Exposure to excessive natural heat

VWXY20_EXPOS_EXCESSI_NATURAL_HEAT

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — X30 Cause of death: ICD-10 — X30 2 out of 7 registries used, show all original rules.	92
4. Check minimum number of events None	92
5. Include endpoints None	92
6. Filter based on genotype QC (FinnGen only)	80

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 5
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: X30-X39

NAME	VWXY20_EXPOS_EXCESSI_NATURAL_HEAT
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	X30
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	X30
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Exposure to excessive natural heat based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	80	41	39
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	63.54	66.53	60.40

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
81: Matched controls
810

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

X30

ICD-10 Finland

Exposure to excessive natural heat

+∞

113.6

T67.0

ICD-10 Finland

Heatstroke and sunstroke

166.8

13.9

T67.3

ICD-10 Finland

Heat exhaustion, anhydrotic

+∞

11.7

AA1AD

NOMESCO Finland

CT of head and brain

3.5

6.9

165

T67.5

ICD-10 Finland

Heat exhaustion, unspecified

75.6

6.5

N05AH02

ATC

clozapine; systemic

20.0

6.4

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3023368) Bacteria identified in Blood by Culture

212

3.90

8.42

5.8

4.9

—

(3026008) Bacteria identified in Urine by Culture

219

2.91

5.27

4.3

3.6

—

(3037467) Urinalysis macro (dipstick) panel - Urine

480

3.60

4.64

5.7

4.8

—

(3019977) pH of Arterial blood

3.02

4.25

6.9

7.9

7.40

7.42

0.24

(3002173) Hemoglobin [Mass/volume] in Arterial blood

3.19

4.18

7.3

9.0

120.42

121.06

g/l

0.04

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

4.22

3.80

7.5

7.6

15.72

15.43

0.11

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.68

3.45

2.3

1.8

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

197

2.37

3.43

2.7

2.1

2.82

2.95

mg/l

0.12

170

(3047181) Lactate [Moles/volume] in Blood

6.21

3.43

8.4

8.2

1.20

1.05

mmol/l

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.25

3.39

5.0

9.2

23.82

24.61

mmol/l

0.16

(3000991) Gas panel - Venous blood

2.85

3.21

7.8

9.3

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.60

3.18

2.4

1.8

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

7.98

3.11

1.2

1.9

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.53

3.01

2.2

1.8

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

3.10

2.98

4.5

3.6

150.08

204.74

ng/l

0.47

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

309

2.13

2.78

2.9

—

estimate

—

(3039000) Anion gap in Blood by calculation

6.37

2.75

9.5

8.2

10.33

10.50

mmol/l

—

(3018572) Chloride [Moles/volume] in Blood

6.37

2.75

9.7

8.2

103.50

104.40

mmol/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

126

2.29

2.67

2.4

1.9

—

(3042936) Bacteria identified in Isolate by Culture

112

2.32

2.62

2.9

2.0

—

(42870588) Differential panel, method unspecified - Blood

236

2.05

2.50

7.6

5.9

—

(3023520) Reticulocytes [#/volume] in Blood

2.52

2.47

3.1

3.3

57.53

67.57

e9/l

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

3.92

2.43

1.0

—

(3000494) Fungus identified in Specimen by Culture

2.33

2.40

1.1

1.4

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

5.25

2.10

1.2

1.9

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

115

2.12

2.08

3.7

2.8

23.30

23.99

0.11

106

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

362

1.90

2.03

9.2

7.2

1.20

1.21

mmol/l

0.52

304

(1761868) Lipid panel - Serum or Plasma

266

0.46

1.93

2.5

3.3

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

3.38

1.93

2.0

1.5

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

3.38

1.93

2.0

1.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.26

1.89

1.3

1.4

—

(3044290) Cell count panel - Cerebral spinal fluid

3.72

1.87

1.2

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

2.23

1.84

1.2

1.5

—

(3019309) Folate [Moles/volume] in Red Blood Cells

137

1.95

1.80

1.7

846.00

1185.18

nmol/l

1.47

108

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

242

1.79

1.72

2.9

3.5

2453.65

1922.13

ng/l

0.15

200

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

158

1.84

1.63

1.9

2.3

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

2.85

1.62

1.3

1.2

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

671

2.59

1.59

32.0

21.3

3.99

4.00

mmol/l

0.04

658

(3012516) Albumin [Mass/volume] in Urine

211

1.76

1.59

3.1

3.6

65.83

72.50

mg/l

0.05

146

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.58

1.58

1.0

1.2

—

(3006315) Basophils [#/volume] in Blood

363

1.70

1.51

7.9

6.6

0.04

e9/l

0.42

307

(3001604) Monocytes [#/volume] in Blood

363

1.70

1.51

7.9

6.5

0.56

0.61

e9/l

0.98

309

(3024561) Albumin [Mass/volume] in Serum or Plasma

316

1.68

1.48

5.4

5.3

33.70

35.14

g/l

0.90

298

(46235355) HIV 1 and 2 tests - Meaningful Use set

173

1.74

1.42

2.2

2.1

—

(3019198) Lymphocytes [#/volume] in Blood

367

1.67

1.42

8.0

6.6

1.80

1.79

e9/l

0.04

320

(3020682) Albumin/Creatinine [Ratio] in Urine

217

1.69

1.41

3.1

4.5

13.45

11.92

mg/mmol

0.05

148

(40761511) CBC panel - Blood by Automated count

694

2.54

1.39

25.2

15.4

—

(3018418) pH of Serum or Plasma

236

1.67

1.39

6.1

4.1

7.40

0.13

172

(3003191) Choriogonadotropin [Presence] in Serum or Plasma

3.06

1.38

2.2

2.5

—

(3013115) Eosinophils [#/volume] in Blood

370

1.64

1.35

11.0

6.9

0.17

0.19

e9/l

0.35

319

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.50

1.33

3.1

2.4

—

(3044640) Blood type and Crossmatch panel - Blood

220

1.66

1.33

2.0

2.5

—

(3019060) Gas panel - Arterial blood

2.19

1.28

7.2

4.3

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

2.41

1.21

1.0

1.2

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

0.00

1.19

0.0

2.1

—

1.46

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

138

1.70

1.18

2.4

1.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.10

1.17

1.0

1.6

—

(3032080) INR in Blood by Coagulation assay

349

1.57

1.17

25.9

15.7

1.41

1.29

inr

0.61

296

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

147

1.68

1.17

1.5

1.7

—

(3015736) pH of Urine

311

1.57

1.15

4.0

3.8

6.13

6.15

0.05

175

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

2.22

1.08

1.6

1.5

1.42

0.72

ug/l

—

(3027944) Amphetamines [Presence] in Urine

2.16

1.06

5.0

1.5

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

2.35

1.05

2.6

2.4

4.12

3.55

g/l

—

(3026782) Osmolality of Urine

160

1.61

1.04

3.3

3.7

539.77

523.63

mosm/kgh2o

0.17

143

(3027008) Opiates [Presence] in Urine

2.09

1.03

5.0

1.5

—

(3000764) Benzodiazepines [Presence] in Urine

2.09

1.03

5.0

1.5

—

(3028300) Cannabinoids [Presence] in Urine

2.03

0.99

5.0

1.5

—

(36660697) Celiac disease serology panel - Serum

1.90

0.92

1.3

1.2

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.00

0.92

1.1

1.2

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.83

0.91

1.4

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.69

0.88

2.4

1.7

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.65

0.82

1.4

1.8

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.79

0.80

1.6

1.9

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

126

1.55

0.79

5.4

3.6

6.80

1.65

e6/l

—

(4024509) Urine culture

1.82

0.78

3.0

1.7

—

(3003694) ABO and Rh group [Type] in Blood

198

1.46

0.78

1.3

1.5

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

311

1.42

0.77

3.6

4.4

22.90

50.23

ng/l

1.28

241

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.25

0.77

1.4

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

118

1.56

0.77

1.7

1.5

—

(3011288) Drugs identified in Urine by Screen method Nominal

2.15

0.76

4.6

2.2

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.68

0.75

5.3

4.1

114.37

83.54

ng/l

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

421

1.41

0.75

3.5

3.3

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

246

1.42

0.74

2.2

3.7

2.28

2.36

mmol/l

3.23

225

(3002032) Base excess in Venous blood by calculation

1.63

0.74

6.8

4.3

1.28

1.72

mmol/l

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.59

0.72

2.6

2.2

—

(3022313) Gas panel - Capillary blood

1.91

0.69

1.2

2.1

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

416

1.38

0.67

30.3

10.0

4.48

4.29

e9/l

0.24

365

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

106

1.51

0.63

3.6

2.4

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.63

0.63

1.6

2.5

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.71

0.62

3.0

1.4

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.60

0.0

1.4

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.60

0.0

7.7

—

(3016879) Cocaine [Presence] in Urine

1.77

0.59

5.3

1.5

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

621

1.46

0.57

5.9

5.4

1.99

1.93

mu/l

0.08

573

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

314

1.33

0.56

3.2

2.2

93.62

92.27

pmol/l

0.06

160

(3018095) Leukocytes [#/volume] in Urine

296

1.32

0.54

6.0

4.4

22.45

58.33

e6/l

0.98

220

(3014051) Protein [Presence] in Urine by Test strip

211

1.34

0.53

3.0

3.3

—

0.29

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

528

1.35

0.52

4.2

4.3

14.89

14.84

pmol/l

0.04

482

(3009261) Glucose [Presence] in Urine by Test strip

406

1.31

0.52

4.4

4.0

0.00

estimate

—

(3021601) Nitrite [Presence] in Urine by Test strip

397

1.30

0.50

4.2

3.9

0.00

estimate

—

101

(3002582) Erythrocytes [#/volume] in Urine

271

1.30

0.48

5.3

3.7

18.37

28.13

e6/l

0.37

213

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

140

1.37

0.47

5.4

3.3

0.71

0.92

e6/l

—

(3030467) Casts [#/volume] in Urine by Automated count

234

1.30

0.46

5.5

3.6

0.76

0.44

e6/l

0.24

176

(40758558) Short blood count panel - Blood

227

1.28

0.42

16.3

6.2

—

(3035350) Ketones [Presence] in Urine by Test strip

403

1.26

0.42

4.2

3.9

0.00

estimate

—

100

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.41

0.0

1.9

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.41

0.0

1.7

—

16.95

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.41

0.0

4.4

—

23.22

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.41

0.0

2.1

—

237.74

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.41

0.0

1.8

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

242

0.77

0.40

4.3

5.3

1.15

1.76

ug/l

0.82

214

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.50

0.37

1.0

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.43

0.36

1.7

2.3

—

(40761536) Microorganisms panel - Urine sediment

0.67

0.27

9.0

3.3

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.28

0.27

6.4

7.6

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

631

1.25

0.26

6.1

4.9

5.99

5.93

mmol/l

0.12

575

(3022145) Colonoscopy Study observation

1.21

0.26

1.1

1.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.34

0.23

1.4

—

(3000492) Spirometry study

1.30

0.23

2.2

1.6

—

(3013512) EKG study

241

1.18

0.23

4.1

4.0

—

(3018333) Ribosomal P Ab [Presence] in Serum

0.00

0.21

0.0

1.3

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40768795) Lymph node Pathology biopsy report

0.00

0.21

0.0

1.0

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.2

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.21

0.0

1.2

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.21

0.0

1.1

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.21

0.0

1.0

—

(40759850) Jo-1 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.30

0.21

1.3

2.6

5.02

5.04

kpa

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

2.5

—

107.15

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

2.5

—

1.20

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

2.5

—

4.05

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

0.00

0.20

0.0

2.0

—

10.05

—

(40768793) Breast Pathology biopsy report

0.00

0.20

0.0

1.4

—

(3020630) Protein [Mass/volume] in Serum or Plasma

1.14

0.18

2.4

2.7

62.33

66.36

g/l

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

256

1.14

0.17

2.0

1.48

1.41

mmol/l

0.16

215

(3019150) Specific gravity of Urine by Refractometry

169

1.16

0.16

4.4

3.7

1.02

kg/l

—

108

(3041096) Erythrocytes [Presence] in Urine by Automated

231

0.88

0.15

3.5

3.6

0.00

estimate

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.15

0.10

1.2

1.4

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.17

0.10

2.1

1.6

—

(3007164) IgA [Mass/volume] in Serum or Plasma

175

0.89

0.09

1.4

1.3

2.59

2.39

g/l

—

111

(40768804) Tissue Pathology biopsy report

244

1.10

0.09

2.4

2.1

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.82

0.08

2.8

2.1

—

(4035726) Immunohistochemistry procedure

0.78

0.08

1.0

1.3

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.03

0.08

2.1

1.6

11.57

10.25

g/l

—

(40760892) CBC W Ordered Manual Differential panel - Blood

172

0.91

0.06

5.8

6.2

—

(3021589) Normoblasts [#/volume] in Blood

340

0.95

0.03

19.0

13.1

0.00

e9/l

-0.00

273

(40768797) Stomach Pathology biopsy report

1.10

0.03

1.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

305

1.03

0.00

3.8

3.9

0.00

0.01

estimate

—

(3029937) Albumin [Presence] in Urine by Test strip

234

0.98

0.00

4.8

3.7

0.00

estimate

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.6

—

108.20

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(40760543) Extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.1

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

5.3

—

23.53

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

-0.00

0.0

1.2

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

-0.00

0.0

1.1

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

2.6

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.9

—

73.00

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

180.13

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

1.6

—

9.81

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.8

—

4.54

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.93

-0.00

2.6

3.8

—

(4268621) Lupus anticoagulant assay

0.00

-0.00

0.0

2.3

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

-0.00

0.0

4.1

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

2.2

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

2.3

—

0.71

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

-0.00

0.0

1.0

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

-0.00

0.0

4.3

—

32.18

—

(3037534) Parathyrin related protein [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

65.60

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.8

—

9.82

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

5.1

—

3.37

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.3

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

13.9

—

0.60

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

-0.00

0.0

1.1

—

19.57

—

(3002256) Pathology report gross observation

0.96

-0.00

1.4

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

-0.00

0.0

1.4

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3047189) Immunofixation for 24 hour Urine

0.00

-0.00

0.0

1.2

—

(3004451) EKG impression Narrative

0.00

-0.00

0.0

1.4

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

4.8

—

0.40

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.2

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

27.86

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

4.0

—

113.43

—

(3009595) Pneumocystis jirovecii DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(21494755) Public health laboratory ask at order entry panel

1.02

-0.00

1.1

1.3

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

-0.00

0.0

2.0

—

6.93

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.7

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: VWXY20_EXPOS_EXCESSI_NATURAL_HEAT – Exposure to excessive natural heat

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R14

FinnGen R13 + FinRegistry

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Exposure to excessive natural heat

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Exposure to excessive natural heat (VWXY20_EXPOS_EXCESSI_NATURAL_HEAT)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints