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Other and unspecified disorders of adult personality and behaviour

DOID EFO Endpoint Browser PheWeb

F5_PERSOTH

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F68, F69
  • Cause of death: ICD-10 — F68, F69

2 out of 7 registries used, show all original rules.

243

4. Check minimum number of events

None

243

5. Include endpoints

None

243

6. Filter based on genotype QC (FinnGen only)

219

Control definitions (FinnGen only)

Control exclude
F5_PERSOBEH

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2012 998 1001
Only index persons 1845 947 898
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.03
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 30.95 30.95 30.80
Only index persons 29.81 29.99 29.62

-FinnGen-

Key figures

All Female Male
Number of individuals 219 146 73
Unadjusted period prevalence (%) 0.05 0.05 0.03
Median age at first event (years) 34.46 32.71 37.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
226
Matched controls
2260
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F69
ICD-10 Finland
Unspecified disorder of adult personality and behaviour
+∞
144.9
123
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
30.2
105.9
77
38
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
36.2
100.3
67
26
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
18.6
87.0
81
66
N05AH04
ATC
quetiapine; oral
11.2
76.7
134
261
N05AH03
ATC
olanzapine; systemic
14.5
72.8
78
79
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
13.2
69.8
81
92
N03AX09
ATC
lamotrigine; oral
16.8
68.9
65
53
N03AG01
ATC
valproic acid; systemic, rectal
15.3
67.5
68
62
F32.9
ICD-10 Finland
Depressive episode, unspecified
9.9
66.3
110
197
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
15.8
64.7
63
54
N05AA02
ATC
levomepromazine; systemic
20.8
63.6
52
32
F29
ICD-10 Finland
Unspecified nonorganic psychosis
15.5
58.9
57
48
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
9.3
57.6
92
155
N05AX08
ATC
risperidone; systemic
12.7
57.1
64
68
N05AX12
ATC
aripiprazole; systemic
14.2
54.1
55
50
N05AB03
ATC
perphenazine; systemic, rectal
22.2
53.9
42
23
N06AX16
ATC
venlafaxine; oral
7.9
51.7
101
210
N05BA01
ATC
diazepam; systemic, rectal
8.6
49.8
82
141
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
585.1
49.3
47
*
F68.8
ICD-10 Finland
Other specified disorders of adult personality and behaviour
+∞
46.5
43
*
F61.0
ICD-10 Finland
Mixed personality disorders
+∞
46.5
43
*
F68.1
ICD-10 Finland
Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]
+∞
46.5
43
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
10.5
45.8
58
72
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
19.9
45.5
37
22
N03AE01
ATC
clonazepam; systemic
14.2
45.2
45
39
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
6.9
43.4
93
208
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
11.4
43.0
50
55
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
16.7
42.7
38
27
P99
ICPC
Psychological disorders other
14.5
42.2
41
34
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
478.5
41.5
40
*
F60.9
ICD-10 Finland
Personality disorder, unspecified
478.5
41.5
40
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
7.4
38.4
68
124
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
8.9
37.3
53
75
P29
ICPC
Psychological sympt/compl other
6.9
37.0
72
144
N06AB04
ATC
citalopram; systemic
5.8
35.8
91
234
N06AB06
ATC
sertraline; oral
6.1
34.5
79
184
N06AX11
ATC
mirtazapine; oral
5.3
33.9
140
534
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
10.4
32.9
40
46
F99
ICD-10 Finland
Mental disorder, not otherwise specified
13.2
32.5
33
29
N06AB03
ATC
fluoxetine; oral
6.2
32.5
69
149
N03AX16
ATC
[U] pregabalin
5.4
32.4
91
252
ZY010
NOMESCO Finland
Hospital outpatient
8.8
32.2
45
62
N05BA04
ATC
oxazepam; oral
5.0
31.9
112
372
N06AX03
ATC
mianserin; oral
11.6
31.8
35
35
N05CF01
ATC
zopiclone; oral
4.8
30.5
111
377
N07BB01
ATC
disulfiram; oral
9.6
30.5
39
48
N06AX12
ATC
bupropion; oral
6.4
29.9
59
118
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
10.3
29.8
36
41
N05CD07
ATC
temazepam; oral
8.0
29.7
45
68
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
9.0
29.0
39
51
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
5.1
28.5
79
214
N05BE01
ATC
buspirone; oral
11.4
28.0
31
31
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
39.7
27.4
34
10
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
7.4
25.9
42
68
F68.0
ICD-10 Finland
Elaboration of physical symptoms for psychological reasons
+∞
25.5
24
*
N06AB05
ATC
paroxetine; oral
8.0
25.5
38
56
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
101.8
25.3
27
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
7.5
24.8
39
61
IGY02
NOMESCO Finland
Psychiatric monitoring contact
8.8
24.5
33
43
N03AF02
ATC
oxcarbazepine; oral
10.5
24.0
28
30
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
6.5
24.0
44
81
N05AF03
ATC
chlorprothixene; systemic
21.5
23.9
35
19
P76
ICPC
Depressive disorder
5.6
23.6
53
118
N05BA06
ATC
lorazepam; systemic, sublingual
8.8
23.1
31
40
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.3
22.8
54
126
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
9.4
22.8
29
35
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
8.7
22.2
30
39
Z2446
NOMESCO Finland
Social worker
6.4
21.4
39
71
R56.8
ICD-10 Finland
Other and unspecified convulsions
7.4
21.1
33
51
AA1AD
NOMESCO Finland
CT of head and brain
4.0
20.9
83
288
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
4.1
20.7
74
238
N06AX21
ATC
duloxetine; oral
4.6
20.5
59
161
F34.1
ICD-10 Finland
Dysthymia
8.2
20.4
29
40
P01
ICPC
Feeling anxious/nervous/tense
3.9
20.4
85
304
P74
ICPC
Anxiety disorder/anxiety state
5.7
20.4
43
90
N06AB10
ATC
escitalopram; oral
3.7
20.3
99
393
C07AA05
ATC
propranolol; systemic
3.7
19.7
91
348
J45.9
ICD-10 Finland
Asthma, unspecified
4.1
19.5
69
219
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
21.1
19.2
28
15
F60.8
ICD-10 Finland
Other specific personality disorders
206.4
18.8
19
*
P80
ICPC
Personality disorder
206.4
18.8
19
*
N05AD01
ATC
haloperidol; systemic
19.8
18.8
28
16
K59.09
ICD-10 Finland
Constipation, unspecified
7.1
18.5
30
48
C03CA01
ATC
furosemide; systemic
4.4
18.5
56
158
A28
ICPC
Limited function/disability NOS
5.0
18.2
45
108
A06AD11
ATC
lactulose; oral
5.1
18.0
43
100
F31.8
ICD-10 Finland
Other bipolar affective disorders
15.7
17.9
29
21
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
6.8
17.8
30
50
N03AX12
ATC
[U] gabapentin; oral
4.1
17.5
59
180
N05AN01
ATC
lithium; oral
15.8
17.3
28
20
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
6.8
17.3
29
48
TPH04
NOMESCO Finland
Cathetrisation of vein
3.7
17.2
73
261
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
4.2
17.1
55
162
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
6.8
16.8
28
46
Z2445
NOMESCO Finland
Psychologist
6.3
16.5
30
54
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.2
16.5
125
632
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
51.6
16.3
19
*
XF400
NOMESCO Finland
ECG with 12 standard connections
4.4
16.1
47
128
R96
ICPC
Asthma
5.2
15.8
36
80
N05BA12
ATC
alprazolam; oral
4.5
15.8
43
111
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
7.1
15.7
25
39
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.7
15.5
40
99
R55
ICD-10 Finland
Syncope and collapse
4.9
15.2
37
87
S06.0
ICD-10 Finland
Concussion
4.0
15.2
50
149
N03AF01
ATC
carbamazepine; oral, rectal
7.4
15.2
23
34
A01
ICPC
Pain general/multiple sites
4.4
14.8
42
112
R52.9
ICD-10 Finland
Pain, unspecified
4.1
14.7
47
137
R02
ICPC
Shortness of breath/dyspnoea
4.1
14.7
47
137
P03
ICPC
Feeling depressed
3.6
14.7
61
213
N06AA09
ATC
amitriptyline; systemic
5.0
14.6
34
77
F20.9
ICD-10 Finland
Schizophrenia, unspecified
13.2
14.5
25
21
S29
ICPC
Skin symptom/complaint other
3.4
14.5
66
244
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.3
14.4
42
114
IGY99
NOMESCO Finland
Other psychiatric treatment contact
7.3
14.3
22
33
UKC02
NOMESCO Finland
Cystoscopy
4.7
14.3
36
87
N05AH02
ATC
clozapine; systemic
12.6
14.2
25
22
R11
ICD-10 Finland
Nausea and vomiting
4.4
14.1
40
106
R42
ICD-10 Finland
Dizziness and giddiness
3.4
14.0
62
225
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
36.6
13.7
17
5
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
36.6
13.7
17
5
R06.0
ICD-10 Finland
Dyspnoea
3.1
13.7
77
322
F39
ICD-10 Finland
Unspecified mood [affective] disorder
11.6
13.6
25
24
N30.0
ICD-10 Finland
Acute cystitis
3.4
13.5
61
223
R52.2
ICD-10 Finland
Other chronic pain
6.9
13.5
22
35
Z3231
NOMESCO Finland
Registered nurse
3.1
13.5
79
337
L28
ICPC
Limited function/disability (L)
3.8
13.4
48
151
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
11.1
13.4
25
25
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.9
13.3
44
131
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
13.2
111
575
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.7
13.2
22
36
F33.8
ICD-10 Finland
Other recurrent depressive disorders
30.4
13.2
17
6
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.0
13.1
42
122
N02BF02
ATC
pregabalin; oral
4.9
13.1
31
71
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.2
13.0
66
259
WX892
NOMESCO Finland
Monitored bed care
5.3
13.0
28
59
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.1
12.9
72
298
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.4
12.9
36
94
N03AX11
ATC
topiramate; oral
6.5
12.9
22
37
N06AX05
ATC
trazodone; oral
11.0
12.8
24
24
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.0
12.8
41
119
R53
ICD-10 Finland
Malaise and fatigue
2.9
12.7
86
396
P72
ICPC
Schizophrenia
10.6
12.6
24
25
F61
ICD-10 Finland
Mixed and other personality disorders
137.3
12.6
13
*
R03BB04
ATC
tiotropium bromide; inhalant
5.4
12.5
26
53
N02AX02
ATC
tramadol; systemic, rectal
2.7
12.4
112
597
A04
ICPC
Weakness/tiredness general
3.2
12.3
59
223
SPAT1240
SPAT
Therapeutic discussion
3.4
12.3
53
188
SPAT1254
SPAT
Administration of medicine
3.5
12.2
48
160
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
28.5
12.2
16
6
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
49.5
12.0
14
*
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
5.1
12.0
27
59
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
13.6
11.9
20
16
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.4
11.9
51
180
R33
ICD-10 Finland
Retention of urine
9.5
11.9
24
28
N05CF02
ATC
zolpidem; oral
3.1
11.8
59
228
F90.0
ICD-10 Finland
Disturbance of activity and attention
4.1
11.8
35
96
Z72.2
ICD-10 Finland
Drug use
68.6
11.7
13
*
A04AA01
ATC
ondansetron; systemic, rectal
4.8
11.6
28
65
XF600
NOMESCO Finland
Bloodpressure measurement
5.8
11.6
22
41
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
11.6
71
308
F60.0
ICD-10 Finland
Paranoid personality disorder
+∞
11.6
11
*
N04AA02
ATC
biperiden; systemic
16.2
11.5
18
12
X59
ICD-10 Finland
Exposure to unspecified factor
2.9
11.5
68
289
A46
ICD-10 Finland
Erysipelas
3.6
11.4
43
139
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
13.7
11.4
19
15
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
9.4
11.3
23
27
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
5.7
11.3
22
42
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
10.0
11.3
22
24
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
10.0
11.3
22
24
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
14.9
11.2
18
13
N05AB01
ATC
dixyrazine; systemic
45.7
11.0
13
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.4
11.0
46
159
A02BA02
ATC
ranitidine; systemic
3.4
11.0
46
159
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
5.0
11.0
25
55
R4110
NOMESCO Finland
Physiotherapy
2.8
11.0
76
350
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
19.0
10.9
16
9
R51.80
ICD-10 Finland
Headache
2.8
10.9
68
297
ZY000
NOMESCO Finland
Hospital inpatient
13.8
10.9
18
14
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
22.8
10.8
15
7
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
12.1
10.8
19
17
M54.5
ICD-10 Finland
Low back pain
2.5
10.8
114
646
A02BC01
ATC
omeprazole; systemic
2.7
10.7
76
354
Z01.8
ICD-10 Finland
Other specified special examinations
2.8
10.7
69
306
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.6
10.7
27
65
R60.0
ICD-10 Finland
Localized oedema
3.8
10.7
36
108
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
12.9
10.5
18
15
D06
ICPC
Abdominal pain localized other
3.7
10.5
37
114
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
5.5
10.5
21
41
T90
ICPC
Diabetes non-insulin dependent
3.0
10.5
54
211
S18
ICPC
Laceration/cut
2.5
10.5
116
669
WZC00
NOMESCO Finland
Treatment plan or consultation
2.5
10.4
104
571
X78
ICD-10 Finland
Intentional self-harm by sharp object
24.7
10.4
14
6
SPAT1307
SPAT
Psychosocial counselling and guidance
3.8
10.3
34
100
G43.9
ICD-10 Finland
Migraine, unspecified
3.6
10.3
38
121
H02AB07
ATC
prednisone; oral
3.5
10.3
40
132
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
5.4
10.3
21
42
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.2
10.2
22
46
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
10.8
10.2
19
19
F10.20
ICD-10 Finland
Alcohol dependence currently independent
10.8
10.2
19
19
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
4.5
10.2
26
63
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.9
10.2
33
96
F41.1
ICD-10 Finland
Generalized anxiety disorder
3.7
10.1
34
102
F41.8
ICD-10 Finland
Other specified anxiety disorders
4.9
10.0
23
51
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.6
10.0
76
365
A97
ICPC
No disease
2.7
9.9
66
296
N05AA01
ATC
chlorpromazine; systemic, rectal
21.2
9.9
14
7
P19
ICPC
Drug abuse
21.2
9.9
14
7
P28
ICPC
Limited function/disability (P)
27.4
9.9
13
5
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
5.7
9.8
19
36
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.1
9.8
29
79
F10.25
ICD-10 Finland
Alcohol dependence continuous use
10.8
9.7
18
18
103
Kela drug reimbursment
Diabetes, insulin-treated
2.8
9.7
58
246
F50.9
ICD-10 Finland
Eating disorder, unspecified
15.9
9.7
15
10
D10
ICPC
Vomiting
3.6
9.6
34
105
K10.3
ICD-10 Finland
Alveolitis of jaws
4.0
9.6
29
80
K59.0
ICD-10 Finland
Constipation
4.7
9.6
23
53
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
5.5
9.5
19
37
J01FF01
ATC
clindamycin; systemic
2.6
9.5
78
387
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
104.2
9.5
10
*
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
104.2
9.5
10
*
N05AD03
ATC
melperone; systemic
104.2
9.5
10
*
N06AX26
ATC
vortioxetine; oral
3.4
9.5
37
122
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
3.4
9.5
37
122
Z91.5
ICD-10 Finland
Personal history of self-harm
+∞
9.4
9
*
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
+∞
9.4
9
*
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.4
9.4
136
870
J01EA01
ATC
trimethoprim; systemic
2.6
9.4
69
325
A10BH01
ATC
sitagliptin; oral
4.6
9.4
23
54
R00.0
ICD-10 Finland
Tachycardia, unspecified
4.8
9.3
22
50
P15
ICPC
Chronic alcohol abuse
5.4
9.3
19
38
H01
ICPC
Ear pain/earache
3.0
9.1
47
183
A03FA01
ATC
metoclopramide; systemic, rectal
2.6
9.1
65
301
Z04.4
ICD-10 Finland
Examination and observation following alleged rape and seduction
38.4
9.1
11
*
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
38.4
9.1
11
*
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
8.5
9.1
19
24
SPAT1167
SPAT
Insertion of urinary catheter
19.6
9.0
13
7
F93.89
ICD-10 Finland
Other childhood emotional disorders
19.6
9.0
13
7
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
19.6
9.0
13
7
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.8
9.0
21
47
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
25.2
9.0
12
5
U07
ICPC
Urine symptom/complaint other
3.9
9.0
28
79
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.4
9.0
83
434
ZXA05
NOMESCO Finland
Left side
2.7
9.0
56
242
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
10.1
8.9
17
18
A10AB05
ATC
insulin aspart; parenteral
4.1
8.9
26
70
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.6
8.9
22
52
G40.9
ICD-10 Finland
Epilepsy, unspecified
8.2
8.8
19
25
XKD00
NOMESCO Finland
Uroflowmetry
4.1
8.8
25
66
TKC20
NOMESCO Finland
Catheterisation of bladder
4.9
8.8
20
44
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
7.5
8.8
20
29
IAB07
NOMESCO Finland
Consultation concerning a patient with self-harm intention
52.1
8.7
10
*
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
52.1
8.7
10
*
Z72.8
ICD-10 Finland
Other problems related to lifestyle
52.1
8.7
10
*
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
52.1
8.7
10
*
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
12.3
8.7
15
13
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
12.3
8.7
15
13
N02AA05
ATC
oxycodone; systemic
3.1
8.7
41
152
SPAT1104
SPAT
Monitoring of emergency patient
4.6
8.6
21
49
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
3.1
8.6
39
141
D01
ICPC
Abdominal pain/cramps general
2.9
8.6
45
177
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
21.0
8.6
12
6
P98
ICPC
Psychosis NOS/other
21.0
8.6
12
6
W17
ICD-10 Finland
Other fall from one level to another
4.8
8.6
20
45
Z3229
NOMESCO Finland
Other healthcare associate professional
3.8
8.5
27
77
A99
ICPC
Disease/condition unspecnature/site
3.2
8.5
38
136
L17
ICPC
Foot/toe symptom/complaint
2.4
8.5
83
443
N05BA02
ATC
chlordiazepoxide; systemic
13.5
8.5
14
11
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.7
8.5
55
242
L12
ICPC
Hand/finger symptom/complaint
2.6
8.5
60
276
IGY02, ,
SPAT
10.0
8.4
16
17
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.7
8.4
52
223
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.4
8.4
33
109
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.3
8.4
35
120
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.5
8.4
21
50
F60.2
ICD-10 Finland
Dissocial personality disorder
+∞
8.4
8
*
L03
ICPC
Low back symptom/complaint
2.3
8.3
88
485
R05
ICPC
Cough
2.4
8.3
79
416
N05CD02
ATC
nitrazepam; oral
15.2
8.3
13
9
X58
ICD-10 Finland
Exposure to other specified factors
2.7
8.3
54
238
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.9
8.3
43
168
F10.09
ICD-10 Finland
Alcohol intoxication UNS
8.7
8.2
17
21
N06BA04
ATC
methylphenidate; oral
3.7
8.2
28
84
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.7
8.2
27
79
P06
ICPC
Sleep disturbance
2.8
8.2
49
206
Z3226
NOMESCO Finland
Physiotherapist
2.8
8.2
49
206
EBA05
NOMESCO Finland
Complicated extraction of tooth
2.4
8.2
74
380
WX290
NOMESCO Finland
Other blockage of nerve
2.3
8.2
152
1056
F31
ICD-10 Finland
Bipolar affective disorder
12.3
8.2
14
12
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
18.0
8.2
12
7
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
34.7
8.1
10
*
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
34.7
8.1
10
*
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
34.7
8.1
10
*
K02.1
ICD-10 Finland
Caries of dentine
2.5
8.1
170
1243
F41.09
ICD-10 Finland
UNS Panic Syndrome
4.6
8.1
20
47
D07AC01
ATC
betamethasone; topical
2.3
8.1
90
506
183
Kela drug reimbursment
Lamotrigin and topiramate
23.0
8.1
11
5
F45.0
ICD-10 Finland
Somatization disorder
23.0
8.1
11
5
N06AA12
ATC
doxepin; systemic
4.7
8.1
19
43
P01AB01
ATC
metronidazole; oral, rectal
2.2
8.1
108
656
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
6.5
8.1
20
33
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
8.0
115
717
A10BA02
ATC
metformin; oral
2.5
8.0
59
276
SAA01
NOMESCO Finland
Simple examination of mouth
3.0
8.0
194
1516
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
13.7
8.0
13
10
B18.2
ICD-10 Finland
Chronic viral hepatitis C
13.7
8.0
13
10
J45
ICD-10 Finland
Asthma
3.2
8.0
35
124
SPAT1216
SPAT
Assessment of functional ability
3.4
7.9
31
102
EBA00
NOMESCO Finland
Extraction of tooth
2.2
7.9
104
625
J46
ICD-10 Finland
Status asthmaticus
11.4
7.9
14
13
IGV01
NOMESCO Finland
Psychiatric network contact
11.4
7.9
14
13
N06AG02
ATC
moclobemide; oral
6.8
7.9
19
30
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
7.9
45
185
U01
ICPC
Dysuria/painful urination
3.5
7.9
29
92
SPAT1058
SPAT
PEF monitoring instruction
4.0
7.8
23
62
SGA02
NOMESCO Finland
Opening and preparing the root canals
2.8
7.8
46
192
A29
ICPC
General symptom/complaint other
3.0
7.8
39
149
Z2221
NOMESCO Finland
Medical doctor
2.3
7.7
74
389
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
3.0
7.7
38
144
R07.4
ICD-10 Finland
Chest pain, unspecified
2.4
7.7
67
338
N06AX17
ATC
milnacipran; oral
19.2
7.7
11
6
A07AA09
ATC
vancomycin; oral
19.2
7.7
11
6
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
7.7
65
324
OAB43, ,
SPAT
0.4
7.6
48
915
N89
ICPC
Migraine
3.6
7.6
26
78
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
10.6
7.6
14
14
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.0
7.6
22
59
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.0
7.6
22
59
SAA04
NOMESCO Finland
Special examination of mouth
3.9
7.5
23
64
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.8
7.5
42
171
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
82.7
7.5
8
*
IAB08
NOMESCO Finland
Consultation concerning a patient who has attempted suicide
82.7
7.5
8
*
U05
ICPC
Urination problems other
7.3
7.4
17
25
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
8.8
7.4
15
18
F10.24
ICD-10 Finland
Alcohol depence active use
9.9
7.4
14
15
G44.2
ICD-10 Finland
Tension-type headache
2.6
7.4
49
217
L05
ICPC
Flank/axilla symptom/complaint
3.8
7.4
23
65
F60.1
ICD-10 Finland
Schizoid personality disorder
+∞
7.3
7
*
F60.7
ICD-10 Finland
Dependent personality disorder
+∞
7.3
7
*
N05AE05
ATC
lurasidone; oral
+∞
7.3
7
*
S51.9
ICD-10 Finland
Open wound of forearm, part unspecified
16.4
7.3
11
7
W0A12
NOMESCO Finland
Planned therapy visit for psychiatric disease
16.4
7.3
11
7
A02BC02
ATC
pantoprazole; systemic
2.2
7.3
152
1085
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.2
7.3
92
541
U04
ICPC
Incontinence urine
7.0
7.3
17
26
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
6.4
7.2
18
30
SPAT1255
SPAT
Intravenous administration of medicine
4.3
7.2
19
47
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.8
7.2
23
66
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.4
7.2
57
275
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
12.6
7.2
12
10
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
9.2
7.2
14
16
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
9.2
7.2
14
16
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
9.2
7.2
14
16
SPAT1262
SPAT
Handing over of treatment supplies
2.8
7.1
38
150
XF404
NOMESCO Finland
Ambulatory ECG
4.0
7.1
21
57
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
4.0
7.1
21
57
A10AE04
ATC
insulin glargine; parenteral
3.3
7.1
28
93
U02
ICPC
Urinary frequency/urgency
2.7
7.0
41
170
M79.1
ICD-10 Finland
Myalgia
2.5
7.0
52
243
R31
ICD-10 Finland
Unspecified haematuria
4.0
7.0
20
53
S61.9
ICD-10 Finland
Open wound of wrist and hand, part unspecified
4.4
7.0
18
44
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.4
7.0
18
44
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
8.7
6.9
14
17
K92.0
ICD-10 Finland
Haematemesis
9.8
6.9
13
14
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.5
6.9
17
40
P04
ICPC
Feeling/behaving irritable/angry
41.3
6.8
8
*
P73
ICPC
Affective psychosis
41.3
6.8
8
*
F44.7
ICD-10 Finland
Mixed dissociative [conversion] disorders
41.3
6.8
8
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.0
6.8
32
118
N06AX22
ATC
agomelatine; oral
6.8
6.8
16
25
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.8
6.8
21
59
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.9
6.8
34
130
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.9
6.8
34
130
SPAT1234
SPAT
Support of social functional capacity
6.2
6.8
17
29
N01
ICPC
Headache
2.4
6.7
53
254
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
23.3
6.7
9
*
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
23.3
6.7
9
*
D12
ICPC
Constipation
8.2
6.7
14
18
M54.4
ICD-10 Finland
Lumbago with sciatica
2.3
6.7
58
290
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.1
6.7
19
50
J01MA02
ATC
ciprofloxacin; systemic
2.1
6.7
86
506
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
12.8
6.7
11
9
F22.0
ICD-10 Finland
Delusional disorder
12.8
6.7
11
9
E66.00
ICD-10 Finland
Metabolic syndrome
3.9
6.6
20
55
WX882
NOMESCO Finland
High dependency care
10.5
6.6
12
12
N07BA03
ATC
varenicline; oral
3.6
6.6
22
65
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.6
6.6
44
195
A03
ICPC
Fever
2.2
6.5
66
353
J45.1
ICD-10 Finland
Nonallergic asthma
3.5
6.5
23
71
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.6
6.5
43
190
X84
ICD-10 Finland
Intentional self-harm by unspecified means
71.8
6.5
7
*
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
14.9
6.5
10
7
ICB06, ,
NOMESCO Finland
14.9
6.5
10
7
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
14.9
6.5
10
7
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
6.9
6.5
15
23
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
5.8
6.4
17
31
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.3
6.4
25
82
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.9
6.4
31
116
A03FA02
ATC
cisapride; oral, rectal
4.1
6.4
18
47
A02BC05
ATC
esomeprazole; systemic
2.1
6.4
94
580
R06AE07
ATC
cetirizine; oral
2.0
6.3
115
764
E66.8
ICD-10 Finland
Other obesity
3.4
6.3
23
72
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.0
6.3
30
111
N05AE04
ATC
ziprasidone; systemic
18.7
6.3
9
5
M89.0
ICD-10 Finland
Algoneurodystrophy
18.7
6.3
9
5
V03AA01, ,
ATC
18.7
6.3
9
5
WX002
NOMESCO Finland
Sedation and analgesia
2.5
6.3
42
186
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
4.2
6.3
17
43
EBA30
NOMESCO Finland
Extraction of root of tooth
4.2
6.3
17
43
F28
ICD-10 Finland
Other nonorganic psychotic disorders
27.5
6.3
8
*
N06AA22, ,
ATC
27.5
6.3
8
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
27.5
6.3
8
*
S21
ICPC
Skin texture symptom/complaint
2.5
6.2
44
200
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
6.2
26
89
M54.8
ICD-10 Finland
Other dorsalgia
4.0
6.2
18
48
N02BF01
ATC
gabapentin; oral
2.8
6.2
33
130
S97
ICPC
Chronic ulcer skin
4.3
6.2
16
39
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.1
6.2
84
502
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
2.1
6.2
74
422
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
13.0
6.1
10
8
F31.3
ICD-10 Finland
Bipolar affective disorder, current episode mild or moderate depression
13.0
6.1
10
8
Y94.8
ICD-10 Finland
Other leisure activity accident
7.0
6.1
14
21
SPAT1257
SPAT
Teaching of medicine inhalation technique
9.0
6.1
12
14
A02BA03
ATC
famotidine; systemic
9.0
6.1
12
14
H03AA01
ATC
levothyroxine sodium; systemic
2.2
6.1
59
308
M35.7
ICD-10 Finland
Hypermobility syndrome
10.4
6.1
11
11
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
6.0
54
273
XF402
NOMESCO Finland
ECG with work load test
3.5
6.0
21
64
SGC00
NOMESCO Finland
Medication, disinfection of root canals
2.6
6.0
39
170
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.7
6.0
19
54
T82
ICPC
Obesity
3.7
6.0
19
54
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
6.0
79
465
F43.20
ICD-10 Finland
Adaptation disorder with short-term depression
7.6
6.0
13
18
WX110, ,
SPAT
3.2
6.0
24
80

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
49
70
8.66
34.12
3.0
1.7
—
—
—
0
0
60
156
4.87
22.27
3.0
1.6
—
—
—
0
0
62
166
4.77
22.19
3.1
1.6
—
—
—
0
0
55
134
5.10
22.05
2.9
1.6
—
—
—
0
0
62
167
4.74
22.01
3.0
1.6
—
—
—
0
0
62
169
4.68
21.66
3.1
1.6
—
—
—
0
0
49
111
5.36
21.32
3.6
1.8
—
—
—
0
0
55
138
4.95
21.24
6.8
11.0
0.49
0.88
mmol/l
0.33
49
118
55
140
4.87
20.85
7.2
11.0
7.41
7.43
ph
0.86
27
82
65
189
4.42
20.84
1.8
1.6
945.65
1198.04
nmol/l
1.86
51
150
137
698
3.44
18.45
5.0
4.8
36.40
37.43
g/l
1.22
131
674
134
674
3.43
18.42
9.0
5.6
1.21
1.21
mmol/l
0.26
124
637
58
169
4.27
18.36
3.2
1.6
—
—
—
0
0
58
170
4.24
18.21
8.3
6.6
104.97
104.63
mmol/l
0.18
58
170
143
752
3.45
18.20
8.8
6.3
1.21
1.21
mmol/l
0.37
126
650
62
194
4.03
17.77
2.2
1.6
—
—
—
0
0
24
13
20.47
16.41
2.1
1.5
—
—
—
0
0
158
928
3.34
15.86
7.4
6.0
9.82
10.56
umol/l
0.38
148
882
111
542
3.06
15.28
4.0
3.2
7.11
8.53
mmol/l
1.91
96
478
113
568
2.98
14.60
4.4
2.8
46.85
64.67
u/l
1.55
103
536
41
111
4.29
14.10
9.3
6.8
—
—
—
0
0
43
122
4.12
13.89
5.3
2.7
7.37
7.39
ph
1.04
23
67
87
390
3.00
13.67
7.7
4.0
—
—
—
0
0
54
182
3.58
13.62
2.8
2.0
340.82
403.93
nmol/l
1.55
49
175
127
706
2.82
13.21
2.5
1.8
94.04
99.00
pmol/l
0.53
72
353
167
1083
3.08
12.79
17.1
9.3
4.59
3.90
e9/l
2.78
142
950
94
456
2.82
12.58
4.8
3.3
7.40
7.40
ph
0.07
66
320
91
443
2.76
11.99
4.7
2.7
0.29
0.18
e6/l
0.34
66
305
156
997
2.82
11.87
11.2
6.4
0.20
0.18
e9/l
0.59
133
894
71
305
2.94
11.82
3.9
2.4
493.77
550.92
mosm/kgh2o
1.25
65
266
91
446
2.74
11.80
4.5
2.7
—
—
estimate
—
0
0
101
531
2.63
11.27
5.2
2.8
23.67
58.13
e6/l
0.63
79
389
109
596
2.60
11.20
9.3
6.0
—
—
—
0
0
150
959
2.68
11.08
10.1
6.1
0.04
0.04
e9/l
0.13
124
849
88
436
2.67
11.04
1.9
1.6
16.41
20.41
nmol/l
2.07
76
387
190
1378
3.38
10.94
10.9
7.3
81.22
75.04
u/l
1.13
181
1308
116
659
2.56
10.93
6.4
3.4
67.49
69.41
e6/l
0.01
84
424
31
82
4.22
10.90
8.2
9.0
1.80
1.32
%
0.93
31
82
149
957
2.63
10.78
9.9
6.1
0.57
0.54
e9/l
0.94
124
848
91
463
2.62
10.77
4.5
2.4
—
—
—
0
0
48
174
3.23
10.63
3.8
2.5
27.86
35.08
u/l
0.63
42
142
30
79
4.23
10.61
8.1
9.2
0.54
0.66
%
0.95
30
79
116
666
2.52
10.60
6.8
8.9
1.06
1.12
inr
1.33
96
551
102
554
2.53
10.46
2.9
3.0
2.34
2.35
mmol/l
0.46
95
519
38
123
3.51
10.04
2.7
1.5
0.22
0.28
mg/l
0.33
17
54
60
256
2.83
9.94
4.0
2.5
5.26
3.10
e6/l
0.35
27
113
27
69
4.31
9.91
4.4
2.1
0.59
0.63
%
0.36
27
69
62
271
2.77
9.80
2.6
2.3
2.40
2.42
mmol/l
0.38
56
245
150
999
2.49
9.54
10.0
6.1
2.08
1.97
e9/l
0.53
132
906
54
224
2.85
9.38
1.9
2.7
8.92
7.85
umol/l
0.11
39
202
138
895
2.39
9.17
10.5
6.3
0.61
0.69
%
0.92
123
844
137
887
2.38
9.12
10.8
6.3
7.91
8.38
%
1.59
123
847
26
70
4.07
8.90
4.6
2.1
2.08
1.46
%
0.93
26
70
137
893
2.36
8.89
10.4
6.1
2.60
2.81
%
0.52
123
847
36
123
3.29
8.71
2.1
1.6
386.77
309.52
mu/l
0.69
31
111
62
287
2.60
8.65
6.0
2.8
38.63
162.34
ng/l
0.81
41
175
26
72
3.95
8.57
4.7
10.7
—
—
—
0
0
70
347
2.47
8.44
4.2
2.4
6.85
5.80
e6/l
0.27
65
312
138
918
2.29
8.33
10.2
5.9
58.00
56.68
%
0.68
127
887
139
928
2.29
8.31
10.4
6.1
28.31
29.29
%
0.52
127
898
18
38
5.06
8.27
3.3
2.4
25.52
24.87
mmol/l
0.22
18
38
83
452
2.32
8.05
2.4
1.9
2.68
2.61
mg/l
0.11
72
397
17
22
8.26
8.04
23.8
16.6
941.82
775.64
nmol/l
0.65
17
22
93
537
2.24
7.80
10.3
6.0
—
—
—
0
0
29
94
3.39
7.60
1.4
1.2
—
—
—
0
0
51
228
2.60
7.56
2.3
2.2
—
—
—
0
0
61
297
2.44
7.56
1.7
1.5
440.58
43494864.78
pmol/l
0.50
50
269
19
48
4.23
7.05
1.5
1.4
—
—
—
0
0
19
49
4.14
6.86
4.5
15.4
0.87
0.85
%
0.08
19
42
27
92
3.20
6.53
8.9
4.8
25.25
24.82
mmol/l
0.28
27
92
77
447
2.10
6.10
4.2
4.1
4.24
10.05
mg/mmol
1.43
52
284
193
1573
2.55
6.05
7.1
4.5
14.33
14.47
pmol/l
0.37
185
1476
21
65
3.46
5.89
2.3
1.9
—
—
—
0
0
123
853
1.97
5.85
15.2
9.8
0.00
0.00
e9/l
0.84
94
711
19
57
3.55
5.58
1.5
1.4
571.11
25.69
e6/l
—
9
45
19
57
3.55
5.58
1.5
1.3
4.33
18.47
e6/l
—
9
43
8
5
16.50
5.45
1.8
2.8
17.94
23.44
umol/l
—
8
5
26
99
2.84
5.19
1.4
1.4
7.04
9.61
u/l
0.61
21
81
14
27
5.45
5.17
1.4
1.6
—
—
—
0
0
74
447
1.97
5.13
3.9
3.5
27.46
68.04
mg/l
1.56
49
291
20
67
3.18
4.97
2.7
1.7
—
—
—
0
0
74
454
1.94
4.87
2.4
1.6
0.80
0.88
mg/l
0.15
57
342
44
223
2.21
4.83
2.0
1.5
—
—
—
0
0
142
1075
1.86
4.78
3.6
3.0
80.52
84.81
ug/l
0.20
133
1037
18
59
3.23
4.63
4.8
2.4
—
—
—
0
0
13
27
5.04
4.57
5.6
1.6
60.46
65.62
%
0.30
13
27
15
45
3.50
4.41
4.4
14.9
1.48
1.28
mmol/l
0.37
15
36
18
61
3.12
4.39
7.9
4.2
36.97
36.92
°c
0.31
18
61
98
675
1.80
4.39
2.7
2.2
—
—
—
0
0
13
29
4.69
4.32
2.6
2.4
8.38
8.10
kpa
0.27
13
29
183
1532
2.02
4.22
6.7
3.2
46.66
40.76
u/l
0.61
174
1491
162
1305
1.85
4.18
7.1
4.1
—
—
—
0
0
55
322
1.94
4.08
2.1
2.6
78.36
125.04
ug/g
1.06
39
248
74
477
1.82
4.07
4.8
2.6
—
—
—
0
0
11
328
0.30
4.07
1.2
1.4
—
—
—
0
0
11
22
5.20
4.06
1.4
1.4
—
—
—
0
0
87
590
1.77
4.04
5.5
2.8
14.21
35.13
ng/l
1.61
55
311
71
453
1.83
4.04
3.7
3.1
1.02
1.02
kg/l
0.03
39
293
30
142
2.28
3.86
4.1
4.5
0.89
0.89
%
—
9
38
19
72
2.79
3.84
1.4
1.4
—
—
—
0
0
110
808
1.70
3.78
2.2
1.9
1.71
1.41
mmol/l
2.10
93
720
29
137
2.28
3.75
4.0
4.4
0.60
0.69
%
—
10
36
58
358
1.83
3.63
2.3
1.6
—
—
—
0
0
9
17
5.46
3.54
1.8
1.5
23.83
20.71
ng/l
—
9
17
26
121
2.30
3.48
4.0
3.4
7.36
7.30
ph
0.80
20
87
28
136
2.21
3.40
4.2
4.6
0.14
0.17
%
—
7
30
11
28
4.07
3.33
3.5
2.0
—
—
—
0
0
41
232
1.94
3.33
1.8
1.6
—
—
—
0
0
206
1850
2.28
3.22
9.0
5.2
1.77
1.74
mu/l
0.11
197
1761
28
140
2.14
3.17
1.2
1.2
—
—
—
0
0
14
51
2.86
3.04
1.4
1.6
—
—
—
0
0
109
833
1.60
3.00
4.6
2.9
6.04
6.19
ph
0.81
54
474
13
46
2.94
2.97
3.9
1.7
7.41
7.42
ph
0.27
13
46
70
958
0.61
2.94
2.9
2.6
—
—
—
0
0
11
33
3.45
2.85
1.4
1.5
—
—
—
0
0
81
588
1.59
2.71
3.7
2.6
—
0.00
—
0
5
196
1755
1.88
2.68
8.2
4.7
39.82
37.25
mmol/mol
2.28
181
1688
34
195
1.88
2.65
1.2
1.4
—
—
—
0
0
27
143
2.01
2.64
4.3
4.8
0.00
0.31
%
—
5
32
40
242
1.79
2.64
4.9
3.5
4.74
6.14
e9/l
0.46
32
225
6
11
5.57
2.56
1.3
1.1
—
—
—
0
0
15
63
2.48
2.52
1.8
1.3
—
—
—
0
0
33
191
1.85
2.51
1.2
1.2
—
—
—
0
0
8
21
3.91
2.48
1.9
2.3
—
—
—
0
0
24
125
2.03
2.46
4.2
2.1
0.36
0.17
e6/l
0.41
24
120
127
1035
1.52
2.45
5.0
3.3
0.00
0.00
estimate
0.50
29
215
39
240
1.76
2.43
1.3
1.2
—
—
—
0
0
128
1047
1.51
2.41
5.3
3.3
0.00
0.00
estimate
-0.00
27
215
213
1977
2.35
2.41
29.4
11.7
17.21
20.24
mg/l
1.24
194
1573
26
141
1.95
2.39
1.8
2.5
1.70
1.74
%
0.10
20
131
128
1049
1.51
2.38
5.0
3.3
0.00
0.00
estimate
-0.00
29
206
22
114
2.03
2.30
2.2
2.6
1.23
1.23
mmol/l
0.10
15
105
7
18
3.98
2.27
7.1
1.3
—
—
—
0
0
18
88
2.14
2.18
1.5
2.3
7.87
6.24
ug/l
0.21
12
78
28
162
1.83
2.14
1.7
1.4
14.27
19.61
iu/l
0.54
21
133
29
170
1.81
2.13
2.2
2.5
5471.45
4215.97
u/l
—
6
80
75
561
1.50
2.12
1.7
1.3
1.44
1.89
u/ml
0.15
18
167
27
155
1.84
2.12
3.1
2.2
6.12
6.15
ph
0.05
17
97
68
499
1.52
2.10
1.8
1.3
2.25
2.22
g/l
0.05
44
327
25
415
0.55
2.09
1.8
1.5
—
—
—
0
0
5
10
5.08
2.08
1.2
1.5
3.78
10.33
ug/l
—
5
10
29
173
1.78
2.02
3.3
1.8
0.00
0.07
estimate
—
6
44
8
27
3.03
1.95
2.5
2.5
132.25
130.33
g/l
—
8
18
5
11
4.62
1.95
1.0
1.7
145.20
157.18
nmol/l
—
5
11
21
114
1.93
1.95
3.8
1.9
—
—
—
0
0
198
1820
1.71
1.91
6.9
3.9
6.06
5.67
mmol/l
2.28
187
1712
9
36
2.56
1.76
7.9
4.1
3.73
3.83
mmol/l
—
9
36
20
111
1.88
1.75
1.2
1.1
—
132.20
titre
—
0
5
7
24
2.98
1.73
1.0
1.2
—
—
—
0
0
6
19
3.21
1.67
2.2
1.4
—
—
—
0
0
6
19
3.21
1.67
2.2
1.4
—
—
—
0
0
6
19
3.21
1.67
2.2
1.4
—
—
—
0
0
6
19
3.21
1.67
2.2
1.4
—
—
—
0
0
72
559
1.42
1.63
4.6
3.3
0.00
0.00
estimate
0.50
29
212
7
160
0.42
1.61
1.3
1.8
—
—
—
0
0
7
26
2.74
1.59
1.3
1.1
—
—
—
0
0
46
330
1.49
1.56
1.5
1.4
274.29
466.67
titre
—
7
75
39
270
1.54
1.56
3.4
2.1
14.22
14.46
umol/l
0.04
39
255
58
437
1.44
1.54
1.3
1.4
80.85
29.98
iu/ml
0.32
11
136
7
27
2.64
1.52
2.3
1.3
—
—
—
0
0
54
404
1.44
1.48
1.3
1.3
0.94
9.61
u/ml
3.30
18
175
5
16
3.17
1.44
1.4
1.9
11.44
11.94
%
—
5
16
5
16
3.17
1.44
1.6
1.4
92.26
90.54
%
—
5
16
6
22
2.77
1.44
1.2
1.5
5.46
6.21
g/l
—
6
14
6
22
2.77
1.44
1.2
1.5
0.27
0.35
g/l
—
6
14
6
22
2.77
1.44
1.2
1.5
1.88
3.13
g/l
—
6
14
18
104
1.79
1.41
2.4
2.6
80.60
74.17
e9/l
—
10
73
77
620
1.37
1.38
3.4
2.0
—
—
—
0
0
6
23
2.65
1.37
1.2
1.4
—
—
—
0
0
94
783
1.34
1.35
2.1
1.9
—
—
—
0
0
17
99
1.78
1.31
2.4
2.8
—
—
—
0
0
6
24
2.54
1.31
1.2
1.5
—
—
nmol/l
—
0
0
65
515
1.37
1.28
5.8
4.2
—
—
—
0
0
21
132
1.65
1.25
1.6
1.2
—
26.19
—
0
7
13
71
1.88
1.22
1.2
1.3
—
—
—
0
0
12
64
1.92
1.20
2.4
1.5
0.17
0.40
nmol/l
—
7
54
5
20
2.53
1.15
2.6
1.4
—
—
—
0
0
5
20
2.53
1.15
1.2
1.2
—
—
—
0
0
11
58
1.94
1.14
1.6
2.0
—
—
—
0
0
8
40
2.04
1.13
1.1
1.1
—
—
—
0
0
25
169
1.54
1.13
4.2
3.3
—
—
—
0
0
7
32
2.22
1.09
1.1
1.3
208.89
42.26
mu/l
—
7
27
6
123
0.47
1.09
1.3
1.6
—
—
—
0
0
59
474
1.33
1.06
2.2
1.9
—
—
—
0
0
7
34
2.09
1.04
4.0
1.8
5.19
5.21
kpa
—
7
34
7
34
2.09
1.04
4.0
1.8
8.49
9.39
kpa
—
7
34
6
117
0.50
0.97
1.2
1.5
0.97
1.28
mm
—
6
89
6
118
0.50
0.97
1.3
1.5
—
—
—
0
0
11
62
1.81
0.96
5.9
3.5
129.80
223.24
mg/l
—
5
34
17
110
1.59
0.93
1.3
1.3
—
—
—
0
0
20
135
1.53
0.93
1.6
1.5
160.78
285.48
miu/ml
—
9
77
10
56
1.82
0.89
1.1
1.2
—
—
—
0
0
11
64
1.76
0.88
1.5
1.2
—
—
—
0
0
32
241
1.38
0.87
1.1
1.2
—
—
—
0
0
107
953
1.23
0.82
3.3
2.7
—
—
estimate
—
0
0
212
2056
1.50
0.72
34.5
13.6
70.86
71.30
umol/l
0.08
212
2031
9
58
1.57
0.70
1.4
1.1
—
—
—
0
0
11
70
1.60
0.66
1.1
1.1
—
—
—
0
0
5
30
1.68
0.62
5.6
2.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
17
228
0.72
0.58
3.0
2.4
0.71
0.73
ug/l
—
9
104
6
36
1.68
0.57
1.0
1.0
—
—
—
0
0
6
39
1.55
0.53
1.2
1.5
0.36
0.61
g/l
—
6
31
17
127
1.37
0.51
1.1
1.1
—
—
—
0
0
43
369
1.20
0.46
4.2
3.6
0.84
1.44
ug/l
3.74
37
340
65
582
1.16
0.44
2.3
1.8
—
—
—
0
0
8
57
1.42
0.42
16.8
5.6
—
—
—
0
0
5
32
1.57
0.42
1.0
1.4
4.42
6.60
pmol/l
—
5
32
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
2.7
—
39.43
—
0
6
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
0.49
—
0
18
24
200
1.22
0.35
1.4
1.3
195.36
127.94
u/ml
—
8
80
23
273
0.82
0.33
2.0
1.9
—
—
—
0
0
86
801
1.12
0.32
4.8
3.0
0.00
0.02
estimate
0.68
24
187
8
107
0.74
0.29
5.4
2.4
21.63
44.72
u/ml
—
8
102
196
1920
1.16
0.27
5.7
4.3
4.52
4.77
mmol/l
3.33
184
1837
211
2079
1.22
0.26
19.5
9.8
27.92
27.93
u/l
0.00
206
2041
16
134
1.21
0.23
1.6
1.1
—
—
—
0
0
197
1935
1.14
0.23
6.2
4.6
2.71
2.85
mmol/l
1.41
185
1847
5
39
1.29
0.23
1.2
1.1
—
—
—
0
0
5
39
1.29
0.23
5.2
4.3
4.02
4.16
e9/l
—
5
39
26
230
1.15
0.22
1.5
1.5
—
—
—
0
0
69
733
0.92
0.21
1.7
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
50
1.21
0.20
1.2
1.0
0.31
5.80
u/ml
—
6
34
6
50
1.21
0.20
4.5
3.8
65.25
59.13
%
—
6
50
8
68
1.18
0.17
2.3
1.1
—
—
—
0
0
15
131
1.16
0.15
1.4
1.4
—
—
—
0
0
66
631
1.06
0.13
4.5
2.7
0.00
0.01
estimate
0.50
21
180
183
1808
1.06
0.10
4.4
3.7
1.52
1.27
mmol/l
3.97
168
1715
193
1912
1.06
0.08
5.5
4.2
1.29
1.47
mmol/l
9.15
181
1825
180
1786
1.04
0.05
38.8
14.4
332.93
333.66
g/l
0.52
180
1778
14
148
0.94
0.02
1.4
1.1
—
—
—
0
0
208
2087
0.96
0.01
24.0
10.5
—
—
—
0
0
43
434
0.99
0.00
2.3
2.3
317.89
330.93
umol/l
0.47
36
400
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
28.83
—
0
6
0
9
0.00
0.00
0.0
1.7
—
28.33
—
0
9
0
6
0.00
0.00
0.0
1.2
—
81.32
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
6.67
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.0
—
10.49
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
11.56
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
66.09
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
11.40
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint F5_PERSOTH and mortality.

Females

Parameter HR [95% CI] p-value
F5_PERSOTH 3.96 [2.86, 5.48] < 0.001
Birth year 0.997 [0.99, 1.01] 0.546

During the follow-up period (1.1.1998 — 31.12.2019), 122 out of 874 females with F5_PERSOTH died.

Males

Parameter HR [95% CI] p-value
F5_PERSOTH 3.707 [2.77, 4.95] < 0.001
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 154 out of 864 males with F5_PERSOTH died.

Mortality risk

Mortality risk for people of age

years, who have F5_PERSOTH.

N-year risk Females Males
1 0.438% 0.701%
5 2.464% 4.344%
10 5.706% 9.585%
15 10.864% 17.3%
20 18.266% 27.732%

Relationships between endpoints

↥

Index endpoint: F5_PERSOTH – Other and unspecified disorders of adult personality and behaviour

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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