No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
179 |
4. Check minimum number of eventsNone |
179 |
5. Include endpointsNone |
179 |
6. Filter based on genotype QC (FinnGen only) |
161 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Congenital cataract
based on the number of shared cases.
Similar with more cases:
- Congenital lens malformations
- Congenital malformations of eye, ear, face and neck
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 161 | 100 | 61 |
| Unadjusted period prevalence (%) | 0.03 | 0.04 | 0.03 |
| Median age at first event (years) | 34.72 | 34.46 | 35.15 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 169
- Matched controls
- 1690
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q12.0
ICD-10 Finland
Congenital cataract
+∞
244.5
169
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
15.5
63.8
69
72
H27.0
ICD-10 Finland
Aphakia
379.3
32.0
31
*
H26.4
ICD-10 Finland
After-cataract
10.6
30.9
38
45
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
5.5
27.3
84
256
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
5.4
24.0
66
180
CJB10
NOMESCO Finland
Laser discission of secondary cataract
9.9
23.9
30
36
S01ED51
ATC
timolol, combinations; ophthalmic
8.5
20.6
29
40
114
Kela drug reimbursment
Glaucoma
8.6
20.2
28
38
7433A
ICD-9 Finland
Congenital anomalies of eye, Congenital cataract and lens anomalies
+∞
19.1
18
*
CKD60
NOMESCO Finland
Anterior vitrectomy
112.7
19.0
20
*
H26.00
ICD-10 Finland
Infantile, juvenile and presenile cataract
+∞
15.9
15
*
74439
ICD-8 Finland
Congenital anomalies of eye, Cataracta NUD
175.6
15.8
16
*
XCK10
NOMESCO Finland
Photography of fundus of eye
5.8
14.4
29
58
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
46.9
14.4
17
*
ZXA00
NOMESCO Finland
Right side
3.8
14.3
59
209
S01ED01
ATC
timolol; ophthalmic
18.2
13.9
21
13
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
43.9
13.4
16
*
WX140
NOMESCO Finland
Parabulbar anesthesy
12.0
13.3
24
23
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
140.0
12.6
13
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.8
12.4
31
75
TCG10
NOMESCO Finland
Removal of sutures from cornea
+∞
11.6
11
*
CJD20
NOMESCO Finland
Extracapsular cataract extraction with implantation of artificial lens in posterior chamber
+∞
11.6
11
*
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
+∞
11.6
11
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
23.3
10.9
15
7
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
117.0
10.5
11
*
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
35.0
10.5
13
*
H26.02
ICD-10 Finland
Presenil cataract
20.4
10.5
15
8
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.3
10.3
49
187
H33.0
ICD-10 Finland
Retinal detachment with retinal break
11.7
10.1
18
17
S01EE01
ATC
latanoprost; ophthalmic
8.7
10.0
21
27
H26.01
ICD-10 Finland
Infantile, juvenile and presenile cataract
58.4
9.8
11
*
ZXA10
NOMESCO Finland
Bilateral
3.2
9.6
46
175
ZXD10
NOMESCO Finland
Scheduled procedure
2.8
9.3
75
380
Z3229
NOMESCO Finland
Other healthcare associate professional
3.9
8.8
29
86
S01EC03
ATC
dorzolamide; ophthalmic
+∞
8.4
8
*
S01EC01
ATC
acetazolamide; systemic
15.5
8.3
13
9
S01BA04
ATC
prednisolone; ophthalmic
18.3
8.2
12
7
S01EA03
ATC
apraclonidine; ophthalmic
35.2
8.2
10
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
19.5
7.7
11
6
H50.1
ICD-10 Finland
Divergent concomitant strabismus
26.4
7.7
10
*
ZXD20
NOMESCO Finland
Day surgery
3.3
7.6
33
117
ZXA05
NOMESCO Finland
Left side
2.8
7.3
44
188
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
7.0
53
254
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
23.6
6.7
9
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.0
6.5
32
122
S01AX11
ATC
[U] ofloxacin
7.5
6.4
14
20
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
18.9
6.3
9
5
S01EC04
ATC
brinzolamide; ophthalmic
6.7
6.3
15
24
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
+∞
6.3
6
*
H54.4
ICD-10 Finland
Blindness, monocular
+∞
6.3
6
*
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
+∞
6.3
6
*
ZXE00
NOMESCO Finland
One hour or less
2.2
6.1
77
459
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
79
558
1.78
3.33
6.8
4.9
36.02
36.81
g/l
0.48
72
539
41
236
1.97
3.28
2.5
2.8
2.45
2.45
mmol/l
0.08
36
209
66
446
1.79
3.21
4.5
3.1
2.37
2.37
mmol/l
0.01
61
404
84
646
1.60
2.33
12.6
8.0
1.22
1.22
mmol/l
0.63
76
560
28
160
1.90
2.27
2.8
1.7
—
—
—
0
0
23
124
1.99
2.20
1.2
1.3
167.56
150.36
u/ml
—
9
45
23
130
1.89
1.93
9.5
8.6
-0.07
0.99
mmol/l
0.53
17
109
25
152
1.76
1.68
3.0
1.8
—
—
—
0
0
8
31
2.66
1.68
1.0
1.4
—
—
—
0
0
5
14
3.65
1.62
1.0
1.4
—
—
—
0
0
103
871
1.47
1.62
11.4
11.3
4.39
3.94
e9/l
0.67
93
749
94
783
1.45
1.58
10.4
5.4
6.60
6.33
mmol/l
0.62
89
724
33
221
1.61
1.57
2.7
1.9
—
—
—
0
0
53
402
1.46
1.44
2.8
2.9
0.12
0.27
e6/l
1.57
37
287
18
104
1.82
1.43
3.8
8.0
23.81
24.21
mmol/l
0.31
18
104
0
40
0.00
1.34
0.0
1.3
—
—
—
0
0
145
1335
1.61
1.34
15.3
12.4
89.18
90.27
ml/min/173m2
0.21
128
1201
45
336
1.46
1.31
1.9
1.5
21.01
22.27
nmol/l
0.21
39
286
66
532
1.39
1.26
2.5
1.8
103.56
98.48
pmol/l
0.38
32
271
19
117
1.70
1.24
4.8
12.9
24.42
25.13
mmol/l
0.40
19
117
17
103
1.72
1.18
1.9
2.8
13904.26
7642.86
u/l
—
9
41
7
30
2.39
1.14
1.1
1.1
—
—
—
0
0
7
30
2.39
1.14
1.1
1.1
—
—
—
0
0
8
41
2.00
1.10
2.3
1.5
—
—
—
0
0
38
285
1.43
1.08
1.2
1.3
55.43
33.79
iu/ml
—
9
77
47
367
1.39
1.07
4.6
4.0
5.56
11.22
mg/mmol
0.74
32
229
137
1264
1.44
1.06
5.5
5.3
38.11
37.74
mmol/mol
0.19
129
1195
25
342
0.68
0.95
3.1
2.6
—
—
—
0
0
11
63
1.80
0.92
1.5
1.7
20.18
4.56
mg/l
—
5
44
37
469
0.73
0.91
1.8
1.9
—
—
—
0
0
159
1523
1.74
0.91
21.4
16.0
77.86
72.25
umol/l
0.89
159
1504
8
42
1.95
0.90
2.3
1.7
—
—
—
0
0
116
1057
1.31
0.86
5.0
4.5
10.59
9.33
mm/h
0.60
111
987
6
32
1.91
0.82
1.3
1.6
—
—
—
0
0
153
1458
1.52
0.82
19.4
13.5
25.58
20.92
mg/l
0.83
134
1152
6
33
1.85
0.80
2.7
1.6
—
—
—
0
0
0
26
0.00
0.79
0.0
1.8
—
—
—
0
0
7
39
1.83
0.73
1.0
1.2
—
—
—
0
0
80
706
1.25
0.72
6.5
7.0
19.75
11.14
umol/l
0.59
75
673
127
1183
1.30
0.72
4.9
4.2
14.61
14.65
pmol/l
0.06
120
1086
5
27
1.88
0.69
2.0
1.6
—
—
—
0
0
58
497
1.25
0.67
3.6
3.4
—
—
—
0
0
5
28
1.81
0.66
1.0
1.2
—
—
—
0
0
28
352
0.75
0.64
7.0
3.6
1.01
1.02
kg/l
0.87
22
211
25
317
0.75
0.61
3.1
2.4
—
—
—
0
0
11
72
1.56
0.60
2.2
1.8
—
—
—
0
0
17
123
1.42
0.60
3.8
7.0
—
—
—
0
0
7
113
0.60
0.60
5.3
3.0
0.22
0.17
e6/l
—
7
107
0
23
0.00
0.58
0.0
3.7
—
6.21
—
0
23
109
1010
1.22
0.58
3.3
3.7
42.06
41.95
u/l
0.01
99
970
9
59
1.55
0.56
3.3
1.7
—
—
—
0
0
6
38
1.60
0.55
1.7
2.7
—
—
—
0
0
9
61
1.50
0.55
1.1
1.1
0.91
0.85
g/l
—
9
61
9
61
1.50
0.55
1.1
1.1
1.49
1.54
g/l
—
9
61
30
244
1.28
0.53
2.7
2.7
0.75
0.65
e6/l
0.13
15
125
22
172
1.32
0.51
2.0
1.6
1260.17
1268.21
nmol/l
0.01
12
136
29
236
1.28
0.51
7.0
4.0
62.73
305.35
ng/l
0.92
23
157
38
321
1.24
0.49
4.2
3.7
792.14
1104.83
ng/l
0.47
30
270
56
498
1.19
0.44
3.7
3.4
26.96
31.46
u/l
1.08
51
476
0
15
0.00
0.41
0.0
1.1
—
41.41
—
0
10
0
15
0.00
0.41
0.0
1.1
—
543.20
—
0
10
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
5
35
1.44
0.39
1.0
1.1
—
—
—
0
0
38
331
1.19
0.37
2.5
2.4
—
—
—
0
0
6
41
1.48
0.36
1.0
1.2
—
—
—
0
0
74
798
0.87
0.36
5.2
3.7
0.00
0.02
estimate
0.50
22
170
73
786
0.87
0.34
5.1
3.6
0.00
0.00
estimate
-0.00
23
180
6
47
1.29
0.32
1.2
1.1
—
13.59
—
0
7
19
160
1.21
0.27
7.5
9.8
104.74
104.49
mmol/l
0.08
19
160
26
227
1.17
0.25
2.8
2.9
3.15
2.79
e6/l
0.06
11
110
75
795
0.90
0.25
5.1
3.6
0.00
0.00
estimate
-0.00
23
177
6
81
0.73
0.24
1.5
1.6
48.38
61.09
ug/l
—
6
69
48
441
1.12
0.24
5.3
3.8
0.00
0.00
estimate
-0.00
22
171
141
1375
1.15
0.24
6.2
5.1
1.94
1.84
mu/l
0.40
136
1288
5
38
1.33
0.23
1.2
1.4
—
—
—
0
0
15
178
0.83
0.23
2.1
2.1
—
—
—
0
0
5
40
1.26
0.22
1.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
50.36
—
0
11
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
812.80
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
5.4
—
116.00
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
94.80
—
0
10
18
208
0.85
0.21
2.4
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
9
114
0.78
0.20
2.3
2.4
—
25.52
—
0
10
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
43
464
0.90
0.19
1.8
1.5
0.70
1.86
u/ml
1.13
13
115
129
1257
1.11
0.19
4.1
3.9
1.37
1.23
mmol/l
1.21
119
1182
68
646
1.09
0.18
3.4
2.7
—
—
estimate
—
0
0
13
110
1.20
0.17
1.1
1.0
—
—
—
0
0
36
332
1.11
0.17
1.8
2.4
0.89
1.47
mg/l
0.75
23
268
5
70
0.71
0.17
1.8
2.3
—
—
—
0
0
8
68
1.19
0.17
2.0
4.4
86.38
98.29
%
—
8
68
29
267
1.10
0.14
1.2
1.3
10.86
6.19
u/ml
—
10
101
138
1358
1.09
0.12
5.4
5.0
2.81
2.73
mmol/l
0.51
132
1286
132
1341
0.93
0.11
5.0
4.4
1.44
1.46
mmol/l
0.25
124
1267
49
469
1.06
0.10
3.1
3.6
21.44
160.38
ng/l
0.51
32
294
6
57
1.05
0.08
2.2
1.9
—
—
—
0
0
7
64
1.10
0.08
1.1
1.4
—
—
—
0
0
163
1618
1.21
0.08
28.6
20.9
135.44
136.51
g/l
0.48
163
1602
163
1618
1.21
0.08
29.0
21.2
40.13
40.80
%
0.81
163
1601
163
1617
1.23
0.08
28.3
20.7
89.91
90.08
fl
0.18
163
1602
57
587
0.96
0.07
2.1
1.9
1.27
1.34
mmol/l
0.35
45
505
15
162
0.92
0.06
2.6
2.7
0.77
0.71
ug/l
—
9
99
13
120
1.09
0.05
2.4
3.1
—
—
—
0
0
134
1328
1.04
0.04
4.5
4.4
5.90
5.75
mmol/l
0.45
126
1240
130
1288
1.04
0.04
25.3
17.5
333.14
333.21
g/l
0.03
130
1283
12
129
0.92
0.03
1.1
1.5
—
—
—
0
0
25
260
0.95
0.03
1.6
1.5
—
—
—
0
0
22
211
1.05
0.03
5.6
4.0
15.41
21.97
%
—
9
90
46
453
1.02
0.01
4.3
2.9
0.00
0.01
estimate
0.50
21
150
115
1143
1.02
0.01
3.9
3.7
—
—
—
0
0
59
597
0.98
0.01
5.3
3.4
0.00
0.02
estimate
0.74
21
151
14
143
0.98
0.00
2.5
3.4
0.24
0.22
g/l
0.42
14
132
14
143
0.98
0.00
5.5
4.6
29.89
32.25
%
—
9
104
135
1347
1.01
0.00
4.9
4.5
4.67
4.61
mmol/l
0.31
128
1280
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
10.19
—
0
7
0
7
0.00
-0.00
0.0
3.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
10.63
—
0
8
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
9.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
6
62
0.97
-0.00
8.5
5.0
66.03
51.95
%
—
6
62
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.3
—
51.50
—
0
8
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
17.64
—
0
5
5
58
0.86
-0.00
1.4
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
7
70
1.00
-0.00
2.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
59
0.84
-0.00
1.6
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
49
1.02
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
7.7
—
1310.00
—
0
9
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
82
0.97
-0.00
2.6
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
8
89
0.89
-0.00
1.4
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_CONGENITAL_CATARACT – Congenital cataract
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).