No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
486 |
4. Check minimum number of eventsNone |
486 |
5. Include endpointsNone |
486 |
6. Filter based on genotype QC (FinnGen only) |
427 |
Control definitions (FinnGen only)
- Control exclude
- M13_DORSOPATHY
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M40-M43
- Name in latin
- Osteochondrosis spinalis
Similar endpoints
↥List of similar endpoints to
Spinal osteochondrosis
based on the number of shared cases.
Similar with more cases:
- Deforming dorsopathies
- Dorsopathies
- Diseases of the musculoskeletal system and connective tissue
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4271 | 1626 | 2630 |
| Only index persons | 4030 | 1537 | 2493 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.05 | 0.07 |
| Only index persons | 0.08 | 0.06 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 35.52 | 48.47 | 27.38 |
| Only index persons | 33.50 | 46.39 | 25.56 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 427 | 197 | 230 |
| Unadjusted period prevalence (%) | 0.09 | 0.07 | 0.11 |
| Median age at first event (years) | 40.65 | 42.99 | 38.65 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 441
- Matched controls
- 4410
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M42.0
ICD-10 Finland
Juvenile osteochondrosis of spine
7393.3
305.2
258
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
71.7
230.4
128
25
M48.0
ICD-10 Finland
Spinal stenosis
132.9
217.7
110
11
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
53.2
147.4
86
20
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
34.3
143.5
95
35
M42.1
ICD-10 Finland
Adult osteochondrosis of spine
+∞
99.9
92
*
N03AX16
ATC
[U] pregabalin
8.2
95.4
165
298
N03AX12
ATC
[U] gabapentin; oral
9.4
85.9
121
171
M54.5
ICD-10 Finland
Low back pain
6.1
79.8
233
685
M54.9
ICD-10 Finland
Dorsalgia, unspecified
9.4
77.8
107
146
M54.4
ICD-10 Finland
Lumbago with sciatica
7.9
70.9
115
189
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
9.2
68.5
93
124
N02AX02
ATC
tramadol; systemic, rectal
4.8
59.7
246
914
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
19.1
59.2
48
28
M54.6
ICD-10 Finland
Pain in thoracic spine
10.1
58.1
71
82
M42.9
ICD-10 Finland
Spinal osteochondrosis, unspecified
+∞
57.6
54
*
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
313.9
55.5
55
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
10.8
54.6
63
67
7320A
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of spine[MORBUS SCHEUERMANN]
+∞
53.2
50
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
140.6
47.9
50
*
N06AX21
ATC
duloxetine; oral
6.1
44.2
88
174
M03BC01
ATC
orphenadrine (citrate); systemic
4.4
42.5
142
433
M54.3
ICD-10 Finland
Sciatica
11.8
38.8
41
38
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
14.1
36.1
34
26
L03
ICPC
Low back symptom/complaint
3.6
34.5
164
627
M03BX02
ATC
tizanidine; oral
3.5
32.9
312
1796
M47.9
ICD-10 Finland
Spondylosis, unspecified
122.5
32.1
34
*
M47.82
ICD-10 Finland
Other spondylosis, cervical region
44.7
30.4
37
9
N02BF01
ATC
gabapentin; oral
5.6
28.9
59
118
L02
ICPC
Back symptom/complaint
4.4
28.6
82
218
M01AH01
ATC
celecoxib; oral
4.0
28.4
95
283
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.0
28.3
227
1154
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
149.1
26.9
28
*
L86
ICPC
Back syndrome with radiating pain
7.4
25.9
39
57
M79.6
ICD-10 Finland
Pain in limb
2.9
25.7
219
1133
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
53.4
25.6
30
6
M43.1
ICD-10 Finland
Spondylolisthesis
38.2
25.6
32
9
N06AA09
ATC
amitriptyline; systemic
5.3
25.3
55
116
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
36.9
24.6
31
9
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
59.6
24.3
28
5
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.0
23.9
142
602
M53.1
ICD-10 Finland
Cervicobrachial syndrome
4.3
23.7
67
175
M54.2
ICD-10 Finland
Cervicalgia
5.3
23.3
50
104
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
+∞
23.1
22
*
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
126.6
22.8
24
*
M40.2
ICD-10 Finland
Other and unspecified kyphosis
+∞
22.1
21
*
N06AX11
ATC
mirtazapine; oral
2.7
22.0
179
889
M01AH02
ATC
rofecoxib; oral
4.1
22.0
67
185
Z01.8
ICD-10 Finland
Other specified special examinations
3.0
21.7
123
504
R52.2
ICD-10 Finland
Other chronic pain
7.7
21.5
31
43
M01AE03
ATC
ketoprofen; systemic, rectal
2.7
20.8
169
835
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
19.5
20.7
31
17
A02BC05
ATC
esomeprazole; systemic
2.6
20.4
191
1009
A01
ICPC
Pain general/multiple sites
4.0
20.3
63
176
M01AB55
ATC
diclofenac, combinations; oral
6.3
19.9
35
60
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
+∞
19.9
19
*
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
+∞
19.9
19
*
G47.3
ICD-10 Finland
Sleep apnoea
2.8
19.7
134
603
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.3
19.6
54
138
R07.4
ICD-10 Finland
Chest pain, unspecified
2.7
19.3
134
608
M01AH05
ATC
etoricoxib; oral
2.5
19.0
286
1859
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
19.0
180
948
M54.1
ICD-10 Finland
Radiculopathy
19.8
18.9
28
15
N02AJ06
ATC
codeine and paracetamol; systemic
2.5
18.9
207
1166
R51.80
ICD-10 Finland
Headache
3.1
18.8
95
363
N02BF02
ATC
pregabalin; oral
5.2
18.6
40
83
N06CA01
ATC
amitriptyline and psycholeptics; systemic
4.2
18.4
52
135
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
6.5
18.4
31
51
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
187.2
17.6
18
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.7
17.6
124
564
Z50.1
ICD-10 Finland
Other physical therapy
5.4
17.5
36
72
A02BC02
ATC
pantoprazole; systemic
2.4
17.0
297
2021
N06AX16
ATC
venlafaxine; oral
3.0
16.6
86
331
R06.0
ICD-10 Finland
Dyspnoea
2.5
16.4
129
617
UJF32
NOMESCO Finland
Coloscopy
2.6
16.1
116
531
A02BC01
ATC
omeprazole; systemic
2.6
16.0
120
559
R53
ICD-10 Finland
Malaise and fatigue
2.5
15.7
129
628
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
15.7
105
463
M50.3
ICD-10 Finland
Other cervical disc degeneration
39.6
15.5
19
5
SPAT1301
SPAT
No procedures
2.4
15.5
146
755
N05CF01
ATC
zopiclone; oral
2.4
15.4
149
779
L28
ICPC
Limited function/disability (L)
2.9
15.2
82
322
N05AH04
ATC
quetiapine; oral
2.6
15.1
103
457
G44.2
ICD-10 Finland
Tension-type headache
3.1
15.1
71
258
R03AC02
ATC
salbutamol; inhalant
2.2
15.1
261
1732
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.1
15.1
44
117
SPAT1097
SPAT
Recording of ECG
3.1
15.0
71
259
N02BE01
ATC
paracetamol; systemic, rectal
3.6
15.0
400
3228
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
58.8
14.9
17
*
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
13.2
14.6
25
20
M01AX17
ATC
nimesulide; oral
2.6
14.4
99
441
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
23.2
14.3
20
9
M03BC51
ATC
orphenadrine, combinations; systemic
2.4
14.2
121
595
M01AE02
ATC
naproxen; oral, rectal
2.2
14.1
259
1743
M01AB05
ATC
diclofenac; systemic, rectal
2.2
14.1
288
2021
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.9
14.0
72
275
A02BC03
ATC
lansoprazole; oral
2.4
14.0
124
621
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.5
13.9
51
159
J01AA02
ATC
doxycycline; systemic
2.4
13.9
333
2488
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.4
13.7
112
540
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
+∞
13.6
13
*
WX720
NOMESCO Finland
Own respiration
4.8
13.5
31
68
R02
ICPC
Shortness of breath/dyspnoea
3.0
13.5
67
251
M01AC06
ATC
meloxicam; systemic, rectal
2.2
13.4
149
818
WX704
NOMESCO Finland
Intubation
3.6
13.4
46
137
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
41.4
13.2
16
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
17.4
13.1
20
12
A07EC01
ATC
sulfasalazine; oral, rectal
4.0
13.0
38
101
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.0
12.9
63
234
R42
ICD-10 Finland
Dizziness and giddiness
2.5
12.7
99
465
H02AB06
ATC
prednisolone; systemic
2.1
12.7
203
1280
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
72.0
12.7
14
*
M41.9
ICD-10 Finland
Scoliosis, unspecified
33.1
12.7
16
5
M47.81
ICD-10 Finland
Other spondylosis, occipito-atlanto-axial region
+∞
12.6
12
*
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
12.6
12
*
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
+∞
12.6
12
*
C07AA05
ATC
propranolol; systemic
2.4
12.5
107
525
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
5.6
12.4
24
45
M25.5
ICD-10 Finland
Pain in joint
2.2
12.4
148
833
L01
ICPC
Neck symptom/complaint
2.6
12.0
78
336
M54.8
ICD-10 Finland
Other dorsalgia
6.1
11.9
21
36
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.3
11.9
106
528
N02AA05
ATC
oxycodone; systemic
2.6
11.7
74
314
M45
ICD-10 Finland
Ankylosing spondylitis
66.8
11.7
13
*
M43.0
ICD-10 Finland
Spondylolysis
66.8
11.7
13
*
K30
ICD-10 Finland
Functional dyspepsia
2.9
11.7
58
217
N03AE01
ATC
clonazepam; systemic
4.1
11.6
33
86
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
11.6
116
606
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
11.5
73
310
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
11.5
11
*
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
123.1
11.5
12
*
SPAT1263
SPAT
Sampling
2.0
11.4
184
1152
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.3
11.4
105
530
M79.1
ICD-10 Finland
Myalgia
2.5
11.3
78
345
N06AB04
ATC
citalopram; systemic
2.3
11.3
96
468
M54
ICD-10 Finland
Dorsalgia
2.8
11.3
60
233
N04BC05
ATC
pramipexole; oral
3.6
11.1
37
108
Z3226
NOMESCO Finland
Physiotherapist
2.5
11.1
81
368
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
44.5
11.0
13
*
L04
ICPC
Chest symptom/complaint
3.3
10.7
41
131
R01AD08
ATC
fluticasone; nasal
2.1
10.6
133
755
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
4.8
10.6
24
52
C07AB07
ATC
bisoprolol; oral
2.0
10.6
188
1210
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
+∞
10.5
10
*
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
8.5
10.4
22
27
A02BA02
ATC
ranitidine; systemic
2.4
10.4
79
365
WX725
NOMESCO Finland
Noninvasive ventilation
4.0
10.4
30
79
WX110
NOMESCO Finland
Infiltration anesthesia
2.1
10.3
327
2554
J31.0
ICD-10 Finland
Chronic rhinitis
2.9
10.0
49
181
A07AA02
ATC
nystatin; oral
4.3
10.0
26
63
N06AX03
ATC
mianserin; oral
4.4
10.0
25
59
M79.0
ICD-10 Finland
Rheumatism, unspecified
9.1
9.9
20
23
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.3
9.8
80
381
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
9.7
71
322
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
9.7
193
1280
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.5
9.7
65
283
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
9.5
67
298
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.0
9.5
130
759
M41.2
ICD-10 Finland
Other idiopathic scoliosis
+∞
9.4
9
*
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
+∞
9.4
9
*
7245A
ICD-9 Finland
Other and unspecified disorders of back, Backache, unspecified
+∞
9.4
9
*
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
+∞
9.4
9
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
3.4
9.4
35
110
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.5
9.4
64
281
J01DB01
ATC
cefalexin; oral
2.2
9.4
366
3024
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.1
9.4
115
645
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.0
9.3
133
787
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.8
9.3
49
189
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.9
9.3
171
1103
SPAT1240
SPAT
Therapeutic discussion
2.5
9.2
60
257
G43.9
ICD-10 Finland
Migraine, unspecified
3.4
9.2
34
106
A02BA04
ATC
nizatidine; systemic
3.7
9.2
30
86
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.7
9.2
30
86
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
9.2
85
426
N05BA04
ATC
oxazepam; oral
2.0
9.1
114
644
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.8
9.0
47
180
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.8
9.0
244
1773
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
9.0
206
1421
M77.1
ICD-10 Finland
Lateral epicondylitis
2.9
8.9
43
158
M02AA10
ATC
ketoprofen; topical
2.4
8.8
64
289
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.5
8.8
31
94
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.2
8.8
35
115
R01AD09
ATC
mometasone; nasal
1.8
8.8
198
1356
L84
ICPC
Back syndrome without radiat pain
3.9
8.7
26
70
R13
ICD-10 Finland
Dysphagia
3.3
8.7
33
105
R55
ICD-10 Finland
Syncope and collapse
2.7
8.7
49
196
J01FA10
ATC
azithromycin; systemic
1.8
8.6
257
1910
WX402
NOMESCO Finland
General anaesthesia
2.1
8.6
101
555
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.8
8.6
46
179
SPAT1153
SPAT
Removal of sutures
2.0
8.5
121
712
WX702
NOMESCO Finland
Supraglottic ventilation device
3.2
8.5
34
112
UJD02
NOMESCO Finland
Gastroscopy
3.9
8.5
25
67
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.8
8.4
44
169
M01AH03
ATC
valdecoxib; oral
3.7
8.4
27
77
J01DA01
ATC
[U] cefalexin
1.8
8.4
259
1941
M40.1
ICD-10 Finland
Other secondary kyphosis
+∞
8.4
8
*
N02AJ13
ATC
tramadol and paracetamol; systemic
9.7
8.3
16
17
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
9.7
8.3
16
17
UKC02
NOMESCO Finland
Cystoscopy
2.4
8.3
59
264
A03FA01
ATC
metoclopramide; systemic, rectal
2.1
8.3
91
488
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
8.2
234
1708
N06AB05
ATC
paroxetine; oral
3.2
8.2
33
109
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.6
8.2
49
202
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
12.0
8.1
14
12
R52.9
ICD-10 Finland
Pain, unspecified
2.6
8.1
48
197
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.3
8.0
31
100
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.1
8.0
80
414
C03CA01
ATC
furosemide; systemic
2.0
7.9
101
571
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
7.9
77
394
Z3231
NOMESCO Finland
Registered nurse
1.9
7.8
118
706
A28
ICPC
Limited function/disability NOS
2.3
7.8
66
318
SPAT1284
SPAT
Extensive health certificate
6.1
7.8
20
34
N05CF02
ATC
zolpidem; oral
2.2
7.7
72
361
P01
ICPC
Feeling anxious/nervous/tense
2.2
7.7
71
354
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
7.7
59
272
N05AF03
ATC
chlorprothixene; systemic
4.6
7.7
18
40
N05BA01
ATC
diazepam; systemic, rectal
2.4
7.7
58
266
M01AB08
ATC
etodolac; oral
3.1
7.7
32
108
R1250
NOMESCO Finland
Evaluation of functional capability
6.9
7.7
18
27
R03BB04
ATC
tiotropium bromide; inhalant
2.9
7.7
37
136
R01AD12
ATC
fluticasone furoate; nasal
1.8
7.6
141
900
J45
ICD-10 Finland
Asthma
2.6
7.6
45
184
M70.6
ICD-10 Finland
Trochanteric bursitis
2.6
7.6
45
184
A06AD11
ATC
lactulose; oral
2.4
7.5
55
249
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.4
7.5
27
83
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.5
7.5
26
78
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
4.5
7.5
18
41
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.6
7.5
46
192
M13.9
ICD-10 Finland
Arthritis, unspecified
3.0
7.4
34
121
G55.1*M51.9
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders (M50-M51+)
81.4
7.4
8
*
ABD32
NOMESCO Finland
Implantation of temporary spinal stimulation device
81.4
7.4
8
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
7.4
53
237
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
7.4
116
701
N05CD07
ATC
temazepam; oral
2.5
7.4
47
199
N06AB10
ATC
escitalopram; oral
2.0
7.4
99
568
SPAT1310
SPAT
Counselling related to known health issue
1.8
7.4
131
824
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.5
7.4
46
193
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
7.4
96
546
R01BA52
ATC
pseudoephedrine, combinations; oral
1.9
7.4
113
679
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
7.3
321
2616
G54.0
ICD-10 Finland
Brachial plexus disorders
9.6
7.3
14
15
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.7
7.3
40
157
NAG65
NOMESCO Finland
Anterior and posterior fusion of lumbar spine
+∞
7.3
7
*
7225A
ICD-9 Finland
Intervertebral disk disorders, Degeneration of thoracic or lumbar intervertebral disk[DEGENERATIO DISCI INTERVERTEBRALIS THORAC SEU LUMB]
+∞
7.3
7
*
M96.1
ICD-10 Finland
Postlaminectomy syndrome, not elsewhere classified
+∞
7.3
7
*
NA2AD
NOMESCO Finland
Thoracic spine CT examination
+∞
7.3
7
*
N05BA12
ATC
alprazolam; oral
2.5
7.3
49
213
205
Kela drug reimbursment
Chronic hypertension
2.0
7.3
94
532
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
7.3
79
420
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.7
7.2
23
65
J01MA02
ATC
ciprofloxacin; systemic
1.8
7.2
147
963
R4110, ,
SPAT
2.3
7.2
56
260
K02.1
ICD-10 Finland
Caries of dentine
1.7
7.2
268
2081
UJF30
NOMESCO Finland
Ileoscopy through colon
2.5
7.1
44
184
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.3
7.1
18
43
SAA02
NOMESCO Finland
Basic examination of mouth
1.8
7.0
299
2403
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
7.0
134
862
N05AB03
ATC
perphenazine; systemic, rectal
3.6
6.9
23
67
F34.1
ICD-10 Finland
Dysthymia
3.5
6.9
24
72
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
6.9
86
480
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
6.9
40
162
D07AC01
ATC
betamethasone; topical
1.8
6.9
148
983
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
6.9
76
407
P29
ICPC
Psychological sympt/compl other
2.5
6.9
46
200
M35.7
ICD-10 Finland
Hypermobility syndrome
11.2
6.8
12
11
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.6
6.8
40
163
C01DA14
ATC
isosorbide mononitrate; oral
2.4
6.8
49
220
SFA20
NOMESCO Finland
Two-surface restoration
1.7
6.8
259
2008
G04BD08
ATC
solifenacin; oral
3.1
6.8
28
94
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
40.7
6.8
8
*
R52.1
ICD-10 Finland
Chronic intractable pain
40.7
6.8
8
*
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
17.0
6.8
10
6
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.4
6.7
49
221
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.3
6.7
55
261
A11
ICPC
Chest pain NOS
2.6
6.7
40
164
P03
ICPC
Feeling depressed
2.3
6.7
52
241
R20.2
ICD-10 Finland
Paraesthesia of skin
2.9
6.7
32
117
K04.1
ICD-10 Finland
Necrosis of pulp
2.2
6.7
57
276
A01AB09
ATC
miconazole; local oral
2.7
6.6
37
147
C10AA03
ATC
pravastatin; oral
2.9
6.6
31
112
H01
ICPC
Ear pain/earache
2.2
6.6
58
284
ZXA00
NOMESCO Finland
Right side
1.9
6.6
98
581
R03AC03
ATC
terbutaline; inhalant
2.1
6.6
62
312
SFA10
NOMESCO Finland
One-surface restoration
1.7
6.6
243
1863
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
6.6
55
264
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.0
6.6
79
436
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.6
6.5
21
60
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
6.5
48
218
S97
ICPC
Chronic ulcer skin
2.9
6.5
30
108
R03DC03
ATC
montelukast; oral
2.0
6.4
70
372
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
6.4
152
1033
M53.2
ICD-10 Finland
Spinal instabilities
70.8
6.4
7
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.0
6.4
28
97
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.3
6.4
51
239
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.4
6.4
46
207
N03AF01
ATC
carbamazepine; oral, rectal
3.5
6.4
22
66
M02AA07
ATC
piroxicam; topical
1.8
6.3
126
815
A46
ICD-10 Finland
Erysipelas
2.1
6.3
62
317
J01FA09
ATC
clarithromycin; systemic
1.8
6.3
126
816
H04.10
ICD-10 Finland
Dry eye syndrome
2.3
6.3
48
221
C07AB02
ATC
metoprolol; systemic
2.0
6.3
68
361
SPAT1254
SPAT
Administration of medicine
2.1
6.3
62
318
G56.2
ICD-10 Finland
Lesion of ulnar nerve
3.8
6.3
19
52
M40.0
ICD-10 Finland
Postural kyphosis
+∞
6.3
6
*
M42
ICD-10 Finland
Spinal osteochondrosis
+∞
6.3
6
*
G99.2*M50.0
ICD-10 Finland
Cervical disc disorder with myelopathy
+∞
6.3
6
*
72870
ICD-8 Finland
Vertebrogenic pain syndrome, Lumbalgia
+∞
6.3
6
*
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
+∞
6.3
6
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.6
6.2
20
57
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
4.1
6.2
17
43
R51.81
ICD-10 Finland
Facial pain NOS
6.4
6.2
15
24
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
6.2
172
1218
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.5
6.2
40
171
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.1
6.2
25
83
D01
ICPC
Abdominal pain/cramps general
2.2
6.2
53
257
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
6.2
53
257
N03AX09
ATC
lamotrigine; oral
3.0
6.2
27
94
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.2
6.1
24
78
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
6.1
177
1266
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.9
6.1
28
100
N30.9
ICD-10 Finland
Cystitis, unspecified
3.0
6.1
26
89
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.3
6.1
23
73
J01CA04
ATC
amoxicillin; systemic
1.9
6.1
356
3058
E66.01
ICD-10 Finland
Obesity due to excess calories
2.3
6.1
46
211
WZC00, ,
SPAT
2.1
6.1
63
329
M77.4
ICD-10 Finland
Metatarsalgia
2.8
6.1
30
112
P76
ICPC
Depressive disorder
2.6
6.0
36
148
R07.3
ICD-10 Finland
Other chest pain
2.3
6.0
44
199
J01MA12
ATC
levofloxacin; systemic
2.0
6.0
70
381
R01AD58
ATC
fluticasone, combinations; nasal
1.8
6.0
113
718
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
6.0
39
167
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
126
595
2.56
16.42
1.5
1.3
19.34
29.79
iu/ml
0.93
36
187
115
532
2.57
15.55
1.4
1.3
2.80
8.84
u/ml
1.78
49
198
229
1448
2.21
14.85
14.1
12.1
1.17
1.22
inr
0.89
191
1208
175
993
2.26
14.84
2.9
2.6
55.17
70.26
u/l
1.11
163
928
340
2534
2.49
14.73
6.1
3.7
10.19
10.50
mm/h
0.18
329
2350
355
2702
2.61
14.64
4.9
3.9
14.97
14.76
pmol/l
0.80
336
2470
167
949
2.22
13.93
2.7
2.1
208.43
237.76
u/l
0.30
160
905
197
1200
2.16
13.75
4.0
3.4
31.27
37.85
ng/l
0.38
126
796
280
1954
2.19
13.72
5.8
5.3
6.55
6.72
mmol/l
0.67
267
1838
97
445
2.51
13.15
1.9
1.6
1048.64
1151.89
nmol/l
0.59
77
340
341
2605
2.36
12.97
9.1
7.8
76.83
78.83
u/l
0.49
327
2465
145
807
2.19
12.50
2.6
2.1
2.58
2.84
mg/l
0.91
127
703
212
1378
2.04
11.98
5.8
5.2
36.22
36.34
g/l
0.12
200
1302
118
618
2.24
11.73
2.0
1.7
399.49
29401172.25
pmol/l
0.69
100
534
292
2145
2.07
11.55
6.2
3.8
88.86
1172.73
e6/l
—
7
33
395
3292
2.92
11.40
6.3
4.6
1.75
1.85
mu/l
1.15
384
3055
232
1590
1.97
10.96
8.5
7.4
1.22
1.21
mmol/l
1.38
214
1381
125
687
2.14
10.92
3.1
2.7
5.24
5.48
e6/l
0.07
115
628
414
3584
3.53
10.29
22.3
12.8
19.08
24.63
mg/l
4.59
361
2870
207
1388
1.93
10.21
2.4
1.9
95.64
96.58
pmol/l
0.09
113
735
247
1760
1.92
10.08
6.2
6.9
10.85
11.81
umol/l
0.62
240
1685
144
864
1.99
9.76
3.2
3.5
1949.95
1299.26
ng/l
0.46
128
724
100
526
2.17
9.65
2.5
2.4
13.45
13.88
umol/l
0.24
92
489
129
750
2.02
9.53
1.7
1.6
0.94
1.11
mg/l
0.45
103
561
271
2015
1.89
9.45
11.6
10.5
4.21
4.01
e9/l
0.69
246
1756
218
1514
1.87
9.41
3.4
2.7
—
—
estimate
—
0
0
247
1795
1.85
9.13
4.4
3.3
0.00
0.90
estimate
0.52
47
341
233
1663
1.85
9.13
3.6
2.8
103.45
119.34
ug/l
0.90
222
1570
246
1787
1.85
9.09
4.4
3.2
0.00
13.37
estimate
1.07
51
379
141
869
1.92
8.67
3.3
2.6
346.59
352.33
umol/l
0.29
128
790
243
1775
1.82
8.66
4.5
3.2
0.00
0.00
estimate
-0.00
48
372
203
1410
1.81
8.50
6.7
6.9
1.21
1.21
mmol/l
0.01
197
1307
185
1253
1.82
8.39
4.5
3.5
34.09
32.83
u/l
0.15
171
1188
143
896
1.88
8.31
3.4
3.1
0.51
0.37
e6/l
0.21
115
626
83
432
2.13
8.14
4.9
6.1
1.02
1.04
mmol/l
0.30
77
404
107
618
1.97
7.89
5.1
3.3
769.83
653.78
ng/l
0.07
77
454
65
311
2.28
7.83
2.8
3.4
2.55
1.68
mmol/l
1.26
55
263
408
3603
2.77
7.81
24.3
15.2
139.64
139.72
mmol/l
0.27
403
3520
24
67
3.73
7.68
1.6
1.2
—
—
—
0
0
91
501
2.03
7.66
2.5
1.9
—
—
—
0
0
408
3611
2.74
7.63
24.7
15.3
3.95
3.96
mmol/l
0.42
403
3518
24
68
3.67
7.52
1.5
1.5
—
—
—
0
0
73
373
2.15
7.48
2.5
1.7
—
—
—
0
0
124
765
1.86
7.44
4.7
3.2
1.02
1.02
kg/l
0.04
91
497
27
84
3.36
7.37
1.7
1.6
—
—
—
0
0
387
3360
2.24
7.33
6.9
5.6
38.73
38.80
mmol/mol
0.05
371
3190
89
499
1.98
7.09
2.4
2.4
2.41
2.35
g/l
0.43
82
465
209
1520
1.71
7.06
3.1
2.3
73.21
75.07
nmol/l
0.44
203
1397
23
68
3.51
6.79
1.7
1.2
22725.89
23135.72
e6/l
0.01
18
46
159
1089
1.72
6.58
2.7
3.5
2.36
2.35
mmol/l
0.01
142
1004
54
258
2.25
6.51
1.6
1.4
—
—
—
0
0
424
3878
3.42
6.49
14.0
10.3
28.86
28.62
u/l
0.10
419
3767
321
2657
1.76
6.48
4.0
3.1
48.16
47.23
u/l
0.06
299
2529
92
539
1.89
6.40
3.0
2.7
1.19
0.91
e6/l
0.35
55
266
81
455
1.96
6.38
2.5
2.4
22.23
23.49
%
0.36
71
429
132
871
1.74
6.18
1.8
1.6
19.92
19.66
nmol/l
0.07
116
746
44
197
2.37
6.16
3.4
3.5
4.59
4.55
pmol/l
0.09
37
175
49
232
2.25
6.04
1.5
2.8
66.86
66.89
g/l
0.01
42
220
67
361
2.01
5.93
2.6
1.8
—
—
—
0
0
50
242
2.20
5.84
1.8
1.5
—
—
—
0
0
24
82
3.04
5.66
1.2
1.1
0.24
4.42
u/ml
1.49
17
41
362
3149
1.83
5.64
25.4
16.7
13.55
13.46
%
0.65
357
3119
20
63
3.28
5.38
1.1
1.0
19.39
3.59
u/ml
0.38
13
27
21
70
3.10
5.17
1.4
1.6
—
—
—
0
0
20
65
3.18
5.13
1.1
1.1
2.14
1.45
u/ml
0.18
14
31
63
352
1.92
5.01
2.8
5.4
231.21
239.68
u/l
0.26
56
342
181
1353
1.57
4.98
4.4
3.1
12.82
0.03
estimate
0.49
39
313
384
3444
1.89
4.86
5.7
4.3
5.92
5.91
mmol/l
0.05
370
3179
163
1198
1.57
4.79
3.5
3.6
7.84
8.32
mmol/l
0.61
152
1035
87
545
1.74
4.79
1.9
2.0
1.60
1.44
%
1.22
71
502
23
85
2.80
4.75
1.5
1.2
—
—
—
0
0
122
843
1.62
4.62
1.4
1.3
0.73
2.10
u/ml
1.44
38
236
37
176
2.20
4.53
2.9
3.3
1.14
2.25
mmol/l
1.06
28
130
32
143
2.33
4.53
1.9
2.3
18.70
7.16
iu/ml
—
7
33
431
4065
3.66
4.53
32.0
19.8
254.93
248.41
e9/l
1.32
425
3990
431
4068
3.62
4.46
31.9
19.7
4.58
4.61
e12/l
0.56
425
3984
400
3667
1.98
4.27
6.0
5.1
2.75
2.77
mmol/l
0.24
387
3446
20
73
2.82
4.24
1.2
1.1
1.33
2.67
u/ml
0.49
14
37
380
3431
1.78
4.24
4.5
3.8
1.38
1.30
mmol/l
1.09
361
3213
25
103
2.51
4.21
1.7
1.8
—
—
—
0
0
9
13
7.04
4.18
1.2
2.2
—
—
—
0
0
396
3624
1.91
4.17
5.5
4.5
4.68
4.66
mmol/l
0.16
383
3415
63
374
1.80
4.15
7.6
10.4
1.26
0.83
mmol/l
0.54
52
321
74
461
1.73
4.13
5.3
9.1
104.51
104.67
mmol/l
0.11
74
461
41
211
2.04
4.12
2.3
2.8
132.32
132.94
g/l
0.06
41
205
141
1036
1.53
4.02
3.6
2.8
0.69
0.09
estimate
0.41
36
302
145
1074
1.52
3.98
4.4
4.3
9.10
10.29
mg/mmol
0.13
98
694
21
82
2.64
3.94
1.7
3.4
9.34
8.34
kpa
1.55
21
82
127
916
1.54
3.93
4.4
3.4
0.00
0.02
estimate
0.96
46
351
26
113
2.38
3.93
2.0
3.0
24.05
25.38
mmol/l
1.01
26
113
17
60
2.91
3.83
1.6
1.4
—
—
—
0
0
40
210
2.00
3.82
1.2
1.2
—
53.93
—
0
17
393
3612
1.81
3.73
5.3
4.5
1.37
1.42
mmol/l
1.89
380
3395
40
213
1.97
3.68
1.2
1.3
285.41
133.26
u/ml
0.87
15
83
26
117
2.30
3.65
1.5
1.3
—
—
—
0
0
79
519
1.64
3.61
3.3
2.9
2.18
2.37
e6/l
0.07
42
246
111
794
1.53
3.53
2.1
1.5
—
—
—
0
0
8
13
6.24
3.51
2.3
2.2
38.75
71.74
ug/l
—
8
13
22
96
2.36
3.32
1.2
1.3
—
—
—
0
0
65
415
1.66
3.32
1.9
2.6
8.31
8.98
umol/l
0.08
56
367
30
151
2.06
3.23
1.6
1.3
—
—
—
0
0
16
61
2.68
3.17
1.6
1.5
—
—
—
0
0
22
99
2.29
3.11
1.6
2.5
0.51
1.05
g/l
0.44
17
89
6
8
7.58
3.06
1.3
1.0
—
—
—
0
0
21
94
2.30
3.01
2.6
4.1
1.17
2.25
index
0.52
12
57
14
51
2.80
3.01
1.3
1.5
—
—
—
0
0
109
801
1.48
3.01
2.8
2.3
—
—
—
0
0
11
32
3.50
2.92
1.5
2.0
—
—
—
0
0
148
1167
1.40
2.77
4.8
4.3
1.55
2.18
ug/l
1.25
138
1061
29
154
1.95
2.73
2.4
2.5
8071.64
6304.24
u/l
0.08
16
69
11
35
3.20
2.66
1.0
1.2
—
—
—
0
0
25
127
2.03
2.66
1.6
1.6
—
—
—
0
0
18
80
2.30
2.64
2.0
2.0
1.44
4.74
iu/l
—
6
34
376
3484
1.54
2.63
17.6
12.7
87.78
86.54
ml/min/173m2
0.50
353
3172
10
30
3.39
2.62
1.4
1.1
—
—
—
0
0
32
179
1.85
2.59
1.8
2.6
0.60
0.60
%
0.01
32
179
5
7
7.21
2.55
1.4
1.0
—
—
—
0
0
6
11
5.51
2.55
2.0
2.8
—
—
—
0
0
25
130
1.98
2.51
1.5
2.8
1.24
1.39
g/l
0.43
20
118
11
37
3.02
2.50
1.2
2.4
1.19
1.19
mmol/l
0.02
11
37
11
37
3.02
2.50
1.2
2.4
4.23
4.04
mmol/l
0.64
11
37
11
37
3.02
2.50
1.2
2.4
105.91
105.14
mmol/l
0.27
11
37
21
106
2.03
2.29
3.4
2.6
—
—
—
0
0
180
1507
1.33
2.21
2.1
1.9
1.63
1.41
mmol/l
1.40
159
1296
284
2537
1.34
2.21
3.5
3.2
—
—
—
0
0
20
101
2.03
2.19
1.9
1.6
—
—
—
0
0
10
36
2.82
2.15
1.0
1.2
—
—
—
0
0
16
75
2.18
2.11
1.6
1.3
303.33
283.80
ug/g
—
9
42
79
584
1.43
2.09
2.8
3.1
2.47
2.44
mmol/l
0.72
67
532
6
15
4.04
2.04
1.8
1.5
87.00
64.83
ng/l
—
6
15
8
27
3.00
1.94
1.6
1.3
—
—
—
0
0
6
16
3.79
1.94
2.0
1.3
—
—
—
0
0
6
16
3.79
1.94
2.0
1.3
—
—
—
0
0
18
92
2.00
1.93
2.2
3.3
10.93
13.09
mg/l
0.70
18
86
9
34
2.68
1.87
1.0
1.1
—
—
—
0
0
8
28
2.89
1.87
1.1
1.4
—
—
—
0
0
7
23
3.08
1.80
1.0
1.1
—
—
—
0
0
7
24
2.95
1.73
2.3
1.3
66.57
83.13
umol/l
—
7
24
15
76
2.01
1.66
1.5
2.2
—
—
—
0
0
5
131
0.37
1.65
1.8
1.6
59.82
51.95
ug/l
—
5
104
8
171
0.46
1.62
2.0
1.9
—
—
—
0
0
5
14
3.60
1.62
1.0
1.4
—
—
—
0
0
25
152
1.68
1.60
1.6
1.4
—
—
—
0
0
10
43
2.36
1.59
1.3
1.2
—
—
—
0
0
20
114
1.79
1.59
1.6
1.6
0.07
0.13
iu/ml
—
5
18
6
20
3.03
1.58
1.0
1.1
—
—
—
0
0
6
20
3.03
1.58
2.3
1.5
—
—
—
0
0
12
57
2.14
1.56
1.8
2.0
4.91
5.00
mmol/24h
0.03
12
50
23
139
1.69
1.51
1.1
1.4
195.11
273.31
miu/ml
—
9
65
12
59
2.06
1.45
5.6
2.9
5.28
4.99
kpa
0.89
12
59
9
40
2.28
1.41
1.0
1.4
—
—
—
0
0
9
40
2.28
1.41
1.0
1.4
—
—
—
0
0
9
40
2.28
1.41
1.0
1.4
—
—
—
0
0
16
89
1.83
1.39
1.6
2.6
1.04
2.95
ratio
—
9
51
6
24
2.52
1.31
1.3
1.0
—
—
—
0
0
6
24
2.52
1.31
1.3
1.0
—
—
—
0
0
109
910
1.26
1.29
4.6
3.7
19.82
21.25
%
0.56
43
372
30
203
1.51
1.28
1.1
1.0
—
—
—
0
0
16
93
1.75
1.23
1.3
1.6
—
—
—
0
0
8
37
2.18
1.22
1.0
1.5
—
—
—
0
0
8
38
2.13
1.19
1.0
1.4
—
—
—
0
0
8
38
2.13
1.19
1.0
1.4
—
—
—
0
0
7
30
2.35
1.13
1.0
1.2
100.86
105.90
pmol/l
—
7
30
18
112
1.63
1.10
2.3
2.1
—
—
—
0
0
73
593
1.28
1.08
2.3
2.2
—
—
—
0
0
5
22
2.29
1.03
1.0
1.1
—
—
—
0
0
15
91
1.67
1.01
1.1
1.1
—
—
—
0
0
15
91
1.67
1.01
1.1
1.1
—
—
—
0
0
0
29
0.00
0.98
0.0
1.3
—
—
—
0
0
10
54
1.87
0.97
1.1
1.2
—
—
—
0
0
10
54
1.87
0.97
1.1
1.2
—
—
—
0
0
13
77
1.71
0.96
1.4
1.6
56.12
48.94
ug/l
0.39
13
77
67
551
1.25
0.91
2.3
2.0
—
—
—
0
0
40
309
1.32
0.88
7.0
6.3
—
—
—
0
0
11
64
1.74
0.87
1.4
2.0
—
—
—
0
0
52
418
1.28
0.86
2.7
2.4
14.23
13.97
nmol/l
0.10
46
395
41
319
1.31
0.86
2.1
2.2
29.20
181.23
u/l
0.52
35
275
26
188
1.41
0.85
2.3
1.5
—
—
—
0
0
40
314
1.30
0.80
4.0
3.0
—
—
—
0
0
24
174
1.40
0.78
1.3
1.3
—
—
—
0
0
9
54
1.68
0.75
1.0
1.1
—
—
—
0
0
7
40
1.76
0.71
1.0
2.0
—
—
—
0
0
5
27
1.86
0.68
1.2
1.4
—
—
—
0
0
8
50
1.61
0.61
1.7
1.7
—
—
—
0
0
17
122
1.41
0.61
1.8
1.6
12.18
5.72
u/ml
—
6
31
15
105
1.44
0.61
2.2
1.9
—
—
—
0
0
38
309
1.25
0.60
2.7
5.5
4.41
21.01
ug/l
0.65
30
257
31
246
1.28
0.60
1.9
2.8
71.83
68.44
ml/min/173m2
0.15
12
112
6
35
1.72
0.58
5.5
2.4
—
—
—
0
0
6
36
1.68
0.57
1.0
2.1
—
—
—
0
0
6
39
1.55
0.53
1.3
1.1
—
—
—
0
0
32
388
0.81
0.50
1.8
1.7
4.00
3.55
mmol/l
1.64
25
276
44
516
0.84
0.50
1.8
1.9
3.95
3.63
ratio
0.83
37
400
12
84
1.44
0.49
1.5
1.4
—
—
—
0
0
7
51
1.38
0.44
1.6
2.7
27.29
19.13
u/ml
—
7
51
5
33
1.52
0.41
4.2
4.7
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
95.67
—
0
12
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
17
0.00
0.40
0.0
1.1
—
113.59
—
0
17
8
60
1.34
0.40
1.1
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
104.92
—
0
13
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
17
133
1.29
0.39
1.2
1.7
14.48
7.00
u/l
0.73
12
108
11
81
1.37
0.36
1.6
2.1
—
—
—
0
0
13
99
1.32
0.36
1.4
1.7
—
—
—
0
0
10
73
1.38
0.35
1.8
1.6
—
—
—
0
0
7
52
1.35
0.31
1.6
1.7
—
—
—
0
0
7
56
1.25
0.29
1.0
1.1
—
—
—
0
0
12
151
0.79
0.28
1.8
2.3
175.33
58.89
u/ml
0.48
12
144
24
206
1.17
0.27
1.8
1.6
0.13
0.32
mg/l
4.05
11
105
35
312
1.13
0.25
2.8
2.1
—
—
—
0
0
77
718
1.09
0.25
3.3
2.7
0.50
0.76
ug/l
4.12
48
398
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
12
145
0.82
0.21
1.1
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
7
63
1.11
0.17
1.4
3.7
13.86
10.56
pmol/l
—
7
63
5
66
0.75
0.17
1.6
1.2
—
—
—
0
0
8
71
1.13
0.16
5.4
3.7
—
4918.40
—
0
5
44
471
0.93
0.15
1.4
1.6
—
—
—
0
0
11
93
1.19
0.14
1.5
1.8
—
—
—
0
0
7
66
1.06
0.08
1.3
1.1
—
—
—
0
0
28
264
1.06
0.08
2.9
2.0
—
—
—
0
0
9
85
1.06
0.07
1.6
1.6
1.10
0.89
nmol/l
—
9
73
20
187
1.07
0.06
1.0
1.2
0.96
0.93
g/l
0.10
20
187
40
408
0.98
0.01
3.8
4.2
29.07
31.64
%
0.68
28
272
11
115
0.96
0.00
1.1
1.6
—
—
—
0
0
18
184
0.98
0.00
1.0
1.1
1.45
1.51
g/l
0.50
18
184
0
5
0.00
0.00
0.0
1.6
—
5.88
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
0.40
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
2.80
—
0
5
0
5
0.00
0.00
0.0
1.0
—
516.60
—
0
5
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
9.17
—
0
6
0
6
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
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Mortality – FinRegistry
↥Association
Association between endpoint M13_SPINALOSTEOCHON and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SPINALOSTEOCHON | 1.195 [1.02, 1.41] | 0.031 |
| Birth year | 0.994 [0.99, 1.0] | 0.182 |
During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 1341 females with M13_SPINALOSTEOCHON died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SPINALOSTEOCHON | 1.222 [1.01, 1.48] | 0.041 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 212 out of 1938 males with M13_SPINALOSTEOCHON died.
Mortality risk
Mortality risk for people of age
years, who have M13_SPINALOSTEOCHON.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.115% | 0.219% |
| 5 | 0.877% | 1.405% |
| 10 | 1.929% | 3.729% |
| 15 | 3.596% | 6.762% |
| 20 | 6.181% | 11.273% |
Relationships between endpoints
↥Index endpoint: M13_SPINALOSTEOCHON – Spinal osteochondrosis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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