info icon

Malignant neoplasm of other and unspecified male genital organs, including Hilmo

C3_MALE_GENITAL_NAS_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only males

244368

2. Check conditions

None

244368

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C63
  • Hospital discharge: ICD-9 187
  • Hospital discharge: ICD-8 187
  • Cause of death: ICD-10 C63
  • Cause of death: ICD-9 187
  • Cause of death: ICD-8 187
  • Cause of death: excluded ICD-9 187[1-4]
  • Cause of death: excluded ICD-8 1870
  • Cancer registry: Topography ICD-O-3 C63
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

72

4. Check minimum number of events

None

72

5. Include endpoints

None

72

6. Filter based on genotype QC (FinnGen only)

66

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 66 - 66
Unadjusted period prevalence (%) 0.03 - 0.03
Median age at first event (years) 66.19 - 66.19

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
68
Matched controls
680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
20.9
19
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
19.7
18
*
KFC00
NOMESCO Finland
Unilateral orchiectomy
129.2
18.6
19
*
130
Kela drug reimbursment
Malignant tumour
+∞
17.4
16
*
116
Kela drug reimbursment
Prostate cancer
+∞
12.9
12
*
C63.2
ICD-10 Finland
Malignant neoplasm: Scrotum
+∞
10.7
10
*
H02AB02
ATC
dexamethasone; systemic
64.5
10.0
11
*
C63.9
ICD-10 Finland
Malignant neoplasm: Male genital organ, unspecified
+∞
9.6
9
*
C63.0
ICD-10 Finland
Malignant neoplasm: Epididymis
+∞
9.6
9
*
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
9.6
9
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
17.2
9.2
14
10
N02AA05
ATC
oxycodone; systemic
5.6
9.0
21
50
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
102.2
8.6
9
*
L02BB03
ATC
bicalutamide; oral
+∞
8.5
8
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
+∞
8.5
8
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
+∞
8.5
8
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.7
8.3
26
79
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
76.8
6.5
7
*
A04AA01
ATC
ondansetron; systemic, rectal
20.4
6.5
9
5
Z51.5
ICD-10 Finland
Palliative care
10.1
6.4
12
14
WF002
NOMESCO Finland
Radical radiotherapy
+∞
6.3
6
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
6.3
6
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
6.3
6
*
JN4BD
NOMESCO Finland
Extensive body CT
11.7
6.3
11
11
UKC02
NOMESCO Finland
Cystoscopy
3.8
6.0
24
85

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
34
103
5.60
11.35
2.8
1.5
—
—
—
0
0
14
11
15.62
8.84
1.6
1.1
—
—
—
0
0
18
30
7.76
7.75
1.3
1.0
—
—
—
0
0
34
147
3.63
6.38
3.7
2.4
—
—
—
0
0
29
129
3.18
4.98
5.2
2.7
—
—
—
0
0
36
190
2.90
4.46
4.8
3.0
—
—
estimate
—
0
0
19
70
3.38
4.36
2.2
1.9
—
—
—
0
0
11
21
6.03
4.36
3.2
1.6
—
—
—
0
0
29
142
2.82
4.06
8.9
4.4
—
—
—
0
0
16
57
3.36
3.84
20.1
13.7
—
—
—
0
0
12
32
4.33
3.61
24.1
25.5
15.26
15.53
%
0.12
12
32
21
92
2.86
3.55
2.2
2.1
—
—
—
0
0
39
234
2.56
3.52
17.6
9.5
1.18
1.20
mmol/l
0.47
39
213
23
107
2.74
3.47
2.7
1.6
28.74
29.21
s
0.23
23
102
43
282
2.43
3.05
29.4
18.8
1.48
1.40
inr
0.34
36
239
27
146
2.41
2.94
5.9
2.7
0.89
0.33
e6/l
0.30
20
104
15
61
2.87
2.86
21.3
20.6
115.27
121.44
g/l
0.58
15
61
30
172
2.33
2.85
9.0
4.6
—
—
—
0
0
30
172
2.33
2.85
10.4
4.5
—
—
—
0
0
30
172
2.33
2.85
6.2
2.8
180.14
88.56
e6/l
0.24
23
131
7
14
5.44
2.80
1.0
1.1
—
—
—
0
0
39
255
2.24
2.66
12.6
3.9
12.63
14.30
umol/l
0.44
39
243
18
84
2.55
2.64
3.2
3.0
2.15
2.13
g/l
0.07
18
76
17
78
2.57
2.57
19.4
16.9
7.42
7.41
ph
—
8
45
17
81
2.47
2.37
3.4
3.1
21.54
23.62
%
0.46
17
75
11
41
3.00
2.34
1.5
1.4
58.70
66.00
g/l
1.34
11
33
25
144
2.16
2.26
13.8
3.9
7.38
7.39
ph
0.60
16
102
41
286
2.09
2.24
16.5
5.4
4.52
4.54
e9/l
0.02
35
244
30
187
2.08
2.21
7.7
3.2
1361.44
79.57
e6/l
0.56
23
133
38
263
2.01
2.07
8.6
4.8
0.63
0.62
e9/l
0.02
30
221
38
263
2.01
2.07
8.6
4.8
0.04
0.04
e9/l
0.09
29
222
18
94
2.24
2.04
3.6
2.9
11.39
13.00
umol/l
0.73
18
85
8
27
3.22
2.01
2.4
2.4
—
—
—
0
0
38
266
1.97
1.97
9.2
5.0
2.40
1.77
e9/l
0.41
31
230
17
88
2.24
1.96
19.2
9.8
103.06
104.18
mmol/l
0.38
17
88
49
377
2.07
1.92
13.9
5.6
82.53
79.37
u/l
0.19
49
350
12
54
2.48
1.86
1.2
1.4
—
—
—
0
0
38
271
1.91
1.82
10.4
4.9
0.18
0.21
e9/l
0.67
30
228
15
77
2.22
1.76
2.6
1.8
1.73
1.51
%
0.71
15
61
9
177
0.43
1.73
3.3
3.9
—
—
—
0
0
43
329
1.84
1.57
12.2
7.0
6.89
6.81
mmol/l
0.08
43
317
32
225
1.80
1.53
17.1
10.2
0.00
0.00
e9/l
-0.00
23
181
29
200
1.78
1.47
4.3
2.9
250.73
166.66
ug/l
0.39
29
182
36
266
1.75
1.43
5.2
3.1
265.00
0.00
estimate
—
6
53
10
47
2.32
1.42
1.5
1.4
—
—
—
0
0
6
23
2.76
1.40
1.0
1.1
—
—
—
0
0
12
62
2.14
1.38
1.7
1.8
—
—
—
0
0
22
143
1.80
1.34
3.1
1.9
2.90
2.64
mg/l
0.40
22
118
12
63
2.10
1.32
3.0
1.9
67.66
56.98
e9/l
—
7
49
5
18
2.91
1.31
2.4
1.5
22.80
20.44
s
—
5
18
48
391
1.77
1.30
45.6
19.2
14.22
13.73
%
1.41
48
386
29
206
1.71
1.30
5.4
3.0
6.29
6.14
ph
0.32
12
110
11
57
2.11
1.25
1.4
1.9
—
—
—
0
0
18
113
1.81
1.21
1.1
1.2
—
—
—
0
0
5
20
2.61
1.17
1.2
1.2
30.18
36.84
mg/l
—
5
20
5
20
2.61
1.17
1.2
1.2
30.16
47.91
mg/l
—
5
20
45
366
1.68
1.17
5.6
4.4
—
—
—
0
0
19
123
1.76
1.16
6.5
4.0
43.11
399.23
ng/l
1.02
19
105
8
41
2.08
1.13
4.6
16.3
—
—
—
0
0
7
33
2.25
1.09
1.0
1.5
—
—
—
0
0
9
47
2.05
1.07
1.6
1.6
—
—
—
0
0
7
37
1.99
0.97
5.3
5.4
89.70
116.56
ng/l
—
7
28
6
27
2.34
0.96
1.5
1.2
—
—
—
0
0
11
64
1.86
0.92
3.7
3.5
17.14
8.57
ug/l
0.31
11
55
12
74
1.75
0.85
4.2
3.5
5.87
5.89
kpa
0.03
12
69
8
47
1.79
0.84
1.0
1.4
—
—
—
0
0
6
32
1.96
0.84
1.2
1.4
—
—
—
0
0
12
75
1.73
0.81
4.1
3.4
-0.77
1.60
mmol/l
0.59
12
60
6
37
1.68
0.57
1.5
1.8
—
0.00
estimate
—
0
8
7
47
1.54
0.49
2.3
2.6
160.71
160.32
ug/g
—
7
40
55
511
1.40
0.44
46.3
21.6
139.75
139.64
mmol/l
0.06
55
503
55
511
1.40
0.44
47.0
21.6
4.02
4.05
mmol/l
0.39
55
502
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
5
35
1.46
0.40
1.0
2.5
0.94
1.20
%
—
5
35
5
35
1.46
0.40
1.0
2.5
0.76
0.55
%
—
5
35
25
211
1.29
0.39
3.2
2.7
1.18
0.84
ug/l
0.22
20
141
56
528
1.34
0.34
53.0
23.6
91.38
91.62
fl
0.15
56
522
56
529
1.33
0.32
53.1
23.7
7.53
6.98
e9/l
0.72
56
519
56
529
1.33
0.32
53.4
23.6
229.64
229.57
e9/l
0.00
56
519
56
529
1.33
0.32
53.4
23.8
127.57
139.05
g/l
3.87
56
524
56
529
1.33
0.32
53.0
23.5
30.15
30.65
pg
1.15
56
523
56
529
1.33
0.32
57.9
24.6
38.47
41.27
%
3.20
56
523
53
498
1.29
0.31
29.3
14.3
—
—
—
0
0
7
56
1.28
0.30
1.6
1.2
—
—
—
0
0
23
260
0.83
0.25
4.5
4.2
37.78
62.14
ng/l
0.77
18
207
29
260
1.20
0.25
2.5
2.1
86.66
91.30
pmol/l
0.22
17
149
23
202
1.21
0.24
2.9
4.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
6
48
1.27
0.21
2.8
3.1
7.34
7.36
ph
—
6
32
7
57
1.25
0.19
1.3
1.3
—
317.65
—
0
17
14
122
1.19
0.15
7.4
3.4
1.02
1.02
kg/l
—
9
74
9
108
0.81
0.14
2.7
2.0
1151.24
1269.85
nmol/l
—
9
85
47
489
0.87
0.14
6.3
6.4
2.31
2.44
mmol/l
0.62
47
451
10
86
1.19
0.11
2.2
4.0
—
—
—
0
0
49
474
1.12
0.10
6.2
7.6
40.22
40.90
mmol/mol
0.26
49
438
47
479
0.94
0.03
5.4
5.4
6.03
6.16
mmol/l
0.51
47
428
0
6
0.00
-0.00
0.0
3.3
—
375.67
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
34.17
—
0
6
0
8
0.00
-0.00
0.0
1.6
—
105.38
—
0
8
0
8
0.00
-0.00
0.0
1.6
—
1.19
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
142.09
—
0
7
0
7
0.00
-0.00
0.0
2.3
—
0.71
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
8.10
—
0
6
0
8
0.00
-0.00
0.0
1.6
—
4.16
—
0
8
0
6
0.00
-0.00
0.0
1.7
—
2.03
—
0
6
0
7
0.00
-0.00
0.0
2.1
—
15.44
—
0
7
0
8
0.00
-0.00
0.0
4.5
—
12.98
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
84.60
—
0
5
0
5
0.00
-0.00
0.0
4.4
—
0.30
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
59.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_MALE_GENITAL_NAS_WIDE – Malignant neoplasm of other and unspecified male genital organs, including Hilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).