Melanocytic naevi of ear and external auricular canal

CD2_BENIGN_MELANOCYTIC_EAR

cutaneous melanoma: A primary melanoma arising from atypical melanocytes in the skin. Precursor lesions include acquired and congenital melanocytic nevi, and dysplastic nevi. Several histologic variants have been recognized, including superficial spreading melanoma, acral lentiginous melanoma, nodular melanoma, and lentigo maligna melanoma.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D22.2&
  • Hospital discharge: ICD-9 2162A
  • Cause of death: ICD-10 D22.2&
  • Cause of death: ICD-9 2162A

2 out of 7 registries used, show all original rules.

238

4. Check minimum number of events

None

238

5. Include endpoints

None

238

6. Filter based on genotype QC (FinnGen only)

223

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) auriculae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1330 810 508
Only index persons 1251 778 473
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.01
Only index persons 0.02 0.03 0.02
Median age at first event (years)
Whole population 49.38 45.07 56.22
Only index persons 48.91 44.97 55.38

-FinnGen-

Key figures

All Female Male
Number of individuals 223 150 73
Unadjusted period prevalence (%) 0.05 0.05 0.03
Median age at first event (years) 51.90 45.93 64.16

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
226
Matched controls
2260
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D22.2
ICD-10 Finland
Melanocytic naevi of ear and external auricular canal
4503599627370496.0
302.8
218
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
11.8
62.1
77
95
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.4
35.0
60
105
DAB00
NOMESCO Finland
Excision of lesion of auricle
47.9
27.6
33
8
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
6.8
24.2
42
73
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
32.9
16.4
21
7
R23.8
ICD-10 Finland
Other and unspecified skin changes
3.2
14.8
80
329
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
5.3
14.8
32
68
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
4.9
14.4
35
82
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
12.1
11.3
20
18
DAB10
NOMESCO Finland
Partial excision of auricle
45.7
11.0
13
*
S82
ICPC
Naevus/mole
3.0
10.4
57
231
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
10.8
9.7
18
18
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
4.2
9.3
26
68
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
8.2
8.8
19
25
XQ848
NOMESCO Finland
Dermatological photography
9.1
8.5
17
20
2162A
ICD-9 Finland
Benign neoplasm of skin, Ear and external auditory canal[KORVAN IHON BEN KASVAIN,NAEVUS PIGMENTOSUS]
+∞
8.4
8
*
XQ845
NOMESCO Finland
Dermatoscopy
10.6
8.2
15
15
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
3.6
7.7
27
83
L82
ICD-10 Finland
Seborrhoeic keratosis
2.5
7.6
56
262
D22
ICD-10 Finland
Melanocytic naevi
3.7
6.8
22
64
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
10.5
6.6
12
12
TQW99
NOMESCO Finland
Other minor procedure on skin
3.7
6.5
21
61
TDA10
NOMESCO Finland
Needle biopsy of auricle or external auditory canal
27.5
6.3
8
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
3.3
6.1
23
74

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
143
835
2.94
13.71
3.2
2.1
—
—
—
0
0
62
256
2.96
11.00
1.8
1.2
—
—
—
0
0
36
160
2.49
5.33
1.4
1.3
—
—
—
0
0
23
83
2.97
5.05
1.7
1.2
—
—
—
0
0
115
847
1.73
3.97
2.4
2.0
98.28
95.79
pmol/l
0.22
65
439
26
116
2.40
3.81
3.5
3.1
171.46
254.56
ng/l
0.64
26
105
58
363
1.80
3.46
4.2
3.5
72.32
315.91
ng/l
1.55
44
256
109
823
1.63
3.21
4.9
4.4
36.03
36.00
g/l
0.02
99
778
81
572
1.65
3.09
2.9
3.0
0.18
0.42
e6/l
1.59
59
417
121
945
1.60
3.05
5.8
6.6
1.21
1.21
mmol/l
0.17
109
829
51
322
1.75
2.92
2.6
3.0
3.32
2.96
e6/l
0.07
19
153
212
1950
2.41
2.71
16.0
14.8
24.34
22.59
mg/l
0.30
176
1581
36
212
1.83
2.59
1.8
2.7
5.58
6.32
umol/l
0.30
29
184
81
596
1.56
2.53
3.5
3.9
7.39
7.39
ph
0.16
58
419
127
1039
1.51
2.38
6.7
6.3
10.55
10.76
umol/l
0.13
121
989
86
660
1.49
2.15
3.1
3.2
77.67
159.75
e6/l
0.36
65
502
81
617
1.49
2.09
6.9
6.1
—
—
—
0
0
19
98
2.02
2.02
2.0
1.9
—
—
—
0
0
31
189
1.74
2.00
3.6
4.9
2.70
30.63
ug/l
0.68
24
157
168
1487
1.51
1.93
9.3
7.9
76.44
78.17
u/l
0.22
160
1410
106
866
1.42
1.85
5.3
5.8
1.21
1.21
mmol/l
0.55
99
804
70
531
1.46
1.81
2.8
2.1
2.33
2.80
mg/l
0.88
58
466
95
766
1.41
1.76
4.1
4.0
31.56
72.53
e6/l
1.52
69
529
6
19
3.21
1.67
2.2
1.3
—
—
—
0
0
5
14
3.63
1.62
3.4
4.6
548.20
710.86
mg
—
5
14
10
43
2.39
1.61
1.3
1.3
—
—
—
0
0
8
33
2.48
1.55
2.0
1.5
—
—
—
0
0
7
28
2.55
1.46
1.1
1.2
—
—
—
0
0
12
59
2.09
1.46
1.3
1.2
—
—
—
0
0
74
588
1.38
1.45
1.9
1.7
19.01
20.86
nmol/l
0.49
60
501
6
23
2.65
1.37
1.0
1.0
—
—
—
0
0
6
23
2.65
1.37
2.7
1.8
—
—
—
0
0
24
154
1.62
1.32
2.7
4.2
7.36
7.37
ph
0.23
15
108
5
18
2.82
1.29
1.4
1.3
—
—
—
0
0
9
44
2.09
1.28
1.1
1.1
—
—
—
0
0
9
44
2.09
1.28
1.1
1.1
—
—
—
0
0
38
274
1.47
1.26
1.8
1.9
—
—
—
0
0
124
1084
1.32
1.25
3.5
3.8
0.00
0.00
estimate
-0.00
18
237
6
25
2.44
1.25
1.8
2.0
—
—
—
0
0
21
133
1.64
1.22
1.2
1.3
—
—
—
0
0
75
613
1.33
1.21
2.7
2.5
56.33
64.66
u/l
0.46
67
581
6
26
2.34
1.19
1.3
1.4
—
—
—
0
0
190
1778
1.43
1.16
6.6
5.8
37.96
38.56
mmol/mol
0.50
179
1682
18
111
1.68
1.16
1.1
1.1
—
—
—
0
0
81
674
1.31
1.14
6.3
5.5
—
—
—
0
0
64
517
1.33
1.11
3.5
4.0
—
—
—
0
0
5
21
2.41
1.09
1.4
1.0
—
—
—
0
0
36
265
1.43
1.09
1.4
1.3
—
—
—
0
0
124
1098
1.29
1.08
3.6
3.8
0.00
0.00
estimate
-0.00
18
239
7
34
2.09
1.04
1.1
1.1
—
—
—
0
0
124
1102
1.28
1.03
3.6
3.8
0.00
1.35
estimate
0.50
18
224
11
61
1.84
1.00
1.7
2.9
—
—
—
0
0
6
118
0.50
0.97
1.2
1.1
—
—
—
0
0
199
1892
1.43
0.96
5.1
4.8
4.70
4.66
mmol/l
0.26
187
1779
207
1983
1.52
0.96
13.4
13.2
—
—
—
0
0
201
1915
1.45
0.96
5.9
5.4
2.77
2.72
mmol/l
0.30
187
1794
70
584
1.29
0.95
4.1
3.9
3.70
11.39
mg/mmol
2.36
41
369
6
27
2.25
0.94
1.2
1.3
—
—
—
0
0
6
28
2.17
0.92
1.3
1.2
—
—
—
0
0
13
79
1.68
0.90
1.4
1.5
1.42
1.32
mm
—
7
60
30
222
1.41
0.89
1.7
1.6
—
—
—
0
0
16
104
1.58
0.87
2.8
4.4
—
—
—
0
0
13
80
1.66
0.86
1.4
1.5
—
—
—
0
0
130
1178
1.24
0.86
10.2
9.4
4.35
4.08
e9/l
0.66
108
1013
69
582
1.27
0.86
3.7
3.3
27.49
66.96
mg/l
1.87
40
387
73
621
1.26
0.84
3.1
2.7
—
—
—
0
0
24
173
1.43
0.83
1.7
1.4
—
—
—
0
0
11
66
1.70
0.80
1.2
1.3
—
—
—
0
0
210
2028
1.50
0.80
13.4
11.4
22.21
24.41
u/l
2.61
204
1978
13
82
1.62
0.80
1.4
1.6
—
—
—
0
0
17
115
1.52
0.79
2.7
2.1
18746.59
5372.43
u/l
—
9
40
93
819
1.23
0.78
13.3
11.5
1.19
1.20
inr
0.01
76
669
99
878
1.23
0.78
3.4
3.4
6.31
6.18
ph
0.56
59
497
75
647
1.24
0.76
3.5
3.1
7.74
7.86
mmol/l
0.07
61
555
5
24
2.11
0.75
1.8
1.5
—
—
—
0
0
39
311
1.31
0.74
1.5
1.6
1069.89
1138.11
nmol/l
0.22
29
241
55
459
1.26
0.74
6.2
5.9
1.76
3.00
ug/l
0.96
47
399
7
38
1.87
0.74
2.7
3.2
3.07
6.44
umol/l
—
7
27
5
25
2.02
0.73
1.0
1.0
—
—
—
0
0
31
241
1.33
0.71
4.4
5.3
1.05
1.08
mmol/l
0.12
26
219
7
41
1.73
0.70
1.0
1.4
—
—
—
0
0
5
27
1.87
0.69
6.8
3.2
5.60
3.08
nmol/l
—
5
27
23
172
1.38
0.67
1.5
1.6
952.37
933.91
mu/l
0.02
16
148
106
958
1.20
0.67
2.6
2.8
—
—
estimate
—
0
0
146
1362
1.20
0.64
3.3
3.2
38.54
41.15
u/l
0.24
136
1301
35
283
1.28
0.61
3.1
2.5
79.29
118.46
ug/g
0.78
28
232
117
1073
1.19
0.61
3.8
3.1
78.61
96.19
ug/l
0.73
111
1016
196
1887
1.29
0.61
5.1
4.7
1.49
1.51
mmol/l
0.25
182
1766
71
623
1.20
0.60
2.6
3.1
0.00
0.14
estimate
0.52
16
188
7
112
0.61
0.60
2.9
2.8
1.19
1.29
%
—
7
112
7
111
0.62
0.60
2.9
2.8
0.67
0.61
%
—
7
111
165
1564
1.20
0.57
4.4
4.5
14.45
14.65
pmol/l
0.48
151
1436
27
213
1.30
0.57
6.9
7.2
1.44
0.64
mmol/l
0.43
20
180
117
1078
1.18
0.57
6.8
6.0
2.04
1.90
e9/l
0.59
99
955
8
55
1.47
0.56
1.4
1.3
—
—
—
0
0
108
991
1.17
0.54
7.1
5.9
29.91
27.98
%
1.17
101
943
9
61
1.49
0.54
1.2
1.1
—
—
—
0
0
13
91
1.45
0.54
1.3
1.9
—
—
—
0
0
46
392
1.22
0.53
2.9
2.5
2.44
2.44
mmol/l
0.07
40
355
27
216
1.28
0.52
7.0
7.2
7.39
7.42
ph
0.62
16
122
53
460
1.20
0.51
3.6
1.7
1.51
1.25
mg/l
0.15
42
355
122
1136
1.16
0.50
5.4
4.6
6.59
6.43
mmol/l
0.43
111
1056
12
165
0.71
0.48
7.1
4.9
0.20
0.90
%
—
5
54
56
491
1.19
0.48
3.9
3.7
—
0.00
—
0
5
11
153
0.70
0.47
7.5
4.9
0.00
0.59
%
—
5
44
190
1836
1.22
0.47
5.5
4.7
5.86
5.79
mmol/l
0.37
175
1700
73
656
1.17
0.47
2.2
2.3
—
—
—
0
0
106
981
1.15
0.46
6.9
5.8
55.47
57.41
%
1.09
99
933
113
1051
1.15
0.46
6.9
6.0
0.58
0.57
e9/l
0.24
94
899
71
784
0.86
0.44
2.5
2.9
—
—
—
0
0
7
51
1.38
0.44
1.1
1.1
—
—
—
0
0
185
1788
1.19
0.42
4.4
4.0
1.29
1.22
mmol/l
0.83
169
1651
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
287.10
—
0
10
0
16
0.00
0.41
0.0
1.6
—
7.79
—
0
16
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
90
829
1.14
0.41
3.2
3.6
0.00
0.02
estimate
0.74
16
196
13
171
0.75
0.41
4.2
3.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
29
243
1.22
0.40
1.6
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
32
272
1.21
0.39
2.2
1.6
—
—
—
0
0
9
67
1.36
0.38
2.4
2.8
1.22
1.44
mg/l
—
9
56
35
301
1.19
0.38
1.4
1.5
480.00
514.05
titre
—
5
74
12
157
0.75
0.37
7.1
5.1
0.00
0.16
%
—
5
45
11
81
1.38
0.37
2.6
3.2
—
—
—
0
0
5
78
0.63
0.36
1.0
1.1
1.54
1.60
g/l
—
5
78
5
78
0.63
0.36
1.0
1.1
—
0.49
—
0
7
104
974
1.13
0.36
7.2
5.9
8.68
8.66
%
0.02
96
916
112
1054
1.12
0.35
6.9
6.0
0.04
0.04
e9/l
0.01
93
898
6
43
1.41
0.35
4.8
2.8
55.83
62.95
%
—
6
43
116
1095
1.12
0.35
8.3
6.2
0.19
0.18
e9/l
0.27
102
953
15
118
1.29
0.34
3.3
2.1
—
—
—
0
0
46
412
1.15
0.31
2.0
1.7
—
—
—
0
0
103
971
1.11
0.31
7.3
5.9
2.97
2.73
%
0.52
95
911
189
1843
1.16
0.30
5.8
5.4
1.97
1.83
mu/l
0.40
173
1714
11
84
1.33
0.30
1.4
1.3
—
—
—
0
0
19
158
1.22
0.29
2.2
2.0
10.04
10.13
g/l
0.04
19
149
58
531
1.12
0.29
1.2
1.3
0.67
1.70
u/ml
—
7
151
10
76
1.33
0.28
1.2
1.4
—
—
—
0
0
8
63
1.28
0.28
1.4
1.1
—
—
—
0
0
29
253
1.17
0.28
2.4
3.2
3.97
5.06
e9/l
0.47
24
227
13
160
0.80
0.27
1.9
2.7
0.18
0.14
e6/l
0.17
13
154
102
968
1.10
0.26
7.4
5.9
0.68
0.65
%
0.34
92
902
11
87
1.28
0.25
1.2
1.5
252.82
280.02
mu/l
0.38
11
79
6
81
0.73
0.24
2.2
2.4
—
—
—
0
0
6
82
0.72
0.24
1.0
1.2
0.82
0.87
g/l
—
6
82
7
95
0.73
0.22
2.6
3.8
1.02
1.02
ratio
—
7
88
14
116
1.22
0.22
1.1
1.2
—
—
—
0
0
25
282
0.87
0.22
1.2
1.6
—
—
—
0
0
22
192
1.16
0.21
1.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
0.00
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.9
—
47.00
—
0
5
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
1861.70
—
0
10
27
240
1.14
0.21
2.1
1.9
—
—
—
0
0
11
89
1.25
0.21
1.2
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
27
241
1.14
0.20
1.4
1.4
—
—
—
0
0
6
52
1.16
0.19
2.0
1.9
—
—
—
0
0
17
147
1.17
0.18
1.4
1.2
191.24
260.56
u/ml
0.20
17
133
40
433
0.91
0.18
1.3
1.3
22.25
31.67
iu/ml
0.43
11
130
18
205
0.87
0.18
3.6
3.9
7.38
7.38
ph
—
10
119
7
61
1.15
0.17
1.0
1.2
15.17
11.74
u/l
—
7
42
19
215
0.87
0.17
1.3
1.4
—
—
—
0
0
10
82
1.23
0.17
1.2
1.7
—
—
—
0
0
73
694
1.08
0.17
3.9
2.9
2.35
2.35
mmol/l
0.14
62
633
15
172
0.86
0.16
1.6
2.0
5.75
6.16
ph
—
8
107
40
373
1.09
0.15
1.5
1.7
405.74
450.78
pmol/l
0.60
31
323
96
927
1.06
0.14
9.8
10.9
0.00
0.00
e9/l
0.53
76
742
51
485
1.07
0.12
3.6
3.5
1.02
1.02
kg/l
0.78
36
310
5
44
1.14
0.10
1.4
1.5
0.29
0.29
nmol/l
—
5
31
5
46
1.09
0.09
2.6
5.5
—
—
—
0
0
69
713
0.95
0.09
2.8
4.1
19.15
30.52
ng/l
1.20
41
465
11
98
1.13
0.08
1.2
1.4
—
—
—
0
0
8
90
0.88
0.07
1.9
1.8
1.13
1.56
g/l
—
8
81
61
595
1.03
0.05
3.2
3.7
0.00
0.00
estimate
-0.00
19
221
11
119
0.92
0.04
3.1
2.1
13.25
13.06
nmol/l
0.02
11
110
39
401
0.97
0.03
1.3
1.3
6.61
7.69
u/ml
0.07
15
155
47
480
0.97
0.02
4.4
5.0
—
—
—
0
0
18
172
1.05
0.02
1.5
1.8
3.49
3.32
mmol/l
0.28
11
126
19
182
1.05
0.02
9.8
7.8
—
—
—
0
0
50
492
1.02
0.01
1.5
1.4
2.76
2.28
g/l
0.66
27
287
18
173
1.04
0.01
1.3
1.3
105.33
139.69
u/ml
—
6
77
63
623
1.02
0.01
1.8
1.6
—
—
—
0
0
11
108
1.02
0.00
1.2
1.4
—
—
—
0
0
13
132
0.98
0.00
1.8
1.8
—
—
—
0
0
50
499
1.00
0.00
2.5
2.1
—
—
—
0
0
81
811
1.00
0.00
2.0
1.9
1.20
1.33
mmol/l
1.21
69
708
21
207
1.02
0.00
1.9
1.5
—
—
—
0
0
11
106
1.04
0.00
1.2
1.4
—
—
—
0
0
16
165
0.97
0.00
2.1
2.6
78.92
69.63
e9/l
—
10
128
19
195
0.97
0.00
3.6
4.0
3.30
1.51
mmol/l
1.62
14
162
26
262
0.99
0.00
7.8
6.5
104.54
104.55
mmol/l
0.00
26
262
11
105
1.05
0.00
1.2
1.4
—
—
—
0
0
11
105
1.05
0.00
1.2
1.4
—
—
—
0
0
30
298
1.01
0.00
1.7
1.9
—
—
—
0
0
27
272
0.99
0.00
3.4
3.3
0.66
0.79
ug/l
0.39
18
188
0
6
0.00
0.00
0.0
1.0
—
17.87
—
0
6
0
6
0.00
0.00
0.0
1.5
—
9.80
—
0
6
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
99.33
—
0
9
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
37.88
—
0
6
0
9
0.00
0.00
0.0
1.6
—
58.78
—
0
9
0
9
0.00
0.00
0.0
4.9
—
53.22
—
0
9
6
65
0.92
-0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
4.53
—
0
8
0
5
0.00
-0.00
0.0
2.4
—
0.52
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
1.19
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
34.60
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
35.56
—
0
5
0
7
0.00
-0.00
0.0
3.7
—
0.60
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
76.40
—
0
5
6
61
0.98
-0.00
3.8
1.9
147.28
268.45
ug/l
—
6
56
5
55
0.91
-0.00
2.0
1.2
—
121.67
—
0
6

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MELANOCYTIC_EAR and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_EAR 1.145 [0.83, 1.59] 0.414
Birth year 0.995 [0.99, 1.0] 0.269

During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 636 females with CD2_BENIGN_MELANOCYTIC_EAR died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_EAR 1.019 [0.75, 1.38] 0.902
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 390 males with CD2_BENIGN_MELANOCYTIC_EAR died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MELANOCYTIC_EAR.

N-year risk Females Males
1 0.13% 0.203%
5 0.676% 1.113%
10 1.628% 2.915%
15 3.122% 5.533%
20 5.382% 9.116%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MELANOCYTIC_EAR – Melanocytic naevi of ear and external auricular canal

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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