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Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

C3_PRIMARY_LYMPHOID_HEMATOPOIETIC_NAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C96
  • Hospital discharge: ICD-9 202
  • Hospital discharge: ICD-8 202
  • Cause of death: ICD-10 C96
  • Cause of death: ICD-9 202
  • Cause of death: ICD-8 202

2 out of 7 registries used, show all original rules.

395

4. Check minimum number of events

None

395

5. Include endpoints

None

395

6. Filter based on genotype QC (FinnGen only)

330

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
C81-C96
Name in latin
Neoplasmata maligna alia et non specificata textus lymphatici, haematopoetici et cognati

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 330 153 177
Unadjusted period prevalence (%) 0.07 0.05 0.08
Median age at first event (years) 59.30 56.22 61.97

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
342
Matched controls
3420
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
41.4
261.9
189
99
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
+∞
196.4
169
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
32.6
82.7
55
20
XW000
NOMESCO Finland
Bone marrow biopsy
13.4
81.8
87
85
L03AA02
ATC
filgrastim; parenteral
16.7
75.5
68
50
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
25.1
60.6
44
20
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
9.3
52.1
70
92
20298
ICD-8 Finland
Other neoplasms of lymphoid tissue, Lymphomata alia
+∞
45.9
43
*
A04AA01
ATC
ondansetron; systemic, rectal
5.8
36.7
79
169
A03FA01
ATC
metoclopramide; systemic, rectal
4.1
34.8
143
510
JN4BD
NOMESCO Finland
Extensive body CT
4.9
34.3
94
247
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.7
34.2
60
105
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
9.6
32.9
41
48
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
9.4
30.2
38
45
WW500
NOMESCO Finland
Blood transfusion
6.7
29.1
50
85
M04AA01
ATC
allopurinol; systemic
4.1
28.4
100
314
C96.2
ICD-10 Finland
Malignant mast cell tumour
+∞
27.5
26
*
JN4AD
NOMESCO Finland
Body CT examination
4.1
26.4
88
265
20199
ICD-8 Finland
Hodgkin's disease
+∞
25.3
24
*
R50.9
ICD-10 Finland
Fever, unspecified
3.6
23.4
98
343
H02AB02
ATC
dexamethasone; systemic
3.8
22.4
81
256
Q82.2
ICD-10 Finland
Mastocytosis
+∞
22.1
21
*
C96.7
ICD-10 Finland
Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
+∞
22.1
21
*
JN6AD
NOMESCO Finland
CT of torso and neck
9.3
20.9
26
30
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
117.2
20.8
22
*
ZX120
NOMESCO Finland
Intravenous
3.8
19.4
68
209
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
21.7
19.4
28
14
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
5.7
19.1
38
74
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
20.2
19.0
28
15
PJA10
NOMESCO Finland
Exploration of lymph nodes
20.2
19.0
28
15
Z85.7
ICD-10 Finland
Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
200.5
18.7
19
*
1XC02, ,
NOMESCO Finland
44.6
17.5
21
5
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
44.6
17.5
21
5
H02AB06
ATC
prednisolone; systemic
2.7
17.2
208
1259
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
13.1
16.7
29
24
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
15.5
16.1
26
18
L03AA13
ATC
pegfilgrastim; parenteral
4.7
15.7
38
88
WF049
NOMESCO Finland
Radiotherapy of metastasis
5.2
15.1
32
66
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
14.8
74
282
WZC00
NOMESCO Finland
Treatment plan or consultation
2.4
14.0
153
859
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
55.7
13.9
16
*
N02AA05
ATC
oxycodone; systemic
2.6
13.7
103
486
XX9CD
NOMESCO Finland
Very extensive complementary CT
+∞
13.6
13
*
20293
ICD-8 Finland
Other neoplasms of lymphoid tissue, Neoplasma benignum sive NUD medullae osseae
+∞
13.6
13
*
A02BC02
ATC
pantoprazole; systemic
2.7
13.6
269
1959
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
13.5
73
290
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
17.6
13.1
20
12
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
14.8
12.9
21
15
C82.1
ICD-10 Finland
Follicular lymphoma grade II
25.5
12.6
17
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
12.5
208
1377
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
39.1
12.3
15
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
17.8
11.3
17
10
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
3.6
11.0
38
114
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.6
10.9
38
115
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
29.1
10.8
14
5
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
29.1
10.8
14
5
WF004
NOMESCO Finland
Palliative radiotherapy
9.0
10.7
22
26
D47.0
ICD-10 Finland
Histiocytic and mast cell tumours of uncertain and unknown behaviour
62.0
10.7
12
*
C91.4
ICD-10 Finland
Hairy-cell leukaemia
62.0
10.7
12
*
9940/3-C42.1
ICD-O-3
Hairy cell leukemia, NOS, of bone marrow
62.0
10.7
12
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
10.6
87
422
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
113.4
10.5
11
*
2024A
ICD-9 Finland
Other malignant neoplasm of lymphoid and histiocytic tissue, Leukaemic reticuloendotheliosis
+∞
10.5
10
*
C81.0
ICD-10 Finland
Nodular lymphocyte predominant Hodgkin lymphoma
+∞
10.5
10
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
18.2
9.5
14
8
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
31.0
9.5
12
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
31.0
9.5
12
*
20228
ICD-8 Finland
Other neoplasms of lymphoid tissue, Other primary malignant neoplasms of lymphoid tissue
+∞
9.4
9
*
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
11.9
9.2
16
14
Z51.5
ICD-10 Finland
Palliative care
2.7
9.1
53
217
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.7
9.0
21
47
R06AE07
ATC
cetirizine; oral
2.0
8.6
149
957
ZXE00
NOMESCO Finland
One hour or less
2.0
8.5
145
925
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
8.4
97
537
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
4.0
8.4
24
63
C81.7
ICD-10 Finland
Other classical Hodgkin lymphoma
+∞
8.4
8
*
9650/3-C77.0
ICD-O-3
Hodgkin lymphoma, NOS, of lymph nodes of head, face and neck
+∞
8.4
8
*
B01AB10
ATC
tinzaparin; parenteral
2.6
8.3
53
227
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
8.3
58
260
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.7
8.2
19
42
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
12.1
8.1
14
12
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
13.5
7.9
13
10
C90.0
ICD-10 Finland
Multiple myeloma
8.8
7.9
16
19
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
7.9
45
182
R4110
NOMESCO Finland
Physiotherapy
2.0
7.6
111
667
D70.82
ICD-10 Finland
Drug-induced neutropenia
6.7
7.5
18
28
Z2221
NOMESCO Finland
Medical doctor
2.0
7.5
104
614
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
81.8
7.4
8
*
C96.6
ICD-10 Finland
Unifocal Langerhans-cell histiocytosis
+∞
7.3
7
*
9590/3-C80.9
ICD-O-3
Malignant lymphoma, NOS, of unknown primary site
+∞
7.3
7
*
C96.0
ICD-10 Finland
Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis [Letterer-Siwe disease]
+∞
7.3
7
*
9741/3-C42.1
ICD-O-3
Malignant mastocytosis of bone marrow
+∞
7.3
7
*
2029X
ICD-9 Finland
Other malignant neoplasm of lymphoid and histiocytic tissue, Other and unspecified malignant neoplasms of lymphoid and histiocytic tissue
+∞
7.3
7
*
9591/3-C77.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph node, NOS
+∞
7.3
7
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
7.2
71
367
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.5
7.2
49
216
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
20.5
7.2
10
5
ZX090
NOMESCO Finland
Other technic of radiotherapy
3.8
7.1
22
61
WX892
NOMESCO Finland
Monitored bed care
2.7
7.0
38
150
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
6.8
55
262
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
40.9
6.8
8
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
17.1
6.8
10
6
WF003
NOMESCO Finland
Adjuvant radiotherapy
3.9
6.7
20
54
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
12.6
6.6
11
9
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.0
6.6
84
478
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
6.4
6.5
16
26
H02AB07
ATC
prednisone; oral
2.2
6.5
57
281
C81.2
ICD-10 Finland
Mixed cellularity classical Hodgkin lymphoma
71.1
6.4
7
*
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
71.1
6.4
7
*
B01AB05
ATC
enoxaparin; parenteral
1.8
6.3
125
821
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
6.3
135
908
2015X
ICD-9 Finland
Hodgkin's disease, Nodular sclerosis[MORBUS HODGKIN, NODULAR SCLEROSIS, NUD]
+∞
6.3
6
*
D76.3
ICD-10 Finland
Other histiocytosis syndromes
+∞
6.3
6
*
I88.8
ICD-10 Finland
Other nonspecific lymphadenitis
+∞
6.3
6
*
C96.1
ICD-10 Finland
Malignant histiocytosis
+∞
6.3
6
*
9691/3-C77.9
ICD-O-3
Follicular lymphoma, grade 2 of lymph node, NOS
+∞
6.3
6
*
GD1AD
NOMESCO Finland
Thorax CT examination
2.8
6.3
32
122
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
6.9
6.1
14
21

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
67
27
30.62
97.71
1.4
1.2
—
—
—
0
0
75
45
21.07
92.87
1.5
1.2
—
—
—
0
0
122
201
8.88
76.91
1.3
1.4
—
—
—
0
0
142
310
7.12
67.95
1.4
1.5
—
—
—
0
0
65
70
11.23
56.37
1.7
1.9
—
—
—
0
0
141
386
5.51
50.99
1.6
1.5
—
—
—
0
0
117
277
5.90
49.76
1.8
1.4
—
—
—
0
0
148
438
5.19
48.42
1.7
1.9
—
—
—
0
0
232
1031
4.89
43.88
11.7
6.0
—
—
—
0
0
191
811
4.07
36.53
5.6
2.9
335.59
351.30
umol/l
0.98
184
705
99
260
4.95
36.30
5.0
2.6
10.53
10.65
g/l
0.04
93
242
266
1441
4.81
35.49
12.4
6.4
0.71
0.65
%
0.81
258
1349
266
1446
4.78
35.19
12.5
6.5
9.66
9.04
%
1.58
259
1363
62
110
6.66
34.87
4.5
3.6
2.15
2.61
ratio
0.23
32
56
265
1443
4.72
34.81
12.4
6.4
2.77
2.74
%
0.07
258
1356
268
1475
4.78
34.59
12.5
6.5
27.07
26.59
%
0.23
261
1398
64
122
6.22
33.45
5.1
4.0
47.22
46.00
mg/l
0.02
54
104
127
428
4.13
33.30
3.6
2.9
1.65
1.82
%
1.32
118
383
273
1560
4.72
32.51
11.5
6.2
0.04
0.04
e9/l
0.13
238
1324
272
1552
4.68
32.41
11.6
6.2
0.63
0.60
e9/l
0.92
237
1314
63
122
6.10
32.35
5.1
4.0
65.61
100.47
mg/l
0.31
53
104
276
1602
4.75
31.84
12.4
6.4
0.17
0.19
e9/l
1.00
249
1389
274
1588
4.65
31.53
11.7
6.3
1.97
1.89
e9/l
0.15
249
1396
42
56
8.41
30.41
1.5
1.3
—
—
—
0
0
39
48
9.04
30.09
1.5
1.2
153.08
137.93
au/ml
0.25
19
14
87
239
4.54
29.69
3.7
2.5
—
—
—
0
0
284
1731
4.78
29.42
23.6
10.1
4.01
4.19
e9/l
0.22
261
1505
251
1430
3.84
28.11
10.0
5.1
33.57
35.13
g/l
3.97
245
1340
102
329
3.99
27.89
4.1
3.0
64.23
68.87
e9/l
0.51
73
238
46
75
6.93
27.85
1.5
1.2
—
—
—
0
0
136
548
3.46
26.37
5.5
3.2
0.80
0.82
mmol/l
0.68
128
521
77
212
4.40
25.98
3.8
1.6
2.57
1.44
g/l
0.49
71
191
190
967
3.17
24.43
7.6
4.7
—
—
—
0
0
191
983
3.14
23.94
8.3
4.1
7.41
7.40
ph
2.63
151
695
117
454
3.40
23.74
6.9
5.6
1.04
1.04
mmol/l
0.04
112
414
149
677
3.13
23.07
6.2
3.0
2.50
2.45
mmol/l
3.70
143
615
123
504
3.25
22.68
2.6
2.5
21.12
22.42
%
0.49
118
478
33
47
7.66
22.46
1.4
1.1
237.05
343.48
u/ml
0.59
20
21
242
1463
3.24
22.18
11.0
6.9
1.21
1.21
mmol/l
0.00
237
1341
127
540
3.15
21.86
2.5
2.5
2.11
2.26
g/l
2.35
119
503
133
581
3.11
21.84
2.6
2.5
11.66
12.78
umol/l
0.92
126
544
254
1615
3.23
20.60
12.4
7.8
1.22
1.21
mmol/l
0.58
222
1404
58
158
4.22
19.57
2.0
2.1
1.40
1.49
g/l
0.25
48
142
194
1100
2.76
18.87
7.7
3.5
2.35
2.35
mmol/l
0.18
181
995
219
1332
2.79
18.37
21.1
12.7
0.01
0.00
e9/l
0.60
185
1074
37
78
5.20
17.03
2.0
1.9
—
—
—
0
0
29
24
13.09
16.67
2.3
1.9
28.84
36.83
%
1.41
29
24
77
292
3.11
15.58
8.4
5.0
1.29
0.92
%
0.49
54
107
23
13
18.85
15.37
3.6
1.4
3172.22
868.62
u/ml
1.43
23
13
25
41
6.50
14.88
1.3
1.1
—
—
—
0
0
153
852
2.44
14.33
3.8
3.3
—
0.00
estimate
—
0
6
72
277
3.03
14.12
9.1
4.9
0.86
0.49
%
1.06
49
95
159
911
2.39
13.86
17.3
6.2
—
—
—
0
0
71
274
3.01
13.83
8.8
5.1
0.29
0.13
%
0.68
48
87
73
290
2.93
13.48
6.8
7.1
11.51
10.20
mmol/l
0.59
68
276
81
343
2.78
13.28
3.8
4.0
1.56
1.82
mmol/l
0.24
68
287
150
855
2.34
13.04
2.3
2.2
2.89
2.94
mg/l
0.11
133
737
40
112
3.91
12.86
2.7
2.2
21.45
21.30
s
0.06
40
105
156
909
2.32
12.82
4.1
3.4
0.39
0.49
e6/l
0.29
124
670
83
365
2.68
12.59
3.9
4.1
7.38
7.38
ph
0.22
51
218
203
1344
2.26
12.00
4.4
3.0
341.28
140.01
ug/l
2.90
197
1241
210
1425
2.23
11.48
4.4
3.0
—
—
estimate
—
0
0
125
690
2.28
11.41
2.2
1.7
3.38
1.43
mg/l
0.78
104
548
225
1575
2.25
11.31
21.7
15.9
1.38
1.30
inr
1.24
193
1311
69
294
2.69
11.04
7.4
9.5
—
—
—
0
0
165
1031
2.16
10.96
4.5
2.5
—
—
—
0
0
291
2300
2.78
10.77
20.5
8.6
90.03
80.38
u/l
2.26
286
2174
168
1064
2.14
10.70
4.2
3.5
41.57
122.99
e6/l
0.69
134
825
96
486
2.36
10.62
1.7
2.1
—
—
—
0
0
80
376
2.47
10.42
4.8
3.1
8.79
8.25
umol/l
0.09
75
334
65
281
2.62
10.05
9.0
5.4
0.07
0.20
%
0.50
42
81
18
18
10.49
9.64
2.9
2.8
35.00
48.60
%
—
10
10
15
11
14.19
9.26
1.2
1.1
—
—
—
0
0
111
627
2.14
9.25
3.0
1.4
2.24
2.60
g/l
0.56
79
370
113
644
2.13
9.19
5.0
3.8
247.82
335.46
ng/l
0.22
95
536
173
1176
1.95
8.43
2.7
2.2
—
—
—
0
0
111
648
2.06
8.35
3.6
3.0
493.12
550.77
mosm/kgh2o
2.45
101
564
20
31
6.78
8.31
1.1
1.3
—
—
—
0
0
110
645
2.04
8.14
9.6
5.5
—
—
—
0
0
21
51
4.32
8.12
1.6
1.4
—
—
—
0
0
21
51
4.32
8.12
1.6
1.4
—
—
—
0
0
21
51
4.32
8.12
1.6
1.4
—
—
—
0
0
21
51
4.32
8.12
1.6
1.4
—
—
—
0
0
242
1866
2.02
7.92
7.9
5.4
6.60
6.72
mmol/l
0.37
234
1780
33
112
3.15
7.90
1.2
1.4
—
—
—
0
0
93
518
2.09
7.88
3.6
3.3
1.77
1.85
e6/l
0.05
49
258
171
1182
1.89
7.70
5.4
4.2
428.60
128.49
e6/l
0.39
133
850
13
11
12.23
7.64
2.5
1.5
40.85
32.91
%
0.46
13
11
62
302
2.29
7.30
2.8
2.3
33.82
33.11
u/l
0.05
49
245
66
332
2.22
7.19
2.2
2.3
0.19
0.21
g/l
1.22
61
310
19
47
4.22
7.18
1.2
1.0
—
—
—
0
0
16
24
6.94
6.89
1.4
1.3
—
—
—
0
0
118
750
1.88
6.69
3.3
2.8
7.02
5.17
e6/l
0.37
110
685
84
476
2.01
6.68
7.5
7.5
103.87
104.12
mmol/l
0.17
84
476
19
50
3.96
6.63
1.2
1.1
—
—
—
0
0
52
245
2.32
6.59
3.8
3.8
80.85
85.79
ng/l
0.18
44
214
37
149
2.66
6.53
2.2
3.5
453.04
1611.01
u/ml
0.62
27
130
189
1401
1.78
6.35
2.5
2.2
88.22
94.72
pmol/l
1.26
117
735
147
1013
1.79
6.33
2.9
2.6
56.03
65.58
u/l
0.52
135
942
16
39
4.25
6.15
2.8
2.3
—
—
—
0
0
120
786
1.81
6.08
1.6
1.4
—
—
—
0
0
95
580
1.88
6.01
1.7
1.7
1018.46
1199.07
nmol/l
1.51
76
428
40
175
2.46
5.96
1.3
1.2
384.25
298.31
u/ml
0.18
33
159
66
365
2.00
5.56
2.5
4.6
41.41
39.47
ug/l
0.02
50
306
180
1353
1.70
5.44
3.0
2.5
78.94
77.98
nmol/l
0.18
169
1189
69
393
1.95
5.33
1.6
1.3
1556.92
561.25
titre
0.98
13
96
18
54
3.46
5.24
1.1
1.7
—
—
—
0
0
21
70
3.13
5.20
4.0
3.0
53.05
58.88
%
0.77
21
70
17
50
3.53
5.09
4.2
2.9
3.29
4.52
e9/l
1.97
17
50
20
66
3.16
5.03
1.2
1.5
12.00
18.50
e6/l
0.19
13
48
139
993
1.67
4.97
1.8
1.7
16.96
20.74
nmol/l
3.11
122
821
14
29
4.99
4.86
1.1
1.4
—
—
—
0
0
20
68
3.06
4.80
1.2
1.6
31.43
192.28
e6/l
0.87
14
50
148
1096
1.62
4.47
4.4
3.2
1904.96
1577.84
ng/l
0.50
136
930
19
66
2.99
4.40
1.1
1.1
—
—
—
0
0
62
372
1.81
4.04
1.7
1.8
—
—
—
0
0
20
76
2.73
3.97
1.4
1.3
—
—
—
0
0
14
38
3.80
3.84
6.9
4.2
—
—
—
0
0
12
29
4.25
3.74
1.1
1.1
—
—
—
0
0
8
12
6.79
3.69
2.6
1.6
39.50
60.33
ug/l
—
8
12
9
16
5.74
3.68
2.0
1.4
—
—
—
0
0
63
392
1.74
3.63
1.3
1.3
—
—
—
0
0
14
46
3.13
3.57
4.5
3.1
—
—
—
0
0
14
46
3.13
3.57
1.4
1.8
—
—
—
0
0
11
26
4.34
3.53
1.0
1.8
—
—
—
0
0
12
32
3.85
3.42
3.4
3.0
310.08
1190.06
mg
1.88
12
32
65
417
1.69
3.35
1.6
1.3
—
—
—
0
0
131
994
1.52
3.33
3.8
3.4
—
—
—
0
0
10
24
4.26
3.22
1.0
1.1
—
—
—
0
0
13
40
3.34
3.17
1.5
1.6
—
—
—
0
0
62
399
1.68
3.15
7.7
9.5
7.42
7.41
ph
0.52
37
235
20
86
2.41
3.14
3.3
3.7
0.65
2.09
index
1.33
14
55
11
30
3.75
3.11
1.0
2.0
—
—
—
0
0
234
2022
1.50
3.00
5.8
4.8
—
1.81
—
0
5
62
407
1.64
2.92
7.7
9.2
5.07
5.11
kpa
0.13
62
392
62
407
1.64
2.92
7.7
9.2
11.92
11.87
kpa
0.02
62
394
7
14
5.08
2.74
2.7
1.4
—
—
—
0
0
24
119
2.09
2.73
2.3
2.2
5.53
8.35
iu/ml
—
6
37
72
997
0.65
2.72
3.7
3.4
—
—
—
0
0
6
10
6.08
2.71
1.3
1.4
5.55
12.03
mu/l
—
6
10
27
142
1.98
2.64
1.4
1.3
—
—
—
0
0
12
42
2.92
2.57
1.1
1.1
2.83
4.06
u/ml
—
6
16
59
397
1.59
2.51
7.8
9.5
0.44
1.01
mmol/l
0.46
53
335
19
89
2.20
2.50
1.2
1.2
—
—
—
0
0
7
16
4.44
2.48
1.0
1.0
—
—
—
0
0
10
32
3.19
2.45
2.4
2.0
—
—
—
0
0
18
84
2.21
2.39
1.2
1.4
24.39
24.03
iu/l
0.02
12
72
16
71
2.32
2.38
1.8
1.2
9.01
7.59
u/l
0.14
11
56
9
28
3.27
2.32
1.4
1.6
21.14
38.09
ng/l
—
9
28
38
233
1.71
2.32
5.0
3.9
—
—
—
0
0
10
34
3.00
2.30
1.6
1.5
—
—
—
0
0
11
40
2.81
2.29
4.5
1.5
—
—
—
0
0
6
13
4.68
2.28
1.0
1.0
—
—
—
0
0
51
340
1.59
2.26
8.8
10.2
116.39
119.47
g/l
0.48
51
334
6
14
4.34
2.16
1.3
3.4
110.00
65.07
nmol/l
—
6
14
10
36
2.83
2.15
1.9
1.9
89.07
89.31
%
—
10
36
54
370
1.55
2.14
8.2
9.7
94.87
95.22
%
0.11
54
360
32
192
1.74
2.12
11.4
12.1
15.55
15.57
%
0.01
32
185
8
26
3.13
2.02
3.8
2.2
—
—
—
0
0
262
2819
0.70
2.02
5.9
6.2
2.47
2.61
mmol/l
1.67
235
2587
255
2753
0.71
1.96
5.0
5.3
1.33
1.45
mmol/l
5.31
229
2520
10
39
2.61
1.95
1.0
1.1
—
—
—
0
0
56
396
1.50
1.92
4.7
3.1
3.65
5.15
e9/l
1.44
46
343
257
2767
0.71
1.89
5.1
5.4
4.28
4.50
mmol/l
2.98
235
2551
6
17
3.57
1.84
1.7
2.5
—
—
—
0
0
25
147
1.76
1.79
1.3
1.3
—
—
—
0
0
8
30
2.71
1.73
1.3
1.0
—
—
—
0
0
10
40
2.54
1.68
1.7
1.5
5208.00
27019.18
e6/l
—
5
22
149
1272
1.30
1.62
5.0
4.2
27.58
40.60
ng/l
1.49
115
984
300
2831
1.49
1.62
40.8
18.4
28.14
25.75
mg/l
0.75
280
2389
8
33
2.46
1.54
1.0
4.2
9.72
10.76
%
—
8
33
29
186
1.61
1.54
1.4
1.9
—
—
—
0
0
23
139
1.70
1.52
7.2
8.3
0.87
0.90
%
0.09
23
128
7
27
2.62
1.52
1.3
1.4
0.86
0.23
nmol/l
—
7
20
208
1867
1.29
1.50
3.9
3.4
63.71
50.83
u/l
0.82
191
1751
11
52
2.15
1.46
1.5
1.3
—
—
—
0
0
252
2694
0.75
1.46
6.8
6.9
39.77
39.88
mmol/mol
0.07
224
2503
12
59
2.07
1.45
2.7
2.1
4.19
4.72
mmol/24h
0.24
12
51
7
29
2.44
1.40
1.1
1.1
—
—
—
0
0
16
90
1.82
1.35
1.6
1.5
291.33
292.12
ug/g
—
9
53
83
669
1.32
1.35
1.2
1.3
0.50
1.50
u/ml
1.74
15
171
8
35
2.32
1.27
1.4
2.7
3.76
2.65
nmol/l
—
8
35
6
25
2.42
1.25
1.0
1.1
—
—
—
0
0
237
2190
1.27
1.22
5.0
4.0
14.95
14.92
pmol/l
0.07
217
1956
27
183
1.52
1.17
2.1
2.5
—
14.21
—
0
14
247
2626
0.79
1.17
4.5
4.5
1.33
1.27
mmol/l
0.66
218
2388
12
65
1.88
1.15
2.6
2.9
0.76
0.97
nmol/l
—
7
54
11
58
1.93
1.13
4.5
2.7
—
—
—
0
0
176
1586
1.23
1.09
5.5
4.1
0.00
0.00
estimate
-0.00
47
340
144
1271
1.23
1.09
5.0
3.7
6.34
6.19
ph
0.89
73
718
7
33
2.14
1.06
1.3
1.1
—
11.01
—
0
8
106
909
1.24
1.04
5.9
4.4
0.00
0.01
estimate
0.50
44
313
11
186
0.58
0.99
1.5
1.4
—
—
—
0
0
243
2276
1.23
0.98
46.4
23.8
328.88
331.88
g/l
5.73
243
2268
18
116
1.58
0.98
2.6
3.6
159.50
239.80
mg/l
0.72
12
44
50
393
1.32
0.98
1.8
1.5
—
—
—
0
0
23
158
1.49
0.96
7.2
7.6
1.48
1.54
%
0.22
23
148
6
27
2.24
0.94
1.0
1.2
130.17
99.04
pmol/l
—
6
27
29
211
1.41
0.92
6.2
6.5
—
—
—
0
0
12
71
1.72
0.90
1.2
1.1
—
—
—
0
0
6
29
2.09
0.89
2.5
4.2
12.52
15.56
%
—
6
29
177
1617
1.20
0.89
5.6
4.2
0.00
0.94
estimate
0.51
44
322
114
1002
1.21
0.87
2.1
2.1
141.03
282.83
u/l
0.96
108
952
11
64
1.74
0.87
2.1
2.7
8.25
9.58
pmol/l
0.18
11
64
29
214
1.39
0.86
8.8
8.6
25.51
24.51
mmol/l
0.96
29
205
175
1602
1.19
0.85
5.5
4.2
0.00
4.60
estimate
0.50
45
353
57
470
1.26
0.79
1.3
1.3
3.16
13.44
u/ml
1.91
17
175
6
34
1.78
0.76
1.2
1.2
—
—
—
0
0
11
67
1.66
0.76
11.2
13.2
104.27
105.34
mmol/l
0.81
11
61
11
67
1.66
0.76
11.2
13.2
10.18
11.23
mmol/l
0.38
11
61
36
283
1.30
0.73
1.8
1.5
—
—
—
0
0
21
151
1.42
0.73
1.7
2.9
—
—
—
0
0
5
26
1.94
0.71
2.6
4.2
7.68
8.21
mmol/l
—
5
26
13
86
1.53
0.67
1.4
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
2.3
—
—
—
0
0
29
229
1.29
0.59
1.2
1.2
—
—
—
0
0
36
293
1.26
0.58
2.0
2.6
2.74
6.41
ug/l
3.13
31
261
8
54
1.49
0.57
1.5
4.0
18.75
29.82
u/ml
—
8
54
8
54
1.49
0.57
1.5
1.4
—
—
—
0
0
6
36
1.68
0.57
1.2
1.1
—
—
—
0
0
6
36
1.68
0.57
1.2
1.1
—
—
—
0
0
6
37
1.63
0.56
1.3
1.2
—
—
—
0
0
271
2618
1.17
0.54
6.2
5.1
2.04
1.98
mu/l
0.31
253
2374
6
97
0.61
0.53
3.0
1.9
34.50
41.86
nmol/l
—
6
92
10
145
0.68
0.51
2.3
2.0
—
—
—
0
0
12
84
1.44
0.50
4.6
2.3
121.33
127.73
g/l
—
6
63
96
871
1.14
0.49
4.2
3.6
0.00
0.10
estimate
0.58
38
271
11
76
1.46
0.48
6.5
2.8
—
—
—
0
0
43
366
1.20
0.48
1.5
1.4
—
—
—
0
0
34
285
1.21
0.44
2.7
2.7
0.32
0.58
e6/l
0.35
34
275
74
664
1.15
0.44
1.6
1.8
135937966.78
21788144.45
pmol/l
0.39
64
537
21
166
1.28
0.44
1.0
1.2
20.66
117.01
u/ml
—
5
63
113
1220
0.89
0.44
2.0
2.0
1.33
1.31
mmol/l
0.11
92
992
12
87
1.39
0.43
1.3
2.5
71.42
55.98
ug/min
—
5
48
0
15
0.00
0.41
0.0
1.0
—
2.24
—
0
5
0
15
0.00
0.41
0.0
1.7
—
0.78
—
0
8
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
3.26
—
0
10
129
1207
1.11
0.39
5.5
4.2
0.00
0.03
estimate
1.41
42
286
58
520
1.14
0.36
1.4
1.3
35.56
40.69
iu/ml
0.08
14
156
6
41
1.47
0.36
1.7
1.2
—
—
—
0
0
281
2745
1.13
0.36
5.3
5.5
5.94
6.02
mmol/l
0.53
258
2506
19
155
1.24
0.33
2.6
2.4
—
—
—
0
0
34
301
1.14
0.26
5.3
4.3
7.38
7.36
ph
0.50
27
214
9
72
1.26
0.26
1.8
1.6
261.33
272.94
mu/l
—
9
65
77
718
1.09
0.25
6.2
4.0
—
0.30
—
0
10
24
274
0.87
0.23
1.8
1.6
—
—
—
0
0
5
39
1.29
0.23
1.8
1.3
0.68
0.59
nmol/l
—
5
34
0
11
0.00
0.21
0.0
10.1
—
0.65
—
0
11
0
10
0.00
0.21
0.0
1.3
—
0.00
—
0
10
0
13
0.00
0.21
0.0
3.4
—
6.92
—
0
13
0
14
0.00
0.20
0.0
1.0
—
0.22
—
0
5
6
49
1.23
0.20
2.3
2.1
11.83
10.20
mmol/l
—
6
49
40
366
1.11
0.20
2.8
2.4
138.08
130.46
ug/g
0.04
30
282
14
162
0.86
0.16
4.6
3.7
1.01
1.02
ratio
1.60
14
154
101
1049
0.95
0.15
3.4
3.5
32.27
50.11
mg/l
1.42
67
702
7
88
0.79
0.14
1.7
1.6
—
—
—
0
0
16
181
0.88
0.14
1.4
1.2
—
—
—
0
0
86
826
1.05
0.14
3.9
3.1
—
0.09
—
0
22
26
240
1.09
0.11
12.8
3.6
4.94
5.11
kpa
0.39
26
234
73
703
1.05
0.11
5.6
4.4
1.02
1.02
kg/l
0.89
52
475
14
125
1.13
0.10
1.0
1.1
—
—
—
0
0
5
46
1.09
0.09
2.4
7.2
6.20
6.66
mmol/l
—
5
37
306
3040
1.06
0.09
53.8
27.5
4.17
4.46
e12/l
13.67
297
2973
306
3040
1.06
0.09
53.9
27.6
7.79
6.80
e9/l
1.12
296
2973
306
3040
1.06
0.09
53.9
27.5
232.97
243.32
e9/l
1.34
298
2984
6
71
0.84
0.07
1.0
1.1
—
—
—
0
0
111
1089
1.03
0.06
3.3
3.4
6.90
7.61
mmol/l
1.18
91
903
105
1070
0.97
0.06
3.9
4.2
5.00
8.38
mg/mmol
1.74
70
687
118
1160
1.03
0.06
5.7
5.9
3.81
2.34
ug/l
0.45
111
1037
21
222
0.94
0.05
1.5
1.5
—
—
—
0
0
289
2877
1.03
0.04
26.3
16.3
—
—
—
0
0
67
682
0.98
0.03
3.2
3.3
0.66
0.81
ug/l
1.11
52
458
29
299
0.97
0.02
2.7
2.3
0.00
0.04
estimate
—
6
67
17
164
1.04
0.00
16.1
3.8
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
8113.00
—
0
9
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
30.68
—
0
5
5
58
0.86
-0.00
1.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.5
—
6.65
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
19.39
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
50.13
—
0
8
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
38.00
—
0
5
0
7
0.00
-0.00
0.0
1.6
—
8.85
—
0
7
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
9
95
0.95
-0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
74.67
—
0
6
8
83
0.96
-0.00
1.0
1.1
0.88
0.90
g/l
—
8
83
8
88
0.91
-0.00
5.4
4.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
81
0.99
-0.00
1.0
1.1
1.63
1.53
g/l
—
8
81
7
78
0.90
-0.00
2.0
2.0
167.29
221.42
pmol/l
—
7
72

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_PRIMARY_LYMPHOID_HEMATOPOIETIC_NAS – Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).