Ulcerative enterocolitis

ULCERENTER

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K51.0
  • Cause of death: ICD-10 K51.0

2 out of 7 registries used, show all original rules.

1352

4. Check minimum number of events

None

1352

5. Include endpoints

None

1352

6. Filter based on genotype QC (FinnGen only)

1232

Control definitions (FinnGen only)

Control exclude
K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K51
Name in latin
Enterocolitis ulcerosa [chronica]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7478 3539 3905
Only index persons 6872 3325 3547
Unadjusted period prevalence (%)
Whole population 0.11 0.10 0.11
Only index persons 0.13 0.12 0.14
Median age at first event (years)
Whole population 43.87 41.69 45.68
Only index persons 42.10 40.37 43.72

-FinnGen-

Key figures

All Female Male
Number of individuals 1232 665 567
Unadjusted period prevalence (%) 0.25 0.24 0.26
Median age at first event (years) 42.32 36.75 48.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1273
Matched controls
12730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
+∞
312.8
287
*
L04AX01
ATC
azathioprine; systemic
140.3
307.7
673
101
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
307.7
1150
*
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
17.1
307.7
441
383
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
5801.2
307.7
888
5
UJF32
NOMESCO Finland
Coloscopy
25.5
307.7
1006
1638
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
307.7
398
*
K51.8
ICD-10 Finland
Other ulcerative colitis
6681.2
307.7
454
*
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
307.7
1271
*
H02AB07
ATC
prednisone; oral
11.3
307.7
553
810
A07EA06
ATC
budesonide; oral, local oral
256.4
307.7
569
40
K51.5
ICD-10 Finland
Left sided colitis
16384.0
307.7
823
*
UJF30
NOMESCO Finland
Ileoscopy through colon
21.3
307.7
608
524
A07EA02
ATC
hydrocortisone; rectal
486.5
307.7
552
20
A07EC01
ATC
sulfasalazine; oral, rectal
13.1
307.7
422
465
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
307.7
485
*
A07EC02
ATC
mesalazine; oral, rectal
1774.8
307.7
1111
49
K51
ICD-10 Finland
Ulcerative colitis
1116.7
282.5
266
*
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
118.9
271.1
138
13
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
35.6
270.0
173
56
H02AB06
ATC
prednisolone; systemic
9.9
267.5
1058
4227
K50.9
ICD-10 Finland
Crohn disease, unspecified
1022.7
262.2
248
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
2718.8
252.7
236
*
K50.8
ICD-10 Finland
Other Crohn disease
+∞
249.4
231
*
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
93.1
240.6
126
15
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.9
220.9
713
2261
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
627.9
219.3
211
*
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
218.2
203
*
K50.0
ICD-10 Finland
Crohn disease of small intestine
+∞
192.7
180
*
J01MA02
ATC
ciprofloxacin; systemic
5.4
190.2
808
3120
L01BB02
ATC
mercaptopurine; oral
258.3
177.3
178
8
P01AB01
ATC
metronidazole; oral, rectal
4.7
156.6
816
3529
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
15.1
155.9
143
106
ZX120
NOMESCO Finland
Intravenous
6.6
155.5
292
548
K83.0
ICD-10 Finland
Cholangitis
25.5
155.0
110
47
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
51.8
150.8
87
18
A07EA01
ATC
prednisolone; oral, rectal
777.2
143.9
139
*
D94
ICPC
Chronic enteritis/ulcerative colitis
323.1
143.6
143
5
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
10.6
143.2
166
177
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
1420.6
133.8
128
*
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
59.5
130.1
73
13
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.9
122.9
557
2097
L04AB04
ATC
adalimumab; parenteral
13.1
122.5
121
101
A07DA03
ATC
loperamide; oral
11.2
122.1
135
134
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
1273.9
120.9
116
*
A05AA02
ATC
ursodeoxycholic acid; oral
14.3
116.5
109
83
UJF92
NOMESCO Finland
Capsular endoscopy
17.0
115.8
98
62
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
112.2
106
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.8
106.6
455
1619
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
104.6
99
*
JFF10
NOMESCO Finland
Loop enterostomy
41.9
99.2
60
15
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
98.2
93
*
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
15.3
91.9
82
57
WX302
NOMESCO Finland
Thoracal epidural anesthesy
6.7
88.8
151
251
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.6
86.9
239
611
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
13.4
84.4
81
64
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
82.2
78
*
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
82.2
78
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
5.4
80.2
175
368
H02AB09
ATC
hydrocortisone; systemic
9.9
80.2
95
103
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.5
78.2
220
570
A07EC03
ATC
olsalazine; oral
+∞
77.9
74
*
A07AA09
ATC
vancomycin; oral
19.6
76.5
60
32
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.3
76.0
388
1503
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
22.9
75.0
55
25
TJF80
NOMESCO Finland
Ostomy education
20.2
75.0
58
30
L04AA01
ATC
[U] ciclosporin
17.1
74.1
62
38
C10AC01
ATC
colestyramine; oral
8.9
71.4
92
111
L04AD01
ATC
ciclosporin; systemic
10.2
68.7
79
82
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
14.1
67.7
63
47
WX002
NOMESCO Finland
Sedation and analgesia
3.2
67.6
336
1271
K56.7
ICD-10 Finland
Ileus, unspecified
12.1
67.6
69
60
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
62.2
696
3996
K50
ICD-10 Finland
Crohn disease [regional enteritis]
+∞
60.9
58
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.4
58.9
257
892
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
7.7
56.0
81
112
L04AC05
ATC
ustekinumab; parenteral
81.5
55.5
62
8
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
17.9
55.1
45
26
L04AB02
ATC
infliximab; parenteral
72.2
54.6
62
9
A06AC01
ATC
ispaghula (psylla seeds); oral
2.7
54.6
405
1878
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
54.6
588
3257
3042, ,
Kela drug reimbursment
+∞
53.5
51
*
JAH00
NOMESCO Finland
Laparotomy
6.8
53.3
86
134
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
53.3
253
920
H02AB04
ATC
methylprednisolone; systemic
3.1
53.0
263
981
253, ,
Kela drug reimbursment
+∞
52.5
50
*
1370
FHL
Colonoscopy, whole colon
86.8
52.4
58
7
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
9.0
51.6
65
76
Z93.2
ICD-10 Finland
Ileostomy status
85.3
51.3
57
7
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.9
50.9
162
454
3AC01, ,
NOMESCO Finland
15.0
50.4
45
31
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
20.1
50.4
39
20
J01MA12
ATC
levofloxacin; systemic
2.8
48.3
301
1267
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
9.7
48.3
57
61
UJG02
NOMESCO Finland
Proctoscopy
8.0
47.9
66
86
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
7.3
47.4
71
102
4AA12, ,
NOMESCO Finland
166.1
46.1
48
*
A02BC02
ATC
pantoprazole; systemic
2.5
45.9
946
6786
K60.3
ICD-10 Finland
Anal fistula
7.5
45.7
67
94
JFH10
NOMESCO Finland
Total colectomy and ileostomy
463.7
45.6
45
*
L04AG05
ATC
vedolizumab; parenteral
+∞
45.1
43
*
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
+∞
45.1
43
*
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.2
44.0
125
322
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
5.1
43.9
96
200
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
5.8
40.9
77
140
R50.9
ICD-10 Finland
Fever, unspecified
2.7
40.1
268
1159
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
8.6
40.0
52
63
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
+∞
39.8
38
*
N02AX02
ATC
tramadol; systemic, rectal
2.1
38.1
605
3783
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
6.7
37.8
61
95
K56.0
ICD-10 Finland
Paralytic ileus
12.7
36.8
36
29
JHA00
NOMESCO Finland
Anal or perianal incision
7.4
36.7
54
76
JFB00
NOMESCO Finland
Partial resection of small intestine
8.9
35.9
45
52
L04AB06
ATC
golimumab; parenteral
11.9
35.3
36
31
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
10.6
35.2
39
38
JHD00
NOMESCO Finland
Anal dilatation
13.5
34.9
33
25
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
97.9
34.9
38
*
256, ,
Kela drug reimbursment
+∞
34.5
33
*
E86
ICD-10 Finland
Volume depletion
6.2
34.4
60
101
ZXD05
NOMESCO Finland
Urgent procedure
2.1
34.0
458
2661
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
33.5
32
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.0
33.0
97
255
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.8
33.0
184
721
ZXE20
NOMESCO Finland
More than three and less than five hours
2.7
32.9
210
882
UJK02
NOMESCO Finland
ERCP
5.7
32.8
62
113
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
+∞
32.4
31
*
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
+∞
32.4
31
*
B01AB05
ATC
enoxaparin; parenteral
2.1
32.3
418
2382
4AB02, ,
NOMESCO Finland
63.4
32.2
37
6
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
73.9
32.0
36
5
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.8
32.0
178
696
K61.0
ICD-10 Finland
Anal abscess
6.4
32.0
54
88
Z2221
NOMESCO Finland
Medical doctor
2.1
31.8
405
2291
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.2
31.1
65
130
L01BA01
ATC
methotrexate; systemic
4.8
30.9
72
158
C05AA08
ATC
fluocortolone; rectal, topical
2.6
30.8
200
845
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.7
30.0
184
756
M05BA04
ATC
alendronic acid; oral
3.5
30.0
111
342
WVA20
NOMESCO Finland
Medicine administration
4.9
29.9
68
146
A02BC01
ATC
omeprazole; systemic
2.1
29.9
369
2056
L04AA33
ATC
[U] vedolizumab
+∞
29.3
28
*
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
29.3
28
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
28.3
362
2037
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
28.2
27
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.7
27.8
164
659
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.2
27.4
116
388
ZXE00
NOMESCO Finland
One hour or less
1.9
27.2
523
3387
L04AX03
ATC
methotrexate; systemic
2.7
27.1
160
643
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.8
27.1
62
134
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
46.8
26.6
32
7
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
8.0
26.5
36
46
1490
FHL
Sigmoideoscopy (fiberscope)
52.9
26.3
31
6
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
+∞
26.1
25
*
UJD02
NOMESCO Finland
Gastroscopy
3.7
25.8
84
237
K92.1
ICD-10 Finland
Melaena
3.7
25.8
86
247
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
8.3
25.7
34
42
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
25.1
24
*
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
25.1
24
*
B03BA03
ATC
hydroxocobalamin; parenteral
3.6
25.0
87
257
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
25.0
484
3120
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.7
24.6
80
226
127
Kela drug reimbursment
Transplant complication
6.1
24.4
43
73
JF1BD
NOMESCO Finland
Very extensive small bowel CT
35.3
24.3
31
9
D64.9
ICD-10 Finland
Anaemia, unspecified
2.7
24.0
140
558
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
23.7
320
1820
D99
ICPC
Disease digestive system other
8.8
23.7
30
35
A07AA02
ATC
nystatin; oral
3.4
23.6
89
277
JFF13
NOMESCO Finland
Terminal enterostomy
34.1
23.4
30
9
SPAT1255
SPAT
Intravenous administration of medicine
3.1
23.2
103
354
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
18.9
23.1
35
19
WX402
NOMESCO Finland
General anaesthesia
2.0
22.8
325
1881
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.3
22.7
193
916
6419
FHL
Other measure in this category
122.2
22.6
24
*
L04AA06
ATC
mycophenolic acid; systemic
5.0
22.6
49
101
A02BC05
ATC
esomeprazole; systemic
1.8
22.5
516
3478
UJK12
NOMESCO Finland
Peroral cholangioscopy
63.7
21.9
25
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.1
21.8
93
312
Z94.4
ICD-10 Finland
Liver transplant status
22.7
21.8
31
14
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
81.6
21.7
24
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.0
21.5
102
364
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
21.4
279
1561
UJF02
NOMESCO Finland
Peroral enteroscopy
21.1
21.3
31
15
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
21.2
324
1915
RD210, ,
NOMESCO Finland
5.9
21.1
38
66
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
16.9
21.0
33
20
UJF34
NOMESCO Finland
Left colonoscopy
18.2
20.9
32
18
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
20.9
135
565
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
20.7
125
506
N03AX16
ATC
[U] pregabalin
2.0
20.7
297
1717
Z3231
NOMESCO Finland
Registered nurse
1.9
20.6
353
2163
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
20.6
443
2912
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
5.6
20.3
39
72
SPAT1262
SPAT
Handing over of treatment supplies
2.1
20.3
220
1149
JF1AD
NOMESCO Finland
Small bowel CT
17.6
20.1
31
18
WW500
NOMESCO Finland
Blood transfusion
3.6
20.0
67
193
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
+∞
19.8
19
*
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.6
19.7
67
195
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
19.8
19.6
29
15
A02BC03
ATC
lansoprazole; oral
1.8
19.3
351
2184
K59.1
ICD-10 Finland
Functional diarrhoea
3.0
19.3
86
296
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
4.2
19.1
51
125
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.2
19.0
79
261
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
+∞
18.8
18
*
D18
ICPC
Change in faeces/bowel movements
4.3
18.7
49
118
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
18.5
566
4074
L04AD02
ATC
tacrolimus; systemic
6.2
18.2
31
51
J02AC01
ATC
fluconazole; systemic
1.7
18.1
499
3489
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
53.3
18.0
21
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.8
17.9
90
331
JJC00
NOMESCO Finland
Allogenic transplantation of liver
27.1
17.8
24
9
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.4
17.8
126
550
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
37.3
17.6
22
6
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
4.9
17.6
39
82
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.5
17.6
61
180
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
17.5
477
3318
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
7.2
17.4
26
37
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
5.7
17.3
32
57
107
Kela drug reimbursment
Pernicious anaemia
5.5
17.2
33
61
5551A
ICD-9 Finland
Regional enteritis, Large intestine
+∞
16.7
16
*
4AA33, ,
NOMESCO Finland
+∞
16.7
16
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
16.7
152
739
JHD20
NOMESCO Finland
Incision of fistula-in-ano
6.2
16.4
28
46
R51.80
ICD-10 Finland
Headache
1.9
16.3
228
1298
D11
ICPC
Diarrhoea
2.1
16.0
174
906
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.3
15.7
60
188
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
+∞
15.7
15
*
1380
FHL
Colonoscopy, left side
+∞
15.7
15
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.7
15.6
49
135
WZC30
NOMESCO Finland
Teaching
1.9
15.6
218
1239
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
161.9
15.5
16
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.0
15.3
69
239
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.9
15.3
71
250
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
15.3
137
661
K85
ICD-10 Finland
Acute pancreatitis
5.0
15.0
32
65
A03CA02
ATC
clidinium and psycholeptics; oral
3.0
14.9
68
237
Z43.2
ICD-10 Finland
Attention to ileostomy
57.4
14.8
17
*
R11
ICD-10 Finland
Nausea and vomiting
2.3
14.5
120
561
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
14.4
554
4147
N02AA05
ATC
oxycodone; systemic
1.9
14.3
201
1141
ZXC86
NOMESCO Finland
Use of endoscopic device
17.2
14.3
22
13
A07AA11
ATC
rifaximin; oral
17.2
14.3
22
13
B01AB10
ATC
tinzaparin; parenteral
2.1
14.3
140
699
3005
Kela drug reimbursment
Tofacitinib
19.4
14.3
21
11
J01DB01
ATC
cefalexin; oral
1.8
14.2
1050
9203
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
5.2
14.1
29
57
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.4
14.1
97
417
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
4.3
13.9
36
86
M13.9
ICD-10 Finland
Arthritis, unspecified
2.3
13.9
109
497
B80
ICPC
Iron deficiency anaemia
3.6
13.9
45
127
R10.0
ICD-10 Finland
Acute abdomen
3.3
13.8
53
167
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
13.6
13
*
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
+∞
13.6
13
*
K52.80
ICD-10 Finland
(Hemorrhagic) colitis caused by antibiotics
+∞
13.6
13
*
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
141.5
13.5
14
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.2
13.5
122
591
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
13.4
138
702
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
21.4
13.3
19
9
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
13.2
179
1004
XF600
NOMESCO Finland
Bloodpressure measurement
2.5
13.2
85
355
C05AA01
ATC
hydrocortisone; rectal, topical
2.8
13.0
66
244
K76.9
ICD-10 Finland
Liver disease, unspecified
5.1
12.9
27
54
N05CF01
ATC
zopiclone; oral
1.6
12.9
364
2514
JJ5AT, ,
NOMESCO Finland
50.5
12.9
15
*
N06AA09
ATC
amitriptyline; systemic
2.2
12.8
112
534
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.4
12.8
94
417
D16
ICPC
Rectal bleeding
3.7
12.8
41
115
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
14.2
12.8
21
15
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
12.7
146
773
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.6
12.6
76
307
R4110
NOMESCO Finland
Physiotherapy
1.6
12.6
327
2209
OAB50, ,
SPAT
2.2
12.6
109
518
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
70.6
12.6
14
*
JF2AB
NOMESCO Finland
Colongraphy with X-ray
32.4
12.6
16
5
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.8
12.5
64
238
JH1CM
NOMESCO Finland
Perianal extensive MRI with 3 Tesla magnet
+∞
12.5
12
*
56902
ICD-8 Finland
Other diseases of intestines and peritoneum, Proctitis haemorrhagica (ulcerosa)
+∞
12.5
12
*
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
131.3
12.5
13
*
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
4.7
12.4
28
60
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
18.2
12.1
18
10
M45
ICD-10 Finland
Ankylosing spondylitis
3.6
12.1
39
110
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
12.0
268
1738
L04AF03
ATC
upadacitinib; oral
21.5
12.0
17
8
Z3226
NOMESCO Finland
Physiotherapist
1.8
11.9
214
1309
J05AB11
ATC
valaciclovir; oral
1.8
11.8
187
1100
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
11.7
181
1056
K83.1
ICD-10 Finland
Obstruction of bile duct
4.7
11.7
27
59
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
11.6
218
1348
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
11.6
262
1704
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
19.1
11.6
17
9
JKA20
NOMESCO Finland
Cholecystectomy
3.5
11.6
40
118
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
+∞
11.5
11
*
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
121.1
11.4
12
*
6525
FHL
Enterostomy occlusion
121.1
11.4
12
*
UJH02
NOMESCO Finland
Anoscopy
2.8
11.4
56
204
R15
ICD-10 Finland
Faecal incontinence
3.5
11.3
38
110
J01MA01
ATC
ofloxacin; systemic
2.2
11.3
102
493
RS221, ,
NOMESCO Finland
5.0
11.2
24
49
D50.8
ICD-10 Finland
Other iron deficiency anaemias
4.6
11.2
26
57
E0000UV, ,
ATC
1.5
11.2
499
3800
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
20.2
11.1
16
8
UKC02
NOMESCO Finland
Cystoscopy
1.8
11.0
169
983
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
10.9
504
3860
D95
ICPC
Anal fissure/perianal abscess
5.2
10.8
22
43
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.7
10.7
57
217
Z2446
NOMESCO Finland
Social worker
2.2
10.7
91
430
B81
ICPC
Anaemia vit B12/folate deficiency
2.9
10.6
48
167
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.0
10.6
120
632
D06BX01
ATC
metronidazole; topical
1.9
10.6
136
748
N02BE01
ATC
paracetamol; systemic, rectal
1.7
10.5
1097
9952
6408
FHL
Colectomy and ileostomy
+∞
10.4
10
*
6410
FHL
Panprococolectomy and ileostomy
+∞
10.4
10
*
A02BA02
ATC
ranitidine; systemic
1.7
10.4
204
1274
ZYC01
NOMESCO Finland
Remote contact by phone
2.2
10.4
90
428
M01AE01
ATC
ibuprofen; systemic, rectal
0.6
10.4
969
10626
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
12.2
10.4
18
15
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.5
10.3
62
251
K74.3
ICD-10 Finland
Primary biliary cirrhosis
9.7
10.3
20
21
B01AA03
ATC
warfarin; systemic
1.8
10.1
169
1008
A01AB04
ATC
amphotericin B; local oral
2.7
10.1
54
206
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
14.7
10.0
16
11
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.8
10.0
48
173
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
40.4
10.0
12
*
K43.0
ICD-10 Finland
Incisional hernia with obstruction, without gangrene
7.7
9.9
22
29
K29.7
ICD-10 Finland
Gastritis, unspecified
2.8
9.8
47
169
A41.9
ICD-10 Finland
Sepsis, unspecified
2.9
9.8
45
158
QBA10
NOMESCO Finland
Incision of skin of trunk
4.9
9.8
21
43
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.1
9.7
39
127
K91.8
ICD-10 Finland
Other postprocedural disorders of digestive system, not elsewhere classified
55.4
9.7
11
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.6
9.6
57
229
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
7.9
9.6
21
27
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.6
9.6
54
212
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
4.6
9.6
22
48
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.8
9.5
47
172
R01AD08
ATC
fluticasone; nasal
1.5
9.5
350
2544
JFA76
NOMESCO Finland
Closure of fistula of small intestine
100.8
9.4
10
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
9.4
896
7819
5604
FHL
Vascular preparation or cannulation in the operating room
30.3
9.4
12
*
5781B
ICD-9 Finland
Gastro-intestinal haemorrhage, Melaena[HAEMORRHAGIA EX ANO]
30.3
9.4
12
*
1310
FHL
Esophagogastroscopy
21.9
9.4
13
6
ZX198
NOMESCO Finland
Other local administration
7.0
9.3
22
32
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
9.3
86
420
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
9.3
370
2730
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.4
9.3
61
258
M05BB03
ATC
alendronic acid and colecalciferol; oral
4.2
9.2
24
58
L04AA29
ATC
[U] tofacitinib
13.8
9.2
15
11
ZX100
NOMESCO Finland
Oral
4.3
9.1
23
54
A06AC51
ATC
ispaghula, combinations; oral
2.5
9.1
57
236
N05BA04
ATC
oxazepam; oral
1.5
9.0
303
2153
ZY010
NOMESCO Finland
Hospital outpatient
2.2
9.0
77
365
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
8.9
160
973
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
18.7
8.9
13
7
Z93
ICD-10 Finland
Artificial opening status
24.2
8.9
12
5
K61.1
ICD-10 Finland
Rectal abscess
12.6
8.9
15
12
A02BA03
ATC
famotidine; systemic
3.0
8.8
38
129
J45.1
ICD-10 Finland
Nonallergic asthma
2.1
8.8
83
409
WW200
NOMESCO Finland
Immunization
2.9
8.8
39
135
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.6
8.7
49
192
TQW40
NOMESCO Finland
Remowal of suture of skin
2.1
8.7
88
445
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.5
8.7
29
84
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.5
8.7
29
84
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
3.4
8.7
30
89
J01FA10
ATC
azithromycin; systemic
1.4
8.7
702
5897
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.1
8.6
82
405
F54
ICD-10 Finland
Psychological and behavioural factors associated with disorders or diseases classified elsewhere
11.7
8.6
15
13
R06AE07
ATC
cetirizine; oral
1.4
8.6
522
4165
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
10.1
8.5
16
16
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
3.8
8.4
25
67
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
+∞
8.3
8
*
Z90.4
ICD-10 Finland
Acquired absence of other parts of digestive tract
+∞
8.3
8
*
JGB40
NOMESCO Finland
Excision of rectum and end ileostomy
+∞
8.3
8
*
JFG53
NOMESCO Finland
Revision of ileal pelvic pouch
+∞
8.3
8
*
5550A
ICD-9 Finland
Regional enteritis, Small intestine
+∞
8.3
8
*
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
+∞
8.3
8
*
5563A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctosigmoiditis
+∞
8.3
8
*
JL5AM
NOMESCO Finland
Bile and pancreas ducts simple MRI examination with 3 Tesla magnet
+∞
8.3
8
*
J01DA01
ATC
[U] cefalexin
1.4
8.3
727
6169
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
8.3
163
1017
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.8
8.3
40
145
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.3
8.3
59
259
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
2.9
8.2
37
129
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
3.7
8.2
25
68
C07AB07
ATC
bisoprolol; oral
1.4
8.1
483
3825
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
8.1
287
2057
TK800
NOMESCO Finland
Hemodialysis
3.3
8.1
30
93
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
33.6
8.1
10
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.8
8.1
40
147
JHD30
NOMESCO Finland
Incomplete incision of fistula-in-ano
11.8
8.1
14
12
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
17.3
8.1
12
7
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
8.1
122
706
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
9.0
8.0
16
18
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
3.1
8.0
33
109
WX600
NOMESCO Finland
Single shot through catheter
3.1
8.0
33
109
JFA70
NOMESCO Finland
Suture of small intestine
10.1
8.0
15
15
K65.0
ICD-10 Finland
Acute peritonitis
6.3
8.0
20
32
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.2
8.0
21
51
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
2.9
8.0
37
131
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
7.3
8.0
18
25
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.2
8.0
30
94
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
8.0
69
329
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
4.3
8.0
20
47
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
4.3
8.0
20
47
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
7.9
118
680
J01FF01
ATC
clindamycin; systemic
1.5
7.9
311
2278
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
7.9
210
1414
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.2
7.8
67
318
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.1
7.8
75
372
H26.3
ICD-10 Finland
Drug-induced cataract
8.5
7.8
16
19
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
10.9
7.8
14
13
J01FA06
ATC
roxithromycin; oral
1.4
7.8
452
3559
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.7
7.8
40
150
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.2
7.8
64
299
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
3.9
7.7
22
57
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
7.7
129
771
D07AC01
ATC
betamethasone; topical
1.4
7.6
406
3146
J05AB01
ATC
aciclovir; systemic
1.5
7.6
253
1788
M81.4
ICD-10 Finland
Drug-induced osteoporosis
11.9
7.6
13
11
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
11.9
7.6
13
11
N82.3
ICD-10 Finland
Fistula of vagina to large intestine
25.2
7.6
10
*
R03AC03
ATC
terbutaline; inhalant
1.7
7.6
158
1001
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.9
7.5
34
119
M05BX04
ATC
denosumab; parenteral
2.3
7.5
53
232
SPAT1125
SPAT
Stoma care and guidance
4.3
7.5
19
45
WX610
NOMESCO Finland
Patient controlled analgesia
7.2
7.5
17
24
1470
FHL
Rectoscopy
7.2
7.5
17
24
Z98.8
ICD-10 Finland
Other specified postsurgical states
3.7
7.5
23
63
R53
ICD-10 Finland
Malaise and fatigue
1.5
7.5
298
2185
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
7.4
168
1086
JFG96
NOMESCO Finland
Other operation on intestinal stoma or pouch
80.6
7.4
8
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
7.4
662
5594
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
7.4
168
1088
TGC00
NOMESCO Finland
Bronchial lavation
2.8
7.4
35
126
R03AC02
ATC
salbutamol; inhalant
1.4
7.4
661
5586
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.2
7.3
58
267
J01AA02
ATC
doxycycline; systemic
1.4
7.3
911
8128
Z93.3
ICD-10 Finland
Colostomy status
6.9
7.3
17
25
A01AB09
ATC
miconazole; local oral
1.9
7.3
89
482
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
7.3
237
1667
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
15.8
7.2
11
7
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
7.2
82
433
JN4AD
NOMESCO Finland
Body CT examination
1.8
7.2
118
700
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
7.2
251
1792
K65.9
ICD-10 Finland
Peritonitis, unspecified
20.1
7.1
10
5
L88
ICD-10 Finland
Pyoderma gangrenosum
20.1
7.1
10
5
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
4.1
7.1
19
47
N06AB04
ATC
citalopram; systemic
1.5
7.1
229
1607
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.0
7.1
70
352
S18
ICPC
Laceration/cut
1.4
7.1
520
4246
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
10.1
7.0
13
13
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.1
7.0
28
91
C03CA01
ATC
furosemide; systemic
1.5
7.0
251
1798
A10AB05
ATC
insulin aspart; parenteral
1.9
7.0
91
502
D01
ICPC
Abdominal pain/cramps general
1.7
7.0
142
893
N19
ICD-10 Finland
Unspecified kidney failure
2.6
7.0
40
159
SPAT1263
SPAT
Sampling
1.4
6.9
451
3605
JAD10
NOMESCO Finland
Repair of incisional hernia
5.9
6.9
18
31
E000001, ,
ATC
1.5
6.9
223
1564
S10
ICPC
Boil/carbuncle
2.0
6.9
77
404
Z94.0
ICD-10 Finland
Kidney transplant status
4.0
6.9
19
48
K60.4
ICD-10 Finland
Rectal fistula
13.9
6.9
11
8
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.1
6.9
65
321
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.2
6.9
58
274
A46
ICD-10 Finland
Erysipelas
1.6
6.9
153
985
J01CA04
ATC
amoxicillin; systemic
1.5
6.9
1000
9111
WX892
NOMESCO Finland
Monitored bed care
1.9
6.8
85
463
298, ,
Kela drug reimbursment
9.4
6.8
13
14
JF1CM
NOMESCO Finland
Small bowel extensive MRI with with high intensity magnet
40.3
6.8
8
*
A06AD11
ATC
lactulose; oral
1.7
6.8
133
830
S29
ICPC
Skin symptom/complaint other
1.5
6.7
220
1546
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
3.0
6.7
29
99
Z01.2
ICD-10 Finland
Dental examination
1.4
6.7
549
4547
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
6.7
224
1583
JWW96
NOMESCO Finland
Other reoperation in gastroenterological surgery
22.6
6.7
9
*
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
2.9
6.7
30
105
N06AX16
ATC
venlafaxine; oral
1.6
6.7
176
1181
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.5
6.6
39
157
KH1AD
NOMESCO Finland
CT of urinary organs
2.4
6.6
45
194
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
2.4
6.6
43
182
M02AA10
ATC
ketoprofen; topical
1.6
6.6
163
1077
K11.5
ICD-10 Finland
Sialolithiasis
3.3
6.6
24
74
N17.8
ICD-10 Finland
Other acute renal failure
4.2
6.6
17
41
N02BF02
ATC
pregabalin; oral
1.9
6.6
79
426
A04.9
ICD-10 Finland
Bacterial intestinal infection, unspecified
6.9
6.5
15
22
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.6
6.5
36
141
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
6.5
123
760
G43.9
ICD-10 Finland
Migraine, unspecified
1.8
6.4
87
487
SPAT1325
SPAT
Vaccination
1.4
6.4
322
2456
JF1DM
NOMESCO Finland
Very extensive MRI of small bowel (more than 1.5 T)
70.2
6.4
7
*
A07EB01
ATC
cromoglicic acid; oral
70.2
6.4
7
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
6.4
209
1468
3029
Kela drug reimbursment
Upadacitinib
8.2
6.3
13
16
M05BA07
ATC
risedronic acid; oral
3.1
6.3
25
81
K86.1
ICD-10 Finland
Other chronic pancreatitis
5.2
6.3
18
35
N05CF02
ATC
zolpidem; oral
1.5
6.3
197
1371
R4190
NOMESCO Finland
Nutritional therapy
2.2
6.3
50
231
J01MA14
ATC
moxifloxacin; systemic
1.8
6.3
98
574
5559X
ICD-9 Finland
Regional enteritis, Unspecified site
+∞
6.3
6
*
E87.6
ICD-10 Finland
Hypokalaemia
2.3
6.2
44
193
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
26.8
6.2
8
*
JAK03
NOMESCO Finland
Laparotomy and peritoneal irrigation
26.8
6.2
8
*
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
4.0
6.2
17
43
Z71.8
ICD-10 Finland
Other specified counselling
1.4
6.1
403
3213
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
6.1
70
371
JFB20
NOMESCO Finland
Ileocaecal resection
7.7
6.1
13
17
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.0
6.1
65
336
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
6.1
427
3439
D29
ICPC
Digestive symptom/complaint other
2.7
6.1
32
122
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.6
6.1
149
983
M04AA01
ATC
allopurinol; systemic
1.7
6.0
120
751
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
3.2
6.0
23
73
J01CF02
ATC
cloxacillin; systemic
3.0
6.0
26
89
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.7
6.0
108
658

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
919
1246
23.93
307.65
8.4
1.3
231.14
89.23
ug/g
16.96
873
965
793
1005
19.27
307.65
2.5
1.2
—
—
—
0
0
1012
4336
7.51
220.96
13.0
4.7
36.32
36.26
g/l
0.15
988
4094
858
3506
5.44
187.27
14.2
5.9
—
—
—
0
0
954
4778
4.98
146.62
4.9
2.4
75.12
75.38
nmol/l
0.11
922
4378
672
2624
4.31
145.68
4.4
2.1
2.93
2.77
mg/l
0.89
615
2277
983
5096
5.08
142.64
17.0
6.1
8.85
8.73
%
0.70
953
4802
979
5087
5.00
140.87
16.9
6.0
2.72
2.84
%
1.10
950
4784
974
5082
4.90
138.26
17.2
6.1
0.74
0.68
%
3.48
946
4774
977
5146
4.86
135.92
16.3
5.9
58.63
56.97
%
5.33
956
4934
1018
5541
5.18
135.20
17.2
6.0
0.04
0.04
e9/l
2.39
956
4810
1015
5530
5.12
134.14
17.3
6.0
0.58
0.57
e9/l
0.33
954
4796
983
5239
4.85
133.55
17.0
6.0
27.38
28.27
%
2.04
963
4990
1031
5731
5.20
131.38
17.4
6.3
0.18
0.19
e9/l
0.64
969
5038
1021
5659
5.06
129.92
17.3
6.0
1.81
1.99
e9/l
3.26
970
5027
1049
6173
4.97
116.88
19.9
9.3
4.07
4.08
e9/l
0.09
987
5385
411
1406
3.84
101.43
3.3
2.5
20.12
24.17
%
7.30
394
1318
455
1668
3.69
101.19
3.4
2.5
12.24
14.09
umol/l
5.91
437
1562
431
1539
3.72
99.53
3.3
2.4
2.43
2.34
g/l
2.41
409
1430
65
22
31.08
98.75
2.6
1.4
9.16
8.25
mg/l
0.26
56
17
306
891
4.20
94.26
6.6
4.7
0.61
0.68
%
0.19
105
255
133
190
7.70
89.98
6.3
3.0
4.00
4.30
e9/l
0.77
133
190
1164
8052
6.20
89.86
24.3
7.6
79.33
77.80
u/l
0.51
1154
7678
308
942
3.99
88.14
6.9
4.9
0.80
1.03
%
0.71
105
278
300
906
4.02
87.34
7.0
5.0
0.04
0.11
%
1.77
97
240
297
916
3.92
83.63
7.4
5.3
0.11
0.14
%
0.12
89
220
166
321
5.80
83.53
1.9
1.2
53.85
120.26
titre
2.95
13
38
141
243
6.40
79.82
6.3
2.9
57.80
57.28
%
0.16
141
243
239
667
4.18
76.96
2.3
1.8
1.20
1.32
g/l
0.71
222
619
277
864
3.82
76.21
3.2
2.9
11.25
10.59
g/l
2.14
253
799
286
939
3.64
72.63
4.5
2.4
0.23
0.22
g/l
4.23
268
876
700
3846
2.82
71.47
7.0
3.3
30.08
36.26
u/l
0.84
650
3654
107
178
6.47
62.45
2.5
1.7
0.77
0.87
g/l
0.27
90
139
382
1619
2.94
62.35
1.8
1.4
540.40
497.39
titre
0.20
100
329
340
1359
3.05
61.59
4.1
3.4
4.07
5.15
e9/l
1.49
302
1210
74
86
9.07
59.05
1.5
1.1
241.54
98.75
titre
—
26
8
196
572
3.87
58.49
1.6
1.2
—
—
—
0
0
846
5467
2.63
57.21
11.9
6.5
10.49
11.50
umol/l
2.69
826
5225
348
1484
2.85
55.33
1.6
1.7
—
—
—
0
0
736
4522
2.49
54.35
15.8
12.3
1.17
1.20
inr
1.18
648
3751
761
4810
2.45
51.83
23.6
10.6
0.00
0.00
e9/l
0.08
683
3959
832
5500
2.48
50.87
5.7
3.0
98.60
116.68
ug/l
1.61
794
5201
709
4411
2.37
49.06
9.1
6.4
1.22
1.21
mmol/l
2.45
679
4093
504
2712
2.42
48.55
6.5
4.3
—
—
—
0
0
682
4231
2.32
46.71
2.9
2.0
—
—
—
0
0
424
2145
2.46
46.46
1.7
1.7
—
—
—
0
0
765
5001
2.33
46.00
10.0
7.0
1.21
1.21
mmol/l
0.78
680
4331
147
419
3.84
44.95
2.1
1.5
3.81
12.71
iu/ml
—
22
8
134
358
4.07
44.87
1.9
1.2
—
—
—
0
0
483
2654
2.32
43.27
11.7
4.4
—
—
—
0
0
278
1215
2.65
40.82
6.3
2.9
6.85
8.01
umol/l
0.61
251
1066
316
1472
2.53
40.64
2.2
1.7
1119.73
1177.39
nmol/l
0.50
228
1145
556
3308
2.21
40.40
4.9
2.6
64.12
60.50
u/l
0.45
536
3098
242
1004
2.74
39.28
4.6
2.5
53.37
82.04
u/l
0.25
223
852
475
2683
2.23
38.95
9.1
4.0
95.36
91.48
%
2.96
459
2634
673
4431
2.10
36.42
2.5
2.0
97.53
96.20
pmol/l
0.32
449
2414
244
1060
2.61
35.89
3.3
2.9
1.99
1.82
%
1.26
223
959
122
356
3.68
35.87
6.5
3.3
49.68
4096.45
u/ml
0.84
107
310
53
78
7.05
34.55
2.1
1.6
—
—
—
0
0
70
140
5.23
33.46
3.8
3.9
0.82
1.36
%
1.13
60
131
38
39
10.01
33.10
3.7
3.0
0.59
0.61
mmol/l
0.57
38
39
467
2796
2.06
31.47
1.9
1.6
20.22
20.22
nmol/l
0.00
422
2420
369
2022
2.16
31.44
2.5
1.6
422.35
56228596.11
pmol/l
3.29
340
1718
30
0
+∞
31.38
2.2
0.0
2.74
—
mg/l
—
30
0
214
934
2.55
30.86
5.7
4.5
4.17
25.14
ug/l
1.60
166
762
88
228
4.07
30.55
1.2
1.3
341.64
248.63
u/ml
0.94
47
146
508
3192
1.98
29.43
11.5
5.9
—
—
—
0
0
477
2948
1.99
28.85
6.1
4.1
7.39
7.40
ph
1.01
386
2096
186
793
2.58
28.02
3.5
3.1
77.40
72.58
e9/l
0.70
143
586
289
1507
2.19
27.46
2.6
2.0
—
—
—
0
0
111
366
3.23
26.84
1.9
1.7
—
—
—
0
0
432
2637
1.97
26.64
1.9
2.0
—
—
—
0
0
49
88
5.75
26.30
1.1
1.1
—
—
—
0
0
229
1104
2.31
26.22
2.6
2.1
320.18
376.12
nmol/l
4.43
213
1030
314
1718
2.10
26.21
6.7
3.5
0.78
0.82
mmol/l
7.74
299
1642
216
1017
2.35
26.12
1.4
1.5
—
—
—
0
0
97
300
3.42
25.99
1.2
1.3
—
—
—
0
0
89
261
3.59
25.87
3.4
3.4
1.34
1.92
index
0.67
50
148
269
1395
2.18
25.75
1.5
1.2
—
—
—
0
0
195
887
2.42
25.45
10.0
7.9
10.26
9.12
mmol/l
1.31
187
854
257
1337
2.16
24.28
8.2
6.1
1.04
1.03
mmol/l
0.20
252
1243
387
2345
1.93
23.91
2.1
1.4
2.53
2.37
g/l
1.02
299
1526
69
181
3.97
23.53
5.9
4.0
51.16
336.81
u/ml
1.22
62
169
337
1971
1.97
22.98
3.4
2.7
520.70
540.62
mosm/kgh2o
0.86
310
1735
45
85
5.45
22.89
3.9
3.9
57.66
53.19
%
0.70
37
80
374
2294
1.89
21.96
3.4
2.5
5.47
5.77
e6/l
0.19
355
2081
913
7365
1.85
20.95
5.9
4.1
—
3.67
—
0
12
107
401
2.82
20.61
1.3
1.3
—
—
—
0
0
797
6200
1.76
20.39
7.9
4.9
6.76
6.63
mmol/l
0.78
773
5835
508
3485
1.76
20.30
3.9
2.3
—
—
—
0
0
491
3363
1.75
19.54
4.2
3.1
19.41
89.42
e6/l
2.62
422
2542
34
58
6.00
19.23
39.7
32.4
6.59
7.23
ug/l
0.82
29
52
404
2635
1.78
18.93
3.6
2.2
—
—
—
0
0
181
901
2.18
18.81
4.2
3.9
7.35
7.35
ph
0.16
156
656
189
964
2.13
18.44
7.5
3.4
7.36
7.38
ph
2.26
123
553
183
926
2.14
18.22
7.6
3.4
0.78
1.76
mmol/l
1.98
157
798
430
2885
1.74
18.10
4.1
3.0
0.52
0.39
e6/l
0.33
355
2078
1196
10796
2.78
17.97
37.7
13.7
17.42
22.84
mg/l
11.56
1103
8722
174
869
2.16
17.90
4.9
3.5
—
—
—
0
0
102
403
2.66
17.73
1.6
2.1
1.33
1.45
g/l
0.68
92
357
45
107
4.32
17.49
1.4
1.3
0.39
0.37
g/l
0.11
32
76
45
107
4.32
17.49
1.4
1.3
3.05
3.02
g/l
0.03
33
79
45
107
4.32
17.49
1.4
1.3
7.67
6.52
g/l
0.94
33
78
172
868
2.13
17.20
13.2
9.3
—
—
—
0
0
74
250
3.08
17.14
1.3
1.5
—
—
—
0
0
44
106
4.26
16.83
1.4
1.3
—
—
—
0
0
39
86
4.65
16.65
3.8
4.1
—
—
—
0
0
126
567
2.36
16.61
6.5
3.4
22.66
24.23
mmol/l
4.63
126
562
55
158
3.59
16.49
1.1
1.2
—
—
—
0
0
39
87
4.59
16.42
1.8
2.3
1345.94
1213.64
e6/l
0.29
33
81
75
264
2.96
16.18
1.6
1.1
—
—
—
0
0
539
3932
1.64
16.08
4.9
3.7
54.82
72.19
e6/l
0.49
437
2698
659
5067
1.62
15.79
4.2
2.7
—
—
estimate
—
0
0
144
715
2.14
14.95
5.0
4.1
108.32
84.36
ng/l
1.33
131
641
603
4584
1.60
14.80
3.6
3.2
6.02
6.18
ph
3.71
358
2652
66
232
2.95
14.29
1.3
1.5
131.36
149.23
au/ml
0.34
11
66
61
205
3.08
14.28
1.0
1.1
—
—
—
0
0
218
1280
1.85
13.98
2.2
1.7
—
—
—
0
0
720
5767
1.57
13.70
4.5
3.5
0.00
0.29
estimate
0.53
201
1098
161
863
1.99
13.57
1.5
1.4
—
—
—
0
0
29
61
4.84
13.11
1.8
2.3
497.45
490.08
e6/l
0.03
22
52
705
5673
1.54
12.73
4.4
3.5
0.00
0.00
estimate
0.50
201
1171
711
5739
1.54
12.61
4.5
3.5
7.99
6.94
estimate
0.04
206
1182
28
61
4.67
12.15
2.2
2.5
149.30
218.59
e6/l
0.87
23
56
57
209
2.81
11.47
1.1
1.1
—
—
—
0
0
354
2498
1.58
11.22
2.1
1.8
1.40
1.02
mg/l
0.89
283
1899
91
429
2.21
10.74
2.4
2.1
20.56
20.63
s
0.06
85
386
243
1583
1.66
10.62
2.7
2.1
30.29
29.28
s
1.83
236
1540
390
2845
1.53
10.55
3.5
2.8
—
—
—
0
0
815
6907
1.50
10.53
5.9
4.1
17.17
884.40
e6/l
1.55
12
98
250
1648
1.64
10.41
3.4
2.9
2.21
2.51
e6/l
0.24
137
781
70
299
2.42
10.38
1.5
1.4
243.45
307.99
ug/g
1.84
46
176
443
3343
1.50
10.12
3.6
3.3
—
0.67
—
0
9
96
475
2.10
10.03
2.2
2.0
8.34
7.99
iu/ml
0.04
25
115
219
1411
1.67
9.94
1.3
1.3
—
—
—
0
0
18
17
10.72
9.79
2.7
1.8
—
—
—
0
0
261
1785
1.58
9.25
3.5
2.7
0.71
0.99
e6/l
1.41
152
912
111
599
1.93
9.13
2.1
2.6
—
—
—
0
0
33
101
3.33
9.07
1.2
1.1
291.79
283.99
mg/l
0.19
33
92
1161
10806
1.85
8.85
31.5
15.8
139.28
139.67
mmol/l
6.12
1146
10611
67
309
2.23
8.38
1.9
2.3
10.87
11.43
mg/l
0.23
59
289
362
2707
1.47
8.34
1.4
1.3
0.90
1.69
u/ml
1.89
101
781
413
3172
1.45
8.26
2.4
2.1
172.73
219.72
u/l
0.66
399
3028
488
3869
1.42
8.19
4.1
3.4
39.62
55.92
ng/l
0.28
329
2485
1160
10833
1.80
8.19
31.8
15.9
3.91
3.96
mmol/l
7.54
1145
10610
72
346
2.15
8.14
1.8
1.7
0.22
0.24
g/l
0.72
66
333
89
464
1.99
8.10
4.0
3.7
—
—
—
0
0
208
1390
1.59
8.06
1.9
1.4
—
—
—
0
0
445
3484
1.43
7.95
3.6
3.4
2.34
2.35
mmol/l
1.47
411
3217
414
3201
1.43
7.92
3.8
3.5
39.86
55.84
mg/l
1.29
305
2094
73
357
2.11
7.90
1.8
1.7
1.19
1.20
g/l
0.09
68
343
399
3066
1.44
7.89
4.6
3.6
0.00
0.01
estimate
1.54
195
1094
116
672
1.80
7.66
4.0
3.5
7.41
7.42
ph
0.34
100
569
455
3598
1.41
7.61
3.7
3.4
8.52
8.15
mmol/l
0.84
406
3102
417
3258
1.42
7.44
4.6
4.2
8.13
9.49
mg/mmol
0.23
299
2090
171
1113
1.62
7.36
10.1
8.6
-0.27
0.83
mmol/l
2.25
134
927
892
7930
1.42
7.30
6.3
3.3
60.25
46.07
u/l
4.29
862
7585
87
468
1.92
7.25
1.1
1.1
—
—
—
0
0
172
1128
1.61
7.18
10.4
8.6
4.93
5.14
kpa
1.97
163
1087
45
187
2.46
7.15
2.1
2.2
16.42
5.18
umol/l
2.05
30
139
172
1129
1.61
7.15
10.3
8.6
13.33
12.46
kpa
1.27
164
1090
87
471
1.91
7.12
1.4
1.2
—
1.19
—
0
27
105
604
1.80
7.10
1.8
1.7
0.20
0.32
mg/l
2.28
47
303
135
836
1.69
7.05
2.6
2.3
0.55
0.35
e6/l
0.48
130
796
171
1125
1.60
7.04
10.3
8.6
7.41
7.41
ph
0.14
83
621
46
197
2.39
6.86
4.2
4.3
1.96
2.40
mmol/l
0.68
31
127
59
282
2.15
6.80
2.2
3.9
35.17
38.75
mg/l
0.19
52
241
98
561
1.81
6.74
1.1
1.1
—
151.50
titre
—
0
14
1204
11463
1.93
6.70
42.6
17.3
78.54
75.70
umol/l
2.13
1197
11358
22
64
3.48
6.58
3.3
1.3
18.21
26.61
umol/l
0.78
22
59
1198
11402
1.86
6.46
30.5
10.8
26.71
27.12
u/l
0.45
1193
11146
79
429
1.90
6.42
1.3
1.2
—
—
—
0
0
124
770
1.68
6.42
5.7
3.8
1.22
1.23
mmol/l
0.23
118
661
49
224
2.24
6.32
3.3
3.6
—
—
—
0
0
146
951
1.60
6.26
2.6
2.1
0.00
0.02
estimate
0.78
25
217
357
2788
1.39
6.18
3.5
2.7
344.25
339.89
umol/l
0.31
324
2517
26
88
3.00
6.13
4.0
3.9
13.29
12.22
index
0.26
17
63
57
282
2.07
6.04
2.3
3.9
42.53
67.88
mg/l
0.61
50
242
144
945
1.59
5.98
11.2
9.4
116.55
122.55
g/l
2.85
139
925
36
149
2.46
5.82
1.1
1.2
—
—
—
0
0
16
41
3.94
5.72
2.6
4.2
—
—
—
0
0
38
163
2.37
5.70
2.1
1.3
40.48
64.34
mmol/l
4.41
23
136
149
1000
1.55
5.62
11.5
9.1
97.09
95.62
%
5.53
143
969
396
3185
1.35
5.61
3.4
2.7
0.00
0.04
—
6
56
22
72
3.09
5.51
1.1
1.1
—
104.64
—
0
5
405
3278
1.35
5.48
4.2
2.9
0.00
0.10
estimate
1.01
178
954
41
186
2.24
5.42
1.4
1.7
—
—
—
0
0
50
250
2.04
5.19
5.6
3.5
33.77
37.88
umol/l
0.47
43
233
263
2007
1.39
5.12
1.4
1.3
3.28
11.35
u/ml
3.56
99
824
63
345
1.87
5.05
1.3
1.1
—
—
—
0
0
31
129
2.44
4.99
1.3
1.2
—
—
—
0
0
516
4380
1.30
4.85
4.4
3.4
0.01
0.03
estimate
1.16
177
984
126
844
1.55
4.81
1.4
1.3
118.05
216.75
u/ml
2.35
119
790
280
2182
1.36
4.77
1.4
1.3
25.99
25.82
iu/ml
0.01
77
640
8
8
10.05
4.52
1.0
1.0
—
—
—
0
0
31
136
2.31
4.47
3.1
2.4
1.23
0.89
%
1.50
26
92
250
1936
1.36
4.41
3.6
3.6
619.38
461.36
ng/l
0.17
172
1382
58
325
1.82
4.36
1.4
1.2
6.11
2.73
u/ml
—
8
30
18
61
2.98
4.29
2.3
2.6
897.28
969.38
u/ml
0.06
18
61
58
328
1.80
4.24
1.4
1.3
13.11
9.05
u/ml
0.26
14
47
48
256
1.91
4.21
2.2
3.7
1.32
2.39
ratio
1.77
26
143
15
39
3.88
4.20
1.8
1.9
25.80
28.97
%
0.35
15
39
27
116
2.36
4.10
2.5
2.8
—
—
—
0
0
73
448
1.67
4.02
3.9
3.3
1.02
1.02
ratio
0.09
66
419
22
87
2.56
3.98
1.2
1.3
—
—
—
0
0
81
513
1.62
3.95
2.5
2.2
0.00
1.48
estimate
0.51
16
172
14
37
3.81
3.90
1.0
1.4
—
—
—
0
0
87
564
1.58
3.86
2.5
2.2
7004.95
6424.25
u/l
0.04
24
231
329
2710
1.29
3.71
3.5
3.2
1125.22
1103.91
ng/l
0.04
277
2268
48
268
1.82
3.69
3.5
2.4
58.06
62.10
%
0.61
48
260
17
62
2.77
3.59
1.7
1.6
0.91
1.32
nmol/l
0.94
12
46
69
433
1.63
3.52
1.3
1.3
8.01
8.34
u/l
0.09
52
352
13
36
3.64
3.50
1.0
1.0
—
—
—
0
0
17
63
2.72
3.50
4.4
4.2
0.71
0.83
index
0.38
17
63
12
31
3.90
3.49
1.8
2.1
42.00
41.07
g/l
0.19
12
31
10
22
4.57
3.43
2.6
1.8
0.08
0.19
e9/l
—
5
9
28
133
2.13
3.41
3.2
2.6
31.96
32.85
pg
0.41
28
133
37
199
1.89
3.23
1.3
1.2
2.75
5.89
u/ml
1.16
20
87
43
244
1.79
3.18
1.5
1.5
62.88
184.29
pmol/l
1.12
43
238
12
35
3.45
3.11
1.0
1.1
—
—
—
0
0
12
35
3.45
3.11
1.2
1.1
—
—
—
0
0
21
93
2.28
3.04
1.0
1.1
128.19
109.35
pmol/l
0.92
21
93
34
182
1.89
3.03
1.1
1.2
—
—
—
0
0
12
36
3.36
3.02
1.8
2.9
—
—
—
0
0
24
113
2.15
3.01
1.3
1.4
—
—
—
0
0
910
8517
1.24
3.00
4.5
4.3
14.70
14.57
pmol/l
0.81
847
7927
8
17
4.73
2.92
1.0
1.1
—
—
—
0
0
67
440
1.55
2.88
2.0
1.8
—
—
—
0
0
22
102
2.18
2.88
3.6
2.6
1.16
1.19
mmol/l
1.29
22
102
47
752
0.61
2.84
1.3
1.2
—
—
—
0
0
22
103
2.16
2.81
3.6
2.7
106.50
105.27
mmol/l
0.57
22
103
22
103
2.16
2.81
3.6
2.7
3.95
4.05
mmol/l
0.37
22
103
83
1174
0.69
2.81
1.5
1.7
3.30
3.47
mmol/l
0.64
54
825
20
90
2.24
2.81
1.1
1.2
—
—
—
0
0
8
18
4.47
2.79
2.6
1.8
—
—
—
0
0
19
84
2.28
2.78
1.2
1.1
—
—
—
0
0
46
282
1.65
2.64
1.2
1.2
54.86
45.19
u/ml
—
5
25
232
1906
1.27
2.62
3.6
2.8
2.45
2.44
mmol/l
1.12
205
1726
7
15
4.69
2.60
1.1
1.1
—
—
—
0
0
11
36
3.07
2.56
1.1
1.0
—
—
—
0
0
12
42
2.87
2.55
1.9
2.6
—
—
—
0
0
27
144
1.89
2.47
2.1
2.2
—
—
—
0
0
8
21
3.83
2.46
2.5
2.5
—
—
—
0
0
14
57
2.47
2.45
1.6
1.7
85.95
105.53
ng/l
0.38
14
57
112
840
1.37
2.45
3.1
2.3
6.01
6.11
ph
0.61
72
552
16
70
2.30
2.41
1.1
1.2
—
—
—
0
0
25
131
1.93
2.41
1.2
1.1
—
—
—
0
0
7
17
4.13
2.36
2.1
1.4
—
—
—
0
0
120
1551
0.75
2.36
1.7
2.0
3.29
3.51
ratio
1.28
92
1198
90
657
1.40
2.32
2.8
3.0
163.79
169.62
ng/l
0.04
80
591
14
59
2.39
2.29
1.0
1.1
1083.86
1712.93
miu/ml
1.35
14
59
26
141
1.86
2.28
1.2
1.3
—
55.24
—
0
7
22
113
1.96
2.26
1.5
1.3
—
—
nmol/l
—
0
0
46
295
1.58
2.25
5.0
5.9
1.55
1.27
mmol/l
0.61
41
256
33
194
1.72
2.24
3.2
3.1
6.94
8.22
pmol/l
0.52
33
194
101
757
1.36
2.24
2.5
2.3
3.80
8.22
ug/l
4.71
94
685
8
24
3.35
2.18
1.0
1.7
—
—
—
0
0
11
42
2.63
2.14
1.7
1.8
75.82
53.42
ug/l
0.64
11
42
434
4828
0.85
2.11
3.3
2.9
—
—
—
0
0
34
208
1.65
2.02
2.8
4.2
—
—
—
0
0
36
224
1.62
2.01
3.1
2.6
92.77
89.67
%
4.21
36
218
18
90
2.01
2.01
1.4
2.5
—
—
—
0
0
13
57
2.29
1.98
1.2
1.2
141.17
149.05
nmol/l
0.19
13
57
37
565
0.64
1.90
1.1
1.1
1.52
1.54
g/l
0.13
37
565
52
359
1.47
1.86
2.4
2.3
576.74
309.13
ug/l
0.31
47
339
36
229
1.59
1.86
1.9
1.8
—
—
—
0
0
39
253
1.56
1.86
1.7
2.2
0.94
0.90
nmol/l
0.08
32
219
7
23
3.05
1.80
1.3
1.4
—
—
—
0
0
23
132
1.76
1.74
1.6
1.5
18.80
32.86
ng/l
0.90
23
132
20
110
1.83
1.73
1.2
1.4
33.80
33.14
g/l
0.06
15
95
41
274
1.51
1.73
1.2
1.1
—
—
—
0
0
41
274
1.51
1.73
1.2
1.1
—
—
—
0
0
50
350
1.45
1.69
1.8
2.4
—
—
—
0
0
12
55
2.19
1.67
1.5
1.2
110.68
179.78
mmol/24h
3.32
12
55
28
438
0.63
1.64
1.5
1.5
51.44
59.55
ug/l
0.53
20
361
5
14
3.58
1.61
1.4
2.1
—
—
—
0
0
5
14
3.58
1.61
1.0
2.0
—
—
—
0
0
12
56
2.15
1.61
1.1
1.1
221.93
198.86
iu/ml
0.08
12
56
64
473
1.37
1.61
1.3
1.3
199.54
212.89
miu/ml
0.11
35
232
7
26
2.70
1.58
3.1
3.5
4.29
5.53
ug/l
—
7
26
70
527
1.35
1.57
1.9
2.8
22.09
69.81
u/ml
1.36
70
509
10
44
2.28
1.55
1.4
1.5
—
—
—
0
0
76
581
1.33
1.55
7.5
7.0
23.39
24.53
mmol/l
1.51
70
554
30
193
1.57
1.52
1.2
1.3
31.08
35.43
u/l
0.15
25
159
113
914
1.26
1.51
1.2
1.2
—
—
—
0
0
9
37
2.44
1.48
1.0
1.6
64.44
86.01
nmol/24h
—
9
37
22
354
0.61
1.47
1.6
1.5
—
—
—
0
0
22
132
1.68
1.46
1.6
1.3
0.64
0.56
nmol/l
0.43
22
126
9
38
2.38
1.45
1.3
1.2
28.89
27.95
s
—
9
38
30
196
1.54
1.44
1.2
1.2
—
—
—
0
0
16
88
1.83
1.41
1.7
1.3
76.69
75.16
umol/l
0.12
16
88
22
135
1.64
1.36
3.3
3.2
0.86
0.85
nmol/l
0.03
17
109
16
90
1.79
1.33
1.8
1.1
—
—
—
0
0
1207
11881
1.31
1.33
51.0
21.1
91.45
90.70
fl
6.22
1202
11791
22
343
0.64
1.31
1.6
1.4
—
—
—
0
0
6
24
2.51
1.30
3.3
1.5
—
—
—
0
0
9
43
2.10
1.30
2.0
2.2
—
—
—
0
0
1207
11884
1.30
1.30
51.2
21.1
4.43
4.56
e12/l
15.68
1198
11678
1207
11884
1.30
1.30
50.9
21.0
30.30
30.29
pg
0.06
1202
11793
25
161
1.56
1.29
1.4
1.8
—
—
—
0
0
1207
11885
1.30
1.29
52.2
21.5
40.11
41.25
%
2.32
1202
11787
1035
10049
1.16
1.28
5.6
5.2
1.69
1.83
mu/l
4.44
983
9443
1207
11886
1.30
1.28
51.4
21.2
6.87
6.72
e9/l
1.86
1198
11671
1206
11875
1.30
1.27
51.3
21.2
272.77
252.37
e9/l
17.20
1199
11691
9
44
2.05
1.27
3.0
1.3
—
—
—
0
0
22
339
0.64
1.25
1.6
1.4
1.22
1.27
mm
0.21
13
234
6
25
2.41
1.24
1.3
1.1
—
—
—
0
0
9
45
2.01
1.23
1.0
1.7
—
—
—
0
0
5
19
2.64
1.21
1.0
1.8
5.60
4.11
%
—
5
19
5
20
2.51
1.15
1.4
1.2
—
—
—
0
0
133
1131
1.20
1.15
2.6
2.4
12.75
13.25
nmol/l
0.32
122
1036
7
31
2.26
1.10
2.1
2.0
—
—
—
0
0
58
737
0.78
1.10
1.6
1.6
1154.73
1009.77
mu/l
0.38
45
603
11
59
1.87
1.07
1.5
2.9
1924.09
2077.55
ml
0.20
11
53
15
242
0.62
1.07
2.0
1.6
—
—
—
0
0
54
419
1.30
1.06
1.8
1.8
—
—
—
0
0
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
118
1377
0.84
1.01
1.3
1.3
—
—
—
0
0
41
308
1.34
1.01
1.2
1.1
—
—
—
0
0
23
156
1.48
0.99
2.3
1.9
—
1810.00
—
0
8
183
2059
0.87
0.99
3.1
3.0
0.74
0.74
ug/l
0.01
111
1205
178
1574
1.15
0.98
1.6
1.5
—
—
—
0
0
12
198
0.60
0.95
1.2
1.2
—
—
—
0
0
118
1369
0.85
0.95
1.5
1.7
—
—
—
0
0
7
37
1.90
0.94
1.3
1.1
—
—
—
0
0
7
37
1.90
0.94
1.3
1.1
—
—
—
0
0
7
37
1.90
0.94
1.3
1.1
—
—
—
0
0
275
2516
1.12
0.90
4.2
3.5
1.02
1.62
kg/l
0.50
185
1678
33
245
1.36
0.89
2.3
2.3
132.00
131.47
g/l
0.05
24
201
70
576
1.23
0.88
1.9
1.6
294.11
289.59
mu/l
0.06
64
526
57
460
1.25
0.86
2.4
2.8
—
—
—
0
0
6
115
0.52
0.82
2.2
2.2
—
—
—
0
0
11
66
1.67
0.78
1.2
1.2
—
—
—
0
0
15
98
1.54
0.78
1.2
1.1
—
—
—
0
0
94
807
1.18
0.78
2.5
2.4
20.87
18.83
au/ml
0.09
15
105
13
82
1.59
0.78
1.1
1.0
—
—
—
0
0
18
123
1.47
0.77
1.5
1.5
277.23
282.29
mosm/kgh2o
0.33
13
92
1054
10733
0.90
0.77
5.3
4.7
1.48
1.44
mmol/l
2.42
998
10133
26
192
1.36
0.75
1.2
1.1
1.00
132.05
iu/ml
—
7
42
14
91
1.54
0.75
1.1
1.1
—
—
—
0
0
89
765
1.18
0.74
1.5
1.4
19.28
23.91
iu/l
0.80
72
656
35
272
1.29
0.73
1.9
2.6
—
—
—
0
0
14
92
1.53
0.72
1.2
1.3
2308.63
2028.75
e6/l
—
8
55
13
84
1.55
0.72
1.2
1.4
3650.00
25770.63
e6/l
—
7
43
86
740
1.17
0.71
3.8
3.8
4.53
4.56
pmol/l
0.09
77
667
14
93
1.51
0.69
1.1
1.4
—
—
—
0
0
12
77
1.56
0.68
1.7
3.0
1031.58
948.38
mg
0.06
12
77
11
69
1.60
0.68
1.2
1.3
—
—
—
0
0
1002
10213
0.91
0.68
4.7
4.0
1.38
1.29
mmol/l
2.73
939
9573
10
155
0.64
0.66
1.5
1.4
7.52
7.21
mmol/l
—
10
135
8
49
1.64
0.62
1.4
1.9
—
—
—
0
0
1073
10885
0.91
0.59
5.8
5.3
2.62
2.77
mmol/l
6.62
1016
10294
12
82
1.47
0.54
1.0
1.0
1.34
1.07
u/ml
—
6
31
14
99
1.42
0.54
1.0
1.2
48974.89
209275.34
e6/l
—
9
68
43
359
1.20
0.53
3.0
3.7
252.17
315.52
mg/l
0.41
24
166
16
118
1.36
0.50
2.3
2.8
1.39
1.29
g/24h
—
10
77
37
307
1.21
0.49
1.8
1.3
—
—
—
0
0
37
443
0.83
0.49
2.2
2.2
—
—
—
0
0
7
45
1.56
0.49
2.4
1.6
0.59
0.52
e9/l
—
7
45
5
32
1.56
0.42
1.0
1.1
22.94
46.74
iu/ml
—
5
32
1065
10774
0.93
0.42
5.5
4.8
4.59
4.67
mmol/l
1.88
1013
10226
356
3411
1.06
0.41
1.7
1.5
—
—
—
0
0
5
33
1.52
0.41
3.0
2.5
23.78
17.08
umol/l
—
5
33
0
16
0.00
0.41
0.0
1.1
—
72.00
—
0
16
14
105
1.34
0.41
1.4
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
5
35
1.43
0.39
2.0
3.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
138.69
—
0
13
0
19
0.00
0.39
0.0
1.1
—
0.21
—
0
19
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
12
89
1.35
0.38
1.2
1.1
—
—
—
0
0
23
189
1.22
0.36
1.1
1.1
4.63
2.63
eliau/ml
—
6
91
11
82
1.34
0.34
16.5
13.5
0.65
0.62
mmol/l
0.28
11
73
6
47
1.28
0.32
1.0
1.0
—
—
—
0
0
29
249
1.17
0.30
1.6
1.4
0.27
0.38
nmol/l
0.72
21
199
25
213
1.18
0.29
5.8
3.8
22.40
27.69
mg/l
0.49
20
152
10
76
1.32
0.28
1.0
1.0
0.31
0.38
u/ml
—
5
18
28
243
1.16
0.27
2.3
2.4
61.30
106.47
ug/min
0.53
15
153
10
78
1.28
0.24
1.3
1.3
—
—
—
0
0
18
210
0.86
0.22
1.1
1.0
0.59
0.32
u/ml
—
7
70
13
107
1.22
0.21
1.4
1.5
0.93
1.22
promille
—
8
89
0
11
0.00
0.21
0.0
3.6
—
0.19
—
0
11
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
21
241
0.87
0.21
1.1
1.1
2.63
2.86
u/ml
—
8
118
0
12
0.00
0.21
0.0
1.0
—
0.11
—
0
5
11
89
1.24
0.21
1.1
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
0.16
—
0
7
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
48
1.25
0.20
1.2
1.1
—
—
—
0
0
79
744
1.07
0.19
1.4
1.3
50.71
44.77
au/ml
—
8
55
147
1530
0.96
0.18
1.9
1.8
—
—
—
0
0
26
232
1.12
0.18
1.2
1.1
15.68
18.39
au/ml
—
6
71
7
60
1.17
0.17
1.0
1.5
—
77.13
%
—
0
8
17
148
1.15
0.17
2.2
1.6
—
—
—
0
0
17
148
1.15
0.17
2.2
1.6
—
—
—
0
0
17
148
1.15
0.17
2.2
1.6
—
—
—
0
0
17
148
1.15
0.17
2.2
1.6
—
—
—
0
0
12
101
1.19
0.16
1.0
1.1
—
—
—
0
0
12
101
1.19
0.16
3.0
2.7
—
—
—
0
0
54
506
1.07
0.16
1.7
2.0
—
—
—
0
0
131
1263
1.04
0.15
1.5
1.4
—
—
—
0
0
7
86
0.81
0.14
2.6
2.9
49.97
27.91
mg/l
—
7
63
8
98
0.82
0.13
1.1
1.1
34.20
40.59
mg/l
—
8
76
61
580
1.05
0.12
2.1
1.2
0.88
0.89
g/l
0.25
61
580
24
262
0.91
0.12
1.1
1.1
1.06
1.77
u/ml
0.51
13
131
1024
10291
0.97
0.12
5.3
4.6
5.86
5.86
mmol/l
0.03
958
9591
34
317
1.07
0.12
15.8
9.5
—
—
—
0
0
24
221
1.09
0.11
1.2
1.4
24.35
22.03
u/l
0.11
19
183
5
45
1.11
0.09
2.2
2.4
1.46
1.96
ug/l
—
5
38
69
716
0.96
0.09
1.7
1.7
—
—
—
0
0
6
54
1.11
0.09
4.2
2.6
44.83
50.00
umol/l
—
6
49
29
273
1.06
0.08
1.3
1.3
—
—
—
0
0
10
88
1.14
0.08
1.0
1.6
—
—
—
0
0
8
74
1.08
0.07
1.1
1.1
11.00
8.65
mm/h
—
8
74
15
137
1.10
0.07
4.3
2.6
—
—
—
0
0
7
82
0.85
0.07
1.0
1.1
—
0.32
—
0
13
24
255
0.94
0.07
1.2
1.1
0.49
1.39
u/ml
0.72
13
103
24
255
0.94
0.07
1.0
1.5
14.22
25.01
e6/l
0.25
18
191
25
265
0.94
0.07
1.2
1.1
5.50
4.41
u/ml
0.10
14
140
12
132
0.91
0.06
2.3
2.2
—
—
—
0
0
1005
10081
0.99
0.06
6.8
5.8
38.88
38.59
mmol/mol
0.42
951
9585
21
223
0.94
0.06
1.1
1.1
0.96
4.28
u/ml
—
9
97
28
267
1.05
0.05
2.1
1.5
12281.26
10186.93
e6/l
0.20
19
199
465
4626
1.01
0.04
2.0
1.9
1.51
1.37
mmol/l
2.56
389
3985
61
597
1.02
0.03
1.8
2.1
—
—
—
0
0
25
260
0.96
0.03
1.0
1.5
66.16
842.80
e6/l
0.87
19
203
13
122
1.07
0.02
1.0
1.5
—
—
—
0
0
34
331
1.03
0.02
3.4
2.2
4.76
4.23
iu/l
0.14
13
139
337
3384
0.99
0.02
5.0
5.0
2.25
2.28
ug/l
0.04
310
3066
31
304
1.02
0.00
1.2
1.1
1.73
3.01
u/ml
0.42
18
164
64
642
1.00
0.00
1.9
2.0
—
—
—
0
0
65
652
1.00
0.00
1.9
2.1
—
—
—
0
0
65
649
1.00
0.00
1.8
2.1
—
—
—
0
0
12
117
1.03
0.00
1.2
1.7
—
—
—
0
0
20
197
1.02
0.00
1.3
1.2
—
—
—
0
0
24
237
1.01
0.00
1.0
1.5
—
—
—
0
0
89
887
1.00
0.00
1.3
1.2
116.99
145.58
u/ml
0.32
33
361
69
687
1.00
0.00
1.1
1.1
—
—
—
0
0
65
645
1.01
0.00
1.9
2.1
—
—
—
0
0
5
59
0.85
0.00
1.0
1.1
—
—
—
0
0
5
59
0.85
0.00
1.2
3.2
15.80
16.43
%
—
5
59
0
6
0.00
-0.00
0.0
1.0
—
0.96
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
0.16
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.86
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
-0.00
1.2
1.5
156.61
152.26
pmol/l
—
9
91
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
2.72
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.0
—
107.00
—
0
5
7
73
0.96
-0.00
1.7
1.3
26.50
31.39
nmol/l
—
7
60
8
79
1.01
-0.00
1.1
1.4
9.53
6.11
ug/l
—
8
70
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.2
—
388.67
—
0
6
0
8
0.00
-0.00
0.0
2.6
—
195.25
—
0
8
0
8
0.00
-0.00
0.0
1.6
—
365.13
—
0
8
0
8
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint ULCERENTER and mortality.

Females

Parameter HR [95% CI] p-value
ULCERENTER 1.635 [1.44, 1.86] < 0.001
Birth year 0.996 [0.99, 1.0] 0.321

During the follow-up period (1.1.1998 — 31.12.2019), 499 out of 3272 females with ULCERENTER died.

Males

Parameter HR [95% CI] p-value
ULCERENTER 1.552 [1.39, 1.74] < 0.001
Birth year 0.987 [0.98, 1.0] 0.017

During the follow-up period (1.1.1998 — 31.12.2019), 724 out of 3513 males with ULCERENTER died.

Mortality risk

Mortality risk for people of age

years, who have ULCERENTER.

N-year risk Females Males
1 0.182% 0.27%
5 0.994% 1.839%
10 2.632% 4.43%
15 5.101% 8.5%
20 8.421% 14.2%

Relationships between endpoints

Index endpoint: ULCERENTER – Ulcerative enterocolitis

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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