glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519870 |
1. Apply sex-specific ruleNone |
519870 |
2. Check conditionsNone |
519870 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
241 |
4. Check minimum number of eventsNone |
241 |
5. Include endpointsNone |
241 |
6. Filter based on genotype QC (FinnGen only) |
233 |
Control definitions (FinnGen only)
- Control exclude
- H7_GLAUCOMA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H40
- Name in latin
- Glaucoma [secundarium] posttraumaticum
Similar endpoints
↥List of similar endpoints to
Glaucoma secondary to eye trauma
based on the number of shared cases.
Similar with more cases:
- Glaucoma
- Diseases of the eye and adnexa
- Any operation in hilmo
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2393 | 862 | 1511 |
| Only index persons | 2107 | 772 | 1335 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.02 | 0.04 |
| Only index persons | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 61.99 | 69.56 | 57.65 |
| Only index persons | 60.89 | 68.48 | 56.50 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 233 | 89 | 144 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.07 |
| Median age at first event (years) | 61.62 | 59.40 | 63.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 241
- Matched controls
- 2410
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
16384.0
308.2
226
*
S01ED51
ATC
timolol, combinations; ophthalmic
187.5
307.7
182
39
114
Kela drug reimbursment
Glaucoma
251.3
307.7
186
32
S01EE01
ATC
latanoprost; ophthalmic
139.0
263.9
138
23
S01ED01
ATC
timolol; ophthalmic
139.6
233.4
120
17
S01EC01
ATC
acetazolamide; systemic
112.5
157.8
82
11
XCK00
NOMESCO Finland
Perimetry
36.9
129.4
88
37
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
585.4
111.1
102
*
S01EC04
ATC
brinzolamide; ophthalmic
225.9
98.7
96
7
S01EA05
ATC
brimonidine; ophthalmic
375.7
98.6
93
*
S01EE05
ATC
tafluprost; ophthalmic
55.7
84.4
49
11
H40.0
ICD-10 Finland
Glaucoma suspect
156.9
82.1
83
8
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
+∞
80.9
73
*
S01EX03, ,
ATC
230.5
68.0
67
*
WX140
NOMESCO Finland
Parabulbar anesthesy
14.2
53.7
54
48
Z96.1
ICD-10 Finland
Presence of intraocular lens
7.6
52.3
105
223
S01EC03
ATC
dorzolamide; ophthalmic
305.8
50.1
49
*
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
+∞
45.2
42
*
XCH00
NOMESCO Finland
Eye pressure measurement
12.5
43.6
47
46
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
+∞
43.0
40
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.6
43.0
75
135
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
6.2
42.0
166
631
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
+∞
40.8
38
*
S01EE03
ATC
bimatoprost; ophthalmic
104.2
40.3
43
5
S01EE04
ATC
travoprost; ophthalmic
126.5
40.2
42
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
6.9
33.5
61
113
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
10.8
32.7
38
41
XCK10
NOMESCO Finland
Photography of fundus of eye
6.0
30.1
64
137
H40.9
ICD-10 Finland
Glaucoma, unspecified
329.6
29.5
29
*
S01EC54
ATC
brinzolamide, combinations; ophthalmic
329.6
29.5
29
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.4
27.4
156
714
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.7
27.2
84
246
CHD00
NOMESCO Finland
Laser trabeculoplasty
290.0
26.2
26
*
S01ED02
ATC
betaxolol; ophthalmic
151.3
26.2
27
*
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
+∞
25.5
24
*
S01BA01
ATC
dexamethasone; ophthalmic
9.4
23.7
30
36
H20.1
ICD-10 Finland
Chronic iridocyclitis
72.4
23.3
26
*
3656E
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POSTTRAUMATICUM]
+∞
23.3
22
*
S01EB01
ATC
pilocarpine; ophthalmic
88.6
22.1
24
*
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
25.2
20.9
29
13
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
+∞
20.1
19
*
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
+∞
20.1
19
*
CHC05
NOMESCO Finland
Iridotomy
114.5
19.9
21
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
6.7
19.8
34
58
H26.1
ICD-10 Finland
Traumatic cataract
50.6
19.6
23
5
H26.4
ICD-10 Finland
After-cataract
4.5
19.4
56
152
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.8
19.4
50
124
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
+∞
19.0
18
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.2
18.9
60
175
S01BA07
ATC
fluorometholone; ophthalmic
25.2
18.2
25
11
S01EA03
ATC
apraclonidine; ophthalmic
40.1
17.9
22
6
H40
ICD-10 Finland
Glaucoma
+∞
17.9
17
*
CHD99
NOMESCO Finland
Other filtering operation
+∞
17.9
17
*
37520
ICD-8 Finland
Glaucoma, Secondary
+∞
16.9
16
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
17.0
16.6
26
17
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
32.7
16.4
21
7
ZXD20
NOMESCO Finland
Day surgery
4.1
16.0
51
148
S01EA02
ATC
dipivefrine; ophthalmic
+∞
15.8
15
*
XCH05
NOMESCO Finland
Eye pressure longterm registration
170.6
15.7
16
*
ZXA05
NOMESCO Finland
Left side
3.1
15.6
93
404
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.0
15.4
126
651
S01BC03
ATC
diclofenac; ophthalmic
18.0
15.1
23
14
H27.0
ICD-10 Finland
Aphakia
45.4
14.3
17
*
H40.8
ICD-10 Finland
Other glaucoma
+∞
13.7
13
*
S01BA04
ATC
prednisolone; ophthalmic
12.6
13.1
23
20
H04.10
ICD-10 Finland
Dry eye syndrome
3.7
12.3
43
132
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
19.3
12.2
18
10
CS494
NOMESCO Finland
Other visual field testing
20.2
11.8
17
9
H18.1
ICD-10 Finland
Bullous keratopathy
68.4
11.7
13
*
CHD35
NOMESCO Finland
Laser goniopuncture
+∞
11.5
11
*
H16.0
ICD-10 Finland
Corneal ulcer
4.9
11.5
27
61
H33.0
ICD-10 Finland
Retinal detachment with retinal break
5.7
11.3
22
42
H21.0
ICD-10 Finland
Hyphaema
114.8
10.5
11
*
S05.6
ICD-10 Finland
Penetrating wound of eyeball without foreign body
+∞
10.5
10
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
8.5
10.4
22
28
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
12.1
10.2
18
16
WX142
NOMESCO Finland
Sub-tenon anesthesy
27.3
9.9
13
5
H40.11
ICD-10 Finland
Low pressure glaucoma
57.4
9.7
11
*
ZXC20
NOMESCO Finland
Use of chemical agents
9.7
9.7
19
21
H34.8
ICD-10 Finland
Other retinal vascular occlusions
9.3
9.5
19
22
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
+∞
9.4
9
*
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
+∞
9.4
9
*
WX002
NOMESCO Finland
Sedation and analgesia
2.6
8.9
60
269
CFW99
NOMESCO Finland
Other operation on conjunctiva
93.2
8.5
9
*
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
10.0
8.4
16
17
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
8.4
8
*
S01EE51
ATC
latanoprost and netarsudil; ophthalmic
+∞
8.4
8
*
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
+∞
8.4
8
*
H44.5
ICD-10 Finland
Degenerated conditions of globe
+∞
8.4
8
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
8.4
8
*
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
+∞
8.4
8
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.3
8.3
34
115
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
34.6
8.1
10
*
XCW10
NOMESCO Finland
Assessment of vision
15.7
7.8
12
8
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
46.5
7.8
9
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
46.5
7.8
9
*
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
46.5
7.8
9
*
W22
ICD-10 Finland
Striking against or struck by other object(s)
3.7
7.5
25
74
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
82.5
7.5
8
*
H3603, E103,
ICD-10 Finland
82.5
7.5
8
*
H40.1
ICD-10 Finland
Primary open-angle glaucoma
+∞
7.3
7
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
7.3
7
*
3662A
ICD-9 Finland
Cataract, Traumatic cataract
+∞
7.3
7
*
3708
FHL
Trabeculectomy or equivalent
+∞
7.3
7
*
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
+∞
7.3
7
*
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
20.8
7.2
10
5
ZXA00
NOMESCO Finland
Right side
2.2
7.1
78
431
H16.9
ICD-10 Finland
Keratitis, unspecified
9.7
6.9
13
14
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
9.7
6.9
13
14
S01FA01
ATC
atropine; ophthalmic
17.3
6.8
10
6
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
7.2
6.6
15
22
H25.1
ICD-10 Finland
Senile nuclear cataract
2.1
6.6
93
563
TCG10
NOMESCO Finland
Removal of sutures from cornea
71.7
6.5
7
*
87001
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Non complicata (sive NUD)
71.7
6.5
7
*
87011
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Complicata
71.7
6.5
7
*
H26.2
ICD-10 Finland
Complicated cataract
14.8
6.5
10
7
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
14.8
6.5
10
7
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.6
6.4
22
66
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
9.6
6.4
12
13
Z3231
NOMESCO Finland
Registered nurse
2.1
6.3
79
456
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
3.6
6.3
21
62
87091
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Sequelae
+∞
6.3
6
*
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
+∞
6.3
6
*
3711
FHL
Cyclodiateria or cryocoagulation
+∞
6.3
6
*
TimeCodeWAS
↥TODO / Current known limitations:
- Only showing the top 500 codes, because showing all (sometimes 20k) makes the page too slow.
- Legend / how to read the glyphs.
- Proper column names.
- Show details (e.g. Fisher or Chi-square test, N cases and N controls) when clicking on a row.
- Explanation on the underlying data / how the TimeCodeWAS is done (e.g. matched cases / controls, eligibility).
- Download CSV not working.
- No filters and sorters.
- Limited amount of endpoints with TimeCodeWAS data.
- Cross-links to Risteys lab test pages for lab test codes.
OMOP Concept
ln(OR) -5y
ln(OR) -1y
ln(OR) -1m
ln(OR) d0
ln(OR) +1m
ln(OR) +1y
ln(OR) +5y
MCC -5y
MCC -1y
MCC -1m
MCC d0
MCC +1m
MCC +1y
MCC +5y
LabWAS
↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
140
1065
1.75
4.32
11.1
7.6
1.21
1.20
mmol/l
0.29
125
921
215
1897
2.24
3.80
22.6
18.8
25.51
26.15
mg/l
0.11
184
1619
220
1963
2.39
3.72
27.3
22.3
139.46
139.69
mmol/l
0.69
215
1933
96
679
1.69
3.70
3.3
2.7
54.99
68.09
u/l
0.76
87
633
184
1547
1.80
3.68
10.4
8.6
86.42
81.26
u/l
0.60
171
1459
220
1966
2.37
3.65
27.8
22.5
4.01
4.00
mmol/l
0.04
214
1934
223
2028
2.33
3.13
33.4
28.0
240.31
240.23
e9/l
0.01
218
1997
223
2028
2.33
3.13
33.4
27.9
4.44
4.45
e12/l
0.09
215
1992
122
955
1.56
2.93
7.9
6.7
1.21
1.21
mmol/l
0.00
116
877
138
1118
1.55
2.79
7.9
7.0
11.99
11.77
umol/l
0.06
127
1066
60
407
1.63
2.60
1.8
1.8
987.28
1259.62
nmol/l
1.59
44
315
55
366
1.65
2.57
3.1
3.2
0.88
0.82
mmol/l
2.74
50
347
57
383
1.64
2.56
1.9
2.0
—
—
—
0
0
6
11
5.56
2.56
4.2
1.9
108.67
121.03
ng/l
—
6
11
79
575
1.56
2.55
2.8
2.2
3.22
3.18
mg/l
0.04
71
498
8
22
3.72
2.38
1.3
1.4
—
—
—
0
0
24
127
1.99
2.36
1.7
1.5
—
—
—
0
0
17
81
2.18
2.18
1.5
1.9
—
—
—
0
0
60
428
1.54
2.08
5.4
3.9
213.64
269.73
ng/l
0.18
49
361
115
938
1.43
2.02
7.4
5.0
34.73
34.94
g/l
0.15
110
887
14
64
2.26
1.98
1.4
1.5
—
—
—
0
0
62
452
1.50
1.94
1.5
1.9
450.96
424.88
pmol/l
0.28
50
386
50
354
1.52
1.79
1.9
2.0
29.96
29.08
s
0.68
50
346
15
75
2.07
1.73
1.5
1.7
—
—
—
0
0
167
1489
1.40
1.58
5.5
4.2
15.11
13.28
mm/h
0.55
157
1375
212
1980
1.59
1.54
16.1
12.5
28.60
25.49
u/l
0.75
207
1924
91
741
1.37
1.52
5.1
4.0
16.89
10.61
mg/mmol
0.33
64
490
88
715
1.36
1.48
3.8
3.4
2.35
2.34
mmol/l
0.16
74
646
114
966
1.34
1.45
3.2
3.0
—
—
estimate
—
0
0
101
841
1.35
1.44
2.7
2.4
76.54
78.63
nmol/l
0.29
92
750
92
756
1.35
1.43
3.3
3.4
2399.62
1805.97
ng/l
0.34
80
645
189
1733
1.42
1.43
5.1
5.1
1.91
1.99
mu/l
0.40
166
1571
24
151
1.65
1.41
1.3
1.6
—
—
—
0
0
132
1147
1.33
1.40
11.3
10.2
4.29
4.35
e9/l
0.12
122
994
40
288
1.47
1.33
7.7
7.9
0.98
0.92
mmol/l
0.03
32
240
5
18
2.81
1.29
5.0
2.5
—
—
—
0
0
40
290
1.45
1.29
2.0
2.0
—
—
—
0
0
198
1842
1.42
1.27
6.2
5.4
6.37
6.11
mmol/l
1.31
176
1692
59
461
1.37
1.25
1.3
1.7
2.17
1.34
mg/l
0.63
50
370
6
25
2.43
1.25
1.7
1.4
—
—
—
0
0
38
275
1.45
1.23
1.9
2.1
—
—
—
0
0
16
94
1.75
1.20
4.3
2.1
44.81
37.66
u/l
0.69
16
84
28
193
1.51
1.15
3.9
2.7
4.97
6.17
ug/l
0.42
22
172
7
32
2.22
1.09
1.0
1.2
—
—
—
0
0
11
60
1.87
1.04
1.4
1.6
—
—
—
0
0
11
60
1.87
1.04
1.2
1.2
—
—
—
0
0
139
1247
1.27
1.04
3.8
3.4
82.53
53.09
u/l
1.12
124
1174
7
35
2.03
1.01
5.7
3.5
1.19
1.19
mmol/l
—
7
35
196
1842
1.34
0.99
22.0
17.9
72.29
76.66
ml/min/173m2
1.81
181
1720
110
964
1.26
0.99
6.2
5.7
2.61
2.82
ug/l
0.16
96
858
102
887
1.26
0.98
4.8
4.3
85.16
45.42
ng/l
0.41
80
679
7
36
1.97
0.98
5.7
3.4
109.00
105.11
mmol/l
—
7
36
122
1088
1.25
0.93
4.9
4.2
0.00
6.57
estimate
0.50
32
247
44
346
1.33
0.90
9.1
7.1
105.39
104.03
mmol/l
1.49
44
346
10
56
1.82
0.89
5.1
2.1
10.32
14.83
mg/l
—
10
51
114
1013
1.24
0.88
2.9
2.6
—
—
—
0
0
193
1823
1.29
0.84
5.6
5.3
1.34
1.42
mmol/l
1.54
172
1685
194
1834
1.30
0.84
5.6
5.4
4.35
4.46
mmol/l
0.73
175
1701
19
130
1.50
0.84
8.8
9.4
15.88
15.25
%
0.41
19
124
120
1077
1.23
0.83
4.9
4.1
0.00
0.00
estimate
-0.00
32
241
106
940
1.23
0.82
2.2
2.2
95.69
94.98
pmol/l
0.05
53
509
8
47
1.73
0.81
1.0
1.5
—
—
—
0
0
8
47
1.73
0.81
1.0
1.5
—
—
—
0
0
20
140
1.47
0.80
4.2
2.9
0.75
0.64
%
1.27
20
140
0
24
0.00
0.79
0.0
2.0
—
2.45
—
0
11
8
48
1.69
0.79
1.8
1.4
—
—
—
0
0
88
770
1.23
0.77
5.3
4.9
23.61
21.41
%
0.60
45
411
100
888
1.22
0.75
3.6
3.0
132.82
154.08
ug/l
0.60
89
828
185
1748
1.25
0.74
5.0
4.5
1.30
1.31
mmol/l
0.05
163
1608
121
1097
1.21
0.73
5.0
4.2
0.00
1.36
estimate
0.51
28
224
5
25
2.02
0.73
1.0
1.9
—
—
—
0
0
5
25
2.02
0.73
1.0
1.9
—
—
—
0
0
5
25
2.02
0.73
1.0
1.9
—
—
—
0
0
7
40
1.77
0.72
1.3
1.3
—
—
—
0
0
20
144
1.42
0.70
4.2
2.9
0.96
1.13
%
0.91
20
144
7
41
1.73
0.70
1.3
1.6
—
—
—
0
0
10
61
1.67
0.69
1.8
2.1
92.70
87.87
%
—
10
61
190
1805
1.25
0.69
9.0
7.0
42.16
40.47
mmol/mol
1.49
171
1690
95
848
1.20
0.67
5.4
4.2
0.00
0.04
estimate
0.96
28
199
196
1871
1.25
0.67
6.7
6.2
2.52
2.58
mmol/l
0.45
176
1733
10
62
1.64
0.66
1.3
1.2
0.25
0.23
g/l
—
10
62
10
63
1.61
0.63
1.3
1.3
1.15
1.15
g/l
—
10
63
64
555
1.21
0.60
3.5
3.0
345.96
358.76
umol/l
0.46
50
480
41
339
1.25
0.60
1.2
1.3
29.31
33.80
iu/ml
—
10
103
8
53
1.53
0.59
3.9
1.7
—
—
—
0
0
59
510
1.21
0.58
2.9
2.7
—
—
—
0
0
10
65
1.56
0.56
2.5
2.4
95.00
69.26
ug/min
—
5
40
22
169
1.33
0.55
1.5
1.4
—
—
—
0
0
72
637
1.19
0.55
5.0
3.9
0.00
0.01
estimate
0.50
30
213
31
251
1.27
0.54
6.4
7.9
—
—
—
0
0
7
45
1.57
0.49
1.0
1.2
—
—
—
0
0
69
769
0.86
0.48
1.9
1.9
1.30
1.37
mmol/l
0.41
54
629
51
446
1.18
0.45
3.0
3.0
2.49
2.45
mmol/l
0.89
41
402
16
122
1.33
0.43
1.6
2.0
1.45
1.50
g/l
0.09
11
114
20
158
1.29
0.43
2.7
3.6
1.85
1.90
mmol/l
0.02
13
112
5
32
1.57
0.42
1.6
1.1
—
18.86
—
0
7
5
32
1.57
0.42
3.8
5.1
—
—
—
0
0
15
114
1.34
0.42
1.1
1.2
134.01
440.17
u/ml
1.09
15
105
0
16
0.00
0.41
0.0
1.3
—
8.57
—
0
16
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
8
60
1.34
0.40
1.0
1.4
—
3.27
—
0
15
68
614
1.15
0.40
3.9
3.6
0.74
0.54
e6/l
0.18
54
468
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
9
67
1.36
0.38
1.2
1.6
—
—
—
0
0
5
36
1.40
0.38
2.6
3.7
6.34
10.78
pmol/l
—
5
36
6
41
1.47
0.36
1.0
1.4
—
—
—
0
0
9
122
0.73
0.36
2.7
2.4
—
—
—
0
0
6
42
1.44
0.36
1.0
1.0
—
4.15
—
0
6
35
305
1.17
0.33
1.1
1.3
31.33
14.04
u/ml
0.32
13
107
67
613
1.13
0.33
4.9
3.6
0.05
0.14
estimate
0.28
21
187
48
430
1.15
0.32
1.3
1.2
0.51
1.85
u/ml
1.65
12
120
7
52
1.36
0.31
2.1
1.2
0.73
0.88
nmol/l
—
7
43
12
93
1.31
0.30
2.1
2.7
—
—
—
0
0
27
232
1.18
0.30
3.9
3.7
—
—
—
0
0
7
55
1.28
0.30
1.3
1.7
185.86
206.32
pmol/l
—
7
50
7
56
1.26
0.29
1.9
2.5
247.57
204.68
%
—
7
56
7
57
1.23
0.29
1.0
1.3
—
—
—
0
0
61
561
1.12
0.28
3.4
3.2
0.81
0.82
ug/l
0.06
41
362
30
263
1.16
0.27
5.0
5.0
28.57
32.03
%
0.71
21
177
8
67
1.20
0.26
1.3
1.6
—
—
—
0
0
9
77
1.18
0.24
1.0
1.3
—
—
—
0
0
5
38
1.32
0.23
1.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
3.29
—
0
7
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
11
89
1.25
0.21
1.5
2.4
3.94
3.08
g/l
0.77
11
80
0
13
0.00
0.21
0.0
5.2
—
85.08
—
0
13
16
137
1.18
0.19
1.6
1.7
—
—
—
0
0
145
1411
1.07
0.17
4.3
4.1
14.84
14.92
pmol/l
0.13
128
1270
22
198
1.12
0.15
3.0
3.0
66.27
66.45
g/l
0.06
22
179
8
98
0.81
0.14
5.1
3.0
7.63
1124.17
u/ml
—
8
83
39
365
1.08
0.13
3.7
3.2
2.83
1.04
e6/l
0.80
24
214
9
110
0.81
0.13
2.6
2.2
—
—
—
0
0
11
96
1.15
0.10
1.5
2.4
8.65
7.45
g/l
0.97
11
87
11
96
1.15
0.10
1.5
2.4
4.09
4.23
g/l
0.23
11
87
11
96
1.15
0.10
1.5
2.4
3.96
4.01
g/l
0.03
11
87
5
44
1.14
0.10
1.6
1.7
—
—
—
0
0
5
45
1.11
0.10
1.0
1.3
25.18
23.33
iu/l
—
5
38
6
58
1.04
0.08
1.3
1.4
—
—
—
0
0
5
62
0.80
0.08
1.6
1.6
—
—
—
0
0
5
63
0.79
0.08
1.4
1.4
—
—
—
0
0
46
479
0.95
0.08
6.6
4.3
1.02
1.02
kg/l
0.14
31
331
9
85
1.06
0.07
1.2
2.5
10.62
10.21
g/l
—
9
75
8
92
0.87
0.07
1.0
1.3
—
—
—
0
0
11
100
1.10
0.05
1.5
1.8
3.95
3.50
mmol/l
—
6
77
28
268
1.05
0.05
1.9
1.5
—
—
—
0
0
33
340
0.97
0.03
3.8
3.4
2.96
1.94
e6/l
0.23
18
191
18
172
1.05
0.02
2.4
3.3
67.33
61.21
ml/min/173m2
—
6
75
10
93
1.08
0.02
1.0
1.0
—
—
—
0
0
19
186
1.02
0.00
1.5
1.5
—
—
—
0
0
64
645
0.99
0.00
1.8
1.8
21.74
20.55
nmol/l
0.18
50
538
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
5.6
—
168.20
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.0
—
132.20
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
-0.00
1.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
1.6
1.7
—
—
—
0
0
6
63
0.95
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.3
—
55.56
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
35.47
—
0
6
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
45.43
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
69
0.87
-0.00
1.3
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
1540.57
—
0
7
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
8
0.00
-0.00
0.0
4.4
—
107.63
—
0
8
0
8
0.00
-0.00
0.0
1.8
—
75.86
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.3
—
13.24
—
0
7
5
52
0.96
-0.00
1.6
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_GLAUCSECTRAUMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCSECTRAUMA | 1.083 [0.92, 1.27] | 0.327 |
| Birth year | 0.994 [0.99, 1.0] | 0.134 |
During the follow-up period (1.1.1998 — 31.12.2019), 277 out of 736 females with H7_GLAUCSECTRAUMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCSECTRAUMA | 1.166 [0.99, 1.37] | 0.061 |
| Birth year | 0.984 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 1144 males with H7_GLAUCSECTRAUMA died.
Mortality risk
Mortality risk for people of age
years, who have H7_GLAUCSECTRAUMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.096% | 0.217% |
| 5 | 0.64% | 1.213% |
| 10 | 1.766% | 3.075% |
| 15 | 3.328% | 5.942% |
| 20 | 5.542% | 9.904% |
Relationships between endpoints
↥Index endpoint: H7_GLAUCSECTRAUMA – Glaucoma secondary to eye trauma
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data