
6.3
107
650
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
3.1
6.3
26
87
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
18.2
6.3
9
5
L91.0
ICD-10 Finland
Hypertrophic scar
18.2
6.3
9
5
L85.81
ICD-10 Finland
Keratosis pilaris
+∞
6.3
6
*
J01AA02
ATC
doxycycline; systemic
1.6
6.3
507
4416
N05CF01
ATC
zopiclone; oral
1.5
6.2
219
1598
ND1AE
NOMESCO Finland
Wrist ultrasound examination
26.9
6.2
8
*
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
3.7
6.2
19
52
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
6.2
133
861
A10AE06
ATC
insulin degludec; parenteral
3.0
6.2
27
93
R03AC03
ATC
terbutaline; inhalant
1.9
6.2
85
483
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
2.5
6.2
37
151
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
3.6
6.2
20
57
L04AA13
ATC
[U] leflunomide
3.6
6.2
20
57
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
3.3
6.2
23
72
B86
ICD-10 Finland
Scabies
3.5
6.2
21
62
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
3.4
6.2
22
67
H53.1
ICD-10 Finland
Subjective visual disturbances
2.2
6.2
52
248
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.6
6.1
35
140
C02AC05
ATC
moxonidine; oral
2.4
6.1
41
177
L60.9
ICD-10 Finland
Nail disorder, unspecified
4.2
6.1
16
39
A10AB05
ATC
insulin aspart; parenteral
2.2
6.1
53
256
D11AH01
ATC
tacrolimus; topical
8.7
6.1
12
14
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
6.1
74
405
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.9
6.1
28
100
J01FA10
ATC
azithromycin; systemic
1.5
6.1
340
2733
A07AA02
ATC
nystatin; oral
2.3
6.1
44
197
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
3.5
6.0
20
58
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
10.1
6.0
11
11
L20.8
ICD-10 Finland
Other atopic dermatitis
5.3
6.0
17
33
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
6.0
79
443
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
216
695
4.09
59.14
17.5
7.2
—
—
—
0
0
135
369
4.32
45.22
1.3
1.2
212.74
213.78
u/ml
0.00
129
339
160
545
3.53
38.68
2.9
2.5
9.09
7.00
ug/l
0.26
145
481
515
3380
3.17
37.49
12.4
9.5
4.15
4.19
e9/l
0.15
489
2938
441
2761
2.70
33.25
6.5
4.8
34.72
35.40
g/l
1.88
419
2578
275
1416
2.58
30.46
8.3
4.2
1.02
1.02
kg/l
0.10
197
951
192
839
2.80
29.42
8.4
4.8
1.11
1.04
mmol/l
2.40
180
771
123
426
3.30
28.37
8.0
6.9
23.83
24.65
mmol/l
1.17
118
405
129
465
3.19
27.82
3.1
2.5
55.11
64.59
ml/min/173m2
2.42
71
203
143
549
3.03
27.65
2.2
3.3
65.20
66.81
g/l
2.03
132
508
327
1930
2.34
25.68
4.0
2.6
56.02
62.94
u/l
1.02
302
1799
574
4373
3.02
25.22
7.2
4.3
14.70
12.96
mm/h
1.80
553
4039
509
3655
2.57
25.21
7.4
5.1
6.77
6.70
mmol/l
0.31
485
3484
221
1111
2.47
24.85
3.6
2.4
11.73
12.91
umol/l
1.88
209
1027
469
3257
2.42
24.82
8.3
6.5
12.53
11.92
umol/l
0.20
454
3113
461
3210
2.36
23.73
7.3
3.9
0.00
5.03
estimate
0.80
62
696
294
1708
2.27
23.40
3.4
2.3
3.03
2.98
mg/l
0.14
267
1463
460
3227
2.32
22.85
7.3
4.0
0.00
0.46
estimate
0.51
56
660
204
1035
2.39
22.09
3.6
2.3
2.31
2.31
g/l
0.02
194
950
320
1958
2.20
22.06
2.7
2.2
287.07
292.74
u/l
0.01
305
1856
337
2106
2.19
22.02
5.0
3.2
2082.47
1317.07
ng/l
1.59
310
1829
304
1835
2.19
21.56
8.3
4.0
0.00
0.01
estimate
0.78
53
634
449
3168
2.23
21.26
7.2
3.9
0.00
0.00
estimate
-0.00
56
683
575
4528
2.76
20.96
12.9
8.1
82.52
79.53
u/l
0.69
561
4273
121
495
2.76
20.42
4.4
3.3
100.95
82.74
ng/l
1.38
112
423
161
760
2.47
20.26
6.1
4.0
232.77
245.98
u/l
1.11
153
719
71
214
3.59
20.13
2.1
1.7
6.93
9.56
iu/ml
0.19
23
47
161
764
2.45
20.00
6.5
8.3
1.58
1.10
mmol/l
1.04
120
643
527
4020
2.39
19.98
7.7
4.8
12.53
1910.79
e6/l
1.96
12
71
265
1552
2.16
19.92
4.2
2.7
359.44
349.74
umol/l
0.68
234
1341
392
2669
2.11
19.72
3.0
2.4
75.83
78.20
nmol/l
0.95
366
2371
162
776
2.43
19.68
6.7
8.2
4.96
5.13
kpa
1.19
155
747
162
777
2.42
19.62
6.7
8.2
11.40
11.97
kpa
0.87
153
751
371
2478
2.10
19.60
5.7
4.0
44.94
74.34
ng/l
0.58
299
1895
142
647
2.51
19.19
6.9
8.7
118.49
121.19
g/l
0.80
137
631
360
2399
2.07
18.90
7.3
3.9
0.00
0.02
estimate
1.63
44
564
422
2999
2.08
18.36
26.1
16.5
1.35
1.29
inr
1.10
369
2501
184
958
2.26
18.30
3.6
2.4
20.49
22.62
%
1.52
174
888
61
177
3.69
18.28
1.7
1.5
1.16
1.19
g/l
0.28
56
172
440
3182
2.09
18.16
11.7
6.9
1.20
1.21
mmol/l
3.38
408
2743
557
4425
2.44
18.05
5.3
4.3
15.21
14.91
pmol/l
2.09
521
3994
142
666
2.43
17.93
5.9
3.2
1.91
1.99
mmol/l
0.10
128
568
104
420
2.74
17.88
2.3
1.6
—
—
—
0
0
393
2754
2.01
17.38
4.3
3.0
144.40
134.99
ug/l
0.34
375
2544
406
2891
2.01
17.00
11.0
6.4
1.20
1.21
mmol/l
4.32
385
2663
203
1154
2.08
15.84
2.6
1.8
—
—
—
0
0
59
187
3.36
15.44
1.8
1.2
—
—
—
0
0
199
1144
2.05
14.93
1.8
1.8
1507.83
1182.14
nmol/l
3.20
157
874
323
2203
1.89
14.56
4.1
3.3
6.51
7.58
mmol/l
5.52
288
1835
161
867
2.12
14.32
2.4
1.8
—
—
—
0
0
391
2845
1.88
14.29
2.6
2.2
91.20
94.64
pmol/l
0.78
247
1523
105
474
2.44
14.23
1.6
1.5
—
—
—
0
0
322
2210
1.87
14.09
3.0
3.5
2.33
2.35
mmol/l
1.97
291
1976
235
1466
1.92
13.75
3.9
2.6
6.03
5.01
e6/l
0.45
226
1341
612
5268
2.64
13.42
6.9
5.4
2.01
1.99
mu/l
0.07
586
4823
126
637
2.20
13.06
2.8
2.4
71.05
69.38
e9/l
0.22
101
480
28
58
4.99
12.95
2.6
2.3
1248.39
1079.14
mg
0.17
28
58
288
1960
1.82
12.53
2.1
1.8
19.07
20.21
nmol/l
0.64
257
1654
37
100
3.86
12.26
9.0
4.8
374.25
287.30
iu/ml
—
8
10
148
816
2.04
12.18
2.6
1.8
—
—
—
0
0
218
1371
1.87
12.17
1.7
1.8
193846588.33
9494664.57
pmol/l
1.19
195
1127
178
1056
1.93
11.84
4.8
3.3
0.81
0.82
mmol/l
0.62
164
995
26
55
4.88
11.74
1.4
1.3
15701.94
258169.19
e6/l
1.10
18
36
634
5625
2.92
11.73
33.9
16.7
24.94
25.16
mg/l
0.05
571
4703
115
592
2.13
11.30
2.4
2.4
0.19
0.21
g/l
1.18
103
550
208
1320
1.83
11.11
2.4
1.7
1.16
1.43
mg/l
0.85
170
1038
76
331
2.46
11.06
1.6
1.5
—
—
—
0
0
205
1308
1.81
10.70
1.5
1.3
1.33
1.89
u/ml
0.35
56
340
651
5918
3.43
10.36
20.3
12.2
25.54
25.16
u/l
0.22
642
5737
370
2809
1.70
10.25
3.5
2.8
—
—
estimate
—
0
0
66
279
2.51
10.23
1.7
2.6
3.52
3.70
g/l
0.40
59
256
300
2155
1.70
10.21
4.8
4.1
20.67
7.81
mg/mmol
1.89
224
1331
608
5358
2.29
10.21
9.0
6.8
41.32
39.58
mmol/mol
3.21
587
4982
66
280
2.50
10.15
1.7
2.6
6.93
7.42
g/l
1.75
59
256
66
280
2.50
10.15
1.7
2.6
4.08
4.18
g/l
0.41
59
256
600
5279
2.17
9.80
5.6
4.4
1.33
1.27
mmol/l
0.96
556
4790
62
261
2.51
9.69
1.6
2.6
2.73
2.99
g/l
1.23
55
237
642
5823
2.88
9.65
38.6
20.5
4.03
3.99
mmol/l
2.94
634
5698
205
1342
1.76
9.65
2.8
3.1
2.45
2.45
mmol/l
0.02
189
1195
641
5814
2.83
9.55
38.6
20.3
139.14
139.63
mmol/l
4.26
634
5696
58
240
2.55
9.40
1.7
2.7
9.22
10.77
g/l
1.88
51
214
120
674
1.95
9.19
2.7
2.3
155.38
129.15
ug/g
0.39
93
530
404
3194
1.65
9.12
3.3
2.8
—
—
—
0
0
72
334
2.29
9.09
1.4
1.3
34.30
52.90
au/ml
—
5
32
41
144
2.97
9.06
2.2
2.5
277.97
48.11
ug/min
1.18
28
83
43
158
2.84
8.77
1.3
1.2
2.07
6.27
u/ml
—
6
23
56
238
2.47
8.59
2.4
2.9
—
—
—
0
0
27
77
3.61
8.32
1.0
1.2
1.51
1.52
g/l
0.05
27
71
44
171
2.68
8.09
1.6
1.3
—
—
—
0
0
623
5648
2.25
8.04
7.4
6.1
2.45
2.61
mmol/l
4.28
585
5195
656
6091
3.27
8.02
48.6
25.6
4.32
4.45
e12/l
7.42
651
5940
656
6093
3.26
7.98
49.1
25.8
131.15
134.13
g/l
5.26
651
6016
615
5553
2.14
7.94
6.6
5.3
4.33
4.53
mmol/l
5.01
573
5134
611
5515
2.08
7.71
6.3
5.1
1.42
1.46
mmol/l
1.25
569
5060
177
1174
1.69
7.70
1.5
1.5
2.52
2.55
g/l
0.08
116
690
36
130
2.87
7.60
1.7
1.4
—
—
—
0
0
74
375
2.09
7.50
2.5
2.6
19.70
15.16
au/ml
—
8
34
52
230
2.37
7.33
2.5
4.1
81.25
79.30
mg/l
0.02
47
200
52
231
2.35
7.26
2.5
4.1
32.63
49.51
mg/l
0.74
47
200
40
159
2.61
7.06
1.4
1.6
—
—
—
0
0
212
1501
1.60
7.03
3.3
2.4
—
—
—
0
0
24
72
3.42
6.89
1.3
1.4
—
—
—
0
0
38
150
2.62
6.80
1.4
1.2
—
—
—
0
0
28
94
3.06
6.72
1.6
1.3
146.17
164.76
au/ml
—
6
24
41
170
2.50
6.65
1.6
1.3
—
—
—
0
0
38
152
2.59
6.63
1.4
1.2
—
—
—
0
0
52
241
2.25
6.60
1.9
2.9
0.51
1.05
g/l
0.62
43
214
47
211
2.32
6.42
2.6
3.7
3.67
4.84
ratio
0.17
33
124
29
104
2.87
6.23
1.6
1.3
—
—
—
0
0
603
5505
1.85
6.07
7.1
5.4
6.19
5.99
mmol/l
2.03
575
5010
234
1747
1.52
5.95
6.1
4.8
22.12
21.71
%
0.17
124
890
436
3695
1.50
5.92
4.1
3.3
59.84
51.58
u/l
0.82
413
3456
25
85
3.02
5.90
8.5
5.6
12.66
12.22
mg/l
0.19
25
78
272
2099
1.49
5.88
5.0
3.4
39.40
106.12
e6/l
1.09
243
1631
97
587
1.76
5.78
2.0
2.0
365.57
391.61
nmol/l
0.63
91
546
43
196
2.27
5.69
1.8
2.9
0.00
0.00
g/l
-0.00
38
175
19
56
3.46
5.62
1.1
1.0
2.47
2.87
u/ml
0.06
12
28
33
135
2.52
5.53
2.9
2.0
575.20
6447.25
u/l
1.11
11
46
35
149
2.42
5.41
1.6
1.4
—
—
—
0
0
16
34
4.79
5.33
1.8
1.5
16.33
20.97
umol/l
0.27
16
29
159
1116
1.55
5.28
3.9
3.1
1.17
1.09
e6/l
0.13
115
611
18
54
3.40
5.19
1.1
1.1
1.30
5.82
u/ml
0.66
12
25
31
130
2.45
4.96
1.5
1.4
—
—
—
0
0
16
46
3.54
4.92
1.0
1.0
0.18
0.97
u/ml
—
8
14
171
1237
1.51
4.91
5.7
4.1
369.95
306.16
ng/l
0.09
134
998
49
258
1.97
4.53
1.1
1.0
—
—
—
0
0
46
237
2.01
4.51
1.4
1.4
—
—
—
0
0
26
106
2.51
4.43
1.2
1.3
329.00
269.75
u/ml
0.45
18
55
36
171
2.17
4.37
2.3
1.5
—
—
—
0
0
37
178
2.14
4.35
1.3
1.4
232.63
281.92
ug/g
0.69
22
113
105
700
1.59
4.32
3.5
2.8
7.66
7.94
umol/l
0.06
90
617
17
56
3.09
4.26
1.5
1.4
25.68
26.48
u/l
—
10
49
21
79
2.71
4.19
1.1
1.1
0.30
2.11
u/ml
2.01
12
44
46
246
1.93
4.08
2.7
1.8
—
—
—
0
0
142
1032
1.48
3.92
1.3
1.3
26.80
35.97
iu/ml
0.91
42
328
26
113
2.35
3.89
2.4
1.6
—
—
—
0
0
30
139
2.21
3.89
1.5
1.4
236.16
249.95
miu/ml
—
8
62
18
66
2.77
3.78
1.1
1.0
0.72
0.92
u/ml
—
10
33
42
224
1.93
3.77
2.3
1.6
—
—
—
0
0
17
61
2.83
3.71
2.7
1.7
—
—
—
0
0
28
129
2.22
3.69
1.6
1.4
—
—
—
0
0
18
67
2.73
3.68
2.6
1.6
—
—
—
0
0
16
56
2.90
3.65
1.1
1.2
—
—
—
0
0
11
26
4.28
3.52
1.1
1.0
1783.09
1410.81
miu/ml
0.36
11
26
33
166
2.04
3.50
2.1
1.5
—
—
—
0
0
32
160
2.05
3.45
1.5
1.5
—
—
—
0
0
99
695
1.50
3.23
1.6
1.4
—
—
—
0
0
223
1807
1.35
3.23
4.7
3.3
0.49
0.47
e6/l
0.06
190
1354
28
137
2.09
3.21
1.5
1.4
—
—
—
0
0
8
15
5.38
3.20
1.0
1.0
—
—
—
0
0
262
2178
1.33
3.18
6.1
6.0
1.80
2.52
ug/l
2.81
242
1941
15
55
2.77
3.17
2.9
1.6
—
—
—
0
0
15
55
2.77
3.17
2.9
1.6
—
—
—
0
0
15
55
2.77
3.17
2.9
1.6
—
—
—
0
0
16
61
2.66
3.15
3.6
2.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
37
202
1.88
3.14
6.3
2.7
0.33
0.39
iu/ml
0.48
18
115
129
959
1.43
3.13
1.3
1.3
12.58
13.19
u/ml
0.03
53
335
19
80
2.41
3.08
1.7
1.6
—
—
—
0
0
15
61
2.49
2.63
1.1
1.2
—
—
—
0
0
27
142
1.94
2.59
1.3
1.3
—
—
—
0
0
10
31
3.26
2.52
4.3
3.9
1.30
1.26
%
—
10
31
9
26
3.49
2.49
1.8
1.6
—
—
—
0
0
10
32
3.16
2.44
3.7
1.5
290.10
191.15
e6/l
—
10
26
12
46
2.64
2.37
1.2
1.1
—
—
—
0
0
12
46
2.64
2.37
1.2
1.1
—
—
—
0
0
10
33
3.06
2.36
2.9
1.4
469.70
529.36
e6/l
—
10
25
13
53
2.48
2.29
1.2
1.1
—
—
—
0
0
10
36
2.80
2.14
1.0
1.3
—
—
—
0
0
19
96
2.01
2.07
1.5
2.0
4.27
4.72
mmol/24h
0.21
19
84
6
15
4.03
2.04
1.0
1.1
—
—
—
0
0
16
76
2.13
2.04
1.3
1.2
3.00
1.85
u/ml
—
7
27
110
859
1.33
1.99
1.5
1.5
—
—
—
0
0
25
142
1.79
1.95
1.6
1.5
—
—
—
0
0
10
39
2.59
1.94
1.8
1.1
—
—
—
0
0
10
39
2.59
1.94
1.8
1.1
—
—
—
0
0
6
16
3.77
1.94
1.0
1.1
—
—
—
0
0
6
16
3.77
1.94
1.0
1.1
—
—
—
0
0
11
45
2.47
1.94
1.2
1.1
—
—
—
0
0
59
417
1.45
1.92
2.4
1.6
—
—
—
0
0
25
143
1.78
1.91
1.5
1.2
10.92
7.72
u/l
0.60
20
106
573
5456
1.32
1.89
27.8
16.7
71.39
77.65
ml/min/173m2
8.78
547
5068
14
65
2.18
1.89
2.2
1.8
—
—
—
0
0
12
52
2.33
1.88
1.2
1.1
—
—
—
0
0
48
327
1.50
1.87
3.2
3.3
4.07
4.43
pmol/l
1.39
40
292
9
34
2.67
1.87
1.6
1.9
84.70
81.97
ng/l
—
9
34
13
59
2.23
1.85
1.6
1.6
—
—
—
0
0
20
108
1.88
1.83
1.5
1.4
—
—
—
0
0
24
139
1.75
1.78
1.2
1.1
—
9.22
—
0
12
15
74
2.05
1.76
2.1
1.2
—
—
—
0
0
6
18
3.35
1.75
2.0
2.2
471.83
417.33
e6/l
—
6
12
7
24
2.94
1.72
1.0
1.1
—
—
—
0
0
7
24
2.94
1.72
1.0
1.1
—
—
—
0
0
5
13
3.87
1.72
1.2
1.3
—
—
—
0
0
15
76
2.00
1.65
2.1
1.3
—
—
—
0
0
15
76
2.00
1.65
2.1
1.3
—
—
—
0
0
7
26
2.71
1.58
1.3
1.3
—
—
—
0
0
7
26
2.71
1.58
5.3
3.1
88.00
105.08
%
—
7
26
225
1968
1.21
1.58
4.5
3.2
30.90
33.70
u/l
0.73
214
1853
87
681
1.32
1.57
3.7
4.7
13.04
26.48
ug/l
0.46
75
578
12
57
2.13
1.55
1.1
1.1
—
—
—
0
0
8
33
2.44
1.54
1.0
1.1
268.25
233.50
mg/l
—
8
28
5
15
3.35
1.52
1.0
1.2
—
—
—
0
0
5
15
3.35
1.52
1.0
1.1
—
—
—
0
0
14
72
1.96
1.49
1.2
1.1
—
—
—
0
0
78
608
1.32
1.46
1.6
1.8
1.64
1.56
%
0.26
67
524
7
28
2.52
1.45
1.3
1.2
—
—
—
0
0
14
73
1.94
1.44
2.2
1.3
—
—
—
0
0
14
73
1.94
1.44
2.2
1.3
—
—
—
0
0
12
59
2.05
1.44
1.1
1.1
—
—
—
0
0
5
16
3.14
1.44
1.0
1.3
—
—
—
0
0
48
348
1.41
1.41
1.5
1.2
170.45
128.57
u/ml
0.25
23
145
14
74
1.91
1.40
2.2
1.3
—
—
—
0
0
7
29
2.43
1.39
1.1
7.6
—
58.17
—
0
6
26
166
1.59
1.39
1.7
1.5
—
—
—
0
0
6
23
2.62
1.37
1.3
2.7
703.33
1254.57
u/ml
—
6
23
25
160
1.58
1.33
2.2
2.2
13.54
12.73
mg/l
0.15
25
147
23
145
1.61
1.30
3.8
1.9
2.51
4.39
iu/l
1.00
11
52
5
18
2.79
1.28
1.8
1.9
0.59
0.63
mmol/l
—
5
18
61
469
1.33
1.27
2.1
2.4
12.83
12.57
nmol/l
0.09
55
408
6
25
2.41
1.24
2.2
1.6
—
—
—
0
0
9
45
2.01
1.23
1.2
1.1
—
—
—
0
0
6
26
2.32
1.19
2.0
1.6
58.55
56.80
ug/l
—
6
26
11
57
1.95
1.17
1.5
1.7
51.37
49.99
ug/l
0.04
11
57
5
20
2.51
1.15
3.6
1.5
9.30
20.54
u/l
—
5
20
5
20
2.51
1.15
1.0
1.0
—
—
—
0
0
19
119
1.61
1.12
5.2
1.4
1.09
0.88
nmol/l
0.29
14
98
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
30
2.35
1.12
1.1
1.1
—
—
—
0
0
14
81
1.74
1.09
1.5
1.5
—
—
—
0
0
29
202
1.46
1.09
1.9
1.6
8.04
10.94
u/ml
—
8
41
8
41
1.96
1.09
1.5
2.2
13.63
13.20
%
—
8
41
7
32
2.20
1.08
1.0
1.5
—
—
—
0
0
7
32
2.20
1.08
1.0
1.5
—
—
—
0
0
13
74
1.77
1.07
1.2
1.2
14.20
7.41
u/ml
—
5
29
7
33
2.13
1.05
1.3
1.2
—
—
—
0
0
7
33
2.13
1.05
1.3
1.2
—
—
—
0
0
34
460
0.73
1.04
2.1
1.9
3.22
3.43
ratio
0.44
28
360
7
34
2.07
1.03
2.4
2.6
1.43
0.94
index
—
7
34
10
54
1.86
0.97
1.1
1.3
—
—
—
0
0
6
28
2.15
0.91
1.0
1.0
—
—
—
0
0
6
30
2.01
0.87
2.2
1.1
—
—
—
0
0
6
30
2.01
0.87
2.2
1.1
—
—
—
0
0
6
30
2.01
0.87
1.3
1.1
—
—
—
0
0
15
96
1.58
0.85
1.3
1.6
—
—
—
0
0
8
45
1.79
0.84
1.1
1.1
—
—
—
0
0
12
73
1.66
0.82
1.8
1.8
—
—
—
0
0
12
74
1.63
0.78
3.7
2.5
35.17
21.67
mg/l
—
6
29
9
55
1.64
0.73
1.2
1.2
10.67
11.30
u/l
—
9
50
8
136
0.58
0.73
1.3
1.1
1.44
1.56
g/l
—
8
136
18
125
1.45
0.73
1.7
1.4
—
—
—
0
0
18
125
1.45
0.73
1.7
1.4
—
—
—
0
0
25
332
0.74
0.72
1.5
1.7
3.01
3.42
mmol/l
0.94
17
238
5
26
1.93
0.70
4.6
1.7
—
—
—
0
0
5
26
1.93
0.70
4.6
1.7
—
—
—
0
0
5
27
1.86
0.68
4.6
1.7
—
—
—
0
0
5
27
1.86
0.68
1.4
1.9
36.14
41.33
g/l
—
5
27
38
471
0.80
0.67
2.9
2.2
—
—
—
0
0
5
28
1.79
0.66
1.2
1.7
3.36
8.31
nmol/l
—
5
22
5
30
1.67
0.61
1.4
1.3
179.74
153.13
pmol/l
—
5
30
13
88
1.49
0.61
1.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
389.46
—
0
13
6
35
1.72
0.58
3.0
3.7
101.00
148.43
nmol/l
—
6
35
8
55
1.46
0.56
1.4
1.3
80.88
41.18
u/l
—
8
47
6
37
1.63
0.55
1.8
1.6
96.17
86.35
umol/l
—
6
37
47
395
1.20
0.55
5.5
3.7
1.21
2.25
mmol/l
1.36
38
292
20
151
1.33
0.54
1.4
1.5
—
—
—
0
0
22
169
1.31
0.54
3.6
3.0
1.92
1.70
index
0.05
12
98
6
40
1.50
0.51
1.3
1.2
—
—
—
0
0
10
145
0.69
0.51
1.5
1.2
0.93
0.91
g/l
—
10
145
11
75
1.47
0.51
1.0
1.1
—
2.36
—
0
12
13
92
1.42
0.51
1.2
1.4
—
—
—
0
0
58
661
0.87
0.46
4.5
3.5
—
—
—
0
0
7
50
1.40
0.45
1.1
1.0
—
—
—
0
0
7
51
1.38
0.44
1.3
1.1
138.00
107.51
pmol/l
—
7
51
5
31
1.62
0.43
1.0
1.0
—
—
—
0
0
37
433
0.85
0.41
2.8
2.1
—
—
—
0
0
5
34
1.47
0.40
4.8
1.6
—
—
—
0
0
5
34
1.47
0.40
4.8
1.6
—
—
—
0
0
5
34
1.47
0.40
4.8
1.6
—
—
—
0
0
5
34
1.47
0.40
4.8
1.6
—
—
—
0
0
5
35
1.43
0.39
1.6
1.7
5.80
8.19
u/l
—
5
28
96
1046
0.90
0.38
4.4
3.2
2.04
2.36
e6/l
0.20
57
536
11
80
1.38
0.38
1.5
1.3
6.46
6.52
mmol/l
0.04
11
75
5
36
1.39
0.38
1.0
1.8
—
—
—
0
0
84
769
1.11
0.35
6.1
5.1
33.39
32.23
%
0.46
61
503
27
228
1.19
0.34
1.7
1.7
0.34
0.32
mg/l
0.06
17
103
16
127
1.27
0.33
1.7
2.0
191.44
212.32
pmol/l
0.42
16
116
11
85
1.30
0.28
3.9
3.5
—
—
—
0
0
10
78
1.29
0.24
1.1
1.0
—
—
—
0
0
5
38
1.32
0.23
1.8
2.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
178
1716
1.05
0.21
4.8
3.4
0.25
0.06
estimate
0.35
40
536
6
50
1.20
0.19
1.3
1.4
—
—
—
0
0
6
53
1.13
0.18
1.5
1.6
—
—
—
0
0
13
111
1.17
0.16
1.8
1.5
—
—
—
0
0
248
2425
1.04
0.15
2.1
1.9
1.32
1.33
mmol/l
0.07
220
1997
28
258
1.09
0.12
2.4
2.3
—
—
—
0
0
125
1286
0.97
0.11
3.2
3.4
0.59
0.79
ug/l
4.15
96
866
18
165
1.09
0.09
1.2
1.3
—
—
—
0
0
13
144
0.90
0.08
1.9
2.0
54.52
59.02
%
0.39
13
144
22
208
1.06
0.05
2.3
2.3
—
—
—
0
0
58
565
1.03
0.05
4.2
2.4
30.08
32.35
u/l
0.39
53
465
15
146
1.03
0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
89.14
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.4
—
77.10
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_XEROSCUT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_XEROSCUT | 1.673 [1.27, 2.2] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.023 |
During the follow-up period (1.1.1998 — 31.12.2019), 223 out of 875 females with L12_XEROSCUT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_XEROSCUT | 2.043 [1.5, 2.79] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 277 out of 820 males with L12_XEROSCUT died.
Mortality risk
Mortality risk for people of age
years, who have L12_XEROSCUT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.113% | 0.411% |
| 5 | 0.808% | 2.582% |
| 10 | 2.019% | 6.221% |
| 15 | 3.996% | 12.021% |
| 20 | 7.158% | 19.296% |
Relationships between endpoints
↥Index endpoint: L12_XEROSCUT – Xerosis cutis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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