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Mandibular retrognathia

EFO Endpoint Browser PheWeb

K11_MN_RETRGN

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — K07.13
  • Hospital discharge: ICD-10 — K07.13
  • Cause of death: ICD-10 — K07.13

3 out of 7 registries used, show all original rules.

3051

4. Check minimum number of events

None

3051

5. Include endpoints

None

3051

6. Filter based on genotype QC (FinnGen only)

2743

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 54236 28196 25988
Only index persons 47897 25173 22724
Unadjusted period prevalence (%)
Whole population 0.77 0.81 0.73
Only index persons 0.90 0.93 0.87
Median age at first event (years)
Whole population 12.06 12.44 11.60
Only index persons 12.73 13.25 12.15

-FinnGen-

Key figures

All Female Male
Number of individuals 2743 1926 817
Unadjusted period prevalence (%) 0.59 0.68 0.37
Median age at first event (years) 35.76 34.44 38.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2880
Matched controls
28713
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
6.6
319.0
591
1082
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
5.8
317.4
699
1508
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
94.6
307.7
298
35
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
18.2
307.7
483
315
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
13.6
307.7
1061
1179
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
9.8
307.7
465
552
SXC05
NOMESCO Finland
Other oral or dental procedure
6.5
307.7
986
2136
K07.13
ICD-10 Finland
Retrognaty, mandibular
+∞
307.7
2880
*
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
77.3
307.7
175
24
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
18.4
307.7
1233
1124
EB1MA
NOMESCO Finland
Cephalometry with X-ray
16.4
307.7
1074
1005
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
11.2
307.7
1187
1692
EEC05
NOMESCO Finland
Le Fort I osteotomy
101.3
307.7
276
30
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
9.4
307.7
728
996
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
20.1
307.7
1065
815
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
25.4
307.7
379
170
SAA04
NOMESCO Finland
Special examination of mouth
11.5
307.7
1051
1362
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
48.2
307.7
190
42
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
12.0
307.7
923
1085
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
5.8
307.7
724
1561
K07.24
ICD-10 Finland
Open bite
23.7
307.7
511
259
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
14.2
307.7
783
734
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
15.7
307.7
463
347
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
7.1
307.7
616
1064
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
19.4
307.7
1251
1094
K07.23
ICD-10 Finland
Deep bite
23.7
307.7
1230
875
SJC10
NOMESCO Finland
Orthodontic band in one tooth
18.1
307.7
1008
830
K07.60
ICD-10 Finland
Snapping jaw
7.6
307.7
640
1038
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
6.7
307.7
630
1151
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
172.7
307.7
194
12
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
596.7
307.7
1060
28
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
6.5
307.7
1090
2465
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
17.8
307.7
799
605
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
12.1
307.7
688
724
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
16.2
307.7
1042
968
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
17.6
307.7
722
535
SBB10
NOMESCO Finland
Dental impressions
19.7
307.7
1908
2596
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
31.9
307.7
276
95
K07.10
ICD-10 Finland
Asymmetry of jaw
55.9
307.7
218
42
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
20.3
307.7
1168
934
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
11.4
307.7
550
583
K07.14
ICD-10 Finland
Retrognaty, maxillary
30.6
305.8
203
71
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
5.9
296.1
625
1292
EBB10
NOMESCO Finland
Insertion of dental implant
19.5
289.7
230
127
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
6.2
259.4
499
939
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
12.9
256.1
256
216
SAA03
NOMESCO Finland
Extended examination of mouth
4.0
255.0
2079
11254
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
51.1
252.6
146
30
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
7.2
239.0
385
603
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
61.7
233.3
130
22
EBB15
NOMESCO Finland
Insertion of dental implant abutment
23.7
208.2
151
67
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
33.9
203.0
130
40
WZC00
NOMESCO Finland
Treatment plan or consultation
3.1
190.8
1678
8904
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
15.7
186.7
164
110
SPC20
NOMESCO Finland
Implant borne crown
23.3
183.9
134
60
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
12.8
182.4
181
150
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
55.5
179.5
102
19
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
45.0
161.6
96
22
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
4.7
161.1
421
1019
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
13.6
159.1
151
116
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.8
156.8
1747
10141
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
45.1
155.0
92
21
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
10.1
141.0
163
169
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
4.4
121.3
333
831
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.7
117.1
427
1304
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
9.9
114.5
134
141
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
19.4
113.6
89
47
SXC03
NOMESCO Finland
Other oral or dental procedure
14.3
113.4
104
75
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
7.2
113.3
173
252
SJE90
NOMESCO Finland
Orthodontic finishing
12.2
109.0
110
93
EB1WA, ,
NOMESCO Finland
16.4
107.0
91
57
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
7.8
105.2
150
202
EB1S1
NOMESCO Finland
Photography of teeth
10.4
100.7
113
112
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.2
100.2
292
759
K00.00
ICD-10 Finland
Hypodontia
6.1
98.7
176
301
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
12.7
91.5
90
73
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
6.1
91.2
163
279
OIKK, ,
NOMESCO Finland
3.3
90.8
388
1301
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
34.1
89.3
57
17
EB1TW
NOMESCO Finland
3D modelling of dentition
20.7
88.0
67
33
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
29.5
86.9
58
20
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
14.5
86.0
78
55
K01.0
ICD-10 Finland
Embedded teeth
5.0
84.5
191
405
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
5.3
81.9
172
342
OIKAK, ,
NOMESCO Finland
28.9
80.4
54
19
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.6
79.3
541
2332
R06.5
ICD-10 Finland
Mouth breathing
3.0
79.0
389
1412
SPB20
NOMESCO Finland
Temporary bridge
19.1
78.6
62
33
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
13.3
77.5
74
57
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
6.1
74.8
132
223
G47.3
ICD-10 Finland
Sleep apnoea
2.3
72.7
705
3550
OIKH, ,
NOMESCO Finland
3.3
71.4
288
927
SJB30
NOMESCO Finland
Extraoral traction arrangements and operation instruction, removable appliance
5.4
71.2
143
273
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
3.2
70.3
302
1010
OIKNV, ,
NOMESCO Finland
11.5
69.8
73
65
SPC10
NOMESCO Finland
Standard dental crown
7.4
68.9
101
140
EBA10
NOMESCO Finland
Operative extraction of tooth
2.2
68.0
700
3601
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.7
67.2
229
661
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
10.6
65.6
72
69
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
16.4
64.9
55
34
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
80.7
63.2
71
9
OIKON, ,
NOMESCO Finland
8.3
63.1
84
104
EDC30
NOMESCO Finland
Genioplasty
165.7
62.1
65
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.9
60.1
306
1125
OIKAL, ,
NOMESCO Finland
4.0
58.8
177
468
OIKKK, ,
NOMESCO Finland
10.3
57.2
64
63
SJC20
NOMESCO Finland
Extraoral traction appliance arrangement incl. patient instructions
6.0
50.7
91
156
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
11.2
50.1
53
48
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
8.1
49.8
67
84
SAA02
NOMESCO Finland
Basic examination of mouth
2.1
49.4
2388
20005
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
7.5
47.8
69
94
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
6.9
46.5
72
106
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
6.4
46.4
77
122
OIKPU, ,
NOMESCO Finland
8.7
46.4
59
69
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
3.1
45.4
197
659
EMAK, ,
NOMESCO Finland
3.4
44.4
170
527
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
9.0
43.6
54
61
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
7.4
43.1
63
87
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
42.9
1021
6815
OIKJA, ,
NOMESCO Finland
5.8
42.4
78
137
SPC08
NOMESCO Finland
Implant crown
11.8
40.2
41
35
K07.4
ICD-10 Finland
Malocclusion, unspecified
3.8
39.1
120
321
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
2.9
39.1
191
683
G50.1
ICD-10 Finland
Atypical facial pain
5.1
38.4
82
165
ECA70
NOMESCO Finland
Regenerative periodontal surgery or gingival graft
12.9
38.2
37
29
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
4.6
37.3
90
201
OIKVA, ,
NOMESCO Finland
3.1
36.7
160
536
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
36.2
2340
20089
K07.61
ICD-10 Finland
Cracking jaw joint
3.4
35.7
133
405
OIKRE, ,
NOMESCO Finland
5.1
34.5
73
146
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.1
34.1
148
495
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.6
33.6
1184
8628
WYA10
NOMESCO Finland
Emergency care or similar visit
2.2
33.0
291
1376
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
10.7
33.0
36
34
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
3.5
32.9
115
336
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
5.7
32.9
61
108
EEC02
NOMESCO Finland
Rapid expansion of maxilla
117.7
32.7
35
*
SPF40
NOMESCO Finland
Removal and reattachment of crown or small bridge
5.7
31.6
59
105
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
6.0
31.6
56
95
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
8.3
31.1
41
50
J01CE02
ATC
phenoxymethylpenicillin; oral
1.6
29.6
1999
16768
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.6
29.6
174
685
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
3.5
29.5
104
306
WX704
NOMESCO Finland
Intubation
2.2
29.0
257
1217
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
6.4
29.0
48
76
EFB50
NOMESCO Finland
Orthodontic procedure connected with ortognathic surgery
80.7
28.7
32
*
WZA90
NOMESCO Finland
Other medical or dental certificate
1.6
28.6
819
5617
EBA40
NOMESCO Finland
Extraction of apex of root of tooth
5.6
28.4
54
98
SPAT1324
SPAT
Screening procedure
1.7
28.1
607
3867
ZXA10
NOMESCO Finland
Bilateral
1.8
27.5
445
2605
ZXX03
NOMESCO Finland
Extent of procedure, 3 units
7.9
26.3
36
46
SAALT, ,
NOMESCO Finland
3.1
25.4
105
341
ECA55
NOMESCO Finland
Complicated periodontal flap surgery
8.1
24.7
33
41
OIKTA, ,
NOMESCO Finland
6.3
24.4
41
66
SPA02
NOMESCO Finland
Preparation for dental prosthetics
3.2
24.2
99
320
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
24.2
313
1702
F45.8
ICD-10 Finland
Other somatoform disorders
2.0
23.9
284
1500
SPAT1263
SPAT
Sampling
1.5
23.5
1174
9033
T84.62
ICD-10 Finland
Osteitis associated with dental implants
9.1
22.9
28
31
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
65.3
22.8
26
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
22.6
677
4652
OIKLI, ,
NOMESCO Finland
9.4
22.6
27
29
SXB10
NOMESCO Finland
Removal of attachments and rails from moth
7.5
22.4
32
43
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
43.5
21.4
26
6
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
21.3
605
4098
SCD01
NOMESCO Finland
Removal of biofilm and supragingival calculus, short
3.6
21.2
69
193
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
21.0
754
5386
WX725
NOMESCO Finland
Noninvasive ventilation
2.3
21.0
166
749
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.6
21.0
688
4817
SPC25
NOMESCO Finland
Other demanding attachment of prosthodontic crown
17.9
20.8
32
18
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
20.7
1395
11288
EGC30
NOMESCO Finland
Prosthetic replacement of mandibular joint
30.2
20.5
27
9
SDA03
NOMESCO Finland
Periodontal treatment
1.4
20.0
1216
9632
EAB10
NOMESCO Finland
Excision and repair of frenum of lip
7.6
19.9
28
37
WX720
NOMESCO Finland
Own respiration
2.4
19.5
142
618
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
19.1
201
1014
TEG00
NOMESCO Finland
Punction of mandibular joint
18.2
19.0
29
16
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
15.9
18.7
30
19
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
27.9
18.7
25
9
K07.68
ICD-10 Finland
Other disorders of the jaw joint
4.5
18.6
45
101
N03AX16
ATC
[U] pregabalin
1.6
18.1
494
3303
EDW99
NOMESCO Finland
Other operation on mandible
16.6
17.8
28
17
SPC01
NOMESCO Finland
Fixed dental crown
3.6
17.8
57
158
TEG10
NOMESCO Finland
Injection of diagnostic or therapeutic substance into mandibular joint
13.7
17.7
30
22
K07.33
ICD-10 Finland
Crowding of tooth or teeth
5.3
17.7
35
66
SCA01
NOMESCO Finland
Preventive oral health care, short
1.4
17.6
1232
9934
J34.2
ICD-10 Finland
Deviated nasal septum
2.2
17.5
148
686
EBA00
NOMESCO Finland
Extraction of tooth
1.4
17.4
1154
9213
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
42.1
17.3
21
5
Z50.1
ICD-10 Finland
Other physical therapy
2.3
17.0
124
540
K06.00
ICD-10 Finland
Local gingivore traction
2.9
17.0
80
281
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.4
16.9
1032
8107
XX2XT
NOMESCO Finland
Other injection with other radiological guidance
6.9
16.9
26
38
K07.00
ICD-10 Finland
Macrognatia (hyperplasia) of the upper jaw
25.7
16.9
23
9
K01.17
ICD-10 Finland
Retained molar with obstruction in the lower jaw
2.1
16.9
160
777
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
3.8
16.8
51
136
J01FF01
ATC
clindamycin; systemic
1.5
16.7
620
4427
M79.1
ICD-10 Finland
Myalgia
1.6
16.6
452
3016
SCA02
NOMESCO Finland
Preventive oral health care
1.5
16.6
532
3684
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
16.5
239
1344
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
7.0
16.5
25
36
SPF10
NOMESCO Finland
Demanding reparation of dental prosthesis
5.6
16.4
31
56
SPA30
NOMESCO Finland
Grinding of a single crown and bridge pillar or a single post and crown
3.7
16.3
51
139
EB1KA
NOMESCO Finland
Partial (restricted area) panoramic tomography of teeth or jaw
4.8
15.8
35
73
YEA05
NOMESCO Finland
Excision of gingival or connective tissue for transplantation
60.2
15.7
18
*
K07.0
ICD-10 Finland
Major anomalies of jaw size
33.4
15.7
20
6
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
12.3
15.3
27
22
EGA00
NOMESCO Finland
Arthroscopy of mandibular joint
11.3
15.2
28
25
-1, ,
NOMESCO Finland
1.4
15.1
1174
9557
A02BC05
ATC
esomeprazole; systemic
1.4
15.0
907
7079
HAMTE, ,
NOMESCO Finland
4.5
14.9
36
81
SPAT1301
SPAT
No procedures
1.4
14.8
766
5813
HMAK, ,
NOMESCO Finland
1.7
14.7
308
1922
ECB05
NOMESCO Finland
Mucogingival remodeling
5.0
14.7
31
62
P01BA02
ATC
hydroxychloroquine; oral
1.9
14.5
196
1078
ZYC01
NOMESCO Finland
Remote contact by phone
1.8
14.4
203
1132
XX3DW
NOMESCO Finland
Time consuming IT work
1.8
14.2
212
1203
SJC04, ,
NOMESCO Finland
4.9
14.2
31
64
5240A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Major anomalies of jaw size
19.2
14.2
21
11
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
14.4
14.0
23
16
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
14.0
944
7488
WX402
NOMESCO Finland
General anaesthesia
1.5
13.9
610
4487
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
13.7
262
1595
L01BA01
ATC
methotrexate; systemic
2.4
13.7
95
405
4344
FHL
Osteotomy and shaping of the lower jaw (jaw deformities)
16.2
13.4
21
13
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
13.4
359
2379
KIP00, ,
NOMESCO Finland
12.8
13.4
23
18
L04AX03
ATC
methotrexate; systemic
1.7
13.3
250
1515
ZXX05
NOMESCO Finland
Extent of procedure, 5 units
10.5
13.2
25
24
SXC06
NOMESCO Finland
Clinical work to produce sleep apnoea splint
5.3
13.2
26
49
OIKIN, ,
NOMESCO Finland
3.6
13.2
43
121
SCD02
NOMESCO Finland
Removal of biofilm and/or supragingival calculus
4.1
13.2
35
85
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.3
13.1
100
445
Z01.2
ICD-10 Finland
Dental examination
1.3
13.1
1516
13022
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.8
13.0
189
1063
ECA30
NOMESCO Finland
Excision of lesion of gingiva
4.0
13.0
36
90
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.2
12.8
103
469
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.9
12.8
174
960
P01AB01
ATC
metronidazole; oral, rectal
1.4
12.7
973
7844
UDC00
NOMESCO Finland
Ear microscopy
1.8
12.6
200
1156
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
12.5
267
1674
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
+∞
12.5
12
*
ECU00
NOMESCO Finland
Removal of implant or external fixation device from alveoli
17.3
12.5
19
11
XX3GW
NOMESCO Finland
3D printout, very extensive
130.2
12.4
13
*
XX7LW, ,
NOMESCO Finland
20.1
12.4
18
9
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.3
12.4
92
405
SPF41
NOMESCO Finland
Repair of dental crown, bridge or implant structure, standard
3.2
12.4
47
146
L04AB01
ATC
etanercept; parenteral
2.8
12.4
62
226
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
12.3
480
3441
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.1
12.3
113
543
A02BC03
ATC
lansoprazole; oral
1.4
12.2
533
3907
K07.32
ICD-10 Finland
Displacement of tooth or teeth
5.1
12.2
25
49
SPC09
NOMESCO Finland
Implant crown, demanding
15.9
12.1
19
12
R01AD09
ATC
mometasone; nasal
1.3
12.1
1273
10735
T84.60
ICD-10 Finland
Gingivitis associated with dental implants
4.9
12.1
26
53
SFA00
NOMESCO Finland
Small restoration
1.5
12.1
389
2684
K07.09
ICD-10 Finland
Anomaly in the size of the jaws UNS
21.3
12.0
17
8
Z01.9
ICD-10 Finland
Special examination, unspecified
1.9
11.8
147
788
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
11.7
510
3735
SJD60, ,
NOMESCO Finland
65.0
11.6
13
*
G50.8
ICD-10 Finland
Other disorders of trigeminal nerve
11.1
11.5
21
19
K03.00
ICD-10 Finland
Approximal wear
1.7
11.5
235
1458
K05.30
ICD-10 Finland
Periodontitis complex
1.6
11.5
314
2090
WZC00, ,
SPAT
1.4
11.3
468
3390
PLAK0, ,
NOMESCO Finland
3.4
11.2
40
120
SPA61
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 4 to 6 units
4.7
11.1
25
53
A45
ICPC
General and Unspecified, Observ/health educat/advice/diet
2.5
11.1
71
293
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
11.1
1496
13000
PLAK2, ,
NOMESCO Finland
3.9
11.0
32
83
SPA40
NOMESCO Finland
Precision impression for dental prosthesis
5.7
11.0
20
35
M01AE02
ATC
naproxen; oral, rectal
1.3
10.8
1641
14463
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
11.9
10.8
19
16
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
3.3
10.8
39
118
ECA50
NOMESCO Finland
Periodontal flap surgery
4.0
10.6
29
72
L04AA13
ATC
[U] leflunomide
2.5
10.6
63
251
EDC05
NOMESCO Finland
Segmental osteotomy of mandible
+∞
10.4
10
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
10.3
420
3029
L88
ICPC
Rheumatoid/seropositive arthritis
2.1
10.3
101
498
N02BE01
ATC
paracetamol; systemic, rectal
1.4
10.3
2303
21358
C05AA08
ATC
fluocortolone; rectal, topical
1.6
10.2
249
1612
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
2.8
10.2
49
175
WZC30
NOMESCO Finland
Teaching
1.5
10.2
349
2434
R51.81
ICD-10 Finland
Facial pain NOS
2.3
10.2
72
311
Z3231
NOMESCO Finland
Registered nurse
1.4
10.2
659
5145
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.7
10.2
202
1243
ENC40
NOMESCO Finland
Uvulopalatopharyngoplasty
3.9
10.1
29
75
J02AC01
ATC
fluconazole; systemic
1.3
10.1
1009
8390
ED1AA
NOMESCO Finland
Mandibular X-ray examination
4.3
10.0
25
58
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
40.1
9.9
12
*
C07AA05
ATC
propranolol; systemic
1.4
9.9
548
4171
R01AD58
ATC
fluticasone, combinations; nasal
1.3
9.9
778
6251
N06AX21
ATC
duloxetine; oral
1.5
9.9
296
2008
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
9.8
822
6660
SPAT1153
SPAT
Removal of sutures
1.4
9.8
587
4522
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
9.8
943
7788
N06AX11
ATC
mirtazapine; oral
1.3
9.8
795
6415
SCA04
NOMESCO Finland
Guidance on care of mouth and oral mucosa
8.7
9.7
20
23
SPE00
NOMESCO Finland
Partial denture with metal framework
3.8
9.7
29
77
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.8
9.7
139
780
EG1AD
NOMESCO Finland
CT of mandipular joint
55.0
9.6
11
*
K07.08
ICD-10 Finland
Other specified anomaly in the size of the cores
55.0
9.6
11
*
SFB40
NOMESCO Finland
Filling of four surfaces reproduced outside mouth
4.3
9.5
24
56
SPE90
NOMESCO Finland
Other partial denture
3.3
9.5
35
107
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.8
9.4
129
715
SFA10
NOMESCO Finland
One-surface restoration
1.3
9.4
1644
14634
SFB30
NOMESCO Finland
Indirect three-surface restoration
4.9
9.3
20
41
A07EC01
ATC
sulfasalazine; oral, rectal
1.7
9.3
177
1079
EG1DG
NOMESCO Finland
Very extensive MRI examination of mandibular joint with high intensity magnet
9.5
9.2
18
19
R01AD12
ATC
fluticasone furoate; nasal
1.3
9.2
958
7982
AA40B, ,
NOMESCO Finland
7.7
9.1
20
26
K07
ICD-10 Finland
Dentofacial anomalies [including malocclusion]
3.5
8.9
30
87
ENC30
NOMESCO Finland
Plastic operation of pharynx
3.3
8.8
32
97
SCB01
NOMESCO Finland
Instructions for self-performed oral hygiene, short
2.5
8.8
52
207
SPE05
NOMESCO Finland
Demanding partial denture with metal framework
9.5
8.7
17
18
SAE03, ,
NOMESCO Finland
4.1
8.7
23
56
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.5
8.7
52
209
ZXC60
NOMESCO Finland
Application of heat
2.7
8.6
44
163
A31
ICPC
General and Unspecified, Medical examin/health eval partial
1.9
8.6
114
625
L04AB06
ATC
golimumab; parenteral
3.1
8.6
34
109
K07.6
ICD-10 Finland
Temporomandibular joint disorders
3.1
8.6
34
109
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.7
8.6
152
909
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
8.5
750
6099
OIKOV, ,
NOMESCO Finland
16.3
8.5
13
8
S03.0
ICD-10 Finland
Dislocation of jaw
3.3
8.4
31
95
N06AB10
ATC
escitalopram; oral
1.3
8.4
604
4774
K07.05
ICD-10 Finland
Micrognatia (hypoplasia) of both jaws
90.1
8.4
9
*
K00.09
ICD-10 Finland
Lack of teeth due to lack of dental development UNS
3.3
8.2
30
92
OAB50
NOMESCO Finland
Delivery of care equipment and instruction on their use
3.0
8.1
35
118
WX199
NOMESCO Finland
Other local analgesia
2.3
8.1
61
272
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.3
8.1
800
6600
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
2.3
8.1
57
247
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
8.1
735
5999
KMAK, ,
NOMESCO Finland
1.3
8.1
1259
10973
POLI, ,
NOMESCO Finland
17.2
8.1
12
7
EGA05
NOMESCO Finland
Rinsing of mandibular joint
11.7
8.1
14
12
SBA00
NOMESCO Finland
Microbiological examinations
2.2
8.0
64
292
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
8.9
8.0
16
18
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
22.0
8.0
11
5
UDM02
NOMESCO Finland
Sinoscopy
2.3
8.0
55
236
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.3
7.9
529
4132
XKC03
NOMESCO Finland
Water cystometry
2.3
7.9
57
249
R03BA01
ATC
beclometasone; inhalant
1.5
7.9
274
1914
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
7.9
284
1999
OIKSI, ,
NOMESCO Finland
6.6
7.9
19
29
N06AA09
ATC
amitriptyline; systemic
1.6
7.8
160
993
G43.9
ICD-10 Finland
Migraine, unspecified
1.5
7.8
225
1513
OAB47, ,
SPAT
1.6
7.8
164
1025
SPAT1260
SPAT
Consultation of another employee
1.4
7.8
386
2879
RD211, ,
NOMESCO Finland
1.9
7.8
89
466
K03.30
ICD-10 Finland
Internal granuloma of pulp
4.0
7.8
21
52
A02BC02
ATC
pantoprazole; systemic
1.2
7.8
1503
13400
ECB10
NOMESCO Finland
Reconstruction of gingiva
9.4
7.8
15
16
A02BA02
ATC
ranitidine; systemic
1.4
7.7
297
2116
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
2.6
7.7
42
161
SPC50
NOMESCO Finland
Post and core abutment
15.0
7.7
12
8
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
2.5
7.7
48
197
SPAT1044
SPAT
Tympanometry
2.0
7.7
75
371
A78
ICPC
Infectious disease other/NOS
2.0
7.7
76
378
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
7.6
989
8426
WX723
NOMESCO Finland
CPAP therapy
1.8
7.5
100
550
A03FA02
ATC
cisapride; oral, rectal
1.7
7.5
124
728
SPE02
NOMESCO Finland
Metal-framed partial denture
2.8
7.5
35
124
RF211, ,
NOMESCO Finland
6.0
7.3
19
32
EG1DM
NOMESCO Finland
Mandibular joint very extensive MRI examination with 3 Tesla magnet
+∞
7.3
7
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
7.3
696
5706
SPAT1240
SPAT
Therapeutic discussion
1.4
7.2
343
2537
SPA05
NOMESCO Finland
Surgical guide
15.7
7.2
11
7
M03BX02
ATC
tizanidine; oral
1.2
7.2
1487
13304
N02BF02
ATC
pregabalin; oral
1.6
7.2
151
945
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.6
7.1
157
994
DHB50
NOMESCO Finland
Turbinoplasty
2.0
7.1
74
375
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.3
7.1
446
3450
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
7.1
177
1154
SPB06
NOMESCO Finland
Production of temporary clinic-made tooth- or implant-retained crown or bridge unit
3.3
7.1
25
75
A02BC01
ATC
omeprazole; systemic
1.3
7.0
525
4162
K12.2
ICD-10 Finland
Cellulitis and abscess of mouth
2.7
7.0
36
134
K05.11
ICD-10 Finland
Gingivitis (chronic) hyperplastic
4.1
7.0
19
47
SPC30
NOMESCO Finland
Surface-retained bridge
3.8
7.0
21
56
J01DB01
ATC
cefalexin; oral
1.3
7.0
2233
20932
TUPEI, ,
NOMESCO Finland
1.7
6.9
120
714
AA3AD
NOMESCO Finland
CT of face
3.4
6.9
24
71
XLD10
NOMESCO Finland
Gynaecological examination
2.8
6.9
34
124
K07.2
ICD-10 Finland
Anomalies of dental arch relationship
13.8
6.9
11
8
N03AX12
ATC
[U] gabapentin; oral
1.4
6.8
304
2224
Z16
ICPC
Relationship problem with child
4.1
6.8
18
44
EDC99
NOMESCO Finland
Other reconstructive operations on mandible
16.7
6.7
10
6
OIKKE, ,
NOMESCO Finland
4.3
6.7
17
40
M01AH01
ATC
celecoxib; oral
1.4
6.7
295
2155
SPAT1097
SPAT
Recording of ECG
1.5
6.7
219
1514
L43.8
ICD-10 Finland
Other lichen planus
2.7
6.7
33
121
SCB02
NOMESCO Finland
Instructions for self-performed oral hygiene
3.4
6.7
23
68
K11.71
ICD-10 Finland
Xerostomy (dry mouth)
3.3
6.7
24
73
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.0
6.6
69
350
M01AC06
ATC
meloxicam; systemic, rectal
1.3
6.6
680
5614
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.4
6.6
256
1829
ZXX04
NOMESCO Finland
Extent of procedure, 4 units
5.5
6.6
18
33
H02AB06
ATC
prednisolone; systemic
1.2
6.6
1027
8895
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.5
6.5
175
1160
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.5
6.5
211
1455
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
2.1
6.5
61
298
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.7
6.5
109
644
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
2.5
6.5
40
164
N06AB05
ATC
paroxetine; oral
1.6
6.5
138
868
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
6.5
409
3166
EFW99
NOMESCO Finland
Other operation on jaws
69.8
6.4
7
*
SPAT1193
SPAT
Pap smear
1.4
6.4
270
1958
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
6.4
839
7126
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.5
6.4
195
1331
R03AC02
ATC
salbutamol; inhalant
1.2
6.3
1469
13234
SPAT1051
SPAT
Guidance regarding sleep disorders
2.3
6.3
44
191
SPAT1359
SPAT
Use of symptom diary
2.1
6.3
53
249
XA420
NOMESCO Finland
Extensive sleep examination
3.1
6.3
25
81
HAHOM, ,
NOMESCO Finland
2.3
6.3
43
185
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
5.5
6.3
17
31
SPF50
NOMESCO Finland
Removal and reattachment of bridge
5.5
6.3
17
31
L07
ICPC
Jaw symptom/complaint
2.0
6.3
60
296
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
6.3
1014
8803
K01.12
ICD-10 Finland
Retained canine with obstruction in the upper jaw
3.2
6.3
24
76
SJC05
NOMESCO Finland
Bracket with demanding fixed attachment
+∞
6.2
6
*
POLMA, ,
NOMESCO Finland
+∞
6.2
6
*
C09CA06
ATC
candesartan; oral
1.3
6.2
473
3756
EEW99
NOMESCO Finland
Other operation on maxilla
26.6
6.2
8
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
6.2
120
737
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.5
6.2
169
1126
A30
ICPC
General and Unspecified, Medical examin/health eval complete
1.9
6.1
77
417
ECA00
NOMESCO Finland
Surgical exposure of tooth
2.7
6.1
31
115
N02AX02
ATC
tramadol; systemic, rectal
1.2
6.1
827
7039
J02AC02
ATC
itraconazole; systemic
1.4
6.1
347
2642
WX110
NOMESCO Finland
Infiltration anesthesia
1.2
6.1
2057
19202
EGC10
NOMESCO Finland
Arthroplasty of mandibular joint without graft
12.5
6.1
10
8
UKC02
NOMESCO Finland
Cystoscopy
1.5
6.1
198
1369
WX780
NOMESCO Finland
Remote monitoring CPAP
1.7
6.1
97
566
7143C
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[POLYARTHRITIS JUVENILIS SERONEGATIVA]
8.6
6.0
12
14
SDA05
NOMESCO Finland
Very demanding periodontal treatment
1.5
6.0
203
1412
K01.16
ICD-10 Finland
Retained molar with obstruction in the upper jaw
2.0
6.0
64
328
VALMI, ,
NOMESCO Finland
1.2
6.0
831
7088
KHV, ,
NOMESCO Finland
3.6
6.0
19
53

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1071
7440
1.69
37.81
3.6
2.8
0.01
0.04
estimate
0.58
357
2141
119
353
3.46
33.30
4.4
3.3
—
—
—
0
0
1312
9909
1.59
31.34
3.8
3.2
0.03
0.03
estimate
0.02
360
2183
1594
13081
1.48
22.92
4.1
3.4
0.01
5.95
estimate
2.77
415
2644
1594
13139
1.47
22.00
4.2
3.5
0.02
0.01
estimate
0.53
399
2534
348
2044
1.79
20.95
5.4
5.2
0.00
0.28
%
0.94
56
459
342
2008
1.79
20.60
5.0
5.0
0.20
0.11
%
0.55
62
496
351
2090
1.77
20.13
5.0
4.9
0.77
0.91
%
0.37
70
580
1562
12954
1.44
20.03
4.1
3.4
0.00
0.00
estimate
0.62
412
2640
337
2015
1.76
19.01
4.9
4.7
0.59
0.62
%
0.06
65
559
159
748
2.18
18.15
4.0
6.1
1.39
1.61
%
3.06
150
706
148
679
2.24
17.97
4.0
6.5
0.87
0.90
%
0.34
139
639
843
6409
1.44
16.47
5.4
4.6
—
—
—
0
0
559
3997
1.49
14.79
1.6
1.6
53144458.74
33314699.21
pmol/l
0.23
493
3497
946
7537
1.37
13.51
3.1
2.6
0.00
0.04
0.74
24
81
149
781
1.95
12.76
2.8
3.9
25.49
25.18
mmol/l
0.65
144
746
1257
10578
1.33
12.13
3.4
3.1
6.29
6.23
ph
1.45
794
6008
171
956
1.83
12.03
4.5
2.6
1.02
1.02
ratio
1.63
162
847
245
1529
1.65
11.68
3.3
3.7
1.23
1.23
mmol/l
0.58
218
1329
857
6858
1.35
11.50
4.0
3.5
0.00
0.00
estimate
0.19
390
2510
1302
11102
1.31
11.09
2.8
2.8
—
—
estimate
—
0
0
2212
20399
1.35
10.13
4.9
4.4
14.46
14.43
pmol/l
0.24
2074
19020
872
7132
1.31
9.74
2.6
2.7
81.50
58.46
u/l
0.43
820
6684
192
1197
1.64
9.21
4.5
4.3
136.73
131.94
g/l
2.62
186
1164
425
3147
1.41
8.98
2.4
3.0
3.85
4.71
e9/l
2.91
393
2839
1581
14070
1.27
8.73
3.6
3.3
77.27
85.23
ug/l
1.06
1520
13435
1411
12414
1.26
8.49
7.4
6.9
54.73
55.38
%
1.52
1371
11947
1235
10702
1.26
8.44
3.1
2.6
—
—
—
0
0
236
1583
1.53
8.30
3.0
2.5
0.24
0.36
e6/l
0.65
223
1498
1427
12630
1.25
7.94
7.6
7.0
31.08
30.23
%
2.67
1378
12073
174
1109
1.60
7.67
1.3
1.3
0.36
0.99
u/ml
—
7
84
101
559
1.83
7.45
4.0
7.3
1.23
1.22
mmol/l
0.00
90
489
996
8506
1.26
7.45
8.1
8.8
1.10
1.12
inr
1.10
865
7046
1324
11680
1.24
7.38
12.1
10.3
0.00
0.00
e9/l
0.43
1156
9523
1511
13589
1.23
6.80
7.7
7.0
1.95
2.01
e9/l
1.24
1419
12113
348
2618
1.37
6.63
1.6
1.6
1240.72
1167.97
nmol/l
0.90
283
2058
767
6426
1.26
6.62
3.0
2.5
—
—
—
0
0
1362
12159
1.22
6.45
7.8
7.2
0.70
0.68
%
0.50
1305
11478
1366
12200
1.22
6.44
7.8
7.2
8.54
8.46
%
0.54
1305
11541
752
6308
1.26
6.39
2.9
2.9
—
0.87
—
0
15
276
2018
1.40
6.24
2.8
2.3
13.17
11.69
nmol/l
2.07
256
1861
436
3423
1.32
6.23
2.6
2.6
2.53
2.46
g/l
2.28
402
3203
1358
12171
1.21
6.03
7.8
7.1
2.93
2.85
%
0.71
1300
11500
260
1895
1.40
5.99
3.0
3.5
4.72
4.65
pmol/l
0.48
240
1729
305
2283
1.37
5.99
1.4
1.4
145.74
266.82
u/ml
2.15
288
2128
1509
13671
1.21
5.97
8.0
7.3
0.18
0.19
e9/l
0.30
1405
12092
2343
22219
1.28
5.93
16.9
15.3
13.25
13.31
%
2.06
2309
21923
1464
13239
1.21
5.86
4.6
5.1
6.21
6.38
mmol/l
2.65
1354
12380
915
7916
1.22
5.73
1.4
1.5
1.39
1.66
u/ml
0.34
290
2124
24
81
2.97
5.65
1.2
1.3
69.46
67.21
ug/l
0.05
24
81
2434
23225
1.29
5.64
5.8
5.2
1.77
1.81
mu/l
1.05
2328
22126
1459
13242
1.20
5.45
7.8
7.0
0.53
0.54
e9/l
0.95
1350
11513
463
3732
1.28
5.40
2.7
2.6
15.38
14.46
umol/l
1.81
433
3509
1459
13258
1.20
5.33
7.8
7.0
0.04
0.04
e9/l
0.24
1348
11522
495
5958
0.79
5.16
4.9
4.4
94.90
93.92
%
0.47
485
5838
601
5023
1.24
5.14
1.4
1.3
20.62
25.02
iu/ml
0.69
172
1419
1191
10664
1.19
5.03
8.1
7.5
1.22
1.21
mmol/l
0.27
1048
9406
507
4177
1.26
4.91
3.5
2.9
559.46
543.46
mosm/kgh2o
0.67
454
3678
64
354
1.82
4.85
5.0
9.6
11.02
11.42
mmol/l
0.46
55
321
64
355
1.82
4.81
5.0
9.5
106.00
105.43
mmol/l
0.44
55
322
163
1139
1.45
4.78
2.7
3.0
74.11
127.93
ng/l
3.15
150
1011
525
4357
1.25
4.76
2.6
2.8
109.19
105.79
ug/g
0.10
430
3510
79
468
1.70
4.75
3.0
3.6
3.43
3.89
e9/l
1.39
79
468
1871
17475
1.19
4.75
7.6
7.6
77.11
78.89
u/l
0.99
1804
16693
135
917
1.49
4.58
1.0
1.1
8.52
4.91
eliau/ml
0.33
16
136
699
6004
1.21
4.54
3.5
3.3
1.02
2.07
kg/l
1.34
483
3847
547
4583
1.23
4.53
1.3
1.3
10.19
8.85
u/ml
0.20
259
1875
33
147
2.25
4.53
1.0
1.1
424.59
398.24
nmol/l
0.33
27
140
482
3983
1.25
4.53
1.5
1.4
492.43
507.34
titre
0.07
103
774
823
7183
1.20
4.51
2.8
3.0
25.01
56.17
ng/l
1.54
407
3806
724
6247
1.21
4.48
2.3
2.4
2.60
2.61
mg/l
0.05
662
5486
43
216
2.00
4.37
2.2
1.6
34.10
53.63
%
2.24
29
140
71
421
1.70
4.29
3.5
3.1
22.78
23.75
mg/l
0.08
55
282
1667
15483
1.17
4.28
3.4
3.2
—
4810.62
—
0
21
262
2024
1.32
4.21
4.0
3.5
—
—
—
0
0
169
2287
0.72
4.14
3.8
4.0
30.66
32.13
%
1.11
123
1670
2497
24093
1.25
3.99
13.6
13.3
3.92
3.92
mmol/l
0.52
2447
23564
130
903
1.46
3.99
1.5
1.9
0.23
0.23
g/l
0.13
123
861
1245
11344
1.17
3.96
2.9
2.6
76.77
73.13
nmol/l
4.71
1183
10661
131
913
1.45
3.95
2.4
2.2
—
—
—
0
0
639
5522
1.20
3.83
1.6
1.6
21.22
19.99
nmol/l
1.45
571
4898
200
1509
1.35
3.80
1.2
1.2
—
—
—
0
0
30
139
2.16
3.80
2.2
2.9
9.14
10.42
mg/l
0.73
25
121
2566
24864
1.27
3.76
13.3
12.5
18.69
21.08
mg/l
3.50
2099
19598
132
933
1.43
3.71
1.5
1.9
1.19
1.19
g/l
0.06
125
890
336
2728
1.26
3.69
2.3
2.3
362.50
376.23
nmol/l
0.63
321
2560
10
20
5.00
3.67
6.2
5.2
7.64
7.58
mmol/l
—
10
20
174
2297
0.74
3.66
2.4
2.5
33.50
58.57
u/l
0.62
152
1946
376
3101
1.24
3.59
2.7
2.7
25.39
23.70
%
1.44
349
2914
137
984
1.41
3.54
6.4
7.9
24.22
24.40
mmol/l
0.18
129
941
32
159
2.02
3.42
1.3
1.4
200.65
229.16
pmol/l
0.19
32
159
510
4363
1.20
3.39
2.8
3.2
528.59
690.98
ng/l
0.89
405
3574
1663
15593
1.15
3.35
4.7
4.0
1015.62
1301.10
e6/l
0.18
32
175
95
645
1.48
3.32
3.2
3.3
52.07
56.46
%
2.84
95
645
2482
24043
1.21
3.14
13.6
13.2
139.81
139.67
mmol/l
2.87
2436
23579
52
315
1.66
3.00
1.8
1.6
—
—
—
0
0
40
227
1.77
2.92
1.0
1.0
—
—
—
0
0
50
303
1.66
2.89
2.2
2.3
—
—
—
0
0
951
8647
1.14
2.88
3.8
3.4
30.42
30.36
u/l
0.01
914
8244
232
1860
1.26
2.87
1.2
1.2
121.67
175.95
titre
—
6
58
1552
14572
1.13
2.85
10.2
9.7
3.68
3.89
e9/l
4.41
1418
12650
1233
11423
1.13
2.78
5.8
6.3
10.26
10.67
umol/l
1.02
1178
10870
306
2542
1.22
2.76
1.2
1.2
82.58
149.63
u/ml
3.98
117
949
39
224
1.75
2.75
1.9
2.2
32.28
32.32
pg
0.02
39
224
25
129
1.94
2.48
3.8
2.1
1.06
2.09
u/field
1.28
17
86
1012
9318
1.13
2.44
5.4
5.3
37.36
37.12
g/l
0.80
961
8821
814
7394
1.14
2.44
3.1
3.2
2.35
2.36
mmol/l
0.61
769
6878
429
3725
1.17
2.40
3.2
3.4
227.74
516.87
ng/l
2.49
235
2261
136
1740
0.77
2.37
2.4
3.8
7.34
7.35
ph
0.13
106
1297
123
933
1.33
2.36
1.2
1.2
—
—
—
0
0
252
2088
1.22
2.36
7.9
5.1
4.64
4.77
kpa
0.57
246
2030
28
154
1.82
2.32
2.4
1.6
58.39
36.78
%
1.93
20
97
19
91
2.09
2.31
2.5
2.5
8.48
8.01
mmol/l
0.20
19
91
337
3903
0.84
2.31
3.6
2.8
0.92
1.09
e6/l
0.31
207
1948
39
237
1.65
2.29
1.8
1.7
140.57
749.35
pmol/l
—
7
33
93
680
1.38
2.27
1.3
1.2
22.60
41.35
u/ml
—
7
59
313
3641
0.84
2.26
3.8
3.0
2.98
3.50
e6/l
0.44
182
1693
79
564
1.41
2.23
1.1
1.1
—
—
—
0
0
216
1781
1.23
2.14
1.6
1.6
284.31
310.26
mu/l
0.69
198
1620
614
5521
1.14
2.13
2.1
2.0
0.99
0.98
mg/l
0.02
458
4136
355
3068
1.18
2.12
1.3
1.2
—
—
—
0
0
34
204
1.67
2.12
1.8
2.0
0.89
0.92
%
0.10
18
119
434
3812
1.16
2.11
4.9
4.4
1.66
1.84
ug/l
0.60
407
3505
90
674
1.34
1.94
2.7
2.7
6.41
5.69
umol/l
0.25
62
518
17
84
2.02
1.94
2.4
2.5
36.35
27.94
%
1.09
17
84
750
6880
1.12
1.86
1.5
1.5
2.01
2.10
g/l
1.13
534
4383
328
2851
1.17
1.84
1.6
1.6
—
—
—
0
0
664
6057
1.12
1.82
2.2
2.2
140.94
196.16
u/l
2.25
630
5797
5
12
4.16
1.82
4.6
3.0
4.40
4.19
mmol/l
—
5
12
146
1179
1.25
1.80
2.0
2.0
7.16
7.58
iu/ml
0.07
41
284
39
254
1.54
1.79
2.8
2.9
73.62
73.43
%
0.02
39
246
109
850
1.29
1.79
1.3
1.3
19.37
34.27
u/ml
—
9
45
2637
25886
1.19
1.78
15.5
14.5
69.38
69.98
umol/l
0.73
2617
25617
456
4071
1.14
1.77
1.7
1.6
—
—
—
0
0
536
4836
1.13
1.76
3.1
2.7
6.16
7.41
e6/l
1.29
493
4382
38
247
1.54
1.76
2.7
2.9
10.39
12.60
%
1.21
38
242
136
1666
0.80
1.72
2.1
2.0
—
—
—
0
0
0
48
0.00
1.69
0.0
1.2
—
7.38
—
0
37
26
156
1.67
1.67
1.1
1.2
—
—
—
0
0
271
2341
1.17
1.67
2.7
2.3
6364.72
6651.93
u/l
0.06
103
859
959
8960
1.10
1.65
1.9
1.9
97.70
97.83
pmol/l
0.03
500
4887
72
538
1.34
1.62
1.1
1.1
2.44
3.89
eliau/ml
0.74
45
250
136
1105
1.24
1.61
1.9
2.2
0.03
0.64
estimate
0.48
67
399
897
8365
1.10
1.60
1.7
1.6
—
—
—
0
0
182
2147
0.83
1.59
12.0
10.5
—
—
—
0
0
16
84
1.90
1.58
2.6
1.4
2.40
8.78
%
—
5
18
666
6123
1.11
1.58
4.2
4.0
7.39
7.40
ph
0.07
499
4284
274
2385
1.16
1.54
7.7
5.5
5.85
5.86
kpa
0.08
266
2318
196
1660
1.19
1.54
1.4
1.4
—
—
—
0
0
336
2970
1.14
1.53
1.6
1.5
—
—
—
0
0
13
64
2.03
1.53
1.2
1.1
—
—
—
0
0
13
64
2.03
1.53
1.2
1.1
—
—
—
0
0
13
64
2.03
1.53
1.2
1.1
—
—
—
0
0
1847
17819
1.09
1.52
3.5
3.4
37.96
38.11
u/l
0.02
1773
17140
28
177
1.58
1.50
1.9
1.5
7.15
6.19
mmol/l
0.56
22
136
125
1018
1.23
1.47
1.5
1.5
58.16
60.07
ug/l
0.20
125
1018
88
1110
0.78
1.47
9.7
12.3
24.05
24.23
mmol/l
0.20
83
1098
19
109
1.74
1.45
1.1
1.1
—
—
—
0
0
11
214
0.51
1.44
1.5
1.1
—
—
—
0
0
33
219
1.51
1.44
2.2
2.1
0.52
2.83
u/ml
2.57
13
67
293
2578
1.15
1.44
1.4
1.4
—
—
—
0
0
100
798
1.26
1.42
1.4
1.3
3.13
6.65
u/ml
—
9
75
709
7585
0.91
1.41
5.9
6.3
—
—
—
0
0
274
2404
1.15
1.41
7.7
5.5
7.39
7.37
ph
4.07
183
1507
27
174
1.55
1.35
1.1
1.1
—
—
—
0
0
290
2567
1.14
1.32
1.6
1.6
1149.29
991.32
mu/l
0.85
253
2200
68
523
1.30
1.31
2.4
2.3
129.08
133.28
g/l
0.92
62
434
12
219
0.54
1.30
1.3
1.4
1.46
1.41
nmol/l
0.07
12
202
571
6148
0.91
1.30
3.6
3.1
4.60
1.70
estimate
0.30
15
15
145
1217
1.20
1.30
1.5
1.3
—
—
—
0
0
99
800
1.24
1.29
1.4
1.3
6.53
13.09
u/ml
0.82
13
119
56
420
1.34
1.28
3.0
4.0
1.80
2.20
mmol/l
0.83
36
265
14
76
1.84
1.28
1.4
1.9
—
—
—
0
0
6
130
0.46
1.28
2.3
2.2
228.00
150.71
nmol/l
—
6
114
127
1058
1.21
1.24
7.5
12.8
16.73
16.21
%
1.63
119
1021
2266
22143
1.10
1.22
4.3
4.1
5.63
5.68
mmol/l
1.63
2148
20863
104
851
1.23
1.22
2.0
2.1
2.48
3.93
iu/l
3.65
45
376
8
37
2.16
1.21
2.0
1.7
—
—
—
0
0
2620
25802
1.14
1.20
11.5
10.5
26.40
26.12
u/l
0.30
2558
25244
150
1748
0.85
1.19
1.6
1.4
—
—
—
0
0
8
38
2.10
1.18
1.5
2.8
4.38
4.34
ug/l
—
8
38
38
272
1.40
1.17
1.4
1.3
0.32
3.96
u/ml
3.58
21
146
262
2327
1.13
1.16
7.8
5.5
1.58
1.71
mmol/l
0.30
228
1987
0
33
0.00
1.16
0.0
1.3
—
52.26
—
0
27
14
79
1.77
1.15
2.3
2.8
16.41
16.97
%
0.22
14
79
669
6246
1.09
1.15
1.8
1.8
—
—
—
0
0
90
733
1.23
1.12
1.1
1.1
—
—
—
0
0
17
103
1.65
1.11
1.6
2.4
—
—
—
0
0
246
2183
1.14
1.11
3.3
3.0
9.95
10.40
g/l
1.21
231
2050
90
734
1.23
1.11
1.1
1.1
—
—
—
0
0
15
88
1.70
1.10
1.4
1.6
0.00
0.03
estimate
0.49
15
88
219
1931
1.14
1.09
2.5
2.0
6.14
6.15
ph
0.03
135
1203
532
5698
0.92
1.09
2.6
2.4
—
—
—
0
0
24
349
0.68
1.07
2.2
3.1
3.01
50.52
u/ml
0.75
24
344
141
1206
1.17
1.06
1.8
1.7
—
—
—
0
0
9
45
2.00
1.04
2.2
1.0
—
—
—
0
0
28
195
1.44
1.03
1.1
1.1
—
—
—
0
0
2316
22704
1.09
1.02
16.4
15.4
333.70
333.23
g/l
1.87
2297
22556
41
306
1.34
1.02
3.0
3.4
1.35
1.38
%
0.02
36
284
0
30
0.00
0.97
0.0
1.3
—
3.60
—
0
25
262
2361
1.12
0.95
3.0
2.8
0.65
0.69
ug/l
0.37
130
1296
112
951
1.18
0.94
1.9
1.7
—
—
—
0
0
80
658
1.22
0.94
1.5
1.4
293.06
303.77
ug/g
0.17
41
354
15
93
1.61
0.92
3.3
1.8
100.32
98.02
ng/l
0.02
15
93
5
104
0.48
0.88
1.2
1.1
—
—
—
0
0
64
780
0.81
0.88
1.4
1.5
0.34
0.38
nmol/l
0.25
47
614
26
357
0.72
0.88
4.0
2.3
—
—
—
0
0
774
7345
1.07
0.87
3.3
3.6
8.43
8.27
mmol/l
0.35
696
6499
14
87
1.61
0.86
1.8
2.5
—
—
—
0
0
155
1362
1.14
0.86
2.5
2.7
25.44
48.81
u/ml
1.57
147
1321
49
387
1.27
0.85
1.6
2.0
4.45
5.33
mmol/24h
1.48
44
354
2785
27603
1.18
0.84
20.8
19.0
261.28
261.96
e9/l
0.25
2753
27099
542
5084
1.08
0.84
1.9
1.9
—
—
—
0
0
202
1808
1.12
0.84
1.2
1.2
—
—
—
0
0
24
331
0.72
0.84
1.2
1.2
—
—
—
0
0
2786
27615
1.18
0.83
20.7
18.8
30.06
30.01
pg
1.11
2771
27394
2786
27616
1.18
0.83
21.2
19.3
40.64
40.93
%
0.69
2770
27381
2786
27617
1.18
0.82
20.8
18.9
4.57
4.56
e12/l
0.14
2749
27057
21
294
0.71
0.81
1.0
1.3
0.14
0.22
nmol/l
0.73
11
227
14
89
1.57
0.80
1.1
1.2
—
—
—
0
0
235
2131
1.11
0.79
2.0
2.0
0.01
0.02
estimate
0.10
83
499
188
1684
1.12
0.79
7.5
10.9
124.42
123.13
g/l
0.44
180
1651
2785
27611
1.17
0.79
20.7
18.9
89.92
89.80
fl
0.80
2770
27389
157
1392
1.13
0.78
1.1
1.1
—
—
—
0
0
199
2193
0.90
0.77
2.8
3.0
0.23
0.22
g/l
0.37
189
2075
98
841
1.17
0.77
1.3
1.3
—
—
—
0
0
0
28
0.00
0.76
0.0
1.2
—
1.79
—
0
28
2786
27626
1.17
0.76
20.8
19.0
6.53
6.65
e9/l
2.25
2751
27047
822
7851
1.06
0.75
2.2
2.2
—
—
—
0
0
2786
27627
1.17
0.75
20.9
19.0
136.57
136.16
g/l
0.97
2771
27409
110
1255
0.87
0.74
12.0
5.2
—
—
—
0
0
208
1882
1.11
0.74
1.6
2.0
—
—
—
0
0
47
377
1.25
0.74
2.0
1.7
—
—
—
0
0
8
132
0.60
0.73
1.1
1.1
99.19
223.33
iu/ml
—
8
132
2201
21619
1.06
0.73
3.9
3.7
1.22
1.25
mmol/l
1.04
2109
20531
57
469
1.22
0.72
3.9
3.8
—
—
—
0
0
7
41
1.70
0.69
2.0
2.0
—
—
—
0
0
10
157
0.63
0.69
1.5
2.7
—
—
—
0
0
345
3209
1.08
0.69
2.9
2.8
28.53
29.46
s
3.39
330
3128
15
101
1.48
0.69
2.7
2.2
15.13
17.24
umol/l
0.31
15
101
40
318
1.26
0.69
1.5
1.4
0.37
0.38
g/l
0.11
29
233
40
318
1.26
0.69
1.5
1.4
2.70
2.92
g/l
0.44
29
234
35
274
1.28
0.68
1.1
1.1
210.33
233.04
mg/l
0.46
30
244
7
42
1.66
0.68
1.4
1.1
—
—
—
0
0
40
319
1.25
0.67
1.5
1.4
5.96
6.31
g/l
0.34
29
235
155
1389
1.12
0.67
1.5
1.7
8.42
8.65
u/l
0.09
120
1101
110
965
1.14
0.67
15.5
9.7
1.14
1.24
mg/l
1.58
103
921
13
190
0.68
0.66
1.1
1.1
—
—
—
0
0
187
1697
1.11
0.65
2.1
1.9
1.23
1.28
g/l
0.28
182
1597
83
715
1.16
0.65
2.2
1.6
119.45
138.81
au/ml
0.55
22
215
288
3087
0.92
0.65
9.5
7.3
1.10
1.10
mmol/l
0.13
267
2905
40
321
1.25
0.65
1.0
1.1
0.52
2.75
u/ml
1.66
14
141
78
901
0.86
0.65
1.5
1.3
—
—
—
0
0
115
1292
0.88
0.64
2.0
2.1
5.04
7.23
ug/l
1.71
107
1154
13
189
0.68
0.64
6.4
3.4
—
—
—
0
0
15
212
0.70
0.64
1.4
1.2
—
—
—
0
0
25
189
1.32
0.63
3.3
3.6
19.28
11.35
%
0.90
25
183
607
5779
1.06
0.63
4.1
4.3
6.12
8.61
mg/mmol
1.02
386
3727
115
1289
0.88
0.63
1.1
1.1
0.67
0.62
ratio
0.48
11
130
46
377
1.22
0.62
2.0
1.7
—
—
—
0
0
6
103
0.58
0.62
1.0
1.6
—
—
—
0
0
144
1590
0.90
0.61
4.4
4.3
7.42
16.26
ug/l
0.85
111
1204
46
378
1.22
0.61
2.0
1.7
—
—
—
0
0
46
378
1.22
0.61
2.0
1.7
—
—
—
0
0
12
175
0.68
0.61
1.3
1.3
—
—
—
0
0
97
1096
0.88
0.60
1.6
1.6
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
0.09
—
0
13
26
200
1.30
0.59
1.1
1.1
2044.54
1452.26
miu/ml
1.62
26
200
177
1613
1.10
0.59
3.8
3.5
66.18
71.37
e9/l
1.24
132
1136
51
426
1.20
0.58
3.6
3.5
21.11
24.72
nmol/l
1.47
51
416
68
583
1.17
0.58
1.5
1.4
25.65
21.75
u/l
0.39
51
495
299
2790
1.08
0.58
1.7
1.6
3.44
3.43
mmol/l
0.05
193
1849
6
35
1.71
0.57
1.2
1.1
0.46
0.02
u/ml
—
6
35
86
752
1.14
0.57
1.1
1.1
8.13
6.38
u/ml
0.28
51
371
39
318
1.23
0.57
1.5
1.4
—
—
—
0
0
162
1473
1.10
0.57
1.3
1.3
210.31
221.85
miu/ml
0.17
80
722
262
2800
0.93
0.57
3.7
3.4
7.51
6.72
umol/l
0.19
224
2427
20
149
1.34
0.56
1.6
1.3
71.15
73.02
umol/l
0.25
20
149
24
184
1.30
0.56
1.3
1.6
0.62
0.49
e9/l
1.73
24
184
174
1892
0.91
0.56
16.1
10.4
24.62
24.92
mmol/l
0.57
174
1887
189
1733
1.09
0.56
1.7
1.4
—
—
—
0
0
91
801
1.14
0.56
3.7
5.0
36.92
36.94
°c
0.25
91
794
16
115
1.39
0.55
1.0
1.1
0.37
9.78
u/ml
0.95
16
104
251
2332
1.08
0.55
1.6
2.0
—
—
—
0
0
147
1333
1.10
0.55
1.1
1.1
—
—
—
0
0
126
1134
1.11
0.54
1.2
1.2
1.26
3.02
u/ml
2.15
72
645
529
5043
1.06
0.54
3.8
4.1
—
—
—
0
0
67
579
1.16
0.53
1.6
2.6
0.67
0.83
nmol/l
1.56
58
498
35
285
1.23
0.53
1.1
1.2
36.68
39.60
mg/l
0.18
28
240
96
1072
0.89
0.52
1.5
1.5
—
—
—
0
0
9
132
0.68
0.51
1.3
1.1
—
—
—
0
0
85
751
1.13
0.50
2.1
1.6
—
—
—
0
0
22
170
1.29
0.50
1.1
1.2
—
—
—
0
0
251
2344
1.07
0.49
1.6
2.0
—
—
—
0
0
59
677
0.87
0.49
2.4
1.8
5.63
18.35
e6/l
1.52
48
496
18
234
0.77
0.49
1.7
1.5
—
—
—
0
0
109
981
1.11
0.48
1.1
1.1
1.92
2.60
u/ml
0.35
63
559
246
2299
1.07
0.48
1.5
1.6
23.67
22.64
iu/l
0.21
213
1912
216
2009
1.08
0.48
7.2
10.0
7.42
7.42
ph
0.24
130
1061
174
1872
0.92
0.47
8.2
9.4
1.23
1.27
mmol/l
0.30
168
1840
233
2176
1.07
0.47
1.6
2.0
—
—
—
0
0
117
1281
0.91
0.46
1.5
1.5
—
—
—
0
0
192
1781
1.08
0.46
7.4
10.6
96.30
96.13
%
0.11
177
1730
7
49
1.43
0.45
1.0
2.7
—
—
—
0
0
59
515
1.15
0.44
1.2
1.1
—
—
—
0
0
2334
23063
1.05
0.44
4.7
4.4
4.72
4.71
mmol/l
0.26
2244
22109
611
6305
0.96
0.43
3.7
3.2
0.24
0.32
e6/l
0.77
486
4506
17
130
1.31
0.43
2.6
2.0
—
—
—
0
0
178
1902
0.93
0.42
13.5
9.5
7.01
7.26
mmol/l
0.24
172
1846
183
1703
1.08
0.42
1.7
2.6
—
—
—
0
0
61
688
0.88
0.42
2.4
1.8
97.92
1135.01
e6/l
1.63
50
532
124
1344
0.92
0.41
1.1
1.1
1.56
1.54
g/l
0.34
124
1344
0
15
0.00
0.41
0.0
1.0
—
16.43
—
0
7
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
28
336
0.83
0.41
1.1
1.1
3.04
7.28
iu/ml
—
8
84
22
176
1.25
0.41
3.1
3.0
27.18
28.58
%
0.16
22
171
247
2327
1.06
0.40
1.6
2.0
—
—
—
0
0
96
1051
0.91
0.40
1.5
1.5
1.30
1.26
mm
0.33
71
761
234
2202
1.06
0.40
4.6
3.9
1.61
1.68
%
0.62
215
2024
299
2835
1.06
0.40
1.2
1.2
—
—
—
0
0
941
9157
1.04
0.40
2.0
2.0
—
—
—
0
0
33
388
0.85
0.39
4.8
6.2
399.29
385.61
umol/l
0.17
28
348
11
148
0.74
0.39
1.0
1.2
3.42
14.62
u/ml
1.21
11
100
334
3181
1.05
0.38
1.3
1.3
—
—
—
0
0
5
36
1.39
0.38
3.6
2.4
—
—
—
0
0
52
587
0.88
0.37
1.2
1.2
—
—
—
0
0
9
68
1.32
0.37
1.0
1.2
—
—
—
0
0
9
68
1.32
0.37
1.0
1.2
—
—
—
0
0
9
68
1.32
0.37
1.0
1.2
—
—
—
0
0
89
808
1.10
0.37
1.1
1.1
13.16
4.39
u/ml
0.88
59
435
213
2008
1.06
0.35
7.2
9.9
13.48
13.39
kpa
0.09
201
1942
213
2008
1.06
0.35
7.2
9.9
5.05
5.10
kpa
0.36
201
1940
61
544
1.12
0.35
1.9
1.6
347.71
371.69
mu/l
0.24
51
449
11
145
0.76
0.35
1.9
2.1
—
—
—
0
0
22
180
1.22
0.35
1.2
1.2
6.91
8.49
mm/h
0.79
22
180
244
2312
1.06
0.35
1.6
2.0
—
—
—
0
0
131
1402
0.93
0.34
1.5
1.5
70.06
60.53
ug/l
0.98
113
1191
161
1706
0.94
0.33
10.2
4.9
5.09
5.13
kpa
0.31
156
1648
18
145
1.24
0.33
1.2
1.2
1360.00
1035.71
titre
—
5
28
32
274
1.17
0.33
3.9
4.6
22.12
113.00
u/ml
—
9
86
6
88
0.68
0.33
1.0
1.1
—
16.00
%
—
0
7
6
89
0.67
0.33
2.7
2.1
—
—
—
0
0
16
127
1.26
0.33
2.1
2.6
498.00
584.07
ml
—
9
85
23
191
1.20
0.32
3.4
2.1
0.09
0.42
mmol/l
0.23
18
182
66
726
0.90
0.32
1.5
2.2
1.24
1.40
g/l
1.00
60
650
158
1674
0.94
0.32
10.3
4.9
7.42
7.41
ph
1.85
134
1416
170
1598
1.06
0.32
6.0
4.9
70.52
73.09
ng/l
0.23
152
1468
6
47
1.27
0.32
1.2
1.0
8.00
5.50
u/ml
—
6
47
64
704
0.90
0.31
1.0
1.1
0.05
0.41
u/ml
2.37
19
238
7
97
0.72
0.30
1.9
3.3
—
17.64
—
0
10
57
629
0.90
0.30
2.2
2.1
2.05
1.89
ug/l
0.05
50
570
93
1001
0.92
0.30
1.1
1.1
0.75
1.35
u/ml
0.79
43
497
587
5700
1.03
0.29
3.2
3.6
38.34
51.49
mg/l
0.92
360
3721
23
270
0.85
0.29
1.3
1.6
—
—
—
0
0
53
476
1.11
0.29
1.2
1.3
4.32
3.98
u/ml
0.10
19
217
14
173
0.81
0.29
3.6
5.1
10.46
9.32
mg/l
—
9
146
258
2683
0.95
0.29
1.7
1.5
—
—
—
0
0
18
216
0.83
0.29
2.8
2.5
4.69
1.40
g/24h
—
9
142
12
150
0.80
0.27
2.8
3.1
42.37
45.22
mg/l
—
7
109
9
118
0.76
0.27
1.2
1.5
72.78
315.31
nmol/24h
—
9
118
56
507
1.10
0.27
1.4
1.7
0.52
0.71
g/l
1.24
37
404
19
225
0.84
0.27
4.3
3.8
—
—
—
0
0
27
233
1.16
0.26
2.6
2.1
—
—
—
0
0
118
1106
1.07
0.26
3.8
3.3
20.49
20.83
s
0.41
101
981
208
1984
1.05
0.26
7.1
10.0
1.20
0.74
mmol/l
1.03
162
1642
26
298
0.87
0.26
2.5
4.0
11.34
1073.32
u/ml
0.70
20
277
315
3035
1.04
0.25
1.8
2.0
—
—
—
0
0
31
272
1.14
0.25
1.2
1.1
—
—
—
0
0
2315
22945
1.03
0.25
4.6
4.3
1.49
1.47
mmol/l
1.61
2222
21886
53
579
0.91
0.25
1.7
1.9
—
—
—
0
0
10
126
0.79
0.24
1.1
1.1
—
12.24
—
0
25
43
387
1.11
0.24
1.3
1.4
6.33
6.86
mmol/l
0.77
31
353
29
327
0.88
0.23
1.7
2.1
64.96
69.42
mmol/l
0.22
23
281
81
865
0.93
0.23
1.3
1.2
—
—
—
0
0
57
524
1.09
0.22
1.1
1.1
8.77
1033.25
iu/ml
0.60
11
140
41
371
1.10
0.21
1.1
1.1
1.47
1.46
g/l
0.07
41
342
40
439
0.91
0.21
1.2
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
5
42
1.19
0.21
6.0
5.5
—
—
—
0
0
5
42
1.19
0.21
1.0
1.0
—
—
—
0
0
35
314
1.11
0.21
1.0
1.2
0.63
6.03
u/ml
2.08
13
117
44
480
0.91
0.21
1.9
1.7
6071.87
10656.66
e6/l
1.19
38
340
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
108
1020
1.06
0.21
1.9
2.6
—
—
—
0
0
10
123
0.81
0.20
1.2
1.3
0.01
1.11
u/ml
—
10
123
71
757
0.93
0.20
2.2
1.7
367.91
473.80
mg/l
3.72
66
728
0
14
0.00
0.20
0.0
1.5
—
10.17
—
0
6
0
14
0.00
0.20
0.0
1.1
—
7.87
—
0
8
0
14
0.00
0.20
0.0
1.1
—
1.48
—
0
8
0
14
0.00
0.20
0.0
1.1
—
0.05
—
0
7
6
49
1.22
0.20
1.2
1.8
850004.08
718924.38
nmol/l
—
6
37
6
50
1.20
0.19
1.0
1.3
67.67
68.70
ug/l
—
6
50
2144
21256
1.02
0.19
5.4
5.0
37.31
37.61
mmol/mol
0.53
2058
20330
35
383
0.91
0.18
2.0
2.6
145.61
107.35
ug/min
0.11
20
242
19
165
1.15
0.18
3.6
3.3
0.17
0.21
e9/l
0.36
13
97
30
331
0.90
0.18
1.1
1.1
21.14
16.80
u/ml
0.27
12
132
28
251
1.11
0.18
1.2
1.1
—
—
—
0
0
7
59
1.18
0.18
1.4
1.3
—
—
—
0
0
31
280
1.10
0.17
1.0
1.1
0.15
0.66
u/ml
2.11
11
95
2334
23172
1.02
0.17
5.0
4.7
2.81
2.81
mmol/l
0.02
2245
22119
32
291
1.10
0.16
1.5
1.5
7.28
7.91
mmol/l
0.52
32
286
17
193
0.88
0.16
2.1
1.6
—
—
—
0
0
186
1796
1.03
0.16
1.5
1.7
—
—
—
0
0
8
72
1.11
0.16
1.5
2.8
0.64
0.62
mmol/l
—
8
72
6
78
0.77
0.15
1.7
1.2
—
—
—
0
0
9
81
1.11
0.15
4.3
1.8
—
—
—
0
0
350
3559
0.98
0.14
6.6
4.7
0.83
0.82
mmol/l
0.64
334
3402
8
98
0.81
0.13
1.0
1.2
26.25
29.04
s
—
8
98
8
99
0.81
0.13
1.1
1.1
—
—
—
0
0
8
100
0.80
0.13
1.0
1.0
—
—
—
0
0
139
1431
0.97
0.13
1.5
1.7
0.28
0.28
mg/l
0.00
65
645
88
841
1.04
0.13
6.8
4.9
219.46
408.69
mg/l
1.81
50
442
32
344
0.93
0.13
1.1
1.4
—
0.39
nmol/l
—
0
10
13
113
1.15
0.12
1.2
4.3
75.92
78.79
mg/l
0.08
13
86
137
1325
1.03
0.12
3.8
2.7
66.72
67.27
g/l
0.39
130
1257
13
147
0.88
0.12
8.4
3.9
0.62
0.74
index
0.21
13
147
54
511
1.05
0.11
1.1
1.1
—
—
—
0
0
100
1033
0.96
0.11
1.1
1.1
6.08
7.07
u/ml
0.22
56
617
69
719
0.96
0.11
1.1
1.2
—
—
—
0
0
15
133
1.13
0.11
1.4
1.5
139.87
133.68
nmol/l
0.16
15
133
26
280
0.93
0.11
1.9
1.8
—
—
—
0
0
19
208
0.91
0.11
1.4
1.2
—
—
—
0
0
30
279
1.07
0.10
1.2
1.3
—
—
nmol/l
—
0
0
196
1912
1.02
0.10
2.5
2.4
19.93
20.26
au/ml
0.03
23
243
181
1765
1.02
0.10
1.3
1.3
58.37
39.09
au/ml
0.43
11
103
11
124
0.88
0.09
1.1
1.1
—
—
—
0
0
26
242
1.07
0.09
3.6
4.0
—
—
—
0
0
6
55
1.09
0.08
1.3
1.3
—
—
—
0
0
10
113
0.88
0.08
1.2
1.0
18.47
35.45
iu/ml
—
10
113
55
571
0.96
0.08
1.2
1.3
—
—
—
0
0
24
223
1.07
0.08
3.2
2.9
0.64
0.70
e9/l
0.28
24
217
5
63
0.79
0.08
1.0
1.7
—
15.96
—
0
18
5
64
0.78
0.08
1.0
1.6
11.74
9.75
mmol/l
—
5
64
30
282
1.06
0.08
1.0
1.0
—
—
—
0
0
7
66
1.06
0.08
1.0
1.2
—
—
—
0
0
7
67
1.04
0.08
1.3
1.1
—
—
—
0
0
63
650
0.97
0.07
7.5
8.4
—
—
—
0
0
87
892
0.97
0.07
2.2
1.5
205.69
230.02
u/ml
0.34
48
502
759
7514
1.01
0.07
2.5
2.4
—
—
—
0
0
9
85
1.06
0.07
1.2
1.0
—
—
—
0
0
28
294
0.95
0.06
1.4
1.3
—
—
—
0
0
22
207
1.06
0.05
1.4
1.2
—
—
—
0
0
58
595
0.97
0.05
3.5
3.1
2.10
2.04
index
0.03
32
342
24
227
1.05
0.05
1.1
1.2
133.00
113.78
pmol/l
0.99
24
227
26
272
0.95
0.05
1.4
1.4
1.10
1.24
promille
0.22
21
222
10
90
1.11
0.05
1.3
1.3
—
—
—
0
0
54
523
1.03
0.05
1.1
1.1
—
—
—
0
0
13
140
0.93
0.05
1.0
1.3
—
71.57
%
—
0
14
28
267
1.05
0.04
1.0
1.1
—
—
—
0
0
883
8769
1.01
0.04
4.4
3.9
45.32
73.07
e6/l
1.39
632
5822
14
130
1.07
0.04
1.8
3.3
—
—
—
0
0
948
9485
0.99
0.04
7.9
7.1
1.21
1.21
mmol/l
0.19
889
8910
12
129
0.93
0.04
1.3
1.4
—
—
—
0
0
11
101
1.09
0.03
1.1
1.1
—
13.40
—
0
5
16
169
0.94
0.03
1.0
1.0
—
—
—
0
0
43
440
0.97
0.03
2.9
3.4
43.85
35.98
mg/l
0.18
34
375
43
440
0.97
0.03
2.9
3.4
33.14
61.87
mg/l
1.02
34
375
15
158
0.95
0.03
1.9
2.6
39.37
44.22
%
—
10
78
18
171
1.05
0.02
1.9
1.4
10254.91
97013.11
e6/l
1.28
11
115
291
2885
1.01
0.02
1.3
1.2
—
—
—
0
0
107
1079
0.99
0.02
1.8
1.7
22.63
9.37
u/ml
0.76
33
294
371
3682
1.01
0.02
2.0
1.8
3.52
3.42
ratio
0.65
270
2705
74
727
1.02
0.02
1.2
1.1
36.47
17.05
au/ml
0.33
23
169
25
241
1.03
0.02
1.1
1.1
—
—
—
0
0
14
133
1.05
0.01
1.4
2.9
2.24
2.65
mmol/l
0.44
14
123
725
7216
1.00
0.01
3.9
3.3
44.24
60.96
e6/l
0.31
595
5369
33
336
0.98
0.01
2.1
2.4
—
—
—
0
0
537
5345
1.00
0.01
2.6
2.7
316.48
321.95
umol/l
0.70
501
4867
24
245
0.98
0.00
1.0
1.1
290.33
291.34
mg/l
0.02
24
229
23
235
0.98
0.00
1.3
1.2
0.63
0.66
ratio
0.10
11
138
16
154
1.04
0.00
1.1
1.2
—
6.71
—
0
14
11
109
1.01
0.00
5.6
4.4
—
—
—
0
0
15
148
1.01
0.00
1.7
2.6
37.13
36.47
mmol/l
0.03
15
142
11
111
0.99
0.00
1.4
1.2
—
—
—
0
0
16
165
0.97
0.00
1.3
1.2
—
55.89
—
0
15
47
464
1.01
0.00
2.3
2.3
—
—
—
0
0
981
9775
1.00
0.00
2.0
1.9
1.32
1.36
mmol/l
0.76
862
8624
11
112
0.98
0.00
1.5
2.4
2187.73
2051.69
ml
0.17
11
104
13
125
1.04
0.00
1.1
1.4
133.11
159.98
mmol/24h
1.04
13
125
372
3710
1.00
0.00
2.3
2.5
2.41
2.42
mmol/l
0.94
339
3324
64
637
1.00
0.00
2.3
1.8
—
—
—
0
0
64
637
1.00
0.00
3.4
3.6
790.08
2193.11
u/ml
0.39
53
547
57
568
1.00
0.00
1.2
1.2
—
—
—
0
0
17
169
1.00
0.00
1.0
1.1
1.98
10.22
u/ml
—
10
110
16
164
0.97
0.00
2.1
3.1
1004.81
891.65
u/ml
0.12
16
164
39
384
1.01
0.00
2.4
3.3
1.65
2.03
ratio
0.50
23
214
0
6
0.00
0.00
0.0
1.0
—
2633.33
—
0
6
0
5
0.00
0.00
0.0
1.4
—
406.60
—
0
5
0
6
0.00
0.00
0.0
1.0
—
61.52
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
6.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
69
1.01
-0.00
1.1
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
177.11
—
0
9
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.6
—
0.54
—
0
7
0
9
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
1246.25
—
0
8
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
4.62
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
0.03
—
0
8
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
51
0.98
-0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint K11_MN_RETRGN and mortality.

Females

Parameter HR [95% CI] p-value
K11_MN_RETRGN 0.672 [0.55, 0.82] < 0.001
Birth year 0.993 [0.98, 1.0] 0.098

During the follow-up period (1.1.1998 — 31.12.2019), 137 out of 24333 females with K11_MN_RETRGN died.

Males

Parameter HR [95% CI] p-value
K11_MN_RETRGN 0.617 [0.5, 0.76] < 0.001
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 140 out of 22122 males with K11_MN_RETRGN died.

Mortality risk

Mortality risk for people of age

years, who have K11_MN_RETRGN.

N-year risk Females Males
1 0.071% 0.101%
5 0.414% 0.666%
10 0.931% 1.732%
15 1.766% 3.259%
20 3.271% 5.687%

Relationships between endpoints

↥

Index endpoint: K11_MN_RETRGN – Mandibular retrognathia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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