Other specific arthropathies, wide

ARTHRO_SPEC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

928

6. Filter based on genotype QC (FinnGen only)

855

Control definitions (FinnGen only)

Control exclude
RHEUMA_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5330 2986 2302
Only index persons 4747 2725 2022
Unadjusted period prevalence (%)
Whole population 0.08 0.09 0.06
Only index persons 0.09 0.10 0.08
Median age at first event (years)
Whole population 47.23 48.64 45.31
Only index persons 45.54 47.24 43.26

-FinnGen-

Key figures

All Female Male
Number of individuals 855 542 313
Unadjusted period prevalence (%) 0.17 0.19 0.14
Median age at first event (years) 47.99 46.84 49.99

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
873
Matched controls
8730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M12.3
ICD-10 Finland
Palindromic rheumatism
+∞
307.7
369
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
98.1
307.7
386
70
A07EC01
ATC
sulfasalazine; oral, rectal
51.2
307.7
258
71
L04AX03
ATC
methotrexate; systemic
50.5
307.7
318
98
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
52.0
307.7
228
59
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
70.2
307.7
262
53
P01BA02
ATC
hydroxychloroquine; oral
113.1
307.7
404
66
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
1687.2
264.7
244
*
M13.9
ICD-10 Finland
Arthritis, unspecified
27.3
257.8
185
85
M17.1
ICD-10 Finland
Other primary gonarthrosis
15.8
249.8
243
208
M12.2
ICD-10 Finland
Villonodular synovitis (pigmented)
+∞
190.8
176
*
L88
ICPC
Rheumatoid/seropositive arthritis
483.8
165.5
160
*
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
92.8
160.1
84
10
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
11.6
158.4
181
193
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
265.6
135.1
135
6
7192F
ICD-9 Finland
Other and unspecified disorder of joint, Villonodular synovitis[SYNOVITIS VILLONODULARIS, POLVI]
+∞
133.9
125
*
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
130.6
122
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
50.4
127.2
74
16
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
8.1
126.1
194
298
L01BA01
ATC
methotrexate; systemic
345.8
120.5
119
*
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
10.4
119.2
143
161
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
1139.0
105.6
101
*
1220
FHL
Arthroscopy
13.1
105.0
105
90
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
+∞
103.2
97
*
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
13.1
103.2
103
88
L04AA13
ATC
[U] leflunomide
1100.8
102.3
98
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
554.4
101.8
99
*
H02AB06
ATC
prednisolone; systemic
4.3
93.9
570
2670
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
6.8
89.9
157
272
M25.5
ICD-10 Finland
Pain in joint
4.0
89.4
430
1702
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
938.7
88.3
85
*
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
9.7
72.0
88
100
L04AB04
ATC
adalimumab; parenteral
32.3
70.6
46
15
M16.1
ICD-10 Finland
Other primary coxarthrosis
12.0
69.2
72
65
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
99.5
67.0
73
8
M12.8
ICD-10 Finland
Other specific arthropathies, not elsewhere classified
+∞
62.2
59
*
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
13.4
61.2
59
47
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
5.2
60.1
137
301
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
98.6
58.7
64
7
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
15.9
58.4
51
34
L04AB01
ATC
etanercept; parenteral
+∞
56.9
54
*
M01AH01
ATC
celecoxib; oral
3.9
56.7
205
641
WX320
NOMESCO Finland
Spinalanesthesy
3.5
56.2
248
885
NH3EA
NOMESCO Finland
Feet X-ray examination with load
22.0
53.5
40
19
M01CB01
ATC
sodium aurothiomalate; parenteral
549.9
53.1
52
*
M35.3
ICD-10 Finland
Polymyalgia rheumatica
12.9
49.9
49
40
M12.0
ICD-10 Finland
Chronic postrheumatic arthropathy [Jaccoud]
+∞
45.2
43
*
L90
ICPC
Osteoarthrosis of knee
8.2
45.1
62
81
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
4.6
44.4
116
283
L15
ICPC
Knee symptom/complaint
3.0
43.8
255
1055
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
157.9
43.2
45
*
M09AX01
ATC
hyaluronic acid; parenteral
9.5
42.9
52
58
M01AH05
ATC
etoricoxib; oral
2.8
42.5
612
3981
N02AX02
ATC
tramadol; systemic, rectal
2.6
41.5
425
2335
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
10.3
40.4
46
47
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
6.5
39.2
66
108
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
11.6
38.2
40
36
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
37.8
36
*
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
12.9
36.8
36
29
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
7.4
36.8
55
79
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
56.4
36.7
43
8
NF1AA
NOMESCO Finland
Hip X-ray examination
5.0
36.5
82
176
H02AB07
ATC
prednisone; oral
3.3
36.1
155
532
TNG10
NOMESCO Finland
Puncture of knee
132.3
36.0
38
*
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
+∞
35.7
34
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.4
34.9
418
2415
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
5.0
34.8
79
171
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
13.8
34.1
32
24
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
33.9
341
1817
71220
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Palindromic rheumatism
+∞
33.6
32
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
33.4
454
2754
SPAT1202
SPAT
Intra-articular injection
9.5
33.2
40
44
1222
FHL
Arthroscopy and synovial surgery
36.7
33.1
42
12
M79.0
ICD-10 Finland
Rheumatism, unspecified
7.4
32.5
48
68
ZX140
NOMESCO Finland
Intra articular
91.1
32.0
35
*
M01AH02
ATC
rofecoxib; oral
3.3
31.7
137
470
A02BC02
ATC
pantoprazole; systemic
2.5
30.9
639
4579
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
33.9
30.2
39
12
B01AB05
ATC
enoxaparin; parenteral
2.4
30.1
269
1346
M01AE02
ATC
naproxen; oral, rectal
2.3
29.6
537
3607
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
29.3
402
2410
N03AX16
ATC
[U] pregabalin
2.5
28.7
224
1050
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
+∞
28.3
27
*
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
28.3
27
*
M01AX05
ATC
glucosamine; oral
2.9
28.2
153
597
M79.6
ICD-10 Finland
Pain in limb
2.2
27.2
413
2556
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
3.7
27.2
92
269
1221
FHL
Arthroscopy and meniscus surgery
8.3
27.0
36
45
M01CB03
ATC
auranofin; oral
279.3
26.9
27
*
B01AF01
ATC
rivaroxaban; oral
3.3
26.4
107
352
NGF10
NOMESCO Finland
Total synovectomy of knee, open
+∞
26.2
25
*
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
7.9
26.1
36
47
M10.9
ICD-10 Finland
Gout, unspecified
5.1
26.1
57
119
L20
ICPC
Joint symptom/complaint NOS
5.3
25.9
54
108
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
74.7
25.9
29
*
L04AK01
ATC
leflunomide; oral
268.2
25.8
26
*
S18
ICPC
Laceration/cut
2.1
25.7
427
2718
M01AC06
ATC
meloxicam; systemic, rectal
2.2
25.6
341
1993
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
8.5
25.4
33
40
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
31.1
25.1
33
11
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
133.8
24.7
26
*
M01AB55
ATC
diclofenac, combinations; oral
3.9
24.7
75
203
NG1DA
NOMESCO Finland
X-ray of knees
49.9
24.4
29
6
H02AB04
ATC
methylprednisolone; systemic
2.7
24.4
149
616
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.0
24.0
119
440
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
69.5
23.9
27
*
M79.7
ICD-10 Finland
Fibromyalgia
7.2
23.9
36
52
L04AB06
ATC
golimumab; parenteral
89.3
23.8
26
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
42.7
23.7
29
7
L04AX01
ATC
azathioprine; systemic
5.0
23.2
51
107
M12.5
ICD-10 Finland
Traumatic arthropathy
+∞
23.0
22
*
WX111
NOMESCO Finland
Local infiltration anesthesia
66.9
22.9
26
*
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
3.2
22.9
99
338
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
3.4
22.8
88
280
9311
FHL
Knee cleansing surgery (synovectomy, debridement)
235.9
22.7
23
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
123.3
22.7
24
*
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.0
22.6
109
396
M23.8
ICD-10 Finland
Other internal derangements of knee
5.4
22.4
45
87
M13.0
ICD-10 Finland
Polyarthritis, unspecified
53.5
22.2
26
5
M45
ICD-10 Finland
Ankylosing spondylitis
64.2
22.0
25
*
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
61.6
21.0
24
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.4
20.8
80
254
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
112.7
20.7
22
*
M01AX17
ATC
nimesulide; oral
2.2
20.3
215
1132
M17.5
ICD-10 Finland
Other secondary gonarthrosis
49.3
20.2
24
5
L28
ICPC
Limited function/disability (L)
2.4
19.6
161
761
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
7.6
19.6
28
38
M35.7
ICD-10 Finland
Hypermobility syndrome
41.1
19.6
24
6
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.5
19.0
68
206
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
18.6
138
622
M01AE03
ATC
ketoprofen; systemic, rectal
1.9
18.5
325
2046
M10.0
ICD-10 Finland
Idiopathic gout
7.0
18.3
28
41
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
22.3
18.3
26
12
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
27.4
17.9
24
9
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
97.1
17.6
19
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
17.6
342
2218
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
29.5
17.5
23
8
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
14.2
17.4
29
21
ZXA05
NOMESCO Finland
Left side
2.1
17.2
204
1114
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
7.0
17.0
26
38
L04AA01
ATC
[U] ciclosporin
19.8
16.9
25
13
NG2AA
NOMESCO Finland
Patella X-ray examination
13.0
16.7
29
23
L04AA17
ATC
[U] adalimumab
+∞
16.7
16
*
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
+∞
16.7
16
*
M06
ICD-10 Finland
Other rheumatoid arthritis
91.9
16.6
18
*
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
4.3
16.2
42
101
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
6.3
16.0
27
44
J01DB01
ATC
cefalexin; oral
2.1
15.8
717
5990
L40.5
ICD-10 Finland
Arthropathic psoriasis
34.1
15.8
20
6
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
15.7
226
1318
L04AA11
ATC
[U] etanercept
+∞
15.7
15
*
7164A
ICD-9 Finland
Other and unspecified arthropathies, Transient arthropathy
+∞
15.7
15
*
M13.8
ICD-10 Finland
Other specified arthritis
22.5
15.6
22
10
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
3.3
15.6
59
185
M15.8
ICD-10 Finland
Other polyarthrosis
6.3
15.5
26
42
L13
ICPC
Hip symptom/complaint
2.2
15.4
152
771
M01AX01
ATC
nabumetone; oral
4.2
15.3
41
101
A46
ICD-10 Finland
Erysipelas
2.3
15.2
128
608
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
15.2
324
2141
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
45.9
15.1
18
*
N02AA05
ATC
oxycodone; systemic
2.2
15.0
150
764
SPAT1153
SPAT
Removal of sutures
1.9
15.0
255
1569
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.1
15.0
66
227
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
4.1
14.9
41
103
1225
FHL
Arthroscopy and other therapeutic procedure
11.6
14.8
27
24
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
57.7
14.8
17
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.9
14.8
218
1279
M01AH03
ATC
valdecoxib; oral
3.2
14.7
60
197
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
14.7
300
1953
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.3
14.7
58
187
M02AA07
ATC
piroxicam; topical
1.8
14.5
304
1991
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
152.5
14.5
15
*
R06.0
ICD-10 Finland
Dyspnoea
1.9
14.5
231
1390
M01AB05
ATC
diclofenac; systemic, rectal
1.8
14.5
571
4486
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.0
14.4
68
243
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.6
14.4
91
379
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.8
14.3
72
267
N02BE01
ATC
paracetamol; systemic, rectal
2.3
14.3
771
6697
XX9XE
NOMESCO Finland
Other ultrasound examination
43.2
14.1
17
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
6.8
14.1
22
33
N02AC04
ATC
dextropropoxyphene; oral
3.9
14.0
41
108
L99
ICPC
Musculoskeletal disease other
5.3
14.0
28
54
SPAT1229
SPAT
Assessment of need for aid
3.0
13.9
62
215
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.8
13.7
72
273
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
5.2
13.7
28
55
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
76.4
13.6
15
*
L04AC07
ATC
tocilizumab; parenteral
+∞
13.6
13
*
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
3.6
13.5
45
130
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
4.2
13.4
36
89
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
21.5
13.4
19
9
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
13.3
320
2171
M05BA04
ATC
alendronic acid; oral
2.7
13.2
73
284
N06AA09
ATC
amitriptyline; systemic
2.5
13.1
85
358
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
4.0
12.9
37
96
L17
ICPC
Foot/toe symptom/complaint
1.8
12.9
255
1632
A02BC05
ATC
esomeprazole; systemic
1.7
12.9
346
2416
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
12.9
82
343
ZXA00
NOMESCO Finland
Right side
1.9
12.8
205
1228
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
5.9
12.8
23
40
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
4.5
12.7
31
71
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
4.7
12.7
29
63
M07.3
ICD-10 Finland
Other psoriatic arthropathies
70.9
12.6
14
*
L04AA24
ATC
abatacept; parenteral
+∞
12.5
12
*
71320
ICD-8 Finland
Osteo-arthritis and allied conditions, Traumatic spondylopathy
+∞
12.5
12
*
7148X
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Other specified inflammatory polyarthropathies
+∞
12.5
12
*
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
5.7
12.5
23
41
TQW40
NOMESCO Finland
Remowal of suture of skin
2.7
12.5
70
275
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.3
12.4
104
492
N03AX12
ATC
[U] gabapentin; oral
2.1
12.3
130
674
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
12.3
225
1405
M48.0
ICD-10 Finland
Spinal stenosis
2.3
12.1
94
430
M04AA01
ATC
allopurinol; systemic
2.4
12.1
87
385
C03CA01
ATC
furosemide; systemic
1.8
12.1
220
1371
J01AA02
ATC
doxycycline; systemic
1.8
12.0
673
5680
M25.4
ICD-10 Finland
Effusion of joint
9.1
11.8
24
27
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
11.7
249
1620
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
11.7
171
994
M54.5
ICD-10 Finland
Low back pain
1.7
11.5
305
2107
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
11.5
203
1251
M02AA10
ATC
ketoprofen; topical
2.0
11.4
137
743
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
4.1
11.3
31
78
M22.4
ICD-10 Finland
Chondromalacia patellae
4.1
11.3
31
78
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
11.3
166
966
Z50.1
ICD-10 Finland
Other physical therapy
3.0
11.2
49
168
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.5
11.2
74
315
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
11.1
156
893
M19.2
ICD-10 Finland
Other secondary arthrosis
10.2
11.0
21
21
E66.01
ICD-10 Finland
Obesity due to excess calories
2.3
10.9
83
376
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.0
10.9
125
668
A02BA02
ATC
ranitidine; systemic
1.9
10.8
164
963
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.8
10.8
54
200
L12
ICPC
Hand/finger symptom/complaint
1.9
10.7
154
889
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.7
10.6
33
91
L03
ICPC
Low back symptom/complaint
1.7
10.6
241
1593
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
3.0
10.5
47
163
M03BX02
ATC
tizanidine; oral
1.6
10.5
534
4304
J01FA10
ATC
azithromycin; systemic
1.6
10.5
485
3820
M01AE11
ATC
tiaprofenic acid; oral, rectal
3.5
10.5
36
106
NGC00
NOMESCO Finland
Exchange of a loose part of prosthesis in knee joint
+∞
10.4
10
*
L04AB05
ATC
certolizumab pegol; parenteral
+∞
10.4
10
*
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
32.9
10.3
13
*
NDG30
NOMESCO Finland
Fusion of wrist, total
32.9
10.3
13
*
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
23.7
10.3
14
6
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
10.3
308
2184
L89
ICPC
Osteoarthrosis of hip
7.6
10.2
23
31
J01FF01
ATC
clindamycin; systemic
1.7
10.2
221
1438
M05BA07
ATC
risedronic acid; oral
3.8
10.2
31
84
X58
ICD-10 Finland
Exposure to other specified factors
2.0
10.2
129
712
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
13.3
10.2
17
13
ZXE00
NOMESCO Finland
One hour or less
1.6
10.2
310
2206
J01DA09
ATC
[U] cefadroxil
1.7
10.1
229
1508
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
10.0
90
438
7177A
ICD-9 Finland
Internal derangement of knee, Chondromalacia of patella
7.8
9.9
22
29
SPAT1216
SPAT
Assessment of functional ability
2.0
9.9
120
653
SPAT1059
SPAT
Spirometry at the office
2.8
9.9
51
192
-1, ,
NOMESCO Finland
1.6
9.8
272
1885
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.3
9.8
36
111
Z3226
NOMESCO Finland
Physiotherapist
1.9
9.8
141
812
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
9.7
100
512
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
9.7
189
1192
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
9.7
208
1348
NDL52
NOMESCO Finland
Tenosynovectomy of hand
13.6
9.7
16
12
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.8
9.6
49
183
A02BC03
ATC
lansoprazole; oral
1.7
9.6
236
1586
R52.9
ICD-10 Finland
Pain, unspecified
2.1
9.5
90
446
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
101.1
9.4
10
*
NHG20
NOMESCO Finland
Fusion of talocrural joint
17.8
9.4
14
8
J01MA02
ATC
ciprofloxacin; systemic
1.6
9.4
306
2203
212
Kela drug reimbursment
Gout
+∞
9.4
9
*
NGC20
NOMESCO Finland
Secondary implantation of prosthesis in knee joint, normal prosthesis
+∞
9.4
9
*
9522
FHL
Synovectomy
+∞
9.4
9
*
291
Kela drug reimbursment
Tofacitinib
+∞
9.4
9
*
NG1EA
NOMESCO Finland
Knee X-ray examination with wrench
12.5
9.4
16
13
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.8
9.4
48
180
H02BX01
ATC
methylprednisolone, combinations; systemic
3.0
9.3
40
136
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
9.3
149
887
L11
ICPC
Wrist symptom/complaint
2.1
9.3
87
430
A01
ICPC
Pain general/multiple sites
2.2
9.2
82
397
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
9.2
122
684
M01AB01
ATC
indometacin; systemic, rectal
2.5
9.1
57
236
ACC51
NOMESCO Finland
Release of median nerve
2.3
9.0
68
307
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
7.6
9.0
20
27
TQW40, ,
SPAT
2.1
9.0
86
429
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
9.0
201
1316
Z02.7
ICD-10 Finland
Issue of medical certificate
2.3
8.9
65
289
ZSN00
NOMESCO Finland
Procedure related to previous procedure classified in chapter N
24.3
8.9
12
5
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
8.9
152
922
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
8.8
189
1221
SPAT1263
SPAT
Sampling
1.6
8.8
325
2401
R05
ICPC
Cough
1.7
8.8
209
1388
WX204
NOMESCO Finland
Axillary plexus blockaced
3.2
8.8
35
114
R03AC02
ATC
salbutamol; inhalant
1.5
8.7
453
3606
WZA10
NOMESCO Finland
Extensive medical or dental certificate
7.7
8.7
19
25
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
3.8
8.7
26
70
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
4.6
8.6
20
44
G47.3
ICD-10 Finland
Sleep apnoea
1.7
8.6
186
1204
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
8.6
411
3209
M25.0
ICD-10 Finland
Haemarthrosis
16.5
8.6
13
8
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
9.1
8.6
17
19
UJF32
NOMESCO Finland
Coloscopy
1.7
8.6
206
1372
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.9
8.5
118
670
ZX120
NOMESCO Finland
Intravenous
2.1
8.5
78
383
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
2.6
8.5
50
202
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
3.4
8.4
30
91
M01AC01
ATC
piroxicam; systemic, rectal
1.9
8.4
105
577
TNC11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in elbow joint
+∞
8.3
8
*
NDF60
NOMESCO Finland
Operation for osteochondritis of a joint of hand,v
+∞
8.3
8
*
R06AE07
ATC
cetirizine; oral
1.5
8.3
358
2727
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
8.3
103
564
J01DA01
ATC
[U] cefalexin
1.5
8.3
503
4121
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
4.3
8.2
21
50
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
4.3
8.2
21
50
WX002
NOMESCO Finland
Sedation and analgesia
1.8
8.2
133
793
J01FA09
ATC
clarithromycin; systemic
1.6
8.2
256
1816
L01
ICPC
Neck symptom/complaint
1.8
8.1
136
819
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
33.7
8.1
10
*
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
17.4
8.1
12
7
NG1AA, ,
SPAT
2.2
7.9
69
331
J01CA04
ATC
amoxicillin; systemic
1.6
7.9
680
5979
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
4.5
7.9
19
43
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.6
7.9
203
1371
NE1BA
NOMESCO Finland
Pelvis extensive X-ray examination
13.2
7.9
13
10
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
7.9
116
672
Z01.2
ICD-10 Finland
Dental examination
1.5
7.8
369
2856
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
7.8
64
300
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
7.0
7.8
18
26
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
7.8
182
1200
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
7.8
298
2206
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
3.9
7.7
22
57
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
7.7
590
5036
1XC02, ,
NOMESCO Finland
15.2
7.7
12
8
NCF20
NOMESCO Finland
Operation for osteochondritis of elbow joint, open
45.4
7.7
9
*
M17.4
ICD-10 Finland
Other secondary gonarthrosis, bilateral
45.4
7.7
9
*
SPAT1104
SPAT
Monitoring of emergency patient
2.4
7.7
52
224
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
7.7
158
1007
R03DC03
ATC
montelukast; oral
1.7
7.7
141
871
J01MA01
ATC
ofloxacin; systemic
2.1
7.6
74
371
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
18.5
7.6
11
6
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
25.2
7.6
10
*
NGE15
NOMESCO Finland
Incision fo capsule of knee joint, arthroscopic
25.2
7.6
10
*
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
6.2
7.6
19
31
L04AD01
ATC
ciclosporin; systemic
6.2
7.6
19
31
P01AB01
ATC
metronidazole; oral, rectal
1.5
7.5
336
2567
SPAT1211
SPAT
Application of soft bandage
2.2
7.5
65
312
L29
ICPC
Musculoskeletal sympt/complt other
2.1
7.5
70
346
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
7.5
86
459
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
7.4
246
1761
R01AD09
ATC
mometasone; nasal
1.5
7.4
368
2871
R5110, ,
SPAT
2.2
7.4
64
307
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.5
7.4
46
191
A02BC01
ATC
omeprazole; systemic
1.6
7.4
205
1410
NH1AD
NOMESCO Finland
Ankle and foot CT
3.7
7.3
23
64
R42
ICD-10 Finland
Dizziness and giddiness
1.6
7.3
181
1209
S76
ICPC
Skin infection other
2.5
7.3
47
198
3006
Kela drug reimbursment
Baricitinib
+∞
7.3
7
*
7190F
ICD-9 Finland
Other and unspecified disorder of joint, Effusion of joint[HYDROPS (HYDRARTHRON), POLVI]
+∞
7.3
7
*
NGC30
NOMESCO Finland
Secondary implantation of prosthesis in knee joint, special prosthesis
+∞
7.3
7
*
9256
FHL
Synovectomy (knee 9311)
+∞
7.3
7
*
L01CB
ATC
Podophyllotoxin derivatives
+∞
7.3
7
*
293
Kela drug reimbursment
Baricitinib
+∞
7.3
7
*
71250
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Chronic rheumatoid nodular fibrositis
+∞
7.3
7
*
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
9.5
7.3
14
15
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
3.4
7.3
26
79
P01BA01
ATC
chloroquine; systemic
15.9
7.2
11
7
TND10
NOMESCO Finland
Joint puncture, wrist or finger joint
30.3
7.2
9
*
R51.80
ICD-10 Finland
Headache
1.7
7.1
130
801
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.2
7.1
62
298
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.8
7.1
21
56
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.3
7.1
51
226
NF1DA
NOMESCO Finland
X-ray of hips
12.1
7.1
12
10
9254
FHL
Arthrotomy (includes biopsy, revision, loose removal, fixation, and similar procedures)
12.1
7.1
12
10
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.7
7.1
36
135
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.7
7.1
22
61
1223
FHL
Arthroscopy and articular cartilage surgery
10.1
7.0
13
13
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.5
7.0
44
183
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.0
7.0
80
425
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
7.0
80
425
M75
ICD-10 Finland
Shoulder lesions
2.5
7.0
42
171
K07.60
ICD-10 Finland
Snapping jaw
2.4
7.0
46
196
J01FA06
ATC
roxithromycin; oral
1.5
7.0
314
2393
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
7.0
421
3398
R4110, ,
SPAT
1.8
6.9
99
568
J01MA12
ATC
levofloxacin; systemic
1.7
6.9
140
888
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
3.4
6.9
24
72
SPAT1210
SPAT
Application of cast or individual aid
2.6
6.9
38
149
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
11.0
6.8
12
11
R60.0
ICD-10 Finland
Localized oedema
1.9
6.8
87
482
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
40.4
6.8
8
*
NGT60
NOMESCO Finland
Forcible manipulation of knee joint
40.4
6.8
8
*
Z3231
NOMESCO Finland
Registered nurse
1.6
6.8
208
1461
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
6.8
140
893
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
3.0
6.7
29
99
XA402
NOMESCO Finland
ENMG
3.6
6.7
22
63
L08
ICPC
Shoulder symptom/complaint
1.6
6.7
178
1207
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
22.7
6.7
9
*
NK4EA
NOMESCO Finland
Joint X-ray examintion with load or wrench not elsewhere classified
22.7
6.7
9
*
R52.2
ICD-10 Finland
Other chronic pain
2.8
6.7
33
122
R50.9
ICD-10 Finland
Fever, unspecified
1.7
6.6
116
706
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.3
6.6
48
214
M87.0
ICD-10 Finland
Idiopathic aseptic necrosis of bone
12.4
6.6
11
9
B01AX05
ATC
fondaparinux; parenteral
12.4
6.6
11
9
M01AE52
ATC
naproxen and esomeprazole; oral
3.0
6.6
28
95
S83.2
ICD-10 Finland
Tear of meniscus, current
2.3
6.6
46
202
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.8
6.5
31
112
A99
ICPC
Disease/condition unspecnature/site
1.9
6.5
85
473
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.6
6.5
160
1065
Z71.9
ICD-10 Finland
Counselling, unspecified
2.0
6.5
72
379
J02AC01
ATC
fluconazole; systemic
1.5
6.5
320
2475
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.6
6.5
184
1268
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.1
6.5
59
289
M70.6
ICD-10 Finland
Trochanteric bursitis
1.8
6.5
99
580
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.0
6.4
68
352
L16
ICPC
Ankle symptom/complaint
1.8
6.4
93
535
C08CA01
ATC
amlodipine; oral
1.5
6.4
285
2159
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.4
6.4
43
185
ZXD20
NOMESCO Finland
Day surgery
1.8
6.4
99
581
Z71.8
ICD-10 Finland
Other specified counselling
1.5
6.4
268
2006
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.1
6.4
62
311
H02AB09
ATC
hydrocortisone; systemic
3.5
6.3
21
61
NGE10
NOMESCO Finland
Incision or suture of capsule of knee joint
11.1
6.3
11
10
ND2BG
NOMESCO Finland
MRI of hand
11.1
6.3
11
10
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
6.3
140
909
B01AX06
ATC
[U] rivaroxaban
18.2
6.3
9
5
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
18.2
6.3
9
5
NGU00
NOMESCO Finland
Removal of partial prosthesis from knee joint, other or unspecified
+∞
6.3
6
*
7140B
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SERONEGATIVA]
+∞
6.3
6
*
L04AA37
ATC
[U] baricitinib
+∞
6.3
6
*
NGC60
NOMESCO Finland
Exchange or addition of patellar part
+∞
6.3
6
*
NGB10
NOMESCO Finland
Primary partial prosthetic replacement of knee joint, demi prosthesis
+∞
6.3
6
*
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
6.3
6
*
NH3AE
NOMESCO Finland
Feet ultrasound examination
+∞
6.3
6
*
M16.7
ICD-10 Finland
Other secondary coxarthrosis
+∞
6.3
6
*
R01AD08
ATC
fluticasone; nasal
1.5
6.2
226
1641
M03BC01
ATC
orphenadrine (citrate); systemic
1.6
6.2
174
1193
WZC30
NOMESCO Finland
Teaching
1.7
6.2
129
822
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
6.2
138
895
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
3.7
6.2
19
52
M19.9
ICD-10 Finland
Arthrosis, unspecified
2.7
6.2
33
127
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.2
221
1600
M15
ICD-10 Finland
Polyarthrosis
2.6
6.2
35
139
R02
ICPC
Shortness of breath/dyspnoea
1.8
6.2
102
611
R05FB02
ATC
cough suppressants and expectorants; systemic
1.5
6.1
285
2174
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
6.1
83
468
ZXA10
NOMESCO Finland
Bilateral
1.7
6.1
131
842
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
6.1
139
907
Z00.0
ICD-10 Finland
General medical examination
1.6
6.1
147
973
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
6.1
466
3893
S80.0
ICD-10 Finland
Contusion of knee
2.1
6.1
60
303
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
6.1
233
1712
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
6.1
759
6982
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
6.8
6.0
14
21
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.3
6.0
22
68
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
6.0
157
1059
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
3.9
6.0
17
44
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
6.0
106
647

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
114
43
30.34
169.06
1.9
1.1
15128.47
17049.81
e6/l
0.09
86
31
119
56
24.45
162.49
1.7
1.0
—
—
—
0
0
365
1044
5.29
123.62
1.7
1.2
52.43
2.92
u/ml
12.50
180
397
62
14
47.59
105.29
1.5
1.0
52.87
83.40
%
—
38
5
355
1164
4.45
97.65
1.6
1.2
72.43
17.97
iu/ml
6.62
186
316
68
33
22.26
90.82
1.7
1.1
—
—
—
0
0
269
827
4.26
78.54
1.6
1.2
441.62
358.06
titre
0.43
74
144
608
3572
3.31
58.92
10.7
5.1
0.04
0.04
e9/l
0.53
569
3041
108
196
6.15
58.24
1.8
1.3
6.32
4.43
iu/ml
0.42
31
43
615
3697
3.25
56.05
10.8
5.4
0.19
0.19
e9/l
0.06
576
3209
601
3568
3.20
55.94
10.7
5.1
0.58
0.57
e9/l
1.05
562
3038
40
17
24.61
55.91
1.6
1.1
173761.86
42504.25
e6/l
0.55
28
12
565
3270
3.06
54.45
11.2
5.2
0.75
0.68
%
2.34
551
3054
565
3275
3.06
54.20
11.0
5.2
2.85
2.88
%
0.11
550
3062
606
3655
3.15
54.04
10.8
5.1
1.85
1.98
e9/l
1.05
570
3185
568
3306
3.06
54.00
10.9
5.1
57.22
56.93
%
0.27
558
3164
563
3282
3.01
52.97
11.3
5.2
8.88
8.74
%
0.60
551
3070
566
3380
2.92
49.60
11.1
5.2
27.96
28.07
%
0.10
557
3208
633
4111
2.96
45.58
14.1
9.2
3.95
4.06
e9/l
0.73
583
3538
336
1655
2.67
40.97
3.1
2.4
338.36
333.94
umol/l
0.36
308
1472
205
796
3.06
38.97
3.9
3.3
3.99
5.53
e9/l
1.20
181
702
405
2292
2.43
35.59
10.0
5.1
—
—
—
0
0
152
581
2.96
29.10
5.3
4.1
0.90
1.00
%
0.14
52
184
147
552
3.00
29.05
5.3
4.2
0.10
0.12
%
0.10
48
156
144
554
2.92
27.15
4.8
4.1
0.37
0.69
%
1.72
46
170
140
555
2.81
24.86
5.7
4.5
0.03
0.14
%
0.94
37
135
128
490
2.89
24.23
3.8
2.9
10.16
10.85
g/l
0.86
117
452
39
61
6.65
24.08
1.5
1.2
—
—
—
0
0
61
148
4.36
23.24
1.3
1.2
2.56
3.61
u/ml
—
5
16
710
5611
2.42
23.23
11.4
7.7
75.24
79.34
u/l
2.47
695
5314
61
149
4.33
23.04
1.3
1.1
4.63
2.58
u/ml
—
6
9
152
656
2.59
22.73
4.0
4.2
7.38
7.36
ph
1.55
126
472
283
1605
2.13
22.39
7.0
4.0
—
—
—
0
0
443
2980
1.99
21.66
3.9
3.1
6.11
6.20
ph
0.91
249
1707
524
3742
2.00
21.49
4.8
3.4
13.60
8.33
estimate
0.15
106
761
88
295
3.21
20.91
2.1
2.1
0.00
0.01
estimate
0.49
26
90
513
3700
1.94
19.70
4.8
3.4
0.00
0.00
estimate
0.50
102
755
467
3299
1.89
18.75
2.9
2.3
77.99
77.33
nmol/l
0.18
439
2964
514
3761
1.89
18.32
4.9
3.5
0.00
0.02
estimate
1.46
101
716
174
890
2.19
17.41
2.0
1.9
—
—
—
0
0
131
614
2.33
16.09
2.3
2.0
0.04
0.04
estimate
0.02
26
123
112
492
2.46
15.89
1.4
1.5
—
—
—
0
0
60
194
3.25
15.10
1.1
1.1
—
—
—
0
0
143
735
2.13
13.93
1.4
1.6
—
—
—
0
0
475
3581
1.72
13.53
7.2
7.3
1.22
1.21
mmol/l
0.54
426
3078
95
426
2.38
12.82
4.4
3.2
5.21
5.15
kpa
0.27
89
414
806
7206
2.54
12.75
23.7
13.4
18.24
25.14
mg/l
11.17
734
5739
423
3127
1.68
12.66
13.4
12.6
1.24
1.22
inr
0.21
356
2599
93
417
2.38
12.55
3.8
3.2
7.42
7.42
ph
0.09
83
352
236
1489
1.80
12.46
1.6
1.5
2.50
2.41
g/l
0.18
146
916
175
1010
1.92
12.24
1.4
1.6
—
—
—
0
0
19
12
16.15
12.18
2.4
1.2
—
—
—
0
0
89
399
2.37
12.01
2.0
1.8
1.31
1.37
g/l
0.11
79
369
310
2142
1.69
11.74
2.2
2.0
155.58
260.60
u/l
1.31
298
2042
416
3119
1.64
11.37
2.9
2.6
—
—
estimate
—
0
0
33
91
3.73
10.60
3.2
2.9
4.01
4.15
e9/l
0.14
33
91
336
2421
1.63
10.56
3.8
3.3
—
0.78
—
0
9
317
2252
1.64
10.54
2.5
2.3
—
—
—
0
0
93
449
2.20
10.53
2.2
2.4
39.08
23.52
au/ml
—
6
47
282
1961
1.65
10.12
3.3
3.0
1112.86
1164.94
ng/l
0.12
245
1663
518
4190
1.58
9.68
4.6
5.2
6.54
6.68
mmol/l
0.92
496
3985
98
502
2.07
9.53
2.1
3.5
65.69
66.68
g/l
0.68
92
461
82
392
2.21
9.51
2.1
3.1
—
—
—
0
0
179
1123
1.75
9.35
2.6
2.4
12.43
13.86
umol/l
2.06
172
1043
410
3168
1.55
9.20
16.7
9.6
0.00
0.00
e9/l
1.34
348
2533
103
545
2.01
9.16
2.4
2.1
0.15
0.72
e6/l
2.21
96
519
344
2570
1.56
8.89
4.6
3.4
89.04
112.37
e6/l
0.13
249
1768
241
1668
1.61
8.59
2.6
2.3
—
—
—
0
0
66
301
2.29
8.57
3.7
3.3
—
—
—
0
0
167
1053
1.72
8.51
2.5
2.4
2.34
2.34
g/l
0.08
159
976
221
1509
1.62
8.28
3.3
2.4
4.56
6.68
e6/l
1.76
207
1369
153
955
1.73
8.06
2.6
2.5
21.09
23.74
%
1.99
147
894
97
526
1.95
8.04
2.4
2.5
5.99
6.12
ph
0.84
65
346
404
3182
1.50
7.89
6.0
6.6
1.22
1.21
mmol/l
1.16
379
2928
35
124
2.90
7.61
3.1
2.9
57.66
56.93
%
0.11
35
124
226
1581
1.58
7.57
1.7
1.6
1.19
1.16
mg/l
0.06
177
1217
23
64
3.66
7.34
2.7
4.3
—
—
—
0
0
37
138
2.76
7.33
1.2
1.2
—
—
—
0
0
384
3025
1.48
7.32
2.4
2.1
—
—
—
0
0
21
56
3.82
7.11
1.2
1.1
—
—
—
0
0
397
3167
1.47
7.00
5.2
5.0
35.24
36.10
g/l
2.14
378
2976
256
1875
1.52
6.88
4.5
4.1
—
—
—
0
0
275
2047
1.50
6.83
5.4
3.4
0.00
0.00
estimate
1.08
98
702
111
665
1.77
6.71
2.0
2.1
322.42
392.97
nmol/l
3.54
103
625
362
2856
1.46
6.67
4.8
3.4
0.26
0.08
estimate
0.31
95
605
117
716
1.73
6.57
2.8
2.6
1.69
1.82
%
1.03
104
641
51
235
2.24
6.51
3.3
3.4
407.65
521.04
mg/l
0.16
17
103
239
1759
1.49
6.18
2.6
2.1
3.03
2.81
mg/l
0.85
215
1477
141
923
1.63
6.13
2.3
2.4
135.82
109.89
ug/g
0.51
117
738
465
3905
1.41
5.78
6.7
6.9
10.19
11.42
umol/l
0.98
442
3735
291
2250
1.44
5.77
4.0
2.9
23.49
58.43
e6/l
2.68
241
1679
100
612
1.72
5.61
1.1
1.2
—
—
—
0
0
269
2065
1.44
5.50
4.1
3.0
0.53
0.02
estimate
0.47
94
588
90
546
1.72
5.21
2.1
2.8
67.90
72.13
e9/l
0.71
80
400
146
1001
1.55
5.19
1.3
1.3
—
—
—
0
0
31
127
2.49
5.17
3.0
5.2
—
—
—
0
0
31
127
2.49
5.17
4.4
2.3
90.63
90.10
%
0.16
31
122
383
3161
1.38
5.04
2.2
2.0
94.04
96.14
pmol/l
0.40
231
1677
296
2347
1.40
4.94
2.9
2.6
57.43
62.73
u/l
0.79
283
2174
230
1745
1.43
4.94
1.3
1.3
0.63
1.53
u/ml
2.25
53
471
748
6931
1.55
4.93
6.3
5.9
38.42
39.08
mmol/mol
1.43
720
6471
9
10
9.08
4.79
1.0
1.1
—
—
—
0
0
171
1233
1.48
4.78
1.6
1.9
—
—
—
0
0
318
2566
1.38
4.74
3.0
3.7
2.35
2.36
mmol/l
1.57
295
2344
793
7464
1.68
4.73
21.1
16.5
139.72
139.75
mmol/l
0.13
780
7295
794
7476
1.69
4.73
21.4
16.6
3.97
3.96
mmol/l
0.75
780
7289
19
64
3.01
4.58
1.9
4.1
55.39
56.60
%
0.08
19
58
41
201
2.09
4.55
2.5
4.5
28.91
63.47
mg/l
1.13
34
180
41
201
2.09
4.55
2.5
4.5
42.80
47.34
mg/l
0.20
35
178
128
878
1.54
4.53
1.3
1.5
—
—
—
0
0
139
974
1.51
4.46
1.3
1.2
—
—
—
0
0
42
212
2.03
4.33
1.3
1.5
344.48
278.22
ug/g
1.00
23
127
20
73
2.78
4.20
1.6
1.8
—
—
—
0
0
26
109
2.43
4.18
1.4
1.3
28.29
25.74
u/l
0.12
20
89
116
793
1.53
4.17
1.7
1.6
—
—
—
0
0
9
13
6.98
4.17
1.0
1.0
—
—
—
0
0
9
13
6.98
4.17
1.0
1.0
—
—
—
0
0
9
13
6.98
4.17
1.0
1.0
—
—
—
0
0
50
274
1.87
4.09
1.6
1.7
1.41
1.48
g/l
0.22
44
240
328
2714
1.33
4.00
4.0
3.3
21.85
53.37
ng/l
1.58
242
1838
406
3466
1.32
3.97
3.3
2.9
108.04
123.90
ug/l
1.15
392
3245
11
23
4.83
3.88
1.2
1.3
156.45
169.81
mmol/24h
0.18
11
23
36
180
2.04
3.84
2.2
4.4
4.56
4.60
ratio
0.00
26
103
243
1934
1.36
3.81
3.8
2.8
0.24
0.54
e6/l
2.95
191
1378
284
2323
1.33
3.69
3.4
3.3
83.34
47.60
mg/l
0.91
192
1455
21
85
2.51
3.65
1.7
1.4
42.90
46.64
mu/l
0.06
21
78
150
1110
1.42
3.62
1.8
1.6
954.18
1190.39
nmol/l
3.11
119
844
14
40
3.54
3.61
1.1
1.1
—
—
—
0
0
732
6852
1.42
3.60
6.0
5.2
1.83
1.91
mu/l
1.14
700
6357
287
2358
1.32
3.60
4.0
3.9
19.13
8.50
mg/mmol
1.03
188
1453
54
317
1.75
3.57
1.3
1.2
—
—
—
0
0
817
7826
1.69
3.57
28.3
17.7
75.32
75.25
umol/l
0.03
812
7725
13
38
3.46
3.32
1.1
1.1
—
—
—
0
0
38
205
1.89
3.30
1.5
1.1
—
—
—
0
0
812
7785
1.62
3.29
20.2
10.5
25.59
26.02
u/l
0.44
803
7561
246
2003
1.32
3.24
1.9
1.6
18.36
20.27
nmol/l
1.52
215
1696
296
2474
1.30
3.21
3.5
3.2
7.33
7.67
mmol/l
0.62
267
2138
261
2149
1.31
3.16
10.1
5.8
—
—
—
0
0
13
44
2.98
3.14
1.2
1.4
68.69
79.36
umol/l
0.68
13
44
12
35
3.46
3.11
1.8
4.0
15.80
17.09
%
0.90
12
35
118
861
1.43
3.08
1.4
1.3
—
—
—
0
0
54
333
1.66
3.02
2.2
2.3
—
—
—
0
0
12
36
3.37
3.02
1.6
3.6
7.12
9.53
mmol/l
1.26
12
36
16
63
2.57
2.97
2.6
2.0
1.27
0.79
mmol/l
0.13
16
63
12
38
3.19
2.86
1.5
2.1
106.67
114.98
ng/l
0.08
12
38
517
4671
1.26
2.85
5.5
4.1
516.13
2655.28
e6/l
—
8
60
205
1668
1.30
2.66
5.2
3.4
1.02
1.96
kg/l
0.50
158
1070
49
307
1.63
2.61
2.4
1.8
—
—
—
0
0
563
5180
1.24
2.46
3.8
3.2
49.81
48.46
u/l
0.15
535
4906
17
77
2.23
2.38
1.5
1.7
40.39
25.20
ng/l
0.30
17
77
121
930
1.35
2.34
5.2
5.4
1.06
1.02
mmol/l
1.03
116
844
625
5834
1.25
2.32
5.0
4.3
14.83
14.68
pmol/l
0.82
597
5382
5
9
5.58
2.21
1.2
1.2
—
—
—
0
0
65
453
1.47
2.21
3.0
3.5
4.24
4.59
pmol/l
2.14
56
407
733
6992
1.30
2.17
4.6
4.1
1.37
1.28
mmol/l
2.37
698
6465
147
1181
1.29
2.09
3.4
2.6
0.79
1.14
e6/l
0.99
84
588
8
26
3.10
2.01
1.1
1.0
261.02
268.58
iu/ml
—
8
26
151
1224
1.28
2.01
3.1
3.4
0.80
0.82
mmol/l
1.52
143
1161
245
2102
1.23
2.00
4.1
4.0
7.40
7.40
ph
0.20
195
1470
23
127
1.83
1.95
1.9
1.9
—
—
—
0
0
66
475
1.42
1.92
2.6
2.9
166.41
190.69
ng/l
0.18
58
437
163
1346
1.26
1.87
3.3
2.7
526.26
527.04
mosm/kgh2o
0.02
149
1173
25
145
1.75
1.83
3.1
1.9
129.85
129.49
g/l
0.03
20
117
743
7137
1.28
1.81
5.2
4.8
5.89
5.89
mmol/l
0.03
702
6578
5
13
3.86
1.71
1.0
1.2
—
—
—
0
0
12
55
2.20
1.68
1.2
1.4
9.27
11.45
umol/l
1.68
12
50
51
362
1.43
1.63
1.2
1.2
—
—
—
0
0
278
3120
0.84
1.62
3.0
3.1
—
—
—
0
0
5
14
3.59
1.61
1.0
1.9
—
—
—
0
0
7
26
2.71
1.58
1.0
1.7
29.86
31.85
%
—
7
26
163
1373
1.23
1.57
3.6
3.7
173.02
337.06
ng/l
0.65
116
1024
71
539
1.35
1.54
3.9
3.4
1.22
1.23
mmol/l
0.63
66
449
35
236
1.50
1.46
2.2
2.5
—
—
—
0
0
771
7477
1.27
1.46
5.9
5.5
2.75
2.77
mmol/l
0.26
742
6987
822
8041
1.38
1.45
34.3
20.8
262.75
253.38
e9/l
3.76
814
7858
12
59
2.05
1.44
1.1
1.3
153598.57
41404.76
e6/l
—
7
33
6
22
2.74
1.43
1.8
1.6
—
—
—
0
0
71
547
1.32
1.42
2.4
3.7
78.88
86.07
ng/l
0.38
60
475
822
8045
1.37
1.40
34.3
20.8
4.47
4.51
e12/l
1.68
813
7838
822
8045
1.37
1.40
34.3
20.8
6.91
6.62
e9/l
3.67
810
7837
171
1466
1.21
1.39
1.6
1.7
452.47
39411715.28
pmol/l
1.92
145
1223
761
7377
1.25
1.39
5.4
4.9
4.68
4.72
mmol/l
0.51
734
6919
758
7345
1.24
1.38
5.3
4.8
1.45
1.49
mmol/l
1.75
728
6842
18
105
1.73
1.34
1.1
1.2
3.00
6.36
u/ml
—
6
42
170
1463
1.20
1.33
2.8
3.0
2.44
2.45
mmol/l
0.22
159
1329
9
43
2.10
1.30
1.9
1.8
5.84
9.56
ug/l
—
9
38
8
36
2.23
1.24
1.0
1.2
789.63
619.65
u/l
—
8
31
586
6135
0.86
1.24
25.4
17.2
13.71
13.56
%
2.57
581
6036
12
63
1.92
1.23
1.2
1.1
—
—
—
0
0
239
2138
1.16
1.19
3.6
2.9
—
—
—
0
0
205
1815
1.17
1.16
3.6
3.8
93.90
91.54
%
0.66
199
1779
29
199
1.47
1.16
2.3
3.1
0.29
2.52
index
4.17
14
109
5
20
2.51
1.15
1.0
1.5
—
—
—
0
0
11
58
1.91
1.12
1.2
1.1
—
—
—
0
0
13
74
1.77
1.07
9.8
7.0
13.51
11.65
mg/l
0.92
13
69
279
2545
1.14
1.05
3.2
3.2
35.78
32.79
u/l
0.25
270
2412
103
867
1.21
1.04
2.3
2.7
7.58
8.12
umol/l
0.08
91
771
18
114
1.59
1.03
1.1
1.1
—
—
—
0
0
45
343
1.33
1.02
1.1
1.1
—
86.57
—
0
7
9
48
1.88
1.00
1.1
1.1
53.73
32.75
mg/l
—
9
39
7
35
2.01
1.00
2.3
1.4
1.46
1.26
nmol/l
—
7
25
5
23
2.18
0.98
1.6
1.8
68.20
1291.26
nmol/24h
—
5
23
0
30
0.00
0.97
0.0
1.8
—
—
—
0
0
219
1975
1.15
0.97
5.1
5.0
2.00
2.49
ug/l
0.95
206
1780
9
50
1.81
0.97
1.6
3.1
2144.33
774.40
mg
—
9
50
50
633
0.78
0.96
1.4
1.8
—
—
—
0
0
80
664
1.23
0.94
1.5
1.4
—
—
—
0
0
12
196
0.61
0.93
1.5
2.8
64.87
60.24
%
0.35
12
191
773
7561
1.20
0.92
17.8
12.4
—
—
—
0
0
10
55
1.83
0.92
1.1
1.2
—
—
—
0
0
18
118
1.54
0.91
1.2
1.1
—
—
—
0
0
16
102
1.58
0.91
1.2
1.4
—
0.74
nmol/l
—
0
7
67
549
1.24
0.89
2.3
2.3
3.88
7.63
ug/l
2.66
62
494
10
56
1.79
0.88
1.3
1.1
—
—
—
0
0
14
88
1.60
0.84
1.2
1.4
—
—
—
0
0
28
205
1.38
0.84
1.3
1.4
7.45
10.77
u/l
0.63
17
166
28
205
1.38
0.84
1.1
1.1
3.06
7.99
eliau/ml
—
5
26
10
57
1.76
0.84
1.1
1.3
—
—
—
0
0
92
786
1.19
0.82
1.2
1.4
—
—
—
0
0
68
814
0.82
0.82
1.4
1.7
—
—
—
0
0
6
32
1.88
0.82
1.0
1.3
5.48
6.49
mmol/l
—
6
32
12
73
1.65
0.82
2.4
3.2
32.08
32.16
pg
0.02
12
73
6
33
1.82
0.79
2.5
4.0
424.17
1297.15
u/ml
—
6
33
6
33
1.82
0.79
1.2
1.2
140.00
149.22
nmol/l
—
6
33
8
48
1.67
0.79
1.0
1.1
199.13
224.12
mg/l
—
8
41
19
131
1.46
0.79
4.8
3.1
—
—
—
0
0
15
98
1.54
0.78
1.2
1.4
0.46
0.59
nmol/l
1.07
15
93
7
123
0.57
0.78
3.7
5.6
282.86
371.08
umol/l
—
7
112
45
558
0.80
0.76
1.2
1.2
146.90
126.34
u/ml
0.07
12
221
6
34
1.77
0.76
1.0
1.0
—
—
—
0
0
5
25
2.01
0.72
3.8
2.4
—
—
—
0
0
14
92
1.53
0.72
1.7
1.4
—
—
—
0
0
14
92
1.53
0.72
1.7
1.4
—
—
—
0
0
14
92
1.53
0.72
1.7
1.4
—
—
—
0
0
14
92
1.53
0.72
1.7
1.4
—
—
—
0
0
9
56
1.61
0.72
2.6
1.9
18.28
20.08
nmol/l
—
9
51
17
117
1.46
0.72
3.9
2.1
—
—
—
0
0
11
68
1.63
0.72
1.9
2.5
—
—
—
0
0
40
320
1.26
0.69
3.4
3.2
24.96
25.31
mmol/l
0.31
40
309
10
61
1.65
0.68
1.3
1.1
113.90
111.25
pmol/l
—
10
61
9
59
1.53
0.68
1.1
1.2
—
—
—
0
0
89
774
1.17
0.67
6.6
9.9
0.86
0.87
mmol/l
0.00
71
637
10
62
1.62
0.65
3.6
2.7
—
—
—
0
0
498
5170
0.91
0.65
4.1
3.7
—
7770.77
—
0
13
57
675
0.83
0.65
1.7
1.8
3.48
3.50
mmol/l
0.06
39
481
20
269
0.74
0.64
1.3
1.5
1068.66
987.85
mu/l
0.17
14
222
35
280
1.26
0.62
1.6
1.7
7.28
9.67
u/ml
—
6
70
0
20
0.00
0.60
0.0
1.2
—
23.35
—
0
15
91
802
1.15
0.59
3.0
4.7
3.06
26.06
ug/l
1.54
67
663
7
114
0.61
0.58
3.1
2.4
—
—
—
0
0
50
421
1.20
0.57
1.5
1.4
21.24
30.32
iu/l
1.48
44
364
11
74
1.49
0.53
2.0
2.4
—
—
—
0
0
9
62
1.46
0.53
1.1
1.0
—
—
—
0
0
6
39
1.54
0.53
1.3
2.2
—
—
—
0
0
38
314
1.22
0.52
1.3
1.6
0.28
0.34
mg/l
0.36
15
148
9
136
0.66
0.51
1.2
1.5
—
—
—
0
0
6
40
1.50
0.51
1.0
1.1
0.60
0.49
ratio
—
6
21
9
65
1.39
0.50
1.0
1.1
319.11
293.68
mg/l
—
9
57
11
76
1.45
0.48
1.4
1.2
—
—
—
0
0
14
102
1.38
0.47
1.1
1.0
0.22
0.44
u/ml
—
6
33
20
155
1.30
0.47
2.6
2.3
41.29
119.32
ug/min
1.29
13
94
13
94
1.39
0.46
3.3
2.7
—
—
—
0
0
11
77
1.43
0.45
1.0
1.1
—
—
—
0
0
34
405
0.83
0.45
2.1
3.5
24.08
24.15
mmol/l
0.04
34
399
87
783
1.12
0.44
6.7
9.9
7.41
7.41
ph
0.21
53
426
7
51
1.38
0.44
1.1
1.2
—
—
—
0
0
9
129
0.69
0.43
1.2
1.2
—
—
—
0
0
9
131
0.68
0.43
1.2
1.5
—
—
—
0
0
62
548
1.14
0.42
5.0
3.5
—
—
—
0
0
12
87
1.38
0.42
1.2
1.7
—
—
—
0
0
39
455
0.85
0.41
1.6
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
15
114
1.32
0.41
2.9
3.7
0.76
0.78
nmol/l
—
10
93
0
17
0.00
0.40
0.0
1.2
—
0.67
—
0
11
0
17
0.00
0.40
0.0
3.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
5
34
1.47
0.40
4.2
1.5
—
—
—
0
0
121
1118
1.10
0.39
3.5
2.6
3.72
2.89
e6/l
0.34
58
519
5
37
1.35
0.37
1.0
1.1
18.60
9.14
mm/h
—
5
37
5
77
0.65
0.36
1.0
1.8
13.68
10.62
%
—
5
77
15
117
1.29
0.35
1.1
1.1
14.57
2.59
u/ml
—
6
55
20
163
1.23
0.34
1.7
1.7
—
—
—
0
0
28
237
1.19
0.34
1.6
2.2
593.28
4997.05
u/l
—
10
95
14
109
1.29
0.33
1.4
1.2
—
—
—
0
0
17
137
1.25
0.32
1.1
1.1
1.92
4.25
u/ml
—
9
66
77
707
1.10
0.30
2.3
2.4
41.20
37.75
u/l
0.14
65
599
12
93
1.29
0.30
2.2
2.1
—
—
—
0
0
31
269
1.16
0.29
1.4
1.3
273.52
238.60
miu/ml
0.19
19
132
20
238
0.84
0.29
10.3
10.4
—
—
—
0
0
7
57
1.23
0.29
1.6
1.3
—
—
—
0
0
20
167
1.20
0.28
1.7
3.2
27.45
33.91
umol/l
0.90
20
154
25
214
1.17
0.28
1.1
1.2
—
—
—
0
0
8
64
1.25
0.27
1.1
1.5
—
—
—
0
0
44
397
1.11
0.25
4.1
6.4
—
—
—
0
0
23
198
1.17
0.25
1.4
1.2
764.09
486.74
mg/l
0.53
23
189
14
115
1.22
0.23
1.1
1.1
0.86
3.99
u/ml
—
6
46
13
106
1.23
0.23
1.0
1.1
1.63
1.48
g/l
0.66
13
98
57
618
0.92
0.23
8.1
9.9
—
—
—
0
0
5
41
1.22
0.22
1.4
1.4
39.02
28.87
umol/l
—
5
36
0
11
0.00
0.21
0.0
2.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
1.73
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
1.41
—
0
5
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
11
89
1.24
0.21
1.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
75
707
1.07
0.18
3.0
3.5
7.38
7.38
ph
0.19
45
385
11
132
0.83
0.18
1.7
2.0
—
—
—
0
0
16
139
1.15
0.16
4.3
3.6
35.25
25.08
mg/l
—
8
98
8
100
0.80
0.13
1.0
1.2
—
—
—
0
0
15
132
1.14
0.13
1.1
1.1
1.06
1.23
u/ml
—
6
51
208
2037
1.03
0.11
1.4
1.4
—
—
—
0
0
13
115
1.13
0.10
2.2
1.8
—
—
—
0
0
5
44
1.14
0.10
1.2
1.1
743.20
1656.98
miu/ml
—
5
44
117
1202
0.97
0.09
3.5
3.0
0.62
0.77
ug/l
1.91
87
724
6
54
1.11
0.09
1.2
1.0
—
—
—
0
0
24
224
1.07
0.08
1.6
1.9
5.06
4.94
iu/l
—
7
103
34
322
1.06
0.08
1.2
1.1
1.44
1.56
g/l
1.61
34
322
5
60
0.83
0.08
1.0
1.0
255.80
303.93
ng/l
—
5
43
29
273
1.06
0.08
2.7
1.7
—
—
—
0
0
29
273
1.06
0.08
1.4
1.5
—
—
—
0
0
6
70
0.86
0.07
1.2
1.1
—
—
—
0
0
55
530
1.04
0.07
1.4
1.2
—
—
—
0
0
8
76
1.05
0.07
1.0
1.6
—
—
—
0
0
17
157
1.08
0.07
1.1
1.1
1.32
2.07
u/ml
—
9
83
22
206
1.07
0.07
3.2
1.7
—
—
—
0
0
29
275
1.06
0.06
2.7
1.7
—
—
—
0
0
21
224
0.94
0.06
1.0
1.2
—
—
—
0
0
14
128
1.10
0.06
1.0
1.1
0.26
1.64
u/ml
—
6
63
326
3229
1.02
0.06
1.9
1.9
1.44
1.35
mmol/l
0.85
299
2753
15
138
1.09
0.06
1.1
1.1
1.20
74.20
iu/ml
—
5
24
20
187
1.07
0.06
1.4
1.1
—
—
—
0
0
29
276
1.05
0.06
2.7
1.7
—
—
—
0
0
13
119
1.09
0.06
1.7
1.2
—
—
—
0
0
21
222
0.94
0.05
1.5
1.3
—
—
—
0
0
41
424
0.97
0.05
5.5
10.4
25.78
24.90
mmol/l
0.84
41
419
18
191
0.94
0.04
4.4
2.4
—
—
—
0
0
12
130
0.92
0.04
1.5
1.7
—
—
—
0
0
78
795
0.98
0.04
1.3
1.4
—
—
—
0
0
12
111
1.08
0.04
1.1
1.1
1.06
2.38
eliau/ml
—
7
54
16
151
1.06
0.03
1.1
1.5
—
—
—
0
0
34
330
1.03
0.03
1.2
1.1
0.87
0.89
g/l
0.37
34
330
40
410
0.97
0.02
1.1
1.1
—
—
—
0
0
70
691
1.01
0.01
3.0
3.5
1.93
1.82
mmol/l
0.07
62
595
17
163
1.04
0.01
1.1
1.1
—
—
—
0
0
17
163
1.04
0.01
1.1
1.1
—
—
—
0
0
26
254
1.02
0.00
2.9
1.7
—
—
—
0
0
20
203
0.98
0.00
1.1
1.1
—
—
—
0
0
13
131
0.99
0.00
1.2
1.4
—
—
—
0
0
12
115
1.04
0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
0.03
—
0
6
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
89
1.01
-0.00
1.1
1.1
—
—
—
0
0
18
180
1.00
-0.00
3.9
4.7
—
—
—
0
0
9
99
0.91
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
28.00
—
0
5
0
9
0.00
-0.00
0.0
4.8
—
0.14
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
486.02
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
71.88
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
379.00
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
189.80
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint ARTHRO_SPEC and mortality.

Females

Parameter HR [95% CI] p-value
ARTHRO_SPEC 1.041 [0.88, 1.23] 0.631
Birth year 0.997 [0.99, 1.01] 0.483

During the follow-up period (1.1.1998 — 31.12.2019), 205 out of 1773 females with ARTHRO_SPEC died.

Males

Parameter HR [95% CI] p-value
ARTHRO_SPEC 1.271 [1.08, 1.5] 0.005
Birth year 0.989 [0.98, 1.0] 0.031

During the follow-up period (1.1.1998 — 31.12.2019), 220 out of 1252 males with ARTHRO_SPEC died.

Mortality risk

Mortality risk for people of age

years, who have ARTHRO_SPEC.

N-year risk Females Males
1 0.123% 0.28%
5 0.608% 1.685%
10 1.514% 4.008%
15 3.05% 7.209%
20 5.688% 12.403%

Relationships between endpoints

Index endpoint: ARTHRO_SPEC – Other specific arthropathies, wide

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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