retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1840 |
4. Check minimum number of eventsNone |
1840 |
5. Include endpointsNone |
1840 |
6. Filter based on genotype QC (FinnGen only) |
1673 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H35
- Name in latin
- Separatio stratorum retinae
Similar endpoints
↥List of similar endpoints to
Separation of retinal layers (serosa)
based on the number of shared cases.
Similar with more cases:
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10471 | 3365 | 7063 |
| Only index persons | 10254 | 3320 | 6934 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.10 | 0.20 |
| Only index persons | 0.22 | 0.12 | 0.26 |
| Median age at first event (years) | |||
| Whole population | 49.96 | 56.13 | 47.11 |
| Only index persons | 49.96 | 56.05 | 47.04 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1673 | 624 | 1049 |
| Unadjusted period prevalence (%) | 0.38 | 0.22 | 0.48 |
| Median age at first event (years) | 52.84 | 55.16 | 51.47 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1734
- Matched controls
- 17340
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XCK10
NOMESCO Finland
Photography of fundus of eye
9.6
311.2
422
564
XCD20
NOMESCO Finland
Photoangiography of eye
309.4
307.7
306
12
CKC12
NOMESCO Finland
Photocoagulation of retina
199.1
307.7
255
15
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
20.7
307.7
426
268
XCW99
NOMESCO Finland
Other investigative procedure of eye
14.8
307.7
578
568
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
307.7
1734
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
19.5
307.7
595
452
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
282.8
307.7
284
12
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
316.3
307.7
392
16
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
58.4
307.7
255
51
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
689.8
307.7
380
7
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.2
213.9
592
1578
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
776.3
213.5
206
*
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
130.9
124
*
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
36.4
111.7
70
20
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
936.2
91.7
89
*
ZX198
NOMESCO Finland
Other local administration
22.8
90.1
66
30
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
891.8
87.5
85
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
28.7
78.7
53
19
ZXA10
NOMESCO Finland
Bilateral
3.1
78.4
400
1520
S01BC03
ATC
diclofenac; ophthalmic
8.8
77.7
100
120
H33.0
ICD-10 Finland
Retinal detachment with retinal break
770.9
75.9
74
*
XCH00
NOMESCO Finland
Eye pressure measurement
6.1
75.2
136
238
WX140
NOMESCO Finland
Parabulbar anesthesy
9.1
75.0
94
109
H33.3
ICD-10 Finland
Retinal breaks without detachment
148.0
67.4
71
5
1LA01, ,
NOMESCO Finland
+∞
67.1
64
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
235.7
66.7
68
*
S01EC01
ATC
acetazolamide; systemic
9.5
62.5
75
82
H35.37
ICD-10 Finland
Macular holes
630.0
62.2
61
*
H35.9
ICD-10 Finland
Retinal disorder, unspecified
103.6
55.2
60
6
XCK00
NOMESCO Finland
Perimetry
4.5
54.9
139
326
H35.8
ICD-10 Finland
Other specified retinal disorders
189.2
53.2
55
*
H53.1
ICD-10 Finland
Subjective visual disturbances
3.6
51.9
186
561
H53.9
ICD-10 Finland
Visual disturbance, unspecified
4.7
51.3
123
276
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.0
47.4
228
822
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
459.4
45.5
45
*
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
220.3
42.1
43
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
6.8
40.1
63
95
1LA05, ,
NOMESCO Finland
+∞
39.7
38
*
CKD40
NOMESCO Finland
Endophotocoagulation of retina
+∞
39.7
38
*
H33.2
ICD-10 Finland
Serous retinal detachment
396.1
39.2
39
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.0
38.2
185
667
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
385.6
38.2
38
*
XCW10
NOMESCO Finland
Assessment of vision
8.5
36.9
48
58
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
364.7
36.1
36
*
H35.36
ICD-10 Finland
Macular cyst
333.2
33.0
33
*
S01BC05
ATC
ketorolac; ophthalmic
4.4
32.4
83
196
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
63.0
32.1
37
6
H34.8
ICD-10 Finland
Other retinal vascular occlusions
71.3
31.0
35
5
H33.5
ICD-10 Finland
Other retinal detachments
36.2
30.6
39
11
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.6
29.0
186
774
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
56.0
28.2
33
6
H25.1
ICD-10 Finland
Senile nuclear cataract
2.0
28.0
371
2080
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.9
28.0
422
2473
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
27.2
26
*
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
76.4
26.8
30
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
26.0
679
4683
F05
ICPC
Visual disturbance other
3.9
26.0
79
212
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
23.8
24.8
35
15
Z3231
NOMESCO Finland
Registered nurse
1.8
24.2
466
2932
H26.4
ICD-10 Finland
After-cataract
2.7
24.1
140
553
L04AA01
ATC
[U] ciclosporin
6.2
23.8
41
68
H43.1
ICD-10 Finland
Vitreous haemorrhage
7.3
23.8
35
49
S01ED51
ATC
timolol, combinations; ophthalmic
2.8
23.6
122
454
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.9
22.9
115
421
ZXA05
NOMESCO Finland
Left side
1.8
22.7
406
2491
ZX120
NOMESCO Finland
Intravenous
2.3
22.6
180
824
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
16.8
21.0
33
20
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
60.8
20.9
24
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
6.8
20.4
32
48
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
19.8
19
*
L04AX01
ATC
azathioprine; systemic
2.9
19.7
93
329
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
16.6
19.7
31
19
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
34.7
18.9
24
7
L04AA06
ATC
mycophenolic acid; systemic
4.0
18.4
53
137
H35.4
ICD-10 Finland
Peripheral retinal degeneration
44.5
18.3
22
5
ZXA00
NOMESCO Finland
Right side
1.7
17.6
422
2787
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.6
17.6
468
3177
L04AD01
ATC
ciclosporin; systemic
4.2
17.0
45
109
Z94.0
ICD-10 Finland
Kidney transplant status
5.4
16.9
33
62
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
16.7
16
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
16.7
16
*
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
4.4
16.2
40
92
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.0
15.9
175
908
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
7.0
15.3
23
33
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.1
14.4
61
203
H40.0
ICD-10 Finland
Glaucoma suspect
2.2
14.2
125
596
127
Kela drug reimbursment
Transplant complication
3.9
13.9
41
108
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.6
13.8
26
47
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
13.7
479
3436
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
5.2
13.6
28
55
Z2221
NOMESCO Finland
Medical doctor
1.6
12.8
404
2825
F29
ICPC
Eye symptom/complaint other
1.9
12.4
169
941
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
130.9
12.4
13
*
H02AB04
ATC
methylprednisolone; systemic
1.7
12.4
223
1352
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
12.3
92
410
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.5
12.2
42
123
H02AB06
ATC
prednisolone; systemic
1.4
12.2
762
6104
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.4
12.2
44
133
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.5
12.0
41
120
H20.1
ICD-10 Finland
Chronic iridocyclitis
5.7
12.0
22
39
J01MA02
ATC
ciprofloxacin; systemic
1.5
11.7
620
4806
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
11.7
178
1027
S01ED01
ATC
timolol; ophthalmic
3.1
11.6
48
158
XCH05
NOMESCO Finland
Eye pressure longterm registration
5.7
11.5
21
37
A02BC02
ATC
pantoprazole; systemic
1.4
11.5
1125
9740
C08CA01
ATC
amlodipine; oral
1.4
11.1
612
4771
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.3
11.1
22
42
H25.0
ICD-10 Finland
Senile incipient cataract
2.2
11.1
94
442
H26.2
ICD-10 Finland
Complicated cataract
5.1
11.0
23
46
H35
ICD-10 Finland
Other retinal disorders
43.6
10.9
13
*
A12AA04
ATC
calcium carbonate; oral
3.9
10.9
31
80
CA1ME
NOMESCO Finland
Ultrasound oculometry
11.3
10.5
19
17
H3601, E113,
ICD-10 Finland
+∞
10.4
10
*
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
18.9
10.3
15
8
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.9
9.9
28
72
S01EC54
ATC
brinzolamide, combinations; ophthalmic
4.6
9.8
23
51
B01AB05
ATC
enoxaparin; parenteral
1.4
9.7
465
3514
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
7.4
9.7
22
30
K85
ICPC
Elevated blood pressure
1.6
9.6
256
1713
114
Kela drug reimbursment
Glaucoma
2.0
9.5
108
566
A02BC05
ATC
esomeprazole; systemic
1.4
9.4
637
5108
H53.4
ICD-10 Finland
Visual field defects
3.1
9.4
38
124
CK2Z4
NOMESCO Finland
Ocular fundus light imaging (OCT), angiography
+∞
9.4
9
*
1LA04, ,
NOMESCO Finland
+∞
9.4
9
*
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
9.4
9
*
H3600, E113,
ICD-10 Finland
+∞
9.4
9
*
S01EE01
ATC
latanoprost; ophthalmic
2.2
9.4
79
371
C03DA01
ATC
spironolactone; oral
1.7
9.3
181
1121
Z71.8
ICD-10 Finland
Other specified counselling
1.4
9.2
507
3924
A11CC03
ATC
alfacalcidol; systemic
2.9
9.0
41
143
F43
ICPC
Eye, Other diagnostic procedure
2.9
8.9
40
139
H53.8
ICD-10 Finland
Other visual disturbances
3.5
8.8
29
83
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
4.1
8.7
23
56
N18.0
ICD-10 Finland
End-stage renal disease
4.3
8.7
22
52
L04AX03
ATC
methotrexate; systemic
1.7
8.4
155
944
V03AE01
ATC
polystyrene sulfonate; oral
3.9
8.4
24
62
ZXC15
NOMESCO Finland
Use of photodynamic technique
3.9
8.4
24
62
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.4
8.4
426
3241
J01DB01
ATC
cefalexin; oral
1.4
8.3
1363
12482
H3600, E103,
ICD-10 Finland
+∞
8.3
8
*
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
8.3
8
*
TK800
NOMESCO Finland
Hemodialysis
2.8
8.3
41
150
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.3
8.2
61
272
H02AB09
ATC
hydrocortisone; systemic
2.7
8.1
41
152
H57.1
ICD-10 Finland
Ocular pain
2.2
8.1
64
293
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
7.9
169
1071
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.6
7.9
19
29
N02BE01
ATC
paracetamol; systemic, rectal
1.5
7.8
1478
13786
S01EE04
ATC
travoprost; ophthalmic
3.3
7.7
28
86
WX002
NOMESCO Finland
Sedation and analgesia
1.5
7.6
266
1883
R51.80
ICD-10 Finland
Headache
1.5
7.6
220
1498
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
25.1
7.6
10
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
7.5
964
8424
H34.2
ICD-10 Finland
Other retinal artery occlusions
80.4
7.4
8
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
7.7
7.4
16
21
P01AB01
ATC
metronidazole; oral, rectal
1.3
7.3
566
4595
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.6
7.3
40
155
H3601, E103,
ICD-10 Finland
+∞
7.3
7
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
7.3
738
6231
SPAT1211
SPAT
Application of soft bandage
1.8
7.2
114
667
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.0
7.2
20
51
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
30.1
7.1
9
*
R01AD58
ATC
fluticasone, combinations; nasal
1.4
7.1
374
2854
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
6.1
7.1
18
30
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
7.0
517
4165
H26.02
ICD-10 Finland
Presenil cataract
2.4
7.0
44
183
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
2.4
7.0
44
183
R01AD08
ATC
fluticasone; nasal
1.4
7.0
425
3323
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.6
6.9
145
914
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
6.9
753
6406
S01EC04
ATC
brinzolamide; ophthalmic
2.3
6.8
50
222
S01EC03
ATC
dorzolamide; ophthalmic
4.1
6.8
18
44
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
6.8
344
2606
UJF32
NOMESCO Finland
Coloscopy
1.4
6.8
376
2894
CKC20
NOMESCO Finland
Cryopexy of undetached retina
40.2
6.8
8
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.8
6.8
99
566
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
16.8
6.7
10
6
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
6.7
421
3302
R01AD09
ATC
mometasone; nasal
1.3
6.7
683
5750
R06AX27
ATC
desloratadine; oral
1.4
6.7
410
3207
L17
ICPC
Foot/toe symptom/complaint
1.4
6.6
439
3472
196
Kela drug reimbursment
Paricalcitol and cinacalcet
6.4
6.6
16
25
A98
ICPC
Health maint/preventive medicine
1.9
6.6
1660
16007
M01AH05
ATC
etoricoxib; oral
1.3
6.6
1049
9367
N18.8
ICD-10 Finland
Other chronic renal failure
2.8
6.6
32
117
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
6.5
105
617
P01BA02
ATC
hydroxychloroquine; oral
1.7
6.5
110
656
205
Kela drug reimbursment
Chronic hypertension
1.4
6.5
341
2599
L04AD02
ATC
tacrolimus; systemic
3.2
6.4
24
75
A02BC03
ATC
lansoprazole; oral
1.4
6.4
415
3272
J01FF01
ATC
clindamycin; systemic
1.4
6.3
405
3183
B03XA02
ATC
darbepoetin alfa; parenteral
2.7
6.3
33
125
137
Kela drug reimbursment
Uraemia requiring dialysis
5.2
6.3
18
35
N02AX02
ATC
tramadol; systemic, rectal
1.3
6.3
686
5813
D01
ICPC
Abdominal pain/cramps general
1.6
6.3
162
1075
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
6.3
6
*
G73.7*M32.1
ICD-10 Finland
Myopathy in systemic lupus erythematosus
+∞
6.3
6
*
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
+∞
6.3
6
*
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
6.3
6
*
R05
ICPC
Cough
1.4
6.2
347
2668
S02.53
ICD-10 Finland
Fracture of tooth root
2.3
6.2
45
200
R42
ICD-10 Finland
Dizziness and giddiness
1.4
6.1
306
2311
F38
ICPC
Eye, Other laboratory test NEC
2.9
6.1
28
99
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
10.1
6.0
11
11
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
3.5
6.0
20
58
J01FA09
ATC
clarithromycin; systemic
1.3
6.0
454
3656
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1338
11708
1.63
15.65
10.6
8.4
79.10
78.40
u/l
0.20
1279
11214
32
66
4.92
14.76
29.1
29.4
105.60
132.86
ug/l
1.57
25
51
1278
11145
1.56
14.31
5.5
4.3
11.98
11.11
mm/h
1.28
1212
10512
1043
8731
1.49
14.06
11.1
10.2
4.21
4.11
e9/l
0.53
921
7623
1593
14813
1.93
12.66
19.8
15.5
23.70
24.53
mg/l
0.44
1333
12171
1269
11188
1.50
12.22
4.3
4.0
14.76
14.75
pmol/l
0.02
1191
10371
815
6619
1.44
12.10
3.8
3.0
160.19
152.54
ug/l
0.22
765
6232
897
7428
1.43
11.88
10.4
7.6
1.21
1.21
mmol/l
0.70
803
6436
1628
15296
2.05
11.86
22.8
18.2
3.99
3.99
mmol/l
0.13
1598
15026
1624
15251
2.02
11.75
22.4
18.1
139.82
139.74
mmol/l
0.62
1593
15005
821
6708
1.43
11.62
9.4
7.0
1.21
1.21
mmol/l
0.44
781
6238
1675
15936
2.50
11.46
15.4
12.0
28.94
29.05
u/l
0.09
1640
15575
1077
9254
1.43
11.41
5.2
4.3
51.00
1439.13
e6/l
1.77
11
131
1679
16027
2.50
10.75
25.2
19.8
84.56
79.20
umol/l
3.89
1663
15877
936
7898
1.40
10.65
4.6
3.6
0.01
6.67
estimate
2.06
190
1638
1476
13572
1.59
10.49
5.4
4.8
1.87
1.89
mu/l
0.43
1390
12626
350
2467
1.52
10.48
3.9
2.7
13.17
13.61
umol/l
0.58
330
2328
119
626
1.97
10.39
3.7
1.8
11.78
5.98
iu/ml
1.19
39
149
936
7930
1.39
10.21
4.6
3.6
0.05
0.21
estimate
0.36
176
1508
946
8048
1.39
9.96
7.7
7.0
11.60
11.81
umol/l
0.19
896
7738
918
7805
1.37
9.51
4.6
3.6
0.01
0.00
estimate
0.42
182
1616
787
6538
1.37
9.37
2.3
2.1
95.54
95.49
pmol/l
0.01
429
3600
640
5158
1.38
9.13
4.9
3.9
10.15
7.28
mg/mmol
0.89
425
3283
1698
16377
2.77
9.09
29.9
23.3
91.44
91.06
fl
3.23
1682
16240
1698
16380
2.76
9.03
30.0
23.3
4.56
4.59
e12/l
1.99
1666
16057
1698
16381
2.76
9.01
30.2
23.5
137.81
138.82
g/l
1.92
1682
16244
1030
8962
1.37
9.00
6.3
5.4
6.67
6.67
mmol/l
0.00
984
8575
99
514
1.98
9.00
1.7
1.5
0.59
0.28
iu/ml
0.26
18
84
1698
16383
2.76
8.97
30.0
23.4
6.73
6.67
e9/l
0.57
1666
16059
1623
15405
1.84
8.88
6.3
5.7
2.74
2.76
mmol/l
0.32
1543
14535
474
3645
1.41
8.87
2.8
2.2
2.68
2.79
mg/l
0.51
411
3123
1697
16374
2.71
8.86
30.0
23.4
246.42
246.42
e9/l
0.00
1668
16095
75
353
2.18
8.85
8.5
7.2
676.17
844.08
iu/ml
0.11
18
53
1697
16380
2.69
8.74
30.6
23.9
41.15
41.55
%
0.74
1682
16234
299
2131
1.49
8.34
4.3
2.7
23.15
23.84
%
0.40
281
2009
319
2305
1.47
8.30
4.1
2.6
2.31
2.31
g/l
0.00
303
2159
594
4787
1.37
8.28
2.4
2.2
205.77
268.56
u/l
0.41
565
4568
783
6585
1.34
8.25
2.8
2.4
76.78
76.38
nmol/l
0.15
726
6042
1605
15226
1.73
8.22
5.7
5.1
4.65
4.65
mmol/l
0.13
1522
14426
71
337
2.15
8.22
1.6
1.2
1.19
6.01
u/ml
—
8
17
658
5418
1.35
7.88
4.1
3.4
8.16
8.29
mmol/l
0.30
573
4644
1546
14561
1.57
7.78
18.0
14.9
81.48
83.01
ml/min/173m2
2.18
1453
13510
790
6694
1.33
7.74
7.3
5.3
35.95
35.99
g/l
0.07
757
6323
1597
15167
1.67
7.66
5.6
5.0
1.41
1.40
mmol/l
0.11
1509
14293
1537
14477
1.54
7.51
6.7
6.0
39.22
38.96
mmol/mol
0.65
1465
13711
54
240
2.29
7.36
1.4
1.2
3.45
5.60
u/ml
0.65
20
106
166
1069
1.61
7.29
2.3
1.6
—
—
—
0
0
594
4863
1.34
7.25
3.2
2.7
60.03
61.94
u/l
0.25
554
4549
192
1292
1.55
6.99
3.7
2.8
68.27
70.02
e9/l
0.28
147
946
263
1893
1.46
6.91
3.2
2.7
200.00
138.70
ug/g
1.05
216
1568
350
2655
1.40
6.88
3.4
3.0
0.77
0.91
e6/l
0.51
209
1395
15
21
7.20
6.70
10.1
9.2
5.14
5.31
mmol/l
0.17
15
21
807
6955
1.30
6.63
3.2
2.8
—
—
estimate
—
0
0
530
4313
1.33
6.62
3.4
2.8
351.07
351.42
umol/l
0.03
480
3886
1048
9356
1.30
6.57
3.1
2.8
—
—
—
0
0
590
4894
1.31
6.38
4.3
3.3
37.07
84.65
e6/l
1.38
456
3757
77
416
1.89
6.31
1.5
1.2
2.28
2.41
u/ml
—
9
30
77
416
1.89
6.31
1.7
1.2
5.93
10.92
u/ml
0.43
15
52
80
444
1.84
6.04
1.5
1.2
23.48
2.18
u/ml
—
6
17
782
6768
1.28
6.02
2.1
1.9
1.43
1.44
mmol/l
0.17
678
5792
203
1430
1.48
5.94
3.1
2.2
373.33
379.99
nmol/l
0.19
192
1338
427
3419
1.33
5.85
2.2
1.7
1.37
1.16
mg/l
0.35
330
2631
90
523
1.76
5.85
1.6
1.3
—
—
—
0
0
645
5463
1.29
5.84
4.6
3.5
33.08
38.44
u/l
0.85
612
5174
512
4208
1.31
5.82
4.0
3.2
0.26
0.39
e6/l
1.84
386
3079
38
163
2.36
5.68
1.4
1.4
—
—
—
0
0
242
1781
1.42
5.61
2.5
3.0
7.21
8.00
umol/l
0.43
218
1591
807
7053
1.27
5.60
17.9
13.9
1.29
1.23
inr
1.95
669
5854
30
116
2.61
5.56
1.2
1.1
—
—
—
0
0
30
116
2.61
5.56
1.2
1.1
—
—
—
0
0
31
122
2.57
5.55
1.2
1.1
—
—
—
0
0
202
1442
1.45
5.52
14.0
8.0
10.55
9.20
mmol/l
2.16
194
1388
33
135
2.47
5.47
1.2
1.2
—
—
—
0
0
51
252
2.05
5.42
1.4
1.2
3.65
3.37
u/ml
0.07
20
90
1531
14574
1.43
5.40
5.6
5.0
5.92
5.95
mmol/l
0.36
1431
13581
29
112
2.62
5.40
1.2
1.1
—
—
—
0
0
179
1257
1.47
5.33
2.8
2.9
10.48
10.63
g/l
0.19
163
1169
1525
14516
1.42
5.29
4.8
4.3
1.39
1.37
mmol/l
0.59
1428
13591
698
6026
1.26
5.26
4.4
3.5
0.03
0.04
estimate
0.26
155
1345
481
3966
1.29
5.25
5.2
4.4
90.07
89.75
%
0.10
470
3889
154
1054
1.51
5.20
7.0
4.0
127.34
86.39
ng/l
2.38
141
935
108
683
1.62
5.16
2.3
1.8
1.49
1.58
g/l
0.44
98
591
412
3351
1.30
4.95
3.6
2.6
4.23
4.79
e6/l
0.38
375
3085
85
511
1.70
4.94
4.3
2.1
95.15
93.08
%
0.34
79
496
74
429
1.76
4.90
1.5
1.4
—
—
—
0
0
28
112
2.52
4.88
1.3
1.1
—
—
—
0
0
513
4300
1.27
4.86
5.0
3.8
0.00
0.01
estimate
1.34
172
1493
176
1257
1.45
4.81
2.9
2.9
66.65
66.96
g/l
0.22
162
1175
58
317
1.86
4.66
1.7
1.7
—
—
—
0
0
43
212
2.05
4.64
1.3
1.1
6.40
15.70
u/ml
—
5
10
246
1875
1.36
4.61
1.9
1.8
—
—
—
0
0
489
4100
1.27
4.58
1.9
1.7
20.02
19.96
nmol/l
0.03
428
3525
49
255
1.95
4.57
1.2
1.1
—
—
—
0
0
204
1511
1.40
4.56
6.9
3.8
1.36
2.06
mmol/l
2.28
178
1305
362
2924
1.30
4.55
1.6
1.5
2.51
2.56
g/l
0.20
232
1870
75
447
1.71
4.53
1.4
1.4
—
—
—
0
0
522
4417
1.26
4.51
3.1
3.1
1043.80
1080.36
ng/l
0.11
443
3730
307
2428
1.32
4.49
3.6
3.1
1.63
1.72
e6/l
0.07
159
1165
77
464
1.69
4.47
5.1
2.4
191.51
190.50
%
0.03
72
438
78
472
1.68
4.46
1.5
1.4
7.06
7.08
u/l
0.01
65
382
442
3676
1.27
4.40
3.0
2.5
—
—
—
0
0
309
2463
1.31
4.27
2.1
2.0
—
—
—
0
0
147
1039
1.45
4.26
2.5
2.5
17.09
20.99
au/ml
0.30
15
114
103
676
1.56
4.26
2.1
1.5
14.86
20.43
iu/ml
—
5
23
55
305
1.83
4.25
2.2
1.4
147.68
159.62
au/ml
0.29
18
82
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
78
481
1.65
4.17
6.0
2.8
0.36
0.34
iu/ml
0.11
45
252
40
201
2.01
4.14
1.3
1.4
239.59
344.85
pmol/l
1.61
34
179
144
1021
1.45
4.11
1.3
1.3
198.77
239.03
u/ml
0.33
134
941
206
1555
1.37
4.11
6.8
3.7
5.78
5.86
kpa
0.65
200
1511
1181
10975
1.24
4.11
4.0
3.4
61.97
52.66
u/l
1.36
1126
10452
322
2599
1.29
4.04
1.4
1.3
9.08
10.76
u/ml
0.20
143
1037
390
3228
1.27
4.00
1.3
1.3
1.49
1.83
u/ml
0.19
109
917
1332
12563
1.26
3.96
23.5
19.1
13.65
13.57
%
1.60
1316
12401
45
240
1.90
3.94
1.2
1.2
113.30
114.62
%
0.10
40
223
305
2454
1.29
3.92
1.6
1.5
—
—
—
0
0
56
322
1.76
3.87
1.6
1.2
278.12
265.26
u/ml
0.13
46
199
576
4999
1.23
3.85
4.1
3.5
2.35
2.35
mmol/l
0.82
529
4588
19
71
2.69
3.83
1.3
1.1
—
—
—
0
0
22
89
2.49
3.80
1.4
1.4
—
—
—
0
0
302
2437
1.29
3.79
3.7
2.1
29.15
29.59
s
0.71
295
2377
776
6948
1.21
3.77
5.3
4.8
2.17
2.10
ug/l
0.22
715
6390
162
1194
1.39
3.75
1.6
1.4
—
—
—
0
0
663
5850
1.22
3.73
3.8
3.6
44.85
64.45
ng/l
0.60
481
4074
19
72
2.66
3.73
1.8
1.5
1.74
1.75
u/field
0.01
14
53
228
1776
1.33
3.70
5.9
4.7
241.30
246.44
u/l
0.23
221
1690
259
2055
1.31
3.69
13.2
6.3
1.07
1.02
mmol/l
1.53
247
1906
1358
12870
1.25
3.68
24.9
19.5
332.94
333.70
g/l
2.55
1353
12808
169
1264
1.37
3.59
2.9
2.7
66.45
69.56
ml/min/173m2
0.38
67
515
341
2819
1.26
3.51
1.4
1.3
28.64
30.53
iu/ml
0.13
115
871
21
87
2.43
3.47
2.4
3.0
949.81
852.51
u/ml
0.10
21
87
261
2090
1.29
3.47
2.7
2.4
13.73
14.07
nmol/l
0.32
248
1939
634
5601
1.21
3.46
4.2
4.0
22.13
21.35
%
0.74
316
2468
83
547
1.54
3.42
5.6
3.6
24.35
25.01
mmol/l
1.24
78
506
32
160
2.02
3.40
1.6
1.3
32479.24
96873.42
e6/l
0.72
21
107
7
10
7.02
3.36
1.6
1.3
—
—
—
0
0
69
439
1.60
3.32
1.6
1.7
—
—
—
0
0
70
449
1.58
3.26
1.6
1.2
—
—
—
0
0
79
523
1.53
3.21
4.5
3.0
1.63
1.46
mg/l
0.89
72
485
71
459
1.57
3.20
1.5
1.5
260.56
280.05
ug/g
0.36
45
267
224
1777
1.30
3.20
2.0
1.9
—
—
—
0
0
133
977
1.39
3.17
5.2
3.2
131.45
131.65
g/l
0.03
128
954
35
186
1.90
3.16
1.1
1.2
—
—
—
0
0
65
413
1.60
3.16
1.8
1.6
22108.44
13850.30
e6/l
0.57
45
294
192
1498
1.32
3.10
2.5
2.6
40.70
77.95
u/l
0.61
172
1302
51
309
1.67
3.00
1.1
1.1
3.87
1.62
u/ml
0.35
32
168
410
3518
1.22
2.96
4.9
3.7
1.02
1.45
kg/l
0.50
287
2344
319
2671
1.24
2.91
4.8
3.7
0.83
0.82
mmol/l
0.51
305
2540
63
407
1.57
2.88
3.5
3.2
2.46
1.96
index
0.29
35
226
33
178
1.87
2.87
2.7
2.4
20.76
47.77
iu/ml
—
5
22
20
89
2.26
2.87
1.5
1.4
—
—
—
0
0
6
9
6.68
2.87
4.8
7.3
—
—
—
0
0
168
1305
1.32
2.82
5.5
3.0
5.13
4.65
kpa
1.13
162
1268
10
28
3.59
2.78
1.1
1.1
—
—
—
0
0
274
2268
1.25
2.78
1.9
1.7
1142.77
1170.71
nmol/l
0.17
219
1733
21
97
2.18
2.77
1.0
1.1
1.00
1.11
u/l
—
10
49
214
1728
1.27
2.68
7.7
6.4
—
—
—
0
0
76
521
1.48
2.67
1.6
1.8
—
—
—
0
0
82
571
1.46
2.66
1.3
1.4
28.55
26.91
iu/l
0.14
64
481
487
4285
1.19
2.66
3.1
3.0
0.72
0.72
ug/l
0.04
322
2578
43
258
1.68
2.65
1.1
1.1
0.50
1.61
u/ml
2.19
21
124
59
384
1.56
2.64
1.2
1.1
—
—
—
0
0
16
67
2.40
2.63
1.3
1.1
—
—
—
0
0
16
68
2.37
2.56
1.5
1.4
—
—
—
0
0
16
68
2.37
2.56
1.5
1.4
—
—
—
0
0
13
50
2.61
2.53
1.3
1.3
—
—
—
0
0
112
833
1.37
2.53
2.0
2.0
36.53
38.37
nmol/l
0.60
112
808
490
4332
1.18
2.52
3.8
3.1
0.01
0.04
estimate
0.49
149
1279
160
1256
1.30
2.51
3.5
2.3
0.52
0.44
e6/l
0.16
153
1194
58
383
1.53
2.45
1.2
1.1
—
—
—
0
0
98
717
1.39
2.45
2.3
2.1
40.35
39.39
u/l
0.16
91
648
22
110
2.01
2.41
1.0
1.1
—
—
—
0
0
22
110
2.01
2.41
1.3
1.2
—
—
—
0
0
22
111
1.99
2.36
1.3
1.2
—
—
—
0
0
31
176
1.78
2.35
1.6
1.5
57.14
61.20
%
0.26
22
109
114
862
1.35
2.33
5.2
3.4
0.58
1.84
mmol/l
2.79
84
640
18
85
2.13
2.29
1.1
1.2
—
—
—
0
0
10
35
2.87
2.21
1.7
1.5
—
—
—
0
0
29
165
1.77
2.19
1.9
1.6
—
—
—
0
0
29
165
1.77
2.19
1.9
1.6
—
—
—
0
0
15
67
2.25
2.18
2.1
2.5
—
—
—
0
0
30
173
1.75
2.17
1.8
1.5
—
—
—
0
0
29
166
1.76
2.16
1.9
1.6
—
—
—
0
0
71
504
1.43
2.14
2.5
3.8
35.13
61.95
mg/l
0.60
62
425
71
505
1.42
2.12
2.5
3.8
50.33
61.11
mg/l
0.35
62
426
36
221
1.64
2.10
1.1
1.1
2.26
3.90
u/ml
0.66
18
94
28
161
1.75
2.06
1.3
1.3
26.19
25.28
u/l
0.05
23
124
42
270
1.57
2.04
1.1
1.1
5.00
4.81
u/ml
0.03
27
139
29
170
1.72
2.01
1.9
1.5
—
—
—
0
0
54
370
1.47
1.97
1.1
1.3
1390.15
1486.74
e6/l
0.02
39
281
27
156
1.74
1.97
1.3
1.4
—
—
—
0
0
7
21
3.34
1.96
1.0
1.0
4.36
6.97
u/ml
—
7
21
14
64
2.20
1.94
1.6
2.2
—
—
—
0
0
14
64
2.20
1.94
1.6
2.2
—
—
—
0
0
5
11
4.56
1.94
1.0
2.1
—
—
—
0
0
139
1112
1.27
1.93
3.3
2.9
197.93
177.17
ng/l
0.20
123
1024
89
670
1.35
1.92
1.9
2.0
215.10
211.45
pmol/l
0.13
83
640
90
679
1.34
1.92
1.1
1.0
—
—
—
0
0
53
365
1.47
1.90
1.2
1.3
262.68
55.24
e6/l
0.37
34
267
29
173
1.69
1.90
1.9
1.5
—
—
—
0
0
213
1794
1.21
1.86
5.5
4.7
31.38
31.07
%
0.16
160
1210
54
375
1.45
1.86
1.1
1.2
3.72
3.74
mmol/l
0.06
49
352
52
359
1.46
1.85
1.4
1.7
—
—
—
0
0
40
262
1.54
1.82
1.1
1.1
1.16
1.76
u/ml
0.28
19
106
46
311
1.49
1.81
1.5
1.5
—
—
—
0
0
8
29
2.77
1.79
1.0
1.1
—
—
—
0
0
13
60
2.18
1.78
1.5
1.1
—
—
—
0
0
14
67
2.10
1.76
2.8
2.6
0.62
0.61
mmol/l
0.31
14
67
182
1519
1.22
1.75
2.6
2.3
0.23
0.22
g/l
0.59
175
1422
25
147
1.71
1.74
1.5
1.4
22.14
30.18
%
0.76
16
91
114
903
1.28
1.74
1.2
1.2
111.49
140.15
u/ml
0.45
37
349
7
24
2.92
1.72
1.1
1.2
—
—
—
0
0
5
13
3.85
1.71
1.0
1.2
—
—
—
0
0
87
666
1.32
1.71
4.1
3.2
25.30
25.44
mmol/l
0.17
82
642
17
90
1.90
1.65
1.2
1.2
0.52
0.54
ratio
—
10
56
19
105
1.82
1.63
2.2
2.0
0.45
1.39
u/field
1.17
11
61
71
532
1.35
1.62
1.7
1.7
7.26
16.33
u/ml
2.35
17
133
75
567
1.34
1.62
2.3
2.5
2.89
2.94
g/l
0.21
68
526
10
42
2.39
1.61
2.4
1.6
1217.92
118.21
nmol/24h
—
10
42
38
254
1.51
1.61
1.4
1.6
—
—
—
0
0
317
2809
1.16
1.55
3.2
3.0
2.44
2.45
mmol/l
0.38
294
2548
265
2319
1.17
1.53
1.8
1.9
1.50
1.49
%
0.06
235
2063
35
233
1.51
1.52
1.1
1.1
2.06
2.44
u/ml
0.14
21
110
5
15
3.34
1.52
1.2
1.0
—
—
—
0
0
5
15
3.34
1.52
1.2
1.2
—
—
—
0
0
6
21
2.86
1.50
1.3
1.2
—
—
—
0
0
78
601
1.31
1.49
2.3
2.5
7.25
7.32
g/l
0.12
71
560
78
601
1.31
1.49
2.3
2.5
4.27
4.23
g/l
0.14
71
560
78
601
1.31
1.49
2.3
2.5
3.87
3.72
g/l
0.36
71
560
70
531
1.33
1.49
2.4
2.6
10.61
10.47
g/l
0.10
63
486
5
16
3.13
1.44
1.2
1.1
—
—
—
0
0
5
16
3.13
1.44
1.8
1.5
—
—
—
0
0
12
59
2.04
1.43
1.0
1.1
—
—
—
0
0
6
22
2.73
1.43
1.2
1.2
—
—
—
0
0
52
380
1.38
1.42
1.8
1.9
2.41
4.16
iu/l
2.30
18
147
15
81
1.86
1.40
1.5
1.4
12.65
23.71
umol/l
2.61
15
74
32
215
1.50
1.36
1.3
1.5
0.61
0.64
nmol/l
0.23
32
208
14
75
1.87
1.34
1.0
1.1
—
—
—
0
0
10
47
2.13
1.33
1.1
1.1
—
—
—
0
0
16
90
1.79
1.33
1.1
1.1
—
—
—
0
0
60
455
1.33
1.31
2.7
3.7
1.68
3.33
ratio
0.90
33
254
75
588
1.29
1.30
1.5
1.2
0.76
0.87
u/ml
—
9
41
25
162
1.55
1.26
1.4
2.3
37.00
19.75
mg/l
—
10
64
333
3009
1.13
1.24
1.9
1.7
421.09
34759153.12
pmol/l
3.06
280
2549
57
434
1.32
1.23
1.5
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
15
85
1.77
1.23
1.1
1.1
—
—
—
0
0
89
719
1.25
1.22
6.9
5.2
1.74
1.66
%
0.30
84
683
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
8
37
2.17
1.21
1.8
1.2
—
—
—
0
0
86
693
1.25
1.21
1.1
1.1
—
0.80
—
0
8
21
132
1.60
1.20
4.0
3.6
13.23
12.65
index
0.10
13
86
40
289
1.39
1.20
1.3
1.3
—
—
—
0
0
40
289
1.39
1.20
1.3
1.3
—
—
—
0
0
6
26
2.31
1.18
1.3
1.1
5.43
0.55
u/ml
—
6
16
329
2983
1.13
1.17
4.3
3.9
227.64
526.38
ng/l
0.95
267
2337
6
128
0.47
1.16
2.7
1.8
—
—
—
0
0
157
1354
1.18
1.13
1.8
1.9
—
—
—
0
0
25
167
1.50
1.12
1.0
1.1
—
—
—
0
0
80
646
1.25
1.12
1.3
1.4
—
—
—
0
0
49
371
1.33
1.12
3.6
3.0
8.52
7.98
kpa
1.73
49
364
20
127
1.58
1.11
2.7
2.2
19.59
18.97
nmol/l
0.10
20
116
19
120
1.59
1.08
1.2
1.1
95.95
107.76
pmol/l
0.45
19
120
26
177
1.48
1.08
2.0
1.4
276.57
279.69
mosm/kgh2o
0.26
21
131
37
273
1.36
1.01
6.6
3.6
12.33
8.81
pmol/l
0.91
37
273
28
197
1.43
1.00
1.1
1.1
0.50
0.29
u/ml
—
6
65
31
425
0.72
1.00
1.4
1.3
156.73
220.02
miu/ml
0.50
11
180
98
821
1.21
1.00
1.8
1.8
0.35
0.34
mg/l
0.05
62
437
151
1319
1.16
0.95
2.2
2.3
7.66
8.38
ug/l
0.18
129
1200
41
311
1.33
0.95
1.5
1.7
—
—
—
0
0
142
1235
1.16
0.95
1.7
1.9
—
—
—
0
0
23
158
1.46
0.93
1.3
1.1
—
—
—
0
0
9
52
1.73
0.92
4.9
2.8
—
—
—
0
0
6
28
2.15
0.91
1.5
1.8
—
—
—
0
0
213
1913
1.13
0.91
9.0
9.0
0.73
1.01
mmol/l
0.60
185
1594
172
1528
1.14
0.87
3.5
3.4
—
—
—
0
0
8
43
1.86
0.87
1.0
1.0
84.31
56.57
u/ml
—
8
43
29
212
1.37
0.86
1.3
1.1
—
—
—
0
0
65
532
1.23
0.86
2.5
2.7
0.46
1.14
g/l
1.50
57
473
8
44
1.82
0.86
1.4
1.1
—
—
—
0
0
24
170
1.42
0.85
3.0
2.0
—
—
—
0
0
68
560
1.22
0.85
1.8
2.2
—
—
—
0
0
15
227
0.66
0.84
1.2
1.1
—
—
—
0
0
66
543
1.22
0.83
2.3
2.8
—
—
—
0
0
6
112
0.53
0.83
2.0
1.6
—
—
—
0
0
56
453
1.24
0.83
2.3
2.6
0.00
0.00
g/l
-0.00
51
404
44
346
1.28
0.82
1.8
1.7
—
—
—
0
0
6
32
1.88
0.82
1.0
1.3
—
—
—
0
0
125
1093
1.15
0.81
10.2
11.7
0.61
0.64
%
0.52
125
1086
8
47
1.71
0.80
1.1
1.1
—
—
—
0
0
17
246
0.69
0.78
2.4
1.9
1.40
1.65
mmol/l
0.71
17
239
22
157
1.41
0.76
3.1
2.1
—
—
—
0
0
21
149
1.41
0.75
5.1
2.5
—
—
—
0
0
9
53
1.70
0.75
1.1
1.4
4.11
4.95
umol/l
—
9
45
49
396
1.24
0.75
1.2
1.1
3.38
3.33
—
5
65
67
560
1.20
0.75
3.8
2.8
23.70
24.81
mmol/l
1.90
67
553
127
1120
1.14
0.74
9.7
11.4
1.32
1.33
%
0.05
127
1114
5
24
2.09
0.74
3.4
1.3
1.20
1.19
mmol/l
—
5
24
5
24
2.09
0.74
1.6
2.4
—
—
—
0
0
39
307
1.28
0.74
2.3
2.2
290.11
122.78
ug/min
0.35
24
183
171
1541
1.12
0.72
1.6
1.5
—
—
—
0
0
17
117
1.46
0.71
7.5
6.3
63.61
52.07
u/ml
—
9
39
34
264
1.29
0.71
1.2
1.1
19.03
18.31
au/ml
—
9
82
19
134
1.42
0.71
1.0
1.3
3.79
0.85
u/ml
—
10
71
7
40
1.75
0.71
1.0
1.1
—
—
—
0
0
7
40
1.75
0.71
1.0
1.1
—
—
—
0
0
127
1126
1.14
0.70
10.1
11.5
94.70
93.91
%
1.84
127
1121
7
41
1.71
0.70
1.3
1.1
—
—
—
0
0
7
43
1.63
0.67
1.3
1.1
—
—
—
0
0
50
413
1.22
0.65
2.1
1.9
—
—
—
0
0
26
198
1.32
0.64
1.5
1.4
173.17
210.85
pmol/l
0.36
26
198
12
177
0.68
0.63
1.4
1.2
1.58
1.54
nmol/l
0.07
12
163
11
71
1.55
0.62
1.3
1.5
—
—
—
0
0
102
902
1.14
0.60
1.8
1.6
—
—
—
0
0
9
138
0.65
0.60
1.3
1.3
167.11
430.26
u/l
—
9
132
8
51
1.57
0.60
5.4
2.8
—
—
—
0
0
8
51
1.57
0.60
5.4
2.8
—
—
—
0
0
12
80
1.50
0.59
8.6
8.0
2.64
398.19
ug/l
—
7
56
8
53
1.51
0.58
3.8
1.4
9.13
8.79
ug/l
—
8
53
60
701
0.85
0.58
1.1
1.1
0.70
0.68
ratio
—
5
88
46
383
1.21
0.57
1.4
1.2
—
—
—
0
0
6
36
1.67
0.56
5.0
2.6
2.50
5.00
ug/l
—
6
36
10
65
1.54
0.55
1.1
1.3
125.10
179.84
mmol/24h
—
10
65
87
768
1.14
0.54
1.6
1.4
—
—
—
0
0
43
358
1.21
0.54
1.4
1.5
—
—
—
0
0
9
60
1.50
0.54
1.0
1.0
—
—
—
0
0
18
134
1.35
0.53
3.2
1.9
—
—
—
0
0
18
134
1.35
0.53
3.2
1.9
—
—
—
0
0
18
134
1.35
0.53
3.2
1.9
—
—
—
0
0
16
117
1.37
0.52
1.1
1.0
223.10
263.89
ng/l
—
10
80
16
117
1.37
0.52
1.1
1.0
34.63
36.73
ng/l
—
8
77
16
117
1.37
0.52
1.1
1.0
755.50
759.92
ng/l
—
8
77
168
1546
1.10
0.52
3.9
4.5
7.21
16.20
ug/l
1.41
134
1262
13
92
1.42
0.50
2.4
1.5
—
—
—
0
0
6
41
1.46
0.50
1.2
1.2
—
—
—
0
0
68
596
1.15
0.49
3.5
2.4
220.73
455.57
ug/l
1.55
62
567
26
208
1.25
0.48
1.1
1.1
4.21
2.27
eliau/ml
0.43
11
98
55
476
1.16
0.47
1.7
2.1
—
—
—
0
0
21
164
1.28
0.46
1.1
1.4
—
—
—
0
0
65
738
0.88
0.46
1.1
1.2
1.47
1.48
g/l
0.18
65
738
43
366
1.18
0.45
1.2
1.1
3.32
5.47
eliau/ml
—
6
50
49
425
1.16
0.42
2.3
1.9
—
—
—
0
0
27
327
0.82
0.42
3.0
2.6
17.67
16.42
%
1.52
27
320
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.2
—
—
—
0
0
19
151
1.26
0.38
1.2
1.1
268.79
275.41
mg/l
0.18
19
138
11
80
1.38
0.38
1.9
1.8
—
—
—
0
0
27
224
1.21
0.38
1.4
1.5
704.38
1043.67
mu/l
1.59
21
178
41
354
1.16
0.38
2.8
2.3
139.55
130.26
g/l
1.74
33
271
9
69
1.31
0.37
4.9
2.4
—
—
—
0
0
9
69
1.31
0.37
4.9
2.4
—
—
—
0
0
9
69
1.31
0.37
4.9
2.4
—
—
—
0
0
9
69
1.31
0.37
4.9
2.4
—
—
—
0
0
9
70
1.29
0.36
1.2
1.5
81.20
52.17
ug/l
—
9
70
6
43
1.40
0.35
16.7
6.6
6.10
5.44
kpa
—
6
43
10
73
1.37
0.34
2.5
3.5
1.40
1.29
%
—
10
73
6
45
1.33
0.33
1.3
1.3
—
—
—
0
0
14
109
1.29
0.33
1.6
2.1
—
—
—
0
0
20
242
0.82
0.33
3.7
3.1
6.74
116.92
u/ml
0.93
20
236
23
192
1.20
0.32
2.0
2.2
31.83
32.64
pg
0.36
23
192
58
522
1.11
0.32
2.6
2.0
—
—
—
0
0
39
342
1.14
0.31
1.6
1.5
—
—
—
0
0
11
84
1.31
0.30
2.0
1.9
117.54
103.78
ng/l
0.13
11
84
7
55
1.27
0.30
1.0
1.8
40.96
41.91
g/l
—
7
55
30
259
1.16
0.30
1.4
1.5
—
—
—
0
0
7
56
1.25
0.29
1.0
1.1
—
—
—
0
0
31
270
1.15
0.28
1.2
1.1
1.55
1.47
g/l
0.50
31
245
10
76
1.32
0.28
2.6
1.9
13.15
1.51
nmol/l
—
10
66
22
187
1.18
0.26
1.4
1.2
8.68
7.38
mmol/l
0.44
16
165
5
74
0.67
0.26
1.8
4.3
—
—
—
0
0
6
82
0.73
0.24
1.0
4.6
—
—
—
0
0
25
286
0.87
0.24
3.4
3.4
35.21
27.51
mg/l
0.40
19
190
26
227
1.15
0.24
1.5
1.3
—
—
—
0
0
205
1970
1.05
0.23
2.1
2.1
3.81
3.68
ratio
0.31
162
1595
52
477
1.09
0.22
1.9
1.8
—
—
—
0
0
14
116
1.21
0.22
1.3
1.2
—
—
—
0
0
17
144
1.18
0.22
1.6
2.0
—
—
—
0
0
13
107
1.22
0.21
1.5
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
4.9
—
—
—
0
0
10
80
1.25
0.20
1.6
1.1
1454.20
1497.96
miu/ml
—
10
80
70
657
1.07
0.18
3.5
3.2
1.02
1.02
ratio
1.76
64
609
7
58
1.21
0.18
1.1
3.0
1.11
0.99
ug/l
—
7
53
8
71
1.13
0.16
1.1
1.1
102.18
199.36
iu/ml
—
8
71
31
283
1.10
0.16
2.8
2.0
—
—
—
0
0
20
224
0.89
0.15
1.7
1.8
—
—
—
0
0
17
150
1.13
0.14
1.5
1.6
249.24
322.37
mu/l
1.42
17
121
8
98
0.82
0.13
1.9
1.7
—
—
—
0
0
9
107
0.84
0.13
1.9
1.7
—
—
—
0
0
58
551
1.05
0.12
3.8
4.1
1.37
1.34
mmol/l
0.08
58
542
13
114
1.14
0.11
1.2
1.4
88.31
82.26
umol/l
0.74
13
114
24
259
0.93
0.10
2.5
2.3
10352.00
2344.40
u/l
—
8
88
18
164
1.10
0.09
4.4
4.4
—
—
—
0
0
6
56
1.07
0.08
1.8
1.9
95.87
57.38
ug/l
—
6
56
33
349
0.94
0.08
1.4
1.6
—
—
—
0
0
15
137
1.10
0.07
1.3
1.5
—
—
—
0
0
8
77
1.04
0.07
1.0
1.1
—
—
—
0
0
141
1438
0.98
0.07
1.9
1.8
3.35
3.53
mmol/l
1.02
97
1045
10
89
1.12
0.07
1.8
1.7
—
—
—
0
0
8
94
0.85
0.06
1.5
1.5
—
1753841.50
—
0
6
8
95
0.84
0.06
1.9
1.7
—
—
—
0
0
22
234
0.94
0.06
1.1
1.0
—
—
—
0
0
15
138
1.09
0.06
1.3
1.5
0.76
1.20
ratio
—
10
85
15
138
1.09
0.06
1.3
1.5
0.94
0.95
ratio
—
10
85
15
138
1.09
0.06
1.3
1.5
0.84
1.22
ratio
—
10
85
60
582
1.03
0.06
1.5
1.9
3.87
5.14
mg/l
0.43
42
435
10
111
0.90
0.06
1.6
1.2
—
—
—
0
0
116
1141
1.02
0.05
4.7
4.3
1.22
1.23
mmol/l
0.23
103
1008
15
140
1.07
0.04
1.3
1.4
24865.00
65753.60
e6/l
—
8
77
20
210
0.95
0.03
1.5
1.9
—
—
—
0
0
25
260
0.96
0.03
4.2
3.1
0.73
0.76
nmol/l
0.13
19
209
15
142
1.06
0.02
1.2
1.5
—
—
—
0
0
11
103
1.07
0.02
1.0
1.2
—
—
—
0
0
16
167
0.96
0.01
1.3
1.4
14582.50
1949.15
e6/l
—
10
114
11
105
1.05
0.00
1.5
1.9
—
—
—
0
0
10
99
1.01
0.00
1.2
1.4
12.10
12.91
u/l
—
10
93
15
154
0.97
0.00
1.4
1.5
—
—
—
0
0
35
353
0.99
0.00
1.5
1.4
0.92
0.92
nmol/l
0.00
28
306
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
10.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.2
1.9
—
—
—
0
0
5
52
0.96
-0.00
1.8
2.7
10.02
10.19
kpa
—
5
52
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
7.89
—
0
6
5
52
0.96
-0.00
1.8
2.7
4.70
4.80
kpa
—
5
52
0
5
0.00
-0.00
0.0
1.0
—
1745.20
—
0
5
8
89
0.90
-0.00
1.8
1.2
9.25
8.65
mm/h
—
8
89
Mortality – FinRegistry
↥Association
Association between endpoint H7_RETINASEPAR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINASEPAR | 0.841 [0.72, 0.98] | 0.026 |
| Birth year | 0.995 [0.99, 1.0] | 0.238 |
During the follow-up period (1.1.1998 — 31.12.2019), 301 out of 3022 females with H7_RETINASEPAR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETINASEPAR | 0.78 [0.68, 0.89] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 454 out of 6289 males with H7_RETINASEPAR died.
Mortality risk
Mortality risk for people of age
years, who have H7_RETINASEPAR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.074% | 0.139% |
| 5 | 0.577% | 0.861% |
| 10 | 1.373% | 2.266% |
| 15 | 2.356% | 4.337% |
| 20 | 4.263% | 7.317% |
Relationships between endpoints
↥Index endpoint: H7_RETINASEPAR – Separation of retinal layers (serosa)
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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