No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
675 |
4. Check minimum number of eventsNone |
675 |
5. Include endpointsNone |
675 |
6. Filter based on genotype QC (FinnGen only) |
592 |
Control definitions (FinnGen only)
- Control exclude
- H7_LIDLACRIMALORBIT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H04
- Name in latin
- Inflammatio viarum lacrimalium chronica
Similar endpoints
↥List of similar endpoints to
Inflammation of lacrimal passages (chronic)
based on the number of shared cases.
Similar with more cases:
- Disorders of lacrimal system
- Disorders of eyelid, lacrimal system and orbit
- Diseases of the eye and adnexa
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7052 | 5227 | 1789 |
| Only index persons | 5097 | 3749 | 1348 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.15 | 0.05 |
| Only index persons | 0.11 | 0.14 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 63.41 | 65.52 | 57.34 |
| Only index persons | 59.43 | 62.29 | 51.49 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 592 | 412 | 180 |
| Unadjusted period prevalence (%) | 0.13 | 0.15 | 0.08 |
| Median age at first event (years) | 60.28 | 59.95 | 61.06 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 609
- Matched controls
- 6090
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
+∞
307.7
485
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
1112.6
307.7
323
6
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
+∞
218.2
196
*
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
2496.7
188.8
173
*
CCD50
NOMESCO Finland
Dacryocystorhinostomy with insertion of tube
+∞
116.5
108
*
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
213.3
105.1
106
6
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
1135.3
101.2
96
*
36804
ICD-8 Finland
Inflammation of lachrymal glands and ducts, Dacryocystitis chronica
+∞
83.3
78
*
UDM02
NOMESCO Finland
Sinoscopy
19.9
83.0
66
37
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
838.5
77.1
74
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
7.8
75.6
118
183
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
4.6
72.9
394
1745
H04.10
ICD-10 Finland
Dry eye syndrome
7.6
70.3
111
174
H04.0
ICD-10 Finland
Dacryoadenitis
723.9
67.3
65
*
3754A
ICD-9 Finland
Disorders of lachrymal system, Chronic inflammation of lachrymal passages
+∞
64.8
61
*
S01AX11
ATC
[U] ofloxacin
7.9
55.6
82
118
3317
FHL
Transcutaneous dacryocystorinostomy (Toti)
+∞
49.7
47
*
CCD40
NOMESCO Finland
Percutaneous dacryocystorhinostomy
+∞
44.3
42
*
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
5.1
34.7
79
173
3755A
ICD-9 Finland
Disorders of lachrymal system, Stenosis and insufficiency of lachrymal passages
+∞
32.6
31
*
H02.3
ICD-10 Finland
Blepharochalasis
37.8
31.0
39
11
H04.2
ICD-10 Finland
Epiphora
84.4
29.0
32
*
CCD30
NOMESCO Finland
Reconstruction of lacrimal canaliculus
305.9
29.0
29
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.6
28.9
350
2087
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
4.9
26.1
61
136
F03
ICPC
Eye discharge
4.4
25.0
68
171
S01AA01
ATC
chloramphenicol; ophthalmic
4.5
23.1
59
141
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
+∞
23.1
22
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
5.0
22.6
51
110
36802
ICD-8 Finland
Inflammation of lachrymal glands and ducts, Obstructio, stenosis viarum lacrimalium
+∞
21.0
20
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
9.0
20.8
26
30
F29
ICPC
Eye symptom/complaint other
3.1
18.4
84
298
ZXA05
NOMESCO Finland
Left side
2.2
18.2
200
1088
H01.0
ICD-10 Finland
Blepharitis
4.6
17.9
44
102
3329
FHL
Other measure in this category
+∞
16.7
16
*
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
+∞
16.7
16
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.7
16.5
55
160
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.4
16.0
60
188
H02.1
ICD-10 Finland
Ectropion of eyelid
61.7
15.8
18
*
CCC50
NOMESCO Finland
Dacryocystectomy
+∞
15.7
15
*
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
87.4
15.6
17
*
ZXA00
NOMESCO Finland
Right side
2.1
14.6
197
1146
S01AA13
ATC
fusidic acid; ophthalmic
5.2
14.0
29
58
H02.4
ICD-10 Finland
Ptosis of eyelid
20.6
13.9
20
10
F73
ICPC
Eye infection/inflammation other
6.1
13.6
24
41
S01GX01
ATC
cromoglicic acid; ophthalmic
2.3
13.6
124
617
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.8
13.4
72
279
J01DB01
ATC
cefalexin; oral
2.2
12.8
493
4030
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
12.6
127
656
H57.1
ICD-10 Finland
Ocular pain
4.3
11.2
29
70
H10
ICD-10 Finland
Conjunctivitis
3.1
11.0
48
165
J01FF01
ATC
clindamycin; systemic
1.9
11.0
171
1030
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
10.8
139
784
S01ED51
ATC
timolol, combinations; ophthalmic
2.4
10.6
78
351
R01AD08
ATC
fluticasone; nasal
1.9
10.5
162
970
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
+∞
10.4
10
*
3315
FHL
Tear bag removal
+∞
10.4
10
*
S01ED01
ATC
timolol; ophthalmic
3.2
10.4
42
138
S01GX08
ATC
ketotifen; ophthalmic
3.7
10.1
32
90
J31.0
ICD-10 Finland
Chronic rhinitis
2.7
9.8
55
217
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.3
9.4
75
350
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
4.8
9.4
21
45
J01DA01
ATC
[U] cefalexin
1.7
9.3
379
2982
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
5.1
9.1
19
38
ZXA10
NOMESCO Finland
Bilateral
1.9
9.0
132
775
S01GX02
ATC
levocabastine; ophthalmic
2.9
8.8
42
152
J34.2
ICD-10 Finland
Deviated nasal septum
3.1
8.6
35
116
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.4
8.4
30
91
CCC99
NOMESCO Finland
Other operation on lacrimal passages
+∞
8.3
8
*
CCA30
NOMESCO Finland
Incision of lacrimal sac
+∞
8.3
8
*
S01EA05
ATC
brimonidine; ophthalmic
3.3
8.3
31
97
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
8.3
229
1609
R01AD09
ATC
mometasone; nasal
1.7
8.2
242
1729
S18
ICPC
Laceration/cut
1.6
8.2
281
2086
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
8.2
219
1525
H00.1
ICD-10 Finland
Chalazion
4.9
8.2
18
38
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
17.5
8.1
12
7
S01AA12
ATC
tobramycin; ophthalmic
17.5
8.1
12
7
H00.03
ICD-10 Finland
Preseptal cellulite in the eyelid
33.8
8.1
10
*
H10.4
ICD-10 Finland
Chronic conjunctivitis
10.2
8.1
15
15
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.5
7.9
27
80
ZXC10
NOMESCO Finland
Use of laser
4.0
7.8
22
57
WX002
NOMESCO Finland
Sedation and analgesia
1.8
7.8
122
729
J01AA02
ATC
doxycycline; systemic
1.7
7.7
459
3893
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.4
7.6
27
82
114
Kela drug reimbursment
Glaucoma
2.0
7.6
84
446
ZXD20
NOMESCO Finland
Day surgery
2.0
7.6
83
439
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
81.0
7.4
8
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
13.6
7.4
12
9
S01AA03
ATC
neomycin; ophthalmic
11.0
7.3
13
12
R01AD58
ATC
fluticasone, combinations; nasal
1.8
7.1
114
683
S01EE04
ATC
travoprost; ophthalmic
3.8
7.1
21
56
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
7.0
148
961
Z97.4
ICD-10 Finland
Presence of external hearing-aid
2.5
6.9
45
192
R42
ICD-10 Finland
Dizziness and giddiness
1.7
6.9
166
1117
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.3
6.8
51
232
S01GA55
ATC
phenylephrine, combinations; ophthalmic
40.5
6.8
8
*
N05BA04
ATC
oxazepam; oral
1.6
6.6
169
1153
3312
FHL
Probing under general anesthesia
70.6
6.4
7
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.9
6.4
92
532
J01FA10
ATC
azithromycin; systemic
1.5
6.4
293
2286
S01EX03, ,
ATC
3.0
6.3
27
92
S01AA30
ATC
combinations of different antibiotics; ophthalmic
11.2
6.3
11
10
CCD99
NOMESCO Finland
Other reconstructive operation on lacrimal apparatus
+∞
6.3
6
*
3743B
ICD-9 Finland
Other disorders of eyelids, Ptosis of eyelid[BLEPHAROCHALASIS ET DERMATOCHALASIS]
+∞
6.3
6
*
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
27.0
6.2
8
*
DJD20
NOMESCO Finland
Plastic repair of septum of nose
3.5
6.2
21
62
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.3
6.0
44
198
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
353
2866
1.55
6.45
9.3
9.3
4.09
4.22
e9/l
0.46
299
2503
520
4734
1.67
4.82
20.6
17.5
25.31
25.33
mg/l
0.00
454
3947
176
1292
1.51
4.81
2.4
2.3
—
—
—
0
0
432
3778
1.49
4.75
5.0
4.5
15.02
15.03
pmol/l
0.03
393
3413
532
4892
1.69
4.49
25.4
21.8
139.58
139.58
mmol/l
0.00
521
4790
532
4898
1.68
4.40
25.5
21.9
3.98
3.99
mmol/l
0.15
517
4785
398
3451
1.44
4.37
6.5
5.4
11.25
3097.80
e6/l
—
8
59
546
5069
1.75
4.28
31.3
27.0
91.75
91.46
fl
0.73
540
5000
546
5071
1.74
4.25
31.8
27.5
39.45
39.39
%
0.09
540
4999
546
5071
1.74
4.25
31.3
27.0
4.37
4.38
e12/l
0.15
538
4949
546
5074
1.74
4.20
31.5
27.2
131.88
131.57
g/l
0.19
541
5004
417
3660
1.44
4.19
5.0
4.5
12.54
14.41
mm/h
2.36
389
3385
288
2370
1.41
4.17
2.5
2.5
80.26
80.07
nmol/l
0.04
261
2092
324
2725
1.40
4.11
4.9
4.4
0.00
3.03
estimate
0.50
52
619
539
4998
1.68
4.10
27.8
23.9
79.59
78.79
umol/l
0.20
533
4925
545
5070
1.71
4.07
31.5
27.1
243.02
248.78
e9/l
1.30
537
4960
532
4923
1.64
4.00
13.9
12.5
22.72
23.94
u/l
1.47
511
4754
490
4452
1.51
3.99
6.5
5.6
2.03
2.00
mu/l
0.14
450
4040
325
2755
1.39
3.83
5.1
4.4
0.08
0.01
estimate
0.38
49
582
435
3874
1.43
3.83
8.6
8.1
77.82
80.48
u/l
0.32
417
3641
319
2704
1.38
3.72
4.9
4.3
0.00
0.00
estimate
0.50
51
593
356
3108
1.35
3.25
5.2
5.0
6.69
6.79
mmol/l
0.40
342
2958
506
4681
1.48
3.25
6.4
6.1
2.54
2.62
mmol/l
1.20
466
4253
155
1187
1.41
3.25
2.4
3.0
2.45
2.47
mmol/l
1.84
138
1072
289
2449
1.34
3.21
4.7
4.8
34.97
34.95
g/l
0.03
269
2288
258
2163
1.33
3.03
4.8
4.1
39.03
79.59
ng/l
0.77
195
1674
494
4575
1.42
2.92
5.4
5.2
4.49
4.57
mmol/l
0.90
456
4160
100
720
1.47
2.92
2.1
1.9
—
—
—
0
0
129
975
1.41
2.90
2.1
1.9
—
—
—
0
0
95
678
1.48
2.90
2.1
1.9
—
—
—
0
0
27
136
2.03
2.90
1.3
1.2
—
—
—
0
0
154
1200
1.38
2.89
5.6
4.6
1.02
1.02
kg/l
0.22
101
824
209
1709
1.34
2.88
2.2
2.1
127.00
236.81
u/l
1.73
195
1627
93
662
1.48
2.87
1.6
1.4
—
—
—
0
0
91
646
1.48
2.85
10.1
7.5
—
—
—
0
0
234
1953
1.32
2.78
2.7
3.5
2.35
2.36
mmol/l
0.61
215
1746
485
4493
1.39
2.73
7.0
7.0
39.90
39.97
mmol/mol
0.07
451
4151
286
2462
1.30
2.69
2.3
2.2
95.11
95.81
pmol/l
0.09
143
1243
26
136
1.95
2.54
1.3
1.2
—
—
—
0
0
71
492
1.50
2.51
2.7
2.4
3.46
7.39
ug/l
3.66
60
428
275
2372
1.29
2.49
3.0
2.8
—
—
estimate
—
0
0
283
2454
1.29
2.44
2.7
2.6
—
—
—
0
0
294
2563
1.28
2.43
6.6
6.3
1.21
1.21
mmol/l
0.62
271
2346
6
12
5.04
2.40
1.0
1.0
—
—
—
0
0
493
4607
1.37
2.40
5.8
5.5
5.97
6.02
mmol/l
0.40
452
4136
139
1097
1.35
2.38
5.7
5.7
3.10
2.82
ug/l
0.12
125
962
189
1561
1.31
2.35
5.1
4.4
0.00
0.01
estimate
0.74
45
549
113
867
1.37
2.31
4.5
4.7
22.22
22.17
%
0.01
60
438
468
4355
1.32
2.22
4.6
4.4
1.28
1.26
mmol/l
0.22
424
3898
486
4551
1.34
2.18
5.4
5.2
1.50
1.50
mmol/l
0.07
445
4120
33
198
1.70
2.13
1.1
1.1
—
—
—
0
0
8
26
3.10
2.02
4.4
1.9
—
—
—
0
0
481
4516
1.31
1.98
19.3
17.8
74.87
74.36
ml/min/173m2
0.22
452
4221
220
1887
1.26
1.98
3.4
3.3
1299.83
1647.91
ng/l
0.95
201
1629
315
2818
1.24
1.94
6.8
6.4
11.74
11.64
umol/l
0.05
300
2673
101
786
1.34
1.89
5.7
6.2
104.05
103.96
mmol/l
0.08
101
786
25
144
1.77
1.88
1.2
1.2
14.86
20.77
u/ml
—
5
7
7
23
3.07
1.80
2.3
2.6
314.43
1296.00
u/ml
—
7
23
316
2843
1.23
1.80
6.9
7.1
1.21
1.21
mmol/l
0.26
279
2444
21
118
1.81
1.72
1.1
1.1
—
12.73
—
0
8
234
2058
1.22
1.61
4.8
4.4
11.36
0.04
estimate
0.49
44
489
129
1062
1.27
1.61
1.2
1.3
2.57
1.42
u/ml
0.43
31
269
181
1551
1.24
1.60
3.2
3.4
0.44
0.45
e6/l
0.04
132
1168
152
1279
1.25
1.58
2.7
2.7
337.38
344.14
umol/l
0.34
133
1109
81
629
1.33
1.56
3.1
3.1
0.80
0.84
ug/l
0.11
55
409
23
139
1.68
1.50
1.2
1.2
3.83
9.56
u/ml
—
8
26
45
620
0.70
1.47
2.9
4.3
7.94
27.63
ug/l
0.87
34
518
13
66
1.99
1.44
1.0
1.0
—
—
—
0
0
6
22
2.74
1.43
1.7
1.8
12.63
5.90
umol/l
—
6
17
41
288
1.45
1.43
1.0
1.2
166.60
143.46
u/ml
0.08
12
105
23
143
1.63
1.37
1.6
1.4
—
—
—
0
0
54
403
1.37
1.36
2.7
2.8
58.59
61.79
ml/min/173m2
0.28
22
176
83
662
1.29
1.34
5.3
5.1
33.98
33.08
%
0.33
57
406
56
422
1.36
1.33
1.5
1.6
—
—
—
0
0
48
353
1.39
1.32
1.7
1.8
—
—
—
0
0
83
666
1.29
1.28
5.8
7.5
0.89
1.08
mmol/l
0.14
72
542
10
191
0.52
1.28
1.2
2.0
0.00
0.01
g/l
—
10
173
113
942
1.25
1.28
3.3
3.0
0.95
1.25
e6/l
0.54
56
506
288
2630
1.18
1.25
24.3
16.4
1.38
1.29
inr
1.47
237
2193
256
2317
1.18
1.23
3.0
3.0
118.92
127.63
ug/l
0.41
239
2118
25
164
1.55
1.22
1.5
1.4
278.40
285.52
ug/g
0.06
15
96
10
187
0.53
1.21
1.2
2.0
0.00
0.00
g/l
—
10
164
28
192
1.48
1.13
3.3
2.9
—
—
—
0
0
62
488
1.30
1.12
2.5
2.4
40.08
32.45
u/l
0.67
51
400
22
144
1.55
1.10
3.6
3.6
1.16
1.41
index
0.15
13
73
18
112
1.63
1.10
1.2
1.5
—
—
—
0
0
12
67
1.81
1.05
1.2
1.4
—
—
—
0
0
29
204
1.44
1.05
1.3
1.3
—
—
—
0
0
18
115
1.58
1.00
1.9
1.7
3.86
63.17
iu/l
—
10
39
10
174
0.57
0.98
1.2
2.1
0.00
0.00
g/l
—
10
163
200
1803
1.16
0.97
3.4
3.6
26.97
48.39
e6/l
1.09
152
1407
17
109
1.58
0.94
1.4
1.2
—
—
—
0
0
167
1489
1.17
0.94
2.2
2.3
2.87
3.08
mg/l
0.61
143
1275
144
1271
1.17
0.91
2.5
2.9
5.69
6.71
e6/l
0.44
131
1173
17
110
1.56
0.91
1.6
1.5
—
—
—
0
0
6
30
2.01
0.87
1.0
3.6
56.00
167.90
nmol/l
—
6
30
28
204
1.39
0.87
1.4
1.9
11.14
8.04
iu/ml
—
7
50
62
508
1.25
0.85
5.8
6.7
1.55
1.44
mmol/l
0.12
62
496
28
205
1.38
0.85
2.0
1.7
—
—
—
0
0
6
32
1.88
0.82
1.0
1.2
—
—
—
0
0
40
312
1.30
0.81
1.9
2.1
3.36
3.42
ratio
0.10
32
262
0
24
0.00
0.79
0.0
2.7
—
4.72
—
0
24
0
24
0.00
0.79
0.0
2.7
—
9.90
—
0
24
6
33
1.83
0.79
1.0
1.2
—
—
—
0
0
5
96
0.52
0.78
1.6
1.2
0.54
0.83
nmol/l
—
5
79
16
107
1.51
0.77
1.3
1.1
—
5.03
—
0
10
6
34
1.77
0.76
1.0
1.2
—
—
—
0
0
6
34
1.77
0.76
1.0
1.2
—
—
—
0
0
121
1071
1.16
0.75
5.6
4.3
313.68
310.52
ng/l
0.01
100
903
12
75
1.61
0.75
3.4
2.1
27.60
28.43
mg/l
—
5
28
101
882
1.17
0.74
1.4
1.3
16.40
34.50
iu/ml
3.35
32
277
42
336
1.27
0.72
6.3
3.3
24.32
24.29
mmol/l
0.02
42
330
17
117
1.47
0.72
3.9
3.6
22.78
29.08
mg/l
0.35
11
81
399
3823
1.13
0.71
25.7
22.6
13.79
13.86
%
0.53
394
3773
7
41
1.72
0.70
1.4
1.8
—
—
—
0
0
7
43
1.64
0.67
1.0
1.2
—
—
—
0
0
7
43
1.64
0.67
1.1
1.0
1.48
1.88
nmol/l
—
7
36
47
386
1.24
0.66
1.7
1.4
—
—
—
0
0
174
1595
1.13
0.65
3.3
3.4
28.27
32.04
u/l
1.40
161
1503
10
62
1.62
0.65
1.7
1.3
89965.60
53942.92
e6/l
—
5
36
7
44
1.60
0.65
3.3
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
24
181
1.34
0.64
2.7
2.5
0.38
0.39
iu/ml
0.04
16
109
69
593
1.18
0.63
5.3
3.3
1.52
1.97
mmol/l
0.49
64
498
71
613
1.18
0.61
1.5
1.4
—
—
—
0
0
179
1650
1.12
0.61
2.9
2.5
56.85
109.62
u/l
0.55
165
1515
28
218
1.30
0.61
2.0
1.9
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
8
52
1.55
0.59
1.1
1.3
—
—
—
0
0
71
618
1.17
0.57
5.2
3.3
5.80
5.79
kpa
0.02
71
596
6
36
1.67
0.57
1.0
1.2
—
—
—
0
0
192
1788
1.11
0.55
3.1
3.4
6.57
6.88
mmol/l
0.44
157
1496
120
1090
1.13
0.53
1.7
1.8
1303.46
1197.17
nmol/l
0.62
93
798
6
39
1.54
0.53
1.3
1.1
—
—
—
0
0
6
40
1.50
0.51
1.2
1.4
—
—
—
0
0
6
40
1.50
0.51
1.2
1.4
—
—
—
0
0
7
45
1.56
0.49
1.3
1.6
—
366.25
—
0
8
122
1117
1.12
0.48
2.1
1.6
1.76
1.41
mg/l
0.39
95
887
17
129
1.33
0.46
1.2
1.2
—
—
—
0
0
26
210
1.25
0.45
1.2
1.2
—
—
—
0
0
16
121
1.33
0.44
1.2
1.2
—
—
—
0
0
14
104
1.35
0.43
1.4
1.7
—
—
—
0
0
55
482
1.16
0.43
3.0
3.3
97.95
85.39
ng/l
0.47
50
412
8
57
1.41
0.42
1.0
1.1
—
—
—
0
0
13
96
1.36
0.42
1.2
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
95
867
1.11
0.41
3.6
3.2
3.11
2.97
e6/l
0.04
38
429
5
34
1.47
0.40
1.6
1.2
—
—
—
0
0
5
34
1.47
0.40
1.6
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
8.89
—
0
18
7
103
0.68
0.40
1.4
1.2
28.43
15.69
e6/l
—
7
77
7
103
0.68
0.40
1.1
1.2
1.49
1.55
g/l
—
7
103
7
105
0.66
0.39
1.4
1.3
58691.86
196.04
e6/l
—
7
81
5
35
1.43
0.39
1.2
1.4
—
—
—
0
0
90
823
1.11
0.38
1.5
1.3
10.45
13.17
u/ml
0.12
34
296
9
71
1.27
0.36
1.7
2.1
10.22
10.37
mmol/l
—
9
71
15
118
1.28
0.33
2.9
1.6
—
—
—
0
0
189
1800
1.07
0.32
3.7
4.2
5.98
8.47
mg/mmol
0.41
112
1119
14
110
1.28
0.32
1.4
1.2
—
—
—
0
0
14
110
1.28
0.32
1.4
1.2
—
—
—
0
0
13
101
1.29
0.32
1.9
1.4
—
210.00
—
0
10
22
184
1.20
0.31
1.2
1.2
3.20
2.33
u/ml
—
5
12
18
218
0.82
0.30
1.1
3.5
28.13
66.96
mg/l
1.34
18
189
17
138
1.24
0.30
1.7
1.5
—
—
—
0
0
18
217
0.82
0.29
1.1
3.5
36.47
81.11
mg/l
0.93
18
187
57
517
1.11
0.29
2.2
2.1
0.22
0.20
g/l
0.48
50
479
8
106
0.75
0.29
1.1
1.2
0.96
0.89
g/l
—
8
106
201
1929
1.06
0.27
1.9
1.9
1.35
1.33
mmol/l
0.15
174
1590
63
577
1.10
0.27
4.0
2.7
9.99
9.21
umol/l
0.09
51
501
11
86
1.28
0.26
1.2
1.5
—
—
—
0
0
11
87
1.27
0.24
2.1
1.9
49.36
40.79
nmol/l
0.26
11
80
5
38
1.32
0.23
1.2
1.0
—
—
—
0
0
16
134
1.20
0.23
1.6
1.7
—
—
—
0
0
5
39
1.28
0.23
1.2
1.0
—
—
—
0
0
7
93
0.75
0.22
2.1
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
61
567
1.08
0.21
3.8
3.7
—
—
—
0
0
10
80
1.25
0.20
1.1
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
15
175
0.85
0.19
3.7
3.0
1.27
1.60
mmol/l
2.43
15
170
6
53
1.13
0.18
1.0
1.1
133.33
113.67
%
—
6
48
29
261
1.12
0.18
2.2
1.8
—
—
—
0
0
7
60
1.17
0.18
9.0
3.7
64.57
72.60
u/ml
—
7
60
16
138
1.16
0.17
1.4
1.3
—
—
—
0
0
140
1451
0.95
0.17
3.7
3.9
0.54
0.02
estimate
0.47
46
479
8
72
1.11
0.16
2.0
2.0
208.25
233.40
pmol/l
—
8
65
8
72
1.11
0.16
1.1
1.3
—
—
—
0
0
15
130
1.16
0.15
1.7
1.5
—
—
—
0
0
8
73
1.10
0.15
1.1
1.3
—
—
—
0
0
8
73
1.10
0.15
1.1
1.3
—
—
—
0
0
36
332
1.09
0.15
3.9
3.6
44.68
48.23
%
0.49
36
324
28
307
0.91
0.15
1.6
1.5
—
—
—
0
0
10
119
0.84
0.15
1.7
1.3
563.50
503.81
mg/l
—
10
112
9
81
1.11
0.15
1.1
1.1
—
—
—
0
0
95
912
1.05
0.14
1.8
2.6
2.24
2.28
g/l
0.38
87
829
25
228
1.10
0.13
2.0
1.9
3.29
3.46
mmol/l
0.31
17
180
32
296
1.09
0.13
3.7
3.2
25.10
24.99
mmol/l
0.07
32
283
44
466
0.94
0.12
2.7
3.9
1.21
1.23
mmol/l
0.84
38
400
54
514
1.06
0.11
2.1
2.8
66.50
66.74
g/l
0.09
47
464
11
96
1.15
0.10
1.1
1.5
—
—
—
0
0
30
320
0.93
0.10
3.6
3.8
1.63
2.24
mmol/l
0.51
21
242
77
746
1.04
0.08
4.9
4.9
1.09
1.04
mmol/l
1.01
72
672
13
144
0.90
0.08
1.7
1.4
—
—
—
0
0
13
144
0.90
0.08
3.9
3.1
7.64
7.71
mmol/l
0.04
13
139
5
61
0.82
0.08
1.0
1.0
—
1.04
—
0
9
7
66
1.06
0.08
2.1
1.4
—
—
—
0
0
9
88
1.02
0.07
1.2
1.7
225.22
316.67
mu/l
—
9
82
17
158
1.08
0.06
1.6
1.5
—
—
—
0
0
303
3009
1.01
0.04
4.3
3.2
44.97
49.73
u/l
0.48
276
2772
16
151
1.06
0.03
1.3
1.3
—
—
—
0
0
27
260
1.04
0.03
1.9
1.8
0.43
1.76
ug/l
2.19
22
221
175
1735
1.01
0.03
1.7
1.7
21.04
20.48
nmol/l
0.19
153
1427
98
968
1.01
0.02
1.9
2.6
12.36
11.83
umol/l
0.35
88
890
25
243
1.03
0.01
2.2
1.7
—
—
—
0
0
121
1217
0.99
0.01
1.8
1.8
416.70
11818632.10
pmol/l
0.80
98
990
11
116
0.95
0.00
1.2
1.4
—
—
—
0
0
16
154
1.04
0.00
2.8
1.5
—
—
—
0
0
84
844
0.99
0.00
1.8
2.6
21.16
20.69
%
0.12
76
776
89
894
0.99
0.00
3.7
3.1
0.87
0.82
mmol/l
2.85
84
837
12
121
0.99
0.00
1.9
1.8
—
—
—
0
0
25
249
1.00
0.00
1.2
1.8
1.70
1.53
g/l
0.22
19
221
7
71
0.99
0.00
1.1
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
9.86
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
1.27
—
0
9
0
5
0.00
-0.00
0.0
8.4
—
5.82
—
0
5
0
8
0.00
-0.00
0.0
7.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
5.96
—
0
5
6
63
0.95
-0.00
4.0
3.6
—
—
—
0
0
5
50
1.00
-0.00
2.6
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
12.55
—
0
6
6
69
0.87
-0.00
1.8
1.5
—
—
—
0
0
7
70
1.00
-0.00
1.1
1.3
—
—
—
0
0
6
66
0.91
-0.00
1.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
15.20
—
0
5
7
70
1.00
-0.00
1.1
1.3
—
—
—
0
0
5
52
0.96
-0.00
1.6
1.3
6.54
29.05
u/l
—
5
41
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.5
—
61.83
—
0
6
7
75
0.93
-0.00
1.6
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
9.3
—
10.10
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.2
61.20
100.94
pmol/l
—
5
50
Mortality – FinRegistry
↥Association
Association between endpoint H7_LACRIMINFLAMCHRON and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_LACRIMINFLAMCHRON | 0.99 [0.89, 1.11] | 0.858 |
| Birth year | 0.995 [0.99, 1.0] | 0.231 |
During the follow-up period (1.1.1998 — 31.12.2019), 939 out of 2779 females with H7_LACRIMINFLAMCHRON died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_LACRIMINFLAMCHRON | 0.993 [0.84, 1.18] | 0.931 |
| Birth year | 0.991 [0.98, 1.0] | 0.127 |
During the follow-up period (1.1.1998 — 31.12.2019), 290 out of 989 males with H7_LACRIMINFLAMCHRON died.
Mortality risk
Mortality risk for people of age
years, who have H7_LACRIMINFLAMCHRON.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.102% | 0.225% |
| 5 | 0.573% | 1.344% |
| 10 | 1.423% | 3.252% |
| 15 | 2.833% | 6.231% |
| 20 | 5.208% | 10.524% |
Relationships between endpoints
↥Index endpoint: H7_LACRIMINFLAMCHRON – Inflammation of lacrimal passages (chronic)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data