This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
ILD medications: pirfenidone
ILD_PIRFENIDONE
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
441 |
4. Check minimum number of events
Min. number of events
3
|
441 |
5. Include endpointsNone |
441 |
6. Filter based on genotype QC (FinnGen only) |
367 |
Control definitions (FinnGen only)
- Control exclude
- ILD_MEDICATIONS
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
ILD medications: pirfenidone
based on the number of shared cases.
Similar with more cases:
- ILD, hospital admissions
- Interstitial lung disease endpoints
- Other interstitial pulmonary diseases
- Interstitial lung disease
- Respiratory diseases principally affecting the interstitium, IBD co-morbidites
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 367 | 102 | 265 |
| Unadjusted period prevalence (%) | 0.10 | 0.04 | 0.12 |
| Median age at first event (years) | 72.74 | 71.87 | 73.07 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 379
- Matched controls
- 3790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L04AX05
ATC
pirfenidone; oral
+∞
307.7
379
*
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
203.6
307.7
225
27
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
7803.2
307.7
371
26
356
Kela drug reimbursment
Nintedanib and pirfenidone
13909.2
307.7
338
*
284
Kela drug reimbursment
Nintedanib and pirfenidone
4503599627370496.0
307.7
366
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
46.3
287.4
193
83
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
32.8
182.4
128
58
TGC00
NOMESCO Finland
Bronchial lavation
34.4
143.5
96
37
UGC12
NOMESCO Finland
Flexible bronchoscopy
15.3
136.5
146
149
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
27.9
127.7
92
43
XG410
NOMESCO Finland
Flow-volume spirometry
19.5
103.3
87
57
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
55.7
99.1
57
12
H02AB06
ATC
prednisolone; systemic
9.5
98.6
279
860
L01XE31
ATC
[U] nintedanib
+∞
88.0
81
*
GD1AD
NOMESCO Finland
Thorax CT examination
10.4
85.6
113
149
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
12.7
82.4
90
91
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
20.3
81.8
66
39
L01EX09
ATC
nintedanib; oral
189.3
75.1
76
5
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
7.1
66.5
129
258
J96.1
ICD-10 Finland
Chronic respiratory failure
19.1
64.6
53
32
GD1AA
NOMESCO Finland
Thorax X-ray examination
8.4
57.8
327
1621
R03AC02
ATC
salbutamol; inhalant
5.8
54.4
284
1287
N02AA01
ATC
morphine; systemic, rectal
15.5
53.7
49
36
Z51.5
ICD-10 Finland
Palliative care
5.6
49.0
119
287
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
7.2
49.0
84
145
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
165.4
42.7
44
*
R06.0
ICD-10 Finland
Dyspnoea
4.2
41.8
189
728
L04AA06
ATC
mycophenolic acid; systemic
+∞
39.3
37
*
R99
ICPC
Respiratory disease other
12.7
38.4
39
34
R03BA08
ATC
ciclesonide; inhalant
6.9
38.4
66
113
R05
ICD-10 Finland
Cough
4.2
37.8
141
468
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
108.4
36.5
39
*
127
Kela drug reimbursment
Transplant complication
+∞
36.0
34
*
Z94.2
ICD-10 Finland
Lung transplant status
+∞
36.0
34
*
GDG10
NOMESCO Finland
Bilateral transplantation of lung
+∞
34.9
33
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.7
33.6
167
667
R03BB04
ATC
tiotropium bromide; inhalant
5.3
31.9
73
163
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
7.4
31.0
48
73
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
+∞
30.6
29
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
9.4
29.8
37
43
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
8.3
27.7
38
50
R4110
NOMESCO Finland
Physiotherapy
3.2
26.8
170
768
WX721
NOMESCO Finland
Oxygen concentrator therapy
139.2
24.9
26
*
R03AK08
ATC
formoterol and beclometasone; inhalant
8.9
24.7
32
39
L04AD01
ATC
ciclosporin; systemic
+∞
24.2
23
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.9
23.3
180
893
A02BC02
ATC
pantoprazole; systemic
3.9
23.2
317
2153
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.5
23.0
101
361
L04AX01
ATC
azathioprine; systemic
89.1
23.0
25
*
XG466
NOMESCO Finland
Sleep oxymetry
7.4
22.5
34
50
R28
ICPC
Limited function/disability (R)
19.9
22.2
33
18
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
21.7
22.1
32
16
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
41.3
22.0
27
7
J45.9
ICD-10 Finland
Asthma, unspecified
3.7
22.0
82
263
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.5
21.6
91
316
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.2
20.4
61
167
R02
ICPC
Shortness of breath/dyspnoea
3.3
19.4
86
307
WX892
NOMESCO Finland
Monitored bed care
3.9
19.0
63
185
R05
ICPC
Cough
2.8
19.0
126
564
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
18.8
123
547
XX4BW, ,
NOMESCO Finland
199.5
18.7
19
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.5
17.7
211
1252
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
7.2
17.6
27
40
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
25.5
17.5
24
10
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
17.1
151
774
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.1
16.7
80
297
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
5.4
16.5
34
68
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.1
16.2
36
77
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.2
15.8
45
118
L04AD02
ATC
tacrolimus; systemic
+∞
15.7
15
*
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
24.6
15.3
21
9
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
5.0
15.3
34
73
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.7
14.7
24
38
R4190
NOMESCO Finland
Nutritional therapy
5.1
13.8
30
63
M05BA04
ATC
alendronic acid; oral
3.9
13.7
42
116
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
5.5
13.2
26
50
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
13.1
97
449
J01FA10
ATC
azithromycin; systemic
2.2
13.0
197
1243
J01AA02
ATC
doxycycline; systemic
2.7
13.0
312
2390
R03DC03
ATC
montelukast; oral
3.4
12.8
51
168
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.4
12.8
118
604
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.3
12.7
152
869
J45
ICD-10 Finland
Asthma
4.0
12.6
37
99
R03BA01
ATC
beclometasone; inhalant
3.2
12.4
52
177
N02AA05
ATC
oxycodone; systemic
2.4
12.3
110
555
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
4.1
12.2
35
92
J01MA14
ATC
moxifloxacin; systemic
3.4
12.0
46
148
A03FA01
ATC
metoclopramide; systemic, rectal
2.4
12.0
106
531
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
11.8
143
816
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
11.8
145
833
R03BA02
ATC
budesonide; inhalant
2.8
11.8
66
265
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.5
11.7
42
129
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
31.1
11.7
15
5
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.2
11.5
143
824
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.5
11.5
29
69
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.8
11.5
63
250
R03AK07
ATC
formoterol and budesonide; inhalant
2.7
11.4
73
313
J01CA04
ATC
amoxicillin; systemic
2.5
11.3
308
2403
G47.3
ICD-10 Finland
Sleep apnoea
2.2
11.2
121
658
H02AB07
ATC
prednisone; oral
3.7
11.0
36
104
XJC10
NOMESCO Finland
Oesophageal pH monitoring
44.7
11.0
13
*
D07AB02
ATC
hydrocortisone butyrate; topical
2.2
10.8
125
698
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.0
10.4
30
79
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
33.5
10.4
13
*
GX1K5
NOMESCO Finland
Diffusion capacity
24.1
10.3
14
6
R03AC03
ATC
terbutaline; inhalant
3.0
10.3
48
174
R06AE07
ATC
cetirizine; oral
2.1
10.1
145
874
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.4
10.0
37
116
J47
ICD-10 Finland
Bronchiectasis
9.9
9.9
19
20
ZX108
NOMESCO Finland
Inhalation
56.5
9.7
11
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
9.5
9.6
19
21
J01FA06
ATC
roxithromycin; oral
2.0
9.6
150
928
M05BA07
ATC
risedronic acid; oral
7.9
9.5
21
28
WW200
NOMESCO Finland
Immunization
8.4
9.5
20
25
GX1D5
NOMESCO Finland
Flow volume spirometry
30.9
9.5
12
*
R01AD08
ATC
fluticasone; nasal
2.2
9.4
101
542
GD1RA
NOMESCO Finland
Dynamic X-ray examination of respiratory organs with convetional X-ray picture
+∞
9.4
9
*
C03CA01
ATC
furosemide; systemic
2.0
8.9
150
948
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.8
8.9
46
176
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.5
8.7
61
272
H02AB04
ATC
methylprednisolone; systemic
3.0
8.6
40
144
R01AD58
ATC
fluticasone, combinations; nasal
2.3
8.5
76
378
N02AX02
ATC
tramadol; systemic, rectal
1.9
8.4
185
1270
XW5WT
NOMESCO Finland
Other blood specimen with radiologicl guidance
92.0
8.4
9
*
J45.1
ICD-10 Finland
Nonallergic asthma
3.6
8.4
28
82
A02BC05
ATC
esomeprazole; systemic
1.9
8.1
165
1101
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
17.6
8.1
12
7
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
6.3
8.0
20
33
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
11.1
7.9
14
13
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
7.7
176
1213
R5140
NOMESCO Finland
Monitoring the use of the aid
2.3
7.7
64
308
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
7.7
97
550
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.9
7.6
37
137
D07AC01
ATC
betamethasone; topical
1.9
7.5
144
940
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
81.6
7.4
8
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
13.7
7.4
12
9
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
7.4
105
619
A98
ICPC
Health maint/preventive medicine
4.5
7.4
370
3414
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
7.3
164
1120
5AB14, ,
NOMESCO Finland
+∞
7.3
7
*
WX727
NOMESCO Finland
Estimation of exercise oxygen therapy
+∞
7.3
7
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.5
7.3
46
195
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
30.6
7.2
9
*
R2110
NOMESCO Finland
Giving the first information
3.5
7.1
25
76
SPAT1325
SPAT
Vaccination
1.8
7.1
157
1066
I50.9
ICD-10 Finland
Heart failure, unspecified
2.1
7.1
73
383
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.9
7.1
34
125
ZXE00
NOMESCO Finland
One hour or less
1.8
7.0
151
1016
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.2
6.9
28
93
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.1
6.9
29
99
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
6.8
46
201
WPA11
NOMESCO Finland
Developing a plan for palliative care
17.1
6.8
10
6
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
6.7
158
1087
Z3226
NOMESCO Finland
Physiotherapist
2.0
6.7
80
442
WX726
NOMESCO Finland
High-flow oxygen therapy
23.0
6.7
9
*
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.8
6.7
199
1466
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
6.6
78
429
SPAT1262
SPAT
Handing over of treatment supplies
1.9
6.6
90
522
SPAT1058
SPAT
PEF monitoring instruction
2.6
6.5
40
167
J20
ICD-10 Finland
Acute bronchitis
2.5
6.4
41
175
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.0
6.4
28
98
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
18.4
6.3
9
5
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
7.2
6.3
14
20
2AX04, ,
NOMESCO Finland
+∞
6.3
6
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
2.8
6.3
31
116
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
5.5
6.2
17
32
E0000UV, ,
ATC
1.7
6.2
150
1035
C10AA01
ATC
simvastatin; oral
1.7
6.2
218
1669
R03BB01
ATC
ipratropium bromide; inhalant
4.2
6.1
16
39
GX2C5
NOMESCO Finland
Short-lasting oximetry
12.8
6.1
10
8
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.5
6.1
21
63
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
222
411
11.63
133.04
1.4
1.2
46.74
19.94
iu/ml
1.72
52
107
78
19
51.43
132.31
3.5
1.2
—
—
—
0
0
105
73
19.51
121.74
3.4
1.2
—
—
—
0
0
99
70
18.79
113.45
3.3
1.2
—
—
—
0
0
98
69
18.81
112.52
3.6
1.2
—
—
—
0
0
89
61
18.76
103.27
3.1
1.2
—
—
—
0
0
66
22
36.12
102.28
4.0
1.2
—
—
—
0
0
183
363
8.81
99.18
1.2
1.2
21.50
2.11
u/ml
1.21
33
115
155
277
8.78
91.50
2.4
1.4
—
—
—
0
0
69
36
23.21
90.63
3.5
1.3
—
—
—
0
0
54
16
39.19
86.22
1.0
1.1
—
—
—
0
0
61
27
26.73
85.46
3.2
1.2
—
—
—
0
0
111
144
10.49
85.07
4.4
2.5
—
—
—
0
0
90
89
12.95
83.63
3.2
1.3
—
—
—
0
0
201
522
7.07
81.24
11.5
8.2
1.51
0.79
mmol/l
2.29
179
434
201
527
6.99
80.27
11.7
8.3
5.04
5.06
kpa
0.11
196
511
190
481
6.92
78.44
3.5
1.7
—
—
—
0
0
360
1682
23.75
77.61
15.5
4.0
0.26
0.20
e9/l
6.80
332
1403
75
63
14.60
76.95
1.9
1.2
—
—
—
0
0
89
98
11.56
76.57
2.0
2.4
143.35
124.86
g/l
3.19
20
79
356
1658
19.90
76.39
14.6
4.0
2.00
1.99
e9/l
0.04
325
1407
179
458
6.51
72.16
3.7
1.7
—
—
—
0
0
76
74
12.60
70.89
1.4
1.3
9.93
5.63
iu/ml
0.40
13
19
65
51
15.18
69.17
2.0
1.2
—
—
—
0
0
57
36
18.46
68.05
1.5
1.2
174.69
168.65
au/ml
0.09
16
13
208
645
5.93
66.74
3.7
1.7
—
—
—
0
0
360
1847
19.93
65.18
17.4
7.6
4.71
4.18
e9/l
4.68
333
1560
362
1950
20.09
59.73
22.6
6.7
9.36
13.01
umol/l
12.56
362
1869
52
38
15.70
57.30
1.2
1.1
—
—
—
0
0
50
38
15.01
53.82
1.2
1.2
4.06
3.75
u/ml
0.06
33
16
52
44
13.54
52.54
1.2
1.0
174.29
—
titre
—
7
0
49
40
13.92
50.54
3.4
3.2
—
—
—
0
0
47
37
14.36
49.49
1.2
1.3
8.94
9.00
u/ml
0.00
17
14
50
51
11.14
44.59
1.2
1.2
1.70
4.31
u/ml
—
6
7
50
51
11.14
44.59
1.2
1.2
2.78
3.33
u/ml
—
5
7
64
100
7.50
40.61
3.7
1.9
203.11
207.66
%
0.13
64
95
40
35
12.66
39.33
1.1
1.1
424.03
265.67
u/ml
1.32
30
15
40
35
12.66
39.33
1.1
1.1
—
—
—
0
0
66
113
6.86
38.38
1.3
1.5
34.61
40.34
u/l
0.98
57
97
265
1368
4.12
36.83
4.3
3.0
1232.49
1347.24
ng/l
0.20
248
1193
68
135
5.92
33.92
1.2
1.1
165.25
182.65
u/ml
0.09
62
122
33
30
11.95
31.53
3.0
1.2
—
—
—
0
0
33
31
11.57
30.85
3.0
1.2
—
—
—
0
0
38
14
29.98
28.60
1.1
1.1
—
—
—
0
0
161
687
3.34
28.21
2.5
1.6
1.54
1.46
mg/l
0.06
135
543
288
1738
3.74
28.08
13.5
6.2
1.19
1.20
mmol/l
1.67
281
1583
105
344
3.84
27.74
4.9
2.9
135.25
200.48
ng/l
1.55
99
318
38
60
6.93
23.55
1.1
1.1
—
—
—
0
0
30
10
32.42
23.15
4.1
1.0
—
—
—
0
0
293
1919
3.32
22.24
13.7
6.7
1.20
1.20
mmol/l
0.45
270
1651
252
1525
2.95
21.95
21.1
10.6
0.00
0.00
e9/l
1.86
217
1222
26
8
34.75
20.46
4.3
1.6
24.04
52.84
ug/l
—
26
8
264
1695
2.84
19.52
7.6
4.9
33.97
34.95
g/l
2.27
251
1592
71
223
3.69
19.49
4.5
3.2
2.36
1.93
mmol/l
0.51
53
170
82
292
3.31
18.47
1.6
1.7
1.58
1.66
%
0.58
71
227
25
10
26.63
18.46
1.9
1.1
—
—
—
0
0
374
3223
13.16
18.30
36.5
16.0
23.90
28.90
mg/l
3.11
362
2642
76
260
3.41
18.24
1.8
1.6
—
—
—
0
0
24
9
28.34
18.04
1.9
1.0
—
—
—
0
0
151
774
2.58
17.14
5.1
3.9
643.53
409.47
ng/l
0.61
143
664
24
11
23.18
17.08
2.0
1.2
—
—
—
0
0
199
1175
2.46
16.48
5.4
2.1
133.51
263.90
u/l
1.27
192
1106
134
659
2.60
16.46
4.9
3.2
1.09
1.18
e6/l
0.07
73
348
226
1418
2.47
16.29
6.1
3.3
—
—
—
0
0
229
1446
2.47
16.26
3.1
2.1
—
—
—
0
0
190
1114
2.41
15.78
5.6
3.3
0.47
0.47
e6/l
0.00
148
814
24
15
16.99
15.45
1.9
1.0
—
—
—
0
0
137
701
2.49
15.29
4.5
3.1
0.70
0.96
e6/l
0.74
80
387
21
9
24.60
15.27
1.0
1.0
—
—
—
0
0
54
173
3.47
14.22
1.8
1.7
1.48
2.90
ug/l
0.56
48
155
204
1277
2.29
14.04
6.0
3.4
33.18
116.24
e6/l
0.92
164
973
128
664
2.40
13.60
3.0
1.8
29.36
29.92
s
0.52
128
651
301
2260
2.61
13.16
13.4
5.3
6.95
6.85
mmol/l
0.44
291
2162
156
892
2.27
13.13
9.2
2.5
346.44
365.99
umol/l
1.72
140
739
20
12
17.51
13.12
2.7
1.3
—
—
—
0
0
24
23
11.06
12.94
2.5
1.3
—
—
—
0
0
25
51
5.18
11.85
1.7
1.2
—
—
—
0
0
25
51
5.18
11.85
1.7
1.2
—
—
—
0
0
15
5
31.13
11.73
1.1
1.0
—
—
—
0
0
268
1968
2.24
11.40
19.6
17.4
1.32
1.33
inr
0.11
227
1636
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
44
144
3.33
11.15
3.5
2.4
0.31
0.38
iu/ml
0.62
21
71
196
1291
2.07
10.93
6.2
3.5
2.34
2.35
mmol/l
0.23
187
1153
32
87
3.93
10.65
2.9
1.5
—
—
—
0
0
16
11
15.12
10.08
1.0
1.1
—
—
—
0
0
44
158
3.02
9.55
5.1
2.2
520.60
811.47
ug/l
0.38
44
152
82
403
2.32
9.49
2.7
2.6
11.26
10.49
umol/l
0.08
72
365
50
195
2.80
9.35
1.5
1.4
—
—
—
0
0
60
258
2.57
9.27
1.8
1.5
—
—
—
0
0
19
24
8.27
8.96
1.1
1.1
—
—
—
0
0
19
39
5.08
8.93
2.5
1.5
87.67
89.18
%
0.39
19
39
15
14
11.10
8.36
5.9
2.8
—
—
—
0
0
141
889
1.93
8.32
4.3
2.5
2.46
3.95
e6/l
3.31
132
796
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
13
9
14.90
8.26
1.5
1.1
217.85
202.44
%
—
13
9
19
29
6.84
7.99
1.3
1.2
—
—
—
0
0
19
29
6.84
7.99
1.3
1.2
—
—
—
0
0
19
29
6.84
7.99
1.3
1.2
—
—
—
0
0
236
1784
1.86
7.65
5.3
3.7
0.00
0.00
estimate
-0.00
53
384
17
24
7.36
7.56
1.0
1.1
—
—
—
0
0
19
45
4.39
7.56
1.3
1.3
325.51
0.30
iu/ml
—
11
8
15
19
8.17
7.17
1.0
1.2
—
—
—
0
0
15
19
8.17
7.17
1.0
1.2
—
—
—
0
0
15
19
8.17
7.17
1.0
1.2
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
12
10
12.34
7.12
1.0
1.4
109.33
86.30
%
—
12
10
238
1828
1.81
7.06
5.5
3.8
0.00
0.87
estimate
0.51
51
351
15
20
7.76
6.96
1.0
1.2
—
—
—
0
0
236
1820
1.79
6.78
5.4
3.8
22.21
0.01
estimate
0.49
53
390
17
41
4.29
6.62
1.0
1.0
—
—
u/ml
—
0
0
195
1437
1.74
6.45
3.3
2.2
69.77
78.03
nmol/l
5.03
180
1229
91
538
1.91
6.28
9.2
4.6
1.05
1.02
mmol/l
0.33
86
500
75
418
1.99
6.13
2.8
3.4
2.42
1.72
mmol/l
0.72
64
345
10
9
11.37
5.82
1.0
1.8
17.50
16.89
%
—
10
9
28
106
2.77
5.54
3.9
2.6
4.87
1.50
index
1.11
15
60
18
52
3.58
5.52
2.6
2.4
11.28
11.27
mmol/l
0.00
18
52
8
6
13.58
5.10
1.5
3.3
15.51
13.43
ml/dl
—
8
6
18
57
3.27
4.83
1.3
1.1
—
2.73
—
0
6
94
612
1.71
4.60
1.9
2.6
2.33
2.20
g/l
1.68
89
561
9
11
8.35
4.58
1.1
2.1
—
—
—
0
0
192
1524
1.53
3.99
5.0
4.1
43.67
45.52
ng/l
0.06
164
1237
6
5
12.16
3.77
1.0
1.2
—
—
—
0
0
17
61
2.87
3.74
1.9
1.3
—
—
—
0
0
9
16
5.73
3.68
1.0
1.1
—
—
—
0
0
49
284
1.83
3.53
3.3
3.0
53.05
60.06
ml/min/173m2
0.67
22
118
20
81
2.55
3.52
1.8
1.5
—
—
—
0
0
6
7
8.68
3.27
2.0
1.1
249.33
207.00
%
—
6
7
6
8
7.60
3.06
1.2
1.0
—
—
—
0
0
6
8
7.60
3.06
1.2
1.0
—
—
—
0
0
20
87
2.37
3.06
1.2
1.1
—
—
—
0
0
20
87
2.37
3.06
1.2
1.1
—
—
—
0
0
109
806
1.49
3.01
5.4
4.1
1.02
1.02
kg/l
0.16
74
549
148
1163
1.45
2.99
3.2
2.6
61.56
66.35
u/l
0.36
140
1069
6
9
6.75
2.87
1.2
1.0
—
—
—
0
0
137
1068
1.44
2.87
4.9
3.8
0.00
0.01
estimate
0.50
49
341
6
10
6.08
2.70
1.2
1.0
—
—
—
0
0
6
10
6.08
2.70
1.2
1.0
—
—
—
0
0
6
10
6.08
2.70
1.2
1.0
—
—
—
0
0
6
10
6.08
2.70
1.2
1.0
—
—
—
0
0
234
2020
1.41
2.70
7.9
3.2
55.17
63.64
u/l
0.96
224
1850
28
148
1.96
2.69
2.4
1.9
36.75
49.55
mg/l
0.42
23
133
22
106
2.14
2.68
1.3
1.3
—
—
—
0
0
166
1352
1.41
2.68
5.0
3.8
0.00
0.00
estimate
0.50
46
314
28
149
1.95
2.64
2.4
1.9
70.14
84.08
mg/l
0.14
23
134
23
116
2.05
2.51
1.4
1.2
—
—
—
0
0
344
3222
1.73
2.51
32.7
17.5
72.81
74.38
ml/min/173m2
0.87
321
3007
5
8
6.31
2.38
1.0
1.0
—
—
—
0
0
10
33
3.08
2.37
1.4
1.5
—
—
—
0
0
326
3038
1.52
2.14
5.0
5.0
2.14
2.06
mu/l
0.54
300
2706
7
20
3.55
2.06
1.1
1.2
111.43
89.10
pmol/l
—
7
20
115
924
1.35
1.90
2.7
2.4
—
—
—
0
0
22
122
1.85
1.88
2.3
1.5
—
—
—
0
0
5
12
4.21
1.83
1.0
1.2
679.00
647.42
u/ml
—
5
12
22
124
1.82
1.80
1.0
1.0
—
—
—
0
0
350
3338
1.63
1.78
6.8
6.9
2.42
2.50
mmol/l
1.11
327
3038
177
1526
1.30
1.76
4.5
4.1
6.48
8.49
mg/mmol
0.45
121
963
23
134
1.76
1.70
2.6
1.9
3.62
2.04
ratio
0.47
11
69
40
270
1.54
1.70
2.3
3.7
72.46
101.56
ng/l
1.81
35
234
174
1504
1.29
1.67
3.7
3.4
7.59
7.85
mmol/l
0.41
151
1242
102
821
1.33
1.65
2.0
1.8
94318604.45
14652986.30
pmol/l
0.39
88
662
17
91
1.91
1.63
1.3
1.2
—
—
—
0
0
194
1709
1.28
1.58
3.9
2.8
—
—
estimate
—
0
0
22
130
1.73
1.56
2.6
1.5
—
—
—
0
0
19
108
1.80
1.53
1.7
1.7
—
—
—
0
0
167
1449
1.27
1.52
2.6
2.9
183.01
164.32
ug/l
0.39
158
1317
343
3275
1.50
1.51
6.3
6.0
6.23
6.16
mmol/l
0.55
319
2945
267
2456
1.29
1.50
3.7
3.9
14.24
15.01
pmol/l
5.96
244
2157
35
237
1.53
1.48
3.4
3.8
52.95
48.39
%
0.43
35
230
5
16
3.15
1.44
7.0
5.8
1.00
0.94
%
—
5
16
100
819
1.30
1.42
2.2
3.3
2.47
2.45
mmol/l
1.15
93
737
338
3229
1.43
1.37
8.1
7.8
41.34
40.34
mmol/mol
1.48
319
2973
41
294
1.44
1.33
1.3
1.3
—
—
—
0
0
328
3123
1.37
1.31
5.1
4.8
1.36
1.26
mmol/l
2.29
295
2813
8
36
2.25
1.25
1.0
1.3
—
—
—
0
0
8
37
2.19
1.22
1.0
1.3
—
—
—
0
0
8
37
2.19
1.22
1.0
1.3
—
—
—
0
0
8
38
2.13
1.19
1.0
1.3
—
—
—
0
0
8
38
2.13
1.19
1.0
1.3
—
—
—
0
0
8
38
2.13
1.19
1.0
1.3
—
—
—
0
0
54
417
1.34
1.16
4.6
3.3
—
—
—
0
0
5
21
2.40
1.09
1.4
1.1
—
—
—
0
0
5
21
2.40
1.09
1.4
1.1
—
—
—
0
0
116
997
1.24
1.09
2.3
2.2
2.86
2.86
mg/l
0.01
104
843
338
3257
1.35
1.02
5.9
5.7
1.35
1.40
mmol/l
1.64
311
2949
9
48
1.90
1.01
1.2
1.4
—
—
—
0
0
17
111
1.56
0.89
3.5
2.7
29.88
36.76
umol/l
1.14
17
99
10
56
1.81
0.88
1.1
1.1
—
—
—
0
0
338
3271
1.31
0.86
6.0
5.9
4.25
4.34
mmol/l
0.91
313
2996
84
716
1.22
0.85
1.7
1.8
1079.37
1222.63
nmol/l
0.94
67
544
6
31
1.95
0.84
1.0
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
106
933
1.19
0.77
5.0
3.3
0.00
0.09
estimate
0.50
40
287
8
132
0.60
0.75
1.0
1.2
—
97.07
—
0
47
6
108
0.55
0.73
1.7
1.9
51.50
47.41
nmol/l
—
6
98
5
25
2.01
0.73
1.0
1.0
—
—
—
0
0
5
29
1.73
0.64
1.2
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
10
64
1.58
0.59
1.3
1.6
—
—
—
0
0
6
38
1.59
0.54
2.5
2.5
—
—
—
0
0
13
91
1.44
0.53
2.7
1.5
67.89
4.81
mg/l
2.55
13
74
116
1261
0.88
0.49
3.1
3.6
0.68
0.76
ug/l
0.30
94
907
27
217
1.26
0.49
1.6
1.7
1.27
1.59
g/l
1.31
22
186
10
68
1.48
0.47
1.0
1.1
—
—
—
0
0
42
489
0.84
0.45
5.2
5.5
31.31
32.05
%
0.23
32
297
16
121
1.34
0.45
2.2
1.7
0.00
0.00
g/l
-0.00
16
116
189
1792
1.11
0.44
1.9
2.2
85.36
94.86
pmol/l
1.95
99
921
0
17
0.00
0.40
0.0
1.4
—
39.76
—
0
17
5
35
1.43
0.39
2.6
2.8
639.20
1149.14
mg
—
5
35
0
19
0.00
0.39
0.0
1.9
—
89.24
—
0
19
164
1729
0.91
0.39
4.2
5.2
23.37
21.73
%
0.47
62
940
72
654
1.12
0.36
1.3
1.2
1.35
1.44
u/ml
0.04
17
167
41
466
0.87
0.35
10.0
8.3
—
—
—
0
0
13
100
1.31
0.34
1.2
1.6
—
—
—
0
0
141
1488
0.92
0.33
2.1
2.0
1.51
1.26
mmol/l
3.01
123
1191
16
128
1.26
0.32
2.2
2.4
155.50
100.81
ug/min
—
10
74
25
213
1.19
0.30
1.5
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
17
198
0.85
0.21
3.4
3.9
338.36
2273.06
u/ml
1.31
11
177
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
1.22
—
0
9
129
1239
1.06
0.20
1.7
1.7
18.52
20.14
nmol/l
0.77
119
1009
6
50
1.20
0.20
1.8
2.9
1.23
1.19
mmol/l
—
6
50
6
51
1.18
0.19
1.8
2.8
105.33
105.63
mmol/l
—
6
51
7
58
1.21
0.18
3.1
2.7
9.90
11.52
pmol/l
—
7
58
7
90
0.77
0.14
1.0
1.3
—
—
—
0
0
13
149
0.87
0.14
1.4
2.9
4.17
4.29
pmol/l
—
7
128
14
125
1.12
0.10
1.2
1.6
0.27
0.32
mg/l
—
8
64
5
45
1.11
0.10
1.0
1.2
—
109.83
—
0
6
11
118
0.93
0.03
2.4
3.1
1.59
1.67
mmol/l
0.16
11
113
214
2128
1.01
0.02
4.8
6.4
1.80
3.01
ug/l
1.76
194
1892
17
173
0.98
0.00
1.1
1.3
—
61.05
—
0
17
8
84
0.95
0.00
1.0
1.4
—
—
—
0
0
7
73
0.96
-0.00
1.1
1.2
1.04
0.77
nmol/l
—
7
60
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
40.17
—
0
6
7
73
0.96
-0.00
1.6
1.2
—
—
—
0
0
6
61
0.98
-0.00
1.3
1.2
3.48
3.94
mmol/l
—
6
61
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.2
—
104.24
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1.15
—
0
6
0
9
0.00
-0.00
0.0
3.8
—
13.51
—
0
9
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
17.4
—
6.02
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
91
0.99
-0.00
1.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: ILD_PIRFENIDONE – ILD medications: pirfenidone
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).