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Melanoma in situ of scalp and neck

DOID Endpoint Browser PheWeb

CD2_INSITU_MELANOMA_SCALPNECK

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D03.4&
  • Cause of death: ICD-10 — D03.4&

2 out of 7 registries used, show all original rules.

100

4. Check minimum number of events

None

100

5. Include endpoints

None

100

6. Filter based on genotype QC (FinnGen only)

94

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D03
Name in latin
Melanoma in situ verticis cranii

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 94 32 62
Unadjusted period prevalence (%) 0.02 0.01 0.03
Median age at first event (years) 71.32 70.38 71.80

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
94
Matched controls
940
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D03.4
ICD-10 Finland
Melanoma in situ of scalp and neck
+∞
135.4
94
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
48.9
82.9
72
59
L57.0
ICD-10 Finland
Actinic keratosis
8.3
22.8
42
83
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
9.8
19.8
27
37
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
+∞
19.4
18
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.4
18.1
34
67
R23.8
ICD-10 Finland
Other and unspecified skin changes
6.2
17.5
48
136
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
8.0
16.7
27
45
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
102.6
16.1
17
*
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
10.7
10.4
20
23
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
45.2
10.2
12
*
C43.42
ICD-10 Finland
Malignant melanoma of the scalp and neck: 'superficial spreading' type
+∞
9.5
9
*
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
41.0
9.2
11
*
S18
ICPC
Laceration/cut
4.3
9.1
71
393
ZZR00
NOMESCO Finland
Flap of skin
18.6
8.8
13
8
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
13.5
8.4
14
12
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
20.5
7.8
11
6
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
8.0
7.7
17
25
C43.41
ICD-10 Finland
Malignant melanoma of the scalp and neck originating in lentigo maligna
+∞
7.4
7
*
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
12.3
6.5
11
10
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
8.2
6.2
13
18

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
55
111
10.53
30.45
2.1
1.3
—
—
—
0
0
76
336
7.59
16.37
4.3
2.2
—
—
—
0
0
23
82
3.39
5.46
1.6
1.3
—
—
—
0
0
61
422
2.27
3.49
7.1
5.7
35.45
34.59
g/l
0.73
55
395
13
38
3.80
3.48
1.3
1.2
—
—
—
0
0
48
302
2.20
3.47
12.0
5.7
—
—
—
0
0
63
447
2.24
3.32
10.0
6.1
0.17
0.19
e9/l
0.45
52
394
53
358
2.10
3.09
5.0
4.1
251.18
117.14
e6/l
0.43
36
264
61
437
2.13
3.01
9.8
5.8
0.63
0.62
e9/l
0.09
49
373
61
439
2.11
2.95
9.8
5.8
0.04
0.04
e9/l
0.19
49
374
29
158
2.21
2.91
3.6
3.3
1.18
1.95
e6/l
0.41
17
84
23
115
2.32
2.81
1.7
1.3
537.14
433.10
titre
—
7
29
61
446
2.05
2.74
9.9
5.8
1.81
1.71
e9/l
0.38
50
400
41
266
1.96
2.54
3.7
3.1
—
—
estimate
—
0
0
12
46
2.84
2.47
1.1
1.5
—
—
—
0
0
65
498
1.99
2.42
12.9
10.0
4.19
4.28
e9/l
0.13
51
435
6
13
4.85
2.31
1.7
1.1
—
—
—
0
0
47
328
1.87
2.28
4.1
3.4
94.16
239.04
e6/l
0.33
34
255
89
796
3.22
2.26
23.1
20.1
22.88
26.87
mg/l
0.75
80
675
42
286
1.85
2.18
3.8
3.1
0.14
0.62
e6/l
1.41
30
215
80
676
2.23
2.07
11.0
9.3
81.47
83.67
u/l
0.20
75
639
44
313
1.76
1.92
4.8
3.6
2.37
2.35
mmol/l
1.01
39
282
7
22
3.35
1.92
1.0
1.0
—
—
—
0
0
8
29
2.92
1.84
1.1
1.1
—
—
—
0
0
61
482
1.76
1.80
10.0
8.4
1.21
1.20
mmol/l
0.10
54
414
45
328
1.71
1.77
2.2
2.1
1.60
1.30
mmol/l
0.79
33
257
14
69
2.21
1.75
1.9
1.6
—
—
—
0
0
16
84
2.09
1.72
3.9
2.4
—
—
—
0
0
38
266
1.72
1.72
4.4
3.5
0.71
0.81
ug/l
0.45
25
188
72
601
1.85
1.72
3.7
4.1
15.06
15.08
pmol/l
0.02
60
515
59
469
1.69
1.64
4.2
4.4
0.00
0.00
estimate
-0.00
11
89
58
459
1.69
1.64
3.8
4.3
0.00
0.00
estimate
—
10
102
87
785
2.45
1.61
6.4
5.8
4.39
4.34
mmol/l
0.17
78
710
6
20
3.13
1.61
12.2
6.1
—
—
—
0
0
8
33
2.55
1.58
1.6
2.0
23.13
20.39
s
—
8
33
58
463
1.66
1.55
4.2
4.4
0.00
15.47
estimate
0.50
11
105
44
333
1.60
1.42
5.4
3.6
7.35
8.03
mmol/l
0.60
37
264
86
784
2.14
1.41
6.7
5.7
1.42
1.43
mmol/l
0.08
75
700
49
381
1.60
1.41
13.6
13.7
0.00
0.01
e9/l
0.52
35
320
14
77
1.96
1.34
3.4
2.2
10.00
10.91
g/l
0.27
14
67
84
759
2.00
1.25
5.4
4.8
1.34
1.26
mmol/l
0.44
73
675
85
776
1.99
1.23
9.0
7.8
40.17
40.91
mmol/mol
0.28
75
720
24
161
1.66
1.23
1.9
1.5
2.42
3.26
g/l
0.96
17
92
11
57
2.05
1.23
1.9
3.1
23.98
23.57
mmol/l
0.12
11
57
8
38
2.21
1.22
1.0
1.2
—
—
—
0
0
19
121
1.71
1.17
4.4
2.8
79.18
73.19
e9/l
0.19
13
93
20
130
1.68
1.14
1.9
1.4
—
—
—
0
0
14
82
1.83
1.12
1.3
1.5
—
—
—
0
0
8
41
2.04
1.12
1.5
1.2
—
32.70
—
0
5
5
21
2.46
1.10
2.4
1.4
60.20
61.35
%
—
5
21
41
320
1.50
1.09
1.8
1.7
17.52
21.28
nmol/l
1.02
34
249
82
744
1.80
1.08
5.7
5.1
2.12
2.05
mu/l
0.07
71
651
44
351
1.48
1.04
3.7
4.2
6.41
6.26
ph
0.34
16
194
86
798
1.91
1.04
20.3
19.2
—
—
—
0
0
0
30
0.00
0.99
0.0
5.5
—
—
—
0
0
43
345
1.45
0.97
6.3
4.4
8.82
9.54
mg/mmol
0.08
32
226
13
78
1.77
0.97
1.3
1.6
—
—
—
0
0
17
111
1.65
0.96
2.6
4.1
7.36
7.38
ph
—
10
68
16
103
1.67
0.95
6.2
6.9
8.64
10.89
mmol/l
0.75
16
97
15
95
1.69
0.94
1.1
1.5
—
—
—
0
0
33
413
0.69
0.91
4.8
4.7
47.44
55.80
ng/l
0.18
25
334
8
45
1.85
0.87
2.5
2.8
—
—
—
0
0
20
140
1.54
0.86
1.7
1.3
—
—
—
0
0
41
333
1.41
0.84
5.9
3.6
37.63
60.15
mg/l
0.73
35
231
39
314
1.41
0.84
3.1
2.7
—
—
—
0
0
6
32
1.93
0.83
1.7
1.2
—
—
—
0
0
29
222
1.44
0.82
3.3
3.5
—
0.40
—
0
5
37
297
1.41
0.81
5.2
4.4
7.39
7.40
ph
0.33
27
218
0
24
0.00
0.80
0.0
1.9
—
1.71
—
0
24
15
100
1.59
0.79
8.1
9.4
1.12
1.35
mmol/l
0.53
15
100
7
41
1.76
0.71
1.1
2.2
—
0.00
estimate
—
0
7
5
27
1.90
0.69
5.2
1.3
—
—
—
0
0
11
70
1.65
0.68
4.8
3.4
0.50
0.48
%
—
6
24
34
280
1.34
0.61
4.4
4.3
0.00
0.00
estimate
—
10
91
0
20
0.00
0.61
0.0
1.5
—
—
—
0
0
0
22
0.00
0.60
0.0
3.3
—
—
—
0
0
55
487
1.31
0.59
20.5
18.6
1.34
1.33
inr
0.05
47
418
16
117
1.44
0.57
4.8
4.9
3.81
46.80
ug/l
0.60
16
93
9
60
1.55
0.56
1.2
1.2
—
—
—
0
0
6
38
1.62
0.55
1.3
2.6
—
—
—
0
0
14
102
1.44
0.51
1.9
1.4
—
—
—
0
0
47
414
1.27
0.50
3.4
3.1
—
—
estimate
—
0
0
33
282
1.26
0.44
8.2
6.7
—
—
—
0
0
52
469
1.24
0.43
7.0
6.3
2.19
2.85
ug/l
0.40
44
404
0
16
0.00
0.41
0.0
2.0
—
90.35
—
0
16
19
152
1.31
0.41
1.2
1.8
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
2.5
—
9.82
—
0
17
49
442
1.23
0.40
3.1
2.2
86.83
95.74
pmol/l
0.76
30
223
30
258
1.24
0.37
3.5
3.8
0.11
0.00
estimate
—
9
80
10
73
1.41
0.36
5.5
3.6
0.00
0.38
%
—
5
21
10
73
1.41
0.36
1.4
2.1
—
0.00
estimate
—
0
12
11
82
1.39
0.36
3.5
3.8
—
—
—
0
0
6
45
1.36
0.34
4.2
3.4
4.45
4.38
pmol/l
—
6
37
12
92
1.35
0.34
10.1
10.8
—
—
—
0
0
20
170
1.22
0.27
2.8
1.9
31.50
29.38
s
0.59
20
163
25
221
1.18
0.23
1.4
1.3
—
—
—
0
0
5
40
1.26
0.23
1.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
3.2
—
2.99
—
0
10
0
12
0.00
0.21
0.0
2.8
—
73.25
—
0
12
33
301
1.15
0.21
5.9
5.0
—
—
—
0
0
0
13
0.00
0.21
0.0
4.4
—
105.54
—
0
13
0
13
0.00
0.21
0.0
4.4
—
1.20
—
0
13
0
13
0.00
0.21
0.0
4.4
—
4.16
—
0
13
25
224
1.16
0.20
1.4
1.8
445.68
466.97
pmol/l
0.15
19
185
10
81
1.26
0.19
3.0
3.6
—
—
—
0
0
38
353
1.13
0.18
4.4
4.5
0.33
0.00
estimate
—
9
86
22
197
1.15
0.17
2.0
2.3
13.81
12.83
umol/l
0.27
22
181
20
179
1.15
0.16
6.0
4.8
—
—
—
0
0
12
105
1.16
0.11
1.3
1.8
—
—
—
0
0
20
184
1.11
0.10
1.9
2.3
2.28
2.21
g/l
0.26
20
167
6
58
1.04
0.08
10.0
3.1
—
—
—
0
0
29
275
1.08
0.08
4.1
3.4
—
—
—
0
0
6
71
0.83
0.08
2.0
1.5
—
—
—
0
0
16
147
1.11
0.08
7.9
8.5
7.44
7.42
ph
—
8
87
8
73
1.10
0.08
11.4
7.5
25.50
24.80
mmol/l
—
8
73
7
81
0.85
0.07
2.4
4.6
—
—
—
0
0
25
256
0.97
0.00
4.2
3.8
—
—
—
0
0
20
198
1.01
0.00
1.6
1.7
755.19
1282.17
nmol/l
3.10
15
154
18
177
1.02
0.00
1.8
2.3
23.99
22.32
%
0.23
18
163
16
165
0.96
0.00
11.2
8.1
104.81
103.83
mmol/l
0.23
16
165
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
30.67
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
1.20
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
1.72
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
15.73
—
0
7
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
9
98
0.91
-0.00
2.4
2.7
0.26
0.21
g/l
—
9
89
5
49
1.02
-0.00
1.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
9.03
—
0
9
5
57
0.87
-0.00
2.2
3.4
1.34
1.37
%
—
5
57
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
55
0.90
-0.00
2.2
3.3
0.66
0.68
%
—
5
55

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_MELANOMA_SCALPNECK – Melanoma in situ of scalp and neck

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).