Pyoderma

L12_PYODERMA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L08.0
  • Hospital discharge: ICD-9 6860
  • Hospital discharge: ICD-8 68600
  • Cause of death: ICD-10 L08.0
  • Cause of death: ICD-9 6860
  • Cause of death: ICD-8 68600

2 out of 7 registries used, show all original rules.

827

4. Check minimum number of events

None

827

5. Include endpoints

None

827

6. Filter based on genotype QC (FinnGen only)

737

Control definitions (FinnGen only)

Control exclude
L12_INFECT_SKIN

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L08
Name in latin
Pyoderma

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7378 3141 4153
Only index persons 5683 2533 3150
Unadjusted period prevalence (%)
Whole population 0.10 0.09 0.12
Only index persons 0.11 0.09 0.12
Median age at first event (years)
Whole population 39.59 39.40 39.51
Only index persons 37.57 38.25 37.03

-FinnGen-

Key figures

All Female Male
Number of individuals 737 378 359
Unadjusted period prevalence (%) 0.15 0.13 0.16
Median age at first event (years) 44.93 42.82 47.16

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
759
Matched controls
7590
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L08.0
ICD-10 Finland
Pyoderma
1943.0
307.7
546
10
68600
ICD-8 Finland
Other local infections of skin and subcutaneous tissue, Pyoderma
+∞
179.5
165
*
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
12.5
80.8
83
74
A46
ICD-10 Finland
Erysipelas
4.5
66.2
201
564
6860A
ICD-9 Finland
Other local infections of skin and subcutaneous tissue, Pyoderma
+∞
58.1
55
*
J01FF01
ATC
clindamycin; systemic
3.3
53.4
303
1273
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
4.0
52.6
182
555
E0000UV, ,
ATC
2.9
45.5
413
2210
D07BA04
ATC
hydrocortisone and antiseptics; topical
4.3
44.8
133
360
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
12.9
44.8
44
36
L20.0
ICD-10 Finland
Besnier prurigo
4.5
43.4
119
303
TQW80
NOMESCO Finland
Local dermatologic skincare
8.5
41.4
55
69
E000001, ,
ATC
3.1
40.7
221
884
S97
ICPC
Chronic ulcer skin
4.9
40.7
96
216
D09AB01
ATC
zinc bandage without supplements; topical
10.5
37.4
42
42
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.9
36.7
228
977
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
7.5
36.0
53
75
D07AB08
ATC
desonide; topical
3.5
35.8
141
461
D07AC01
ATC
betamethasone; topical
2.5
32.5
339
1857
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.4
32.4
56
94
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.2
30.4
139
496
L30.3
ICD-10 Finland
Infective dermatitis
5.5
30.0
60
116
D07BC01
ATC
betamethasone and antiseptics; topical
3.2
29.7
136
485
D07AD01
ATC
clobetasol; topical
2.9
29.4
172
704
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
7.1
29.2
45
67
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.5
28.9
112
360
D07AC13
ATC
mometasone; topical
2.5
28.8
270
1393
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
7.4
28.2
42
60
D07CC01
ATC
betamethasone and antibiotics; topical
2.9
26.6
142
551
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.4
26.5
108
358
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
7.7
25.2
36
49
D07AA02
ATC
hydrocortisone; topical
2.8
25.1
154
642
N05BB01
ATC
hydroxyzine; systemic
3.8
24.0
79
227
D07AB02
ATC
hydrocortisone butyrate; topical
2.3
24.0
273
1509
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
23.4
403
2619
E000002, ,
ATC
3.0
23.0
117
440
R06AE07
ATC
cetirizine; oral
2.1
22.7
364
2292
E000003, ,
ATC
4.3
22.5
61
152
D06AX01
ATC
fusidic acid; topical
3.1
22.4
102
360
H02AB06
ATC
prednisolone; systemic
2.1
21.5
402
2663
J01DB01
ATC
cefalexin; oral
2.7
21.5
652
5239
-, ,
ICD-10 Finland
6.2
20.9
36
60
J01DA01
ATC
[U] cefalexin
2.1
20.2
493
3570
C03CA01
ATC
furosemide; systemic
2.1
20.0
253
1439
J01CF05
ATC
flucloxacillin; systemic
3.4
20.0
75
235
J01MA12
ATC
levofloxacin; systemic
2.4
19.9
169
816
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
6.6
19.8
32
50
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
19.6
111
441
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
7.1
19.2
29
42
D05BB02
ATC
acitretin; oral
5.6
18.7
36
67
J01DA09
ATC
[U] cefadroxil
2.1
18.5
228
1279
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
6.1
18.4
32
54
XQ802
NOMESCO Finland
Epicutan test
4.1
18.3
52
134
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
18.3
103
408
D02AX
ATC
Other emollients and protectives
4.8
17.9
41
89
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
17.9
158
774
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.1
17.6
76
259
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.7
16.7
54
153
R60.0
ICD-10 Finland
Localized oedema
2.5
16.3
115
508
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.3
16.0
42
102
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
16.0
101
423
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.4
15.6
115
518
69282
ICD-8 Finland
Other eczema and dermatitis, E microbis
20.5
15.2
22
11
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.3
15.2
127
605
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.4
15.1
118
545
D07XC01
ATC
betamethasone; topical
2.4
14.8
115
529
L03.9
ICD-10 Finland
Cellulitis, unspecified
12.2
14.7
26
22
L30.0
ICD-10 Finland
Nummular dermatitis
3.8
14.3
45
125
D02AE01
ATC
carbamide; topical
3.0
14.3
64
223
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
14.2
117
552
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.6
14.1
47
136
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.1
13.8
61
211
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.6
13.8
88
370
J01MA02
ATC
ciprofloxacin; systemic
1.8
13.7
300
2005
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
6.2
13.5
23
38
D11AX14
ATC
[U] tacrolimus
21.6
13.4
19
9
S76
ICPC
Skin infection other
3.2
13.3
54
177
N02AX02
ATC
tramadol; systemic, rectal
1.8
13.3
335
2329
D07XB05
ATC
dexamethasone; topical
4.4
13.2
33
77
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.0
13.2
190
1108
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.8
13.2
30
65
L89
ICD-10 Finland
Decubitus ulcer and pressure area
5.3
13.0
26
50
D05AX52
ATC
calcipotriol, combinations; topical
3.2
12.9
52
170
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
12.9
96
433
D01AC02
ATC
miconazole; topical
2.7
12.8
73
290
E000006, ,
ATC
2.8
12.7
66
250
NHQ40
NOMESCO Finland
Amputation of toe
6.1
12.6
22
37
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.5
12.6
44
131
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
5.8
12.5
23
41
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.7
12.4
72
288
H02AB07
ATC
prednisone; oral
2.2
12.4
116
576
S29
ICPC
Skin symptom/complaint other
2.0
12.4
163
920
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
4.2
12.2
32
78
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
12.1
211
1306
L04AX01
ATC
azathioprine; systemic
3.4
12.1
44
135
J01AA07
ATC
tetracycline; systemic
2.1
12.1
122
625
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
12.0
107
521
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
5.0
12.0
26
54
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
12.0
277
1866
S18
ICPC
Laceration/cut
1.7
12.0
356
2573
M79.6
ICD-10 Finland
Pain in limb
1.7
11.9
332
2357
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
11.8
251
1649
N06AB04
ATC
citalopram; systemic
1.9
11.7
170
991
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
3.6
11.7
39
113
SPAT1254
SPAT
Administration of medicine
2.1
11.7
118
604
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
66.0
11.6
13
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
11.5
108
536
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
11.5
136
738
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.2
11.5
46
150
SPAT1255
SPAT
Intravenous administration of medicine
2.8
11.5
59
222
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.0
11.3
52
184
ZXD05
NOMESCO Finland
Urgent procedure
1.8
11.2
232
1509
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.2
11.0
99
483
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.8
10.8
54
200
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
4.7
10.8
25
55
L28
ICPC
Limited function/disability (L)
1.9
10.8
146
830
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
28.5
10.8
14
5
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
10.6
206
1312
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
10.4
218
1417
L04AA01
ATC
[U] ciclosporin
8.4
10.4
22
27
D11AH01
ATC
tacrolimus; topical
9.7
10.3
20
21
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.9
10.3
30
79
SPAT1260
SPAT
Consultation of another employee
2.0
10.3
132
736
N03AX16
ATC
[U] pregabalin
1.8
10.1
173
1057
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.2
10.1
89
430
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.7
10.0
56
220
L20
ICD-10 Finland
Atopic dermatitis
3.5
10.0
34
100
SPAT1172
SPAT
Guidance concerning hydration
4.8
9.8
22
47
ZZA00
NOMESCO Finland
Split skin graft
3.8
9.7
29
78
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.7
9.6
30
83
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
9.6
142
828
R41.0
ICD-10 Finland
Disorientation, unspecified
3.6
9.6
31
88
L04AX03
ATC
methotrexate; systemic
2.2
9.6
83
399
L17
ICPC
Foot/toe symptom/complaint
1.7
9.5
231
1557
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
9.4
103
541
SPAT1229
SPAT
Assessment of need for aid
2.5
9.2
59
248
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
4.5
9.1
22
50
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
9.1
164
1015
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
9.1
179
1137
F05.9
ICD-10 Finland
Delirium, unspecified
4.7
9.1
21
46
AA1AD
NOMESCO Finland
CT of head and brain
1.7
9.1
211
1403
L02.0
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of face
7.2
9.1
21
30
L88
ICD-10 Finland
Pyoderma gangrenosum
37.2
9.0
11
*
SPAT1301
SPAT
No procedures
1.7
9.0
220
1482
S87
ICPC
Dermatitis/atopic eczema
3.5
9.0
30
87
UJF32
NOMESCO Finland
Coloscopy
1.7
9.0
191
1240
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
8.9
149
903
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.4
8.8
31
93
J01CE08
ATC
benzathine benzylpenicillin; parenteral
9.6
8.8
17
18
A10AE04
ATC
insulin glargine; parenteral
2.2
8.8
79
385
E66.8
ICD-10 Finland
Other obesity
2.7
8.8
46
175
A41.9
ICD-10 Finland
Sepsis, unspecified
3.2
8.7
34
109
B18.2
ICD-10 Finland
Chronic viral hepatitis C
6.7
8.7
21
32
F10.24
ICD-10 Finland
Alcohol depence active use
4.1
8.6
23
57
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
10.2
8.6
16
16
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
8.5
141
850
R50.9
ICD-10 Finland
Fever, unspecified
1.9
8.4
122
707
I50.9
ICD-10 Finland
Heart failure, unspecified
1.9
8.3
106
587
N03AX12
ATC
[U] gabapentin; oral
1.9
8.3
124
723
E66.01
ICD-10 Finland
Obesity due to excess calories
2.1
8.3
77
381
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
8.2
109
612
SPAT1216
SPAT
Assessment of functional ability
1.9
8.2
112
635
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.2
8.2
74
362
NF1AA
NOMESCO Finland
Hip X-ray examination
2.2
8.1
68
322
D11AX15
ATC
[U] pimecrolimus
33.7
8.1
10
*
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
33.7
8.1
10
*
L73.2
ICD-10 Finland
Hidradenitis suppurativa
6.4
8.1
20
32
L04AA06
ATC
mycophenolic acid; systemic
4.2
8.0
21
51
XQ800
NOMESCO Finland
Prick test
2.4
8.0
58
258
F10.20
ICD-10 Finland
Alcohol dependence currently independent
3.9
8.0
23
60
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
8.0
105
588
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
8.0
151
946
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.4
8.0
56
246
F10.25
ICD-10 Finland
Alcohol dependence continuous use
4.0
7.9
22
56
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.2
7.9
66
312
N05CD07
ATC
temazepam; oral
2.0
7.9
91
487
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
7.9
39
144
N05BA04
ATC
oxazepam; oral
1.7
7.8
189
1265
M05BA04
ATC
alendronic acid; oral
2.2
7.8
64
301
134
Kela drug reimbursment
General erythroderma
15.2
7.7
12
8
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
7.7
173
1134
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.5
7.7
26
76
69240
ICD-8 Finland
Other eczema and dermatitis, Due to other chemicals
45.4
7.7
9
*
A10AB05
ATC
insulin aspart; parenteral
2.2
7.6
62
290
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.9
7.5
35
125
N06AX11
ATC
mirtazapine; oral
1.6
7.5
245
1761
R06.0
ICD-10 Finland
Dyspnoea
1.6
7.5
201
1379
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
7.5
36
131
D07CB01
ATC
triamcinolone and antibiotics; topical
4.0
7.5
21
54
S20.2
ICD-10 Finland
Contusion of thorax
2.5
7.5
45
184
A02BC02
ATC
pantoprazole; systemic
1.5
7.4
487
4076
N05AH04
ATC
quetiapine; oral
1.8
7.3
132
814
N05AD01
ATC
haloperidol; systemic
3.2
7.3
28
89
Z3231
NOMESCO Finland
Registered nurse
1.6
7.3
193
1318
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.9
7.3
21
55
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
7.2
214
1501
N06AX21
ATC
duloxetine; oral
1.9
7.2
90
495
NG4AA
NOMESCO Finland
Lower leg X-ray examination
3.0
7.2
31
106
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
3.5
7.2
24
70
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
7.2
69
346
SPAT1263
SPAT
Sampling
1.5
7.1
288
2167
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.2
7.1
58
272
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
7.1
224
1595
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.0
7.1
31
107
L02.8
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of other sites
6.4
7.0
17
27
H02AB04
ATC
methylprednisolone; systemic
1.8
6.9
106
622
N30.0
ICD-10 Finland
Acute cystitis
1.8
6.9
119
723
T82
ICPC
Obesity
2.7
6.9
36
137
N05BA01
ATC
diazepam; systemic, rectal
1.9
6.9
97
555
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.7
6.9
37
143
J02AC01
ATC
fluconazole; systemic
1.5
6.9
263
1952
B00.10
ICD-10 Finland
Herpes simplex facialis
6.8
6.8
16
24
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
9.4
6.8
13
14
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
5.7
6.8
18
32
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
6.8
69
353
N02AA05
ATC
oxycodone; systemic
1.7
6.8
129
808
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
6.7
55
258
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.1
6.7
66
333
N05AA02
ATC
levomepromazine; systemic
2.7
6.7
35
133
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
6.7
205
1445
A04
ICPC
Weakness/tiredness general
1.8
6.7
116
706
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
6.7
70
362
R03AC02
ATC
salbutamol; inhalant
1.5
6.7
397
3222
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
2.4
6.7
43
182
N06AB03
ATC
fluoxetine; oral
1.9
6.7
93
531
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.0
6.6
29
100
TQW99
NOMESCO Finland
Other minor procedure on skin
2.5
6.6
39
158
D11AH02
ATC
pimecrolimus; topical
12.4
6.6
11
9
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.6
302
2325
P01AB01
ATC
metronidazole; oral, rectal
1.5
6.5
278
2105
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
6.9
6.5
15
22
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
6.5
47
209
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
6.5
112
682
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.6
6.5
21
60
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.6
6.5
21
60
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.5
6.5
40
166
M10.9
ICD-10 Finland
Gout, unspecified
2.2
6.4
52
243
S10
ICPC
Boil/carbuncle
2.4
6.4
45
198
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.0
6.4
28
97
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
6.3
158
1060
WX002
NOMESCO Finland
Sedation and analgesia
1.7
6.3
132
846
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
6.3
128
814
S91.3
ICD-10 Finland
Open wound of other parts of foot
3.3
6.3
23
71
A28
ICPC
Limited function/disability NOS
1.7
6.3
123
775
A06AD11
ATC
lactulose; oral
1.7
6.3
109
664
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
6.3
73
392
N05CF01
ATC
zopiclone; oral
1.5
6.3
222
1614
D05AX02
ATC
calcipotriol; topical
2.8
6.3
30
109
T78.4
ICD-10 Finland
Allergy, unspecified
2.6
6.3
35
138
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
6.3
78
429
N07BA03
ATC
varenicline; oral
2.4
6.2
40
169
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
6.2
76
415
L04AD01
ATC
ciclosporin; systemic
3.7
6.2
19
52
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.0
6.2
27
93
SPAT1210
SPAT
Application of cast or individual aid
2.7
6.2
33
127
Z2446
NOMESCO Finland
Social worker
2.2
6.2
53
254
A10BB12
ATC
glimepiride; oral
2.2
6.2
53
254
J01FA01
ATC
erythromycin; systemic
1.8
6.2
91
528
R06AX13
ATC
loratadine; oral
1.8
6.2
105
636
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
6.2
240
1780
R06AX22
ATC
ebastine; oral
1.7
6.2
120
755
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
6.1
290
2237
N03AE01
ATC
clonazepam; systemic
2.4
6.1
42
183
J01FA06
ATC
roxithromycin; oral
1.5
6.1
274
2091
127
Kela drug reimbursment
Transplant complication
4.2
6.1
16
39
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
6.1
71
382
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
6.1
74
404
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
6.8
6.1
14
21
J04BA02
ATC
dapsone; oral
10.1
6.0
11
11
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.9
6.0
78
434
R06AE09
ATC
levocetirizine; oral
1.8
6.0
101
609
205
Kela drug reimbursment
Chronic hypertension
1.6
6.0
177
1234
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
6.0
306
2393
J01MA14
ATC
moxifloxacin; systemic
2.0
6.0
68
362

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
196
684
3.51
45.78
2.9
1.6
—
—
—
0
0
304
1702
2.31
26.43
5.7
4.1
—
—
—
0
0
178
867
2.38
20.64
2.7
1.9
—
—
—
0
0
408
2878
1.90
16.63
10.5
6.7
1.21
1.21
mmol/l
0.01
375
2655
436
3218
1.83
14.65
10.4
7.3
1.21
1.21
mmol/l
0.31
380
2789
393
2815
1.82
14.53
7.2
5.1
35.43
35.92
g/l
0.90
365
2644
320
2181
1.81
13.72
9.3
6.4
—
—
—
0
0
169
957
1.99
12.77
3.2
2.5
2.34
2.32
g/l
0.16
150
892
69
269
2.72
12.53
1.3
1.3
—
—
—
0
0
150
820
2.03
12.49
1.7
1.4
—
—
—
0
0
180
1050
1.94
12.44
3.2
2.5
11.70
13.63
umol/l
2.96
161
985
445
3400
1.75
12.39
7.6
6.7
10.37
11.83
umol/l
1.45
426
3243
437
3331
1.74
12.18
9.8
6.3
0.62
0.58
e9/l
2.21
371
2872
449
3449
1.74
12.17
10.0
6.6
0.21
0.19
e9/l
1.51
382
3025
437
3337
1.73
12.05
9.8
6.3
0.04
0.04
e9/l
1.43
372
2877
157
891
1.96
11.70
3.2
2.5
20.73
23.57
%
1.91
142
837
182
1089
1.88
11.56
4.7
3.8
0.80
0.82
mmol/l
1.88
171
1023
439
3386
1.70
11.39
10.0
6.4
1.89
1.93
e9/l
0.24
388
2999
470
3703
1.71
11.17
13.4
9.6
4.45
4.07
e9/l
2.76
401
3240
473
3744
1.70
10.94
8.0
5.2
6.82
6.62
mmol/l
1.03
458
3537
133
735
1.98
10.63
8.9
8.3
5.23
5.07
kpa
0.88
124
707
133
735
1.98
10.63
8.9
8.3
11.66
12.21
kpa
0.76
126
710
268
1852
1.69
10.21
3.7
2.9
—
—
—
0
0
149
869
1.89
10.12
9.8
6.2
1.06
1.05
mmol/l
0.25
141
804
131
732
1.95
10.12
9.3
8.4
7.42
7.41
ph
0.24
78
424
177
1095
1.80
9.94
3.4
2.8
1.20
0.90
e6/l
0.82
101
583
115
620
2.01
9.83
2.6
2.4
0.20
0.21
g/l
0.76
107
579
273
1912
1.67
9.80
6.6
4.1
7.40
7.40
ph
0.01
206
1364
276
1944
1.66
9.66
2.5
2.1
152.74
265.40
u/l
1.44
255
1846
243
1665
1.68
9.41
3.3
2.1
2.95
2.84
mg/l
0.27
207
1432
382
2932
1.61
9.37
19.0
12.9
1.25
1.24
inr
0.14
334
2444
147
874
1.85
9.35
10.9
6.7
104.05
104.26
mmol/l
0.21
147
874
128
729
1.91
9.30
9.0
8.3
0.56
0.86
mmol/l
0.39
104
595
397
3080
1.61
9.27
10.5
6.5
8.82
8.91
%
0.21
369
2897
163
1009
1.78
9.06
1.8
1.7
1227.12
1172.69
nmol/l
0.29
123
771
395
3083
1.59
8.83
10.2
6.3
58.72
57.07
%
1.76
372
2954
570
4876
1.68
8.57
11.4
8.1
78.03
79.90
u/l
0.57
543
4642
400
3145
1.57
8.57
10.4
6.4
26.11
27.85
%
2.17
376
2988
95
505
2.01
8.41
2.6
2.3
4.14
8.49
ug/l
3.01
81
445
360
2774
1.57
8.35
2.6
2.1
90.43
95.34
pmol/l
1.39
189
1473
112
632
1.91
8.34
8.1
4.1
2.20
1.72
mmol/l
0.79
103
533
391
3073
1.56
8.28
10.5
6.4
2.88
2.91
%
0.10
362
2887
137
828
1.80
8.20
3.0
2.5
133.50
112.32
ug/g
0.48
107
665
279
2039
1.58
8.08
3.6
2.5
52.03
63.93
u/l
2.71
258
1903
59
269
2.29
7.72
7.7
5.7
25.59
24.95
mmol/l
0.60
53
250
259
1879
1.57
7.65
4.2
3.2
1894.79
1194.33
ng/l
1.06
219
1606
30
97
3.18
7.63
4.8
1.6
—
—
—
0
0
387
3071
1.53
7.61
10.7
6.5
0.69
0.69
%
0.03
359
2881
97
539
1.92
7.55
3.4
3.1
69.84
70.04
e9/l
0.02
77
403
101
571
1.89
7.46
2.6
2.1
0.00
0.04
estimate
0.78
19
117
227
1606
1.59
7.43
6.0
4.3
90.30
89.97
%
0.07
221
1577
66
322
2.15
7.34
7.4
5.2
—
—
—
0
0
206
1435
1.60
7.16
2.1
1.9
0.85
1.13
mg/l
1.85
153
1125
56
258
2.26
7.16
2.3
1.8
2.83
2.45
ug/l
0.07
47
226
157
1022
1.68
7.16
3.5
3.0
3.25
1.92
e6/l
0.69
82
509
87
479
1.92
6.95
5.0
4.1
96.77
80.06
ng/l
0.75
73
421
246
1796
1.55
6.94
4.4
3.1
0.99
0.40
e6/l
1.16
181
1316
83
450
1.95
6.94
7.7
4.9
7.42
7.42
ph
0.27
70
370
110
663
1.77
6.59
8.4
4.0
7.38
7.38
ph
0.12
69
382
357
2848
1.48
6.47
3.3
2.5
74.91
76.76
nmol/l
0.52
315
2574
40
166
2.49
6.46
1.2
1.1
—
—
—
0
0
292
2238
1.50
6.46
4.2
3.4
29.72
32.44
u/l
0.92
272
2132
38
154
2.54
6.45
2.6
3.1
33.73
34.78
umol/l
0.09
33
139
215
1546
1.55
6.42
3.1
2.3
—
—
—
0
0
40
170
2.43
6.16
4.5
1.8
—
—
—
0
0
69
366
1.97
6.15
4.2
5.7
—
—
—
0
0
309
2419
1.47
6.04
4.7
3.6
26.69
38.24
ng/l
2.01
209
1695
286
2207
1.47
6.01
4.0
3.3
7.83
7.92
mmol/l
0.10
234
1877
113
709
1.70
5.86
3.6
2.9
1.80
1.78
%
0.08
98
646
15
26
5.86
5.86
1.0
1.1
306.63
137.80
iu/ml
1.51
15
26
105
647
1.72
5.81
3.1
2.1
379.52
379.93
nmol/l
0.01
98
609
193
2587
0.66
5.77
3.1
3.0
—
—
—
0
0
376
3079
1.44
5.68
3.7
3.0
130.51
122.51
ug/l
0.20
347
2898
43
196
2.27
5.68
3.7
1.5
—
—
—
0
0
252
1920
1.47
5.56
8.4
6.2
—
—
—
0
0
120
776
1.65
5.54
2.0
1.6
—
—
—
0
0
85
502
1.78
5.45
1.8
1.5
—
—
—
0
0
96
589
1.72
5.39
3.4
2.4
29.29
35.86
u/l
1.34
85
499
87
519
1.76
5.39
2.8
3.1
66.77
66.97
g/l
0.09
74
479
350
2850
1.42
5.35
16.1
11.2
0.00
0.00
e9/l
0.20
284
2346
61
327
1.94
5.30
1.4
1.2
—
—
—
0
0
241
1836
1.46
5.27
2.0
1.7
19.47
20.29
nmol/l
0.38
195
1551
91
554
1.73
5.26
4.3
4.2
7.38
7.35
ph
0.84
59
395
266
2070
1.44
5.18
3.2
2.4
—
—
—
0
0
270
2107
1.44
5.18
4.7
3.2
34.04
84.04
e6/l
0.84
201
1619
221
1661
1.47
5.17
4.0
2.8
345.17
344.98
umol/l
0.01
190
1495
91
558
1.72
5.12
15.9
8.9
—
—
—
0
0
277
2177
1.43
5.09
4.1
3.5
2.37
2.35
mmol/l
0.86
246
1986
503
4394
1.43
5.03
5.9
4.4
—
2.63
—
0
8
68
389
1.82
4.85
11.5
9.6
23.98
24.17
mmol/l
0.19
62
383
260
2046
1.41
4.66
3.9
3.4
45.39
52.11
mg/l
0.22
177
1323
139
969
1.53
4.65
2.8
2.6
30.12
29.50
s
0.52
133
949
50
265
1.95
4.51
1.8
2.0
1.66
1.47
g/l
0.63
43
240
168
1241
1.45
4.21
2.9
3.0
2.46
2.45
mmol/l
0.48
150
1120
355
2984
1.36
4.12
3.4
2.8
—
—
estimate
—
0
0
118
815
1.53
4.11
5.2
2.9
4.74
5.55
e9/l
0.38
97
714
260
2084
1.38
4.07
4.6
4.1
7.77
9.56
mg/mmol
0.32
164
1303
402
3452
1.35
4.03
4.9
3.8
0.01
0.46
estimate
0.50
69
667
43
226
1.96
4.00
1.3
1.3
—
—
—
0
0
294
2415
1.35
3.91
5.4
3.8
123.87
90.60
e6/l
0.17
204
1697
327
2730
1.35
3.91
4.5
3.4
6.37
6.19
ph
1.99
168
1587
82
528
1.62
3.86
1.3
1.2
—
—
—
0
0
394
3388
1.34
3.84
4.9
3.7
0.00
0.00
estimate
-0.00
76
695
139
1009
1.46
3.79
1.9
1.7
—
—
—
0
0
18
66
2.77
3.77
2.0
1.6
229.44
311.87
mu/l
—
9
53
43
232
1.90
3.72
2.0
2.7
—
—
—
0
0
178
1358
1.41
3.70
1.5
1.5
2.58
2.43
g/l
0.50
96
841
52
299
1.79
3.69
2.3
2.2
0.00
0.01
estimate
0.50
16
96
122
872
1.48
3.60
1.4
1.2
—
—
—
0
0
234
1875
1.36
3.60
5.4
3.8
0.00
0.01
estimate
0.96
74
651
396
3429
1.32
3.58
4.9
3.8
17.41
7.11
estimate
0.25
78
708
43
236
1.87
3.55
4.0
1.5
—
—
—
0
0
198
1554
1.37
3.45
1.4
1.3
1.51
1.80
u/ml
0.14
41
434
85
569
1.56
3.41
5.8
4.7
0.69
1.01
%
0.82
39
184
72
464
1.61
3.39
1.5
1.2
1745.44
246.75
u/ml
1.05
66
428
540
4908
1.35
3.39
4.7
4.1
14.71
14.71
pmol/l
0.00
491
4520
62
386
1.66
3.35
7.3
3.6
125.42
129.88
g/l
0.90
62
375
28
135
2.12
3.32
3.6
1.6
0.80
0.85
nmol/l
0.15
21
115
66
421
1.62
3.25
2.3
2.6
—
—
—
0
0
10
24
4.21
3.20
2.8
1.9
—
—
—
0
0
42
239
1.80
3.12
5.0
3.5
295.17
246.44
mg/l
0.19
24
108
51
308
1.70
3.10
1.6
1.7
0.29
0.39
mg/l
0.41
23
147
22
99
2.26
3.08
1.7
1.4
—
—
—
0
0
14
52
2.72
2.90
2.6
3.0
37.00
40.66
%
—
8
29
27
136
2.02
2.88
1.5
1.6
—
—
—
0
0
79
542
1.51
2.86
6.0
4.8
0.09
0.13
%
0.38
35
158
660
6246
1.43
2.85
27.8
15.0
26.54
24.00
mg/l
1.17
586
5080
182
1450
1.34
2.83
3.9
2.5
8.61
5.41
e6/l
0.74
163
1321
146
1125
1.37
2.82
1.4
1.3
15.48
14.46
u/ml
0.05
59
440
42
247
1.74
2.82
4.1
1.5
—
—
—
0
0
8
18
4.48
2.80
1.0
1.2
—
—
—
0
0
42
248
1.73
2.78
4.1
1.5
—
—
—
0
0
5
6
8.38
2.75
1.0
1.3
—
—
—
0
0
42
249
1.73
2.75
4.2
1.4
—
—
—
0
0
28
147
1.94
2.68
1.5
1.2
—
—
—
0
0
78
543
1.49
2.65
5.9
4.5
1.57
0.60
%
0.73
35
167
12
41
2.96
2.63
1.5
1.4
152.75
150.67
nmol/l
0.03
12
41
34
192
1.81
2.62
1.4
1.4
218.96
298.16
ug/g
0.96
18
117
17
74
2.33
2.59
4.9
4.3
—
—
—
0
0
37
216
1.75
2.57
2.0
2.4
10.05
10.82
g/l
0.35
28
199
10
31
3.25
2.52
1.0
1.7
67.40
60.84
umol/l
—
5
19
17
76
2.27
2.45
4.4
2.4
32.41
33.53
pg
0.53
17
76
75
527
1.47
2.44
2.5
2.9
10.49
10.57
g/l
0.06
64
488
17
77
2.24
2.39
3.3
1.9
10.86
10.36
mmol/l
0.27
17
77
7
17
4.15
2.36
1.1
2.2
—
—
—
0
0
481
4401
1.25
2.34
4.9
3.3
52.90
48.31
u/l
0.53
455
4161
121
933
1.35
2.33
1.5
1.3
673.10
531.18
titre
0.40
29
204
98
736
1.38
2.23
3.8
3.1
8.45
8.46
umol/l
0.00
83
659
13
54
2.43
2.20
1.7
1.4
2.03
1.13
promille
—
7
47
15
67
2.26
2.18
1.3
1.1
—
—
—
0
0
15
67
2.26
2.18
1.3
1.1
—
—
—
0
0
18
87
2.09
2.18
4.6
5.7
368.44
364.38
umol/l
0.04
18
77
20
101
2.01
2.17
1.5
1.4
37.24
23.67
u/l
0.72
14
85
32
189
1.72
2.17
1.3
1.2
2.98
10.88
u/ml
—
8
32
152
1225
1.30
2.16
2.5
1.9
—
—
—
0
0
7
19
3.71
2.15
4.3
3.3
—
37.30
—
0
5
24
130
1.87
2.14
1.1
1.6
—
—
—
0
0
67
474
1.45
2.13
2.7
3.5
185.28
191.91
ng/l
0.05
57
439
76
552
1.42
2.10
6.3
5.0
0.17
0.20
%
0.07
29
143
42
630
0.65
2.03
1.4
1.4
—
—
—
0
0
665
6375
1.35
1.99
31.1
17.7
3.97
3.97
mmol/l
0.11
647
6238
39
250
1.59
1.96
4.3
1.5
—
—
—
0
0
37
235
1.60
1.94
1.5
1.3
154.32
253.28
miu/ml
0.91
11
113
9
33
2.75
1.93
3.3
2.3
—
—
—
0
0
150
1225
1.28
1.92
1.4
1.3
38.46
35.33
iu/ml
0.10
44
374
42
276
1.55
1.91
2.2
2.0
9.21
9.20
iu/ml
0.00
13
64
614
5831
1.28
1.91
6.2
5.1
1.90
1.90
mu/l
0.01
566
5401
31
189
1.67
1.90
1.3
1.2
2.32
2.78
u/ml
—
5
22
21
114
1.87
1.89
1.2
1.1
—
—
—
0
0
663
6366
1.33
1.85
30.9
17.6
139.37
139.69
mmol/l
2.88
647
6241
20
108
1.87
1.83
1.2
1.1
—
—
—
0
0
14
66
2.14
1.83
1.0
1.6
—
—
—
0
0
179
1504
1.25
1.81
6.8
4.6
—
—
—
0
0
25
146
1.74
1.79
1.3
1.5
1.65
17.88
e6/l
1.60
17
109
5
134
0.37
1.77
1.6
1.6
—
—
—
0
0
6
18
3.35
1.75
1.3
1.3
28.83
47.75
%
—
6
12
6
18
3.35
1.75
1.2
1.3
2.50
1.28
%
—
6
13
33
210
1.60
1.73
10.2
5.1
1.65
1.51
mg/l
0.28
28
190
8
30
2.68
1.72
1.4
1.7
—
—
—
0
0
5
13
3.86
1.71
4.2
1.4
1.26
1.40
umol/l
—
5
7
151
1254
1.25
1.69
3.8
2.7
539.72
544.78
mosm/kgh2o
0.10
131
1096
25
149
1.70
1.68
1.4
1.6
40.72
116.37
e6/l
0.78
18
115
31
196
1.61
1.68
4.5
7.9
1.24
1.32
mmol/l
0.25
26
175
36
531
0.66
1.64
1.4
1.8
3.58
3.45
mmol/l
0.22
21
381
97
765
1.31
1.63
1.5
1.4
—
—
—
0
0
24
143
1.70
1.63
3.0
2.3
135.96
118.91
ug/min
0.09
15
82
5
14
3.59
1.62
2.0
1.7
—
—
—
0
0
20
113
1.79
1.61
12.5
3.9
2.61
2.58
mmol/l
0.02
15
74
25
151
1.68
1.61
1.4
1.6
—
—
—
0
0
37
247
1.52
1.60
3.6
2.8
21.81
21.00
s
0.48
31
227
19
106
1.81
1.60
1.6
1.2
6.80
8.08
u/ml
—
10
49
34
223
1.55
1.59
1.8
1.4
—
—
—
0
0
82
634
1.33
1.59
1.7
1.7
—
—
—
0
0
163
1913
0.81
1.58
4.0
3.2
0.02
0.05
estimate
0.33
60
560
148
1237
1.24
1.57
5.3
3.8
38.33
489.57
ng/l
6.24
115
948
15
78
1.94
1.55
1.5
1.4
18.08
27.04
ng/l
0.86
15
78
281
2506
1.19
1.55
2.2
2.1
—
—
—
0
0
7
27
2.61
1.51
1.1
1.1
—
—
—
0
0
86
681
1.30
1.42
1.5
1.5
—
—
—
0
0
24
153
1.59
1.30
1.5
1.7
—
—
—
0
0
22
336
0.64
1.23
1.9
1.7
—
—
—
0
0
611
5878
1.20
1.22
8.0
6.1
40.70
38.97
mmol/mol
3.75
563
5536
11
56
1.98
1.22
1.3
3.1
761.73
1103.80
e6/l
1.31
11
46
14
78
1.81
1.21
1.8
1.2
—
—
—
0
0
55
420
1.33
1.20
1.7
1.7
0.90
1.52
g/l
2.72
49
392
8
38
2.12
1.18
5.0
1.4
13.43
22.75
umol/l
—
8
33
24
158
1.54
1.16
2.1
1.6
20256.50
12661.83
e6/l
0.32
18
119
19
118
1.63
1.15
1.8
1.2
—
—
—
0
0
12
65
1.86
1.14
2.6
2.6
—
—
—
0
0
60
469
1.30
1.13
10.9
4.1
1.23
1.23
mmol/l
0.15
54
400
7
30
2.35
1.12
6.6
1.5
2.11
1.90
umol/l
—
7
24
11
58
1.91
1.12
1.1
1.1
—
—
—
0
0
32
226
1.43
1.11
2.1
2.1
17577.25
5740.75
u/l
—
10
100
13
73
1.79
1.11
2.8
2.4
—
—
—
0
0
7
31
2.27
1.10
1.0
1.4
124.71
181.70
mmol/24h
—
7
31
18
112
1.62
1.09
3.6
3.2
3.20
4.16
e9/l
1.87
18
112
37
270
1.39
1.08
1.3
1.2
0.30
1.76
u/ml
—
5
17
10
52
1.94
1.06
2.3
3.3
38.45
36.76
%
—
10
52
12
67
1.80
1.05
1.7
5.3
11.87
10.80
%
0.33
12
67
15
90
1.68
1.04
4.2
2.9
—
—
—
0
0
21
138
1.54
1.04
1.5
1.6
162.86
150.40
au/ml
—
7
41
76
621
1.25
1.02
3.7
4.7
7.51
27.67
ug/l
0.85
56
513
5
23
2.18
0.98
3.4
3.7
—
—
—
0
0
16
247
0.64
0.97
1.2
1.2
0.84
0.90
g/l
0.40
16
247
15
235
0.63
0.97
1.1
1.1
1.46
1.55
g/l
0.54
15
235
18
116
1.57
0.97
5.8
1.3
62.92
62.96
mmol/l
0.00
12
102
7
36
1.95
0.97
5.0
3.7
13.70
17.25
%
—
7
36
0
31
0.00
0.96
0.0
9.5
—
499.65
—
0
23
11
62
1.79
0.94
1.2
1.4
—
—
—
0
0
66
537
1.25
0.93
1.5
1.4
—
—
—
0
0
11
184
0.59
0.93
1.2
1.1
—
—
—
0
0
6
27
2.23
0.93
3.5
2.3
61.00
50.32
umol/l
—
6
22
118
1358
0.84
0.93
3.4
3.2
0.62
0.79
ug/l
2.55
74
870
15
94
1.61
0.91
1.1
1.2
—
—
—
0
0
17
111
1.54
0.88
1.0
1.6
0.73
0.74
g/l
0.01
12
92
15
95
1.59
0.88
2.1
1.7
—
—
—
0
0
15
95
1.59
0.88
2.1
1.7
—
—
—
0
0
15
95
1.59
0.88
2.1
1.7
—
—
—
0
0
15
95
1.59
0.88
2.1
1.7
—
—
—
0
0
171
1536
1.15
0.83
6.0
3.9
1.02
1.02
kg/l
0.04
117
1048
17
113
1.52
0.82
8.6
3.3
7.05
8.86
pmol/l
0.50
17
113
8
46
1.75
0.82
1.4
3.5
175.75
215.62
e6/l
—
8
37
15
224
0.66
0.81
1.1
1.1
—
0.71
—
0
25
8
47
1.71
0.81
1.1
1.0
—
—
—
0
0
23
164
1.42
0.80
3.5
3.0
0.47
2.10
index
1.93
15
95
16
106
1.52
0.79
2.1
2.5
—
—
—
0
0
13
82
1.60
0.78
1.1
1.2
—
—
—
0
0
15
99
1.53
0.76
1.1
1.1
2.38
7.99
u/ml
—
9
39
7
38
1.85
0.73
1.0
1.2
5.77
6.64
ug/l
—
7
33
18
125
1.45
0.73
5.2
3.6
—
—
—
0
0
5
26
1.93
0.70
4.0
3.5
—
—
—
0
0
676
6635
1.17
0.68
32.4
19.4
78.51
77.35
umol/l
0.34
662
6563
5
28
1.79
0.66
2.0
1.1
—
—
—
0
0
12
78
1.55
0.66
2.3
2.6
—
50.29
—
0
8
20
146
1.38
0.64
2.2
1.4
254.08
247.39
u/ml
0.03
13
83
5
29
1.73
0.64
4.0
3.2
—
—
—
0
0
5
29
1.73
0.64
1.0
1.1
1656.60
1717.31
miu/ml
—
5
29
34
270
1.27
0.63
2.8
1.8
—
—
—
0
0
659
6464
1.15
0.62
22.2
13.6
—
—
—
0
0
460
4427
1.10
0.62
4.6
3.9
0.50
8418.25
—
6
12
28
356
0.78
0.61
1.1
1.1
—
—
—
0
0
19
139
1.38
0.61
1.2
1.1
2.58
2.60
u/ml
0.00
14
73
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
6
35
1.72
0.57
8.0
1.4
31.17
28.83
umol/l
—
6
30
16
115
1.40
0.57
1.1
1.0
0.47
4.90
u/ml
—
8
61
11
73
1.51
0.56
1.2
1.3
—
—
—
0
0
31
248
1.26
0.56
1.1
1.1
—
—
—
0
0
6
37
1.63
0.55
15.8
12.5
0.58
0.67
mmol/l
—
6
37
9
61
1.48
0.54
2.2
1.2
—
—
—
0
0
21
161
1.31
0.52
6.0
2.9
1.45
1.61
mmol/l
0.56
21
156
139
1273
1.11
0.52
1.6
1.7
480.96
27002295.24
pmol/l
1.21
115
1074
209
2229
0.91
0.51
5.3
5.5
1.90
2.61
ug/l
1.64
179
2032
6
41
1.47
0.50
5.8
3.4
6.15
7.93
mmol/l
—
6
41
518
5312
0.92
0.47
34.8
19.3
330.83
332.82
g/l
5.22
513
5281
283
2693
1.08
0.47
2.1
1.9
1.49
1.36
mmol/l
1.78
240
2301
15
112
1.35
0.45
1.1
1.0
0.55
0.44
u/ml
—
9
47
66
744
0.88
0.45
1.8
1.6
—
—
—
0
0
39
330
1.19
0.45
1.5
1.3
34.85
26.09
iu/l
0.77
33
276
29
239
1.22
0.43
1.3
1.6
19.22
8.75
u/ml
—
5
48
5
32
1.57
0.42
1.4
2.3
13.68
7.52
nmol/l
—
5
26
10
70
1.43
0.42
2.1
1.3
—
—
—
0
0
5
33
1.52
0.41
1.8
1.5
—
—
—
0
0
5
34
1.47
0.40
1.4
1.1
7.40
7.37
ph
—
5
25
0
18
0.00
0.40
0.0
1.1
—
51.15
—
0
18
22
178
1.24
0.39
1.1
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
14.89
—
0
14
667
6588
1.10
0.36
18.0
11.8
26.72
26.62
u/l
0.06
647
6422
179
1893
0.93
0.36
1.4
1.4
—
—
—
0
0
19
153
1.25
0.35
3.8
3.0
51.99
58.07
%
1.11
19
153
6
43
1.40
0.35
1.2
1.2
—
—
—
0
0
6
47
1.28
0.32
1.2
1.1
96.17
102.36
pmol/l
—
6
47
23
273
0.84
0.32
1.6
1.6
878.15
1004.13
mu/l
0.36
17
228
19
156
1.22
0.31
2.7
2.3
139.58
131.98
g/l
0.71
12
124
10
75
1.34
0.30
1.1
1.9
—
—
—
0
0
67
614
1.10
0.28
2.6
2.3
12.93
12.95
nmol/l
0.01
59
565
8
62
1.29
0.28
1.0
1.3
—
—
—
0
0
596
5880
1.06
0.27
5.0
4.2
1.36
1.28
mmol/l
1.78
548
5456
12
149
0.80
0.26
4.3
4.4
—
—
—
0
0
9
74
1.22
0.25
1.2
1.1
—
—
—
0
0
43
388
1.11
0.25
3.9
3.6
4.53
4.63
pmol/l
0.22
38
346
9
76
1.19
0.24
1.1
1.3
—
—
nmol/l
—
0
0
269
2611
1.05
0.23
5.0
3.6
0.05
0.02
estimate
0.24
59
590
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
9.87
—
0
13
33
298
1.11
0.19
3.1
2.4
—
—
—
0
0
7
58
1.21
0.18
2.1
2.8
—
—
—
0
0
12
100
1.20
0.18
2.8
2.1
—
—
—
0
0
11
129
0.85
0.15
1.7
1.6
—
—
—
0
0
12
103
1.17
0.14
1.3
1.4
0.13
0.36
nmol/l
—
7
79
87
835
1.05
0.13
1.3
1.3
—
—
—
0
0
606
6020
1.03
0.11
6.3
5.0
6.19
5.91
mmol/l
3.48
555
5551
11
126
0.87
0.11
1.6
1.4
—
—
—
0
0
681
6839
0.96
0.10
40.4
23.1
132.05
135.96
g/l
8.86
670
6771
11
96
1.15
0.10
1.5
1.9
—
—
—
0
0
681
6837
0.96
0.09
39.7
22.9
7.14
6.71
e9/l
5.59
660
6682
681
6837
0.96
0.09
39.6
22.8
30.17
30.33
pg
1.42
669
6769
681
6837
0.96
0.09
39.7
22.9
4.41
4.51
e12/l
6.01
662
6688
681
6837
0.96
0.09
40.7
23.4
39.61
41.21
%
1.67
669
6765
681
6835
0.96
0.09
39.6
22.9
91.09
90.96
fl
0.30
669
6768
6
56
1.07
0.08
1.2
1.1
—
—
—
0
0
6
58
1.03
0.08
1.5
1.1
—
—
—
0
0
681
6834
0.97
0.08
39.6
22.9
256.40
249.06
e9/l
1.80
663
6702
5
64
0.78
0.08
1.0
1.4
270.40
282.82
mosm/kgh2o
—
5
49
616
6189
0.98
0.08
6.0
5.0
4.42
4.62
mmol/l
5.09
569
5809
7
64
1.09
0.08
1.3
1.8
—
—
—
0
0
46
480
0.96
0.08
1.3
1.2
42.64
152.82
u/ml
4.94
16
197
7
66
1.06
0.08
3.6
2.3
—
—
—
0
0
7
67
1.05
0.08
1.1
1.5
—
—
—
0
0
8
91
0.88
0.06
1.3
1.1
—
—
—
0
0
50
517
0.96
0.06
5.2
3.6
—
—
—
0
0
625
6267
0.98
0.04
6.6
5.7
2.58
2.71
mmol/l
3.17
582
5861
14
149
0.94
0.03
1.1
1.3
—
—
—
0
0
22
211
1.04
0.03
1.9
1.4
11.97
9.27
u/l
0.27
16
169
14
148
0.94
0.02
1.3
1.2
—
—
—
0
0
615
6162
0.99
0.02
5.8
4.9
1.38
1.45
mmol/l
4.13
566
5747
19
182
1.05
0.02
16.7
9.4
—
—
—
0
0
44
447
0.98
0.01
1.3
1.2
—
—
—
0
0
10
103
0.97
0.00
1.1
1.2
—
—
—
0
0
17
173
0.98
0.00
2.0
2.0
3.40
4.47
iu/l
—
5
66
51
515
0.99
0.00
3.2
2.3
6.03
6.08
ph
0.18
37
347
71
714
0.99
0.00
1.5
1.5
—
—
—
0
0
13
129
1.01
0.00
1.0
1.1
—
—
—
0
0
13
129
1.01
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
3.8
—
45.40
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
7.6
—
8.60
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
80.83
—
0
6
0
9
0.00
-0.00
0.0
9.6
—
0.32
—
0
9
6
69
0.87
-0.00
2.0
2.3
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.1
—
—
—
0
0
7
77
0.91
-0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
70.43
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
1.81
—
0
7

Mortality – FinRegistry

Association

Association between endpoint L12_PYODERMA and mortality.

Females

Parameter HR [95% CI] p-value
L12_PYODERMA 2.971 [2.44, 3.62] < 0.001
Birth year 0.996 [0.99, 1.01] 0.409

During the follow-up period (1.1.1998 — 31.12.2019), 506 out of 2065 females with L12_PYODERMA died.

Males

Parameter HR [95% CI] p-value
L12_PYODERMA 3.025 [2.54, 3.61] < 0.001
Birth year 0.989 [0.98, 1.0] 0.028

During the follow-up period (1.1.1998 — 31.12.2019), 688 out of 2431 males with L12_PYODERMA died.

Mortality risk

Mortality risk for people of age

years, who have L12_PYODERMA.

N-year risk Females Males
1 0.308% 0.658%
5 1.762% 3.384%
10 4.729% 8.653%
15 8.484% 16.462%
20 14.789% 26.195%

Relationships between endpoints

Index endpoint: L12_PYODERMA – Pyoderma

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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