Lagophthalmos

H7_LAGOPHTALMOS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H02.2
  • Hospital discharge: ICD-9 3742
  • Hospital discharge: ICD-8 37813
  • Cause of death: ICD-10 H02.2
  • Cause of death: ICD-9 3742
  • Cause of death: ICD-8 37813

2 out of 7 registries used, show all original rules.

519

4. Check minimum number of events

None

519

5. Include endpoints

None

519

6. Filter based on genotype QC (FinnGen only)

463

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H02
Name in latin
Lagophthalmus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3022 1641 1356
Only index persons 2486 1397 1089
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.04
Only index persons 0.05 0.05 0.04
Median age at first event (years)
Whole population 65.73 66.16 65.28
Only index persons 65.12 65.30 64.89

-FinnGen-

Key figures

All Female Male
Number of individuals 463 259 204
Unadjusted period prevalence (%) 0.09 0.09 0.09
Median age at first event (years) 66.40 64.63 68.65

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
481
Matched controls
4810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G51.0
ICD-10 Finland
Bell palsy
81.3
307.7
192
39
H02.2
ICD-10 Finland
Lagophthalmos
+∞
307.7
465
*
H02.3
ICD-10 Finland
Blepharochalasis
118.9
201.5
103
11
H04.10
ICD-10 Finland
Dry eye syndrome
14.8
140.3
144
135
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
12.4
119.4
409
1508
H02.1
ICD-10 Finland
Ectropion of eyelid
1436.3
119.1
111
*
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
+∞
113.1
104
*
H16.0
ICD-10 Finland
Corneal ulcer
12.5
92.3
100
99
CBH25
NOMESCO Finland
Tarsorrhaphy
+∞
87.2
81
*
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
+∞
86.1
80
*
D33.30
ICD-10 Finland
Acoustic neuroma
48.4
81.3
48
11
CBN30
NOMESCO Finland
Shortening of canthal ligament
+∞
78.3
73
*
H02.4
ICD-10 Finland
Ptosis of eyelid
116.7
65.9
70
7
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
43.4
41
*
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
432.0
40.7
40
*
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
+∞
39.1
37
*
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
396.5
37.6
37
*
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
384.8
36.5
36
*
WX002
NOMESCO Finland
Sedation and analgesia
3.6
36.1
164
606
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.3
32.9
100
278
CBH30
NOMESCO Finland
Tarsorraphy
+∞
30.5
29
*
QAJ10
NOMESCO Finland
Browlift
+∞
30.5
29
*
Z3229
NOMESCO Finland
Other healthcare associate professional
4.6
29.7
80
202
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.4
29.4
84
222
ZZC00
NOMESCO Finland
Graft of fascia
309.8
29.1
29
*
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
4.9
28.9
70
162
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
+∞
28.4
27
*
CBD99
NOMESCO Finland
Other plastic reconstruction of eyelid
+∞
27.3
26
*
CBF99
NOMESCO Finland
Other operation for ectropion
+∞
27.3
26
*
XCK10
NOMESCO Finland
Photography of fundus of eye
4.0
27.3
90
264
F29
ICPC
Eye symptom/complaint other
4.0
27.0
89
261
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
63.8
26.3
30
5
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
7.5
26.3
39
56
ZXA05
NOMESCO Finland
Left side
2.8
24.5
178
836
WX110
NOMESCO Finland
Infiltration anesthesia
3.2
24.1
381
2632
TQW40
NOMESCO Finland
Remowal of suture of skin
4.1
23.5
70
190
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.0
23.4
130
526
ZXA10
NOMESCO Finland
Bilateral
2.9
22.1
136
580
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
30.7
22.1
29
10
CBH10
NOMESCO Finland
Plactic repair of canthus
+∞
22.0
21
*
QAJ20
NOMESCO Finland
Subperiosteal facelift
+∞
21.0
20
*
QAJ30
NOMESCO Finland
Other facelift
80.5
20.9
23
*
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
115.0
20.7
22
*
9560/0-C72.4
ICD-O-3
Schwannoma, NOS, of acoustic nerve
50.4
20.3
24
5
ZXD10
NOMESCO Finland
Scheduled procedure
2.4
20.1
224
1266
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
30.4
19.8
26
9
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
109.6
19.7
21
*
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
208.2
19.7
20
*
E85.80
ICD-10 Finland
Meretoja sick
208.2
19.7
20
*
H57.1
ICD-10 Finland
Ocular pain
6.0
19.3
35
62
H01.0
ICD-10 Finland
Blepharitis
5.0
19.1
43
93
S18
ICPC
Laceration/cut
2.4
18.9
279
1769
ELB50
NOMESCO Finland
Total parotidectomy
104.2
18.7
20
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
38.3
17.8
22
6
CBB30
NOMESCO Finland
Excision of lesion of eyelid
6.2
17.7
31
53
H16.9
ICD-10 Finland
Keratitis, unspecified
13.3
17.4
30
24
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.1
17.3
80
288
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.7
17.0
58
172
CBN50
NOMESCO Finland
Excision of tarsus and skin
+∞
16.8
16
*
ZXA00
NOMESCO Finland
Right side
2.4
16.7
169
900
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
14.1
16.7
28
21
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
12.9
16.0
28
23
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
62.2
15.9
18
*
CG2S4
NOMESCO Finland
Photography of cornea
27.4
15.7
21
8
R4120
NOMESCO Finland
Occupational therapy
3.7
15.7
53
156
H53.2
ICD-10 Finland
Diplopia
5.1
15.7
34
71
S01XA18
ATC
ciclosporin; ophthalmic
88.0
15.7
17
*
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
88.0
15.7
17
*
AA1AD
NOMESCO Finland
CT of head and brain
2.2
15.4
193
1117
R4110
NOMESCO Finland
Physiotherapy
2.3
15.3
166
905
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
15.2
155
823
ZXE00
NOMESCO Finland
One hour or less
2.2
14.9
213
1294
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
14.8
14.7
24
17
CBG99
NOMESCO Finland
Other operation for trichiasis
+∞
14.7
14
*
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
+∞
14.7
14
*
D33.3
ICD-10 Finland
Benign neoplasm: Cranial nerves
+∞
14.7
14
*
CBF20
NOMESCO Finland
Resection of part of tarsus for ectropion
+∞
14.7
14
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.6
14.6
100
443
CD2S4
NOMESCO Finland
Photography of eye
23.1
14.3
20
9
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
14.3
103
467
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
43.9
14.2
17
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
4.6
14.0
34
78
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.6
14.0
49
148
CBH40
NOMESCO Finland
Division of tarsorrhaphy
+∞
13.6
13
*
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
13.6
13
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.5
13.6
100
457
CBB50
NOMESCO Finland
Excision of lesion of eyelid and reconstruction using graft or flap
41.3
13.2
16
*
S01AA01
ATC
chloramphenicol; ophthalmic
3.9
13.0
40
110
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
12.7
217
1388
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.2
12.6
26
52
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
+∞
12.6
12
*
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
+∞
12.6
12
*
TCB10
NOMESCO Finland
Simple epilation of cilia
+∞
12.6
12
*
CBN20
NOMESCO Finland
Shortening of eyelid retractors
+∞
12.6
12
*
3742A
ICD-9 Finland
Other disorders of eyelids, Lagophthalmos
+∞
12.6
12
*
AAH50
NOMESCO Finland
Cranial nerve anastomosis
+∞
12.6
12
*
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
+∞
12.6
12
*
CG2T4
NOMESCO Finland
Topography assessment of cornea
13.7
12.5
21
16
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.0
12.4
36
95
Z3226
NOMESCO Finland
Physiotherapist
2.3
12.3
109
539
R13
ICD-10 Finland
Dysphagia
3.1
12.1
54
189
Z3231
NOMESCO Finland
Registered nurse
2.1
11.7
155
898
H04.2
ICD-10 Finland
Epiphora
66.6
11.7
13
*
CBW99
NOMESCO Finland
Other operation on eyelid
66.6
11.7
13
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
11.5
11.6
21
19
WX402
NOMESCO Finland
General anaesthesia
2.2
11.6
120
632
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.6
11.6
28
64
CBC10
NOMESCO Finland
Removal of foreign body from eyelid
122.8
11.5
12
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
12.2
11.4
20
17
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
11.4
197
1253
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
11.3
196
1246
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.7
11.1
36
103
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
3.6
11.1
38
113
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
14.3
11.0
18
13
CBD10
NOMESCO Finland
Plastic reconstruction of eyelid using graft or flap
61.4
10.7
12
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
9.5
10.6
21
23
ZXD20
NOMESCO Finland
Day surgery
2.4
10.6
77
348
ZZA00
NOMESCO Finland
Split skin graft
4.2
10.6
28
69
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
10.5
86
410
AAE32
NOMESCO Finland
Translabyrinthine excision acoustic neurinome
112.4
10.5
11
*
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
112.4
10.5
11
*
XCK00
NOMESCO Finland
Perimetry
3.1
10.4
44
149
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.3
10.3
88
426
J01DB01
ATC
cefalexin; oral
2.3
10.2
402
3327
ZZF00
NOMESCO Finland
Graft of adipose tissue
13.5
10.2
17
13
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
17.2
9.9
15
9
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
12.5
9.9
17
14
R4190
NOMESCO Finland
Nutritional therapy
4.1
9.9
27
68
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
3.0
9.7
43
150
S01AD03
ATC
aciclovir; ophthalmic
4.6
9.6
23
52
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.5
9.6
34
103
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.3
9.6
79
377
F01
ICPC
Eye pain
4.5
9.4
23
53
H00.1
ICD-10 Finland
Chalazion
7.2
9.4
22
32
CBN00
NOMESCO Finland
Eversion suture of eyelid
+∞
9.4
9
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
9.4
9
*
2251A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cranial nerves
+∞
9.4
9
*
CBG20
NOMESCO Finland
Plastic repair of margin of eyelid for trichiasis
+∞
9.4
9
*
Z2221
NOMESCO Finland
Medical doctor
1.9
9.2
139
833
G51.8
ICD-10 Finland
Other disorders of facial nerve
37.4
9.1
11
*
SPAT1153
SPAT
Removal of sutures
1.8
8.6
172
1125
U13
ICPC
Bladder symptom/complaint other
3.8
8.6
26
71
R4130
NOMESCO Finland
Speech therapy
4.4
8.5
21
49
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
91.6
8.4
9
*
CBB00
NOMESCO Finland
Excision of chalazion
91.6
8.4
9
*
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.7
8.4
27
77
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
+∞
8.4
8
*
H05.2
ICD-10 Finland
Exophthalmic conditions
+∞
8.4
8
*
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
+∞
8.4
8
*
QAJ15
NOMESCO Finland
Browlift using video-endoscope
+∞
8.4
8
*
TQA05
NOMESCO Finland
Puncture of skin of head or neck
+∞
8.4
8
*
9560/0-C72.5
ICD-O-3
Schwannoma, NOS, of cranial nerve, NOS
+∞
8.4
8
*
CBK10
NOMESCO Finland
Operation for lagophtalmus
+∞
8.4
8
*
D33.37
ICD-10 Finland
Another benign tumor of the cranial nerves
+∞
8.4
8
*
H16.4
ICD-10 Finland
Corneal neovascularization
+∞
8.4
8
*
CBG10
NOMESCO Finland
Cryotherapy for trichiasis
+∞
8.4
8
*
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
+∞
8.4
8
*
EKC20
NOMESCO Finland
Plastic repair of cheek
+∞
8.4
8
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
14.8
8.2
13
9
N02BF02
ATC
pregabalin; oral
2.8
8.2
43
165
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
17.5
8.1
12
7
C07.70
ICD-10 Finland
Malignant tumor of the superficial part of the parotid gland
34.0
8.1
10
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.1
8.0
22
56
L28
ICPC
Limited function/disability (L)
1.9
8.0
122
731
X58
ICD-10 Finland
Exposure to other specified factors
2.1
7.8
77
395
H02AB06
ATC
prednisolone; systemic
1.7
7.8
238
1747
QAE30
NOMESCO Finland
Excision and repair of surgical scar in head or neck
45.7
7.7
9
*
H16.8
ICD-10 Finland
Other keratitis
45.7
7.7
9
*
WF002
NOMESCO Finland
Radical radiotherapy
2.8
7.7
38
141
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
7.6
72
362
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
18.7
7.6
11
6
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
7.6
104
599
CAC10
NOMESCO Finland
Reconstruction of orbital wall using bone graft or plate
25.5
7.6
10
*
GBB00
NOMESCO Finland
Tracheostomy
10.3
7.6
14
14
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.3
7.5
61
289
H02.8
ICD-10 Finland
Other specified disorders of eyelid
81.3
7.4
8
*
A28
ICPC
Limited function/disability NOS
1.9
7.3
117
709
CBN40
NOMESCO Finland
Excision of tarsus
+∞
7.3
7
*
CBH99
NOMESCO Finland
Other operation on canthus
+∞
7.3
7
*
CBN60
NOMESCO Finland
Excision of scar of eyelid and plastic reconstruction
+∞
7.3
7
*
QAJ35
NOMESCO Finland
Other correction of loose or redundant skin of head or neck
+∞
7.3
7
*
37813
ICD-8 Finland
Other diseases of eye, Lagophthalmus
+∞
7.3
7
*
CBE20
NOMESCO Finland
Shortening of eyelid retractors for entropion
+∞
7.3
7
*
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
7.5
7.2
16
22
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.7
7.2
180
1242
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
7.2
87
480
K02.1
ICD-10 Finland
Caries of dentine
1.7
7.1
259
1974
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
12.3
7.1
12
10
CBA10
NOMESCO Finland
Biopsy of eyelid
9.0
7.1
14
16
S01ED01
ATC
timolol; ophthalmic
3.5
7.1
24
71
S01EE05
ATC
tafluprost; ophthalmic
3.1
7.0
29
97
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
3.5
6.9
24
72
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
14.0
6.9
11
8
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.7
6.9
37
144
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
6.9
6.9
16
24
SAA04
NOMESCO Finland
Special examination of mouth
3.0
6.8
30
105
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.6
6.7
246
1868
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.6
6.7
40
164
S01EE01
ATC
latanoprost; ophthalmic
2.5
6.7
44
189
N03AX16
ATC
[U] pregabalin
1.8
6.7
116
719
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.1
6.7
18
45
S01EA05
ATC
brimonidine; ophthalmic
3.7
6.7
21
59
TCG10
NOMESCO Finland
Removal of sutures from cornea
12.5
6.6
11
9
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
4.3
6.6
17
41
XKD00
NOMESCO Finland
Uroflowmetry
1.9
6.6
89
509
ZZR00
NOMESCO Finland
Flap of skin
3.9
6.6
19
50
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
6.5
320
2610
ZZK00
NOMESCO Finland
Graft of nerve
70.8
6.4
7
*
H00.03
ICD-10 Finland
Preseptal cellulite in the eyelid
70.8
6.4
7
*
H17.8
ICD-10 Finland
Other corneal scars and opacities
70.8
6.4
7
*
R50.9
ICD-10 Finland
Fever, unspecified
1.9
6.4
81
453
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
4.2
6.4
17
42
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
6.4
97
576
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
6.3
194
1404
CBK00
NOMESCO Finland
Myotomy or resection of tarsal muscle or levator muscle of eyelid for correction of retraction
+∞
6.3
6
*
AAE34
NOMESCO Finland
Other operations on acoustical nerv
+∞
6.3
6
*
CBJ99
NOMESCO Finland
Other operation for ptosis
+∞
6.3
6
*
EKC99
NOMESCO Finland
Other reconstructive operations on cheek
+∞
6.3
6
*
CBF30
NOMESCO Finland
Excision of tarsus and skin for ectropion
+∞
6.3
6
*
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
+∞
6.3
6
*
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
7.2
6.3
14
20
RD210, ,
NOMESCO Finland
7.2
6.3
14
20
H17.1
ICD-10 Finland
Other central corneal opacity
27.1
6.2
8
*
N91
ICPC
Facial paralysis/bell's palsy
27.1
6.2
8
*
EAB20
NOMESCO Finland
Plastic repair of lip
27.1
6.2
8
*
DFF00
NOMESCO Finland
Pure tone audiometry
2.1
6.2
65
339
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
6.2
71
383
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.9
6.2
88
512
S01ED51
ATC
timolol, combinations; ophthalmic
2.2
6.2
50
236
XCH05
NOMESCO Finland
Eye pressure longterm registration
7.8
6.2
13
17
R42
ICD-10 Finland
Dizziness and giddiness
1.7
6.2
124
801
TAB00
NOMESCO Finland
Lumbar puncture
3.0
6.1
27
94
N02BE01
ATC
paracetamol; systemic, rectal
2.2
6.1
434
3896
R5120
NOMESCO Finland
Preparation of an aid
3.0
6.1
26
89
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.8
6.1
110
689
R33
ICD-10 Finland
Retention of urine
2.2
6.1
54
265
J01MA02
ATC
ciprofloxacin; systemic
1.6
6.1
196
1432

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
142
510
3.53
32.26
2.3
1.6
—
—
—
0
0
77
259
3.35
18.69
2.7
2.5
10.63
19.11
au/ml
—
6
17
68
232
3.25
16.05
1.5
1.4
48.52
51.69
au/ml
—
5
21
24
38
6.59
14.69
1.8
1.1
—
—
—
0
0
252
1650
2.11
14.32
3.2
2.2
—
—
—
0
0
33
75
4.65
13.77
1.7
1.2
—
—
—
0
0
180
1054
2.13
13.57
3.9
2.5
—
—
—
0
0
35
87
4.26
13.06
1.6
1.2
182.62
20.94
e6/l
0.87
26
67
35
89
4.16
12.68
1.7
1.3
600.96
142.90
e6/l
0.53
26
70
285
2012
2.02
12.55
6.7
4.8
34.78
35.16
g/l
0.60
268
1883
87
395
2.47
11.88
10.4
7.3
—
—
—
0
0
207
1340
1.96
11.36
5.0
4.3
—
—
—
0
0
213
1395
1.95
11.27
4.1
2.6
—
—
—
0
0
289
2098
1.95
11.20
10.0
6.1
1.21
1.21
mmol/l
0.14
267
1936
137
775
2.07
10.94
4.2
3.1
1.17
1.06
e6/l
0.21
74
409
87
410
2.37
10.90
1.6
1.4
—
—
—
0
0
135
786
2.00
9.82
3.5
3.0
0.82
0.81
mmol/l
0.30
128
745
195
1285
1.87
9.77
5.1
3.2
0.23
0.41
e6/l
1.47
151
953
316
2425
1.88
9.66
13.1
9.6
4.44
4.22
e9/l
0.39
269
2134
228
1599
1.81
9.18
4.0
3.6
2.35
2.35
mmol/l
0.21
210
1447
304
2326
1.83
9.14
11.9
7.0
1.21
1.21
mmol/l
0.08
270
2001
153
958
1.88
8.83
2.9
3.0
2.47
2.46
mmol/l
0.34
139
874
110
618
2.01
8.74
8.7
5.0
1.07
1.04
mmol/l
0.52
104
564
284
2162
1.77
8.34
8.3
5.6
0.61
0.59
e9/l
0.42
241
1859
285
2172
1.77
8.34
8.3
5.6
0.05
0.04
e9/l
1.77
242
1874
205
1423
1.77
8.32
7.9
5.5
—
—
—
0
0
81
418
2.13
8.05
2.3
2.0
385.03
386.39
nmol/l
0.02
75
391
266
2001
1.74
8.03
8.4
5.7
58.43
58.28
%
0.07
257
1906
162
1061
1.79
7.94
3.8
2.6
4.61
5.73
e6/l
0.58
143
984
212
1503
1.73
7.87
5.3
3.4
69.89
65.39
e6/l
0.05
171
1167
265
1999
1.73
7.85
8.7
5.8
8.70
8.87
%
0.37
252
1875
256
1913
1.72
7.85
3.1
2.5
79.90
78.12
nmol/l
0.49
234
1701
286
2207
1.73
7.77
8.5
5.7
1.90
1.96
e9/l
0.19
246
1956
113
666
1.91
7.73
2.6
1.9
—
—
—
0
0
119
715
1.88
7.67
4.3
3.2
2.97
2.68
e6/l
0.11
54
349
267
2030
1.71
7.58
8.6
5.8
25.82
26.55
%
0.42
256
1927
264
2002
1.71
7.56
8.5
5.7
2.73
2.83
%
0.33
251
1872
263
1996
1.70
7.48
8.6
5.8
0.69
0.67
%
0.28
251
1863
69
344
2.17
7.47
2.9
2.6
—
—
—
0
0
288
2241
1.71
7.45
8.5
5.8
0.20
0.19
e9/l
0.41
248
1959
264
2007
1.70
7.45
4.1
2.8
—
—
estimate
—
0
0
201
1429
1.70
7.22
2.4
2.1
170.43
214.60
u/l
0.72
196
1352
153
1018
1.74
6.95
5.9
4.0
—
0.17
—
0
12
321
2614
1.69
6.62
7.4
4.8
6.62
6.76
mmol/l
0.84
306
2487
113
698
1.81
6.58
3.7
2.5
20.77
21.60
%
0.22
102
647
279
2203
1.63
6.39
14.2
16.1
1.25
1.28
inr
0.39
217
1851
108
664
1.81
6.37
9.5
6.1
104.08
104.16
mmol/l
0.06
108
664
193
1400
1.63
6.18
6.8
4.1
7.39
7.40
ph
0.69
140
1022
76
422
1.95
6.13
3.1
2.9
65.85
66.57
g/l
0.33
67
390
441
3987
2.28
6.05
28.4
17.5
28.50
25.62
mg/l
1.04
396
3347
175
1248
1.63
5.95
8.4
6.3
—
—
—
0
0
195
1435
1.60
5.79
2.2
1.7
20.94
20.21
nmol/l
0.26
171
1189
68
371
1.97
5.76
5.3
3.5
108.59
81.89
ng/l
0.58
63
318
124
816
1.70
5.71
3.7
2.5
11.25
12.46
umol/l
1.04
115
755
117
758
1.72
5.71
3.6
2.4
2.15
2.28
g/l
1.71
108
699
17
37
4.72
5.53
1.9
1.2
—
—
—
0
0
218
1663
1.57
5.47
6.4
4.0
88.43
98.30
e6/l
0.11
170
1204
16
43
3.81
5.41
2.4
2.9
772.19
789.26
mg
0.01
16
43
23
80
2.97
5.26
3.7
1.7
4.10
85.76
iu/l
—
10
28
90
553
1.77
5.26
1.8
1.6
—
—
—
0
0
91
564
1.76
5.16
10.2
6.7
7.40
7.42
ph
1.04
48
345
168
1223
1.57
5.08
3.2
2.3
2.84
3.00
mg/l
0.34
144
1056
193
1452
1.55
5.04
4.9
3.4
—
—
—
0
0
290
2386
1.54
5.01
8.4
6.6
10.15
11.81
umol/l
2.69
280
2268
85
521
1.77
5.00
1.5
1.4
—
—
—
0
0
87
539
1.75
4.93
1.4
1.3
489.41
484.96
titre
0.01
17
129
131
908
1.61
4.84
3.3
2.9
516.51
528.78
mosm/kgh2o
0.28
113
805
14
29
4.94
4.84
1.3
1.1
3.11
1.87
mmol/l
0.92
14
29
376
3295
1.65
4.83
12.0
8.4
82.72
81.44
u/l
0.20
363
3107
89
560
1.72
4.77
10.3
6.7
1.80
0.93
mmol/l
1.66
73
468
90
569
1.72
4.74
10.4
6.6
5.21
5.05
kpa
1.03
85
550
90
570
1.71
4.71
10.4
6.6
14.21
12.02
kpa
2.51
85
553
29
122
2.47
4.66
1.2
1.8
—
—
—
0
0
414
3734
1.78
4.63
6.7
5.4
1.80
1.99
mu/l
2.86
381
3393
67
396
1.80
4.44
1.7
1.4
—
—
—
0
0
78
486
1.72
4.32
4.6
3.4
2.31
2.01
mmol/l
0.32
70
407
81
511
1.70
4.29
4.4
3.5
7.36
7.38
ph
3.27
45
307
27
115
2.43
4.24
3.2
2.3
12.61
13.96
mg/l
0.33
27
107
26
109
2.46
4.22
2.9
3.5
1.63
1.49
index
0.06
19
59
86
556
1.67
4.15
1.6
1.3
—
—
—
0
0
438
4048
1.92
4.11
21.1
16.1
—
—
—
0
0
78
494
1.69
4.07
1.8
1.5
—
—
—
0
0
13
31
4.28
4.04
1.2
1.1
—
—
—
0
0
184
1423
1.47
4.00
2.9
2.5
53.53
117.59
u/l
0.59
172
1308
35
173
2.10
3.90
2.0
2.2
10.06
10.48
g/l
0.15
28
156
247
2031
1.44
3.85
2.9
2.2
91.72
95.54
pmol/l
0.70
127
1061
91
609
1.61
3.82
1.3
1.2
—
—
—
0
0
16
55
2.97
3.77
2.4
2.5
—
—
—
0
0
44
241
1.91
3.71
1.6
1.9
1.71
1.47
g/l
0.72
37
214
66
410
1.71
3.69
2.6
2.5
5.55
6.39
ug/l
0.25
57
366
21
85
2.54
3.68
1.3
1.3
5.81
10.14
u/l
2.04
15
68
14
40
3.57
3.63
1.3
1.5
0.14
0.26
nmol/l
—
8
30
90
611
1.58
3.56
2.8
2.6
1.70
1.80
%
0.46
82
540
229
1880
1.42
3.48
14.4
12.2
0.00
0.00
e9/l
0.31
176
1557
32
163
2.03
3.33
4.4
3.6
1.39
5.25
ratio
0.95
22
89
331
2913
1.44
3.32
6.4
4.7
—
1.61
—
0
5
354
3157
1.46
3.29
5.4
4.3
15.07
15.02
pmol/l
0.16
319
2849
235
1959
1.39
3.17
4.4
3.0
123.41
135.51
ug/l
0.42
216
1808
66
428
1.63
3.15
3.1
2.1
0.57
0.00
estimate
—
7
79
9
20
4.56
3.12
1.0
1.1
—
—
—
0
0
452
4276
1.95
3.11
41.7
26.9
251.47
246.08
e9/l
0.80
446
4190
11
30
3.73
3.10
1.1
1.3
—
—
—
0
0
452
4278
1.94
3.08
41.6
26.8
4.34
4.43
e12/l
3.14
447
4180
452
4278
1.94
3.08
41.7
26.9
7.13
6.87
e9/l
0.63
446
4179
113
832
1.47
3.05
1.7
1.8
1091.30
1233.24
nmol/l
0.88
80
617
443
4174
1.78
2.96
17.6
12.7
24.80
24.97
u/l
0.09
431
4042
12
37
3.30
2.95
2.0
1.5
10.15
10.23
%
0.02
12
37
117
873
1.45
2.94
5.5
3.9
532.98
283.91
ng/l
0.36
96
719
8
17
4.77
2.93
1.1
1.1
—
—
—
0
0
17
70
2.48
2.91
1.8
1.4
—
—
—
0
0
217
1806
1.37
2.87
5.4
3.6
6.34
6.21
ph
0.82
102
1019
15
59
2.59
2.81
1.4
1.2
—
—
—
0
0
189
1544
1.37
2.79
2.9
3.4
1859.97
1474.89
ng/l
0.55
161
1343
16
66
2.47
2.73
1.1
1.0
—
—
—
0
0
71
485
1.54
2.73
3.0
2.8
62.24
69.00
e9/l
0.92
50
369
9
24
3.80
2.68
1.0
1.5
—
—
—
0
0
124
951
1.41
2.66
1.7
1.6
1.18
1.42
mg/l
0.75
93
766
23
113
2.09
2.66
5.3
4.3
—
—
—
0
0
71
488
1.53
2.66
3.1
2.6
8.36
9.10
umol/l
0.13
66
436
15
61
2.51
2.64
1.7
1.3
174.40
160.46
au/ml
—
5
16
74
514
1.52
2.64
3.8
4.5
3.44
31.60
ug/l
1.18
57
435
11
36
3.10
2.58
2.3
1.9
25.40
67.63
ng/l
0.69
11
36
261
2264
1.33
2.52
5.8
4.1
0.00
0.00
estimate
0.50
44
513
265
2304
1.33
2.51
5.8
4.2
0.13
0.01
estimate
0.57
40
492
18
82
2.24
2.50
1.3
1.1
—
—
—
0
0
8
21
3.86
2.47
2.0
3.4
0.38
0.86
index
—
8
21
17
76
2.28
2.47
1.1
1.1
—
—
—
0
0
41
252
1.69
2.43
1.8
1.3
—
—
—
0
0
7
17
4.16
2.36
1.0
1.1
—
—
—
0
0
58
395
1.53
2.28
5.5
4.3
1.00
0.53
%
0.47
23
134
17
80
2.17
2.21
5.3
2.4
15.53
8.73
pmol/l
0.56
17
80
8
24
3.37
2.19
1.4
1.0
264.25
241.67
mg/l
—
8
24
31
182
1.75
2.17
1.1
1.1
—
—
—
0
0
9
30
3.04
2.15
1.9
1.8
37.67
36.02
%
—
9
30
6
14
4.33
2.15
1.5
1.9
31.83
28.21
%
—
6
14
18
88
2.09
2.14
2.3
1.7
279.83
300.33
mu/l
0.17
18
81
212
1816
1.30
2.12
4.1
4.1
37.64
85.49
ng/l
0.78
170
1410
18
89
2.06
2.08
1.8
2.0
4.65
4.38
mmol/24h
0.10
18
78
5
10
5.04
2.07
1.2
1.1
0.65
0.62
mmol/l
—
5
10
259
2283
1.29
2.06
5.9
4.1
0.00
3.56
estimate
0.50
44
528
57
396
1.50
2.05
5.7
4.5
0.14
0.15
%
0.02
21
122
103
801
1.36
2.01
1.8
1.3
2.36
2.64
g/l
0.82
60
474
115
1424
0.75
1.99
2.8
3.5
—
—
—
0
0
5
11
4.58
1.94
1.6
1.1
—
—
—
0
0
13
58
2.28
1.92
2.8
2.6
1.47
1.44
g/24h
—
8
31
59
419
1.47
1.92
5.9
4.4
1.09
1.10
%
0.01
23
146
56
395
1.47
1.89
3.5
2.4
32.62
33.44
u/l
0.07
50
334
165
1393
1.28
1.78
3.6
3.3
37.13
33.09
u/l
0.58
157
1300
17
88
1.97
1.77
1.6
1.5
—
—
—
0
0
21
118
1.82
1.73
1.1
1.2
—
—
—
0
0
135
1116
1.29
1.71
1.4
1.4
—
—
—
0
0
47
328
1.48
1.68
4.1
3.5
7.41
7.42
ph
0.20
32
277
35
229
1.57
1.68
4.6
3.6
—
—
—
0
0
18
98
1.87
1.64
1.2
1.3
—
—
—
0
0
10
42
2.41
1.62
1.7
1.3
—
—
—
0
0
60
444
1.40
1.59
6.1
4.1
7.39
7.36
ph
2.30
43
318
18
101
1.81
1.51
1.9
3.5
53.01
427.01
u/ml
0.85
18
96
102
1237
0.78
1.46
4.4
3.6
0.03
0.01
estimate
0.27
37
410
109
894
1.28
1.46
1.3
1.3
1.02
1.77
u/ml
0.78
31
234
56
416
1.39
1.46
5.8
4.7
0.06
0.16
%
0.53
18
121
7
28
2.52
1.45
1.1
1.2
—
—
—
0
0
34
230
1.51
1.43
2.4
2.4
—
—
—
0
0
37
256
1.48
1.41
1.1
1.3
—
—
—
0
0
10
46
2.20
1.40
1.0
1.2
—
—
—
0
0
134
1133
1.25
1.40
3.8
2.8
353.40
349.09
umol/l
0.18
119
986
7
29
2.43
1.39
4.1
1.5
197.29
93.39
ng/l
—
7
29
409
3902
1.32
1.39
6.2
5.5
5.92
6.02
mmol/l
0.98
377
3515
0
39
0.00
1.34
0.0
2.7
—
—
—
0
0
0
39
0.00
1.34
0.0
1.2
—
—
—
0
0
9
43
2.11
1.31
1.2
1.2
—
—
—
0
0
6
24
2.52
1.30
1.0
1.5
190.33
182.86
mmol/24h
—
6
24
13
70
1.88
1.25
2.9
3.1
—
—
—
0
0
11
56
1.99
1.23
1.1
1.1
—
11.15
—
0
16
32
224
1.46
1.18
1.3
1.3
—
—
—
0
0
44
327
1.38
1.17
3.5
3.0
122.86
126.50
g/l
0.47
44
316
25
166
1.53
1.17
2.2
2.0
4.88
8.18
iu/ml
—
6
47
6
130
0.45
1.17
2.7
4.5
—
—
—
0
0
26
175
1.51
1.15
3.8
3.9
26.31
25.19
mmol/l
0.34
21
163
11
58
1.92
1.13
1.2
1.2
—
—
—
0
0
7
30
2.35
1.12
1.1
1.2
—
—
—
0
0
7
30
2.35
1.12
1.3
2.0
—
—
—
0
0
69
555
1.28
1.09
3.3
3.3
3.81
4.90
e9/l
1.33
56
475
5
21
2.40
1.09
1.8
1.8
1115.40
999.00
u/ml
—
5
21
414
3986
1.28
1.07
6.7
6.2
2.55
2.63
mmol/l
1.02
386
3635
42
315
1.37
1.07
2.0
2.5
12.70
13.24
nmol/l
0.13
36
275
21
137
1.56
1.07
1.5
1.5
320.69
275.54
ug/g
0.45
13
79
9
46
1.97
1.04
1.6
1.0
—
—
—
0
0
5
22
2.29
1.03
4.0
3.2
34.00
33.19
umol/l
—
5
16
11
60
1.85
1.03
2.0
2.3
—
—
—
0
0
15
238
0.62
1.03
1.8
1.4
—
—
—
0
0
7
34
2.07
1.03
1.1
1.1
—
—
—
0
0
9
49
1.85
0.99
4.1
3.8
—
—
—
0
0
32
233
1.40
0.98
2.6
2.1
—
—
—
0
0
0
31
0.00
0.96
0.0
1.2
—
352.46
—
0
26
398
3827
1.23
0.96
7.7
6.9
40.47
39.89
mmol/mol
0.63
361
3541
19
126
1.53
0.92
1.8
1.5
12195.31
19664.11
e6/l
0.44
13
93
6
30
2.01
0.87
1.0
1.1
—
—
—
0
0
97
835
1.20
0.86
3.9
3.4
1.06
0.81
ug/l
1.19
68
565
58
474
1.25
0.83
2.1
2.2
156.22
130.97
ug/g
0.25
44
367
26
190
1.39
0.81
3.0
2.8
—
—
—
0
0
22
156
1.43
0.80
1.4
1.3
—
—
—
0
0
14
90
1.57
0.79
1.1
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.0
—
—
—
0
0
29
218
1.35
0.77
2.8
2.0
0.00
0.00
estimate
—
6
63
32
411
0.76
0.75
1.6
1.6
—
—
—
0
0
403
3905
1.20
0.74
5.8
5.4
4.46
4.55
mmol/l
1.01
375
3574
28
366
0.75
0.74
7.9
3.9
—
—
—
0
0
277
2612
1.14
0.74
4.0
3.3
48.97
52.78
u/l
0.48
258
2418
9
55
1.65
0.74
1.2
1.4
—
—
—
0
0
9
55
1.65
0.74
1.2
1.4
—
—
—
0
0
9
55
1.65
0.74
1.2
1.4
—
—
—
0
0
9
55
1.65
0.74
1.2
1.4
—
—
—
0
0
7
41
1.72
0.70
1.1
1.2
—
—
—
0
0
160
1459
1.14
0.70
6.6
6.0
3.35
3.59
ug/l
0.08
140
1287
112
995
1.16
0.70
6.2
4.4
1.02
1.02
kg/l
0.24
73
671
5
27
1.86
0.68
2.6
4.2
77.60
175.26
nmol/l
—
5
27
5
27
1.86
0.68
7.0
2.1
—
—
—
0
0
38
307
1.26
0.63
1.2
1.2
—
—
—
0
0
5
30
1.67
0.61
1.6
2.5
23.40
30.28
mg/l
—
5
25
170
1571
1.13
0.60
4.2
3.4
6.98
7.23
mmol/l
0.35
140
1297
144
1319
1.13
0.58
6.4
4.2
0.05
0.01
estimate
0.42
37
476
10
147
0.67
0.54
5.5
3.1
1.70
1.67
mmol/l
—
10
142
105
947
1.14
0.54
6.3
4.7
—
—
—
0
0
9
62
1.46
0.53
1.6
1.6
—
—
—
0
0
29
233
1.26
0.52
1.5
1.1
104.09
110.04
u/ml
0.04
11
82
6
40
1.51
0.51
1.7
1.2
147.33
102.38
pmol/l
—
6
40
7
46
1.53
0.48
1.3
1.1
—
—
—
0
0
7
46
1.53
0.48
1.3
1.1
—
—
—
0
0
14
104
1.36
0.43
1.2
2.0
42.71
43.15
nmol/l
0.02
14
97
0
16
0.00
0.41
0.0
1.1
—
172.31
—
0
16
8
60
1.34
0.40
1.4
2.1
84.72
89.55
%
—
8
60
8
111
0.72
0.37
1.1
1.1
—
—
—
0
0
180
1707
1.09
0.37
2.0
1.9
1.34
1.33
mmol/l
0.09
148
1386
77
700
1.12
0.37
1.3
1.3
6.25
9.06
u/ml
0.25
24
269
162
1531
1.09
0.36
4.4
3.5
76.58
50.74
mg/l
0.52
122
981
5
77
0.65
0.36
1.4
1.3
—
—
—
0
0
5
78
0.64
0.36
1.4
1.3
—
—
—
0
0
5
78
0.64
0.36
1.4
1.3
—
—
—
0
0
5
78
0.64
0.36
1.4
1.3
—
—
—
0
0
396
3886
1.11
0.35
5.7
5.3
1.41
1.47
mmol/l
2.10
368
3531
16
129
1.25
0.30
5.9
10.6
—
—
—
0
0
7
56
1.25
0.29
3.0
2.5
—
—
—
0
0
7
57
1.23
0.29
1.3
1.4
—
—
—
0
0
54
490
1.11
0.28
1.4
1.3
—
—
—
0
0
9
117
0.76
0.27
4.2
3.4
7.76
7.67
mmol/l
—
9
112
164
1567
1.07
0.27
5.0
4.2
17.15
9.34
mg/mmol
0.70
116
973
15
122
1.24
0.27
2.3
2.2
122.78
124.71
g/l
—
9
100
5
73
0.68
0.26
1.4
1.3
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
5
38
1.32
0.23
2.0
2.0
—
—
—
0
0
5
39
1.28
0.23
1.2
1.1
—
—
—
0
0
5
39
1.28
0.23
1.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
28.20
—
0
10
8
101
0.79
0.21
4.6
2.5
59.75
59.37
%
—
8
101
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
19
164
1.17
0.20
1.8
1.6
0.29
0.32
mg/l
—
6
72
6
48
1.25
0.20
1.3
1.2
—
—
—
0
0
6
48
1.25
0.20
4.8
3.1
29.87
104.67
u/ml
—
6
48
9
111
0.81
0.20
1.1
1.4
—
—
—
0
0
15
127
1.19
0.20
1.0
1.1
—
—
—
0
0
80
759
1.06
0.17
1.4
1.3
30.14
34.29
iu/ml
0.16
22
249
9
79
1.14
0.15
3.3
1.8
33.56
32.29
pg
—
9
79
7
88
0.79
0.14
1.0
1.1
—
0.69
—
0
15
8
96
0.83
0.14
1.0
1.1
1.48
1.57
g/l
—
8
96
8
98
0.81
0.14
1.0
1.1
1.03
0.91
g/l
—
8
98
12
104
1.16
0.12
2.6
3.1
—
—
—
0
0
377
3737
1.04
0.11
5.0
4.5
1.32
1.28
mmol/l
0.46
342
3371
23
212
1.09
0.10
2.4
1.3
—
—
—
0
0
38
359
1.06
0.10
1.8
1.5
—
—
—
0
0
15
135
1.11
0.10
2.3
1.7
—
—
—
0
0
6
56
1.07
0.08
1.0
1.4
—
—
nmol/l
—
0
0
6
56
1.07
0.08
1.3
1.1
—
—
—
0
0
21
226
0.93
0.08
1.7
1.9
3.86
3.53
mmol/l
0.46
15
170
5
61
0.82
0.08
1.4
1.3
—
—
—
0
0
10
88
1.14
0.08
1.4
1.4
—
—
—
0
0
6
71
0.84
0.07
5.2
1.9
11.83
10.59
mmol/l
—
6
71
26
245
1.06
0.07
5.3
3.3
25.14
25.00
mmol/l
0.09
26
237
34
354
0.96
0.05
3.6
2.9
5.82
6.07
ph
1.09
25
252
102
1003
1.02
0.04
1.8
1.8
505.91
21297867.76
pmol/l
0.74
79
817
26
272
0.95
0.04
1.1
1.5
—
—
—
0
0
16
151
1.06
0.03
1.1
1.1
—
—
—
0
0
166
1653
1.01
0.00
4.2
3.9
—
0.67
—
0
6
24
235
1.02
0.00
1.9
1.6
—
—
—
0
0
173
1732
1.00
0.00
5.8
4.2
0.00
0.03
estimate
1.56
33
437
8
86
0.93
-0.00
1.5
1.2
0.71
0.88
nmol/l
—
8
72
0
6
0.00
-0.00
0.0
1.8
—
2.50
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
0.54
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
-0.00
1.2
1.4
4.74
6.55
mmol/l
—
5
54
5
54
0.93
-0.00
2.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
8.0
—
5.03
—
0
7
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.8
—
—
—
0
0
5
49
1.02
-0.00
1.6
1.1
—
—
—
0
0
5
54
0.93
-0.00
1.8
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
16
160
1.00
-0.00
2.6
3.0
459.00
224.36
mg/l
—
8
61
0
6
0.00
-0.00
0.0
1.3
—
73.33
—
0
6
9
90
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
8.13
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
34.13
—
0
7

Mortality – FinRegistry

Association

Association between endpoint H7_LAGOPHTALMOS and mortality.

Females

Parameter HR [95% CI] p-value
H7_LAGOPHTALMOS 1.358 [1.15, 1.61] < 0.001
Birth year 0.997 [0.99, 1.01] 0.529

During the follow-up period (1.1.1998 — 31.12.2019), 392 out of 1238 females with H7_LAGOPHTALMOS died.

Males

Parameter HR [95% CI] p-value
H7_LAGOPHTALMOS 1.744 [1.42, 2.14] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 375 out of 944 males with H7_LAGOPHTALMOS died.

Mortality risk

Mortality risk for people of age

years, who have H7_LAGOPHTALMOS.

N-year risk Females Males
1 0.119% 0.273%
5 0.782% 1.808%
10 2.201% 4.344%
15 4.166% 8.147%
20 6.923% 13.65%

Relationships between endpoints

Index endpoint: H7_LAGOPHTALMOS – Lagophthalmos

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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