Neuroendocrine tumor and carcinoma of pancreas

C3_PANCREAS_NEUROENDOCRINE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C25
  • Cancer registry: Morphology ICD-O-3 8240|8246|8249
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

270

4. Check minimum number of events

None

270

5. Include endpoints

None

270

6. Filter based on genotype QC (FinnGen only)

234

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 234 107 127
Unadjusted period prevalence (%) 0.05 0.04 0.06
Median age at first event (years) 62.96 60.45 65.08

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
245
Matched controls
2450
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
326.4
317.5
151
12
130
Kela drug reimbursment
Malignant tumour
+∞
166.2
140
*
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
98.5
151.1
80
12
WX302
NOMESCO Finland
Thoracal epidural anesthesy
55.0
132.9
79
21
C25.4
ICD-10 Finland
Malignant neoplasm: Endocrine pancreas
+∞
112.4
99
*
JN4AD
NOMESCO Finland
Body CT examination
18.6
100.9
96
82
H01CB03
ATC
lanreotide; parenteral
1153.1
86.1
79
*
8240/3-C25.9
ICD-O-3
Neuroendocrine tumor, NOS, of pancreas, NOS
+∞
82.0
74
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
31.3
81.4
56
23
JN4CD
NOMESCO Finland
Very extensive body CT
52.6
80.1
47
11
H02AB02
ATC
dexamethasone; systemic
51.3
77.9
46
11
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
+∞
77.3
70
*
JN4BD
NOMESCO Finland
Extensive body CT
18.1
75.6
68
51
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
45.7
74.2
45
12
A03FA01
ATC
metoclopramide; systemic, rectal
10.6
74.0
111
177
A04AA02
ATC
granisetron; systemic, transdermal
911.8
71.9
67
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
32.9
71.6
48
18
L01BC06
ATC
capecitabine; oral
+∞
71.4
65
*
L01AX03
ATC
temozolomide; systemic
+∞
69.1
63
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
66.8
61
*
8249/3-C25.9
ICD-O-3
Neuroendocrine tumor, grade 2 of pancreas, NOS
+∞
65.6
60
*
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
143.6
62.3
64
6
JLC10
NOMESCO Finland
Distal pancreatectomy
+∞
62.2
57
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
62.2
57
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
31.5
62.1
42
16
A04AA01
ATC
ondansetron; systemic, rectal
21.6
61.8
49
28
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
57.6
53
*
JLC11
NOMESCO Finland
Laparoscopic distal pancreatectomy
+∞
54.2
50
*
D76
ICPC
Malignant neoplasm pancreas
+∞
53.1
49
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
14.1
52.7
53
47
D13.7
ICD-10 Finland
Benign neoplasm: Endocrine pancreas
+∞
50.8
47
*
JN3AD
NOMESCO Finland
Abdominal CT examination
8.0
50.8
89
163
TPH07
NOMESCO Finland
Cathetrisation of artery
8.5
49.0
78
128
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
48.6
45
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
8.9
48.4
72
109
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
9.2
47.1
67
96
C25.2
ICD-10 Finland
Malignant neoplasm: Tail of pancreas
+∞
45.2
42
*
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
+∞
45.2
42
*
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
514.3
44.7
43
*
H01CB02
ATC
octreotide; parenteral
259.4
43.4
43
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
10.0
41.4
53
66
XX7JT
NOMESCO Finland
Somatostatin isotope ablative therapy
+∞
40.8
38
*
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
237.8
40.1
40
*
XX3DW
NOMESCO Finland
Time consuming IT work
11.5
39.8
45
47
Z51.5
ICD-10 Finland
Palliative care
11.6
37.6
42
43
WZC30
NOMESCO Finland
Teaching
6.1
36.4
81
183
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
51.8
36.4
43
10
E34.0
ICD-10 Finland
Carcinoid syndrome
+∞
34.2
32
*
158
Kela drug reimbursment
Everolimus
+∞
30.9
29
*
JLC30
NOMESCO Finland
Pancreatoduodenectomy
+∞
30.9
29
*
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
95.0
30.6
33
*
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
328.9
29.4
29
*
ZXE20
NOMESCO Finland
More than three and less than five hours
5.7
29.3
67
153
WZC00
NOMESCO Finland
Treatment plan or consultation
4.4
29.0
122
453
N02AA05
ATC
oxycodone; systemic
5.2
28.9
76
196
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
27.6
26
*
197
Kela drug reimbursment
Sunitinib
+∞
27.6
26
*
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
289.5
26.2
26
*
XX9AN
NOMESCO Finland
Complementary isotope examination or additional picture
289.5
26.2
26
*
B01AB05
ATC
enoxaparin; parenteral
4.0
25.6
117
453
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
25.5
24
*
JMA10
NOMESCO Finland
Transabdominal total splenectomy
277.1
25.2
25
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.2
24.8
61
147
8249/3-C25.2
ICD-O-3
Neuroendocrine tumor, grade 2 of tail of pancreas
+∞
24.4
23
*
340
Kela drug reimbursment
Everolimus
+∞
23.3
22
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.9
23.3
100
367
B01AB04
ATC
dalteparin; parenteral
8.7
23.1
31
40
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
50.3
22.9
27
6
A10AE04
ATC
insulin glargine; parenteral
4.9
22.6
59
149
C25.1
ICD-10 Finland
Malignant neoplasm: Body of pancreas
+∞
21.1
20
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
21.1
20
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
228.6
20.9
21
*
A10AB05
ATC
insulin aspart; parenteral
5.4
20.6
46
101
JLC00
NOMESCO Finland
Excision of lesion of pancreas
+∞
20.1
19
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
20.1
19
*
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
216.8
19.9
20
*
JMA11
NOMESCO Finland
Laparoscopic total splenectomy
216.8
19.9
20
*
103
Kela drug reimbursment
Diabetes, insulin-treated
3.4
19.3
113
495
JAH01
NOMESCO Finland
Laparoscopy
7.5
19.1
29
43
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.3
19.1
122
563
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.4
19.0
107
457
JL1AT
NOMESCO Finland
Biopsy of pancreas with ultrasound guidance
+∞
19.0
18
*
A79
ICPC
Malignancy NOS
+∞
19.0
18
*
C25.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of pancreas
+∞
19.0
18
*
8246/3-C25.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of pancreas, NOS
+∞
19.0
18
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
40.0
17.9
22
6
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
193.4
17.8
18
*
WX402
NOMESCO Finland
General anaesthesia
3.5
17.3
78
288
JN4SR
NOMESCO Finland
Very extensive PET-CT of receptors in whole body
+∞
16.9
16
*
L01XE10
ATC
[U] everolimus
+∞
16.9
16
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
181.9
16.7
17
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
16.1
68
240
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
15.8
15
*
322
Kela drug reimbursment
Sunitinib
+∞
15.8
15
*
8240/3-C25.2
ICD-O-3
Neuroendocrine tumor, NOS, of tail of pancreas
+∞
15.8
15
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
91.0
15.8
17
*
WF002
NOMESCO Finland
Radical radiotherapy
170.4
15.7
16
*
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
170.4
15.7
16
*
B01AB10
ATC
tinzaparin; parenteral
4.5
15.6
42
107
WVA30, ,
SPAT
5.1
15.0
34
75
115
Kela drug reimbursment
Breast cancer
+∞
14.7
14
*
8249/3-C25.1
ICD-O-3
Neuroendocrine tumor, grade 2 of body of pancreas
+∞
14.7
14
*
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
159.1
14.6
15
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
14.6
149
857
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
14.6
14.6
24
18
JAH00
NOMESCO Finland
Laparotomy
13.2
13.9
24
20
L01EG02
ATC
everolimus; oral
+∞
13.7
13
*
E16.10
ICD-10 Finland
Hyperinsulinism
+∞
13.7
13
*
T73
ICPC
Neoplasm endocrine other/unspecified
+∞
13.7
13
*
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
27.6
13.6
18
7
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
13.6
100
481
ZXE10
NOMESCO Finland
More than one and less than three hours
2.8
13.5
108
541
T90
ICPC
Diabetes non-insulin dependent
2.8
13.3
96
455
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
53.0
13.0
15
*
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
34.1
12.7
16
5
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
21.5
12.7
18
9
L01CB01
ATC
etoposide; systemic
+∞
12.6
12
*
L01XE04
ATC
[U] sunitinib
+∞
12.6
12
*
L01EX01
ATC
sunitinib; oral
+∞
12.6
12
*
JN7AN
NOMESCO Finland
Somatostatin receptor isotope imaging
136.7
12.6
13
*
R4190
NOMESCO Finland
Nutritional therapy
10.5
12.6
24
25
J01MA12
ATC
levofloxacin; systemic
3.1
12.5
63
244
UJK02
NOMESCO Finland
ERCP
13.4
12.4
21
17
A10BA02
ATC
metformin; oral
2.6
12.1
105
543
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
49.2
12.0
14
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.8
11.8
40
120
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.0
11.8
63
252
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.7
11.8
23
44
XX2RW, ,
NOMESCO Finland
24.3
11.7
16
7
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
24.3
11.7
16
7
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
68.3
11.7
13
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
11.5
11
*
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
36.9
11.4
14
*
Z31.5
ICD-10 Finland
Genetic counselling
5.7
11.3
22
42
JKA20
NOMESCO Finland
Cholecystectomy
11.4
11.0
20
19
ZXE30
NOMESCO Finland
More than five and less than seven hours
9.2
10.8
22
26
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
10.7
70
311
E21.0
ICD-10 Finland
Primary hyperparathyroidism
9.5
10.5
21
24
L03AA13
ATC
pegfilgrastim; parenteral
114.7
10.5
11
*
106
Kela drug reimbursment
Hypoparathyroidism
114.7
10.5
11
*
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
114.7
10.5
11
*
JJB10
NOMESCO Finland
Atypcal resection of liver
+∞
10.5
10
*
BBA50
NOMESCO Finland
Total parathyroidectomy
+∞
10.5
10
*
8249/3-C25.0
ICD-O-3
Neuroendocrine tumor, grade 2 of head of pancreas
+∞
10.5
10
*
116
Kela drug reimbursment
Prostate cancer
+∞
10.5
10
*
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
19.9
10.4
15
8
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.5
10.3
40
131
A11CC03
ATC
alfacalcidol; systemic
10.7
10.2
19
19
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.9
10.2
32
91
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
17.6
10.0
15
9
ZX120
NOMESCO Finland
Intravenous
4.3
9.9
27
69
A06AH03
ATC
naloxegol; oral
57.3
9.7
11
*
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
103.9
9.5
10
*
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
22.8
9.5
13
6
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
22.8
9.5
13
6
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
9.4
9
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
9.4
9
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
9.2
62
277
WX892
NOMESCO Finland
Monitored bed care
3.7
9.1
30
88
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
25.1
9.0
12
5
K83.0
ICD-10 Finland
Cholangitis
25.1
9.0
12
5
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
13.2
9.0
15
12
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
7.7
8.9
20
28
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.4
8.9
86
455
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
17.1
8.6
13
8
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
7.8
8.6
19
26
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
93.1
8.5
9
*
ZXF10
NOMESCO Finland
Interruption caused by technical failure of equipment
93.1
8.5
9
*
K86.8
ICD-10 Finland
Other specified diseases of pancreas
93.1
8.5
9
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
9.0
8.5
17
20
Z3226
NOMESCO Finland
Physiotherapist
2.7
8.4
53
229
JL2AT
NOMESCO Finland
Cytology of pancreas with ultrasound guidance
+∞
8.4
8
*
JN4DD
NOMESCO Finland
Scout CT scan of torso
+∞
8.4
8
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
8.4
8
*
A04AD12
ATC
aprepitant; systemic
+∞
8.4
8
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
8.4
8
*
C17.9
ICD-10 Finland
Malignant neoplasm: Small intestine, unspecified
+∞
8.4
8
*
L02BG04
ATC
letrozole; oral
17.9
8.2
12
7
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
22.9
8.1
11
5
OAB50, ,
SPAT
3.2
8.1
34
117
ZXD10
NOMESCO Finland
Scheduled procedure
2.2
8.0
100
584
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.1
8.0
23
61
N02AX02
ATC
tramadol; systemic, rectal
2.2
8.0
122
772
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
13.6
8.0
13
10
SPAT1262
SPAT
Handing over of treatment supplies
2.5
7.9
58
269
WW500
NOMESCO Finland
Blood transfusion
11.3
7.9
14
13
ZXC96
NOMESCO Finland
Robot assisted procedure
46.5
7.8
9
*
E21.2
ICD-10 Finland
Other hyperparathyroidism
46.5
7.8
9
*
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
19.1
7.7
11
6
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
9.3
7.7
15
17
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.1
7.4
118
753
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
7.3
7
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
7.3
7
*
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
+∞
7.3
7
*
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
+∞
7.3
7
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
7.3
7
*
JJ6LT
NOMESCO Finland
Coagulation of focal hepatic lesion under ultrasound guidance
+∞
7.3
7
*
JLC40
NOMESCO Finland
Total pancreatoduodenectomy
+∞
7.3
7
*
D44.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Endocrine gland, unspecified
+∞
7.3
7
*
8240/3-C25.0
ICD-O-3
Neuroendocrine tumor, NOS, of head of pancreas
+∞
7.3
7
*
Y77
ICPC
Malignant neoplasm prostate
+∞
7.3
7
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
7.3
7
*
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
+∞
7.3
7
*
C25
ICD-10 Finland
Malignant neoplasm of pancreas
+∞
7.3
7
*
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.3
7.2
19
47
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
31.0
7.2
9
*
R4110
NOMESCO Finland
Physiotherapy
2.2
7.2
74
398
T89
ICPC
Diabetes insulin dependent
4.1
7.1
20
52
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
7.0
84
478
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
14.3
7.0
11
8
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
8.7
6.9
14
17
JN1AD
NOMESCO Finland
CT examination of upper part of abdomen
23.3
6.7
9
*
M05BX04
ATC
denosumab; parenteral
4.0
6.7
19
50
ZXE40
NOMESCO Finland
More than seven and less than nine hours
10.4
6.6
12
12
A50
ICPC
General and Unspecified, Medication/prescr/renewal
4.3
6.5
17
42
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
71.6
6.5
7
*
E22.1
ICD-10 Finland
Hyperprolactinaemia
71.6
6.5
7
*
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
14.8
6.5
10
7
K86.2
ICD-10 Finland
Cyst of pancreas
9.6
6.4
12
13
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.6
6.3
17
32
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
6.3
6
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
E89.1
ICD-10 Finland
Postprocedural hypoinsulinaemia
+∞
6.3
6
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
6.3
6
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
6.3
6
*
8246/3-C25.2
ICD-O-3
Neuroendocrine carcinoma, NOS, of tail of pancreas
+∞
6.3
6
*
D77
ICPC
Malignant digestive neopl other/NOS
+∞
6.3
6
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
6.3
6
*
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
+∞
6.3
6
*
V03AH01
ATC
diazoxide; systemic
+∞
6.3
6
*
JN7SN
NOMESCO Finland
Somatostatin receptor SPECT
+∞
6.3
6
*
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
27.4
6.3
8
*
JFB00
NOMESCO Finland
Partial resection of small intestine
27.4
6.3
8
*
L02AE02
ATC
leuprorelin; implant, parenteral
27.4
6.3
8
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
6.2
35
142
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
6.1
45
208
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.6
6.0
13
18

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
204
9
1324.79
250.14
10.1
2.7
36.93
3.84
nmol/l
—
204
9
112
50
40.42
163.14
1.6
1.2
—
—
—
0
0
140
117
26.59
153.95
3.8
1.4
6.88
2.58
ug/l
1.52
114
82
78
12
94.89
146.64
4.6
1.3
24.21
13.67
ug/l
1.90
78
12
96
54
28.59
125.79
1.9
1.3
197.73
331.92
ug/g
3.63
82
32
80
50
23.27
98.70
3.5
1.7
569.31
11.40
u/ml
0.55
72
35
186
679
8.22
52.37
5.0
2.3
133.92
62.79
u/l
0.89
181
635
200
871
8.06
43.72
10.8
3.6
34.70
36.08
g/l
3.15
195
814
209
996
8.48
39.84
11.9
13.6
1.13
1.27
inr
5.59
180
819
204
1028
6.88
34.08
14.1
6.1
1.20
1.21
mmol/l
1.60
178
898
190
909
5.86
33.59
12.1
5.6
1.20
1.21
mmol/l
1.03
185
828
90
244
5.25
32.58
4.3
2.1
7.71
6.54
umol/l
0.23
81
214
80
196
5.58
32.58
4.4
2.0
145.90
31.09
u/l
1.20
73
157
180
887
4.88
28.90
3.7
2.4
—
—
estimate
—
0
0
140
584
4.26
28.09
8.4
3.4
7.40
7.40
ph
0.09
120
416
70
176
5.17
27.26
1.6
1.1
—
—
—
0
0
128
528
3.98
25.51
6.3
4.0
—
—
—
0
0
91
297
4.28
25.25
8.2
6.3
104.96
104.35
mmol/l
0.56
91
297
139
620
3.87
24.39
3.0
2.0
—
—
—
0
0
192
1121
4.29
21.39
22.1
6.1
4.29
4.23
e9/l
0.11
178
966
135
668
3.27
18.69
11.1
2.0
2.36
2.36
mmol/l
0.09
128
574
107
469
3.28
18.05
2.7
2.0
—
—
—
0
0
26
15
19.22
17.36
2.4
1.5
43.88
23.31
ng/l
0.67
26
15
24
11
24.02
17.23
1.0
1.2
—
—
—
0
0
128
646
3.06
16.58
9.9
5.0
—
—
—
0
0
69
245
3.53
16.15
9.1
7.2
1.25
1.01
mmol/l
0.19
62
203
70
251
3.50
16.13
9.0
7.1
7.42
7.41
ph
0.08
40
144
69
250
3.45
15.59
9.0
7.1
14.50
11.63
kpa
3.69
69
242
69
250
3.45
15.59
9.1
7.1
5.35
5.11
kpa
1.59
69
241
26
43
6.65
15.46
2.8
2.1
4.70
5.35
mmol/24h
0.33
26
38
124
643
2.88
14.85
2.7
1.6
—
—
—
0
0
51
158
3.81
14.52
6.0
4.2
62.47
86.41
ng/l
1.71
41
133
167
1049
2.86
13.31
10.4
5.1
0.04
0.04
e9/l
0.02
144
889
166
1043
2.83
13.16
10.5
5.1
0.62
0.59
e9/l
0.67
144
882
169
1075
2.84
13.02
10.6
5.3
0.21
0.20
e9/l
0.06
147
929
167
1060
2.81
12.85
10.7
5.1
1.94
1.86
e9/l
0.40
146
920
69
285
2.98
12.23
2.7
2.3
19.89
23.79
%
1.62
64
261
72
305
2.93
12.19
2.8
2.3
2.44
2.29
g/l
1.29
66
278
75
332
2.81
11.65
3.0
2.3
11.77
13.73
umol/l
1.43
68
307
108
579
2.55
11.36
15.9
4.4
—
—
—
0
0
147
913
2.53
11.21
24.4
9.3
0.00
0.00
e9/l
0.95
127
732
42
135
3.55
11.20
10.4
5.5
25.38
24.64
mmol/l
0.67
42
130
82
390
2.66
10.99
6.5
1.9
2.47
2.44
mmol/l
1.41
75
341
39
126
3.49
10.29
7.9
3.7
—
—
—
0
0
68
306
2.69
10.07
2.3
1.9
—
—
—
0
0
20
23
9.36
10.00
2.1
1.8
586.02
163.67
u/ml
0.31
20
23
26
68
4.16
9.23
3.1
1.6
1.36
1.97
ug/l
0.23
21
59
112
658
2.29
9.13
3.5
3.1
13.52
61.69
e6/l
1.89
85
488
98
561
2.24
8.34
3.3
2.9
0.23
0.37
e6/l
0.61
69
391
41
163
2.82
7.57
3.5
3.5
124.47
223.90
ng/l
1.39
34
153
44
183
2.71
7.46
8.2
8.2
—
—
—
0
0
117
744
2.10
7.40
3.8
3.7
64.83
102.57
e6/l
0.47
86
509
113
716
2.07
7.16
3.8
3.2
792.77
1102.07
ng/l
0.59
102
591
191
1479
2.32
7.03
6.1
3.2
79.05
46.85
u/l
1.48
186
1389
90
529
2.11
6.92
1.4
1.3
—
—
—
0
0
18
45
4.24
6.75
2.8
3.1
48.01
11.10
pmol/l
0.72
18
45
35
137
2.81
6.63
4.5
3.0
—
—
—
0
0
16
26
6.50
6.59
2.1
1.5
0.15
0.20
nmol/l
1.20
11
19
16
29
5.83
6.11
2.4
1.4
—
—
nmol/l
—
0
0
120
838
1.85
5.24
3.5
3.4
6.87
7.82
mmol/l
1.72
101
709
8
6
13.72
5.11
1.3
1.5
1666.75
61.83
nmol/24h
—
8
6
56
306
2.08
5.04
1.4
1.2
—
—
—
0
0
117
820
1.82
4.98
4.1
4.3
9.02
7.43
mg/mmol
0.20
81
515
114
801
1.79
4.75
3.5
3.6
43.69
48.42
mg/l
0.12
85
514
14
32
4.58
4.51
5.9
2.2
—
—
—
0
0
80
512
1.84
4.49
3.0
2.1
3.10
2.78
mg/l
0.41
69
430
74
466
1.84
4.36
4.2
3.9
—
—
—
0
0
10
16
6.46
4.34
1.2
1.2
—
—
—
0
0
117
854
1.71
4.09
4.2
3.5
0.00
0.02
estimate
0.50
41
177
56
329
1.91
4.06
2.5
3.0
1.69
2.37
e6/l
0.38
19
151
231
2082
2.92
3.99
37.6
13.2
36.71
23.69
mg/l
6.38
221
1662
89
608
1.73
3.92
4.0
3.6
0.00
0.00
estimate
-0.00
39
198
122
908
1.68
3.91
4.8
3.7
38.52
39.77
ng/l
0.03
101
669
32
159
2.16
3.65
3.2
4.4
0.09
0.00
%
0.47
11
30
30
148
2.17
3.49
2.8
4.0
0.27
0.33
%
0.14
11
36
31
158
2.10
3.32
3.2
3.9
0.55
0.54
%
0.01
11
39
87
614
1.65
3.30
4.1
3.1
0.00
0.00
estimate
-0.00
37
166
198
1724
1.77
3.13
44.0
16.2
14.46
13.48
%
11.67
198
1700
82
579
1.63
3.07
3.0
3.1
—
—
—
0
0
137
1093
1.57
3.05
4.2
3.6
0.00
0.00
estimate
-0.00
43
211
9
21
4.41
3.02
1.4
3.5
1.02
0.93
%
—
9
14
39
225
1.87
2.97
1.3
1.2
—
—
—
0
0
71
488
1.64
2.94
1.8
1.7
1.48
1.07
mg/l
1.00
57
383
138
1109
1.56
2.93
4.1
3.7
0.00
8.10
estimate
0.50
44
216
139
1119
1.56
2.93
4.2
3.7
0.00
0.02
estimate
0.50
40
201
16
67
2.49
2.69
2.4
1.7
—
—
—
0
0
14
56
2.59
2.58
16.7
4.8
1.50
1.36
mmol/l
0.22
14
51
20
95
2.20
2.57
12.0
3.4
0.92
0.91
%
0.06
20
89
28
152
1.95
2.55
3.4
4.0
0.00
0.06
%
—
8
33
9
26
3.55
2.50
3.0
2.8
3.89
4.41
e9/l
—
9
26
32
185
1.84
2.43
2.1
2.6
68.18
64.75
e9/l
0.25
24
138
20
98
2.13
2.39
1.5
1.2
—
—
—
0
0
10
35
2.93
2.23
1.0
1.1
—
—
—
0
0
5
10
5.08
2.08
1.4
1.3
—
—
—
0
0
33
203
1.72
2.05
3.2
2.8
4.54
4.36
kpa
0.18
33
195
15
70
2.22
2.03
2.1
1.5
44.53
38.39
u/ml
0.08
15
65
6
16
3.82
1.94
1.0
1.1
160.83
106.25
pmol/l
—
6
16
38
248
1.63
1.91
3.4
3.1
7.38
7.39
ph
0.04
23
149
63
464
1.48
1.86
1.7
1.8
449.69
432.42
pmol/l
0.13
52
385
37
243
1.62
1.82
3.1
3.1
5.70
5.78
kpa
0.29
37
235
39
260
1.59
1.80
1.6
1.5
—
—
—
0
0
36
236
1.62
1.78
1.9
1.7
—
—
—
0
0
9
36
2.56
1.76
3.3
2.4
56.22
58.67
%
—
9
36
23
135
1.78
1.69
2.3
2.4
0.87
1.27
%
1.82
23
135
123
1036
1.38
1.69
2.2
2.0
86.56
96.91
pmol/l
1.81
69
522
36
240
1.59
1.67
3.1
3.0
1.70
1.98
mmol/l
0.13
30
199
5
14
3.62
1.62
5.2
2.6
—
—
—
0
0
33
220
1.58
1.54
1.6
1.5
—
—
—
0
0
22
133
1.72
1.48
2.3
2.4
0.65
0.61
%
0.31
22
133
6
22
2.77
1.44
1.5
2.5
29.17
33.77
pg
—
6
22
25
159
1.64
1.41
3.4
2.6
122.88
131.82
g/l
1.09
25
153
7
29
2.45
1.40
1.3
2.1
—
—
—
0
0
50
372
1.43
1.40
1.8
1.7
1331.54
1137.27
nmol/l
0.59
41
283
113
963
1.32
1.35
3.7
2.9
100.39
120.10
ug/l
0.96
105
898
65
511
1.37
1.33
4.0
3.9
1.02
1.02
kg/l
0.99
49
341
5
18
2.81
1.29
2.2
1.8
9.48
8.60
mmol/l
—
5
18
8
35
2.33
1.28
1.1
1.2
—
—
—
0
0
7
141
0.48
1.25
1.1
1.2
99.74
352.09
u/ml
—
7
129
6
25
2.43
1.25
1.5
2.3
—
—
—
0
0
18
109
1.70
1.22
6.5
4.0
—
—
—
0
0
37
267
1.45
1.22
1.5
1.5
—
—
—
0
0
12
64
1.92
1.20
1.0
1.1
—
110.00
—
0
6
5
21
2.41
1.09
26.8
2.1
9.72
8.21
mmol/l
—
5
16
11
191
0.56
1.09
1.1
1.4
—
—
—
0
0
222
2118
1.51
1.09
8.3
5.3
6.77
6.00
mmol/l
7.88
215
1926
23
154
1.54
1.08
1.1
1.2
—
—
—
0
0
227
2177
1.58
1.07
35.0
12.4
—
—
—
0
0
7
33
2.15
1.06
1.0
1.3
—
—
—
0
0
103
892
1.27
1.02
3.8
3.2
6.12
6.17
ph
0.19
68
525
80
672
1.28
1.02
1.8
1.6
18.10
20.82
nmol/l
1.06
75
565
55
439
1.33
1.01
3.8
3.8
115.44
426.02
ng/l
1.59
41
348
14
85
1.69
0.96
6.5
4.6
24.96
25.23
mmol/l
0.11
14
77
209
1982
1.37
0.96
6.2
5.3
1.97
1.95
mu/l
0.08
194
1813
75
874
0.80
0.88
3.4
3.5
—
—
—
0
0
69
581
1.26
0.85
2.3
2.4
359.12
354.07
umol/l
0.10
57
503
12
189
0.62
0.85
1.1
1.5
—
—
—
0
0
8
45
1.80
0.85
1.0
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
10
59
1.72
0.77
2.8
2.6
1.59
1.56
mg/l
—
10
51
6
34
1.78
0.77
1.7
2.7
1.18
1.19
mmol/l
—
6
34
5
24
2.11
0.75
1.2
1.3
—
—
—
0
0
5
25
2.02
0.73
1.6
2.0
10.00
10.64
mmol/l
—
5
25
9
58
1.57
0.70
3.8
3.9
—
—
—
0
0
10
61
1.67
0.69
1.0
1.2
—
—
—
0
0
5
28
1.80
0.66
1.2
1.6
—
—
—
0
0
5
28
1.80
0.66
1.2
1.6
—
—
—
0
0
5
28
1.80
0.66
1.2
1.6
—
—
—
0
0
5
28
1.80
0.66
1.2
1.6
—
—
—
0
0
10
62
1.64
0.66
2.0
1.8
2.44
5.25
iu/l
—
5
28
174
1640
1.21
0.66
5.8
4.3
14.48
14.82
pmol/l
1.02
168
1489
22
165
1.37
0.63
1.8
2.7
6.00
5.96
ph
0.07
16
107
5
30
1.68
0.62
1.8
1.7
-0.90
0.98
mmol/l
—
5
30
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
6
36
1.68
0.57
1.7
2.6
4.07
4.09
mmol/l
—
6
36
6
36
1.68
0.57
1.7
2.6
104.00
105.69
mmol/l
—
6
36
31
379
0.79
0.55
1.2
1.3
2.30
8.53
u/ml
1.76
15
138
17
222
0.75
0.50
1.5
1.5
—
—
—
0
0
25
201
1.27
0.47
2.1
2.4
5.62
8.90
ug/l
0.67
25
177
32
268
1.22
0.43
3.4
2.4
3.39
4.37
e9/l
2.23
27
223
6
95
0.62
0.43
1.3
1.9
—
—
—
0
0
10
137
0.72
0.40
1.3
1.8
—
—
—
0
0
17
133
1.30
0.40
2.5
1.3
—
—
—
0
0
9
122
0.73
0.36
1.0
1.1
—
—
—
0
0
16
128
1.27
0.33
1.1
1.5
—
—
—
0
0
10
75
1.35
0.30
1.1
1.2
1.54
1.51
g/l
—
10
75
37
415
0.87
0.28
1.1
1.3
15.69
33.79
iu/ml
2.14
11
121
53
483
1.12
0.28
1.6
1.3
2.21
1.72
u/ml
0.15
17
146
5
72
0.69
0.26
1.0
1.5
—
—
—
0
0
5
72
0.69
0.26
1.0
1.4
—
—
—
0
0
5
72
0.69
0.26
1.0
1.4
—
—
—
0
0
10
78
1.29
0.24
1.1
1.2
0.75
0.91
g/l
—
10
78
6
85
0.70
0.24
8.2
8.4
—
—
—
0
0
5
41
1.22
0.22
1.2
1.2
—
—
—
0
0
93
977
0.92
0.22
2.2
2.0
1.38
1.32
mmol/l
0.19
82
817
12
145
0.82
0.21
1.9
1.3
79.80
138.40
u/ml
—
5
60
0
10
0.00
0.21
0.0
1.3
—
208.86
—
0
10
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
59.75
—
0
8
212
2152
0.89
0.21
5.4
5.4
1.36
1.44
mmol/l
1.88
200
1987
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
14
165
0.84
0.20
1.8
2.5
—
11.72
—
0
9
5
70
0.71
0.17
1.0
1.5
—
—
—
0
0
19
168
1.14
0.16
1.4
1.2
—
—
—
0
0
10
119
0.83
0.15
1.3
1.5
0.07
0.38
mg/l
—
5
49
213
2156
0.91
0.15
5.6
5.5
4.33
4.56
mmol/l
2.59
200
2003
7
90
0.77
0.14
1.1
1.3
—
—
—
0
0
94
908
1.06
0.13
5.4
4.1
2.09
1.87
ug/l
0.43
81
819
50
528
0.93
0.13
3.3
2.7
0.79
0.74
ug/l
0.19
33
322
9
107
0.84
0.13
2.2
2.4
—
—
—
0
0
27
292
0.92
0.12
1.2
1.3
297.14
564.80
titre
—
7
75
217
2191
0.92
0.12
6.0
6.3
2.51
2.67
mmol/l
1.78
201
2028
179
1764
1.05
0.11
45.8
17.2
330.46
333.11
g/l
3.07
179
1756
13
144
0.90
0.08
1.0
1.3
—
30.71
—
0
12
7
67
1.05
0.08
1.3
1.1
—
—
—
0
0
41
424
0.96
0.05
1.5
1.3
2.55
2.67
g/l
0.15
25
255
207
2057
1.04
0.05
4.7
4.6
1.43
1.28
mmol/l
1.53
194
1879
22
228
0.96
0.02
1.3
1.5
—
—
—
0
0
10
99
1.01
0.00
1.5
1.9
—
—
—
0
0
30
305
0.98
0.00
1.8
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
20.55
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
83.20
—
0
5
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
11.11
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.3
—
6.70
—
0
6
5
52
0.96
-0.00
1.4
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_PANCREAS_NEUROENDOCRINE – Neuroendocrine tumor and carcinoma of pancreas

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).