No definition available.
Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist
EFO MESH Endpoint Browser PheWeb
M13_CHRONSYNOVITISHANDWRIST
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
604 |
4. Check minimum number of eventsNone |
604 |
5. Include endpointsNone |
604 |
6. Filter based on genotype QC (FinnGen only) |
542 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist
based on the number of shared cases.
Similar with more cases:
- Soft tissue disorders related to use, overuse and pressure
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3653 | 2118 | 1522 |
| Only index persons | 3478 | 2036 | 1442 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.04 |
| Only index persons | 0.07 | 0.07 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 51.39 | 52.07 | 50.41 |
| Only index persons | 50.83 | 51.70 | 49.59 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 542 | 357 | 185 |
| Unadjusted period prevalence (%) | 0.11 | 0.13 | 0.08 |
| Median age at first event (years) | 52.51 | 52.03 | 53.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 563
- Matched controls
- 5630
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M70.0
ICD-10 Finland
Chronic crepitant synovitis of hand and wrist
3173.8
307.7
356
*
M70.1
ICD-10 Finland
Bursitis of hand
479.9
120.5
116
*
M77.2
ICD-10 Finland
Periarthritis of wrist
+∞
91.2
85
*
M79.0
ICD-10 Finland
Rheumatism, unspecified
53.6
85.1
49
10
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
26.3
80.7
57
24
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
19.7
71.5
57
32
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
189.7
65.6
67
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
5.4
60.7
146
344
M75.1
ICD-10 Finland
Rotator cuff syndrome
4.6
59.5
186
542
M65.3
ICD-10 Finland
Trigger finger
12.3
56.2
58
52
M79.6
ICD-10 Finland
Pain in limb
3.8
52.8
304
1341
M25.5
ICD-10 Finland
Pain in joint
3.5
47.0
262
1113
N03AX16
ATC
[U] pregabalin
3.8
44.9
184
638
M67.4
ICD-10 Finland
Ganglion
8.3
44.6
62
83
N02AX02
ATC
tramadol; systemic, rectal
3.3
43.3
301
1446
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
16.7
42.1
36
23
M19.0
ICD-10 Finland
Primary arthrosis of other joints
5.2
40.6
93
206
M70.6
ICD-10 Finland
Trochanteric bursitis
4.3
37.1
112
309
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
7.9
36.2
52
72
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
8.0
35.3
50
68
M65.4
ICD-10 Finland
Radial styloid tenosynovitis [de Quervain]
9.9
33.0
39
42
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
8.6
31.1
41
51
N06AX21
ATC
duloxetine; oral
4.0
30.7
99
285
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.7
30.4
287
1547
N03AX12
ATC
[U] gabapentin; oral
3.5
28.5
116
390
M77.1
ICD-10 Finland
Lateral epicondylitis
4.8
28.2
68
156
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.3
28.2
80
209
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
5.0
28.1
64
140
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.1
28.0
87
243
NDL52
NOMESCO Finland
Tenosynovectomy of hand
79.2
27.0
30
*
M54.5
ICD-10 Finland
Low back pain
2.6
26.8
241
1248
M01AC06
ATC
meloxicam; systemic, rectal
2.6
26.8
247
1295
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.6
26.7
99
312
M54.4
ICD-10 Finland
Lumbago with sciatica
3.2
26.7
131
492
M70.2
ICD-10 Finland
Olecranon bursitis
8.4
25.4
34
43
Z01.8
ICD-10 Finland
Other specified special examinations
2.8
25.1
168
747
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
73.4
25.0
28
*
M13.9
ICD-10 Finland
Arthritis, unspecified
4.5
24.8
64
155
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
24.7
235
1240
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.3
24.0
106
372
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
23.5
268
1527
M01AH05
ATC
etoricoxib; oral
2.5
22.8
389
2642
J01AA02
ATC
doxycycline; systemic
3.2
22.3
482
3657
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.4
22.2
89
294
ZXA00
NOMESCO Finland
Right side
2.6
22.0
174
833
M48.0
ICD-10 Finland
Spinal stenosis
3.4
21.8
86
281
M01AE03
ATC
ketoprofen; systemic, rectal
2.4
21.8
236
1305
M01AX17
ATC
nimesulide; oral
2.6
21.7
160
740
P01BA02
ATC
hydroxychloroquine; oral
3.8
21.5
70
201
M01AE02
ATC
naproxen; oral, rectal
2.4
21.4
355
2350
M79.7
ICD-10 Finland
Fibromyalgia
17.4
21.2
33
20
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.4
21.1
56
138
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.5
21.1
191
972
G44.2
ICD-10 Finland
Tension-type headache
3.1
20.6
99
364
ZXA05
NOMESCO Finland
Left side
2.6
20.1
155
730
ACC51
NOMESCO Finland
Release of median nerve
4.0
19.6
59
160
N06AA09
ATC
amitriptyline; systemic
3.5
19.4
73
231
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.6
19.3
70
216
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
57.1
19.1
22
*
NF1AA
NOMESCO Finland
Hip X-ray examination
3.6
19.0
68
208
M01AB05
ATC
diclofenac; systemic, rectal
2.4
18.9
401
2878
A02BC02
ATC
pantoprazole; systemic
2.4
18.9
414
3013
A01
ICPC
Pain general/multiple sites
3.4
18.8
73
235
M77.9
ICD-10 Finland
Enthesopathy, unspecified
7.3
18.8
28
40
L04AX03
ATC
methotrexate; systemic
3.3
18.8
78
262
J01DB01
ATC
cefalexin; oral
3.0
18.6
488
3849
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.9
18.6
59
166
J01FF01
ATC
clindamycin; systemic
2.4
18.6
181
943
H02AB06
ATC
prednisolone; systemic
2.2
18.5
291
1844
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.4
18.3
47
113
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.4
18.2
70
224
L08
ICPC
Shoulder symptom/complaint
2.5
18.1
141
663
R51.80
ICD-10 Finland
Headache
2.7
17.8
108
449
M01AH01
ATC
celecoxib; oral
2.6
17.6
121
535
N02BF02
ATC
pregabalin; oral
4.0
17.3
51
136
M02AA07
ATC
piroxicam; topical
2.2
17.1
215
1237
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.4
17.0
146
716
M02AA10
ATC
ketoprofen; topical
2.6
16.7
111
483
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.4
16.6
140
680
A02BC05
ATC
esomeprazole; systemic
2.1
16.5
246
1509
A06AC01
ATC
ispaghula (psylla seeds); oral
2.2
16.1
176
953
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.9
16.0
83
317
L86
ICPC
Back syndrome with radiating pain
3.9
15.9
48
130
J01DA01
ATC
[U] cefalexin
2.1
15.9
362
2585
X59
ICD-10 Finland
Exposure to unspecified factor
2.5
15.9
116
527
S18
ICPC
Laceration/cut
2.1
15.7
285
1871
R03AC02
ATC
salbutamol; inhalant
2.1
15.6
331
2298
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.7
15.4
50
143
A07EC01
ATC
sulfasalazine; oral, rectal
3.4
15.3
59
189
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
5.8
15.2
28
50
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
46.4
15.1
18
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
15.1
311
2124
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
15.1
170
929
A02BC03
ATC
lansoprazole; oral
2.2
14.9
177
986
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.4
14.9
56
176
M54.3
ICD-10 Finland
Sciatica
3.8
14.8
47
132
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
19.0
14.8
22
12
M01AX05
ATC
glucosamine; oral
2.4
14.7
125
607
SPAT1202
SPAT
Intra-articular injection
5.6
14.6
28
52
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
6.8
14.6
23
35
M03BX02
ATC
tizanidine; oral
2.1
14.6
370
2711
M79.1
ICD-10 Finland
Myalgia
2.7
14.3
86
354
M70.7
ICD-10 Finland
Other bursitis of hip
5.9
14.3
26
46
M01AH02
ATC
rofecoxib; oral
2.7
14.3
83
336
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
14.1
156
843
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.4
14.1
52
162
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.8
14.0
74
285
N02BE01
ATC
paracetamol; systemic, rectal
3.2
13.7
517
4393
C03CA01
ATC
furosemide; systemic
2.1
13.7
169
952
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.4
13.7
52
165
M01AX01
ATC
nabumetone; oral
4.5
13.6
34
80
A02BC01
ATC
omeprazole; systemic
2.1
13.5
162
902
K30
ICD-10 Finland
Functional dyspepsia
2.7
13.5
80
327
S80.0
ICD-10 Finland
Contusion of knee
3.1
13.4
58
199
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
5.5
13.4
26
49
Z3226
NOMESCO Finland
Physiotherapist
2.4
13.3
110
525
R42
ICD-10 Finland
Dizziness and giddiness
2.2
13.3
144
770
J01DA09
ATC
[U] cefadroxil
2.1
13.1
164
926
L11
ICPC
Wrist symptom/complaint
2.9
13.1
64
236
R60.0
ICD-10 Finland
Localized oedema
2.6
12.9
82
346
N06AX16
ATC
venlafaxine; oral
2.4
12.9
96
437
R4120
NOMESCO Finland
Occupational therapy
3.4
12.8
47
146
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
6.1
12.7
22
37
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
17.8
12.6
19
11
M43.1
ICD-10 Finland
Spondylolisthesis
4.2
12.6
34
85
L03
ICPC
Low back symptom/complaint
2.0
12.4
168
974
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
12.4
64
243
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
3.2
12.4
51
170
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.9
12.4
268
1822
X58
ICD-10 Finland
Exposure to other specified factors
2.4
12.4
91
412
J01FA06
ATC
roxithromycin; oral
1.9
12.2
231
1500
M09AX01
ATC
hyaluronic acid; parenteral
3.9
12.2
36
96
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
12.2
269
1837
UJF32
NOMESCO Finland
Coloscopy
2.1
12.1
154
872
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.9
12.0
36
97
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.6
12.0
78
333
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.9
11.9
60
225
M03BC01
ATC
orphenadrine (citrate); systemic
2.1
11.8
134
726
L12
ICPC
Hand/finger symptom/complaint
2.3
11.8
104
509
WX204
NOMESCO Finland
Axillary plexus blockaced
4.6
11.8
28
63
H02AB04
ATC
methylprednisolone; systemic
2.4
11.7
89
408
SPAT1153
SPAT
Removal of sutures
2.0
11.7
181
1096
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
11.7
157
905
R96
ICPC
Asthma
2.7
11.6
68
275
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
11.4
11.6
21
19
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.9
11.6
35
95
A02BA04
ATC
nizatidine; systemic
3.0
11.5
52
183
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
5.5
11.4
22
41
H02AB07
ATC
prednisone; oral
2.4
11.4
83
373
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.5
11.3
76
329
J01MA02
ATC
ciprofloxacin; systemic
1.9
11.3
218
1416
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.8
11.3
316
2307
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.3
11.2
29
70
M01AB55
ATC
diclofenac, combinations; oral
3.2
11.2
46
153
M77.4
ICD-10 Finland
Metatarsalgia
3.6
11.0
37
108
N06AX11
ATC
mirtazapine; oral
1.9
11.0
201
1282
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.7
10.9
64
259
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
10.9
112
583
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
10.9
10.8
20
19
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
5.1
10.8
23
47
M77.0
ICD-10 Finland
Medial epicondylitis
5.7
10.8
20
36
A07AA02
ATC
nystatin; oral
3.4
10.7
39
120
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
10.7
114
601
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
10.6
170
1037
N02BF01
ATC
gabapentin; oral
2.7
10.6
58
227
G56.2
ICD-10 Finland
Lesion of ulnar nerve
5.0
10.6
23
48
L13
ICPC
Hip symptom/complaint
2.1
10.6
114
604
L28
ICPC
Limited function/disability (L)
2.2
10.6
106
546
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.0
10.5
130
725
M19.9
ICD-10 Finland
Arthrosis, unspecified
3.9
10.4
31
83
9502
FHL
Tendon splitting (De Quervain, click finger)
+∞
10.4
10
*
7264A
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of wrist and carpus
+∞
10.4
10
*
M01AH03
ATC
valdecoxib; oral
3.2
10.4
41
133
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.2
10.3
43
144
R53
ICD-10 Finland
Malaise and fatigue
2.0
10.3
146
852
M47.9
ICD-10 Finland
Spondylosis, unspecified
4.7
10.3
24
53
R52.2
ICD-10 Finland
Other chronic pain
4.0
10.2
29
75
L17
ICPC
Foot/toe symptom/complaint
1.9
10.2
168
1033
L15
ICPC
Knee symptom/complaint
1.9
10.1
151
897
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
10.1
107
562
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
9.4
10.1
20
22
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.8
10.1
52
197
K59.09
ICD-10 Finland
Constipation, unspecified
3.0
9.9
44
153
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.9
9.9
29
77
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
9.9
112
604
NDA30
NOMESCO Finland
Exploration of joint of wrist or hand, arthroscopic
26.5
9.8
13
5
M54.2
ICD-10 Finland
Cervicalgia
2.8
9.8
49
183
M71.1
ICD-10 Finland
Other infective bursitis
56.0
9.7
11
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
9.6
105
557
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
5.1
9.6
20
40
AA1AD
NOMESCO Finland
CT of head and brain
1.9
9.6
160
983
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
9.6
207
1377
A10AB01
ATC
insulin (human); parenteral
4.1
9.6
26
65
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
3.5
9.6
33
98
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
9.5
171
1076
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.3
9.5
79
376
H02BX01
ATC
methylprednisolone, combinations; systemic
3.6
9.5
31
89
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.8
9.5
50
192
A10AA01, ,
ATC
4.5
9.4
23
53
M70.4
ICD-10 Finland
Prepatellar bursitis
8.9
9.4
19
22
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.2
9.2
80
388
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.3
9.2
34
106
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
9.2
230
1595
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
3.1
9.1
39
133
R02
ICPC
Shortness of breath/dyspnoea
2.2
9.1
79
383
P03
ICPC
Feeling depressed
2.5
9.1
61
264
ND2AA, ,
SPAT
3.1
9.1
38
128
M71.0
ICD-10 Finland
Abscess of bursa
37.3
9.0
11
*
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.3
9.0
70
323
M03BC51
ATC
orphenadrine, combinations; systemic
1.9
9.0
152
935
M20.2
ICD-10 Finland
Hallux rigidus
3.8
9.0
27
73
B01AB05
ATC
enoxaparin; parenteral
1.8
9.0
175
1126
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
4.0
9.0
25
64
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
4.0
9.0
25
64
TQW40
NOMESCO Finland
Remowal of suture of skin
2.8
8.9
46
174
H04AA01
ATC
glucagon; nasal, parenteral
8.2
8.9
19
24
M18.0
ICD-10 Finland
Primary arthrosis of first carpometacarpal joints, bilateral
8.8
8.9
18
21
R01BA52
ATC
pseudoephedrine, combinations; oral
1.8
8.8
179
1164
WX120
NOMESCO Finland
Intravenous local anesthesy of arm
10.9
8.8
16
15
Z50.1
ICD-10 Finland
Other physical therapy
3.2
8.8
35
114
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.1
8.8
37
125
A01AB09
ATC
miconazole; local oral
2.6
8.8
54
224
N02AA05
ATC
oxycodone; systemic
2.1
8.8
98
524
M01AE01
ATC
ibuprofen; systemic, rectal
2.4
8.7
510
4508
N05CF01
ATC
zopiclone; oral
1.8
8.7
178
1160
C09CA01
ATC
losartan; oral
1.8
8.7
154
961
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.0
8.6
38
132
R01AD09
ATC
mometasone; nasal
1.7
8.6
255
1843
C10AA01
ATC
simvastatin; oral
1.7
8.6
217
1501
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.1
8.5
86
442
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.3
8.5
67
311
SPAT1263
SPAT
Sampling
1.7
8.5
222
1548
NDL54
NOMESCO Finland
Tenolysis of hand
28.0
8.5
11
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
8.5
39
139
NCM20
NOMESCO Finland
Excision of synovial ganglion of elbow or forearm
91.4
8.4
9
*
SPAT1255
SPAT
Intravenous administration of medicine
2.9
8.4
40
145
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
4.1
8.4
23
58
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
13.0
8.4
14
11
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
8.4
395
3223
M54.6
ICD-10 Finland
Pain in thoracic spine
2.7
8.4
47
186
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
8.4
395
3224
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
8.4
96
518
NCL22
NOMESCO Finland
Myotomy or tenotomy of elbow or forearm
+∞
8.4
8
*
NFM20
NOMESCO Finland
Excision of bursa of hip or thigh
+∞
8.4
8
*
WZC30
NOMESCO Finland
Teaching
2.0
8.3
98
533
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
8.3
86
446
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.9
8.3
24
63
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.6
8.2
50
206
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.6
8.2
48
194
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
8.2
339
2662
J01FA09
ATC
clarithromycin; systemic
1.8
8.2
174
1144
J01CA04
ATC
amoxicillin; systemic
1.9
8.2
451
3839
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.6
8.2
50
207
N02AC04
ATC
dextropropoxyphene; oral
3.9
8.1
24
64
M01AC01
ATC
piroxicam; systemic, rectal
2.2
8.1
74
365
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.0
8.1
37
131
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.4
8.1
55
239
A02BA02
ATC
ranitidine; systemic
2.0
8.1
104
584
M19.8
ICD-10 Finland
Other specified arthrosis
3.4
8.0
29
89
P01AB01
ATC
metronidazole; oral, rectal
1.7
8.0
227
1612
WX320
NOMESCO Finland
Spinalanesthesy
1.8
8.0
134
820
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
8.0
206
1428
S62.6
ICD-10 Finland
Fracture of other finger
3.2
7.9
31
100
SGA01
NOMESCO Finland
Emergency treatment
2.0
7.9
94
513
SPAT1229
SPAT
Assessment of need for aid
2.7
7.9
42
162
A10AC01
ATC
insulin (human); parenteral
2.6
7.9
47
192
SPAT1216
SPAT
Assessment of functional ability
2.1
7.9
80
412
J02AC01
ATC
fluconazole; systemic
1.7
7.8
225
1601
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
7.8
100
561
WZC00, ,
SPAT
2.0
7.8
87
465
D06
ICPC
Abdominal pain localized other
2.4
7.7
52
225
J01FA10
ATC
azithromycin; systemic
1.6
7.7
308
2381
ZXD20
NOMESCO Finland
Day surgery
2.2
7.7
69
338
R05
ICPC
Cough
1.8
7.7
143
901
A10AB04
ATC
insulin lispro; parenteral
3.8
7.7
23
62
C08CA01
ATC
amlodipine; oral
1.7
7.7
213
1500
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
7.7
48
201
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.7
7.7
24
67
C07AB02
ATC
metoprolol; systemic
1.9
7.6
105
602
M47.82
ICD-10 Finland
Other spondylosis, cervical region
3.6
7.6
25
72
S01
ICPC
Pain/tenderness of skin
3.3
7.6
28
87
R05
ICD-10 Finland
Cough
1.8
7.6
122
736
M24.2
ICD-10 Finland
Disorder of ligament
9.0
7.6
15
17
R52.9
ICD-10 Finland
Pain, unspecified
2.3
7.5
57
260
R4110
NOMESCO Finland
Physiotherapy
1.7
7.5
153
990
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.0
7.5
34
120
R03DC03
ATC
montelukast; oral
2.0
7.5
93
515
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
4.5
7.5
18
41
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.5
7.5
18
41
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
2.5
7.5
46
191
N01
ICPC
Headache
2.3
7.5
61
288
NBG10
NOMESCO Finland
Acromioplastia
13.6
7.4
12
9
L10
ICPC
Elbow symptom/complaint
2.9
7.4
34
121
WX704
NOMESCO Finland
Intubation
2.4
7.4
50
217
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
7.4
72
365
J45.1
ICD-10 Finland
Nonallergic asthma
2.6
7.4
43
174
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
11.1
7.3
13
12
M62.6
ICD-10 Finland
Muscle strain
4.2
7.3
19
46
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.2
7.3
19
46
NCL50
NOMESCO Finland
Tenolysis or tenosynovectomy of elbow or forearm
+∞
7.3
7
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
7.3
72
367
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.6
7.3
41
163
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.1
7.2
71
361
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
4.0
7.2
20
51
A10AA02, ,
ATC
3.6
7.2
23
65
A10AE06
ATC
insulin degludec; parenteral
3.3
7.2
27
85
NC1BG
NOMESCO Finland
Elbow MRI examination with high intensity magnet
30.4
7.2
9
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
7.2
121
740
F51.0
ICD-10 Finland
Nonorganic insomnia
1.9
7.2
100
576
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
6.7
7.2
17
26
SFA10
NOMESCO Finland
One-surface restoration
1.6
7.2
298
2312
H3603, E103,
ICD-10 Finland
20.3
7.2
10
5
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
4.1
7.1
19
47
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
4.1
7.1
19
47
M76.0
ICD-10 Finland
Gluteal tendinitis
5.7
7.1
19
34
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
2.1
7.1
67
335
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
7.1
262
1973
C07AB07
ATC
bisoprolol; oral
1.6
7.1
257
1927
M75.8
ICD-10 Finland
Other shoulder lesions
3.6
7.1
23
66
G43.9
ICD-10 Finland
Migraine, unspecified
2.7
7.0
37
142
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
2.6
7.0
42
172
R06.0
ICD-10 Finland
Dyspnoea
1.7
7.0
140
899
K02.1
ICD-10 Finland
Caries of dentine
1.6
7.0
316
2495
C10AA05
ATC
atorvastatin; oral
1.6
7.0
231
1692
A10AE04
ATC
insulin glargine; parenteral
2.2
7.0
57
269
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
7.0
62
303
L16
ICPC
Ankle symptom/complaint
2.1
6.9
65
325
T78.4
ICD-10 Finland
Allergy, unspecified
3.1
6.9
28
93
M70.5
ICD-10 Finland
Other bursitis of knee
11.1
6.8
12
11
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
9.5
6.8
13
14
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
6.8
92
524
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.4
6.8
17
40
K04.1
ICD-10 Finland
Necrosis of pulp
2.1
6.7
67
342
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.9
6.7
31
111
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.8
6.7
101
596
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
4.1
6.7
18
45
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
4.1
6.7
18
45
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
6.0
6.7
17
29
310
Kela drug reimbursment
Orlistat, sibutramine and other major and expensive medicines used to treat obesity
7.9
6.6
14
18
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
6.6
104
621
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
12.4
6.6
11
9
L02
ICPC
Back symptom/complaint
2.1
6.6
60
296
M20.1
ICD-10 Finland
Hallux valgus (acquired)
2.3
6.6
52
242
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
3.9
6.6
19
50
J01MA12
ATC
levofloxacin; systemic
1.9
6.6
97
568
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
10.2
6.6
12
12
SPAT1240
SPAT
Therapeutic discussion
2.2
6.6
58
283
N30.0
ICD-10 Finland
Acute cystitis
1.9
6.5
91
524
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
3.3
6.5
24
75
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
3.5
6.5
22
65
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
6.4
136
885
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
2.7
6.4
33
125
NBL22
NOMESCO Finland
Myotomy, tenotomy or excision of tendon of upper arm
14.5
6.4
10
7
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.3
6.4
49
225
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
6.7
6.4
15
23
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
6.7
6.4
15
23
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.3
6.4
46
206
EB1VA, ,
NOMESCO Finland
1.8
6.3
103
621
NB1AD
NOMESCO Finland
Shoulder CT examination
5.6
6.3
17
31
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
6.3
196
1405
R20.2
ICD-10 Finland
Paraesthesia of skin
2.6
6.3
37
150
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.6
6.3
35
138
C02AC05
ATC
moxonidine; oral
3.0
6.3
28
98
C09DA01
ATC
losartan and diuretics; oral
2.0
6.3
66
344
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.8
6.3
102
615
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
6.3
83
469
WX290
NOMESCO Finland
Other blockage of nerve
1.6
6.3
250
1901
7290A
ICD-9 Finland
Other disorders of soft tissues, Rheumatism, unspecified and fibrositis
+∞
6.3
6
*
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.5
6.3
38
157
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
3.0
6.2
27
93
Z01.2
ICD-10 Finland
Dental examination
1.6
6.2
243
1837
G54.0
ICD-10 Finland
Brachial plexus disorders
4.0
6.2
17
43
R01AD08
ATC
fluticasone; nasal
1.7
6.2
155
1053
XA402
NOMESCO Finland
ENMG
6.4
6.2
15
24
C10AA04
ATC
fluvastatin; oral
2.3
6.2
45
202
N06AX26
ATC
vortioxetine; oral
2.3
6.2
45
202
UJD02
NOMESCO Finland
Gastroscopy
2.8
6.2
31
116
R05FB02
ATC
cough suppressants and expectorants; systemic
1.6
6.2
194
1394
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
6.2
70
375
KMAK, ,
NOMESCO Finland
1.6
6.2
273
2122
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
6.2
144
961
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.7
6.2
137
903
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.0
6.1
27
94
WX002
NOMESCO Finland
Sedation and analgesia
1.8
6.1
100
604
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
3.2
6.1
24
78
M02AA15
ATC
diclofenac; topical
2.4
6.1
42
184
J01DA06
ATC
[U] cefuroxime
1.9
6.1
81
458
Z00.0
ICD-10 Finland
General medical examination
1.8
6.1
98
589
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
6.1
148
998
A46
ICD-10 Finland
Erysipelas
1.9
6.1
78
436
SGB10
NOMESCO Finland
Root filling of tooth with one root canal
2.0
6.1
68
363
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
6.1
6.0
15
25
G47.3
ICD-10 Finland
Sleep apnoea
1.7
6.0
124
800
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.7
6.0
134
883
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
6.0
185
1322
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
160
748
2.59
21.17
1.4
1.2
7.73
19.80
u/ml
1.63
73
269
170
826
2.52
20.68
1.5
1.3
31.63
34.57
iu/ml
0.14
62
279
451
3482
2.48
16.85
6.4
3.9
11.36
12.41
mm/h
0.97
437
3232
199
1143
2.15
15.65
2.9
2.6
321.01
340.99
umol/l
2.27
183
1005
379
2775
2.12
15.31
6.3
4.4
6.78
6.66
mmol/l
0.56
363
2628
310
2143
1.99
14.27
2.8
2.6
—
—
estimate
—
0
0
341
2474
1.96
13.23
5.8
3.6
0.00
0.00
estimate
-0.00
65
525
342
2503
1.93
12.70
5.8
3.6
0.05
0.01
estimate
0.38
63
497
335
2453
1.90
12.22
5.8
3.6
0.00
0.00
estimate
-0.00
65
511
173
1021
2.00
12.11
5.6
3.8
1.02
1.02
kg/l
0.22
117
682
324
2359
1.88
11.90
9.5
6.7
1.22
1.21
mmol/l
0.56
305
2035
295
2092
1.86
11.71
8.6
6.1
1.21
1.21
mmol/l
0.29
287
1927
359
2724
1.88
11.33
10.0
10.0
4.26
4.11
e9/l
0.64
327
2380
255
1747
1.84
11.14
5.0
3.4
40.23
38.44
ng/l
0.05
190
1203
389
3053
1.89
10.75
6.2
4.2
101.40
2176.36
e6/l
—
5
47
294
2131
1.79
10.43
15.4
12.5
1.21
1.22
inr
0.07
253
1740
208
1361
1.84
10.36
2.3
2.0
156.26
222.29
u/l
0.57
198
1278
289
2094
1.78
10.18
2.2
2.0
101.03
95.29
pmol/l
1.23
172
1091
446
3701
1.99
9.92
9.5
8.0
79.01
79.57
u/l
0.10
432
3517
262
1890
1.72
9.01
5.7
3.6
0.02
0.02
estimate
0.04
53
429
527
4722
2.81
8.88
21.7
13.7
20.71
24.37
mg/l
1.96
467
3798
213
1455
1.75
8.88
3.2
2.4
62.32
68.64
u/l
0.32
208
1356
161
1014
1.82
8.84
2.8
2.4
4.53
6.40
e6/l
1.21
152
920
183
1198
1.78
8.83
2.4
2.1
2.74
2.92
mg/l
0.47
165
1021
155
972
1.82
8.60
1.7
1.5
0.98
1.34
mg/l
1.00
127
762
292
2193
1.69
8.48
2.8
2.4
73.37
78.03
nmol/l
2.51
277
1985
114
661
1.91
8.05
2.4
2.5
23.46
22.95
%
0.15
104
624
128
774
1.85
7.93
2.8
2.4
13.29
13.18
umol/l
0.07
121
730
227
1617
1.68
7.90
4.4
4.1
7.83
7.66
mg/mmol
0.03
162
991
231
1656
1.67
7.82
3.8
3.3
7.66
7.59
mmol/l
0.08
208
1403
121
722
1.86
7.80
2.5
2.4
2.37
2.32
g/l
0.50
114
673
193
1334
1.68
7.43
3.7
3.1
1759.88
1230.49
ng/l
0.87
174
1136
94
526
1.94
7.34
10.1
7.3
12.54
12.42
kpa
0.09
94
508
94
526
1.94
7.34
10.1
7.3
4.99
5.14
kpa
0.99
94
506
224
1613
1.65
7.34
3.6
3.1
30.77
32.33
u/l
0.27
214
1537
166
1117
1.69
7.01
2.2
2.2
—
—
—
0
0
293
2277
1.60
6.89
3.1
2.9
110.16
122.56
ug/l
0.60
283
2117
442
3807
1.75
6.84
5.1
4.3
14.84
14.74
pmol/l
0.41
422
3489
189
1329
1.64
6.68
6.1
3.7
0.00
0.00
estimate
0.50
59
491
91
521
1.89
6.62
10.3
7.3
0.99
1.09
mmol/l
0.11
79
428
82
456
1.93
6.50
3.1
3.3
2.03
1.87
mmol/l
0.12
74
385
348
2840
1.59
6.47
3.1
2.9
—
—
—
0
0
118
741
1.75
6.33
1.5
1.7
1103.90
1187.38
nmol/l
0.55
102
538
32
121
2.74
6.26
1.2
1.2
—
—
—
0
0
204
1486
1.58
6.13
3.9
3.0
26.14
88.95
e6/l
0.79
175
1122
90
531
1.83
5.94
1.9
1.7
—
—
—
0
0
77
437
1.88
5.74
1.8
2.2
394.84
386.47
nmol/l
0.10
68
408
29
111
2.70
5.56
1.2
1.1
—
—
—
0
0
18
52
3.54
5.49
1.1
1.3
—
—
—
0
0
150
1050
1.58
5.21
1.4
1.3
1.73
1.55
u/ml
0.07
46
279
84
508
1.77
5.09
1.9
1.8
—
—
—
0
0
176
1284
1.54
5.07
3.6
2.9
0.29
0.42
e6/l
0.55
146
931
44
215
2.14
4.98
1.5
1.3
—
—
—
0
0
30
124
2.50
4.97
1.3
1.2
—
—
—
0
0
266
2124
1.48
4.92
5.2
4.7
35.39
35.85
g/l
0.66
257
2000
111
731
1.65
4.92
2.0
1.9
—
—
—
0
0
216
1655
1.50
4.91
4.5
3.0
—
—
—
0
0
28
114
2.53
4.79
1.2
1.1
—
—
—
0
0
117
788
1.61
4.73
3.2
2.7
1.56
1.15
e6/l
0.56
73
416
217
1674
1.48
4.73
2.9
3.6
2.35
2.36
mmol/l
0.50
204
1532
493
4510
1.75
4.63
6.6
5.2
1.80
1.92
mu/l
1.76
476
4149
50
264
1.98
4.62
6.2
6.0
24.48
24.29
mmol/l
0.16
50
251
56
308
1.91
4.60
1.5
1.5
—
—
—
0
0
53
287
1.93
4.55
15.0
9.0
94.46
93.48
%
0.94
53
287
45
230
2.04
4.54
4.1
3.7
1.02
1.02
ratio
0.29
40
220
126
874
1.57
4.49
4.2
3.6
197.46
494.32
ng/l
1.47
98
685
62
358
1.82
4.38
1.5
1.5
—
—
—
0
0
178
1338
1.48
4.35
1.6
1.6
25.11
20.83
nmol/l
0.44
162
1131
116
798
1.57
4.27
1.6
1.5
—
—
—
0
0
51
283
1.88
4.09
2.4
2.5
17.45
20.52
au/ml
—
6
26
22
89
2.53
3.84
3.3
3.2
9.60
8.88
pmol/l
0.12
22
89
58
342
1.78
3.84
3.8
2.8
61.12
63.25
ml/min/173m2
0.15
26
147
38
197
2.00
3.72
1.4
1.4
—
—
—
0
0
496
4605
1.65
3.64
8.0
6.0
41.02
38.92
mmol/mol
4.71
479
4302
78
518
1.59
3.32
9.0
6.2
—
—
—
0
0
46
267
1.79
3.23
2.9
3.5
24.29
24.16
mmol/l
0.08
46
262
14
49
2.90
3.21
1.4
1.3
—
—
—
0
0
14
49
2.90
3.21
1.4
1.3
—
—
—
0
0
21
92
2.33
3.14
1.2
1.7
5011.54
13457.87
e6/l
0.93
13
69
14
50
2.85
3.10
1.4
1.3
—
—
—
0
0
38
211
1.86
3.08
1.4
1.6
0.27
0.30
mg/l
0.10
18
98
130
977
1.43
3.06
2.2
3.0
2.44
2.45
mmol/l
0.71
120
890
90
630
1.51
3.04
6.0
5.0
1.05
1.03
mmol/l
0.22
85
588
77
521
1.55
3.03
2.4
2.5
8.32
8.25
umol/l
0.01
72
462
58
367
1.65
3.01
2.0
1.9
—
—
—
0
0
42
247
1.76
2.85
5.1
3.5
1.82
2.25
mmol/l
0.25
28
187
14
54
2.63
2.72
1.4
1.3
—
—
—
0
0
19
86
2.25
2.66
1.3
1.1
1.27
3.36
u/ml
—
9
38
366
3281
1.33
2.64
3.7
3.2
49.25
49.38
u/l
0.01
351
3088
14
55
2.58
2.63
1.4
1.3
—
—
—
0
0
14
55
2.58
2.63
1.4
1.3
—
—
—
0
0
99
727
1.44
2.63
3.2
2.8
3.23
2.99
e6/l
0.09
56
355
173
1397
1.34
2.60
5.4
3.0
4.40
0.00
estimate
0.49
57
396
34
195
1.79
2.53
1.4
1.8
1.71
1.55
g/l
0.45
27
174
532
5104
1.77
2.51
15.7
11.3
25.88
25.60
u/l
0.12
526
4951
41
254
1.66
2.34
15.3
9.7
16.64
15.65
%
1.55
41
245
23
119
1.97
2.34
1.3
1.2
—
—
—
0
0
544
5268
1.97
2.27
32.0
21.4
255.15
253.98
e9/l
0.17
539
5150
544
5270
1.96
2.24
31.9
21.4
4.48
4.48
e12/l
0.05
538
5138
23
122
1.92
2.19
1.3
1.4
—
—
—
0
0
9
31
2.93
2.08
1.7
1.2
76.67
83.03
umol/l
—
9
31
10
37
2.73
2.08
2.0
3.2
525.50
1147.32
mg
—
10
37
492
4677
1.41
1.99
19.0
13.7
79.89
80.87
ml/min/173m2
0.51
466
4330
37
234
1.62
1.98
2.4
1.9
—
—
—
0
0
25
142
1.80
1.96
1.6
1.4
243.54
294.83
ug/g
0.51
13
81
494
4702
1.41
1.96
6.1
4.9
6.16
5.89
mmol/l
3.13
471
4316
5
11
4.58
1.94
1.0
2.5
0.97
1.16
ug/l
—
5
11
6
16
3.78
1.94
1.7
2.5
40.17
42.69
g/l
—
6
16
32
197
1.66
1.91
2.0
1.8
—
—
—
0
0
9
34
2.67
1.87
1.1
1.1
107.33
109.29
pmol/l
—
9
34
38
246
1.58
1.87
1.6
1.7
—
—
—
0
0
31
191
1.66
1.85
2.1
1.9
7.99
7.02
iu/ml
0.08
13
41
53
371
1.47
1.84
4.1
3.6
87.03
82.24
ng/l
0.18
47
329
8
30
2.69
1.73
1.1
1.2
—
—
—
0
0
8
30
2.69
1.73
1.1
1.2
—
—
—
0
0
7
24
2.94
1.72
1.6
1.4
6.16
6.76
mmol/l
—
7
24
60
437
1.42
1.70
2.2
2.2
0.21
0.22
g/l
0.35
54
416
28
173
1.65
1.67
2.7
1.6
—
—
—
0
0
22
127
1.76
1.66
1.2
1.2
—
—
—
0
0
8
31
2.60
1.66
1.0
1.0
—
—
—
0
0
18
98
1.86
1.63
1.4
1.2
603.94
515.79
mg/l
0.20
18
92
124
1016
1.28
1.63
1.7
1.7
413.58
18256242.48
pmol/l
0.69
112
860
56
407
1.42
1.62
2.3
2.0
—
—
—
0
0
58
427
1.40
1.56
2.7
2.1
59.51
41.92
u/l
0.25
47
356
45
318
1.45
1.52
3.0
3.2
111.62
197.82
ng/l
2.20
39
287
15
80
1.90
1.46
1.1
1.2
—
—
—
0
0
15
80
1.90
1.46
1.1
1.2
—
—
—
0
0
7
28
2.52
1.45
1.0
1.2
—
—
—
0
0
13
66
1.99
1.44
1.2
1.6
—
—
—
0
0
9
39
2.33
1.43
1.2
2.7
2.30
5.99
umol/l
—
9
26
72
559
1.33
1.41
1.9
1.8
1.55
1.43
%
0.98
66
490
25
158
1.61
1.40
1.4
1.6
0.11
0.13
iu/ml
—
7
20
502
4840
1.34
1.38
6.0
5.0
4.68
4.72
mmol/l
0.39
483
4516
10
47
2.15
1.34
1.2
1.2
—
—
—
0
0
17
99
1.74
1.28
2.3
1.5
—
—
—
0
0
23
147
1.59
1.25
1.2
1.4
129.29
231.25
miu/ml
—
7
65
6
25
2.41
1.24
1.7
2.3
138.50
142.64
ng/l
—
6
25
508
4920
1.33
1.23
6.8
5.7
2.68
2.76
mmol/l
1.52
490
4576
19
117
1.65
1.19
1.7
2.9
0.00
2.76
index
—
8
71
8
38
2.12
1.19
1.3
1.1
—
—
—
0
0
14
79
1.79
1.18
1.4
1.5
—
—
—
0
0
5
20
2.51
1.15
1.2
1.2
—
—
—
0
0
5
20
2.51
1.15
1.2
1.2
—
—
—
0
0
479
4613
1.26
1.15
5.1
4.2
1.40
1.28
mmol/l
2.28
454
4245
19
119
1.62
1.13
1.8
2.2
1037.03
7746.67
u/l
—
7
49
20
128
1.58
1.10
2.0
1.9
0.24
0.25
g/l
0.30
20
122
12
202
0.59
1.03
1.1
1.2
1.54
1.58
g/l
0.12
12
202
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
29
205
1.44
1.03
1.5
3.6
30.18
1470.85
u/ml
1.24
22
183
145
1272
1.19
1.00
5.5
5.2
2.26
2.35
ug/l
0.09
133
1147
20
132
1.53
0.98
2.0
1.8
1.20
1.25
g/l
0.25
20
126
0
29
0.00
0.98
0.0
1.1
—
1534.45
—
0
29
10
54
1.87
0.97
1.7
1.9
15.60
28.33
mg/l
—
5
19
11
62
1.79
0.94
3.2
2.7
3.88
3.99
mmol/l
0.37
11
62
11
62
1.79
0.94
3.2
2.7
108.00
105.61
mmol/l
1.34
11
62
11
62
1.79
0.94
3.2
2.7
1.22
1.19
mmol/l
1.62
11
62
67
549
1.25
0.92
3.3
4.8
2.87
35.47
ug/l
1.42
57
446
6
28
2.15
0.91
1.3
1.1
—
—
—
0
0
6
28
2.15
0.91
2.7
3.6
505.83
896.71
u/ml
—
6
28
13
204
0.63
0.87
1.2
1.2
0.83
0.91
g/l
0.51
13
204
16
104
1.55
0.85
1.1
1.4
—
—
—
0
0
495
4820
1.22
0.82
5.9
4.9
1.48
1.50
mmol/l
0.60
472
4465
19
130
1.48
0.82
1.7
2.0
4.03
3.59
g/l
0.46
19
125
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
20
140
1.44
0.78
1.4
3.4
1.51
2.40
ratio
—
10
80
19
133
1.44
0.74
1.6
2.0
3.93
5.14
iu/l
—
6
57
5
25
2.01
0.73
1.2
1.3
—
—
—
0
0
5
25
2.01
0.73
1.2
1.3
—
—
—
0
0
9
56
1.62
0.72
1.2
1.6
—
—
—
0
0
7
40
1.76
0.71
1.1
1.1
—
—
—
0
0
22
160
1.39
0.71
3.2
2.6
—
—
—
0
0
12
77
1.57
0.69
1.2
1.3
—
—
—
0
0
38
303
1.27
0.68
5.1
2.9
39.57
83.24
u/ml
0.51
38
293
11
70
1.58
0.65
1.5
1.7
—
—
—
0
0
8
127
0.62
0.64
1.1
1.3
—
—
—
0
0
8
49
1.64
0.62
6.9
3.5
—
—
—
0
0
8
50
1.61
0.61
1.0
1.7
36.18
44.27
ug/l
—
8
50
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
18
131
1.39
0.60
2.3
2.4
0.21
0.36
iu/ml
—
10
72
224
2100
1.11
0.58
2.1
1.9
1.33
1.32
mmol/l
0.08
197
1760
6
35
1.72
0.58
1.2
1.0
—
—
—
0
0
14
98
1.44
0.57
1.2
1.2
—
—
—
0
0
6
37
1.63
0.55
1.2
1.1
270.33
287.39
mg/l
—
6
31
16
116
1.39
0.55
1.6
1.5
—
—
—
0
0
11
74
1.50
0.53
1.0
1.1
1.37
1.45
g/l
0.38
11
67
20
154
1.31
0.49
1.7
1.5
—
—
—
0
0
7
45
1.56
0.49
1.0
1.4
—
—
—
0
0
7
45
1.56
0.49
2.0
1.4
—
—
—
0
0
20
155
1.30
0.47
1.2
1.6
999.65
945.24
mu/l
0.08
14
126
41
348
1.19
0.46
1.2
1.2
191.85
156.60
u/ml
0.21
16
140
16
121
1.33
0.44
4.7
3.0
8.44
8.13
kpa
0.32
16
121
5
31
1.62
0.43
1.2
1.0
—
—
—
0
0
16
122
1.32
0.42
1.2
1.1
—
5.98
—
0
19
5
32
1.57
0.42
1.2
1.0
—
—
—
0
0
5
32
1.57
0.42
1.2
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
372.33
—
0
9
8
60
1.34
0.40
1.0
1.1
—
—
—
0
0
16
124
1.30
0.39
1.6
1.6
—
—
—
0
0
9
66
1.37
0.38
1.4
1.9
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
111
1028
1.10
0.37
5.3
4.5
22.55
21.27
%
0.46
65
505
66
594
1.13
0.37
5.5
4.8
32.96
32.73
%
0.06
52
388
36
415
0.86
0.35
1.9
1.8
3.34
3.44
mmol/l
0.15
25
304
90
828
1.10
0.34
1.5
1.5
—
—
—
0
0
51
571
0.88
0.34
2.3
2.0
3.52
3.42
ratio
0.22
42
460
10
74
1.36
0.32
1.4
1.8
—
—
—
0
0
18
152
1.19
0.24
2.2
2.7
1.64
1.52
mg/l
0.24
18
137
20
171
1.18
0.23
2.3
2.0
—
—
—
0
0
5
39
1.28
0.23
1.6
2.1
—
—
—
0
0
7
94
0.74
0.22
2.0
1.8
192.00
210.11
pmol/l
—
7
89
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
5
41
1.22
0.22
1.2
1.1
—
—
—
0
0
5
41
1.22
0.22
1.6
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
19
164
1.16
0.20
1.6
1.5
—
—
—
0
0
24
212
1.14
0.20
1.0
1.1
—
—
—
0
0
13
109
1.20
0.18
1.5
1.4
—
—
—
0
0
46
491
0.93
0.15
3.3
3.1
—
—
—
0
0
7
86
0.81
0.14
1.0
1.1
—
434.29
—
0
7
18
201
0.89
0.13
1.4
1.6
—
—
—
0
0
11
94
1.17
0.13
1.6
1.4
—
—
—
0
0
9
110
0.82
0.13
1.9
1.4
—
—
—
0
0
5
45
1.11
0.10
2.8
2.5
—
—
—
0
0
6
56
1.07
0.08
2.2
4.4
12.38
40.54
u/ml
—
6
56
6
72
0.83
0.07
3.2
5.5
396.50
344.67
umol/l
—
6
61
6
73
0.82
0.07
3.3
2.7
—
661.40
—
0
5
17
157
1.09
0.07
2.2
1.9
—
—
—
0
0
12
113
1.06
0.02
4.6
3.8
19.87
2578.84
u/ml
0.63
12
106
12
116
1.04
0.00
1.6
1.5
—
—
—
0
0
10
99
1.01
0.00
1.4
1.4
—
—
—
0
0
77
771
1.00
0.00
3.9
3.1
0.70
0.75
ug/l
0.33
57
504
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
98.00
—
0
5
5
51
0.98
-0.00
2.0
1.1
0.87
1.37
nmol/l
—
5
46
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
51
0.98
-0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
36.83
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
-0.00
3.3
2.6
17.81
16.06
%
—
8
80
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
60
1.00
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
-0.00
1.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
2.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_CHRONSYNOVITISHANDWRIST and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_CHRONSYNOVITISHANDWRIST | 1.108 [0.94, 1.3] | 0.21 |
| Birth year | 0.995 [0.99, 1.0] | 0.231 |
During the follow-up period (1.1.1998 — 31.12.2019), 269 out of 1878 females with M13_CHRONSYNOVITISHANDWRIST died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_CHRONSYNOVITISHANDWRIST | 1.158 [0.99, 1.36] | 0.074 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 238 out of 1368 males with M13_CHRONSYNOVITISHANDWRIST died.
Mortality risk
Mortality risk for people of age
years, who have M13_CHRONSYNOVITISHANDWRIST.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.098% | 0.258% |
| 5 | 0.652% | 1.328% |
| 10 | 1.581% | 3.134% |
| 15 | 2.973% | 5.697% |
| 20 | 5.195% | 10.039% |
Relationships between endpoints
↥Index endpoint: M13_CHRONSYNOVITISHANDWRIST – Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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