Mixed specific developmental disorders

F5_MIXEDDEV

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F83
  • Cause of death: ICD-10 F83

2 out of 7 registries used, show all original rules.

979

4. Check minimum number of events

None

979

5. Include endpoints

None

979

6. Filter based on genotype QC (FinnGen only)

829

Control definitions (FinnGen only)

Control exclude
F5_PSYCHDEV

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F80-F89
Name in latin
Perturbationes progressus specificae mixtae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 32334 9898 22428
Only index persons 24048 7389 16659
Unadjusted period prevalence (%)
Whole population 0.52 0.28 0.63
Only index persons 0.52 0.27 0.64
Median age at first event (years)
Whole population 5.94 6.11 5.86
Only index persons 6.45 6.68 6.35

-FinnGen-

Key figures

All Female Male
Number of individuals 829 360 469
Unadjusted period prevalence (%) 0.18 0.13 0.22
Median age at first event (years) 6.68 7.47 6.08

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
913
Matched controls
8431
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
180.2
307.7
174
11
F83
ICD-10 Finland
Mixed specific developmental disorders
+∞
307.7
913
*
R62.0
ICD-10 Finland
Delayed milestone
25.9
281.8
220
102
XA800
NOMESCO Finland
Neuropsychological investigation
18.4
275.3
257
176
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
19.6
194.4
168
96
F82
ICD-10 Finland
Specific developmental disorder of motor function
302.5
159.4
162
6
Z2445
NOMESCO Finland
Psychologist
8.1
156.8
260
393
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.8
128.2
251
447
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
282.0
127.8
131
5
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
19.9
124.4
104
54
P85
ICPC
Mental retardation
21.4
116.3
94
45
N05AX08
ATC
risperidone; systemic
8.2
115.0
177
241
F80.1
ICD-10 Finland
Expressive language disorder
242.6
111.0
115
5
F80.2
ICD-10 Finland
Receptive language disorder
276.4
103.0
106
*
F80.9
ICD-10 Finland
Developmental disorder of speech and language, unspecified
216.4
99.6
104
5
N03AG01
ATC
valproic acid; systemic, rectal
7.3
94.2
157
232
F81.9
ICD-10 Finland
Developmental disorder of scholastic skills, unspecified
42.3
93.1
60
14
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.6
92.0
294
789
Z2446
NOMESCO Finland
Social worker
4.7
87.7
258
646
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
6.4
85.5
162
273
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
5.2
84.3
214
473
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
6.8
83.3
148
233
RL140, ,
NOMESCO Finland
25.1
81.0
61
24
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
175.1
81.0
86
5
R4120
NOMESCO Finland
Occupational therapy
6.9
80.7
141
218
F84.5
ICD-10 Finland
Asperger syndrome
34.6
78.1
53
15
Z31.5
ICD-10 Finland
Genetic counselling
5.5
76.6
174
347
Z50.5
ICD-10 Finland
Speech therapy
7.8
75.5
116
155
RL130, ,
NOMESCO Finland
24.3
75.0
57
23
Z3226
NOMESCO Finland
Physiotherapist
3.9
73.8
302
954
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
6.1
71.5
140
242
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
6.2
69.6
135
231
RT150, ,
NOMESCO Finland
17.8
66.9
58
32
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
172.1
64.9
69
*
R1260
NOMESCO Finland
Evaluation of communicative skills
16.1
64.8
59
36
183
Kela drug reimbursment
Lamotrigin and topiramate
13.5
62.8
63
46
F90.0
ICD-10 Finland
Disturbance of activity and attention
3.8
61.7
238
712
N05AX12
ATC
aripiprazole; systemic
5.3
61.1
140
279
N05BA09
ATC
clobazam; oral
10.7
60.8
71
66
G40.9
ICD-10 Finland
Epilepsy, unspecified
8.1
60.3
88
110
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
33.0
59.6
41
12
EBA15
NOMESCO Finland
Extraction of multiple teeth
8.2
57.7
83
102
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.3
55.0
284
1018
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.6
54.6
114
208
N06BA04
ATC
methylphenidate; oral
3.7
53.0
207
619
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.3
52.9
266
935
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
8.4
52.4
73
86
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.4
51.1
147
352
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
10.9
50.8
58
52
R4130
NOMESCO Finland
Speech therapy
7.5
50.5
78
104
F84.8
ICD-10 Finland
Other pervasive developmental disorders
496.2
50.4
51
*
IGV01
NOMESCO Finland
Psychiatric network contact
6.6
49.7
87
133
F84.0
ICD-10 Finland
Childhood autism
+∞
49.0
48
*
N03AX09
ATC
lamotrigine; oral
5.1
49.0
114
229
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.6
48.8
198
605
F80.8
ICD-10 Finland
Other developmental disorders of speech and language
105.9
48.7
54
5
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
5.1
47.6
112
227
N05BA01
ATC
diazepam; systemic, rectal
4.6
47.4
127
287
N05AH03
ATC
olanzapine; systemic
4.3
46.4
138
338
R1250
NOMESCO Finland
Evaluation of functional capability
12.6
46.2
48
37
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
233.6
46.0
48
*
N03AX14
ATC
levetiracetam; systemic
7.2
45.7
73
101
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
13.1
45.4
46
34
N03AF02
ATC
oxcarbazepine; oral
5.9
45.1
88
150
N05CD08
ATC
midazolam; nasal, systemic
6.6
44.5
77
116
A28
ICPC
Limited function/disability NOS
4.8
44.5
112
240
Z01.8
ICD-10 Finland
Other specified special examinations
3.1
44.2
237
856
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.9
43.7
274
1079
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.8
43.4
154
428
P24
ICPC
Specific learning problem
5.3
43.0
94
178
RT160, ,
NOMESCO Finland
12.1
41.5
44
35
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
5.3
41.4
91
173
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
18.6
41.4
35
18
R5599
NOMESCO Finland
Other rehabilitation service
7.1
41.4
66
91
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
10.1
40.9
49
47
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.6
40.6
155
452
H50.31
ICD-10 Finland
Intermittent exotropia
6.7
35.5
60
88
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.3
34.6
99
234
Z3231
NOMESCO Finland
Registered nurse
2.4
34.5
364
1817
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.6
33.7
128
370
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
33.6
295
1352
DFF20
NOMESCO Finland
Audiometry for children
7.4
33.3
51
67
Z2221
NOMESCO Finland
Medical doctor
2.5
32.8
274
1225
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
10.1
32.7
39
37
Z3229
NOMESCO Finland
Other healthcare associate professional
3.4
32.5
130
388
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
4.1
32.1
98
243
RS222, ,
NOMESCO Finland
8.6
32.1
43
48
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
3.5
31.9
125
368
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
31.1
342
1723
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
3.3
30.5
127
388
OAB43, ,
SPAT
0.3
30.1
111
2562
N03AX11
ATC
topiramate; oral
5.7
29.9
59
101
N05AH04
ATC
quetiapine; oral
2.6
29.9
228
970
ZY010
NOMESCO Finland
Hospital outpatient
3.1
29.9
140
460
K03.66
ICD-10 Finland
Tooth plaque
2.6
29.5
208
851
R4110
NOMESCO Finland
Physiotherapy
2.4
29.1
266
1229
N05AH02
ATC
clozapine; systemic
6.5
28.9
50
75
N03AX18
ATC
lacosamide; systemic
11.8
28.9
31
25
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
9.6
28.3
35
35
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
27.7
128
416
P22
ICPC
Child behaviour symptom/complaint
3.6
27.7
101
283
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.1
27.4
128
419
F79.1
ICD-10 Finland
Unspecified mental retardation, significant impairment of behaviour requiring attention or treatment
52.6
27.3
33
6
R5140
NOMESCO Finland
Monitoring the use of the aid
5.1
27.2
60
114
WYA50
NOMESCO Finland
Student oral health check consistent with decree to assess need for oral health guidance and services
0.2
26.4
45
1640
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
59.2
26.1
31
5
RT490, ,
NOMESCO Finland
26.6
25.8
36
13
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.5
25.8
98
282
F88
ICD-10 Finland
Other disorders of psychological development
35.1
25.3
33
9
H01AC01
ATC
somatropin; parenteral
4.7
25.3
62
129
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
4.1
25.3
73
173
XX4AW, ,
NOMESCO Finland
6.1
25.2
46
73
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.3
25.1
106
326
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.2
25.1
72
170
N05AA02
ATC
levomepromazine; systemic
5.8
25.0
48
80
F20.9
ICD-10 Finland
Schizophrenia, unspecified
7.3
24.7
38
50
ZXE00
NOMESCO Finland
One hour or less
2.1
23.9
373
2111
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.6
23.8
84
230
ICB06, ,
NOMESCO Finland
5.2
23.6
51
95
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.2
23.3
101
315
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
3.4
23.2
89
257
IGY02
NOMESCO Finland
Psychiatric monitoring contact
2.9
23.1
123
432
F70
ICD-10 Finland
Mild mental retardation
227.3
23.0
24
*
IEV99
NOMESCO Finland
Other psychiatric network intervention
5.0
23.0
52
101
SPAT1229
SPAT
Assessment of need for aid
6.1
22.8
41
64
L28
ICPC
Limited function/disability (L)
3.1
22.6
102
326
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
4.9
22.5
52
103
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.2
22.4
95
292
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
5.6
22.4
44
75
F89
ICD-10 Finland
Unspecified disorder of psychological development
34.5
22.2
29
8
P99
ICPC
Psychological disorders other
3.9
21.6
67
167
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
4.5
21.6
56
122
SPAT1297
SPAT
Other function in accordance with speech therapy nomenclature
5.8
21.0
40
66
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
21.0
275
1444
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
6.6
20.8
35
51
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
25.1
20.6
29
11
OAA43, ,
SPAT
2.8
20.3
112
400
T82
ICPC
Obesity
4.2
20.3
56
128
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
20.3
143
578
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.4
20.1
53
117
ZYC01
NOMESCO Finland
Remote contact by phone
3.0
20.1
97
322
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
18.5
20.0
31
16
H52.2
ICD-10 Finland
Astigmatism
3.7
19.9
66
173
C03CA01
ATC
furosemide; systemic
3.7
19.8
65
169
Z02.7
ICD-10 Finland
Issue of medical certificate
3.0
19.8
94
309
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.3
19.8
79
234
N06AB04
ATC
citalopram; systemic
3.0
19.6
95
316
RS220, ,
NOMESCO Finland
5.5
19.4
39
68
SPAT1389
SPAT
Visit based on need for special support
2.4
19.2
146
611
H81
ICPC
Excessive ear wax
2.8
19.1
107
385
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
3.7
19.1
64
169
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
4.4
19.0
50
110
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
7.6
19.0
28
35
H50.0
ICD-10 Finland
Convergent concomitant strabismus
4.9
18.9
43
84
IGP01
NOMESCO Finland
Psychiatric family contact
3.4
18.8
73
212
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.7
18.7
62
162
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.7
18.7
62
162
Q99.8
ICD-10 Finland
Other specified chromosome abnormalities
18.4
18.7
29
15
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.7
18.5
108
397
F71.1
ICD-10 Finland
Moderate mental retardation, significant impairment of behaviour requiring attention or treatment
52.0
18.3
22
*
SPAT1396
SPAT
Meeting with multidisciplinary group of experts
3.9
18.2
57
143
N05BA06
ATC
lorazepam; systemic, sublingual
6.0
18.2
33
52
N06BA09
ATC
atomoxetine; oral
6.0
18.2
33
52
F93.9
ICD-10 Finland
Childhood emotional disorder, unspecified
6.2
18.1
32
49
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
4.7
18.1
43
87
SPAT1234
SPAT
Support of social functional capacity
4.8
17.9
42
84
F92.9
ICD-10 Finland
Mixed disorder of conduct and emotions, unspecified
7.3
17.8
27
35
F98.8
ICD-10 Finland
Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
6.5
17.7
30
44
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.8
17.6
95
335
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
17.6
171
794
H52.0
ICD-10 Finland
Hypermetropia
3.4
17.5
67
193
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.4
17.5
142
611
N05AD01
ATC
haloperidol; systemic
7.5
17.4
26
33
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
4.3
17.1
46
103
IGY02, ,
SPAT
4.8
17.1
40
80
101
Kela drug reimbursment
Anterior pituitary hypofunction
4.8
17.1
40
80
A06AD11
ATC
lactulose; oral
3.1
17.0
75
236
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
6.4
16.9
29
43
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.6
16.8
58
156
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.2
16.8
69
208
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
2.9
16.8
83
279
IGY99
NOMESCO Finland
Other psychiatric treatment contact
2.8
16.7
88
306
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
5.9
16.7
31
50
XCK00
NOMESCO Finland
Perimetry
5.1
16.7
36
67
N03AX22
ATC
perampanel; oral
22.7
16.7
24
10
WX002
NOMESCO Finland
Sedation and analgesia
2.5
16.7
113
447
N29
ICPC
Neurological sympt/complt other
6.3
16.6
29
44
SPAT1395
SPAT
Health check-up of persons outside student and working life
6.5
16.5
28
41
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
16.4
181
881
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
5.8
16.4
31
51
G47.3
ICD-10 Finland
Sleep apnoea
2.6
16.3
100
376
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
3.6
16.2
55
146
H50.30
ICD-10 Finland
Intermittent esotropy
4.8
16.2
38
76
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
18.2
16.2
25
13
H53.0
ICD-10 Finland
Amblyopia ex anopsia
4.2
16.1
45
104
SCA02
NOMESCO Finland
Preventive oral health care
1.8
16.1
351
2153
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.9
16.0
49
121
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
16.0
291
1686
WZB00, ,
SPAT
0.3
15.8
60
1452
N88
ICPC
Epilepsy
7.0
15.8
25
34
WYA20
NOMESCO Finland
Home visit
7.0
15.8
25
34
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.8
15.8
303
1785
AA1AD
NOMESCO Finland
CT of head and brain
2.4
15.6
121
509
DFF00
NOMESCO Finland
Pure tone audiometry
3.2
15.3
65
200
UDC00
NOMESCO Finland
Ear microscopy
2.5
15.1
100
390
F81.0
ICD-10 Finland
Specific reading disorder
13.7
15.1
26
18
JDB10
NOMESCO Finland
Percutaneous gastrostomy
7.2
15.0
23
30
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.7
15.0
85
307
H50.1
ICD-10 Finland
Divergent concomitant strabismus
6.9
15.0
24
33
RT190, ,
NOMESCO Finland
16.2
15.0
24
14
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.0
14.9
71
233
K08.3
ICD-10 Finland
Retained dental root
4.0
14.9
44
106
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.8
14.8
46
115
602
Kela drug reimbursment
Children's severe malnutrition
3.4
14.7
55
156
F80.0
ICD-10 Finland
Specific speech articulation disorder
6.4
14.6
25
37
IBZ06
NOMESCO Finland
Evaluation concerning developmental neuropsychiatry
4.9
14.6
33
64
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
14.5
202
1066
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
3.6
14.5
49
130
EBA05
NOMESCO Finland
Complicated extraction of tooth
2.1
14.3
159
774
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
6.2
14.2
25
38
R32
ICD-10 Finland
Unspecified urinary incontinence
5.3
14.0
29
52
T90
ICPC
Diabetes non-insulin dependent
3.2
13.8
58
177
RT420, ,
NOMESCO Finland
14.5
13.8
23
15
IBB01
NOMESCO Finland
Psychiatric functioning capacity evaluation
11.8
13.7
25
20
U04
ICPC
Incontinence urine
4.7
13.7
32
64
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
39.9
13.6
17
*
F93.89
ICD-10 Finland
Other childhood emotional disorders
3.3
13.5
53
155
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
3.8
13.5
42
105
KAY40, ,
NOMESCO Finland
0.1
13.4
8
498
Z72.8
ICD-10 Finland
Other problems related to lifestyle
6.7
13.4
22
31
R62.9
ICD-10 Finland
Lack of expected normal physiological development, unspecified
28.2
13.4
18
6
RS314, ,
NOMESCO Finland
22.3
13.3
19
8
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
4.0
13.2
39
94
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.0
13.2
38
90
3159X
ICD-9 Finland
Specific delays in development, Unspecified delay in development
+∞
13.2
13
*
RS140, ,
NOMESCO Finland
10.8
13.1
25
22
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
13.1
222
1246
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
13.1
72
256
R4110, ,
SPAT
2.6
13.1
79
295
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
2.6
13.0
80
301
Q89.7
ICD-10 Finland
Multiple congenital malformations, not elsewhere classified
31.9
13.0
17
5
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
13.8
13.0
22
15
TLC00
NOMESCO Finland
Insertion of intrauterine device
3.2
12.9
52
155
RS211, ,
NOMESCO Finland
6.0
12.7
23
36
WX402
NOMESCO Finland
General anaesthesia
1.8
12.7
236
1361
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
4.3
12.7
34
76
Z04.4
ICD-10 Finland
Examination and observation following alleged rape and seduction
5.1
12.6
27
50
IEP03
NOMESCO Finland
Focused parental counselling
3.4
12.4
45
125
Q93.5
ICD-10 Finland
Other deletions of part of a chromosome
46.9
12.4
15
*
N03AG04
ATC
vigabatrin; oral
10.3
12.4
24
22
K05.18
ICD-10 Finland
Chronic gingivitis
2.3
12.4
104
452
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.7
12.3
68
242
P72
ICPC
Schizophrenia
5.0
12.3
27
51
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
12.2
160
823
SFA30
NOMESCO Finland
Three-surface restoration
1.8
12.2
223
1278
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
12.2
153
776
3153A
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[KIELENKEHITYKSEN ERITYISVAIKEUS]
+∞
12.1
12
*
RL720, ,
NOMESCO Finland
121.7
12.1
13
*
OAA68, ,
SPAT
4.9
12.1
27
52
TDA90, ,
SPAT
3.5
12.0
42
114
F91.9
ICD-10 Finland
Conduct disorder, unspecified
11.5
12.0
22
18
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
16.3
12.0
19
11
OAA62, ,
SPAT
0.3
12.0
28
884
FM2CE, ,
NOMESCO Finland
2.5
11.9
76
291
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
11.9
169
893
F98.00
ICD-10 Finland
Nonorganic enuresis nocturna
3.4
11.8
43
120
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.6
11.8
70
259
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
3.0
11.8
55
179
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.1
11.7
126
604
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.9
11.6
58
196
N03AX15
ATC
zonisamide; oral
16.9
11.5
18
10
RS312, ,
NOMESCO Finland
16.9
11.5
18
10
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
2.6
11.5
70
262
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
11.5
89
373
U07.2
ICD-10 Finland
COVID-19, virus not identified
0.5
11.5
88
1605
SPAT1262
SPAT
Handing over of treatment supplies
2.4
11.4
83
338
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
2.2
11.3
98
431
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.4
11.3
42
119
H47.2
ICD-10 Finland
Optic atrophy
13.8
11.3
19
13
G40.10
ICD-10 Finland
Simple partial seizures
11.0
11.3
21
18
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.4
11.2
81
329
RS122, ,
NOMESCO Finland
15.4
11.2
18
11
3141A
ICD-9 Finland
Hyperkinetic syndrome of childhood, Hyperkinesis with developmental delay
+∞
11.1
11
*
3153X
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[PUHEEN KEHITYKSEN ERITYISVAIKEUS]
+∞
11.1
11
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.7
11.1
62
222
N06AB03
ATC
fluoxetine; oral
2.2
11.1
98
434
P07.2
ICD-10 Finland
Extreme immaturity
21.5
11.1
16
7
E66.01
ICD-10 Finland
Obesity due to excess calories
2.3
11.1
90
385
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
5.0
11.0
24
45
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
5.0
11.0
24
45
SPAT1216
SPAT
Assessment of functional ability
2.4
11.0
79
320
181
Kela drug reimbursment
Retigabine and vigabatrin
10.4
11.0
21
19
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
11.0
134
672
WZC30, ,
SPAT
2.7
10.9
58
203
DFF10
NOMESCO Finland
Measurement of acoustic impedance (tympanometry and reflex testing)
5.9
10.8
20
32
EB1VA, ,
NOMESCO Finland
2.0
10.6
130
652
N03AX23
ATC
brivaracetam; systemic
11.9
10.6
19
15
R5110, ,
SPAT
3.8
10.5
32
79
G40.89
ICD-10 Finland
Other epilepsy
10.5
10.5
20
18
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.1
10.5
114
548
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
3.9
10.5
31
75
KAY60, ,
NOMESCO Finland
0.0
10.4
*
269
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.9
10.4
23
44
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
5.3
10.3
21
37
M41.4
ICD-10 Finland
Neuromuscular scoliosis
11.2
10.3
19
16
F80
ICD-10 Finland
Specific developmental disorders of speech and language
56.1
10.3
12
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
10.3
174
970
K59.09
ICD-10 Finland
Constipation, unspecified
2.5
10.3
66
254
RF120, ,
NOMESCO Finland
9.0
10.2
21
22
XKD00
NOMESCO Finland
Uroflowmetry
2.7
10.2
55
194
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
12.1
10.2
18
14
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.6
10.1
391
2705
SPAT1240
SPAT
Therapeutic discussion
1.9
10.1
145
767
Q87.06
ICD-10 Finland
Velocardiofacial syndrome
102.7
10.1
11
*
ZXY82
NOMESCO Finland
Nurse in multidisciplinary team
4.8
10.1
23
45
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
5.2
10.0
21
38
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
10.5
10.0
19
17
SCA03
NOMESCO Finland
Preventive oral health care, extensive
2.0
10.0
110
530
P29
ICPC
Psychological sympt/compl other
1.9
10.0
152
819
ZXA00
NOMESCO Finland
Right side
2.0
10.0
112
544
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.2
10.0
88
390
Z29
ICPC
Social problem NOS
3.0
9.9
44
139
ZXE21
NOMESCO Finland
Procedure duration at least 3 but less than 4 hours
4.9
9.9
22
42
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
17.6
9.8
15
8
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
9.8
448
3216
N03AF01
ATC
carbamazepine; oral, rectal
5.1
9.8
21
39
F40.2
ICD-10 Finland
Specific (isolated) phobias
4.2
9.8
26
58
R4120, ,
SPAT
7.7
9.7
22
27
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.6
9.7
33
88
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
9.7
97
451
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.8
9.7
159
877
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
5.2
9.6
20
36
XF404
NOMESCO Finland
Ambulatory ECG
2.6
9.6
57
211
R11
ICD-10 Finland
Nausea and vomiting
2.0
9.6
120
606
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
4.0
9.6
27
63
N03AD01
ATC
ethosuximide; oral
13.6
9.6
16
11
Z29.8
ICD-10 Finland
Other specified prophylactic measures
2.5
9.5
62
240
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
4.9
9.5
21
40
TJD20
NOMESCO Finland
Change of gastrostomy tube
5.4
9.5
19
33
RT130, ,
NOMESCO Finland
15.6
9.4
15
9
N03AF03
ATC
rufinamide; oral
18.7
9.4
14
7
G91.1
ICD-10 Finland
Obstructive hydrocephalus
11.4
9.4
17
14
F90.1
ICD-10 Finland
Hyperkinetic conduct disorder
11.4
9.4
17
14
D12
ICPC
Constipation
3.2
9.4
37
109
SPAT1139
SPAT
Nutrition survey
3.7
9.3
30
77
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.7
9.3
30
77
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.9
9.3
44
144
ZXD20
NOMESCO Finland
Day surgery
2.1
9.3
88
400
T16
ICD-10 Finland
Foreign body in ear
4.4
9.3
24
52
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
5.1
9.3
20
37
UKC02
NOMESCO Finland
Cystoscopy
2.8
9.3
48
165
F92.8
ICD-10 Finland
Other mixed disorders of conduct and emotions
7.6
9.3
21
26
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
9.3
57
215
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.8
9.2
21
41
EJC20
NOMESCO Finland
Operation on frenulum of tongue
3.8
9.2
28
69
F98.9
ICD-10 Finland
Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
5.2
9.2
19
34
201
Kela drug reimbursment
Chronic cardiac insufficiency
4.4
9.1
23
49
N05AF03
ATC
chlorprothixene; systemic
4.4
9.1
23
49
301
Kela drug reimbursment
Growth hormone
4.3
9.1
24
53
RL710, ,
NOMESCO Finland
+∞
9.1
9
*
N03AE01
ATC
clonazepam; systemic
3.5
9.1
31
83
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
9.0
532
4008
N07BB01
ATC
disulfiram; oral
3.6
8.8
29
76
ZXD05
NOMESCO Finland
Urgent procedure
1.7
8.8
202
1224
WX003
NOMESCO Finland
Sedation or analgesia orally, rectally or intramuscularly without general anesthesia
3.2
8.8
35
104
H13
ICPC
Plugged feeling ear
1.9
8.7
116
597
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
14.6
8.6
14
9
SPAT1281
SPAT
Other administrative function
2.0
8.6
91
432
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
10.7
8.6
16
14
ZXA05
NOMESCO Finland
Left side
2.0
8.6
105
525
A41.9
ICD-10 Finland
Sepsis, unspecified
3.1
8.6
36
110
IHZ04, ,
SPAT
3.1
8.6
37
115
Q93.8
ICD-10 Finland
Other deletions from the autosomes
22.4
8.6
12
5
F99
ICD-10 Finland
Mental disorder, not otherwise specified
3.2
8.5
34
101
OAB95, ,
SPAT
0.3
8.5
17
591
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
8.5
99
488
KAY20, ,
NOMESCO Finland
0.1
8.5
*
291
ZYC02, ,
SPAT
0.3
8.4
22
658
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.6
8.4
51
191
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.6
8.4
49
180
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
4.8
8.4
19
37
UJD02
NOMESCO Finland
Gastroscopy
3.6
8.4
28
74
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.5
8.4
52
197
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
8.4
155
884
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
10.0
8.4
16
15
W0A12
NOMESCO Finland
Planned therapy visit for psychiatric disease
8.1
8.3
18
21
A10BA02
ATC
metformin; oral
2.3
8.3
67
286
EBA30
NOMESCO Finland
Extraction of root of tooth
4.1
8.3
23
53
ZXY80
NOMESCO Finland
Doctor in multidisciplinary team
4.4
8.3
21
45
R33
ICD-10 Finland
Retention of urine
4.2
8.3
22
49
R13
ICD-10 Finland
Dysphagia
3.0
8.2
36
113
SPAT1097
SPAT
Recording of ECG
2.6
8.2
47
171
OAB48, ,
SPAT
0.5
8.2
60
1128
S18
ICPC
Laceration/cut
1.5
8.2
317
2169
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
2.3
8.2
66
282
N05BA04
ATC
oxazepam; oral
1.8
8.2
142
795
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
8.2
400
2877
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
7.1
8.2
19
25
A10BJ06
ATC
semaglutide; parenteral
4.7
8.1
19
38
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
4.0
8.1
23
54
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
7.7
8.1
18
22
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
4.5
8.1
20
42
F60.9
ICD-10 Finland
Personality disorder, unspecified
4.5
8.1
20
42
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.7
8.1
26
67
OAA67, ,
SPAT
0.4
8.1
43
915
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.2
8.0
67
290
EMB30
NOMESCO Finland
Adenotomy
1.7
8.0
155
894
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
3.7
8.0
25
63
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
11.9
8.0
14
11
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
11.9
8.0
14
11
IEY01
NOMESCO Finland
Psychoeducation, individual
3.8
8.0
24
59
SPAT1321
SPAT
Health examination of person liable for military service
0.5
7.9
73
1267
H02AB09
ATC
hydrocortisone; systemic
2.4
7.9
54
214
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.5
7.9
49
186
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.3
7.9
60
250
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
3.3
7.9
29
82
P98
ICPC
Psychosis NOS/other
6.3
7.9
20
30
WYA30, ,
SPAT
6.3
7.9
20
30
RS120, ,
NOMESCO Finland
8.0
7.9
17
20
K59.0
ICD-10 Finland
Constipation
2.4
7.8
55
221
Z03
ICPC
Housing/neighbourhood problem
13.5
7.8
13
9
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.5
7.8
27
73
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
2.7
7.8
42
148
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
7.8
97
488
WW200, ,
SPAT
1.7
7.8
175
1050
N06AX16
ATC
venlafaxine; oral
1.9
7.8
103
529
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
3.8
7.8
24
60
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
3.8
7.8
24
60
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.1
7.8
32
97
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
7.8
685
5539
199
Kela drug reimbursment
Rufinamide
16.0
7.7
12
7
S29
ICPC
Skin symptom/complaint other
1.6
7.7
189
1160
N92.2
ICD-10 Finland
Excessive menstruation at puberty
4.7
7.7
18
36
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
20.5
7.7
11
5
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
4.0
7.7
22
52
R4190
NOMESCO Finland
Nutritional therapy
1.8
7.7
115
615
A97
ICPC
No disease
1.6
7.7
251
1650
T83
ICPC
Overweight
3.4
7.7
27
74
R39.1
ICD-10 Finland
Other difficulties with micturition
4.5
7.7
19
40
G03DC03
ATC
lynestrenol; oral
4.1
7.7
21
48
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.5
7.6
49
189
SPAT1307
SPAT
Psychosocial counselling and guidance
1.7
7.6
136
767
Z01.2
ICD-10 Finland
Dental examination
1.5
7.6
581
4546
T74.1
ICD-10 Finland
Physical abuse
2.9
7.6
36
119
H61.2
ICD-10 Finland
Impacted cerumen
2.4
7.5
54
219
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.1
7.5
76
355
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.4
7.5
27
75
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
2.7
7.5
39
135
U05
ICPC
Urination problems other
3.3
7.5
28
80
Z06
ICPC
Unemployment problem
4.6
7.5
18
37
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.3
7.5
59
250
ZXY60
NOMESCO Finland
2-person team, nurses
4.3
7.5
19
41
N05AL05
ATC
amisulpride; oral
41.9
7.4
9
*
RT422, ,
NOMESCO Finland
41.9
7.4
9
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
2.8
7.4
36
120
SPAT1254
SPAT
Administration of medicine
1.6
7.4
191
1186
K02.1
ICD-10 Finland
Caries of dentine
1.5
7.4
596
4699
A11CC03
ATC
alfacalcidol; systemic
3.4
7.4
27
76
IEP01
NOMESCO Finland
Psychoeducation, family
3.7
7.4
23
58
IEV99, ,
SPAT
8.8
7.4
15
16
3046, ,
Kela drug reimbursment
14.0
7.4
12
8
N05BE01
ATC
buspirone; oral
3.5
7.4
25
67
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.5
7.3
47
181
H66.9
ICD-10 Finland
Otitis media, unspecified
1.6
7.3
219
1408
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
3.3
7.3
28
81
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.7
7.3
136
775
K04.1
ICD-10 Finland
Necrosis of pulp
2.0
7.3
78
373
N06BA12
ATC
lisdexamfetamine; oral
2.6
7.3
42
154
K07.24
ICD-10 Finland
Open bite
2.5
7.2
45
171
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.7
7.2
39
138
R27.0
ICD-10 Finland
Ataxia, unspecified
74.5
7.2
8
*
F22.0
ICD-10 Finland
Delusional disorder
8.3
7.1
15
17
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
6.3
7.1
18
27
N28
ICPC
Limited function/disability (N)
6.3
7.1
18
27
WX882
NOMESCO Finland
High dependency care
2.0
7.1
82
402
SPAT1303
SPAT
Counselling and guidance related to growth and development
1.9
7.1
94
483
SGA01
NOMESCO Finland
Emergency treatment
1.8
7.1
124
694
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.9
7.1
91
463
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.6
7.1
40
145
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
12.5
7.0
12
9
Z71.8
ICD-10 Finland
Other specified counselling
1.5
7.0
333
2359
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
7.0
112
611
ZXA10
NOMESCO Finland
Bilateral
1.7
7.0
134
770
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
7.0
109
591
R02
ICPC
Shortness of breath/dyspnoea
1.9
6.9
95
494
P94.2
ICD-10 Finland
Congenital hypotonia
14.7
6.9
11
7
ZXY58
NOMESCO Finland
2-person team, nurse-occupational therapist
14.7
6.9
11
7
G40.39
ICD-10 Finland
Other or unspecified generalized epileptic syndromes with atonic, clonic, myoclonic or tonic-clonic seizures
5.6
6.9
19
32
E11
ICD-10 Finland
Type 2 diabetes mellitus
3.4
6.9
25
70
Q21.10
ICD-10 Finland
Persistent ostium secundum
2.8
6.9
34
115
E23.00
ICD-10 Finland
Panhypopituitarism
18.6
6.8
10
5
U07
ICPC
Urine symptom/complaint other
2.2
6.8
55
235
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.0
6.8
79
388
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
4.4
6.8
17
36
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
4.4
6.8
17
36
IBB02
NOMESCO Finland
Psychiatric evaluation of working capacity and rehabilitation
4.2
6.8
18
40
IEP02
NOMESCO Finland
Child-centred family therapy
2.6
6.8
40
148
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
6.8
84
422
A29
ICPC
General symptom/complaint other
1.8
6.8
105
567
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
6.8
86
436
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
6.8
80
396
Z50.1
ICD-10 Finland
Other physical therapy
3.3
6.8
25
71
SPAT1167
SPAT
Insertion of urinary catheter
11.2
6.7
12
10
F79
ICD-10 Finland
Unspecified mental retardation
11.2
6.7
12
10
R56.0
ICD-10 Finland
Febrile convulsions
2.6
6.7
38
138
SGA02
NOMESCO Finland
Opening and preparing the root canals
2.0
6.7
78
384
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.3
6.7
50
207
C01AA05
ATC
digoxin; systemic
9.3
6.7
13
13
OAA65, ,
SPAT
0.5
6.7
72
1190
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.0
6.6
74
359
N04AA02
ATC
biperiden; systemic
5.6
6.6
18
30
A08.0
ICD-10 Finland
Rotaviral enteritis
3.3
6.6
25
72
P11
ICPC
Eating problem in child
4.1
6.6
18
41
XFE00
NOMESCO Finland
Epicardial ultrasonography
4.3
6.6
17
37
H54.7
ICD-10 Finland
Unspecified visual loss
4.3
6.6
17
37
SPAT1301
SPAT
No procedures
1.5
6.6
255
1730
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
6.6
151
909
Q04.8
ICD-10 Finland
Other specified congenital malformations of brain
12.8
6.6
11
8
H03AA01
ATC
levothyroxine sodium; systemic
1.9
6.6
90
468
P23
ICPC
Adolescent behaviour sympt/compl
2.7
6.6
34
118
SPAT1210
SPAT
Application of cast or individual aid
2.6
6.5
38
140
R49.2
ICD-10 Finland
Hypernasality and hyponasality
37.2
6.5
8
*
R2210
NOMESCO Finland
Guidance to educational rehabilitation
37.2
6.5
8
*
Q02
ICD-10 Finland
Microcephaly
37.2
6.5
8
*
N03AX25
ATC
cenobamate; oral
37.2
6.5
8
*
N05AX13
ATC
paliperidone; systemic
5.9
6.5
17
27
P28
ICPC
Limited function/disability (P)
5.9
6.5
17
27
OAA52, ,
SPAT
10.2
6.5
12
11
Q75.3
ICD-10 Finland
Macrocephaly
15.5
6.5
10
6
SPAT1154
SPAT
Insertion or removal of subcutaneous medicine capsule
3.1
6.5
26
78
C09CA01
ATC
losartan; oral
2.5
6.5
40
152
N05AX16
ATC
brexpiprazole; oral
7.7
6.5
14
17
RS311, ,
NOMESCO Finland
8.7
6.4
13
14
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
8.7
6.4
13
14
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.4
6.4
40
802
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
1.8
6.4
101
548
Q87.14
ICD-10 Finland
Noonan's syndrome
21.0
6.4
9
*
SPAT1312
SPAT
General health counselling
1.4
6.4
380
2798
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.5
6.4
235
1576
F95.2
ICD-10 Finland
Combined vocal and multiple motor tic disorder [de la Tourette]
6.2
6.4
16
24
C09AA02
ATC
enalapril; systemic
2.6
6.4
35
125
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.5
6.4
210
1376
XX4BW, ,
NOMESCO Finland
5.7
6.3
17
28
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
3.0
6.3
28
89
C07AB02
ATC
metoprolol; systemic
2.4
6.3
43
171
Z07
ICPC
Education problem
2.6
6.3
35
126
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.3
6.3
45
183
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.3
6.3
46
189
F42.1
ICD-10 Finland
Predominantly compulsive acts [obsessional rituals]
3.8
6.3
19
47
A10BK03
ATC
empagliflozin; oral
3.8
6.3
19
47
Z93.1
ICD-10 Finland
Gastrostomy status
11.4
6.3
11
9
A10BK01
ATC
dapagliflozin; oral
3.5
6.2
21
56
P70.1
ICD-10 Finland
Syndrome of infant of a diabetic mother
7.3
6.2
14
18
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
6.2
229
1535
Q87.19
ICD-10 Finland
Congenital malformation syndromes predominantly associated with short stature
64.9
6.2
7
*
N05AN01
ATC
lithium; oral
3.1
6.2
26
80
Z04.6
ICD-10 Finland
General psychiatric examination, requested by authority
8.1
6.2
13
15
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.4
6.2
41
161
Z61.8
ICD-10 Finland
Other negative life events in childhood
5.5
6.2
17
29
WGA11, ,
SPAT
0.1
6.1
*
170
S10
ICPC
Boil/carbuncle
2.2
6.1
50
215
WX892
NOMESCO Finland
Monitored bed care
2.0
6.1
65
310
N03AX24
ATC
cannabidiol; oral
13.3
6.1
10
7
1530, ,
Kela drug reimbursment
13.3
6.1
10
7
RS231, ,
NOMESCO Finland
13.3
6.1
10
7
R2110
NOMESCO Finland
Giving the first information
2.4
6.1
41
162
Q87.31
ICD-10 Finland
Syndrome Sotos
+∞
6.1
6
*
F80.3
ICD-10 Finland
Acquired aphasia with epilepsy [Landau-Kleffner]
+∞
6.1
6
*
IHZ02, ,
SPAT
0.2
6.1
6
271
XA820, ,
NOMESCO Finland
6.9
6.0
14
19
H29
ICPC
Ear symptom/complaint other
1.7
6.0
109
616
W11
ICPC
Contraception oral
0.6
6.0
103
1499
E66.8
ICD-10 Finland
Other obesity
2.6
6.0
35
129
D10
ICPC
Vomiting
1.6
6.0
131
778

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
96
132
7.39
60.69
6.4
5.8
435.03
411.08
umol/l
0.63
90
124
259
1093
2.66
35.23
2.9
2.4
258.30
392.48
u/l
0.89
253
1063
491
2888
2.23
30.52
15.5
11.4
1.22
1.22
mmol/l
0.43
462
2663
463
2689
2.20
29.31
18.2
12.5
1.22
1.23
mmol/l
1.20
454
2570
594
3893
2.17
26.53
7.8
6.5
117.96
102.22
u/l
4.81
558
3703
454
2763
2.03
23.73
4.3
3.4
66.65
67.00
nmol/l
0.10
443
2636
153
598
2.64
23.43
16.0
16.3
1.56
1.34
mmol/l
1.43
146
589
290
1526
2.11
22.24
2.9
3.0
2.38
2.39
mmol/l
0.37
276
1422
236
1182
2.14
20.32
12.1
11.4
1.28
1.32
mmol/l
1.16
228
1128
798
6162
2.56
20.21
21.3
12.0
139.72
139.53
mmol/l
1.74
782
5997
797
6169
2.52
19.72
21.2
12.0
3.94
3.92
mmol/l
0.91
777
5979
352
2055
1.95
19.72
7.2
8.2
38.13
38.65
g/l
1.02
338
1962
287
1564
2.01
19.59
6.5
5.3
1.11
1.12
inr
0.05
244
1302
141
581
2.47
19.16
8.8
6.0
734.53
1020.04
ng/l
0.39
118
462
246
1285
2.05
18.76
5.4
4.2
7.39
7.39
ph
0.47
175
860
396
2451
1.87
18.18
10.3
7.3
19.00
18.47
umol/l
0.09
367
2274
517
3482
1.86
18.08
10.5
7.4
6.03
6.12
mmol/l
0.37
492
3212
759
5828
2.20
17.77
5.5
4.4
2.03
1.86
mu/l
4.29
725
5539
223
1149
2.05
17.50
15.4
9.3
7.40
7.41
ph
1.29
195
915
306
1767
1.90
17.22
5.4
4.7
8.41
9.01
mmol/l
1.03
283
1654
30
46
6.19
16.96
2.7
2.8
—
—
—
0
0
190
933
2.11
16.90
3.2
2.1
—
—
—
0
0
70
214
3.19
16.62
7.1
11.4
23.59
23.47
mmol/l
0.12
70
204
684
5105
1.95
16.57
4.9
3.8
14.50
14.54
pmol/l
0.14
647
4677
328
1996
1.81
15.24
4.9
4.5
35.23
31.48
u/l
0.61
315
1902
213
1147
1.93
14.44
16.3
11.4
—
—
—
0
0
24
35
6.48
14.21
2.3
2.8
20.26
13.62
umol/l
1.31
24
35
47
123
3.67
14.18
5.2
6.2
—
—
—
0
0
223
1226
1.90
14.17
4.2
3.1
562.15
585.95
mosm/kgh2o
0.63
195
1084
823
6694
2.37
13.98
12.7
9.2
30.47
27.25
u/l
2.85
806
6530
228
1274
1.87
13.73
10.0
10.0
1.21
1.10
mmol/l
0.23
188
1058
127
577
2.20
13.59
16.6
19.9
1.09
1.04
mg/l
0.58
127
569
91
358
2.50
13.51
1.5
1.6
1060.90
1064.18
nmol/l
0.01
80
272
333
2097
1.73
13.36
6.1
4.2
23.28
48.27
e6/l
0.81
250
1524
25
22
10.76
13.13
1.1
1.4
—
—
—
0
0
231
1313
1.84
13.10
4.5
3.3
9.30
6.77
e6/l
1.02
201
1177
24
869
0.23
12.99
1.3
1.4
3.32
3.43
ratio
0.20
16
596
225
1279
1.83
12.71
10.0
10.2
7.37
7.37
ph
0.18
162
848
171
896
1.94
12.40
13.5
10.9
0.81
0.82
mmol/l
0.72
165
865
611
4578
1.70
12.40
4.5
2.6
5.65
5.40
mmol/l
3.60
574
4258
827
6830
2.25
11.89
16.5
10.3
60.11
64.75
umol/l
7.26
822
6723
382
2560
1.65
11.76
7.4
5.0
110.63
40.87
e6/l
0.90
259
1615
520
3765
1.64
11.74
13.6
11.3
0.00
0.00
e9/l
0.43
415
2881
136
674
2.01
11.52
3.4
4.7
0.22
0.22
g/l
0.01
128
644
355
2348
1.65
11.42
9.1
7.7
—
—
—
0
0
155
807
1.93
11.40
3.1
2.7
327.91
353.67
nmol/l
0.98
147
770
182
1002
1.85
11.26
16.2
8.9
—
—
—
0
0
18
699
0.22
10.83
1.1
1.3
2.88
3.25
mmol/l
—
10
439
297
1903
1.65
10.67
6.0
4.0
0.20
0.23
e6/l
0.14
220
1330
107
501
2.10
10.54
4.4
3.0
—
—
—
0
0
80
333
2.34
10.49
6.9
8.9
359.67
357.33
mg/l
0.01
54
257
21
21
9.42
10.44
1.0
1.3
—
—
—
0
0
46
145
3.03
10.41
2.1
1.4
471.74
349.91
mu/l
1.07
39
117
143
747
1.91
10.36
3.9
4.3
177.00
87.11
mg/l
0.33
109
589
88
388
2.21
10.08
19.6
15.7
-0.00
0.09
mmol/l
0.07
71
329
579
4390
1.60
10.07
5.0
3.4
36.29
35.67
mmol/mol
0.72
547
4214
293
1898
1.63
9.95
5.9
3.9
—
3.96
estimate
—
0
9
231
1409
1.69
9.91
3.6
2.4
—
—
—
0
0
141
748
1.88
9.72
4.8
5.0
6.85
31.02
mg/mmol
0.67
104
580
44
141
2.98
9.69
6.1
8.0
92.67
92.88
%
0.10
44
136
535
4010
1.56
9.53
11.4
9.3
0.59
0.55
e9/l
2.29
450
3336
535
4010
1.56
9.53
11.4
9.3
0.04
0.04
e9/l
0.49
450
3340
178
1023
1.75
9.42
16.9
8.6
23.93
24.05
mmol/l
0.36
178
1016
87
393
2.15
9.39
19.9
15.5
7.41
7.40
ph
0.28
35
138
270
1736
1.62
9.35
7.7
7.4
87.77
87.11
%
0.17
264
1716
36
105
3.25
9.27
6.7
6.7
2.20
1.83
mmol/l
0.33
22
55
413
2938
1.54
9.19
10.1
10.1
—
—
—
0
0
177
1024
1.74
9.13
1.9
1.4
16.43
18.81
nmol/l
1.71
161
923
9
0
+∞
9.11
4.9
0.0
341.33
—
umol/l
—
9
0
543
4124
1.53
8.78
12.3
10.0
0.21
0.21
e9/l
0.20
462
3505
200
1223
1.65
8.34
4.3
4.1
—
—
—
0
0
188
1136
1.67
8.20
3.4
2.2
26.01
32.73
ng/l
0.21
99
421
146
2076
0.58
8.12
2.8
1.9
—
—
—
0
0
64
271
2.27
8.09
3.6
3.9
7.31
7.34
ph
0.26
58
209
244
1589
1.57
7.80
4.2
3.4
0.00
0.00
estimate
0.50
87
574
34
780
0.38
7.58
1.2
1.2
—
—
—
0
0
70
318
2.12
7.46
9.2
13.5
0.66
0.63
%
0.27
70
318
537
4146
1.48
7.42
11.4
9.2
2.31
2.28
e9/l
0.21
459
3569
33
105
2.97
7.40
14.4
5.3
—
—
—
0
0
35
116
2.86
7.31
3.3
3.5
17.78
18.14
%
0.27
35
110
557
4341
1.47
7.26
17.2
11.4
3.85
3.62
e9/l
1.57
467
3602
499
3810
1.46
7.21
10.8
9.5
0.59
0.64
%
1.20
483
3657
108
578
1.82
7.19
1.8
1.5
456.28
12835695.47
pmol/l
0.50
98
522
229
2862
0.65
7.10
2.6
2.4
—
—
—
0
0
247
1647
1.53
7.00
1.9
1.6
99.56
97.83
pmol/l
0.25
139
884
217
1409
1.55
6.93
3.2
3.0
52.94
56.17
u/l
0.66
206
1318
48
193
2.37
6.85
1.6
2.1
12.00
8.38
ug/l
0.34
41
162
107
580
1.80
6.83
2.7
2.2
5.84
5.92
u/l
0.04
76
370
142
1960
0.61
6.81
2.1
2.0
—
—
—
0
0
499
3836
1.44
6.78
10.8
9.5
8.36
8.43
%
0.24
483
3672
63
286
2.11
6.74
25.8
17.7
93.91
95.44
%
0.76
63
286
45
177
2.42
6.74
3.2
4.2
5.85
6.49
index
0.07
33
112
136
794
1.68
6.69
8.0
6.4
1.50
1.44
%
0.37
131
761
88
452
1.88
6.67
7.2
6.1
0.14
0.04
%
0.52
29
134
197
1263
1.56
6.62
5.3
3.5
0.96
0.75
e6/l
0.57
115
626
195
1248
1.56
6.60
5.4
3.7
5.15
2.04
e6/l
2.20
114
616
148
889
1.64
6.52
2.2
1.7
—
—
—
0
0
495
3819
1.43
6.47
10.8
9.5
3.03
3.14
%
0.44
480
3654
34
120
2.68
6.35
3.9
2.1
—
—
—
0
0
89
469
1.83
6.23
7.2
6.1
0.00
0.07
%
2.15
25
138
89
474
1.81
6.03
7.3
6.0
1.10
0.60
%
0.58
31
155
77
398
1.86
5.74
2.1
1.7
0.14
0.22
mg/l
1.95
40
181
271
1908
1.44
5.68
1.9
1.9
1.51
1.28
mmol/l
2.99
247
1766
224
1528
1.47
5.52
3.8
2.9
—
—
—
0
0
23
71
3.04
5.48
1.2
1.3
1.59
1.19
promille
0.51
14
56
83
450
1.77
5.31
5.8
5.5
0.82
0.46
%
0.54
28
147
114
676
1.64
5.26
1.5
1.8
—
—
—
0
0
604
4916
1.40
5.26
4.4
3.1
2.67
2.69
mmol/l
0.30
575
4709
80
432
1.78
5.19
2.3
1.9
0.00
0.00
estimate
-0.00
18
115
32
122
2.47
5.17
3.7
8.8
—
—
—
0
0
19
54
3.30
5.16
2.4
3.1
166.21
146.30
ug/g
0.19
19
47
148
939
1.54
5.14
3.6
3.2
13.30
14.51
umol/l
1.31
140
903
140
878
1.56
5.12
3.6
3.2
2.61
2.54
g/l
0.68
134
834
606
4950
1.39
5.05
4.3
3.1
4.29
4.43
mmol/l
4.01
580
4769
262
1869
1.41
5.01
3.9
2.9
—
—
—
0
0
496
3933
1.36
4.92
10.6
9.1
51.82
50.59
%
1.31
485
3817
16
42
3.56
4.89
2.4
5.0
0.59
-0.05
mmol/l
0.48
11
29
598
4887
1.38
4.88
4.1
3.0
1.25
1.38
mmol/l
16.05
568
4683
369
2797
1.37
4.87
4.8
3.2
6.44
6.31
ph
1.60
200
1374
21
66
2.98
4.87
1.2
1.1
280.29
283.70
mg/l
0.05
21
60
504
4015
1.36
4.81
10.9
9.3
33.07
34.41
%
1.77
491
3882
16
44
3.40
4.58
4.3
4.1
174.25
182.23
umol/l
—
8
22
127
799
1.54
4.57
5.3
6.4
5.55
6.63
umol/l
0.59
113
667
41
189
2.05
4.30
2.2
2.0
—
—
—
0
0
41
189
2.05
4.30
2.2
2.0
—
—
—
0
0
41
189
2.05
4.30
2.2
2.0
—
—
—
0
0
41
189
2.05
4.30
2.2
2.0
—
—
—
0
0
491
3935
1.33
4.29
6.6
3.9
232.17
1122.88
e6/l
0.44
12
48
226
1611
1.39
4.26
4.3
2.9
1.02
1.02
kg/l
1.81
149
977
100
606
1.59
4.24
2.0
2.1
2.39
2.40
mmol/l
0.15
84
526
173
1180
1.44
4.18
4.7
3.8
1.11
1.40
mg/l
0.56
137
812
885
7896
2.14
3.98
29.4
16.7
7.19
6.84
e9/l
2.97
853
7609
884
7891
2.09
3.84
29.2
16.6
86.87
87.00
fl
0.32
878
7816
884
7893
2.08
3.80
29.2
16.6
29.11
29.30
pg
2.01
878
7818
884
7893
2.08
3.80
29.3
16.7
4.71
4.69
e12/l
0.28
850
7608
884
7893
2.08
3.80
31.4
17.7
40.51
41.68
%
0.95
878
7817
884
7897
2.06
3.73
30.6
16.9
136.33
136.94
g/l
0.61
879
7823
91
557
1.56
3.71
2.6
2.1
7.39
8.25
iu/l
0.34
63
369
883
7887
2.03
3.69
29.4
16.8
271.53
265.00
e9/l
2.13
854
7616
92
570
1.55
3.57
7.1
5.0
70.91
62.58
e9/l
1.12
58
324
65
370
1.67
3.56
1.9
1.3
—
—
—
0
0
112
725
1.49
3.54
2.0
2.0
—
—
—
0
0
122
804
1.46
3.53
4.0
3.3
20.86
22.91
%
1.30
117
774
13
321
0.36
3.48
1.0
1.0
—
0.56
—
0
14
85
521
1.56
3.46
2.0
1.7
471.61
316.74
mu/l
1.83
77
466
409
3280
1.27
3.21
5.0
3.5
0.04
2.07
estimate
0.48
90
593
20
78
2.40
3.16
3.9
5.9
0.75
0.77
index
0.03
20
78
410
3296
1.27
3.13
4.9
3.5
0.05
0.00
estimate
0.49
87
583
34
166
1.93
3.11
1.1
1.4
383.14
372.95
ug/g
0.11
22
85
14
46
2.84
3.06
1.9
2.5
32.07
31.83
pg
0.07
14
46
19
74
2.40
3.02
1.1
1.7
—
—
—
0
0
107
709
1.45
3.02
2.8
2.3
9.61
12.07
nmol/l
1.73
95
652
13
298
0.39
2.98
1.3
1.4
—
—
—
0
0
78
486
1.53
2.98
3.9
3.6
—
—
—
0
0
234
1765
1.30
2.93
2.7
3.3
2.84
2.45
mg/l
2.22
209
1590
404
3261
1.26
2.92
4.8
3.5
0.00
0.00
estimate
-0.00
93
610
797
7006
1.40
2.86
14.1
8.1
—
—
—
0
0
8
16
4.65
2.85
3.0
3.3
29.13
29.38
%
—
8
16
537
4492
1.25
2.79
3.9
2.7
1.29
1.14
mmol/l
4.24
512
4295
21
89
2.21
2.79
2.2
2.5
3.97
3.21
ug/l
0.08
21
79
21
89
2.21
2.79
7.2
8.9
5.92
5.12
pmol/l
0.44
21
89
19
78
2.28
2.72
4.2
4.1
9.99
2.15
%
—
9
29
44
244
1.70
2.71
2.2
4.2
131.31
372.22
e6/l
0.64
36
166
44
245
1.69
2.67
2.2
4.1
7.62
7.45
e6/l
0.01
34
159
46
666
0.62
2.61
1.6
1.4
—
—
—
0
0
35
184
1.79
2.59
2.7
1.6
—
—
—
0
0
30
151
1.86
2.55
17.3
22.8
11.54
11.64
%
0.06
30
151
504
4213
1.23
2.52
5.3
3.9
39.18
28.73
u/l
3.01
487
4074
9
24
3.49
2.46
3.1
3.3
—
—
—
0
0
41
231
1.67
2.41
2.1
1.8
0.00
0.00
estimate
-0.00
16
90
38
211
1.69
2.36
1.4
1.9
—
—
—
0
0
34
183
1.74
2.35
4.0
3.2
1126.57
1509.35
e6/l
1.43
28
122
103
711
1.38
2.34
5.2
2.5
5.00
4.38
e9/l
0.74
97
640
89
600
1.41
2.32
2.3
2.6
28.68
32.30
u/l
0.60
73
479
24
116
1.94
2.31
2.2
1.7
—
—
—
0
0
116
819
1.35
2.30
5.8
4.4
329.08
308.82
umol/l
1.24
108
785
192
2115
0.80
2.11
2.0
1.8
—
—
—
0
0
26
135
1.80
2.05
3.2
4.2
3.58
3.23
e9/l
0.31
26
135
29
156
1.74
2.04
2.4
3.0
137.79
138.29
g/l
0.04
29
133
14
58
2.25
2.00
1.9
1.9
19.33
19.56
nmol/l
—
6
16
753
6643
1.27
1.98
25.7
15.2
13.31
13.06
%
6.90
740
6555
19
90
1.97
1.96
11.7
8.6
12.53
8.38
mg/l
1.52
19
84
9
30
2.79
1.95
1.0
1.0
—
19.32
—
0
6
20
326
0.56
1.85
1.5
1.2
—
—
—
0
0
22
349
0.57
1.85
1.4
1.6
—
—
—
0
0
27
405
0.60
1.83
1.1
1.1
—
—
—
0
0
16
73
2.04
1.83
1.4
2.0
—
—
—
0
0
20
324
0.56
1.82
1.6
1.2
—
—
—
0
0
9
32
2.61
1.81
3.6
6.6
112.56
208.81
ug/l
—
9
32
14
61
2.14
1.80
1.0
1.1
—
—
—
0
0
19
94
1.88
1.76
3.8
3.9
2.21
0.73
%
0.91
19
82
21
108
1.81
1.74
4.4
2.2
1.58
2.21
mmol/l
0.68
14
87
35
208
1.58
1.73
2.9
2.2
1.02
1.02
ratio
0.27
28
177
18
88
1.91
1.73
1.5
1.7
58.50
198.56
mu/l
0.72
18
82
7
22
2.95
1.72
2.3
2.0
13.14
10.32
mmol/l
—
7
22
11
44
2.32
1.71
2.7
2.2
96.55
96.95
g/l
0.05
11
44
786
6998
1.27
1.70
17.7
11.1
23.26
22.55
mg/l
0.21
630
5127
113
838
1.28
1.62
1.3
1.3
20.00
175.45
titre
—
5
33
23
127
1.69
1.53
1.1
1.0
1.45
1.37
g/l
0.53
23
118
6
19
2.93
1.52
1.7
1.7
—
—
—
0
0
12
53
2.11
1.51
2.7
6.4
4.97
4.92
kpa
0.07
12
53
5
14
3.31
1.49
3.0
2.0
0.60
0.63
mmol/l
—
5
14
18
282
0.58
1.49
1.2
1.2
—
—
—
0
0
20
107
1.74
1.48
1.2
1.0
—
—
—
0
0
49
619
0.72
1.48
1.1
1.2
2.43
2.76
u/ml
0.11
31
442
6
20
2.78
1.44
1.0
1.2
—
—
—
0
0
7
26
2.50
1.43
1.6
2.2
3.91
3.88
mmol/l
—
7
26
32
196
1.53
1.43
2.2
2.2
2.92
3.99
iu/l
0.54
12
91
9
37
2.26
1.39
1.0
1.2
—
—
—
0
0
25
354
0.64
1.38
1.4
1.6
—
—
—
0
0
29
176
1.54
1.36
4.1
3.1
349.57
552.93
e6/l
2.53
23
113
29
176
1.54
1.36
4.0
3.2
0.29
0.36
e9/l
0.34
21
98
51
629
0.73
1.35
1.1
1.2
0.21
1.06
u/ml
3.51
30
432
14
69
1.89
1.34
1.0
1.1
—
—
—
0
0
36
230
1.46
1.33
2.4
4.3
—
—
—
0
0
9
39
2.14
1.32
1.2
1.4
—
—
—
0
0
6
22
2.53
1.30
1.7
1.2
67.83
69.59
umol/l
—
6
22
16
84
1.77
1.28
1.8
3.0
34.56
34.42
mmol/l
0.01
16
84
29
179
1.51
1.27
4.1
3.2
186.30
207.45
e6/l
0.29
23
117
5
17
2.73
1.24
1.2
1.8
—
—
—
0
0
8
34
2.18
1.22
1.3
2.0
1.64
1.54
nmol/l
—
8
34
82
932
0.79
1.20
2.0
1.6
—
—
—
0
0
53
637
0.75
1.20
1.1
1.2
3.55
6.94
u/ml
1.02
33
481
320
2697
1.15
1.18
1.8
1.7
1.77
1.72
g/l
0.25
182
1533
275
2293
1.15
1.18
4.1
3.0
0.34
0.01
estimate
0.48
74
519
6
24
2.32
1.18
1.7
2.3
1.23
1.20
mmol/l
—
6
24
39
489
0.72
1.17
1.5
1.3
89.00
243.77
miu/ml
—
5
243
15
229
0.60
1.16
1.1
1.1
—
—
—
0
0
10
46
2.02
1.16
1.0
1.4
18.37
17.18
umol/l
—
10
40
58
685
0.77
1.16
1.2
1.3
4.58
2.78
u/ml
0.37
37
482
8
36
2.06
1.15
1.6
2.5
9.63
76.87
ug/min
—
8
29
104
799
1.23
1.14
1.5
1.4
170.58
428.73
u/ml
1.49
95
755
154
1634
0.84
1.13
1.6
1.7
—
—
—
0
0
16
88
1.69
1.12
2.3
2.5
—
—
—
0
0
13
67
1.80
1.12
1.2
1.1
21.16
33.82
iu/ml
0.98
13
67
5
19
2.44
1.11
1.2
1.7
—
—
—
0
0
145
1541
0.84
1.09
3.0
3.5
83.92
104.42
ug/g
0.54
114
1258
17
96
1.65
1.09
1.1
1.2
—
—
—
0
0
12
61
1.83
1.08
2.8
2.2
—
—
—
0
0
124
977
1.20
1.07
4.2
2.2
—
—
—
0
0
21
127
1.54
1.04
1.5
1.3
5.19
4.65
u/ml
0.08
16
63
305
2583
1.14
1.03
4.1
3.2
—
—
estimate
—
0
0
20
120
1.55
1.02
1.3
1.3
—
—
—
0
0
5
21
2.21
0.99
1.6
1.2
0.60
0.00
estimate
—
5
21
9
46
1.81
0.97
1.4
1.2
—
—
nmol/l
—
0
0
6
25
2.22
0.93
1.7
2.2
105.17
106.52
mmol/l
—
6
25
339
2908
1.12
0.92
1.7
1.8
2.20
2.98
u/ml
0.25
74
611
8
40
1.85
0.87
1.3
2.1
—
—
—
0
0
47
343
1.28
0.84
1.7
1.8
0.82
0.89
ug/l
0.36
38
310
13
74
1.63
0.83
2.8
2.4
—
—
—
0
0
30
367
0.75
0.82
1.1
1.1
—
20.57
—
0
59
30
206
1.36
0.82
1.3
1.2
93.17
225.14
iu/ml
—
6
58
39
279
1.30
0.81
3.5
2.9
49.13
53.41
%
1.07
39
279
104
830
1.18
0.81
4.8
3.3
2837.98
1100.31
ng/l
0.48
59
429
53
397
1.25
0.78
1.5
1.2
—
—
—
0
0
73
797
0.83
0.78
1.3
1.2
1.15
6.53
u/ml
2.89
26
271
87
687
1.19
0.77
1.4
1.3
71.22
123.67
u/ml
0.65
21
228
13
183
0.65
0.77
1.1
1.5
0.33
0.55
ug/l
—
7
45
23
153
1.40
0.76
1.7
1.2
—
—
—
0
0
188
1578
1.13
0.74
8.1
5.0
—
—
—
0
0
81
869
0.85
0.72
1.3
1.2
35.88
14.97
iu/ml
0.38
11
177
9
54
1.54
0.69
2.1
3.3
1050.44
664.69
u/ml
—
9
54
5
25
1.85
0.68
1.6
1.2
345.80
148.47
mmol/24h
—
5
25
25
173
1.34
0.67
2.8
5.3
—
—
—
0
0
38
280
1.26
0.66
1.8
1.6
0.21
0.21
g/l
0.03
38
268
68
534
1.19
0.66
1.4
1.4
—
—
—
0
0
5
26
1.78
0.65
1.2
1.2
—
—
—
0
0
10
57
1.63
0.65
1.9
3.9
21.46
28.58
ug/l
—
10
52
10
57
1.63
0.65
4.2
3.4
—
—
—
0
0
23
158
1.35
0.65
1.3
1.2
—
—
—
0
0
31
225
1.28
0.62
1.0
1.0
3.41
3.29
kpa
0.15
25
192
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
8
48
1.54
0.59
3.0
3.8
49.94
50.01
%
—
8
40
94
769
1.14
0.57
3.3
2.6
12110.28
6190.39
u/l
0.34
24
283
31
228
1.26
0.57
1.0
1.0
—
—
—
0
0
31
228
1.26
0.57
1.0
1.0
-2.06
-2.64
mmol/l
—
9
50
31
228
1.26
0.57
1.0
1.0
6.88
7.37
kpa
0.73
25
194
5
82
0.56
0.56
1.0
1.6
8.90
7.42
mmol/l
—
5
82
86
897
0.87
0.56
1.8
1.5
—
—
—
0
0
103
851
1.13
0.54
4.9
2.9
—
—
—
0
0
9
55
1.52
0.54
1.1
1.6
—
—
—
0
0
6
36
1.54
0.53
1.7
1.3
—
—
—
0
0
23
165
1.29
0.52
1.1
1.1
—
—
—
0
0
17
206
0.76
0.48
1.0
1.1
6.44
6.30
eliau/ml
—
5
73
21
151
1.29
0.47
2.9
4.0
—
—
—
0
0
18
127
1.32
0.46
3.7
3.6
2.60
1.97
ug/l
0.28
11
68
257
2504
0.93
0.46
1.6
1.7
—
—
—
0
0
41
444
0.85
0.45
1.2
1.1
8.80
7.42
u/ml
0.16
25
293
7
46
1.41
0.45
2.0
1.1
—
—
—
0
0
7
46
1.41
0.45
2.0
1.1
—
—
—
0
0
7
46
1.41
0.45
2.0
1.1
—
—
—
0
0
30
228
1.22
0.44
1.2
1.4
—
—
—
0
0
28
314
0.82
0.44
5.3
4.3
10.54
8.41
umol/l
0.42
22
259
179
1766
0.92
0.44
3.8
2.7
0.69
0.00
estimate
0.49
72
502
0
14
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.40
0.0
1.2
—
—
—
0
0
0
16
0.00
0.40
0.0
3.3
—
13.34
—
0
16
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
21
239
0.81
0.39
1.6
1.7
16.15
9.63
u/ml
—
6
67
38
405
0.86
0.36
1.4
1.2
—
—
—
0
0
22
166
1.23
0.36
1.0
1.1
—
—
—
0
0
46
373
1.15
0.35
2.7
2.1
—
—
—
0
0
6
39
1.42
0.35
1.0
1.1
—
68.80
—
0
5
133
1148
1.08
0.34
3.6
2.2
—
—
—
0
0
30
237
1.17
0.32
1.1
1.2
—
—
—
0
0
41
336
1.13
0.29
2.0
1.6
—
—
—
0
0
33
347
0.87
0.28
1.7
1.3
—
—
—
0
0
12
87
1.28
0.27
1.0
1.3
—
—
—
0
0
39
404
0.89
0.27
1.1
1.1
1.30
0.38
u/ml
0.33
20
208
27
216
1.16
0.26
1.4
1.1
—
—
—
0
0
29
305
0.87
0.25
1.9
1.8
32.79
35.65
nmol/l
0.31
29
297
9
71
1.17
0.24
1.3
1.2
88.89
121.65
pmol/l
—
9
71
51
515
0.91
0.24
1.1
1.2
—
—
—
0
0
41
419
0.90
0.24
1.1
1.1
6.63
10.84
u/ml
0.64
23
269
43
438
0.90
0.24
2.4
1.9
6.16
6.38
ph
1.20
32
270
15
165
0.84
0.22
1.3
1.5
94.96
12.43
u/ml
—
9
132
0
10
0.00
0.21
0.0
5.0
—
2.70
—
0
10
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
8
95
0.78
0.21
1.0
1.3
—
69.17
—
0
6
0
12
0.00
0.21
0.0
1.0
—
0.07
—
0
7
0
12
0.00
0.21
0.0
1.1
—
83.31
—
0
12
15
163
0.85
0.20
1.9
2.2
27.93
38.54
u/ml
0.46
15
157
43
364
1.10
0.19
2.8
2.1
118.30
107.64
au/ml
0.24
20
136
6
47
1.18
0.19
1.2
1.1
134.20
230.99
iu/ml
—
6
47
107
940
1.06
0.19
1.5
1.6
496.67
494.60
titre
0.00
12
126
6
48
1.16
0.19
1.0
1.1
—
—
—
0
0
11
122
0.83
0.18
1.2
1.1
—
—
—
0
0
57
491
1.08
0.18
2.0
2.0
—
—
—
0
0
25
257
0.90
0.17
1.6
1.7
11.80
4.62
iu/ml
—
5
44
8
65
1.14
0.16
1.5
1.3
—
—
—
0
0
8
66
1.12
0.16
1.1
1.1
—
—
—
0
0
20
164
1.13
0.15
2.5
2.3
—
—
—
0
0
7
82
0.79
0.14
2.7
1.6
—
—
—
0
0
24
244
0.91
0.14
1.1
1.5
3.26
3.58
u/ml
0.04
18
170
24
201
1.11
0.14
1.3
1.1
3.44
6.91
iu/ml
—
7
30
24
201
1.11
0.14
1.3
1.2
—
—
—
0
0
9
99
0.84
0.13
1.4
2.4
11.81
9.68
mg/l
—
9
93
13
106
1.13
0.10
1.0
1.1
—
—
—
0
0
5
40
1.16
0.10
1.0
1.3
—
—
—
0
0
5
43
1.07
0.09
1.2
1.0
—
—
—
0
0
399
3725
0.98
0.09
4.0
3.5
68.27
60.60
ug/l
0.71
378
3558
6
50
1.11
0.09
1.0
1.0
—
—
—
0
0
130
1228
0.97
0.08
3.8
2.0
—
—
—
0
0
63
562
1.04
0.07
2.7
2.0
—
—
—
0
0
6
69
0.80
0.07
1.0
1.0
—
—
—
0
0
6
69
0.80
0.07
1.3
1.1
—
—
—
0
0
9
80
1.04
0.07
1.3
1.1
—
—
—
0
0
14
119
1.09
0.05
3.4
2.7
11.41
25.75
mg/l
—
9
79
15
129
1.07
0.04
3.7
4.3
—
—
—
0
0
15
148
0.93
0.04
1.3
1.3
—
—
—
0
0
135
1230
1.02
0.04
3.8
2.1
—
—
—
0
0
23
203
1.05
0.03
1.3
1.7
—
12.06
—
0
5
135
1233
1.01
0.03
3.8
2.1
—
—
—
0
0
10
85
1.09
0.03
1.0
1.3
—
—
—
0
0
52
490
0.98
0.02
2.3
1.9
188.22
165.98
u/ml
0.32
32
253
14
122
1.06
0.02
1.1
1.5
—
198.85
—
0
26
14
122
1.06
0.02
1.1
1.5
—
242.86
—
0
7
135
1238
1.01
0.01
3.9
2.2
—
—
—
0
0
51
464
1.02
0.01
1.6
1.7
—
—
—
0
0
131
1203
1.01
0.01
1.2
1.3
—
—
—
0
0
28
258
1.00
0.00
1.2
1.2
—
—
—
0
0
152
1402
1.00
0.00
2.0
1.7
—
—
—
0
0
41
381
0.99
0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
302.13
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
85
0.98
-0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
5
47
0.98
-0.00
1.6
1.2
—
—
—
0
0
6
64
0.86
-0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.91
-0.00
1.0
1.1
1579.67
1538.57
miu/ml
—
6
61
5
50
0.92
-0.00
1.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
64
0.86
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
18.14
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
63.36
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
28.40
—
0
8
6
55
1.01
-0.00
3.5
3.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
56.86
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
0.02
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
52
0.89
-0.00
1.0
1.3
—
19.43
—
0
14
0
5
0.00
-0.00
0.0
8.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint F5_MIXEDDEV and mortality.

Females

Parameter HR [95% CI] p-value
F5_MIXEDDEV 3.661 [2.58, 5.2] < 0.001
Birth year 0.99 [0.98, 1.0] 0.032

During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 8685 females with F5_MIXEDDEV died.

Males

Parameter HR [95% CI] p-value
F5_MIXEDDEV 2.156 [1.77, 2.62] < 0.001
Birth year 0.987 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 146 out of 19887 males with F5_MIXEDDEV died.

Mortality risk

Mortality risk for people of age

years, who have F5_MIXEDDEV.

N-year risk Females Males
1 0.259% 0.317%
5 1.439% 2.249%
10 4.139% 6.384%
15 8.235% 11.432%
20 14.601% 18.666%

Relationships between endpoints

Index endpoint: F5_MIXEDDEV – Mixed specific developmental disorders

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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