No definition available.
Benign neoplasm: Connective and other soft tissue of thorax
CD2_BENIGN_CONNSOFT_THX
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
182 |
4. Check minimum number of eventsNone |
182 |
5. Include endpointsNone |
182 |
6. Filter based on genotype QC (FinnGen only) |
167 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D21
- Name in latin
- Neoplasma benignum textus connectivi/textus mollis thoracis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Connective and other soft tissue of thorax
based on the number of shared cases.
Similar with more cases:
- Other benign neoplasms of connective and other soft tissue
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1115 | 664 | 446 |
| Only index persons | 1009 | 608 | 401 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 50.52 | 50.31 | 50.70 |
| Only index persons | 50.43 | 50.45 | 50.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 167 | 96 | 71 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | 54.31 | 50.01 | 60.14 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 173
- Matched controls
- 1730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D21.3
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of thorax
+∞
213.8
158
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
11.2
39.8
49
59
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
11.7
11.1
20
19
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
9.2
10.7
22
27
GA1CG
NOMESCO Finland
Extensive MRI of chest
116.8
10.5
11
*
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
116.8
10.5
11
*
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
6.4
6.8
17
29
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
23.6
6.7
9
*
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
15.1
6.5
10
7
2154X
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Thorax[THORAXIN BENIGNI PEHMYTKUDOSKASVAIN,TARK MÄÄRITTELE]
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
108
755
2.15
5.48
8.6
6.9
1.20
1.21
mmol/l
0.37
93
656
120
908
2.05
4.51
4.9
4.9
6.79
6.60
mmol/l
0.42
115
854
21
79
2.89
4.34
1.7
3.5
2.68
2.16
mmol/l
0.39
13
60
45
246
2.12
4.19
1.9
2.0
—
—
—
0
0
96
697
1.85
3.82
6.9
5.8
1.20
1.21
mmol/l
0.74
91
645
91
654
1.83
3.70
2.9
2.6
80.63
76.02
nmol/l
0.75
83
598
15
51
3.13
3.67
1.7
2.7
23.86
25.15
mmol/l
0.58
15
51
8
13
6.39
3.54
1.0
1.5
396.75
241.12
u/l
—
8
13
24
111
2.35
3.31
2.5
3.7
71.73
76.57
ng/l
0.17
19
99
78
552
1.75
3.22
3.3
3.3
—
—
—
0
0
71
493
1.75
3.10
2.3
2.4
60.86
65.81
u/l
0.18
66
460
59
389
1.78
3.08
3.3
2.7
319.14
344.13
umol/l
1.29
49
343
13
47
2.91
2.88
2.3
2.1
—
—
—
0
0
111
883
1.72
2.88
12.9
10.1
3.98
4.15
e9/l
0.33
97
760
68
475
1.71
2.87
3.1
3.4
1455.36
1107.08
ng/l
0.27
63
395
65
450
1.71
2.82
2.9
3.2
0.14
0.45
e6/l
1.72
46
329
6
10
6.17
2.72
1.0
1.3
9.50
12.00
u/l
—
6
10
41
253
1.81
2.62
2.0
1.7
1086.15
1176.34
nmol/l
0.26
29
197
5
7
7.31
2.56
6.2
3.6
4121.80
851.29
u/ml
—
5
7
7
16
4.51
2.50
1.0
1.4
—
—
—
0
0
105
843
1.62
2.46
9.0
6.6
15.36
11.16
umol/l
0.55
99
802
91
709
1.60
2.39
3.1
2.7
—
—
estimate
—
0
0
5
8
6.39
2.38
1.0
1.5
5.66
10.31
u/l
—
5
8
7
18
4.01
2.27
2.0
1.7
—
—
—
0
0
156
1411
2.07
2.20
20.9
15.6
81.52
81.01
ml/min/173m2
0.11
148
1310
43
283
1.69
2.19
5.2
3.6
684.34
261.17
ng/l
0.33
32
209
7
19
3.79
2.17
2.0
1.7
—
—
—
0
0
162
1492
2.35
2.07
24.8
18.4
3.97
3.97
mmol/l
0.06
156
1463
6
15
4.10
2.05
1.2
1.0
—
—
—
0
0
71
537
1.55
2.04
5.6
3.2
2.36
2.36
mmol/l
0.24
66
498
168
1591
2.93
1.99
31.7
24.1
91.02
91.02
fl
0.01
163
1576
168
1591
2.93
1.99
31.9
24.2
250.61
249.48
e9/l
0.08
163
1565
133
1161
1.63
1.96
4.9
4.3
14.64
14.73
pmol/l
0.20
123
1059
16
79
2.13
1.92
1.8
1.9
—
—
—
0
0
6
17
3.62
1.85
2.2
1.8
—
—
—
0
0
130
1135
1.58
1.84
5.2
4.4
12.06
11.64
mm/h
0.13
120
1054
168
1592
2.91
1.84
31.9
24.1
4.45
4.49
e12/l
0.41
163
1556
168
1592
2.91
1.84
32.4
24.5
40.09
40.30
%
0.24
163
1577
161
1493
2.13
1.78
24.8
18.3
139.76
139.72
mmol/l
0.09
156
1470
6
18
3.41
1.76
2.2
1.7
—
—
—
0
0
6
18
3.41
1.76
2.2
1.7
—
—
—
0
0
6
18
3.41
1.76
2.2
1.7
—
—
—
0
0
5
13
3.93
1.72
6.6
5.0
1099.80
685.00
mg
—
5
13
132
1166
1.56
1.68
11.6
8.2
92.60
79.86
u/l
1.07
126
1104
33
219
1.63
1.62
6.3
7.1
104.27
104.28
mmol/l
0.00
33
219
52
384
1.51
1.61
2.7
2.1
2.48
2.79
mg/l
0.88
46
337
158
1468
1.88
1.54
22.0
16.0
22.37
23.99
mg/l
0.27
140
1211
9
37
2.51
1.50
1.3
1.4
—
—
—
0
0
10
45
2.30
1.49
5.3
2.9
43.00
29.76
mg/l
—
10
40
10
45
2.30
1.49
2.5
1.8
—
—
—
0
0
40
285
1.52
1.46
1.6
1.7
—
—
—
0
0
87
721
1.42
1.45
3.2
3.1
106.65
109.73
ug/l
0.09
81
677
7
29
2.47
1.40
1.9
3.0
15.54
15.92
%
—
7
29
5
17
3.00
1.37
1.2
1.2
—
—
—
0
0
29
197
1.57
1.30
1.7
1.9
—
—
—
0
0
21
132
1.67
1.27
3.0
2.6
0.21
0.22
g/l
0.10
21
122
34
241
1.51
1.27
3.4
3.2
2.14
2.86
e6/l
0.24
15
116
17
101
1.76
1.25
1.1
1.2
149.31
128.38
u/ml
—
8
36
95
815
1.37
1.22
4.1
3.9
0.00
0.00
estimate
-0.00
26
179
57
450
1.40
1.22
3.3
3.3
0.00
0.00
estimate
-0.00
19
146
58
460
1.39
1.21
4.0
3.9
0.00
0.00
estimate
-0.00
22
161
11
57
1.99
1.20
1.3
2.0
0.95
5.98
ug/l
0.52
11
51
10
50
2.06
1.19
1.5
1.3
—
—
—
0
0
94
808
1.36
1.18
3.9
3.9
0.00
0.00
estimate
-0.00
24
176
41
307
1.44
1.17
1.9
1.7
443.50
452.24
pmol/l
0.09
36
261
27
186
1.54
1.15
1.7
1.9
—
—
—
0
0
36
264
1.46
1.14
2.9
3.0
0.63
1.00
e6/l
0.66
17
138
8
40
2.05
1.13
1.8
1.5
—
—
—
0
0
8
40
2.05
1.13
1.6
1.9
—
—
—
0
0
95
822
1.35
1.12
4.1
4.0
0.13
0.02
estimate
0.39
24
164
7
34
2.10
1.04
1.0
1.1
—
—
—
0
0
46
360
1.38
1.02
1.8
1.7
1.15
1.49
mg/l
0.57
41
295
45
353
1.37
0.99
2.8
2.3
—
—
—
0
0
5
23
2.21
0.98
1.2
1.1
—
—
—
0
0
22
152
1.51
0.94
4.6
3.5
—
—
—
0
0
72
613
1.30
0.90
3.8
3.7
0.00
0.01
estimate
0.50
19
153
8
43
1.90
0.88
1.9
1.5
—
—
—
0
0
6
30
2.03
0.88
1.2
1.2
—
—
—
0
0
146
1373
1.41
0.85
6.7
5.3
2.12
1.94
mu/l
0.72
137
1265
53
630
0.77
0.81
2.0
2.0
1.56
1.39
mmol/l
0.66
45
531
24
175
1.43
0.80
5.2
4.6
27.82
32.95
%
1.21
17
112
0
24
0.00
0.80
0.0
1.4
—
—
—
0
0
71
612
1.27
0.79
4.7
4.1
35.83
38.57
ng/l
0.05
47
440
0
26
0.00
0.79
0.0
1.3
—
—
—
0
0
0
26
0.00
0.79
0.0
1.3
—
—
—
0
0
17
116
1.52
0.77
3.6
3.5
82.86
63.53
ml/min/173m2
—
7
49
6
34
1.79
0.77
3.0
2.5
121.33
112.72
ug/min
—
6
19
5
24
2.11
0.75
1.6
1.5
0.19
0.26
nmol/l
—
5
18
7
41
1.74
0.71
4.3
2.7
1.91
1.71
ratio
—
7
19
112
1028
1.25
0.70
3.9
3.1
38.98
46.87
u/l
1.03
107
973
74
649
1.25
0.70
2.5
2.1
92.92
95.73
pmol/l
0.24
32
330
146
1385
1.35
0.69
7.6
6.3
40.26
39.29
mmol/mol
0.63
132
1303
21
155
1.40
0.67
8.3
7.8
—
—
—
0
0
24
182
1.37
0.66
7.1
7.6
1.10
0.96
mmol/l
0.11
19
153
21
157
1.38
0.63
7.9
8.2
123.24
120.61
g/l
0.24
21
152
5
30
1.69
0.62
1.0
1.3
—
—
—
0
0
5
30
1.69
0.62
5.4
3.3
9.20
44.25
u/ml
—
5
30
5
30
1.69
0.62
1.0
1.3
—
—
—
0
0
0
20
0.00
0.61
0.0
1.4
—
—
—
0
0
11
72
1.56
0.60
3.2
4.3
1.35
1.51
%
0.41
11
64
45
379
1.25
0.60
1.5
1.3
0.91
1.65
u/ml
0.80
13
109
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
8
53
1.53
0.59
3.9
1.5
—
—
—
0
0
18
135
1.37
0.53
1.4
1.4
—
—
—
0
0
148
1420
1.29
0.52
5.5
5.0
6.12
5.91
mmol/l
1.02
135
1320
11
76
1.48
0.49
2.7
1.3
—
—
—
0
0
7
48
1.48
0.47
1.0
1.2
—
—
—
0
0
7
50
1.42
0.45
2.0
1.5
—
—
—
0
0
7
50
1.42
0.45
1.6
1.6
—
—
—
0
0
23
185
1.28
0.45
7.5
7.4
5.20
5.10
kpa
0.21
23
176
23
185
1.28
0.45
7.6
7.4
13.03
12.03
kpa
0.43
23
177
152
1470
1.28
0.44
6.4
5.9
2.73
2.71
mmol/l
0.13
142
1367
5
31
1.63
0.43
1.8
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
17.52
—
0
6
5
35
1.44
0.39
1.2
1.7
—
—
—
0
0
34
294
1.19
0.36
3.4
3.1
0.55
0.74
ug/l
0.79
20
201
6
44
1.38
0.35
1.0
1.1
—
13.90
—
0
6
142
1375
1.18
0.32
4.9
4.3
1.36
1.26
mmol/l
1.00
134
1258
14
111
1.28
0.31
1.9
1.5
—
—
—
0
0
10
77
1.32
0.26
1.0
1.0
—
—
—
0
0
5
39
1.29
0.23
1.2
1.6
—
—
—
0
0
14
167
0.82
0.23
1.7
2.0
—
—
—
0
0
97
928
1.10
0.23
3.1
3.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
13.50
—
0
12
5
43
1.17
0.21
1.2
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
53
494
1.11
0.20
4.8
4.1
6.87
10.01
mg/mmol
0.38
33
318
6
48
1.26
0.20
1.7
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
50
1.21
0.20
1.7
1.8
66.67
40.16
nmol/l
—
6
50
6
51
1.18
0.19
1.5
1.3
—
—
—
0
0
147
1444
1.12
0.16
5.6
5.1
4.62
4.63
mmol/l
0.03
138
1346
47
441
1.09
0.16
2.0
1.7
23.83
21.04
nmol/l
0.58
41
374
6
75
0.79
0.16
1.5
1.3
—
—
—
0
0
10
83
1.22
0.16
10.5
7.7
16.06
15.54
%
—
10
78
10
85
1.19
0.12
3.0
3.0
24.99
24.52
mmol/l
—
10
85
14
157
0.88
0.11
1.7
1.9
—
—
—
0
0
51
488
1.06
0.10
5.7
5.5
3.21
2.50
ug/l
0.22
41
431
146
1441
1.08
0.10
5.6
5.0
1.46
1.48
mmol/l
0.27
136
1331
5
44
1.14
0.10
1.8
1.4
—
—
—
0
0
5
44
1.14
0.10
1.0
1.4
—
66.54
—
0
7
6
55
1.09
0.09
1.8
2.2
—
—
—
0
0
7
68
1.03
0.08
6.7
3.4
4163.71
2590.70
u/ml
—
7
57
37
355
1.05
0.06
4.6
3.8
1.02
1.02
kg/l
0.21
29
223
11
100
1.11
0.05
8.5
7.1
24.14
24.92
mmol/l
0.45
11
94
24
230
1.05
0.03
1.5
1.5
—
—
—
0
0
28
270
1.04
0.03
1.3
1.3
1.66
7.35
u/ml
—
8
106
30
293
1.03
0.01
1.3
1.3
13.86
26.46
iu/ml
—
7
90
39
386
1.01
0.00
5.5
4.8
16.94
21.78
%
1.06
16
192
0
8
0.00
0.00
0.0
1.4
—
109.50
—
0
8
5
51
0.98
0.00
1.0
1.5
—
8.26
—
0
14
0
6
0.00
-0.00
0.0
6.7
—
—
—
0
0
9
96
0.93
-0.00
1.8
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
-0.00
1.7
1.6
682.62
878.39
mu/l
—
6
58
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
-0.00
0.0
1.0
—
136.00
—
0
5
8
85
0.94
-0.00
1.6
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
50
1.00
-0.00
1.4
2.0
400.40
300.20
ug/l
—
5
45
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_CONNSOFT_THX and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CONNSOFT_THX | 0.906 [0.64, 1.28] | 0.579 |
| Birth year | 1.0 [0.99, 1.01] | 0.96 |
During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 492 females with CD2_BENIGN_CONNSOFT_THX died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CONNSOFT_THX | 0.943 [0.68, 1.3] | 0.719 |
| Birth year | 0.984 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 322 males with CD2_BENIGN_CONNSOFT_THX died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_CONNSOFT_THX.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.103% | 0.156% |
| 5 | 0.562% | 0.944% |
| 10 | 1.566% | 2.524% |
| 15 | 2.838% | 4.836% |
| 20 | 5.077% | 7.941% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_CONNSOFT_THX – Benign neoplasm: Connective and other soft tissue of thorax
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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