No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
625 |
4. Check minimum number of eventsNone |
625 |
5. Include endpointsNone |
625 |
6. Filter based on genotype QC (FinnGen only) |
547 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Hypotension due to drugs
based on the number of shared cases.
Similar with more cases:
- Hypotension
- Other CVD (FINNGEN)
- Other CVD
- Cardiovascular diseases (excluding rheumatic etc)
- Cardiovascular diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4146 | 2120 | 2001 |
| Only index persons | 3614 | 1853 | 1761 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.06 |
| Only index persons | 0.07 | 0.07 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 77.94 | 80.37 | 75.41 |
| Only index persons | 77.93 | 80.44 | 75.30 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 547 | 215 | 332 |
| Unadjusted period prevalence (%) | 0.12 | 0.08 | 0.15 |
| Median age at first event (years) | 74.38 | 73.52 | 74.93 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 562
- Matched controls
- 5620
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I95.2
ICD-10 Finland
Hypotension due to drugs
+∞
307.7
562
11
I95.9
ICD-10 Finland
Hypotension, unspecified
10.2
47.0
55
59
R07.4
ICD-10 Finland
Chest pain, unspecified
3.4
43.7
265
1175
C01DA14
ATC
isosorbide mononitrate; oral
3.5
43.6
231
943
C03CA01
ATC
furosemide; systemic
3.4
42.9
359
1923
I50.9
ICD-10 Finland
Heart failure, unspecified
3.4
41.4
225
927
R55
ICD-10 Finland
Syncope and collapse
3.8
40.5
153
498
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.0
36.5
269
1304
R53
ICD-10 Finland
Malaise and fatigue
3.0
35.0
234
1069
T36
ICD-10 Finland
Poisoning by systemic antibiotics
7.6
34.0
50
71
I95.1
ICD-10 Finland
Orthostatic hypotension
4.9
32.9
79
181
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.2
32.7
97
263
C07AB07
ATC
bisoprolol; oral
3.0
30.9
407
2611
R42
ICD-10 Finland
Dizziness and giddiness
2.9
30.3
217
1014
C03DA01
ATC
spironolactone; oral
3.1
28.1
147
575
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.7
28.1
264
1405
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.1
27.8
148
584
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.2
27.7
132
488
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
27.6
371
2343
R06.0
ICD-10 Finland
Dyspnoea
2.7
27.4
239
1223
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.7
27.3
218
1067
N05AH04
ATC
quetiapine; oral
3.1
27.3
143
559
AN1
HP
Coronary angiography
3.1
25.7
132
509
AA1AD
NOMESCO Finland
CT of head and brain
2.5
25.5
258
1407
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.6
25.0
209
1039
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
3.0
24.7
135
538
E86
ICD-10 Finland
Volume depletion
5.5
24.3
49
96
205
Kela drug reimbursment
Chronic hypertension
2.5
24.2
257
1423
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.5
23.9
220
1139
I50.0
ICD-10 Finland
Congestive heart failure
3.1
23.8
118
444
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
8.4
23.2
31
39
B01AC04
ATC
clopidogrel; oral
2.6
22.7
176
837
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.4
21.8
240
1336
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
21.5
208
1092
I20.09
ICD-10 Finland
Unstable angina
3.5
21.1
81
260
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
3.3
20.8
88
300
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
20.3
217
1185
I10
ICD-10 Finland
Essential (primary) hypertension
2.6
20.2
443
3283
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
20.1
124
522
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.4
19.4
170
847
SPAT1254
SPAT
Administration of medicine
2.6
19.4
136
610
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.3
19.3
213
1173
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
19.2
253
1500
N03AG01
ATC
valproic acid; systemic, rectal
4.1
19.1
55
144
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
18.8
158
772
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.1
18.4
85
305
SPAT1301
SPAT
No procedures
2.2
17.6
227
1324
N05AX12
ATC
aripiprazole; systemic
7.0
17.6
27
40
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
3.1
17.4
78
274
K59.09
ICD-10 Finland
Constipation, unspecified
3.2
17.3
76
264
SPAT1263
SPAT
Sampling
2.1
17.1
268
1681
I25.2
ICD-10 Finland
Old myocardial infarction
2.9
17.1
91
353
C08CA01
ATC
amlodipine; oral
2.1
17.0
298
1949
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.2
16.9
209
1194
I50.1
ICD-10 Finland
Left ventricular failure
3.2
16.8
72
246
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.7
16.5
56
165
C07AB02
ATC
metoprolol; systemic
2.2
16.5
182
992
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
16.2
115
516
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.6
16.1
111
491
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
15.8
137
673
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.6
15.6
99
420
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.7
15.5
51
147
N05AH03
ATC
olanzapine; systemic
3.9
15.5
47
128
J01DB01
ATC
cefalexin; oral
2.5
15.5
468
3727
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.1
15.4
205
1198
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.1
15.3
203
1183
A02BC02
ATC
pantoprazole; systemic
2.2
15.3
413
3128
N05AA02
ATC
levomepromazine; systemic
4.3
15.2
41
102
A04
ICPC
Weakness/tiredness general
2.4
15.0
126
608
N06AX11
ATC
mirtazapine; oral
2.1
15.0
218
1312
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
15.0
227
1389
Z02.7
ICD-10 Finland
Issue of medical certificate
3.2
14.9
65
224
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.7
14.9
87
353
207
Kela drug reimbursment
Chronic arrhythmias
2.2
14.7
157
838
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.3
14.7
129
635
B01AA03
ATC
warfarin; systemic
2.1
14.6
193
1121
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.7
14.5
84
339
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.9
14.4
75
286
C10AA01
ATC
simvastatin; oral
2.0
14.4
324
2270
N02BE01
ATC
paracetamol; systemic, rectal
3.3
14.3
517
4373
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.2
14.3
160
870
ZXD05
NOMESCO Finland
Urgent procedure
2.1
14.3
197
1160
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
14.1
178
1012
N30.0
ICD-10 Finland
Acute cystitis
2.3
14.0
119
577
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.3
14.0
135
691
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.6
13.8
46
134
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.9
13.7
71
270
N05AX08
ATC
risperidone; systemic
2.6
13.7
90
387
A06AD11
ATC
lactulose; oral
2.2
13.4
142
752
R07.3
ICD-10 Finland
Other chest pain
2.6
13.4
86
365
M04AA01
ATC
allopurinol; systemic
2.2
13.3
128
653
WX892
NOMESCO Finland
Monitored bed care
2.9
13.3
69
263
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.3
13.1
52
169
N05BA04
ATC
oxazepam; oral
2.1
13.1
175
1013
T90
ICPC
Diabetes non-insulin dependent
2.0
13.0
179
1048
C09AA05
ATC
ramipril; oral
2.0
12.9
209
1294
SPAT1240
SPAT
Therapeutic discussion
3.3
12.9
51
166
P76
ICPC
Depressive disorder
4.2
12.8
35
88
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
5.1
12.8
27
55
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
3.1
12.7
56
194
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
12.7
130
679
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.1
12.6
143
777
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
12.4
119
604
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
2.5
12.4
89
398
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.8
12.4
39
109
L28
ICPC
Limited function/disability (L)
2.1
12.3
160
913
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.5
12.3
86
380
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.1
12.3
154
868
N03AX16
ATC
[U] pregabalin
2.1
12.2
149
831
R03AC02
ATC
salbutamol; inhalant
1.9
12.1
302
2142
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
12.1
131
698
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
5.8
12.0
22
39
H02AB06
ATC
prednisolone; systemic
1.9
11.9
293
2067
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
15.1
11.9
19
13
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.8
11.8
62
237
A10BK01
ATC
dapagliflozin; oral
2.8
11.8
64
249
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.2
11.8
108
538
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
11.8
129
690
A28
ICPC
Limited function/disability NOS
2.0
11.7
169
999
A02BC05
ATC
esomeprazole; systemic
1.9
11.6
238
1582
P29
ICPC
Psychological sympt/compl other
3.5
11.4
40
120
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.5
11.4
80
354
A11
ICPC
Chest pain NOS
2.5
11.4
75
322
N06AB10
ATC
escitalopram; oral
2.2
11.4
104
517
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.5
11.4
28
65
SPAT1216
SPAT
Assessment of functional ability
2.1
11.3
133
730
K29
ICPC
Cardiovascular sympt/complt other
3.3
11.2
43
137
N06AX16
ATC
venlafaxine; oral
2.5
11.2
76
331
C01AA05
ATC
digoxin; systemic
2.3
11.1
98
479
C10AA05
ATC
atorvastatin; oral
1.8
11.1
284
2014
I20.00
ICD-10 Finland
Unstable angina
3.4
11.0
41
128
K59.0
ICD-10 Finland
Constipation
2.8
11.0
59
228
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.3
11.0
29
71
B01AF02
ATC
apixaban; oral
2.1
11.0
122
654
SPAT1262
SPAT
Handing over of treatment supplies
2.1
11.0
128
699
G47.3
ICD-10 Finland
Sleep apnoea
2.0
11.0
141
798
N06AA09
ATC
amitriptyline; systemic
2.6
11.0
70
296
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.2
10.8
100
498
H02AA02
ATC
fludrocortisone; oral
10.9
10.8
20
19
N17
ICPC
Vertigo/dizziness
2.2
10.8
99
491
81
HP
Angiography of the heart and coronary arteries
2.5
10.8
72
311
SPAT1229
SPAT
Assessment of need for aid
2.5
10.7
71
305
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
10.7
202
1298
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
10.6
199
1276
I95.8
ICD-10 Finland
Other hypotension
11.5
10.6
19
17
M10.9
ICD-10 Finland
Gout, unspecified
2.5
10.6
70
301
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.0
10.6
49
175
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
7.9
10.5
23
30
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.4
10.5
76
341
M79.6
ICD-10 Finland
Pain in limb
1.8
10.5
246
1690
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.5
10.5
71
309
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.5
10.5
36
107
R50.9
ICD-10 Finland
Fever, unspecified
2.2
10.4
104
534
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
10.4
61
247
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.5
10.4
71
310
M54.5
ICD-10 Finland
Low back pain
1.9
10.4
198
1276
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
10.4
178
1109
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
10.3
114
609
A46
ICD-10 Finland
Erysipelas
2.1
10.3
117
632
R11
ICD-10 Finland
Nausea and vomiting
2.5
10.2
69
299
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
8.1
10.2
22
28
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.2
10.2
95
475
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.3
10.2
84
399
A08
ICPC
Swelling
2.7
10.1
55
214
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
10.1
114
613
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.1
10.1
42
141
EBA10
NOMESCO Finland
Operative extraction of tooth
2.6
10.1
59
239
N06AB03
ATC
fluoxetine; oral
2.3
10.0
78
361
K78
ICPC
Atrial fibrillation/flutter
2.3
10.0
82
388
E66.8
ICD-10 Finland
Other obesity
3.9
10.0
30
81
SPAT1053
SPAT
Memory test
2.0
10.0
131
745
N06AX26
ATC
vortioxetine; oral
3.1
9.9
42
142
F31.8
ICD-10 Finland
Other bipolar affective disorders
12.5
9.9
17
14
I20.90
ICD-10 Finland
Angina pectoris, unspecified
2.9
9.8
46
165
N03AX12
ATC
[U] gabapentin; oral
2.1
9.8
108
575
R41.0
ICD-10 Finland
Disorientation, unspecified
3.2
9.8
39
127
SPAT1312
SPAT
General health counselling
1.9
9.7
174
1095
I48.2
ICD-10 Finland
Chronic atrial fibrillation
2.7
9.7
56
225
J01MA12
ATC
levofloxacin; systemic
1.9
9.7
137
798
F29
ICD-10 Finland
Unspecified nonorganic psychosis
4.4
9.7
24
56
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
9.7
109
586
S97
ICPC
Chronic ulcer skin
2.5
9.7
66
288
N05AF03
ATC
chlorprothixene; systemic
4.9
9.6
21
44
SPAT1234
SPAT
Support of social functional capacity
2.7
9.5
53
209
N05AB03
ATC
perphenazine; systemic, rectal
4.0
9.5
27
70
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.1
9.5
40
135
E87.6
ICD-10 Finland
Hypokalaemia
3.4
9.5
34
104
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.5
9.5
33
99
R51.80
ICD-10 Finland
Headache
2.2
9.3
86
427
L17
ICPC
Foot/toe symptom/complaint
1.8
9.3
178
1141
N05BA12
ATC
alprazolam; oral
2.4
9.3
66
293
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
9.3
213
1441
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
9.2
82
401
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.0
9.2
40
138
R02
ICPC
Shortness of breath/dyspnoea
2.1
9.1
96
502
N05BA01
ATC
diazepam; systemic, rectal
2.2
9.1
87
439
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
9.0
231
1608
N03AX09
ATC
lamotrigine; oral
3.8
9.0
27
73
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
9.0
220
1514
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
8.9
186
1220
N02AX02
ATC
tramadol; systemic, rectal
1.7
8.9
260
1876
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
8.9
270
1970
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
10.9
8.8
16
15
M54.4
ICD-10 Finland
Lumbago with sciatica
2.1
8.8
98
523
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
8.8
87
444
R39.1
ICD-10 Finland
Other difficulties with micturition
3.3
8.8
33
104
N02AA05
ATC
oxycodone; systemic
1.8
8.8
151
935
P03
ICPC
Feeling depressed
2.8
8.7
43
159
C09CA03
ATC
valsartan; oral
2.3
8.7
72
342
E66.00
ICD-10 Finland
Metabolic syndrome
3.0
8.7
39
137
N06AB04
ATC
citalopram; systemic
1.9
8.7
125
731
C07AG02
ATC
carvedilol; oral
2.5
8.6
58
251
M10
ICD-10 Finland
Gout
2.9
8.6
40
143
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.9
8.6
40
143
A10BH01
ATC
sitagliptin; oral
2.2
8.6
76
371
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.7
8.6
47
184
E87.5
ICD-10 Finland
Hyperkalaemia
3.8
8.5
26
71
R5140
NOMESCO Finland
Monitoring the use of the aid
2.2
8.5
79
393
N05CF01
ATC
zopiclone; oral
1.7
8.5
208
1426
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.3
8.5
67
312
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
8.4
131
784
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.7
8.4
45
174
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
3.2
8.4
33
107
I42.0
ICD-10 Finland
Dilated cardiomyopathy
3.3
8.3
31
97
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.7
8.3
47
187
XF402
NOMESCO Finland
ECG with work load test
2.1
8.3
80
404
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
8.3
88
461
XF600
NOMESCO Finland
Bloodpressure measurement
2.5
8.3
52
218
C03AA03
ATC
hydrochlorothiazide; oral
2.2
8.1
75
372
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
8.1
241
1734
F10.24
ICD-10 Finland
Alcohol depence active use
8.3
8.1
17
21
J01CA04
ATC
amoxicillin; systemic
1.8
8.1
422
3525
A10AE04
ATC
insulin glargine; parenteral
2.1
8.1
77
387
C07AA07
ATC
sotalol; systemic
2.7
8.1
43
166
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.9
8.1
114
661
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
2.4
8.0
54
234
L03
ICPC
Low back symptom/complaint
1.8
8.0
155
992
82
HP
Single vessel balloon catheter extension
3.3
7.9
29
90
A10BA02
ATC
metformin; oral
1.7
7.9
194
1326
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
2.7
7.8
41
157
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.3
7.8
29
91
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.5
7.8
50
212
UJF32
NOMESCO Finland
Coloscopy
1.7
7.8
167
1099
N06AX21
ATC
duloxetine; oral
2.2
7.8
65
310
H02AB07
ATC
prednisone; oral
2.0
7.7
91
495
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
2.7
7.7
43
170
R04.0
ICD-10 Finland
Epistaxis
2.2
7.7
64
305
N18.8
ICD-10 Finland
Other chronic renal failure
3.6
7.6
25
72
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.7
7.6
41
159
A13
ICPC
Concern/fear medical treatment
3.9
7.6
22
58
AN4
HP
Balloon angioplasty and drug eluding stent
3.0
7.6
33
114
A12BA01
ATC
potassium chloride; oral
2.5
7.5
50
215
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.7
7.5
41
160
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
7.5
172
1152
A10AB05
ATC
insulin aspart; parenteral
2.3
7.4
59
275
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
7.8
7.4
16
21
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.8
7.4
22
59
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
7.4
75
386
B81
ICPC
Anaemia vit B12/folate deficiency
2.8
7.3
36
133
I25
ICD-10 Finland
Chronic ischaemic heart disease
2.5
7.3
47
199
Z3231
NOMESCO Finland
Registered nurse
1.7
7.3
165
1098
S06.0
ICD-10 Finland
Concussion
2.1
7.3
73
374
K08.3
ICD-10 Finland
Retained dental root
2.3
7.3
55
251
F20.9
ICD-10 Finland
Schizophrenia, unspecified
5.9
7.3
19
33
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.0
7.2
31
106
G04CA02
ATC
tamsulosin; oral
1.7
7.2
200
1406
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.8
7.2
35
129
ZXE00
NOMESCO Finland
One hour or less
1.6
7.1
213
1523
SPAT1307
SPAT
Psychosocial counselling and guidance
3.7
7.1
22
61
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
7.1
87
480
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.3
7.1
18
43
N30.9
ICD-10 Finland
Cystitis, unspecified
2.4
7.1
48
209
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.4
7.0
25
76
P15
ICPC
Chronic alcohol abuse
4.0
7.0
20
52
E66.01
ICD-10 Finland
Obesity due to excess calories
2.5
7.0
43
178
I50
ICD-10 Finland
Heart failure
2.7
7.0
37
142
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
7.0
58
275
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.7
7.0
38
148
G44.2
ICD-10 Finland
Tension-type headache
2.1
7.0
69
351
C09DX01
ATC
valsartan, amlodipine and hydrochlorothiazide; oral
4.5
7.0
17
39
F03
ICD-10 Finland
Unspecified dementia
2.3
6.9
51
230
J01FF01
ATC
clindamycin; systemic
1.7
6.9
154
1018
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
2.9
6.9
33
120
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.9
6.9
90
507
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
6.9
83
455
D09
ICPC
Nausea
3.1
6.9
28
93
C01BD01
ATC
amiodarone; systemic
3.1
6.9
28
93
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.1
6.9
28
93
C02AC05
ATC
moxonidine; oral
2.6
6.8
40
162
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
5.8
6.8
18
32
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.2
6.8
58
279
K07
ICPC
Swollen ankles/oedema
2.4
6.8
45
194
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
6.7
64
321
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
6.7
43
182
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.4
6.7
46
201
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
6.7
97
565
N05AH02
ATC
clozapine; systemic
6.6
6.7
16
25
I20.80
ICD-10 Finland
Other angina pectoris no detected stenosis of coronary artery
4.1
6.7
18
45
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.0
6.7
75
401
IGY99
NOMESCO Finland
Other psychiatric treatment contact
7.9
6.6
14
18
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.5
6.6
42
177
FN1BT
NOMESCO Finland
Extensive endovascular dilatation of coronary (PTCA) arteries
3.4
6.6
23
69
TKC20
NOMESCO Finland
Catheterisation of bladder
2.1
6.6
61
303
C02DE02, ,
ATC
3.9
6.6
19
50
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.0
6.6
72
381
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
2.5
6.5
42
178
S18
ICPC
Laceration/cut
1.6
6.5
269
2066
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.9
6.5
89
508
AN3
HP
Balloon angioplasty and metallic stent
3.0
6.5
28
96
P72
ICPC
Schizophrenia
5.4
6.5
18
34
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
6.5
139
908
AN2
HP
Balloon angioplasty, including several vessels
3.1
6.5
27
91
N05BA06
ATC
lorazepam; systemic, sublingual
2.4
6.4
44
192
SPAT1101
SPAT
Orthostatic test
2.5
6.4
40
167
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.4
6.4
46
205
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
6.4
75
406
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
3.1
6.4
26
86
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
6.4
188
1331
XF404
NOMESCO Finland
Ambulatory ECG
2.0
6.4
67
349
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.0
6.4
78
429
C09AA02
ATC
enalapril; systemic
1.7
6.4
140
921
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
6.1
6.3
16
27
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
9.4
6.3
12
13
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
9.4
6.3
12
13
P20
ICPC
Memory disturbance
1.7
6.3
120
758
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.3
6.3
48
220
A29
ICPC
General symptom/complaint other
1.8
6.3
95
560
KMAK, ,
NOMESCO Finland
1.6
6.3
224
1660
I84.0
ICD-10 Finland
Internal thrombosed hemorrhoids
18.3
6.3
9
5
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.3
6.3
49
227
SPAT1255
SPAT
Intravenous administration of medicine
2.3
6.3
49
227
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.7
6.2
33
127
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.0
6.2
27
93
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.7
6.2
34
133
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
2.3
6.2
48
221
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.6
6.2
35
139
SPAT1246
SPAT
Screening of depression or other psychiatric problem
3.6
6.2
20
57
P99
ICPC
Psychological disorders other
4.0
6.2
17
43
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.3
6.2
46
209
B01AB05
ATC
enoxaparin; parenteral
1.6
6.1
190
1361
SPAT1070
SPAT
Doppler ultrasound examination of blood flow in arteries of lower extremity
4.2
6.1
16
39
PD5AD
NOMESCO Finland
CT of aorta
3.2
6.1
24
78
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.2
6.1
53
257
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
6.1
230
1725
R00.1
ICD-10 Finland
Bradycardia, unspecified
2.5
6.1
36
147
J01MA02
ATC
ciprofloxacin; systemic
1.6
6.0
237
1791
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
2.8
6.0
29
106
R03BB04
ATC
tiotropium bromide; inhalant
1.9
6.0
81
460
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
4.0
6.0
17
44
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.9
6.0
27
95
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.9
6.0
27
95
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
2.8
6.0
30
112
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
6.0
102
623
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
337
1912
2.90
33.20
5.4
3.5
2615.93
1808.70
ng/l
1.42
312
1680
282
1467
2.85
32.62
2.9
2.3
2.92
3.08
mg/l
0.51
243
1253
297
1602
2.81
31.82
3.4
2.2
178.90
272.82
u/l
0.92
284
1513
410
2650
3.02
30.49
30.5
19.3
1.47
1.36
inr
2.70
372
2242
409
2643
3.01
30.37
7.7
6.7
13.29
12.45
umol/l
0.48
394
2519
378
2356
2.85
29.81
6.4
5.1
33.98
34.60
g/l
1.35
345
2196
207
964
2.82
28.86
3.1
2.6
11.85
12.13
umol/l
0.18
193
901
345
2090
2.69
28.14
3.9
3.1
146.13
149.11
ug/l
0.09
314
1911
212
1030
2.70
26.87
2.7
1.9
—
—
—
0
0
193
897
2.75
26.67
3.2
2.6
2.28
2.23
g/l
0.59
176
831
174
772
2.82
26.24
2.6
1.9
—
—
—
0
0
345
2144
2.58
25.83
9.0
4.5
43.64
56.37
ng/l
0.34
295
1715
132
509
3.08
25.65
8.0
7.0
10.85
11.38
mmol/l
0.35
124
484
182
840
2.73
25.30
3.0
2.6
20.98
21.86
%
0.36
169
785
279
1584
2.51
25.17
3.6
2.6
55.21
112.21
u/l
0.59
262
1481
130
504
3.05
24.97
3.8
2.7
8.38
7.01
ug/l
0.26
110
445
187
892
2.64
24.17
4.1
3.3
0.79
0.82
mmol/l
2.18
171
844
425
2973
2.76
24.06
10.5
5.4
7.02
6.88
mmol/l
0.67
415
2847
163
732
2.73
23.71
6.5
5.5
1.03
1.03
mmol/l
0.01
153
677
155
728
2.56
20.20
2.7
2.0
—
—
—
0
0
432
3178
2.55
19.74
7.9
5.4
12.17
2977.67
e6/l
—
6
70
379
2645
2.33
19.32
12.5
7.4
1.20
1.21
mmol/l
1.15
339
2266
198
1061
2.34
19.14
1.9
1.8
1113.32
1200.74
nmol/l
0.64
154
807
249
1485
2.22
18.44
4.0
3.3
43.06
36.14
u/l
0.33
232
1403
464
3579
2.70
18.35
11.8
8.5
90.83
81.34
u/l
1.88
436
3377
347
2380
2.20
17.80
12.3
6.6
1.20
1.21
mmol/l
1.90
324
2189
130
595
2.54
17.65
5.4
3.7
2.28
1.86
mmol/l
0.57
113
495
83
301
3.06
17.57
1.8
1.5
—
—
—
0
0
197
1094
2.23
17.15
8.1
4.4
280.98
337.31
ng/l
0.14
172
946
115
504
2.61
17.03
4.7
3.4
255.76
263.10
ng/l
0.06
103
467
146
716
2.40
17.00
10.6
7.1
5.27
5.10
kpa
0.95
140
694
146
717
2.40
16.94
10.7
7.1
11.27
11.62
kpa
0.29
140
695
336
2311
2.13
16.65
2.9
2.3
94.09
93.84
pmol/l
0.03
206
1247
143
705
2.38
16.39
10.5
7.2
1.41
1.08
mmol/l
0.44
120
582
135
652
2.41
16.19
11.0
7.4
95.50
94.98
%
0.59
130
636
128
615
2.40
15.46
5.6
3.7
6.04
5.78
kpa
1.67
123
592
272
1764
2.05
15.38
5.2
3.8
29.31
116.04
e6/l
1.58
227
1377
260
1660
2.05
15.34
2.2
1.8
18.33
20.17
nmol/l
1.14
227
1398
100
444
2.52
14.26
2.1
2.0
359.35
391.58
nmol/l
0.87
92
407
361
2646
2.02
13.91
14.0
9.4
4.52
4.37
e9/l
0.52
326
2300
207
1262
2.01
13.47
3.7
2.8
4.62
4.93
e6/l
0.15
193
1152
266
1769
1.96
13.46
3.1
3.5
2.33
2.35
mmol/l
1.32
239
1593
237
1517
1.97
13.40
5.2
3.6
0.56
0.61
e6/l
0.09
192
1144
109
520
2.36
13.23
4.8
3.0
4.09
4.34
kpa
0.92
104
498
57
197
3.11
13.02
1.3
1.3
—
—
—
0
0
340
2473
1.95
13.01
6.1
4.5
0.00
0.00
estimate
-0.00
71
552
51
166
3.28
12.86
2.0
1.4
0.39
0.31
mg/l
0.40
26
65
342
2500
1.94
12.80
6.1
4.5
0.00
6.09
estimate
0.80
70
575
195
1184
1.99
12.69
6.2
4.3
82.17
83.06
%
0.17
190
1169
91
410
2.46
12.50
1.7
1.7
—
—
—
0
0
343
2522
1.92
12.47
6.2
4.5
0.06
0.56
estimate
0.43
66
540
175
1030
2.02
12.39
1.9
1.7
1.50
1.62
mg/l
0.18
144
840
87
386
2.48
12.35
2.6
1.7
1.75
1.62
%
0.43
70
324
253
1695
1.90
12.16
3.8
3.4
7.04
7.41
mmol/l
0.71
210
1402
295
2078
1.88
12.11
3.0
2.4
76.65
78.90
nmol/l
0.63
260
1834
278
1925
1.88
12.01
6.3
4.4
385.35
133.93
e6/l
0.69
228
1420
162
938
2.02
11.95
4.7
3.3
1.18
1.20
e6/l
0.02
101
521
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
54
193
2.99
11.63
2.4
2.4
0.40
0.36
iu/ml
0.25
35
103
104
516
2.25
11.41
2.5
2.2
0.21
0.20
g/l
0.39
92
474
93
442
2.32
11.29
3.0
2.5
32.44
33.14
u/l
0.05
84
367
358
2726
1.86
11.06
5.3
3.4
82.32
55.63
u/l
2.33
338
2543
186
1157
1.91
10.99
2.1
1.9
63333778.61
6032184.16
pmol/l
0.43
150
945
303
2197
1.82
10.92
3.5
3.0
—
—
estimate
—
0
0
100
497
2.23
10.90
3.2
2.9
65.59
65.76
g/l
0.08
89
457
251
1723
1.83
10.81
4.5
4.2
10.35
9.93
mg/mmol
0.07
167
1115
108
559
2.15
10.63
3.0
2.9
8.82
8.75
umol/l
0.02
100
498
88
420
2.30
10.55
4.0
3.9
110.42
89.81
ng/l
1.05
77
365
150
879
1.96
10.52
4.7
3.5
2.47
1.89
e6/l
0.34
90
462
498
4307
2.37
9.96
39.7
20.0
25.04
27.65
mg/l
1.52
473
3691
198
1290
1.83
9.92
3.8
3.0
374.73
364.13
umol/l
0.60
165
1124
403
3256
1.84
9.49
5.2
4.1
15.02
15.06
pmol/l
0.11
372
2910
183
1181
1.81
9.36
3.0
2.7
—
—
—
0
0
73
339
2.33
9.29
3.4
4.0
0.83
1.89
mmol/l
0.91
56
259
211
1448
1.73
8.60
6.4
4.5
0.00
0.00
estimate
0.50
64
504
78
385
2.19
8.58
2.3
1.7
—
—
—
0
0
172
1115
1.78
8.54
2.9
3.1
2.46
2.46
mmol/l
0.02
153
987
411
3393
1.79
8.39
6.0
4.5
16.91
14.46
mm/h
1.95
383
3126
170
1108
1.77
8.24
6.5
4.9
1.02
1.02
kg/l
1.41
125
757
461
3953
1.92
8.17
7.2
5.2
2.00
2.04
mu/l
0.23
425
3574
286
2176
1.64
7.60
3.2
2.5
—
—
—
0
0
16
21
7.81
7.43
6.8
2.1
139.14
75.07
umol/l
—
7
14
32
111
3.00
7.29
1.4
1.4
—
—
—
0
0
32
111
3.00
7.29
1.4
1.4
—
—
—
0
0
500
4461
2.10
7.15
51.2
24.5
139.16
139.55
mmol/l
2.25
492
4375
87
479
1.97
7.12
2.8
2.7
0.44
0.65
e6/l
0.40
87
465
500
4468
2.08
7.01
51.9
24.7
4.03
4.02
mmol/l
0.50
490
4378
47
205
2.41
6.88
3.3
2.3
10.26
10.56
g/l
0.21
40
183
139
897
1.73
6.82
1.3
1.2
0.75
1.49
u/ml
1.63
29
239
41
170
2.52
6.69
4.4
3.2
0.73
0.86
nmol/l
1.25
33
144
43
185
2.43
6.49
4.2
3.7
1.36
2.74
ratio
1.69
24
104
46
206
2.34
6.36
4.2
4.0
54.21
56.87
mg/l
0.05
39
175
46
206
2.34
6.36
4.2
4.0
50.22
87.30
mg/l
0.65
39
172
249
1892
1.57
6.26
6.6
4.6
0.00
0.05
estimate
2.28
61
462
501
4528
1.98
6.06
52.0
26.8
93.75
85.72
umol/l
3.20
493
4466
33
131
2.61
5.89
1.3
1.4
—
—
—
0
0
467
4143
1.75
5.84
7.0
5.6
6.35
6.12
mmol/l
2.71
423
3724
93
558
1.80
5.80
11.9
8.7
—
—
—
0
0
58
298
2.06
5.74
4.5
3.3
25.24
25.20
mmol/l
0.03
53
288
45
210
2.24
5.68
4.4
3.3
4.11
4.34
pmol/l
1.20
38
185
28
105
2.75
5.58
1.4
1.6
—
—
—
0
0
491
4453
1.81
5.24
19.7
12.9
26.19
24.88
u/l
0.52
475
4306
20
64
3.20
5.24
1.3
1.3
—
—
—
0
0
108
696
1.68
5.22
3.2
4.0
258.51
248.51
u/l
0.22
100
661
501
4573
1.88
5.22
58.3
30.0
231.29
237.99
e9/l
1.43
490
4475
501
4574
1.88
5.20
58.0
29.8
92.13
91.82
fl
0.66
493
4515
501
4575
1.88
5.18
59.6
30.5
38.34
39.57
%
5.35
493
4512
501
4575
1.88
5.18
58.1
29.9
4.24
4.39
e12/l
8.20
491
4458
501
4576
1.87
5.16
58.7
30.2
127.48
132.57
g/l
11.25
493
4514
458
4085
1.65
5.09
10.1
7.3
42.85
40.57
mmol/mol
4.80
431
3764
51
268
1.99
4.77
2.4
1.8
2.11
2.61
ug/l
0.14
46
235
73
448
1.72
4.20
6.2
4.1
1.21
1.22
mmol/l
1.39
63
388
31
143
2.24
4.07
1.8
1.6
—
—
—
0
0
24
100
2.46
3.94
1.3
1.3
—
—
—
0
0
40
207
2.00
3.93
2.4
1.7
—
—
—
0
0
30
139
2.22
3.90
1.8
1.6
—
—
—
0
0
463
4219
1.55
3.85
7.4
6.2
2.11
2.51
mmol/l
19.74
427
3828
40
210
1.97
3.78
3.9
4.7
23.82
25.12
mmol/l
1.11
35
197
10
20
5.07
3.70
1.1
1.2
27.50
20.67
u/l
—
10
15
436
3934
1.48
3.69
5.6
4.5
1.37
1.26
mmol/l
2.87
399
3533
13
36
3.67
3.51
1.1
1.2
46.31
49.77
u/l
0.14
13
30
60
368
1.71
3.48
1.5
1.5
—
—
—
0
0
27
127
2.18
3.41
1.3
1.2
—
—
—
0
0
28
134
2.15
3.39
1.9
2.5
123.55
113.17
ug/min
0.05
12
78
27
128
2.17
3.35
1.3
1.2
—
—
—
0
0
84
568
1.56
3.32
5.7
3.9
—
—
—
0
0
448
4094
1.46
3.28
6.4
5.3
1.33
1.42
mmol/l
5.09
414
3702
41
229
1.85
3.26
2.3
1.8
—
—
—
0
0
13
39
3.39
3.24
1.0
1.2
—
—
—
0
0
17
66
2.62
3.24
1.6
1.7
—
—
—
0
0
28
137
2.10
3.22
1.6
1.4
292.86
275.78
ug/g
0.15
18
81
14
49
2.90
3.21
1.2
1.2
1.20
1.80
u/ml
—
5
15
24
111
2.21
3.17
1.3
1.2
2.56
6.76
u/ml
—
5
20
450
4124
1.46
3.17
6.4
5.4
3.98
4.38
mmol/l
13.96
418
3771
15
56
2.72
3.08
2.1
2.9
855.47
796.32
mg
0.06
15
56
18
74
2.48
3.07
3.4
2.1
10.94
10.40
mmol/l
0.24
18
74
17
68
2.55
3.07
1.5
1.7
—
—
—
0
0
17
68
2.55
3.07
4.2
3.2
—
856.17
—
0
6
50
304
1.71
3.01
1.4
1.8
1.64
1.57
g/l
0.16
42
279
28
141
2.04
3.00
1.3
1.3
—
—
—
0
0
41
236
1.80
2.98
3.2
3.0
—
—
—
0
0
29
149
2.00
2.95
3.9
3.5
2.18
1.84
index
0.15
17
88
31
164
1.94
2.91
2.3
1.5
—
—
—
0
0
28
143
2.01
2.90
2.1
2.2
126.17
125.36
g/l
0.08
23
112
7
13
5.44
2.87
20.7
10.8
0.52
0.65
mmol/l
—
7
13
31
165
1.93
2.87
1.4
1.3
—
—
—
0
0
376
3372
1.35
2.79
53.7
26.5
329.39
331.33
g/l
3.26
370
3351
5
6
8.39
2.75
1.0
1.2
—
—
—
0
0
25
127
2.01
2.64
2.0
1.5
—
—
—
0
0
13
49
2.69
2.64
1.1
1.1
—
—
—
0
0
249
2120
1.31
2.59
5.7
6.1
2.58
3.72
ug/l
0.85
220
1876
442
4088
1.38
2.52
38.4
19.7
68.27
72.56
ml/min/173m2
3.85
428
3844
9
27
3.37
2.40
3.0
1.8
171.11
87.48
umol/l
—
9
27
29
163
1.82
2.31
1.7
2.0
7.26
9.34
iu/ml
—
7
43
33
194
1.74
2.28
2.2
2.0
40.91
38.32
u/l
0.21
26
172
5
9
5.59
2.21
4.0
1.1
1.18
1.16
mmol/l
—
5
9
93
700
1.39
2.16
1.3
1.3
53.31
36.18
iu/ml
0.28
29
225
10
36
2.81
2.14
4.3
3.3
0.50
0.86
index
—
10
36
6
15
4.03
2.04
1.0
1.1
—
—
—
0
0
21
111
1.93
2.03
2.0
1.5
—
—
—
0
0
21
113
1.89
1.94
1.9
1.5
—
—
—
0
0
6
16
3.78
1.94
1.0
1.1
174.35
215.09
iu/ml
—
6
16
5
12
4.19
1.82
1.0
1.1
—
—
—
0
0
79
597
1.38
1.80
3.8
4.5
3.99
31.96
ug/l
1.37
65
511
7
23
3.07
1.80
1.0
1.1
—
—
—
0
0
7
23
3.07
1.80
1.0
1.1
—
—
—
0
0
28
170
1.68
1.77
4.1
3.5
1.65
1.66
mmol/l
0.03
28
165
25
147
1.73
1.77
4.2
3.5
7.74
7.84
mmol/l
0.05
25
142
9
36
2.52
1.74
1.0
1.2
98.78
89.92
pmol/l
—
9
36
54
385
1.45
1.72
5.6
3.0
54.10
59.02
ml/min/173m2
0.66
31
171
84
647
1.35
1.71
1.4
1.3
39.44
12.46
u/ml
0.75
26
240
7
25
2.82
1.65
1.1
2.3
—
—
—
0
0
7
25
2.82
1.65
2.3
1.6
58.29
58.62
ug/l
—
7
25
6
20
3.02
1.58
1.0
2.3
713.67
934.60
u/ml
—
6
20
17
92
1.87
1.57
1.8
1.9
—
—
—
0
0
12
57
2.13
1.56
1.0
1.0
—
—
—
0
0
196
1703
1.23
1.55
4.9
5.0
22.24
21.57
%
0.24
94
893
159
1352
1.25
1.53
6.1
4.0
0.00
0.09
estimate
0.88
55
436
6
21
2.88
1.51
1.0
1.7
34.32
39.44
g/l
—
6
21
12
59
2.06
1.44
1.4
1.3
—
—
—
0
0
5
16
3.14
1.44
1.2
1.1
6.54
7.60
mmol/l
—
5
16
24
149
1.64
1.43
1.6
1.4
—
—
—
0
0
6
23
2.63
1.37
1.8
1.2
—
—
—
0
0
5
17
2.96
1.36
1.0
1.6
0.63
0.63
mmol/l
—
5
17
9
42
2.16
1.34
1.3
1.2
—
81.83
—
0
6
12
61
1.99
1.33
1.1
1.5
—
—
—
0
0
5
18
2.79
1.28
3.2
3.6
7.60
6.77
ug/l
—
5
18
12
62
1.96
1.28
1.1
1.5
—
—
—
0
0
12
62
1.96
1.28
1.8
1.4
183.32
153.76
au/ml
—
6
15
11
55
2.02
1.28
1.4
1.2
10.33
7.86
u/ml
—
6
22
24
154
1.58
1.28
1.6
1.1
0.96
2.10
u/ml
—
5
9
368
3441
1.20
1.27
50.2
24.9
14.51
13.93
%
8.20
363
3405
9
44
2.06
1.27
1.1
1.4
—
—
—
0
0
8
35
2.30
1.27
2.3
2.0
101.50
93.93
ng/l
—
8
35
22
139
1.61
1.25
1.8
1.5
26457.41
13575.54
e6/l
0.70
17
99
17
100
1.72
1.24
2.1
1.9
2.06
4.95
iu/l
—
7
34
9
45
2.02
1.23
1.2
1.7
—
—
—
0
0
24
156
1.56
1.22
1.3
1.6
—
—
—
0
0
6
26
2.32
1.19
1.0
1.0
—
—
—
0
0
28
191
1.49
1.16
1.7
1.9
—
—
—
0
0
21
135
1.58
1.13
2.0
1.5
—
—
—
0
0
7
30
2.35
1.12
1.0
1.6
—
—
—
0
0
7
30
2.35
1.12
1.0
1.6
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
21
2.39
1.09
1.0
1.1
—
—
—
0
0
16
97
1.67
1.07
1.8
1.6
—
—
—
0
0
21
137
1.55
1.07
1.5
1.5
1.42
0.12
iu/ml
—
6
29
7
33
2.14
1.06
1.1
1.1
—
—
—
0
0
12
67
1.81
1.05
1.5
1.2
—
—
—
0
0
5
22
2.28
1.03
1.0
1.1
—
—
—
0
0
11
60
1.85
1.03
1.1
1.5
—
—
—
0
0
7
34
2.07
1.03
1.1
1.3
—
—
—
0
0
72
586
1.26
1.03
5.8
5.3
32.76
32.33
%
0.12
46
383
28
197
1.44
1.02
1.1
1.1
260.67
135.05
u/ml
—
9
72
11
61
1.82
0.99
1.1
1.5
—
—
—
0
0
10
54
1.87
0.97
5.1
3.4
13.40
11.89
index
—
10
36
9
50
1.81
0.97
1.0
1.8
—
—
—
0
0
6
116
0.51
0.95
3.0
1.7
10.62
4.38
mg/l
—
6
90
11
62
1.79
0.94
1.1
1.5
—
—
—
0
0
15
93
1.63
0.94
1.7
1.7
—
—
—
0
0
25
175
1.45
0.94
1.8
1.8
—
—
—
0
0
7
37
1.90
0.94
1.0
1.4
—
—
—
0
0
7
37
1.90
0.94
1.0
1.4
—
—
—
0
0
9
52
1.74
0.92
1.0
1.7
—
—
—
0
0
13
78
1.68
0.92
2.0
1.8
—
—
—
0
0
6
30
2.01
0.87
3.8
2.4
26.50
33.18
mg/l
—
6
22
8
48
1.68
0.79
1.5
1.2
—
—
—
0
0
138
1239
1.15
0.72
3.1
3.4
0.69
0.83
ug/l
1.44
101
851
5
28
1.79
0.66
3.8
4.2
0.60
0.71
%
—
5
28
12
78
1.55
0.66
1.7
1.3
13926.57
102338.76
e6/l
—
7
46
10
62
1.62
0.65
1.1
1.5
—
—
—
0
0
13
188
0.68
0.63
1.6
1.8
3.03
3.39
mmol/l
—
8
138
0
21
0.00
0.60
0.0
1.0
—
1.13
—
0
15
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.6
—
—
—
0
0
0
21
0.00
0.60
0.0
1.6
—
—
—
0
0
8
52
1.55
0.59
1.1
1.4
—
—
—
0
0
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
6
36
1.67
0.57
1.0
1.1
—
—
—
0
0
8
55
1.46
0.56
2.5
1.6
—
—
—
0
0
6
37
1.63
0.55
1.2
1.8
—
—
—
0
0
12
82
1.47
0.54
7.5
5.6
12.30
12.52
mg/l
0.06
12
77
10
66
1.52
0.53
1.6
1.4
—
—
—
0
0
9
63
1.44
0.52
1.4
3.1
—
22.55
—
0
29
9
64
1.41
0.51
7.0
4.2
—
—
—
0
0
56
483
1.18
0.51
1.7
1.4
—
—
—
0
0
30
362
0.82
0.45
1.4
1.4
—
—
—
0
0
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
12
87
1.39
0.42
2.2
1.9
32.92
32.76
pg
0.05
12
87
5
32
1.57
0.42
2.4
2.3
—
—
—
0
0
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
5
35
1.43
0.39
1.4
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
9.63
—
0
19
0
19
0.00
0.39
0.0
1.1
—
14.61
—
0
7
6
42
1.43
0.35
1.3
1.2
9.95
7.31
mmol/l
—
6
36
9
72
1.25
0.25
1.1
1.4
—
313.91
—
0
32
44
399
1.11
0.24
2.4
2.5
12.96
12.73
nmol/l
0.06
38
346
5
38
1.32
0.23
1.0
1.1
—
65.00
—
0
6
5
38
1.32
0.23
1.4
1.6
—
—
—
0
0
5
40
1.25
0.22
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.7
—
2.82
—
0
5
5
43
1.16
0.21
1.4
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
165
1709
0.95
0.19
2.1
2.0
1.40
1.29
mmol/l
1.05
137
1388
7
58
1.21
0.18
2.1
2.9
—
—
—
0
0
8
71
1.13
0.16
2.8
3.1
13.50
32.85
u/ml
—
8
71
19
169
1.13
0.14
1.2
1.0
—
—
—
0
0
9
83
1.09
0.14
1.1
1.2
—
—
—
0
0
5
47
1.06
0.09
1.2
1.1
—
2.28
—
0
6
7
65
1.08
0.08
1.6
1.5
—
—
—
0
0
9
84
1.07
0.07
1.4
1.1
—
2.47
—
0
6
9
85
1.06
0.07
1.4
1.3
—
—
—
0
0
8
94
0.85
0.06
9.6
2.8
17.09
10.75
pmol/l
—
8
94
12
129
0.93
0.03
5.6
4.3
31.43
31.09
mg/l
0.01
12
97
17
162
1.05
0.02
5.3
3.1
31.01
74.77
u/ml
1.08
17
157
10
103
0.97
0.00
1.4
1.2
468.50
516.36
mg/l
—
10
98
11
113
0.97
0.00
1.2
1.4
—
—
—
0
0
22
224
0.98
0.00
1.3
1.3
—
48.44
—
0
20
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.17
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
25.52
—
0
6
0
6
0.00
-0.00
0.0
2.3
—
38.50
—
0
6
6
59
1.02
-0.00
1.2
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.9
—
85.67
—
0
7
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint HYPOTE_DRUGS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| HYPOTE_DRUGS | 2.009 [1.68, 2.4] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.442 |
During the follow-up period (1.1.1998 — 31.12.2019), 1003 out of 1827 females with HYPOTE_DRUGS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| HYPOTE_DRUGS | 2.434 [1.91, 3.11] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 948 out of 1685 males with HYPOTE_DRUGS died.
Mortality risk
Mortality risk for people of age
years, who have HYPOTE_DRUGS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.193% | 0.515% |
| 5 | 1.172% | 2.872% |
| 10 | 2.94% | 6.92% |
| 15 | 5.423% | 12.823% |
| 20 | 9.768% | 21.299% |
Relationships between endpoints
↥Index endpoint: HYPOTE_DRUGS – Hypotension due to drugs
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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