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Palindromic rheumatism

DOID EFO Endpoint Browser PheWeb

M13_PALINDROMIC

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M12.3
  • Hospital discharge: ICD-8 — 71220
  • Cause of death: ICD-10 — M12.3
  • Cause of death: ICD-8 — 71220

2 out of 7 registries used, show all original rules.

429

4. Check minimum number of events

None

429

5. Include endpoints

None

429

6. Filter based on genotype QC (FinnGen only)

400

Control definitions (FinnGen only)

Control exclude
M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M12
Name in latin
Rheumatismus palindromicus

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1936 1191 735
Only index persons 1767 1120 647
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.02
Only index persons 0.04 0.04 0.02
Median age at first event (years)
Whole population 52.21 51.50 53.40
Only index persons 51.77 51.02 53.08

-FinnGen-

Key figures

All Female Male
Number of individuals 400 258 142
Unadjusted period prevalence (%) 0.08 0.09 0.07
Median age at first event (years) 52.56 51.07 55.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
403
Matched controls
4030
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P01BA02
ATC
hydroxychloroquine; oral
537.6
307.7
327
32
M12.3
ICD-10 Finland
Palindromic rheumatism
+∞
307.7
369
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
108.9
307.7
275
78
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
210.6
307.7
190
17
L04AX03
ATC
methotrexate; systemic
75.6
307.7
223
65
A07EC01
ATC
sulfasalazine; oral, rectal
58.7
284.7
171
50
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
85.6
277.2
151
28
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3795.9
219.8
192
*
M13.9
ICD-10 Finland
Arthritis, unspecified
49.2
176.0
106
29
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
24.1
136.1
105
58
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
15.7
130.2
131
120
L88
ICPC
Rheumatoid/seropositive arthritis
169.5
109.5
111
9
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
464.2
107.8
103
*
H02AB06
ATC
prednisolone; systemic
9.7
90.6
326
1221
M25.5
ICD-10 Finland
Pain in joint
7.2
87.2
210
532
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
+∞
81.0
75
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
13.2
80.3
84
79
L04AA13
ATC
[U] leflunomide
446.3
76.5
74
*
L01BA01
ATC
methotrexate; systemic
177.6
71.6
73
5
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
783.8
69.2
66
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
+∞
67.6
63
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
120.6
66.3
70
7
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
727.5
64.8
62
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
117.1
56.6
60
6
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
9.7
44.9
56
66
L04AB01
ATC
etanercept; parenteral
464.1
43.0
42
*
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
42.4
40
*
M01CB01
ATC
sodium aurothiomalate; parenteral
+∞
40.3
38
*
M20.1
ICD-10 Finland
Hallux valgus (acquired)
15.4
37.8
34
24
H02AB07
ATC
prednisone; oral
4.9
36.4
95
238
71220
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Palindromic rheumatism
+∞
33.8
32
*
M01AH01
ATC
celecoxib; oral
4.4
33.6
102
287
L20
ICPC
Joint symptom/complaint NOS
9.5
32.5
40
46
M79.0
ICD-10 Finland
Rheumatism, unspecified
10.1
32.3
38
41
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
10.9
32.3
36
36
M19.0
ICD-10 Finland
Primary arthrosis of other joints
11.9
31.5
33
30
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.3
30.3
196
902
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
+∞
29.5
28
*
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
7.4
29.5
45
67
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
46.3
28.2
34
8
NH3EA
NOMESCO Finland
Feet X-ray examination with load
107.8
28.1
30
*
M01AH05
ATC
etoricoxib; oral
3.3
27.5
282
1663
M16.1
ICD-10 Finland
Other primary coxarthrosis
11.5
27.2
29
27
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
26.8
239
1295
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
5.1
26.0
60
134
NF1AA
NOMESCO Finland
Hip X-ray examination
6.5
25.8
45
77
ZX140
NOMESCO Finland
Intra articular
+∞
25.3
24
*
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
+∞
25.3
24
*
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
23.1
25.2
36
17
N02AX02
ATC
tramadol; systemic, rectal
3.0
25.1
196
978
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
22.5
191
982
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
+∞
22.1
21
*
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
22.1
21
*
TNG10
NOMESCO Finland
Puncture of knee
121.7
21.8
23
*
L04AB04
ATC
adalimumab; parenteral
24.8
21.6
30
13
A02BC02
ATC
pantoprazole; systemic
3.0
20.5
308
2082
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.8
20.0
48
110
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
20.0
19
*
L04AK01
ATC
leflunomide; oral
+∞
20.0
19
*
M01CB03
ATC
auranofin; oral
+∞
20.0
19
*
M10.9
ICD-10 Finland
Gout, unspecified
6.9
19.9
32
50
M01AE02
ATC
naproxen; oral, rectal
2.7
19.8
256
1591
M35.3
ICD-10 Finland
Polymyalgia rheumatica
6.6
19.7
33
54
L15
ICPC
Knee symptom/complaint
3.1
19.6
105
417
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
6.6
19.2
32
52
WX320
NOMESCO Finland
Spinalanesthesy
3.1
18.5
95
368
H02AB04
ATC
methylprednisolone; systemic
3.3
18.1
80
283
M13.0
ICD-10 Finland
Polyarthritis, unspecified
187.9
17.7
18
*
L04AX01
ATC
azathioprine; systemic
5.9
17.2
32
58
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
66.3
16.9
19
*
M01AH02
ATC
rofecoxib; oral
3.6
16.7
62
196
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
177.0
16.6
17
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.0
16.4
50
138
N03AX16
ATC
[U] pregabalin
2.8
16.3
99
418
M01AB55
ATC
diclofenac, combinations; oral
4.7
16.1
39
90
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
18.7
15.3
23
13
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
21.1
15.3
22
11
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
46.9
15.2
18
*
M79.6
ICD-10 Finland
Pain in limb
2.3
15.0
185
1081
L04AB06
ATC
golimumab; parenteral
59.0
14.9
17
*
M01AC06
ATC
meloxicam; systemic, rectal
2.4
14.7
155
845
M06
ICD-10 Finland
Other rheumatoid arthritis
+∞
14.7
14
*
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
6.0
14.3
26
46
L28
ICPC
Limited function/disability (L)
2.8
13.7
83
347
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
+∞
13.6
13
*
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
4.0
13.6
41
112
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
144.7
13.5
14
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.1
13.5
39
103
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.2
13.3
58
202
J01DB01
ATC
cefalexin; oral
2.8
13.2
341
2667
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
29.5
13.1
17
6
S18
ICPC
Laceration/cut
2.2
13.0
198
1241
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
12.8
171
1017
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
16.1
12.7
20
13
SPAT1202
SPAT
Intra-articular injection
11.5
12.7
23
21
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
+∞
12.6
12
*
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
12.6
12
*
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
134.0
12.5
13
*
NG1DA
NOMESCO Finland
X-ray of knees
134.0
12.5
13
*
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
10.1
12.4
24
25
M13.8
ICD-10 Finland
Other specified arthritis
38.8
12.3
15
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.4
12.1
103
506
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
11.9
165
988
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
6.1
11.9
21
36
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
11.0
11.9
22
21
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.0
11.9
56
204
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.2
11.8
131
719
B01AF01
ATC
rivaroxaban; oral
3.2
11.6
49
167
J45.9
ICD-10 Finland
Asthma, unspecified
2.4
11.6
92
437
M01AX17
ATC
nimesulide; oral
2.3
11.5
103
515
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
+∞
11.5
11
*
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
+∞
11.5
11
*
7148X
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Other specified inflammatory polyarthropathies
+∞
11.5
11
*
M01AX05
ATC
glucosamine; oral
2.9
11.5
59
225
M79.7
ICD-10 Finland
Fibromyalgia
5.6
11.5
22
41
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.4
11.5
90
425
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
25.9
11.2
15
6
M35.7
ICD-10 Finland
Hypermobility syndrome
20.8
11.2
16
8
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
20.8
11.2
16
8
L11
ICPC
Wrist symptom/complaint
3.1
11.2
51
182
SPAT1059
SPAT
Spirometry at the office
4.2
11.1
30
75
R06AE07
ATC
cetirizine; oral
2.0
10.9
184
1176
M04AA01
ATC
allopurinol; systemic
3.0
10.9
51
185
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
10.8
160
974
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.4
10.8
91
442
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
28.9
10.8
14
5
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.7
10.6
34
97
SPAT1249
SPAT
Treatment-related counselling outside office
2.0
10.5
168
1050
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
+∞
10.5
10
*
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
13.6
10.2
17
13
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
13.6
10.2
17
13
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.2
10.2
21
42
R03BA01
ATC
beclometasone; inhalant
2.6
10.1
64
272
Z01.2
ICD-10 Finland
Dental examination
2.0
10.1
185
1209
SPAT1153
SPAT
Removal of sutures
2.1
10.0
123
695
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
41.2
10.0
12
*
SPAT1211
SPAT
Application of soft bandage
3.3
10.0
40
132
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
12.6
9.9
17
14
M01AB05
ATC
diclofenac; systemic, rectal
2.0
9.7
262
1944
R5110, ,
SPAT
3.2
9.6
40
135
L04AA01
ATC
[U] ciclosporin
15.5
9.6
15
10
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.9
9.5
28
75
M54.5
ICD-10 Finland
Low back pain
2.0
9.5
145
886
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
102.3
9.5
10
*
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
102.3
9.5
10
*
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
30.8
9.4
12
*
NG2AA
NOMESCO Finland
Patella X-ray examination
30.8
9.4
12
*
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
+∞
9.4
9
*
M17.5
ICD-10 Finland
Other secondary gonarthrosis
+∞
9.4
9
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.6
9.4
59
250
A02BC05
ATC
esomeprazole; systemic
1.9
9.2
168
1088
L90
ICPC
Osteoarthrosis of knee
4.8
9.2
21
46
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
9.1
64
285
R03AK07
ATC
formoterol and budesonide; inhalant
2.1
9.1
98
524
WZC30
NOMESCO Finland
Teaching
2.3
9.1
82
408
N02AA05
ATC
oxycodone; systemic
2.3
9.1
75
360
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
9.0
145
898
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.5
9.0
62
274
M02AA10
ATC
ketoprofen; topical
2.4
9.0
68
314
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
12.9
8.9
15
12
L17
ICPC
Foot/toe symptom/complaint
2.0
8.8
119
693
ACC51
NOMESCO Finland
Release of median nerve
3.3
8.7
33
105
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
51.1
8.7
10
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
8.6
197
1364
A02BA02
ATC
ranitidine; systemic
2.2
8.6
83
425
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
8.6
96
521
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.6
8.5
54
229
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
28.2
8.5
11
*
B01AB05
ATC
enoxaparin; parenteral
2.0
8.5
107
606
J01FA01
ATC
erythromycin; systemic
2.5
8.5
57
249
A46
ICD-10 Finland
Erysipelas
2.5
8.5
59
262
L40.5
ICD-10 Finland
Arthropathic psoriasis
91.9
8.4
9
*
P01BA01
ATC
chloroquine; systemic
91.9
8.4
9
*
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
91.9
8.4
9
*
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
5.0
8.4
18
37
L04AA17
ATC
[U] adalimumab
+∞
8.4
8
*
L04AA11
ATC
[U] etanercept
+∞
8.4
8
*
L04AC07
ATC
tocilizumab; parenteral
+∞
8.4
8
*
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
+∞
8.4
8
*
L04AA24
ATC
abatacept; parenteral
+∞
8.4
8
*
M10.0
ICD-10 Finland
Idiopathic gout
9.7
8.3
16
17
J01DA09
ATC
[U] cefadroxil
2.0
8.3
110
634
R03AC02
ATC
salbutamol; inhalant
1.8
8.3
222
1609
L12
ICPC
Hand/finger symptom/complaint
2.2
8.3
75
374
R01AD08
ATC
fluticasone; nasal
2.0
8.2
123
739
M03BX02
ATC
tizanidine; oral
1.9
8.2
248
1864
C03CA01
ATC
furosemide; systemic
2.0
8.1
114
672
J01AA02
ATC
doxycycline; systemic
2.0
8.0
316
2579
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
3.7
8.0
25
70
R52.9
ICD-10 Finland
Pain, unspecified
2.7
8.0
44
174
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
3.1
8.0
33
111
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
8.0
104
596
R03DC03
ATC
montelukast; oral
2.2
7.9
73
367
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
7.8
106
615
L13
ICPC
Hip symptom/complaint
2.2
7.8
70
347
ND2BG
NOMESCO Finland
MRI of hand
45.9
7.7
9
*
SPAT1263
SPAT
Sampling
1.8
7.7
163
1092
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.6
7.7
48
202
NDL52
NOMESCO Finland
Tenosynovectomy of hand
18.8
7.6
11
6
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
4.2
7.6
20
49
J01FA09
ATC
clarithromycin; systemic
1.9
7.6
130
814
-1, ,
NOMESCO Finland
1.9
7.6
134
848
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
4.5
7.5
18
41
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.8
7.5
38
144
M05BA04
ATC
alendronic acid; oral
2.8
7.5
39
150
NDG30
NOMESCO Finland
Fusion of wrist, total
81.5
7.4
8
*
M19.2
ICD-10 Finland
Other secondary arthrosis
81.5
7.4
8
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
7.4
105
617
N02BF02
ATC
pregabalin; oral
3.3
7.4
28
89
M07.3
ICD-10 Finland
Other psoriatic arthropathies
+∞
7.3
7
*
3005
Kela drug reimbursment
Tofacitinib
+∞
7.3
7
*
212
Kela drug reimbursment
Gout
+∞
7.3
7
*
291
Kela drug reimbursment
Tofacitinib
+∞
7.3
7
*
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
+∞
7.3
7
*
M05BA07
ATC
risedronic acid; oral
6.0
7.3
19
33
L01
ICPC
Neck symptom/complaint
2.2
7.3
67
335
SPAT1216
SPAT
Assessment of functional ability
2.2
7.2
64
315
R06.0
ICD-10 Finland
Dyspnoea
1.9
7.2
107
638
M01AH03
ATC
valdecoxib; oral
3.2
7.2
29
96
L08
ICPC
Shoulder symptom/complaint
2.0
7.2
88
491
Z00.0
ICD-10 Finland
General medical examination
2.1
7.2
82
446
SPAT1104
SPAT
Monitoring of emergency patient
3.1
7.2
31
107
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
30.6
7.2
9
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.8
7.1
37
142
M15.8
ICD-10 Finland
Other polyarthrosis
10.3
7.1
13
13
HMAK, ,
NOMESCO Finland
2.3
7.1
56
263
R21
ICPC
Throat symptom/complaint
2.0
7.0
83
458
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
7.0
46
199
J01FA10
ATC
azithromycin; systemic
1.7
7.0
224
1681
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.0
7.0
82
451
M48.0
ICD-10 Finland
Spinal stenosis
2.6
6.9
42
174
RF420, ,
NOMESCO Finland
14.1
6.9
11
8
1XC02, ,
NOMESCO Finland
14.1
6.9
11
8
L16
ICPC
Ankle symptom/complaint
2.5
6.9
47
206
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
8.5
6.9
14
17
XA402
NOMESCO Finland
ENMG
6.3
6.8
17
28
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
9.6
6.8
13
14
Z50.1
ICD-10 Finland
Other physical therapy
3.4
6.8
24
73
RF410, ,
NOMESCO Finland
17.0
6.8
10
6
L03
ICPC
Low back symptom/complaint
1.9
6.7
110
676
NE1BA
NOMESCO Finland
Pelvis extensive X-ray examination
23.0
6.7
9
*
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.0
6.7
30
106
M02AA07
ATC
piroxicam; topical
1.8
6.7
135
885
R05
ICPC
Cough
1.9
6.7
103
621
K03.66
ICD-10 Finland
Tooth plaque
2.7
6.7
35
135
N06AA09
ATC
amitriptyline; systemic
2.6
6.7
38
153
M23.8
ICD-10 Finland
Other internal derangements of knee
8.9
6.6
13
15
N03AX12
ATC
[U] gabapentin; oral
2.2
6.6
56
271
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.7
6.6
37
148
SPAT1097
SPAT
Recording of ECG
2.2
6.5
62
314
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
6.5
103
625
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
6.5
92
538
J45.8
ICD-10 Finland
Mixed asthma
4.0
6.5
18
46
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
6.5
53
252
R02
ICPC
Shortness of breath/dyspnoea
2.3
6.5
53
252
N02BE01
ATC
paracetamol; systemic, rectal
2.2
6.5
350
3039
9531
FHL
Arthrodesis of the hand joint
70.9
6.4
7
*
SPAT1254
SPAT
Administration of medicine
2.2
6.4
58
288
S76
ICPC
Skin infection other
3.1
6.4
27
92
ZX120
NOMESCO Finland
Intravenous
2.4
6.4
43
188
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
6.3
169
1196
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
18.4
6.3
9
5
XX9XE
NOMESCO Finland
Other ultrasound examination
18.4
6.3
9
5
E66.01
ICD-10 Finland
Obesity due to excess calories
2.5
6.3
39
164
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
+∞
6.3
6
*
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
+∞
6.3
6
*
NHG82
NOMESCO Finland
Fusion of other tarsal joint
+∞
6.3
6
*
3006
Kela drug reimbursment
Baricitinib
+∞
6.3
6
*
293
Kela drug reimbursment
Baricitinib
+∞
6.3
6
*
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
6.3
6
*
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
5.2
6.3
18
36
M01AX01
ATC
nabumetone; oral
4.1
6.2
17
43
A02BC03
ATC
lansoprazole; oral
1.8
6.2
115
733
J01FA15
ATC
telithromycin; oral
2.4
6.2
45
204
EB1VA, ,
NOMESCO Finland
2.0
6.1
69
373
WZA10
NOMESCO Finland
Extensive medical or dental certificate
8.8
6.1
12
14
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
6.1
204
1528
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
6.9
6.1
14
21

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
218
442
9.57
117.49
1.9
1.1
69.56
2.69
u/ml
12.34
126
184
69
21
39.44
109.87
1.7
1.0
—
—
—
0
0
212
490
8.02
98.41
1.8
1.2
77.28
16.56
iu/ml
7.96
138
126
167
384
6.72
75.16
1.6
1.2
479.31
485.24
titre
0.02
58
84
327
1651
6.20
52.90
11.9
5.4
0.04
0.04
e9/l
1.28
316
1415
325
1650
6.01
51.70
11.9
5.4
0.59
0.57
e9/l
0.83
314
1408
327
1678
6.03
51.05
11.9
5.4
1.80
1.92
e9/l
0.85
316
1471
307
1517
5.30
49.72
12.1
5.4
0.78
0.69
%
1.98
301
1418
306
1518
5.22
49.03
12.1
5.5
8.90
8.82
%
0.24
301
1424
328
1723
5.86
48.70
12.1
5.6
0.19
0.19
e9/l
0.20
320
1496
306
1544
5.08
47.22
12.1
5.5
27.36
27.67
%
0.22
301
1469
68
110
7.23
41.74
2.0
1.5
4.42
4.41
iu/ml
0.00
21
27
126
363
4.60
40.90
3.9
3.0
4.04
5.58
e9/l
0.81
113
324
332
1919
5.14
39.39
16.0
9.6
3.97
4.07
e9/l
0.42
318
1674
107
292
4.63
36.90
5.7
4.5
0.09
0.11
%
0.13
33
80
183
746
3.66
35.60
3.3
2.5
336.26
338.37
umol/l
0.10
171
665
107
309
4.35
34.07
5.8
4.4
0.59
0.98
%
0.92
32
97
102
291
4.35
32.92
5.3
4.5
0.44
0.66
%
0.54
27
86
99
291
4.18
30.53
6.5
5.0
0.00
0.12
%
0.79
23
73
65
137
5.46
30.17
2.1
2.3
0.00
0.02
estimate
0.49
22
45
31
30
11.11
28.35
1.4
1.3
—
—
—
0
0
211
1060
3.08
27.27
10.8
5.1
—
—
—
0
0
170
765
3.11
26.56
7.7
4.9
—
—
—
0
0
43
74
6.39
24.54
1.3
1.3
2.56
15.69
u/ml
—
5
13
43
75
6.30
24.21
1.3
1.2
3.96
3.12
u/ml
—
5
10
90
297
3.61
23.05
4.3
4.4
7.38
7.36
ph
0.94
77
215
32
14
24.70
22.96
1.6
1.0
—
—
—
0
0
330
2266
3.52
22.45
8.0
4.0
—
1.91
—
0
5
273
1778
2.66
18.71
5.2
3.6
0.07
4.70
estimate
0.49
75
372
73
248
3.37
17.60
4.1
2.9
10.09
10.66
g/l
0.48
65
230
266
1761
2.50
16.79
5.3
3.6
0.00
0.00
estimate
0.50
74
374
78
287
3.13
16.44
2.2
2.2
0.05
0.05
estimate
0.04
22
56
236
1504
2.37
15.88
3.1
2.4
80.87
76.71
nmol/l
1.21
225
1350
264
1786
2.39
15.20
5.4
3.6
0.00
0.03
estimate
1.08
73
353
25
43
6.13
14.16
3.2
2.9
3.62
4.21
e9/l
0.70
25
43
220
1430
2.19
13.23
4.3
3.2
6.15
6.20
ph
0.26
125
843
242
1675
2.11
11.87
7.7
7.4
1.22
1.21
mmol/l
1.81
215
1452
28
65
4.55
11.42
1.0
1.1
—
—
—
0
0
163
997
2.07
10.92
5.6
3.5
0.00
0.00
estimate
0.50
70
347
20
20
10.46
10.63
1.2
1.2
—
—
—
0
0
54
207
2.86
10.41
2.2
2.4
42.90
24.90
au/ml
—
5
19
57
226
2.77
10.32
1.3
1.5
—
—
—
0
0
53
208
2.78
9.77
4.2
3.7
7.42
7.42
ph
0.02
48
175
71
338
2.34
8.74
1.3
1.6
—
—
—
0
0
80
401
2.24
8.73
1.7
1.9
—
—
—
0
0
25
67
3.91
8.48
3.2
2.9
56.04
56.21
%
0.02
25
67
153
996
1.86
7.99
2.0
2.1
98.65
271.66
u/l
1.67
147
949
50
212
2.55
7.90
2.2
1.7
1.13
1.46
g/l
0.83
44
193
151
985
1.85
7.80
4.5
3.1
0.74
0.01
estimate
0.48
68
297
255
1954
1.83
7.69
5.0
5.1
6.40
6.73
mmol/l
2.41
245
1850
112
668
1.94
7.59
1.6
1.6
2.55
2.39
g/l
0.44
73
420
87
479
2.04
7.39
1.4
1.6
—
—
—
0
0
38
145
2.79
7.37
4.3
3.9
—
—
—
0
0
372
3277
2.76
7.29
28.1
14.0
16.71
26.14
mg/l
11.12
357
2607
10
5
20.45
7.16
2.3
1.0
—
—
—
0
0
207
1512
1.76
7.14
15.7
11.4
1.25
1.21
inr
0.55
178
1272
205
1498
1.75
7.02
19.2
10.4
0.00
0.00
e9/l
0.97
185
1216
18
33
5.66
6.69
2.3
5.5
—
—
—
0
0
190
1377
1.72
6.56
5.3
3.4
0.36
0.03
estimate
0.45
69
307
32
121
2.79
6.32
3.8
3.7
324.60
360.21
mg/l
—
10
56
142
962
1.74
6.17
3.6
3.2
1234.90
1177.91
ng/l
0.08
125
818
46
212
2.32
6.06
2.0
2.7
—
—
—
0
0
197
1475
1.66
5.79
6.6
6.7
1.22
1.21
mmol/l
2.06
185
1362
54
281
2.06
5.28
2.7
2.3
0.13
0.64
e6/l
0.96
49
270
26
103
2.63
4.73
1.4
1.4
347.43
281.28
ug/g
0.68
14
65
48
250
2.04
4.69
2.6
2.6
5.98
6.06
ph
0.26
33
163
14
31
4.64
4.60
1.1
1.1
—
—
—
0
0
16
52
3.16
4.13
1.7
4.9
2.78
1.91
%
0.18
16
47
185
1448
1.51
4.02
3.3
2.6
—
—
estimate
—
0
0
154
1165
1.52
3.91
2.9
4.0
2.34
2.36
mmol/l
1.20
141
1063
184
1448
1.50
3.85
5.3
5.3
34.11
35.81
g/l
3.09
172
1377
84
555
1.65
3.80
1.4
1.8
—
—
—
0
0
182
1432
1.49
3.80
2.1
2.0
93.73
96.37
pmol/l
0.32
110
759
116
829
1.56
3.80
2.6
2.0
3.12
2.93
mg/l
0.42
107
701
125
910
1.54
3.76
4.4
4.0
—
—
—
0
0
105
739
1.57
3.66
3.6
2.6
3.73
7.25
e6/l
2.02
98
683
7
9
7.89
3.57
1.0
1.0
—
—
—
0
0
7
9
7.89
3.57
1.0
1.0
—
—
—
0
0
7
9
7.89
3.57
1.0
1.0
—
—
—
0
0
136
1021
1.50
3.51
3.1
2.3
—
—
—
0
0
12
32
3.83
3.41
2.3
2.8
1.77
0.61
mmol/l
0.37
12
32
59
367
1.71
3.34
3.1
2.9
1.65
1.84
%
1.08
52
331
13
38
3.50
3.34
1.6
1.8
—
—
—
0
0
61
386
1.68
3.25
1.3
1.3
—
—
—
0
0
48
284
1.78
3.23
1.9
3.1
65.73
71.31
e9/l
0.76
43
217
162
1279
1.45
3.17
4.7
3.6
23.61
35.46
ng/l
1.28
124
911
172
1374
1.44
3.16
2.5
2.1
—
—
—
0
0
77
527
1.57
3.00
1.5
1.6
1003.41
1212.07
nmol/l
1.33
65
403
15
57
2.69
3.00
1.4
1.2
—
—
—
0
0
62
403
1.64
2.98
2.3
2.2
128.03
128.37
ug/g
0.00
51
312
26
129
2.09
2.93
1.3
1.3
—
—
—
0
0
6
9
6.75
2.87
1.2
1.1
244.83
297.82
iu/ml
—
6
9
216
1819
1.40
2.86
7.3
7.2
10.89
11.68
umol/l
0.22
208
1746
154
1228
1.41
2.78
4.9
3.6
172.12
95.20
e6/l
0.23
114
857
100
736
1.48
2.77
1.9
1.5
0.97
1.39
mg/l
1.07
82
572
123
944
1.44
2.74
1.9
1.6
19.75
20.64
nmol/l
0.29
104
787
347
3213
1.58
2.57
6.1
6.0
38.19
39.23
mmol/mol
1.58
331
2990
53
346
1.61
2.52
1.6
1.5
—
—
—
0
0
104
786
1.44
2.49
1.2
1.3
0.55
1.95
u/ml
1.43
31
212
45
286
1.65
2.38
4.5
8.1
10.98
9.23
mmol/l
0.60
45
272
26
142
1.89
2.29
2.4
1.9
—
—
—
0
0
8
23
3.53
2.28
1.5
2.1
104.50
90.54
ng/l
—
8
23
7
18
3.94
2.26
1.1
1.2
—
—
—
0
0
260
2307
1.36
2.25
3.9
3.2
46.04
49.99
u/l
0.43
250
2173
339
3148
1.48
2.21
6.1
5.2
1.89
1.96
mu/l
0.53
325
2888
139
1127
1.36
2.17
4.0
4.0
21.37
10.30
mg/mmol
0.52
90
699
12
49
2.49
2.12
1.3
1.2
38.31
60.52
mu/l
0.32
12
43
57
396
1.51
2.08
1.4
1.5
—
—
—
0
0
39
250
1.62
2.01
2.7
3.9
79.19
84.46
ng/l
0.17
34
223
212
2393
0.76
2.01
3.8
3.8
—
0.00
—
0
5
135
1103
1.34
1.98
3.5
3.3
84.91
53.42
mg/l
0.47
90
694
132
1075
1.34
1.97
4.0
3.1
13.26
57.23
e6/l
3.28
111
816
7
21
3.37
1.97
1.3
4.6
7.76
8.26
mmol/l
—
7
21
93
717
1.39
1.97
1.6
1.7
455.58
31353568.82
pmol/l
0.77
80
606
9
33
2.77
1.94
2.0
1.3
21.03
32.04
ng/l
—
9
33
6
17
3.57
1.84
1.2
1.1
—
—
—
0
0
141
1171
1.31
1.82
3.4
3.2
6.85
7.52
mmol/l
1.15
131
1006
21
117
1.84
1.78
1.6
1.2
—
—
—
0
0
15
281
0.52
1.77
1.4
1.8
3.82
3.49
mmol/l
—
9
205
364
3462
1.53
1.77
22.6
16.9
139.73
139.74
mmol/l
0.02
358
3379
244
2187
1.29
1.74
5.3
4.3
814.00
1425.05
e6/l
—
5
37
8
30
2.70
1.73
1.3
1.2
—
—
—
0
0
61
448
1.43
1.70
1.3
1.2
—
—
—
0
0
364
3468
1.51
1.68
22.9
17.0
3.98
3.96
mmol/l
0.85
359
3379
6
19
3.19
1.66
2.2
4.8
16.18
17.52
%
—
6
19
5
133
0.37
1.65
2.0
1.6
20.20
20.93
s
—
5
123
5
14
3.60
1.62
1.0
1.4
153.40
156.62
mmol/24h
—
5
14
10
43
2.36
1.60
2.3
1.5
9.50
10.88
mmol/l
—
10
43
374
3591
1.58
1.58
24.5
10.8
24.69
25.49
u/l
0.68
374
3473
37
250
1.53
1.57
5.1
3.1
—
—
—
0
0
6
21
2.88
1.51
1.3
1.1
66.00
80.00
umol/l
—
6
21
19
110
1.76
1.45
2.6
4.1
28.39
47.40
mg/l
0.54
14
96
19
110
1.76
1.45
2.6
4.1
35.90
43.83
mg/l
0.35
14
95
18
103
1.78
1.43
2.7
3.4
1.31
5.60
ratio
0.62
11
57
287
2659
1.28
1.41
5.1
4.3
15.15
14.76
pmol/l
1.78
274
2424
14
74
1.92
1.40
1.6
2.9
7.71
8.43
pmol/l
0.14
14
74
11
53
2.11
1.39
1.2
1.1
1.90
2.85
u/ml
—
6
25
118
990
1.27
1.37
4.2
4.2
7.40
7.40
ph
0.17
95
707
110
915
1.28
1.36
3.6
2.9
0.24
0.65
e6/l
1.95
86
663
38
268
1.46
1.34
4.8
3.4
—
—
—
0
0
36
253
1.46
1.29
1.1
1.1
—
—
—
0
0
9
44
2.07
1.27
3.3
2.7
—
—
—
0
0
14
77
1.85
1.27
1.3
1.2
10.81
11.07
u/l
—
7
63
25
368
0.66
1.22
1.3
1.6
—
—
—
0
0
17
273
0.61
1.21
1.3
1.6
—
—
—
0
0
61
480
1.32
1.15
1.4
1.3
—
—
—
0
0
7
32
2.21
1.08
1.9
2.3
—
—
—
0
0
352
3384
1.32
1.05
5.3
5.0
4.66
4.72
mmol/l
0.53
339
3170
338
3233
1.28
1.05
4.7
4.1
1.28
1.26
mmol/l
0.23
322
2977
357
3440
1.33
1.04
5.6
5.6
2.70
2.77
mmol/l
0.77
345
3206
13
75
1.76
1.04
3.4
4.4
—
—
—
0
0
7
36
1.96
0.97
2.4
2.3
—
—
—
0
0
23
158
1.48
0.96
1.0
1.1
—
—
—
0
0
13
78
1.69
0.92
2.1
1.9
—
—
—
0
0
49
387
1.30
0.92
2.1
4.5
3.39
32.51
ug/l
0.93
40
324
350
3375
1.28
0.92
5.2
4.9
1.50
1.50
mmol/l
0.09
337
3133
79
664
1.24
0.90
3.0
3.0
2.46
2.46
mmol/l
0.15
73
603
6
29
2.08
0.89
1.0
1.2
—
—
—
0
0
8
42
1.92
0.89
1.3
1.5
—
—
—
0
0
24
331
0.71
0.87
1.3
1.4
—
—
—
0
0
344
3315
1.26
0.87
5.2
4.8
5.82
5.92
mmol/l
0.88
325
3054
8
44
1.83
0.86
2.8
2.5
32.00
31.95
pg
—
8
44
43
338
1.30
0.85
1.1
1.4
—
—
—
0
0
92
795
1.20
0.81
5.7
3.6
1.02
1.02
kg/l
0.09
72
521
110
968
1.19
0.79
10.6
6.3
—
—
—
0
0
22
157
1.42
0.78
2.4
2.3
—
—
—
0
0
11
67
1.66
0.76
4.6
3.1
—
—
—
0
0
23
167
1.40
0.75
3.9
3.3
1.02
1.02
ratio
0.12
23
156
5
25
2.01
0.73
1.2
1.0
—
—
—
0
0
68
577
1.21
0.72
3.5
3.4
0.80
0.82
mmol/l
1.19
62
552
5
26
1.93
0.71
3.6
5.4
66.40
141.58
nmol/l
—
5
26
9
145
0.61
0.70
4.4
5.2
0.69
0.88
%
—
9
137
377
3694
1.32
0.65
39.4
21.4
133.91
134.98
g/l
0.82
377
3644
128
1405
0.87
0.63
3.2
3.2
—
—
—
0
0
15
210
0.70
0.62
3.6
3.1
135.73
128.88
g/l
0.65
15
203
0
20
0.00
0.60
0.0
1.2
—
12.89
—
0
14
13
185
0.69
0.59
19.3
11.4
16.52
15.74
%
0.41
13
179
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
6
36
1.68
0.57
2.0
2.4
—
—
—
0
0
9
64
1.42
0.52
1.2
1.1
—
—
—
0
0
9
64
1.42
0.52
1.2
1.1
—
—
—
0
0
7
45
1.57
0.49
1.6
1.1
—
—
—
0
0
20
252
0.78
0.45
1.4
1.3
54.83
152.08
u/ml
—
8
95
16
207
0.76
0.44
4.4
4.6
—
—
—
0
0
38
323
1.19
0.43
1.7
1.4
—
—
—
0
0
5
31
1.62
0.43
1.6
1.1
—
—
—
0
0
6
91
0.65
0.43
1.0
1.6
—
—
—
0
0
33
390
0.83
0.42
9.9
8.6
7.42
7.42
ph
0.12
19
227
0
15
0.00
0.41
0.0
7.4
—
0.69
—
0
15
0
15
0.00
0.41
0.0
3.6
—
—
—
0
0
22
177
1.26
0.41
1.2
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
2.1
—
—
—
0
0
5
34
1.48
0.40
1.4
1.1
127.20
110.09
pmol/l
—
5
34
20
160
1.26
0.39
4.5
3.2
24.92
25.05
mmol/l
0.07
20
155
123
1146
1.11
0.39
3.0
3.4
46.40
33.58
u/l
0.58
117
1090
12
158
0.75
0.38
1.0
1.1
—
—
—
0
0
28
235
1.21
0.37
2.0
2.9
125.09
173.21
ng/l
0.39
23
219
13
99
1.32
0.36
2.9
7.3
1.14
1.23
mmol/l
0.27
13
88
9
121
0.74
0.35
1.4
1.4
—
—
—
0
0
6
42
1.43
0.35
2.7
2.5
105.00
105.02
mmol/l
—
6
42
6
42
1.43
0.35
2.7
2.5
1.24
1.20
mmol/l
—
6
42
6
42
1.43
0.35
2.7
2.5
3.85
4.01
mmol/l
—
6
42
17
210
0.80
0.34
3.8
6.6
24.10
24.52
mmol/l
0.17
17
202
6
45
1.34
0.34
1.3
1.4
—
—
—
0
0
28
327
0.85
0.33
10.9
9.4
124.79
122.31
g/l
0.24
28
322
20
240
0.82
0.31
1.3
1.2
—
—
—
0
0
7
98
0.71
0.31
1.0
1.6
—
—
—
0
0
7
100
0.69
0.31
1.0
1.5
—
—
—
0
0
7
100
0.69
0.31
1.0
1.5
—
—
—
0
0
7
100
0.69
0.31
1.0
1.5
—
—
—
0
0
38
335
1.15
0.30
1.4
1.5
—
—
—
0
0
8
62
1.30
0.28
1.0
1.0
—
—
—
0
0
8
62
1.30
0.28
1.0
1.2
—
—
—
0
0
8
62
1.30
0.28
1.1
1.2
—
—
—
0
0
9
117
0.76
0.28
8.7
9.4
—
—
—
0
0
8
64
1.25
0.27
1.3
1.0
—
—
—
0
0
5
72
0.69
0.26
1.4
1.9
—
—
—
0
0
10
127
0.78
0.26
1.1
1.2
0.81
0.91
g/l
—
10
127
9
77
1.17
0.24
1.1
1.2
—
—
—
0
0
98
925
1.08
0.24
5.4
5.1
2.36
3.05
ug/l
0.62
90
832
15
179
0.83
0.23
3.5
2.6
1.18
1.30
%
0.24
15
179
38
343
1.12
0.23
3.8
3.5
5.90
5.75
kpa
0.54
38
331
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
3.4
—
0.59
—
0
11
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
50.76
—
0
10
8
103
0.77
0.21
1.1
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
10
121
0.82
0.18
1.1
1.1
1.56
1.57
g/l
—
10
121
26
287
0.90
0.16
3.7
2.8
4.49
4.52
kpa
0.02
26
275
48
513
0.93
0.16
3.1
2.6
2.70
3.01
e6/l
0.08
22
235
6
76
0.79
0.15
1.0
1.6
—
—
—
0
0
36
388
0.92
0.14
9.2
8.6
1.10
0.92
mmol/l
0.12
31
320
29
315
0.91
0.14
2.1
2.4
32.08
35.59
u/l
0.28
24
269
53
560
0.94
0.13
4.0
3.0
0.66
0.85
ug/l
1.41
44
351
141
1449
0.96
0.13
1.9
1.9
1.38
1.32
mmol/l
0.45
127
1197
10
117
0.85
0.13
1.1
1.1
—
0.69
—
0
20
15
169
0.88
0.13
4.3
4.8
1.33
1.49
%
0.87
15
160
36
336
1.08
0.12
3.8
3.6
7.38
7.38
ph
0.11
23
195
10
85
1.18
0.12
1.7
4.3
25.80
35.05
umol/l
—
10
75
19
209
0.90
0.11
2.1
3.3
34.26
122.06
u/ml
0.85
19
202
26
281
0.92
0.11
12.0
9.8
—
—
—
0
0
11
96
1.15
0.10
1.1
1.3
—
—
—
0
0
5
45
1.11
0.10
1.0
1.8
—
—
—
0
0
349
3469
1.05
0.08
20.3
12.9
—
—
—
0
0
8
90
0.89
0.07
1.6
1.1
—
—
—
0
0
64
622
1.03
0.06
3.4
3.8
437.29
427.01
ng/l
0.01
40
473
10
91
1.10
0.04
2.2
2.8
0.80
2.78
index
—
5
46
18
189
0.95
0.03
1.6
1.6
—
—
—
0
0
104
1030
1.01
0.02
3.9
2.9
—
—
—
0
0
10
93
1.08
0.02
2.4
2.0
825.14
4367.33
u/l
—
5
37
97
977
0.99
0.01
1.4
1.4
—
—
—
0
0
5
50
1.00
0.00
1.6
1.6
—
—
—
0
0
5
50
1.00
0.00
1.6
1.6
—
—
—
0
0
5
50
1.00
0.00
1.6
1.6
—
—
—
0
0
5
50
1.00
0.00
1.6
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
74.24
—
0
5
12
120
1.00
-0.00
1.8
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
0.02
—
0
6
5
51
0.98
-0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
59.40
—
0
5
6
66
0.91
-0.00
3.2
1.8
161.50
208.17
pmol/l
—
6
59
8
89
0.90
-0.00
3.1
4.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
8.68
—
0
5
5
52
0.96
-0.00
1.2
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
7.1
—
25.64
—
0
8
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint M13_PALINDROMIC and mortality.

Females

Parameter HR [95% CI] p-value
M13_PALINDROMIC 1.065 [0.85, 1.33] 0.575
Birth year 0.998 [0.99, 1.01] 0.617

During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 915 females with M13_PALINDROMIC died.

Males

Parameter HR [95% CI] p-value
M13_PALINDROMIC 1.457 [1.19, 1.78] < 0.001
Birth year 0.988 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 120 out of 583 males with M13_PALINDROMIC died.

Mortality risk

Mortality risk for people of age

years, who have M13_PALINDROMIC.

N-year risk Females Males
1 0.084% 0.246%
5 0.568% 1.694%
10 1.612% 4.199%
15 3.344% 7.854%
20 5.978% 13.26%

Relationships between endpoints

↥

Index endpoint: M13_PALINDROMIC – Palindromic rheumatism

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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