Maternal care for cervical incompetence

O15_MATERN_CARE_CERVICAL_INCOMPETENCE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O34.3
  • Hospital discharge: ICD-9 6545|6546
  • Hospital discharge: ICD-8 63494
  • Cause of death: ICD-10 O34.3
  • Cause of death: ICD-9 6545|6546
  • Cause of death: ICD-8 63494

2 out of 7 registries used, show all original rules.

1642

4. Check minimum number of events

None

1642

5. Include endpoints

None

1642

6. Filter based on genotype QC (FinnGen only)

1479

Control definitions (FinnGen only)

Control exclude
O15_MATERN_CARE_PELVIC_ABNORM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF6v3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10979 10979 -
Only index persons 10647 10647 -
Unadjusted period prevalence (%)
Whole population 0.31 0.31 -
Only index persons 0.39 0.39 -
Median age at first event (years)
Whole population - 29.51 -
Only index persons - 29.48 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1479 1479 -
Unadjusted period prevalence (%) 0.53 0.53 -
Median age at first event (years) 29.69 29.69 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1542
Matched controls
15420
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
13100.8
307.7
728
*
63494
ICD-8 Finland
Other complications of pregnancy, Insufficientia cervicis
+∞
307.7
719
*
O60
ICD-10 Finland
Preterm labour and delivery
15.8
275.9
252
188
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
6.7
254.9
524
1098
6545A
ICD-9 Finland
Abnormality of organs and soft tissues of pelvis, Cervical incompetence[INSUFFICIENTIA CERVICIS UTERI, RASKAUDEN AIKANA]
+∞
165.7
156
*
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
386.9
143.4
142
*
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
8.3
141.0
198
268
8702
FHL
Placement of Cerglagen during pregnancy
737.1
139.1
135
*
63497
ICD-8 Finland
Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis
9.0
137.3
180
224
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
10.9
126.5
141
141
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
6.1
115.2
217
400
MAB00
NOMESCO Finland
Cerclage of cervix of pregnant uterus
1182.4
114.1
110
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.9
93.4
332
1019
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
3.7
85.7
333
1081
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
10.9
66.9
73
70
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.7
66.1
493
2291
O20.0
ICD-10 Finland
Threatened abortion
6.1
60.3
108
187
O30.0
ICD-10 Finland
Twin pregnancy
8.5
60.2
79
97
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
3.4
57.9
230
746
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
+∞
57.7
55
*
Y6099
ICD-8 Finland
Prenatal care and observation
3.7
52.5
185
554
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
3.3
52.0
217
724
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
12.4
48.1
48
40
W84
ICPC
Pregnancy high risk
3.6
43.6
153
455
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
7.2
43.0
65
94
64300
ICD-8 Finland
Spontaneous abortion, With sepsis
10.3
38.2
43
43
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
6.3
38.1
65
107
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
3.9
37.0
112
300
XMA22
NOMESCO Finland
General examination of pregnant woman
3.1
35.6
165
581
Z39.2
ICD-10 Finland
Routine postpartum follow-up
2.2
35.3
399
2143
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
3.8
34.5
110
306
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.3
33.5
295
1427
SPAT1379
SPAT
Health check-up of pregnant person
2.2
31.8
341
1785
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
5.1
30.7
66
135
MAB03
NOMESCO Finland
Removal of cerclage of cervix uteri before childbirth
+∞
30.3
29
*
63499
ICD-8 Finland
Other complications of pregnancy, Other
4.6
30.1
73
165
N88.3
ICD-10 Finland
Incompetence of cervix uteri
158.1
29.8
31
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
2.0
28.9
373
2085
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
7.0
28.1
43
63
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.2
27.0
282
1453
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.5
26.8
183
786
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.8
25.4
690
4851
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
3.1
25.2
110
373
O34.0
ICD-10 Finland
Maternal care for congenital malformation of uterus
+∞
25.1
24
*
SPAT1197
SPAT
Extensive health check-up of expecting family
2.0
24.9
352
2019
W78
ICPC
Pregnancy
1.9
24.8
428
2623
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
24.6
316
1753
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
4.0
24.0
69
178
O32.1
ICD-10 Finland
Maternal care for breech presentation
3.2
24.0
100
330
N97.0
ICD-10 Finland
Female infertility associated with anovulation
3.7
23.7
76
212
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.8
23.6
515
3380
Z37.2
ICD-10 Finland
Twins, both liveborn
9.8
23.3
27
28
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.2
22.6
211
1035
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.7
22.6
599
4145
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
3.7
22.5
74
210
O47.9
ICD-10 Finland
False labour, unspecified
3.9
22.2
67
179
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
5.9
21.9
39
67
8502
FHL
Evacuation and abrasion
2.9
21.4
103
369
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
3.7
21.1
69
195
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
2.8
20.8
106
392
O82.0
ICD-10 Finland
Delivery by elective caesarean section
3.5
19.9
70
208
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
3.1
18.7
79
263
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.6
18.5
113
459
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
15.5
18.0
29
19
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.0
17.9
226
1237
ZXD00
NOMESCO Finland
Emergency procedure
3.6
17.5
57
161
64598
ICD-8 Finland
Other abortion
4.8
17.3
39
83
66100
ICD-8 Finland
Occipital presentation
4.6
16.9
40
89
6400A
ICD-9 Finland
Haemorrhage in early pregnancy, Threatened abortion
5.2
16.8
34
66
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
5.2
16.8
34
66
SPAT1380
SPAT
Postpartum check-up
1.9
16.7
260
1521
ZXD05
NOMESCO Finland
Urgent procedure
1.7
16.7
447
3051
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
7.0
16.6
25
36
63495
ICD-8 Finland
Other complications of pregnancy, Effluxus liquoris amnii praetemporarius
6.0
16.5
29
49
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
6.2
16.4
28
46
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
3.4
16.4
59
178
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
6.2
16.0
27
44
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
3.6
15.6
52
149
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
4.3
15.6
40
95
N96
ICD-10 Finland
Habitual aborter
5.8
15.4
28
49
W29
ICPC
Pregnancy symptom/complaint other
2.6
15.2
87
342
W92
ICPC
Compl labour/ delivery livebirth
3.0
14.8
67
232
O84.8
ICD-10 Finland
Other multiple delivery
21.3
14.7
21
10
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.0
14.3
173
929
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.5
14.3
35
80
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
2.9
14.3
69
248
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
2.7
14.2
77
294
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.8
14.2
238
1422
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.7
14.1
275
1716
B01AB05
ATC
enoxaparin; parenteral
1.6
13.6
463
3320
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
3.3
13.5
51
159
MAA00
NOMESCO Finland
Amniocentesis
3.3
13.5
51
159
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
141.2
13.5
14
*
64394, ,
ICD-8 Finland
141.2
13.5
14
*
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
3.4
13.2
47
141
O30.01
ICD-10 Finland
Twin pregnancy with a shared chorionic sac and a separate amniotic sac
22.7
12.9
18
8
C08CA05
ATC
nifedipine; systemic
2.5
12.8
80
329
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
12.6
490
3604
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
12.4
635
4938
G02CB01
ATC
bromocriptine; systemic
3.4
12.4
44
132
ZXE00
NOMESCO Finland
One hour or less
1.5
12.2
582
4458
63496
ICD-8 Finland
Other complications of pregnancy, Labores inhibiti
3.4
12.2
43
128
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
5.3
12.0
24
46
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
4.6
11.9
28
62
63299
ICD-8 Finland
Haemorrhage of pregnancy, Other and unspecified
5.3
11.6
23
44
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
5.4
11.4
22
41
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
3.0
11.3
49
166
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
3.1
11.2
46
151
MA3AE
NOMESCO Finland
Combined first trimester screening
1.9
11.1
156
880
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
3.1
10.9
44
143
ULA02
NOMESCO Finland
Kolposcopy
1.7
10.9
223
1404
O02.1
ICD-10 Finland
Missed abortion
2.0
10.9
119
617
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.5
10.8
474
3552
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
2.9
10.8
50
176
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
3.0
10.8
47
160
MAG00
NOMESCO Finland
Assisted breech delivery
5.0
10.7
23
47
O36.4
ICD-10 Finland
Maternal care for intrauterine death
9.2
10.5
21
23
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
4.9
10.3
22
45
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.6
10.1
299
2057
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
10.0
647
5196
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.1
10.0
92
447
OAA11, ,
SPAT
1.8
10.0
157
916
O03.5
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by genital tract and pelvic infection
16.8
9.9
15
9
63490
ICD-8 Finland
Other complications of pregnancy, Abortus habitualis
20.2
9.8
14
7
WX320
NOMESCO Finland
Spinalanesthesy
1.5
9.8
349
2502
MBA05
NOMESCO Finland
Curettage of uterus after abortion
3.4
9.7
35
106
G03GA01
ATC
chorionic gonadotrophin; parenteral
2.2
9.7
83
392
SPAT1357
SPAT
Monitoring of problem during pregnancy
2.5
9.7
62
258
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
4.5
9.6
23
52
W27
ICPC
Fear of complications of pregnancy
3.5
9.5
32
93
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
3.1
9.4
38
124
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.7
9.4
51
196
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.8
9.0
133
762
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
2.8
9.0
43
155
W03
ICPC
Antepartum bleeding
3.7
8.9
27
73
B02AA02
ATC
tranexamic acid; systemic
1.5
8.8
286
2006
J01DB01
ATC
cefalexin; oral
1.5
8.7
1260
11534
65696
ICD-8 Finland
Delivery complicated by malpresentation of foetus, Complete or incomplete breech presentation
4.0
8.6
24
61
O42.2
ICD-10 Finland
Premature rupture of membranes, labour delayed by therapy
27.7
8.5
11
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
1.7
8.5
144
860
W85
ICPC
Gestational diabetes
1.9
8.5
105
569
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.7
8.4
180
1143
O72.0
ICD-10 Finland
Third-stage haemorrhage
2.4
8.4
56
238
64595
ICD-8 Finland
Other abortion, Haemorrhagia post abortum NUD
4.9
8.4
18
37
Z31.5
ICD-10 Finland
Genetic counselling
1.9
8.4
111
615
6225A
ICD-9 Finland
Noninflammatory disorders of cervix, Incompetence of cervix
+∞
8.3
8
*
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.3
8.3
59
258
Q51.2
ICD-10 Finland
Other doubling of uterus
10.8
8.3
15
14
O80.1
ICD-10 Finland
Spontaneous breech delivery
3.9
8.2
23
59
N97.9
ICD-10 Finland
Female infertility, unspecified
1.8
8.0
118
675
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
2.5
8.0
47
188
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
3.6
8.0
26
74
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.6
7.9
214
1438
65007
ICD-8 Finland
Delivery without mention of complication, Multiple pregnancy, all presentations
4.7
7.9
18
39
SPAT1263
SPAT
Sampling
1.4
7.9
638
5261
Z39.1
ICD-10 Finland
Care and examination of lactating mother
2.4
7.9
54
233
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
1.9
7.7
92
492
WX402
NOMESCO Finland
General anaesthesia
1.4
7.6
338
2515
ULC02
NOMESCO Finland
Hysteroscopy
1.9
7.6
96
525
O21
ICD-10 Finland
Excessive vomiting in pregnancy
3.4
7.4
26
78
A02BC01
ATC
omeprazole; systemic
1.4
7.3
385
2952
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
2.9
7.3
32
110
MBA04
NOMESCO Finland
Curettage of uterus after delivery
3.7
7.2
22
60
Y4300
ICD-8 Finland
Preventive sterilization, Legal sterilization, medical reasons (illness or physical injury)
2.4
7.1
47
200
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.6
7.0
147
931
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
2.3
7.0
48
208
SPAT1196
SPAT
Monitoring of normal pregnancy
1.7
6.8
137
856
SPAT1260
SPAT
Consultation of another employee
1.5
6.8
252
1808
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
3.8
6.8
20
53
G02CA02
ATC
buphenine; parenteral
11.0
6.8
12
11
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1.9
6.7
78
414
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.1
6.7
65
324
Z37.1
ICD-10 Finland
Single stillbirth
22.6
6.7
9
*
LDD00
NOMESCO Finland
Suture of cervix uteri
22.6
6.7
9
*
O80.8
ICD-10 Finland
Other single spontaneous delivery
1.8
6.6
104
609
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
1.5
6.5
197
1359
G03DB01
ATC
dydrogesterone; oral
1.5
6.4
254
1846
65200
ICD-8 Finland
Occipital presentation
3.8
6.4
19
51
63899
ICD-8 Finland
Hyperemesis gravidarum, Without mention of neuritis
4.1
6.4
17
42
W90
ICPC
Uncompl labour/delivery livebirth
1.7
6.3
125
778
W05
ICPC
Pregnancy vomiting/nausea
2.8
6.3
31
114
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
2.9
6.3
29
103
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
2.9
6.3
29
103
TLW00
NOMESCO Finland
Insemination
2.3
6.3
45
199
8703
FHL
Removal of Cerglagen under anesthesia
+∞
6.3
6
*
6546B
ICD-9 Finland
Abnormality of organs and soft tissues of pelvis, Other congenital or acquired abnormality of cervix[MALEFORMATIONES ALIAE CERVICIS UTERI,SYNN AIKANA]
+∞
6.3
6
*
O34.8
ICD-10 Finland
Maternal care for other abnormalities of pelvic organs
+∞
6.3
6
*
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.2
921
8181
O03.3
ICD-10 Finland
Spontaneous abortion, Incomplete, with other and unspecified complications
6.3
6.2
15
24
Z82.7
ICD-10 Finland
Family history of congenital malformations, deformations and chromosomal abnormalities
6.3
6.2
15
24
SFA20
NOMESCO Finland
Two-surface restoration
1.3
6.1
902
8003

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
255
1252
2.24
27.56
4.7
3.8
—
—
—
0
0
150
638
2.50
22.30
1.6
1.5
61.74
62.89
ug/l
0.11
150
638
614
4368
1.67
20.33
4.1
3.3
0.00
0.24
estimate
0.67
249
1358
303
1767
1.89
19.97
1.8
1.6
1105.90
1012.80
mu/l
0.90
271
1504
588
4385
1.55
14.71
4.7
4.1
0.00
0.00
estimate
1.34
287
1615
957
7962
1.53
14.18
4.4
4.0
0.00
0.00
estimate
0.50
290
1668
970
8121
1.52
13.73
4.5
4.0
0.00
0.01
estimate
1.74
283
1643
962
8048
1.52
13.60
4.5
4.0
0.01
4.07
estimate
1.33
291
1699
750
5984
1.49
13.18
4.3
3.8
0.00
0.10
estimate
0.75
248
1355
197
1149
1.82
12.62
1.6
1.4
—
—
—
0
0
206
1233
1.77
12.09
3.2
2.2
6148.44
6681.39
u/l
0.11
124
531
401
2874
1.53
11.45
2.1
1.8
—
—
—
0
0
184
1083
1.79
11.41
3.7
3.3
1.23
1.24
mmol/l
0.14
157
914
1127
9982
1.48
10.24
5.9
4.8
3100.21
2130.85
e6/l
0.16
29
114
298
2058
1.56
9.91
2.2
1.9
—
—
—
0
0
468
3561
1.45
9.68
2.1
1.8
—
—
—
0
0
35
108
3.29
9.47
1.4
1.2
—
—
—
0
0
29
81
3.63
9.13
3.6
3.3
—
—
—
0
0
918
7935
1.39
8.77
4.6
4.4
6.46
6.41
mmol/l
0.37
852
7321
659
5448
1.37
8.05
3.3
2.8
—
—
—
0
0
370
2799
1.42
7.61
1.9
1.7
20339441.92
24407516.12
pmol/l
0.07
295
2319
566
4604
1.36
7.52
3.8
3.3
30.18
51.40
ng/l
0.56
324
2812
538
4375
1.35
7.06
3.1
2.5
56.05
59.52
u/l
1.06
485
4012
51
226
2.30
7.02
3.8
3.0
2.07
2.64
mmol/l
0.90
34
161
1286
11947
1.46
6.99
19.4
17.3
13.47
13.47
%
0.01
1268
11781
822
7150
1.32
6.65
3.8
2.7
—
—
estimate
—
0
0
61
300
2.08
6.52
1.4
1.3
—
—
—
0
0
56
272
2.10
6.20
1.4
1.3
170.53
163.28
au/ml
0.17
17
79
382
2996
1.37
6.19
2.6
2.6
8.16
8.48
e6/l
0.13
345
2713
188
1303
1.50
6.02
2.5
2.5
6.16
6.16
ph
0.04
140
864
748
6487
1.30
5.90
12.9
10.5
0.00
0.00
e9/l
0.22
635
5293
17
45
3.81
5.82
1.5
1.2
—
—
—
0
0
587
4945
1.30
5.72
2.3
1.7
—
—
—
0
0
602
5099
1.30
5.60
3.1
2.9
—
—
—
0
0
71
394
1.84
5.41
2.5
2.0
4.92
4.50
umol/l
0.22
54
276
814
7187
1.28
5.39
6.4
6.0
9.66
10.10
umol/l
1.02
757
6805
1435
13783
1.59
5.15
16.6
15.5
3.91
3.92
mmol/l
0.41
1408
13439
1433
13764
1.58
5.08
16.3
15.3
139.58
139.63
mmol/l
0.31
1411
13452
50
252
2.02
5.07
3.9
3.4
3.84
4.13
e9/l
0.38
50
252
1440
13851
1.60
5.02
15.7
13.9
18.67
20.42
mg/l
1.41
1242
11241
730
6433
1.26
4.64
3.5
3.5
6.28
6.28
ph
0.03
443
3558
708
6229
1.25
4.53
2.1
2.1
—
—
—
0
0
632
5504
1.25
4.38
9.3
10.8
1.10
1.14
inr
1.88
545
4520
173
1258
1.42
4.34
4.7
4.7
0.03
0.40
%
0.62
32
258
417
3460
1.28
4.33
4.9
4.5
—
—
—
0
0
1282
12142
1.33
4.23
5.7
5.1
14.55
14.62
pmol/l
0.49
1185
11284
314
2524
1.31
4.15
2.6
2.8
486.31
497.40
mosm/kgh2o
0.41
273
2204
168
1226
1.42
4.13
4.4
4.2
0.77
0.70
%
0.15
35
305
17
57
3.00
4.13
1.5
1.4
—
—
—
0
0
513
4399
1.25
3.99
3.3
3.2
135.72
49.34
e6/l
0.39
406
3250
77
480
1.64
3.97
1.3
1.3
9.85
11.73
u/l
1.00
71
387
406
3394
1.27
3.92
1.8
1.8
1.23
1.02
mg/l
0.80
318
2594
167
1235
1.40
3.82
4.7
4.5
0.17
0.08
%
0.67
29
275
217
1675
1.34
3.80
1.3
1.3
—
—
—
0
0
31
147
2.13
3.76
2.4
1.9
32.39
31.73
pg
0.43
31
147
55
318
1.76
3.75
4.2
3.2
55.65
58.20
%
0.68
55
318
1408
13581
1.42
3.73
6.7
6.2
1.72
1.84
mu/l
3.93
1326
12753
172
1284
1.38
3.72
4.6
4.4
1.28
0.97
%
0.49
34
325
86
563
1.56
3.65
2.3
2.1
20.01
20.48
s
0.57
69
500
553
4823
1.23
3.60
3.3
3.0
28.02
29.66
u/l
0.46
515
4554
549
4794
1.23
3.51
5.8
6.1
—
—
—
0
0
25
113
2.23
3.42
1.2
1.2
—
—
—
0
0
144
1061
1.39
3.38
1.2
1.3
20.95
22.45
iu/l
0.23
129
906
604
5343
1.21
3.36
4.0
3.9
87.59
84.41
e6/l
0.06
432
3464
278
2260
1.28
3.34
2.3
2.4
13.10
13.41
umol/l
0.31
255
2098
486
4218
1.22
3.25
4.1
3.7
7.40
7.40
ph
0.96
374
2970
267
2169
1.28
3.22
3.3
3.0
0.82
0.82
mmol/l
0.21
248
2049
15
55
2.74
3.16
1.3
1.2
79.67
73.15
ug/l
0.18
15
55
472
4100
1.22
3.11
2.4
2.1
—
—
—
0
0
202
1593
1.31
3.06
1.6
1.6
—
—
—
0
0
256
2083
1.27
3.05
2.2
2.4
2.48
2.41
g/l
1.12
228
1921
28
140
2.02
3.01
1.5
1.9
91.04
90.27
%
0.37
28
140
234
1893
1.28
2.92
2.3
2.5
20.47
22.21
%
1.32
211
1758
42
245
1.73
2.85
4.1
3.2
—
—
—
0
0
422
3655
1.21
2.83
3.0
3.0
—
0.00
estimate
—
0
6
73
490
1.51
2.83
1.2
1.4
4.26
3.44
ug/l
0.84
68
459
137
1033
1.36
2.83
1.8
1.5
65.75
61.21
ug/l
0.39
114
887
1115
10538
1.21
2.83
8.4
7.8
74.92
75.57
u/l
0.26
1049
9975
30
158
1.92
2.81
2.4
1.9
0.92
0.89
%
0.14
18
96
93
658
1.44
2.78
1.4
1.3
—
—
—
0
0
872
8068
1.19
2.78
3.7
3.3
73.53
77.01
ug/l
0.38
819
7590
40
232
1.74
2.77
1.3
1.2
—
—
—
0
0
228
1852
1.27
2.75
2.8
2.0
29.28
29.06
s
0.20
219
1790
115
847
1.39
2.75
1.5
1.7
273.22
299.15
mu/l
0.81
101
753
28
146
1.93
2.71
3.2
2.6
—
—
—
0
0
231
1896
1.26
2.56
1.8
1.9
—
—
—
0
0
1129
11813
0.83
2.50
19.1
18.1
332.07
331.13
g/l
3.28
1123
11745
502
4461
1.19
2.50
3.4
3.3
—
0.75
—
0
12
459
4056
1.19
2.43
4.7
4.2
10.62
7.74
mg/mmol
0.61
248
2316
23
426
0.53
2.40
7.1
8.7
—
—
—
0
0
148
1164
1.30
2.32
2.9
3.4
4.46
4.51
pmol/l
0.31
136
1038
254
2134
1.23
2.29
1.2
1.2
—
—
—
0
0
565
5115
1.17
2.19
3.2
3.4
2.35
2.36
mmol/l
2.28
521
4658
741
6854
1.16
2.14
6.1
6.3
1.22
1.22
mmol/l
0.80
599
5924
655
6007
1.16
2.12
2.0
1.9
1.32
1.31
mmol/l
0.17
525
5125
429
3811
1.17
2.10
3.2
3.0
0.28
0.36
e6/l
1.05
331
2685
270
2304
1.21
2.08
2.4
2.3
108.56
106.77
ug/g
0.04
202
1795
1523
15065
1.89
2.08
24.7
21.8
263.81
264.97
e9/l
0.31
1507
14792
107
818
1.33
2.08
1.8
1.5
—
—
—
0
0
1355
13164
1.24
2.07
5.0
4.8
5.74
5.72
mmol/l
0.19
1222
12166
36
222
1.64
2.07
1.2
1.3
1.25
1.59
nmol/l
1.09
31
193
538
4870
1.16
2.07
3.2
2.1
—
—
—
0
0
1523
15068
1.87
2.03
24.6
21.7
30.15
30.10
pg
0.58
1515
14936
1523
15068
1.87
2.03
24.9
22.0
42.19
39.62
%
0.49
1514
14933
1523
15068
1.87
2.03
24.6
21.7
90.73
90.70
fl
0.08
1515
14936
1523
15069
1.87
2.01
24.7
21.7
4.40
4.41
e12/l
0.42
1500
14749
734
6808
1.15
2.00
6.0
6.3
8.29
8.41
%
0.59
684
6374
1523
15070
1.86
1.99
24.7
21.8
6.99
6.70
e9/l
3.98
1501
14748
731
6785
1.15
1.95
6.0
6.3
0.69
0.70
%
0.19
681
6333
1523
15075
1.83
1.91
24.9
21.9
131.87
132.00
g/l
0.17
1515
14944
364
3214
1.17
1.91
2.3
2.4
304.46
307.98
umol/l
0.31
312
2827
41
267
1.55
1.91
3.6
3.7
31.92
19.75
mg/l
1.00
29
176
182
1507
1.24
1.90
2.2
2.1
0.00
0.03
estimate
1.06
40
314
192
1601
1.23
1.88
4.3
4.8
1.04
1.05
mmol/l
0.28
187
1465
137
1101
1.27
1.86
2.9
3.0
10.41
10.25
g/l
0.13
127
1017
111
869
1.30
1.85
1.3
1.2
—
—
—
0
0
240
2050
1.20
1.84
1.9
1.7
1272.05
1167.74
nmol/l
0.86
179
1518
730
6796
1.14
1.83
6.0
6.3
2.80
2.69
%
0.74
680
6352
70
513
1.38
1.81
1.8
1.9
1.33
1.51
g/l
0.88
58
456
29
176
1.66
1.80
1.0
1.1
—
—
—
0
0
497
4513
1.15
1.79
3.6
3.4
7.02
6.78
mmol/l
0.57
416
3861
6
18
3.34
1.74
1.0
1.1
—
—
—
0
0
39
257
1.53
1.74
1.4
1.3
3.14
4.38
u/ml
0.52
14
114
1473
14496
1.36
1.74
18.8
17.4
67.24
68.03
umol/l
0.85
1461
14325
87
1125
0.76
1.73
2.9
3.0
7.38
7.38
ph
0.25
54
607
749
7011
1.13
1.68
6.0
6.2
28.81
29.17
%
0.42
706
6646
23
136
1.70
1.59
1.1
1.2
—
—
—
0
0
392
3528
1.15
1.59
3.7
4.2
1.02
1.45
kg/l
0.50
313
2352
32
207
1.56
1.57
1.2
1.3
0.14
0.27
nmol/l
0.80
25
156
20
114
1.76
1.56
1.0
1.1
0.35
2.84
u/ml
—
8
35
63
836
0.74
1.53
5.2
2.5
—
—
—
0
0
100
797
1.27
1.49
1.8
1.5
—
—
—
0
0
353
3167
1.15
1.49
4.5
3.9
—
—
—
0
0
86
1087
0.78
1.47
2.9
3.1
1.81
1.80
mmol/l
0.01
79
962
46
327
1.42
1.46
1.7
1.3
—
—
—
0
0
93
738
1.28
1.44
2.1
2.1
0.00
0.01
estimate
0.80
32
254
42
589
0.71
1.44
2.0
2.4
1.12
1.22
%
0.39
42
583
440
4015
1.13
1.44
3.9
3.5
53.89
38.42
mg/l
0.67
252
2325
5
16
3.13
1.44
1.4
1.1
—
—
—
0
0
6
22
2.73
1.43
1.5
1.0
—
—
—
0
0
61
458
1.35
1.41
1.4
1.4
259.84
306.42
ug/g
0.97
31
257
186
1594
1.19
1.41
2.1
2.3
7.31
6.10
umol/l
0.32
152
1372
646
6041
1.12
1.40
5.2
4.5
36.09
36.27
g/l
0.36
599
5678
7
29
2.42
1.39
1.0
1.1
—
—
—
0
0
108
1319
0.81
1.39
3.8
3.7
7.37
7.35
ph
0.44
75
930
452
4141
1.13
1.38
1.4
1.3
0.78
1.61
u/ml
2.65
121
1091
652
6111
1.12
1.34
5.4
5.6
1.22
1.22
mmol/l
0.60
599
5630
97
782
1.26
1.34
1.7
1.5
1.23
1.27
mm
0.47
75
576
147
1241
1.20
1.32
1.5
1.4
—
—
—
0
0
27
176
1.54
1.32
1.7
1.6
24.56
21.50
ng/l
0.42
27
176
35
244
1.44
1.26
5.0
3.6
461.52
1444.34
u/ml
0.44
30
228
37
261
1.43
1.25
1.1
1.1
30.37
2431.65
iu/ml
—
9
54
34
236
1.45
1.25
1.2
1.3
0.57
0.66
nmol/l
0.99
34
227
26
171
1.53
1.23
2.2
2.3
—
—
—
0
0
137
1158
1.20
1.23
1.3
1.3
223.05
170.92
u/ml
0.22
123
1070
12
63
1.91
1.23
2.3
1.7
109.00
525.31
nmol/24h
0.46
12
63
487
4513
1.12
1.21
3.1
3.0
0.00
0.01
—
9
76
70
550
1.29
1.21
1.2
1.2
—
—
—
0
0
26
172
1.52
1.21
4.7
4.3
76.10
103.13
u/ml
0.18
12
50
122
1022
1.21
1.21
2.7
2.4
0.37
0.49
e6/l
0.36
116
971
27
181
1.50
1.18
1.3
1.2
17.89
20.62
u/l
0.17
21
150
728
6898
1.10
1.18
5.7
6.1
56.67
56.62
%
0.04
700
6583
95
778
1.24
1.17
1.9
2.0
—
—
—
0
0
10
50
2.01
1.16
1.6
1.8
8.30
7.28
%
—
10
50
32
450
0.70
1.16
1.2
1.2
—
—
—
0
0
5
20
2.50
1.15
1.2
1.2
—
—
—
0
0
5
20
2.50
1.15
5.0
3.9
—
—
—
0
0
13
72
1.81
1.15
1.2
1.7
1.00
2.57
u/field
—
7
53
22
142
1.56
1.14
1.2
1.3
0.03
1.33
u/ml
—
7
73
0
36
0.00
1.14
0.0
1.1
—
17.70
—
0
27
30
208
1.45
1.13
1.7
1.4
34.00
35.87
nmol/l
0.10
25
192
104
864
1.22
1.13
2.2
1.9
1.52
1.41
g/l
0.12
95
790
17
103
1.66
1.13
1.0
1.0
0.11
0.23
u/ml
—
6
16
19
120
1.59
1.08
2.5
3.1
18.39
25.51
mu/l
0.79
19
115
55
702
0.78
1.07
2.2
2.5
134.89
128.63
g/l
1.73
55
682
174
1523
1.16
1.06
2.4
2.1
390.54
379.52
nmol/l
0.25
164
1401
354
3247
1.12
1.06
1.4
1.3
24.43
29.48
iu/ml
0.34
94
977
233
2084
1.14
1.05
1.6
1.5
—
—
—
0
0
871
8357
1.10
1.04
8.6
9.4
4.24
3.97
e9/l
2.85
766
7291
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
57
447
1.29
1.03
1.1
1.1
0.78
5.78
eliau/ml
—
8
66
16
98
1.64
1.03
1.5
1.9
10.31
13.90
%
1.27
16
93
10
53
1.89
1.01
1.8
1.8
32.60
30.19
%
—
10
53
421
3909
1.11
1.00
2.4
2.3
2.64
2.68
mg/l
0.12
368
3373
154
1343
1.16
0.99
2.6
2.6
1.69
1.83
%
1.46
137
1203
330
3026
1.12
0.99
1.3
1.3
6.23
12.10
u/ml
1.28
124
1179
11
61
1.81
0.98
1.4
1.5
121.00
148.80
mmol/24h
0.81
11
61
55
433
1.28
0.98
2.1
1.8
—
—
—
0
0
38
284
1.35
0.97
1.3
2.4
0.93
0.90
nmol/l
0.10
32
231
28
199
1.41
0.96
2.9
2.3
13.29
13.13
%
0.53
28
199
218
1955
1.13
0.96
1.3
1.3
—
—
—
0
0
774
7408
1.09
0.95
5.7
6.2
0.04
0.04
e9/l
0.09
663
6400
772
7389
1.09
0.94
5.7
6.2
0.55
0.54
e9/l
0.86
663
6389
27
374
0.72
0.94
2.1
2.8
0.47
1.85
index
2.24
17
174
1464
14481
1.22
0.93
12.4
11.5
23.89
23.13
u/l
0.95
1416
14054
45
348
1.30
0.92
1.4
1.3
4.37
38.89
e6/l
1.14
35
249
1375
13536
1.15
0.92
5.0
4.8
4.75
4.78
mmol/l
0.44
1276
12714
430
4015
1.10
0.91
1.7
1.6
20.55
21.31
nmol/l
0.51
358
3383
16
102
1.57
0.90
1.6
1.8
75.81
76.17
%
0.04
16
96
45
350
1.29
0.89
1.6
1.3
711.41
351.23
e6/l
0.23
37
268
135
1178
1.16
0.88
1.3
1.3
—
—
—
0
0
27
194
1.40
0.88
1.1
1.3
—
—
nmol/l
—
0
0
53
422
1.27
0.88
1.1
1.1
4.56
2.38
u/ml
0.56
27
218
1368
13471
1.14
0.87
4.9
4.7
1.56
1.57
mmol/l
0.61
1261
12587
11
180
0.61
0.86
1.2
1.0
—
—
—
0
0
211
1903
1.13
0.86
2.7
3.1
4.05
4.47
e9/l
1.02
187
1677
26
187
1.40
0.85
2.4
2.3
—
—
—
0
0
37
283
1.31
0.84
1.3
1.2
255.32
251.03
u/ml
0.03
25
182
36
275
1.32
0.82
1.8
1.6
269.13
366.49
mu/l
3.29
30
225
0
26
0.00
0.78
0.0
1.4
—
—
—
0
0
66
550
1.21
0.76
2.1
2.1
2.25
14.20
iu/l
0.61
26
225
9
54
1.67
0.74
1.4
2.0
0.00
0.00
estimate
—
9
54
79
672
1.19
0.73
1.1
1.1
—
—
—
0
0
37
290
1.28
0.73
1.9
2.3
—
—
—
0
0
5
25
2.00
0.72
1.0
1.0
—
—
—
0
0
5
25
2.00
0.72
1.0
1.0
—
—
—
0
0
5
25
2.00
0.72
1.0
1.0
—
—
—
0
0
255
2350
1.10
0.72
1.3
1.4
618.54
581.13
titre
0.08
41
530
364
3418
1.09
0.68
3.3
2.9
699.91
788.54
ng/l
0.48
301
2868
5
28
1.79
0.66
2.4
2.0
—
—
—
0
0
228
2102
1.10
0.65
1.6
1.5
—
—
—
0
0
84
730
1.16
0.63
3.2
2.9
1.02
1.02
ratio
0.07
73
647
14
97
1.45
0.59
1.1
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
2.3
—
3.62
—
0
12
28
220
1.28
0.57
2.6
2.4
70.04
74.07
ug/min
0.02
11
132
5
86
0.58
0.56
1.0
1.3
—
—
—
0
0
40
483
0.82
0.56
4.7
3.3
—
—
—
0
0
43
357
1.21
0.55
1.0
1.1
3.90
4.15
u/ml
0.04
21
183
30
239
1.26
0.55
1.1
1.2
—
—
—
0
0
1384
13696
1.10
0.55
5.6
5.4
2.77
2.77
mmol/l
0.06
1274
12818
9
60
1.50
0.54
1.7
1.2
15.13
14.08
pmol/l
—
9
45
9
61
1.48
0.53
1.0
1.0
—
—
—
0
0
10
66
1.52
0.52
1.4
1.9
—
—
—
0
0
423
4038
1.07
0.52
2.2
2.1
171.56
165.44
u/l
0.06
392
3835
9
133
0.67
0.52
1.0
1.1
—
10.38
—
0
41
49
571
0.85
0.48
1.3
1.3
—
—
—
0
0
7
109
0.64
0.48
12.3
14.8
0.53
0.64
mmol/l
—
7
103
47
548
0.85
0.47
1.1
1.6
—
9.71
—
0
14
168
1811
0.92
0.47
1.5
1.4
—
—
—
0
0
7
48
1.46
0.46
1.0
1.1
—
—
—
0
0
21
164
1.28
0.46
1.9
2.0
8.75
30.50
u/ml
0.47
21
164
34
282
1.21
0.46
1.1
1.1
—
—
—
0
0
33
273
1.21
0.46
3.2
2.8
8.31
8.25
kpa
0.09
33
267
8
120
0.66
0.45
1.5
1.2
—
—
—
0
0
49
567
0.86
0.45
1.1
1.1
0.82
0.84
g/l
0.37
49
567
34
283
1.21
0.45
1.1
1.1
—
—
—
0
0
9
131
0.69
0.43
1.1
1.2
—
—
—
0
0
48
553
0.86
0.43
1.1
1.1
1.58
1.60
g/l
0.18
48
553
79
708
1.12
0.42
2.5
2.3
—
—
—
0
0
50
434
1.16
0.42
1.2
1.2
35.22
44.22
u/ml
—
6
46
778
7594
1.05
0.42
5.8
6.2
2.01
1.97
e9/l
0.27
690
6726
784
7655
1.05
0.42
5.9
6.4
0.19
0.18
e9/l
1.19
687
6710
20
158
1.27
0.42
1.4
1.8
47.85
55.94
%
0.39
13
96
36
305
1.18
0.41
1.4
1.4
21.92
21.96
u/l
0.00
26
257
0
17
0.00
0.40
0.0
1.0
—
84.71
—
0
17
146
1571
0.92
0.40
5.7
6.3
105.12
104.24
mmol/l
1.80
146
1571
33
278
1.19
0.40
1.0
1.1
4.50
5.02
u/ml
0.05
11
118
26
314
0.83
0.40
1.1
1.1
2.71
18.75
au/ml
—
7
82
0
18
0.00
0.40
0.0
1.3
—
1.37
—
0
8
361
3461
1.06
0.39
3.8
3.7
98.00
95.49
%
1.37
349
3366
19
237
0.80
0.39
1.3
1.6
—
—
—
0
0
29
242
1.20
0.39
1.0
1.1
—
—
—
0
0
225
2128
1.07
0.38
2.9
2.9
4.30
4.29
e6/l
0.00
117
946
52
457
1.14
0.38
3.2
2.9
240.65
315.75
mg/l
0.40
26
163
9
66
1.37
0.38
1.7
2.4
49.41
54.20
umol/l
—
9
53
9
67
1.35
0.38
1.0
1.0
—
9.67
—
0
11
89
976
0.91
0.38
7.5
7.7
—
—
—
0
0
31
262
1.19
0.37
1.4
1.2
—
—
—
0
0
16
125
1.28
0.37
1.1
1.0
—
—
—
0
0
361
3469
1.05
0.37
1.6
1.5
2.12
2.19
g/l
0.33
220
2115
22
267
0.82
0.36
3.3
2.5
1.42
1.49
mmol/l
0.13
22
259
40
347
1.16
0.36
1.0
1.1
1.38
1.20
u/ml
0.05
11
138
40
348
1.15
0.35
1.3
2.1
—
—
—
0
0
14
178
0.78
0.34
1.6
1.3
—
—
—
0
0
14
178
0.78
0.34
1.6
1.3
—
—
—
0
0
14
178
0.78
0.34
1.6
1.3
—
—
—
0
0
14
178
0.78
0.34
1.6
1.3
—
—
—
0
0
29
246
1.18
0.34
1.0
1.0
1.93
2.36
eliau/ml
0.24
14
118
19
154
1.24
0.34
2.3
2.8
—
—
—
0
0
1280
12679
1.06
0.33
4.1
4.0
1.21
1.21
mmol/l
0.06
1175
11728
19
232
0.82
0.33
1.4
1.6
0.69
0.66
g/l
0.05
13
188
131
1224
1.08
0.33
3.2
3.5
33.86
61.84
u/ml
1.49
123
1179
71
645
1.11
0.33
1.2
1.2
—
—
—
0
0
972
9571
1.04
0.33
3.4
3.0
35.20
36.98
u/l
0.51
920
9019
121
1297
0.93
0.32
7.2
7.1
13.22
12.92
kpa
0.26
116
1247
121
1297
0.93
0.32
7.2
7.1
5.02
5.11
kpa
0.54
115
1251
7
52
1.35
0.31
1.0
1.5
—
—
—
0
0
63
694
0.90
0.31
8.7
8.5
24.59
24.37
mmol/l
0.19
63
681
11
142
0.77
0.30
1.2
1.1
—
—
—
0
0
7
56
1.25
0.29
2.4
1.6
—
—
—
0
0
8
108
0.74
0.29
1.0
1.1
—
—
—
0
0
12
151
0.79
0.28
1.2
1.1
—
—
—
0
0
47
521
0.90
0.27
1.0
1.1
0.76
0.61
ratio
—
5
57
33
374
0.88
0.27
3.2
3.9
23.64
31.86
u/ml
0.51
33
369
45
405
1.11
0.26
2.4
1.5
0.57
0.42
nmol/l
0.31
36
340
100
936
1.07
0.26
1.6
1.7
—
—
—
0
0
16
132
1.21
0.25
1.3
1.1
155.91
230.62
mg/l
2.88
11
116
15
123
1.22
0.25
1.0
1.1
8.43
12.85
u/ml
—
6
62
124
1311
0.94
0.25
1.3
1.3
—
—
—
0
0
43
476
0.90
0.25
1.0
1.3
—
—
—
0
0
9
76
1.19
0.24
1.2
1.2
7.22
7.91
mm/h
—
9
76
107
1008
1.07
0.24
3.1
2.6
71.01
73.12
e9/l
0.27
80
705
58
533
1.09
0.23
1.2
1.3
4.00
12.26
u/ml
—
5
87
25
218
1.15
0.23
1.3
1.2
—
—
—
0
0
23
264
0.87
0.23
2.4
1.7
—
—
—
0
0
10
125
0.80
0.23
2.4
2.5
53.80
24.83
mg/l
—
5
87
5
39
1.28
0.23
1.6
1.2
—
—
—
0
0
107
1132
0.94
0.22
2.8
3.3
84.24
76.58
ng/l
0.27
88
981
7
91
0.77
0.22
1.3
1.5
64.86
95.14
ng/l
—
7
91
293
2841
1.04
0.22
2.7
2.7
2.45
2.45
mmol/l
0.12
261
2550
5
41
1.22
0.22
1.2
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
48.45
—
0
11
0
12
0.00
0.21
0.0
4.8
—
7.50
—
0
12
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
29
258
1.13
0.21
1.0
1.0
0.57
0.11
u/ml
—
5
75
19
219
0.87
0.20
3.0
2.6
6.62
7.33
mmol/l
0.64
19
212
97
1025
0.94
0.20
4.2
2.9
66.07
66.99
g/l
0.72
85
943
0
14
0.00
0.20
0.0
1.2
—
2.51
—
0
9
123
1290
0.95
0.20
7.1
7.0
0.93
1.00
mmol/l
0.06
98
1068
12
144
0.83
0.20
1.3
1.4
0.41
0.36
g/l
—
6
111
12
144
0.83
0.20
1.3
1.4
6.53
6.54
g/l
—
6
111
12
144
0.83
0.20
1.3
1.4
2.59
2.98
g/l
—
6
110
25
222
1.13
0.19
2.4
2.2
26.80
32.49
umol/l
1.14
25
205
21
184
1.14
0.19
3.3
5.9
346.19
376.40
umol/l
0.38
16
157
124
1297
0.95
0.19
1.4
1.6
3.51
3.40
mmol/l
0.51
81
852
16
137
1.17
0.19
1.3
1.1
25.20
36.81
mg/l
—
10
116
6
53
1.13
0.18
1.3
1.9
28.33
28.48
%
—
6
48
6
53
1.13
0.18
1.0
1.1
—
481.79
—
0
14
12
100
1.20
0.18
2.0
1.2
0.50
0.64
ratio
—
5
60
1258
12653
0.97
0.17
6.5
5.7
38.52
37.93
mmol/mol
1.74
1168
11884
7
61
1.15
0.17
4.1
2.6
23.13
150.23
ug/l
—
7
54
7
61
1.15
0.17
1.6
1.4
113.91
133.77
nmol/l
—
7
61
22
195
1.13
0.17
1.5
1.3
—
—
—
0
0
77
814
0.94
0.17
2.5
2.2
7.34
6.05
ug/l
0.16
69
723
5
70
0.71
0.16
1.6
1.5
—
4.46
—
0
13
40
433
0.92
0.16
1.2
1.3
—
—
—
0
0
608
6167
0.98
0.16
2.0
2.0
98.06
98.98
pmol/l
0.16
295
3067
235
2415
0.97
0.16
4.2
3.4
25.17
330.25
ng/l
6.67
133
1617
33
302
1.09
0.16
1.0
1.0
1.35
4.49
u/ml
2.25
13
144
37
341
1.09
0.16
1.0
1.1
1.51
1.49
u/ml
—
10
166
6
79
0.76
0.15
2.2
1.5
71.50
72.53
umol/l
—
6
79
25
276
0.90
0.15
3.8
3.7
—
—
—
0
0
454
4469
1.02
0.14
5.3
6.1
—
—
—
0
0
109
1133
0.96
0.14
2.3
2.5
18.21
23.14
au/ml
0.41
14
135
12
139
0.86
0.14
3.0
2.8
—
—
—
0
0
58
548
1.06
0.14
1.8
1.5
0.28
0.27
mg/l
0.06
18
208
8
96
0.83
0.13
1.3
1.5
1.45
1.15
promille
—
8
73
11
128
0.86
0.13
1.0
1.2
—
—
—
0
0
11
94
1.17
0.13
1.4
1.2
—
—
—
0
0
22
242
0.91
0.13
1.0
1.0
—
—
—
0
0
35
375
0.93
0.12
6.9
3.9
34.37
51.69
mg/l
0.70
30
329
140
1441
0.97
0.12
1.2
1.2
—
—
—
0
0
35
374
0.93
0.11
6.9
3.9
36.09
39.84
mg/l
0.20
30
330
60
572
1.05
0.11
1.8
2.2
—
—
—
0
0
126
1297
0.97
0.11
7.0
7.1
7.42
7.42
ph
0.46
72
706
10
86
1.16
0.11
1.2
1.1
—
6.70
u/ml
—
0
10
136
1397
0.97
0.10
1.5
1.4
—
—
—
0
0
16
144
1.11
0.10
1.1
1.3
—
—
—
0
0
238
2336
1.02
0.10
2.9
2.7
0.74
1.14
e6/l
2.12
130
1154
727
7211
1.02
0.10
2.5
2.5
78.00
78.12
nmol/l
0.04
667
6596
166
1696
0.98
0.09
1.6
1.8
3.29
3.24
ratio
0.18
120
1241
6
54
1.11
0.09
2.8
2.2
15.08
16.44
%
—
6
54
6
55
1.09
0.09
1.3
1.9
17.17
8.44
%
—
6
50
6
58
1.03
0.08
1.7
1.7
—
—
—
0
0
5
63
0.79
0.08
2.4
2.0
8.26
8.90
mmol/l
—
5
63
7
66
1.06
0.08
2.0
3.9
—
—
—
0
0
67
648
1.04
0.07
1.5
1.6
17.25
12.83
u/ml
0.13
13
141
18
166
1.09
0.07
1.7
1.3
—
—
—
0
0
8
76
1.05
0.07
2.0
3.6
—
—
—
0
0
76
739
1.03
0.07
1.3
1.3
219.08
241.82
miu/ml
0.23
37
371
8
92
0.87
0.06
1.5
1.3
—
—
—
0
0
362
3656
0.99
0.06
3.2
2.1
—
—
—
0
0
8
94
0.85
0.06
1.0
1.2
6.08
6.47
mmol/l
—
8
86
71
730
0.97
0.06
1.6
1.9
6.67
7.17
iu/ml
0.08
20
165
13
142
0.91
0.06
1.3
1.4
—
—
—
0
0
110
1122
0.98
0.06
7.2
7.5
95.92
96.00
%
0.04
105
1092
68
698
0.97
0.05
4.0
3.3
7.42
7.42
ph
0.07
60
583
10
90
1.11
0.05
1.4
1.1
36.70
35.18
mmol/l
—
10
82
85
869
0.98
0.05
2.3
2.1
—
—
—
0
0
15
139
1.08
0.05
1.3
1.1
100.87
107.98
pmol/l
0.34
15
139
34
327
1.04
0.05
1.0
1.1
—
—
—
0
0
73
714
1.02
0.04
1.4
1.8
—
—
—
0
0
42
433
0.97
0.04
2.9
3.6
290.75
653.49
u/ml
0.53
35
378
78
766
1.02
0.03
1.4
1.7
—
—
—
0
0
34
330
1.03
0.03
6.7
3.7
1.41
3.19
ratio
0.85
22
188
15
142
1.06
0.02
9.1
7.0
13.65
12.46
mg/l
0.47
15
134
144
1427
1.01
0.02
2.2
2.3
36.06
37.73
u/l
0.09
118
1187
63
620
1.02
0.02
1.5
1.6
—
—
—
0
0
78
770
1.01
0.02
1.4
1.7
—
—
—
0
0
25
258
0.97
0.02
1.1
1.2
—
—
—
0
0
11
103
1.07
0.02
1.1
1.1
—
—
—
0
0
32
328
0.98
0.01
1.6
1.7
4890.35
10303.33
e6/l
1.31
20
230
82
812
1.01
0.01
3.2
2.9
142.06
144.36
ng/l
0.03
70
747
150
1492
1.01
0.01
1.2
1.2
95.11
146.76
u/ml
1.12
46
577
133
1323
1.01
0.00
3.4
4.3
77.28
10.76
ug/l
0.48
105
1049
37
376
0.98
0.00
1.1
1.2
—
—
—
0
0
77
764
1.01
0.00
1.4
1.7
—
—
—
0
0
10
99
1.01
0.00
1.1
1.1
1624.30
1479.16
miu/ml
—
10
99
10
99
1.01
0.00
1.0
1.1
—
—
—
0
0
64
643
1.00
0.00
1.1
1.1
—
—
—
0
0
35
355
0.99
0.00
2.6
3.5
1.22
1.36
mmol/l
0.58
35
350
76
755
1.01
0.00
1.4
1.7
—
—
—
0
0
122
1225
1.00
0.00
2.9
2.2
0.22
0.21
g/l
0.07
115
1142
21
205
1.02
0.00
1.1
1.1
—
—
—
0
0
13
125
1.04
0.00
1.1
1.1
—
—
u/ml
—
0
0
12
125
0.96
0.00
1.8
1.8
—
—
—
0
0
10
105
0.95
0.00
2.5
3.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
3.09
—
0
8
0
7
0.00
0.00
0.0
1.1
—
69.31
—
0
7
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
340.29
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
34.44
—
0
5
5
59
0.85
-0.00
2.8
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
8102.50
—
0
6
9
90
1.00
-0.00
1.6
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
4.67
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
195.89
—
0
9
0
6
0.00
-0.00
0.0
1.8
—
322.17
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
169.60
—
0
5
5
57
0.88
-0.00
1.8
2.0
50.02
43.89
ug/l
—
5
57
6
65
0.92
-0.00
1.0
1.1
244.50
412.85
u/l
—
6
59
7
70
1.00
-0.00
2.1
1.4
28.00
30.10
umol/l
—
7
63
8
84
0.95
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_MATERN_CARE_CERVICAL_INCOMPETENCE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_MATERN_CARE_CERVICAL_INCOMPETENCE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_MATERN_CARE_CERVICAL_INCOMPETENCE – Maternal care for cervical incompetence

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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