ankylosing spondylitis: An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditions
|
4038 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
1907 |
4. Check minimum number of eventsNone |
1907 |
5. Include endpointsNone |
1907 |
6. Filter based on genotype QC (FinnGen only) |
1746 |
Control definitions (FinnGen only)
- Control conditions
- not M13_ANKYLOSPON_ICD10
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF3
Similar endpoints
↥List of similar endpoints to
Ankylosing spondylitis, strict definition
based on the number of shared cases.
Similar with more cases:
- Ankylosing spondylitis, ICD10
- Ankylosing spondylitis
- Spondylopathies (FG)
- Spondyloarthritis
- Autoimmune diseases related-to ILD
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8672 | 3328 | 5319 |
| Only index persons | 8532 | 3302 | 5230 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.13 | 0.10 | 0.15 |
| Only index persons | 0.17 | 0.12 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 37.75 | 38.28 | 37.43 |
| Only index persons | 37.70 | 38.29 | 37.33 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1746 | 808 | 938 |
| Unadjusted period prevalence (%) | 0.36 | 0.29 | 0.43 |
| Median age at first event (years) | 39.46 | 38.45 | 40.34 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1816
- Matched controls
- 18160
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L04AC10
ATC
secukinumab; parenteral
73.9
307.7
192
29
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
32.3
307.7
646
305
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
67.6
307.7
406
77
L04AB06
ATC
golimumab; parenteral
111.2
307.7
393
45
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
140.4
307.7
1112
202
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
69.4
307.7
349
62
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
142.8
307.7
1140
212
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
20.1
307.7
717
570
L01BA01
ATC
methotrexate; systemic
28.8
307.7
436
197
A07EC01
ATC
sulfasalazine; oral, rectal
337.2
307.7
1678
632
L04AX03
ATC
methotrexate; systemic
27.1
307.7
1066
904
L04AB04
ATC
adalimumab; parenteral
60.5
307.7
699
186
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
44.7
307.7
408
117
L88
ICPC
Rheumatoid/seropositive arthritis
29.7
307.7
546
259
S01BA04
ATC
prednisolone; ophthalmic
25.6
307.7
235
105
L04AB01
ATC
etanercept; parenteral
83.6
307.7
538
91
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
7725.8
307.7
1812
891
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
13.7
307.7
535
536
M45
ICD-10 Finland
Ankylosing spondylitis
+∞
307.7
1816
32
L04AB05
ATC
certolizumab pegol; parenteral
76.1
273.3
147
21
S01BA01
ATC
dexamethasone; ophthalmic
14.0
261.1
253
207
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
39.6
253.4
156
43
H20.1
ICD-10 Finland
Chronic iridocyclitis
30.8
245.4
163
58
L04AA13
ATC
[U] leflunomide
16.8
229.7
198
131
M01AH01
ATC
celecoxib; oral
5.1
217.5
598
1581
L04AA11
ATC
[U] etanercept
81.8
216.1
115
15
H02AB06
ATC
prednisolone; systemic
4.7
213.3
1273
6008
WZA10
NOMESCO Finland
Extensive medical or dental certificate
17.9
197.9
164
100
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
14.1
193.0
183
143
S01FA04
ATC
cyclopentolate; ophthalmic
23.6
189.3
138
63
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
+∞
181.4
171
*
S01FA02
ATC
scopolamine; ophthalmic
33.1
168.8
109
35
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.9
163.1
428
1067
M01AC06
ATC
meloxicam; systemic, rectal
3.5
149.9
928
4178
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.7
149.5
718
2753
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
39.9
148.8
91
24
P01BA02
ATC
hydroxychloroquine; oral
5.6
143.3
308
643
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
1294.5
125.6
121
*
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
14.3
122.0
113
84
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
119.2
1028
5410
M01AH05
ATC
etoricoxib; oral
3.8
112.2
1481
9801
H02AB07
ATC
prednisone; oral
4.0
109.8
377
1129
L04AA17
ATC
[U] adalimumab
49.3
106.6
62
13
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
42.8
103.2
62
15
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
9.0
101.1
128
151
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
7.9
100.6
144
197
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
14.0
98.6
92
69
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
5.9
92.9
176
323
M13.9
ICD-10 Finland
Arthritis, unspecified
4.3
91.3
263
688
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
9.5
90.1
109
121
N02AX02
ATC
tramadol; systemic, rectal
2.6
84.4
940
5338
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.9
81.8
272
787
XX9XE
NOMESCO Finland
Other ultrasound examination
19.7
80.9
63
33
M01CB01
ATC
sodium aurothiomalate; parenteral
16.4
79.8
68
43
M01AH02
ATC
rofecoxib; oral
3.5
72.8
282
901
TNG10
NOMESCO Finland
Puncture of knee
11.8
71.9
74
65
NF1AA
NOMESCO Finland
Hip X-ray examination
4.3
71.7
199
503
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
5.7
71.6
139
260
ZX120
NOMESCO Finland
Intravenous
3.7
69.0
247
748
ZX140
NOMESCO Finland
Intra articular
14.1
64.9
60
44
L04AC13
ATC
ixekizumab; parenteral
28.2
64.9
44
16
L04AA01
ATC
[U] ciclosporin
11.2
64.6
69
64
M05BA04
ATC
alendronic acid; oral
4.9
64.4
151
333
L04AB02
ATC
infliximab; parenteral
12.5
63.6
63
52
M01AX01
ATC
nabumetone; oral
5.3
62.2
129
256
4AB02, ,
NOMESCO Finland
23.0
61.7
45
20
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.3
61.6
768
4412
M46.8
ICD-10 Finland
Other specified inflammatory spondylopathies
165.7
61.3
64
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
6.4
59.2
100
163
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.8
58.7
140
313
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
14.3
58.0
53
38
A02BC02
ATC
pantoprazole; systemic
2.4
57.4
1317
9587
298, ,
Kela drug reimbursment
20.0
55.6
43
22
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.2
55.2
946
6090
71240
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Spondylitis ankylopoietica
149.7
55.2
58
*
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
6.8
53.9
86
132
L04AX01
ATC
azathioprine; systemic
4.3
52.9
146
366
R4110
NOMESCO Finland
Physiotherapy
2.3
52.6
572
3063
3029
Kela drug reimbursment
Upadacitinib
17.6
52.4
43
25
M01AB01
ATC
indometacin; systemic, rectal
4.0
51.1
155
416
A02BC03
ATC
lansoprazole; oral
2.3
50.1
543
2894
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
3.7
49.6
170
497
H20
ICD-10 Finland
Iridocyclitis
12.3
48.9
49
41
UJF32
NOMESCO Finland
Coloscopy
2.3
48.6
486
2502
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.6
48.4
169
500
M01AE02
ATC
naproxen; oral, rectal
2.1
47.9
1147
8195
M01AX17
ATC
nimesulide; oral
2.3
46.8
439
2194
H15.1
ICD-10 Finland
Episcleritis
6.7
46.6
75
116
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.5
46.5
174
538
M01AB55
ATC
diclofenac, combinations; oral
4.0
46.5
141
378
K50.0
ICD-10 Finland
Crohn disease of small intestine
6.2
45.2
79
133
4AA12, ,
NOMESCO Finland
17.5
43.7
36
21
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
43.7
379
1826
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
43.7
678
4108
K50.8
ICD-10 Finland
Other Crohn disease
5.8
42.6
79
141
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.5
42.3
323
1468
H57.1
ICD-10 Finland
Ocular pain
3.7
41.7
137
388
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
10.5
40.5
45
44
H04.10
ICD-10 Finland
Dry eye syndrome
2.6
40.1
275
1187
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
5.6
40.1
77
142
M03BX02
ATC
tizanidine; oral
2.0
39.9
1288
9916
NF2AT
NOMESCO Finland
Injection to hip joint with ultrasound guidance
13.5
39.2
37
28
NH3EA
NOMESCO Finland
Feet X-ray examination with load
6.0
38.5
69
119
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.8
38.1
217
853
Z3229
NOMESCO Finland
Other healthcare associate professional
3.0
37.3
175
619
UJF30
NOMESCO Finland
Ileoscopy through colon
2.6
37.2
242
1016
S01BC03
ATC
diclofenac; ophthalmic
5.6
37.2
71
130
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
5.7
37.1
70
127
A07EA06
ATC
budesonide; oral, local oral
3.7
36.9
121
342
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
10.7
36.7
40
38
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.6
36.7
90
205
A07EC02
ATC
mesalazine; oral, rectal
3.1
36.7
161
548
NG1DA
NOMESCO Finland
X-ray of knees
6.0
35.4
63
108
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
5.4
34.5
69
132
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
8.4
34.3
45
55
M01AB05
ATC
diclofenac; systemic, rectal
1.9
34.1
1292
10193
Z3226
NOMESCO Finland
Physiotherapist
2.2
34.0
344
1752
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
8.2
33.8
45
56
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
4.8
33.4
76
163
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
32.9
817
5637
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.2
32.6
133
433
H02AB04
ATC
methylprednisolone; systemic
2.3
31.6
285
1382
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
6.9
31.5
49
73
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
9.2
31.3
38
42
K50.9
ICD-10 Finland
Crohn disease, unspecified
5.3
31.1
63
122
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
30.8
489
2920
H22.1
ICD-10 Finland
Iridocyclitis in other diseases classified elsewhere
162.8
30.8
32
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
4.5
30.6
75
171
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.4
30.1
234
1063
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
8.8
29.3
37
43
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
4.6
28.2
67
149
3640A
ICD-9 Finland
Disorders of iris and ciliary body, Acute and subacute iridocyclitis
285.8
27.8
28
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
27.6
861
6244
M35.7
ICD-10 Finland
Hypermobility syndrome
5.5
27.5
53
98
M46.0
ICD-10 Finland
Spinal enthesopathy
63.0
27.0
31
5
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.8
26.1
133
491
M01AB08
ATC
etodolac; oral
2.7
26.1
151
596
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
26.0
487
3040
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
5.7
25.8
48
86
S01BA07
ATC
fluorometholone; ophthalmic
5.1
25.4
54
109
A02BC05
ATC
esomeprazole; systemic
1.7
25.1
713
5003
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.4
24.8
182
804
N02BE01
ATC
paracetamol; systemic, rectal
2.1
24.7
1600
14081
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
24.7
605
4073
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
6.2
24.6
42
69
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.3
24.4
194
888
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
5.7
24.3
45
80
RK220, ,
NOMESCO Finland
21.0
23.9
35
17
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.3
23.6
93
296
NF1DA
NOMESCO Finland
X-ray of hips
5.2
23.4
48
94
M25.5
ICD-10 Finland
Pain in joint
1.7
23.4
668
4672
M13.8
ICD-10 Finland
Other specified arthritis
6.3
23.2
39
63
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
23.1
208
1001
S01ED01
ATC
timolol; ophthalmic
4.5
23.0
57
131
M54.5
ICD-10 Finland
Low back pain
1.7
22.7
726
5218
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.5
22.3
147
617
UJF92
NOMESCO Finland
Capsular endoscopy
4.0
22.2
63
161
M16.7
ICD-10 Finland
Other secondary coxarthrosis
7.7
22.1
31
41
RF120, ,
NOMESCO Finland
6.9
22.1
34
50
M54.8
ICD-10 Finland
Other dorsalgia
2.8
21.8
110
404
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.7
21.5
458
2944
K51.5
ICD-10 Finland
Left sided colitis
3.2
21.5
89
292
J01DB01
ATC
cefalexin; oral
1.9
21.1
1522
13341
L99
ICPC
Musculoskeletal disease other
4.0
21.1
61
158
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
4.6
20.4
49
110
M54.6
ICD-10 Finland
Pain in thoracic spine
2.2
19.9
178
853
SFA10
NOMESCO Finland
One-surface restoration
1.6
19.9
1064
8555
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
19.6
1296
10941
M01AC01
ATC
piroxicam; systemic, rectal
2.1
19.5
209
1075
K50.1
ICD-10 Finland
Crohn disease of large intestine
4.8
19.4
44
94
M03BC51
ATC
orphenadrine, combinations; systemic
1.7
19.4
512
3472
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.0
19.4
89
310
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
7.6
19.1
27
36
M01AE52
ATC
naproxen and esomeprazole; oral
3.2
19.0
75
239
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
19.0
646
4662
L04AC21
ATC
bimekizumab; systemic
55.6
18.9
22
*
K02.1
ICD-10 Finland
Caries of dentine
1.6
18.8
1173
9711
SFA20
NOMESCO Finland
Two-surface restoration
1.6
18.8
1156
9540
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
21.1
18.6
27
13
L84
ICPC
Back syndrome without radiat pain
2.6
18.6
110
438
L04AF03
ATC
upadacitinib; oral
14.3
18.6
31
22
L02
ICPC
Back symptom/complaint
2.0
18.4
220
1175
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
18.3
631
4558
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
25.3
18.2
25
10
RF410, ,
NOMESCO Finland
5.2
18.2
37
72
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
5.1
18.1
38
76
L04AD01
ATC
ciclosporin; systemic
3.9
18.0
53
139
F01
ICPC
Eye pain
3.1
17.9
75
248
RF420, ,
NOMESCO Finland
4.9
17.8
39
81
L04AA44
ATC
[U] upadacitinib
18.3
17.8
27
15
H26.3
ICD-10 Finland
Drug-induced cataract
7.4
17.4
25
34
RK210, ,
NOMESCO Finland
21.1
17.3
25
12
M07.2*L40.5
ICD-10 Finland
Psoriatic spondylitis
42.4
17.3
21
5
Z01.2
ICD-10 Finland
Dental examination
1.5
16.8
862
6765
A02BC01
ATC
omeprazole; systemic
1.7
16.6
400
2637
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
27.8
16.5
22
8
N03AX16
ATC
[U] pregabalin
1.7
16.3
376
2447
SPAT1325
SPAT
Vaccination
1.6
16.0
428
2891
N06AA09
ATC
amitriptyline; systemic
2.2
16.0
148
718
M05BB03
ATC
alendronic acid and colecalciferol; oral
5.4
15.9
31
58
J01MA02
ATC
ciprofloxacin; systemic
1.5
15.9
603
4421
Z3231
NOMESCO Finland
Registered nurse
1.6
15.6
430
2924
M13.0
ICD-10 Finland
Polyarthritis, unspecified
4.7
15.4
35
75
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.3
15.4
57
175
J01CA04
ATC
amoxicillin; systemic
1.7
15.3
1485
13249
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
15.3
633
4721
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
15.2
167
865
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
15.1
232
1344
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.5
15.1
1020
8400
D07AC01
ATC
betamethasone; topical
1.5
15.0
612
4543
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
15.0
352
2297
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.2
15.0
59
188
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
14.9
604
4476
R2110
NOMESCO Finland
Giving the first information
2.2
14.9
127
597
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
5.2
14.9
30
58
WZC30
NOMESCO Finland
Teaching
1.7
14.7
281
1734
WZA90
NOMESCO Finland
Other medical or dental certificate
1.6
14.7
422
2895
Z50.1
ICD-10 Finland
Other physical therapy
2.5
14.6
92
378
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.8
14.5
44
118
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
14.5
446
3109
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.6
14.4
47
133
M02.1
ICD-10 Finland
Postdysenteric arthropathy
19.3
14.2
21
11
H02AB08
ATC
triamcinolone; systemic
22.5
14.2
20
9
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
13.5
14.2
24
18
Z2221
NOMESCO Finland
Medical doctor
1.6
14.2
453
3182
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
4.5
14.0
34
77
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
14.0
1356
11922
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
3.9
14.0
40
103
M02AA07
ATC
piroxicam; topical
1.5
14.0
512
3704
RK250, ,
NOMESCO Finland
11.5
13.8
25
22
L34
ICPC
Musculoskeletal, Blood test
24.0
13.8
19
8
N03AX12
ATC
[U] gabapentin; oral
1.7
13.8
269
1670
RS221, ,
NOMESCO Finland
4.2
13.7
36
87
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
4.3
13.6
35
83
S01ED51
ATC
timolol, combinations; ophthalmic
2.4
13.6
94
403
L04AC05
ATC
ustekinumab; parenteral
5.9
13.5
24
41
M01CB03
ATC
auranofin; oral
11.0
13.5
25
23
S01FA06
ATC
tropicamide; ophthalmic
34.3
13.5
17
5
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
13.5
140
710
NE1BA
NOMESCO Finland
Pelvis extensive X-ray examination
5.3
13.4
27
52
M05BA07
ATC
risedronic acid; oral
4.4
13.4
33
76
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
3.2
13.2
52
166
N06AX21
ATC
duloxetine; oral
1.8
13.0
229
1379
M02.8
ICD-10 Finland
Other reactive arthropathies
6.2
12.9
22
36
TNF11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in hip joint
22.7
12.9
18
8
Z71.8
ICD-10 Finland
Other specified counselling
1.5
12.9
602
4566
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
4.9
12.9
28
58
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
12.9
370
2530
M08.1
ICD-10 Finland
Juvenile ankylosing spondylitis
50.4
12.8
15
*
M79.7
ICD-10 Finland
Fibromyalgia
2.6
12.6
73
288
NA6BM
NOMESCO Finland
Sacro-iliac joint MRI examination with 3 Tesla magnet
32.3
12.6
16
5
H20.8
ICD-10 Finland
Other iridocyclitis
6.2
12.5
21
34
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
12.4
125
627
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
2.6
12.3
69
268
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.0
12.3
132
677
RT272, ,
NOMESCO Finland
14.4
12.3
20
14
K07.60
ICD-10 Finland
Snapping jaw
2.2
12.1
109
523
R42
ICD-10 Finland
Dizziness and giddiness
1.6
12.1
313
2085
H26.2
ICD-10 Finland
Complicated cataract
4.2
12.0
31
74
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
5.7
12.0
22
39
M01AH03
ATC
valdecoxib; oral
2.2
11.9
103
488
A02BB01
ATC
misoprostol; oral
11.8
11.8
21
18
Z2446
NOMESCO Finland
Social worker
2.0
11.6
121
614
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
30.2
11.6
15
5
J01AA02
ATC
doxycycline; systemic
1.5
11.5
1303
11528
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
4.9
11.4
25
52
S01EC01
ATC
acetazolamide; systemic
3.5
11.4
38
109
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
11.4
206
1249
SFA30
NOMESCO Finland
Three-surface restoration
1.4
11.4
769
6208
R06.0
ICD-10 Finland
Dyspnoea
1.5
11.4
388
2748
H81.0
ICD-10 Finland
Ménière disease
3.7
11.4
36
100
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.1
11.3
47
155
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
11.3
333
2282
RT271, ,
NOMESCO Finland
35.2
11.3
14
*
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.5
11.2
71
293
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
11.2
373
2626
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
3.7
11.1
35
97
S01FA01
ATC
atropine; ophthalmic
11.2
11.0
20
18
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
11.0
130
690
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.5
11.0
37
107
B01AB05
ATC
enoxaparin; parenteral
1.5
11.0
426
3096
J01FF01
ATC
clindamycin; systemic
1.5
11.0
442
3238
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
10.9
224
1407
K51.8
ICD-10 Finland
Other ulcerative colitis
3.3
10.8
41
128
S01EA05
ATC
brimonidine; ophthalmic
3.7
10.8
34
94
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
10.7
705
5646
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.2
10.7
87
401
M02AA10
ATC
ketoprofen; topical
1.7
10.7
235
1500
L40.5
ICD-10 Finland
Arthropathic psoriasis
3.3
10.7
40
124
A01
ICPC
Pain general/multiple sites
1.8
10.6
160
920
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.0
10.6
108
545
WX290
NOMESCO Finland
Other blockage of nerve
1.4
10.4
945
7977
N20.0
ICD-10 Finland
Calculus of kidney
3.1
10.4
43
142
ZXE00
NOMESCO Finland
One hour or less
1.4
10.4
594
4638
NAJ12
NOMESCO Finland
Posterior reduction of fracture of cervical spine
32.7
10.3
13
*
H30.2
ICD-10 Finland
Posterior cyclitis
10.7
10.3
19
18
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.2
10.2
83
383
D06BB04
ATC
podophyllotoxin; topical
1.9
10.2
122
651
SDA03
NOMESCO Finland
Periodontal treatment
1.4
10.1
754
6149
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
10.0
722
5855
7168A
ICD-9 Finland
Other and unspecified arthropathies, Other specified arthropathy
40.3
10.0
12
*
RF210, ,
NOMESCO Finland
2.7
10.0
54
207
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
3.9
10.0
29
76
SPAT1263
SPAT
Sampling
1.4
9.9
626
4962
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
9.9
461
3464
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
9.8
993
8499
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
9.7
113
597
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
9.7
205
1294
E0000UV, ,
ATC
1.4
9.7
662
5313
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
55.3
9.7
11
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
9.6
340
2418
L28
ICPC
Limited function/disability (L)
1.6
9.6
211
1347
A02BA02
ATC
ranitidine; systemic
1.6
9.4
239
1579
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.4
9.4
517
3994
WW200
NOMESCO Finland
Immunization
2.5
9.4
58
237
SPAT1202
SPAT
Intra-articular injection
3.1
9.4
39
129
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
3.6
9.4
30
84
R50.9
ICD-10 Finland
Fever, unspecified
1.6
9.4
251
1679
L03
ICPC
Low back symptom/complaint
1.4
9.4
484
3698
J99.8*M45
ICD-10 Finland
Respiratory disorders in ankylosing spondylitis
+∞
9.4
9
*
M01AA01
ATC
phenylbutazone; systemic, rectal
+∞
9.4
9
*
7202A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Sacro-iliitis, not elsewhere classified
+∞
9.4
9
*
WX002
NOMESCO Finland
Sedation and analgesia
1.6
9.4
258
1738
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.9
9.4
117
634
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
9.3
174
1063
SPAT1251
SPAT
Organisation of medication
2.7
9.3
49
185
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
6.9
9.3
22
32
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.3
9.3
66
288
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.8
9.3
138
790
S18
ICPC
Laceration/cut
1.4
9.3
712
5814
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
9.3
920
7819
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
2.1
9.3
87
426
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.9
9.1
26
67
P01AB01
ATC
metronidazole; oral, rectal
1.4
9.1
633
5082
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.0
9.1
103
540
M46
ICD-10 Finland
Other inflammatory spondylopathies
36.9
9.0
11
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
8.9
351
2546
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
7.5
8.9
20
27
S12.2
ICD-10 Finland
Fracture of other specified cervical vertebra
4.2
8.9
23
55
ZX114
NOMESCO Finland
Intramuscular
3.3
8.9
33
102
R4120
NOMESCO Finland
Occupational therapy
1.9
8.9
111
602
C10AC01
ATC
colestyramine; oral
2.6
8.8
48
185
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
8.7
1279
11499
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
8.7
131
754
N02AC04
ATC
dextropropoxyphene; oral
2.9
8.7
40
141
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
3.8
8.6
26
70
M07.3
ICD-10 Finland
Other psoriatic arthropathies
3.8
8.6
26
70
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
3.8
8.6
26
70
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
8.6
71
331
D07AD01
ATC
clobetasol; topical
1.5
8.5
255
1750
H02BX01
ATC
methylprednisolone, combinations; systemic
2.4
8.5
55
231
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.8
8.4
124
708
F02
ICPC
Red eye
2.2
8.4
70
327
G47.3
ICD-10 Finland
Sleep apnoea
1.4
8.4
427
3247
4AB0X, ,
NOMESCO Finland
+∞
8.3
8
*
F29
ICPC
Eye symptom/complaint other
1.7
8.3
164
1018
ZYC01
NOMESCO Finland
Remote contact by phone
1.8
8.3
118
667
-44
ICPC
Preventive immunization/medic
1.9
8.3
95
501
NA6BG, ,
SPAT
7.1
8.3
19
27
M01AB16
ATC
aceclofenac; oral
2.7
8.2
44
168
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.6
8.0
46
182
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
8.0
60
269
M66.0
ICD-10 Finland
Rupture of popliteal cyst
3.9
8.0
23
60
N20.9
ICD-10 Finland
Urinary calculus, unspecified
2.5
7.9
50
207
R03AC02
ATC
salbutamol; inhalant
1.3
7.9
918
7910
ZY010
NOMESCO Finland
Hospital outpatient
1.9
7.9
104
574
M05BA06
ATC
ibandronic acid; systemic
4.0
7.9
22
56
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
13.1
7.9
13
10
J05AB01
ATC
aciclovir; systemic
1.4
7.9
334
2455
RS222, ,
NOMESCO Finland
4.1
7.8
21
52
J01MA12
ATC
levofloxacin; systemic
1.5
7.8
244
1688
R51.80
ICD-10 Finland
Headache
1.5
7.8
274
1942
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
7.8
1005
8785
UJH02
NOMESCO Finland
Anoscopy
2.2
7.7
63
292
L01BB02
ATC
mercaptopurine; oral
2.9
7.7
34
117
S01FB01
ATC
phenylephrine; ophthalmic
45.2
7.7
9
*
R35
ICD-10 Finland
Polyuria
1.9
7.7
98
535
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
2.4
7.7
49
204
L04AK01
ATC
leflunomide; oral
5.9
7.7
20
34
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.4
7.6
470
3681
A07EA02
ATC
hydrocortisone; rectal
2.5
7.6
45
181
L01
ICPC
Neck symptom/complaint
1.5
7.6
266
1883
RT171, ,
NOMESCO Finland
11.9
7.6
13
11
71490
ICD-8 Finland
Other specified forms of arthritis, Arthritis postinfectiosa NUD
11.9
7.6
13
11
1008, ,
NOMESCO Finland
25.1
7.6
10
*
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
4.1
7.5
20
49
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.2
7.5
64
302
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.7
7.5
135
817
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
7.5
140
856
XCH00
NOMESCO Finland
Eye pressure measurement
2.2
7.5
63
296
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
7.5
139
849
7209X
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Unspecified inflammatory spondylopathy
80.4
7.4
8
*
TNE11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in sacroiliac joint
80.4
7.4
8
*
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.6
7.4
194
1290
D01AE16
ATC
amorolfine; topical
1.7
7.4
147
914
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
7.4
496
3936
SPAT1260
SPAT
Consultation of another employee
1.5
7.4
224
1540
ZX112
NOMESCO Finland
Subcutaneous
2.9
7.3
33
115
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.3
812
6926
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
7.3
204
1378
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
7.3
356
2682
SPAT1153
SPAT
Removal of sutures
1.4
7.2
408
3149
J01FA10
ATC
azithromycin; systemic
1.3
7.2
993
8719
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.8
7.1
35
128
R5599
NOMESCO Finland
Other rehabilitation service
2.4
7.1
46
193
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.7
7.1
123
737
R5120
NOMESCO Finland
Preparation of an aid
2.6
7.1
38
146
M16.6
ICD-10 Finland
Other secondary coxarthrosis, bilateral
8.8
7.0
14
16
L15
ICPC
Knee symptom/complaint
1.4
7.0
364
2766
N02BF01
ATC
gabapentin; oral
1.6
7.0
164
1062
J01FA06
ATC
roxithromycin; oral
1.3
7.0
606
4986
R4180
NOMESCO Finland
Podiatric therapy
3.3
7.0
25
76
NA2AD
NOMESCO Finland
Thoracic spine CT examination
6.3
6.9
17
27
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.7
6.9
119
712
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.1
6.9
60
286
L85
ICPC
Acquired deformity of spine
13.8
6.9
11
8
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
6.8
284
2076
D94
ICPC
Chronic enteritis/ulcerative colitis
3.8
6.8
20
53
S21
ICPC
Skin texture symptom/complaint
1.5
6.8
207
1423
SFA00
NOMESCO Finland
Small restoration
1.5
6.8
229
1608
NA3BA
NOMESCO Finland
Lumbar spine extensive X-ray examination without contrast
9.3
6.8
13
14
R01AD58
ATC
fluticasone, combinations; nasal
1.3
6.8
474
3777
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
6.8
221
1542
KMAK, ,
NOMESCO Finland
1.3
6.7
920
8034
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.6
6.7
136
850
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
6.7
584
4803
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
6.7
301
2232
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
6.7
242
1724
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
6.7
338
2559
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.3
6.7
531
4312
K05.18
ICD-10 Finland
Chronic gingivitis
1.7
6.6
133
829
M17.5
ICD-10 Finland
Other secondary gonarthrosis
2.9
6.6
29
100
K92.1
ICD-10 Finland
Melaena
2.1
6.6
61
299
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.7
6.6
116
700
RF310, ,
NOMESCO Finland
10.1
6.5
12
12
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
3.0
6.5
27
90
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
6.5
1653
15760
R07.0
ICD-10 Finland
Pain in throat
1.6
6.5
133
834
L13
ICPC
Hip symptom/complaint
1.5
6.5
231
1641
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
6.4
375
2902
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
3.2
6.4
25
80
D01
ICPC
Abdominal pain/cramps general
1.5
6.4
188
1282
RT350, ,
NOMESCO Finland
14.4
6.4
10
7
WZA00
NOMESCO Finland
Concise certificate
1.7
6.4
117
713
M79.6
ICD-10 Finland
Pain in limb
1.3
6.4
698
5911
D99
ICPC
Disease digestive system other
3.8
6.4
19
51
-1, ,
NOMESCO Finland
1.3
6.4
559
4596
NDL52
NOMESCO Finland
Tenosynovectomy of hand
4.1
6.4
17
42
L17
ICPC
Foot/toe symptom/complaint
1.3
6.3
438
3482
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
6.3
391
3056
VALMI, ,
NOMESCO Finland
1.4
6.3
396
3102
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.8
6.3
94
541
A06AC51
ATC
ispaghula, combinations; oral
2.0
6.3
62
311
NA1AD
NOMESCO Finland
Cervical spine CT examination
1.9
6.3
71
374
L01CB
ATC
Podophyllotoxin derivatives
18.1
6.3
9
5
R20.2
ICD-10 Finland
Paraesthesia of skin
1.7
6.2
119
733
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
6.2
258
1884
S29
ICPC
Skin symptom/complaint other
1.4
6.2
285
2119
R52.2
ICD-10 Finland
Other chronic pain
2.0
6.2
64
326
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.2
392
3074
JN3AD
NOMESCO Finland
Abdominal CT examination
1.5
6.2
188
1293
D07XC01
ATC
betamethasone; topical
1.5
6.1
175
1188
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.5
6.1
160
1067
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
2.6
6.0
34
134
N20.1
ICD-10 Finland
Calculus of ureter
2.0
6.0
59
295
JF1AD
NOMESCO Finland
Small bowel CT
5.2
6.0
17
33
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.7
6.0
31
117
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1656
8066
12.95
315.21
14.8
6.7
0.59
0.57
e9/l
5.25
1592
7039
1656
8070
12.94
314.90
14.9
6.8
0.04
0.04
e9/l
2.66
1594
7039
1666
8262
13.31
307.94
14.9
6.8
2.13
1.97
e9/l
5.30
1620
7389
195
46
47.37
307.65
1.6
2.2
171.26
44.57
au/ml
—
29
5
233
66
40.35
307.65
1.8
2.5
9.19
9.26
mg/l
0.03
185
58
498
585
11.35
307.65
1.6
1.6
0.91
0.27
iu/ml
0.54
118
88
1665
8350
12.95
300.82
15.1
7.0
0.18
0.19
e9/l
1.96
1617
7409
1677
8925
12.48
269.89
17.2
10.2
3.79
4.06
e9/l
8.47
1620
7792
1528
7483
7.57
268.16
14.5
6.7
54.23
56.60
%
16.48
1509
7200
1535
7598
7.59
264.49
14.8
6.8
31.86
28.72
%
31.52
1514
7271
122
16
81.67
229.20
1.5
1.8
—
—
—
0
0
1747
11341
15.22
181.98
12.2
4.0
10.61
9.41
mm/h
4.44
1729
10769
1425
7990
4.64
172.20
5.4
3.3
0.00
0.00
estimate
0.80
328
1623
1431
8105
4.61
169.00
5.5
3.4
0.02
0.21
estimate
0.46
315
1509
1427
8077
4.58
168.40
5.4
3.4
9.52
7.62
estimate
0.10
332
1624
1722
11629
10.29
154.52
14.0
8.1
72.70
76.00
u/l
4.28
1705
11138
315
697
5.26
136.89
1.4
1.9
6.09
6.19
iu/ml
0.02
60
178
1217
7007
3.23
120.85
18.1
10.7
0.00
0.00
e9/l
0.81
1119
5751
109
81
14.25
117.66
3.0
3.5
7.07
8.96
mg/l
1.33
92
68
99
69
15.12
110.70
2.5
2.7
88.67
86.30
au/ml
0.01
12
11
188
359
5.73
95.16
1.8
1.4
—
—
—
0
0
173
336
5.59
85.79
2.2
1.6
5592.32
10752.44
e6/l
1.77
131
243
366
1256
3.40
85.22
2.0
2.1
0.00
0.03
estimate
1.06
118
311
795
4244
2.55
80.30
6.3
3.5
0.00
0.01
estimate
1.49
317
1528
247
695
3.96
77.12
2.1
2.3
0.00
1.05
estimate
0.51
100
244
1081
6758
2.48
76.02
3.0
2.5
74.16
73.82
nmol/l
0.16
1042
6299
998
6285
2.31
65.21
5.4
3.1
0.01
0.02
estimate
0.81
284
1371
494
2330
2.54
62.07
4.2
2.7
182.19
122.51
ug/g
2.44
431
1901
639
3541
2.24
54.41
6.0
3.3
1.02
1.45
kg/l
0.50
467
2323
1793
15717
12.12
50.23
26.0
13.3
14.96
22.28
mg/l
30.97
1678
12718
81
139
6.05
45.46
2.1
1.5
42.90
55.26
%
1.46
51
88
72
115
6.48
43.37
2.1
1.4
44.59
29.29
%
2.15
47
70
602
3531
2.05
42.10
2.8
2.2
2.76
2.67
mg/l
0.48
546
3092
196
711
2.97
40.01
1.3
1.4
—
—
—
0
0
739
4731
1.95
39.72
4.2
2.8
0.07
0.07
estimate
0.03
270
1317
539
3109
2.04
38.93
2.9
2.6
3.31
5.33
e6/l
5.31
501
2840
707
4604
1.88
34.91
3.6
3.2
32.40
69.69
e6/l
1.01
576
3459
881
6202
1.82
33.36
5.0
5.4
36.96
36.84
g/l
0.30
838
5883
621
3948
1.87
32.56
3.3
3.0
0.20
0.37
e6/l
2.85
491
2816
1711
15220
3.15
31.05
19.0
12.3
92.86
89.20
ml/min/173m2
14.58
1639
13984
847
5990
1.78
30.74
6.0
7.1
1.22
1.21
mmol/l
2.22
814
5611
414
2342
1.99
30.53
2.4
2.6
13.08
14.53
umol/l
3.85
391
2201
923
6766
1.74
28.91
6.0
7.6
1.22
1.21
mmol/l
2.01
820
5910
41
56
7.47
28.47
1.7
1.3
5.31
5.73
%
0.03
13
11
273
1361
2.18
28.06
2.1
2.7
11.15
10.63
g/l
1.46
256
1265
418
2459
1.91
27.09
2.8
2.7
0.69
0.87
e6/l
0.88
262
1234
1576
13695
2.14
26.74
27.0
16.3
13.61
13.40
%
10.05
1568
13528
224
1057
2.28
26.25
1.6
1.9
1.17
1.27
g/l
0.78
216
997
235
1137
2.23
25.91
2.0
2.4
0.25
0.31
e6/l
0.31
216
1079
58
128
4.65
24.61
1.9
1.2
10767.23
60327.98
e6/l
1.10
39
92
1799
16829
8.37
24.18
26.5
11.0
28.48
29.47
u/l
1.87
1790
16517
372
2185
1.88
23.90
2.3
2.6
2.37
2.38
g/l
0.06
350
2041
343
1997
1.88
22.52
2.4
2.7
22.49
24.54
%
2.03
322
1881
534
3557
1.71
22.19
1.5
1.5
2.83
2.36
g/l
5.15
364
2415
71
202
3.62
21.45
2.5
3.6
1.00
1.45
%
0.74
62
190
1130
9245
1.59
19.36
4.7
3.9
463.92
918.50
e6/l
0.38
12
114
977
7739
1.57
19.20
3.6
3.1
104.02
121.12
ug/l
2.64
944
7383
192
993
2.04
17.59
2.1
3.1
76.51
72.62
e9/l
0.72
138
714
969
7796
1.52
16.78
5.5
6.8
10.14
11.41
umol/l
2.44
919
7477
294
1829
1.72
15.00
1.7
1.7
1088.46
1158.19
nmol/l
0.76
235
1436
492
3567
1.52
13.17
1.8
1.6
19.23
19.72
nmol/l
0.34
440
3142
140
717
2.03
13.13
1.3
1.2
2.07
1.32
u/ml
0.15
16
52
113
534
2.19
13.07
1.4
2.0
1.49
1.50
g/l
0.01
90
469
747
5900
1.45
12.96
2.0
1.9
92.94
97.18
pmol/l
2.02
468
3301
173
966
1.87
12.60
1.8
1.7
—
—
—
0
0
547
4105
1.48
12.21
2.4
2.6
329.06
342.42
umol/l
2.76
498
3752
175
997
1.84
11.96
1.8
2.9
68.51
67.49
g/l
0.89
168
950
42
130
3.28
11.25
2.8
3.5
50.74
55.75
%
0.85
33
122
1805
17509
6.10
10.66
36.9
20.2
271.06
253.32
e9/l
25.68
1795
17259
1805
17521
5.98
10.39
36.8
20.1
4.54
4.64
e12/l
17.38
1793
17244
1805
17528
5.92
10.23
36.9
20.2
6.96
6.67
e9/l
6.14
1791
17235
748
6098
1.39
10.06
10.7
10.6
1.15
1.15
inr
0.15
629
5039
715
5790
1.39
10.00
3.5
3.5
33.64
35.35
u/l
0.22
680
5496
522
4009
1.42
9.92
1.3
1.3
1.06
1.72
u/ml
1.33
149
1190
91
444
2.10
9.76
1.4
1.3
—
—
—
0
0
229
1490
1.61
9.63
3.4
4.9
227.84
238.82
u/l
0.49
217
1424
321
2262
1.51
9.48
3.0
2.9
2.42
2.18
e6/l
0.14
164
1042
1660
15646
1.71
9.35
16.4
14.7
139.58
139.71
mmol/l
1.57
1645
15385
395
2911
1.46
9.31
1.3
1.3
10.83
8.41
u/ml
0.28
179
1234
52
203
2.61
9.27
1.3
1.3
—
—
—
0
0
49
186
2.68
9.23
1.4
1.4
—
—
—
0
0
1660
15695
1.67
8.60
16.6
14.8
3.93
3.96
mmol/l
4.38
1639
15396
489
3814
1.39
8.25
1.7
1.6
—
—
—
0
0
96
510
1.93
8.17
1.6
1.7
0.23
0.24
g/l
0.61
91
486
186
1209
1.60
7.84
2.4
2.4
22.61
19.99
au/ml
0.19
27
158
97
530
1.88
7.61
1.6
1.7
1.23
1.20
g/l
0.57
92
505
579
4690
1.34
7.56
2.6
3.4
2.35
2.35
mmol/l
0.66
543
4368
415
3196
1.39
7.46
1.3
1.3
22.83
25.21
iu/ml
0.22
115
919
230
1588
1.51
7.41
2.0
2.2
364.40
369.27
nmol/l
0.10
214
1499
543
4371
1.35
7.35
2.2
2.2
165.18
258.62
u/l
1.84
520
4187
70
354
2.02
6.90
1.5
2.5
0.00
0.02
g/l
0.64
64
330
76
401
1.93
6.66
1.6
2.6
0.22
0.89
g/l
2.27
69
365
59
287
2.09
6.47
1.8
1.6
—
—
—
0
0
13
16
8.17
6.33
1.7
1.6
3.86
2.93
mg/l
0.40
13
16
285
2130
1.40
6.03
2.0
1.9
—
—
—
0
0
319
2430
1.38
6.02
2.5
2.8
2.43
2.43
mmol/l
0.32
288
2203
455
3659
1.32
6.02
1.9
1.8
1.02
0.96
mg/l
0.15
337
2734
582
4841
1.30
6.01
2.8
2.7
60.17
59.99
u/l
0.01
548
4559
969
8601
1.27
5.91
5.2
5.3
6.37
6.60
mmol/l
3.83
923
8140
24
80
3.03
5.81
1.3
1.1
—
—
—
0
0
65
345
1.92
5.64
1.6
2.5
0.00
0.00
g/l
-0.00
56
306
111
695
1.64
5.49
1.3
1.3
165.00
226.38
miu/ml
1.03
39
319
36
154
2.36
5.42
2.3
2.6
33.06
32.81
pg
0.12
36
154
418
3378
1.31
5.25
3.0
3.2
521.85
929.69
ng/l
3.16
341
2774
38
169
2.28
5.25
1.1
1.1
—
—
—
0
0
623
5300
1.27
5.23
3.8
3.2
39.16
48.40
ng/l
0.23
390
3202
36
157
2.32
5.20
1.3
1.2
505.00
200.00
titre
—
6
25
244
1824
1.39
5.13
3.0
3.1
9.38
7.54
umol/l
0.34
213
1604
21
70
3.02
5.10
2.6
2.1
—
—
—
0
0
348
2755
1.33
5.05
1.8
1.6
31493906.86
30843099.08
pmol/l
0.01
308
2409
791
6950
1.24
4.93
2.7
2.7
—
—
estimate
—
0
0
75
436
1.75
4.91
1.3
1.1
—
—
—
0
0
75
436
1.75
4.91
1.3
1.1
—
—
—
0
0
74
431
1.75
4.82
2.6
3.0
—
—
—
0
0
31
132
2.37
4.75
1.2
1.1
—
—
—
0
0
20
70
2.88
4.50
2.6
2.1
—
—
—
0
0
20
70
2.88
4.50
2.6
2.1
—
—
—
0
0
20
70
2.88
4.50
2.6
2.1
—
—
—
0
0
23
87
2.66
4.49
2.0
2.2
0.69
2.21
u/field
1.64
13
58
31
137
2.28
4.39
1.2
1.1
—
—
—
0
0
31
137
2.28
4.39
1.2
1.1
—
—
—
0
0
69
409
1.71
4.26
1.9
1.7
—
—
—
0
0
1300
12159
1.24
4.17
3.8
4.2
14.73
14.53
pmol/l
2.46
1228
11454
99
647
1.56
4.17
1.8
1.8
—
—
—
0
0
37
180
2.08
4.17
1.8
1.5
—
—
—
0
0
114
769
1.51
4.16
1.8
2.2
38.14
40.29
u/l
0.74
108
709
19
68
2.81
4.12
1.8
1.6
1.43
3.92
u/field
0.56
14
57
1276
11919
1.24
4.10
3.4
3.3
—
—
—
0
0
31
142
2.20
4.06
1.2
1.1
—
—
—
0
0
41
210
1.97
4.03
1.2
1.2
—
12.77
—
0
12
1511
14405
1.29
4.00
4.6
5.0
1.67
1.80
mu/l
6.15
1439
13654
34
163
2.11
3.99
1.2
1.1
—
—
—
0
0
36
177
2.05
3.96
1.8
1.5
—
—
—
0
0
29
131
2.23
3.93
1.2
1.1
—
—
—
0
0
25
106
2.38
3.91
1.0
1.1
1602.97
1498.84
miu/ml
0.20
25
106
35
172
2.06
3.86
1.8
1.5
—
—
—
0
0
35
172
2.06
3.86
1.8
1.5
—
—
—
0
0
8
11
7.30
3.86
2.0
2.0
—
—
—
0
0
28
126
2.24
3.84
1.2
1.2
—
43.20
—
0
5
35
173
2.04
3.80
1.8
1.5
—
—
—
0
0
425
3571
1.25
3.78
2.5
2.3
—
—
—
0
0
184
1391
1.36
3.64
2.6
2.4
0.23
0.23
g/l
0.38
175
1315
15
51
2.96
3.57
3.1
2.5
—
—
—
0
0
15
51
2.96
3.57
3.5
4.2
—
—
—
0
0
62
376
1.67
3.57
1.7
3.1
2.23
2.02
index
0.07
30
214
334
2750
1.26
3.53
2.1
2.2
—
—
—
0
0
47
265
1.79
3.50
1.3
1.7
—
—
—
0
0
25
112
2.25
3.48
1.5
2.0
—
—
—
0
0
35
180
1.96
3.44
1.8
1.5
—
—
—
0
0
75
483
1.58
3.42
1.3
1.3
3.86
11.77
u/ml
—
8
74
232
1834
1.30
3.38
4.4
7.1
1.03
1.03
mmol/l
0.06
218
1736
25
114
2.21
3.35
2.3
2.2
47.50
33.35
mg/l
0.51
16
77
35
182
1.94
3.34
1.4
1.3
—
—
—
0
0
305
2503
1.26
3.31
2.0
2.1
—
—
—
0
0
200
1560
1.32
3.22
1.7
1.8
—
—
—
0
0
75
492
1.55
3.17
2.8
2.0
—
—
—
0
0
217
2710
0.77
3.14
2.0
2.0
3.70
3.69
ratio
0.03
169
2082
57
353
1.63
3.07
1.2
1.3
—
—
—
0
0
51
307
1.68
3.06
1.3
1.7
—
—
—
0
0
49
294
1.69
2.99
1.3
1.6
—
—
—
0
0
14
51
2.76
2.98
3.3
2.5
—
—
—
0
0
14
51
2.76
2.98
3.3
2.5
—
—
—
0
0
157
1198
1.34
2.95
2.8
2.5
74.37
75.16
ml/min/173m2
0.08
60
483
72
481
1.52
2.84
1.3
1.2
1.78
2.38
u/ml
—
5
42
75
507
1.50
2.80
2.3
2.2
0.65
2.26
ug/l
1.93
70
463
136
1028
1.35
2.74
3.3
4.0
1.22
1.23
mmol/l
0.48
125
883
45
273
1.66
2.66
1.2
1.2
—
36.67
—
0
6
25
126
2.00
2.66
2.4
1.8
—
—
—
0
0
25
126
2.00
2.66
2.4
1.8
—
—
—
0
0
25
126
2.00
2.66
2.4
1.8
—
—
—
0
0
188
1501
1.28
2.57
1.7
1.9
—
—
—
0
0
98
711
1.40
2.56
1.8
1.6
—
—
—
0
0
66
449
1.49
2.43
2.4
1.8
—
—
—
0
0
109
814
1.36
2.40
2.5
2.9
98.13
140.02
ng/l
1.23
98
720
442
3887
1.18
2.38
4.6
4.2
93.45
93.21
%
0.08
432
3813
18
85
2.13
2.29
1.5
1.4
3.62
6.88
u/l
0.90
13
70
124
955
1.32
2.25
1.1
1.1
—
—
—
0
0
9
29
3.11
2.22
1.0
1.1
—
—
—
0
0
68
476
1.45
2.20
1.8
2.4
10.03
10.72
mg/l
0.32
63
452
254
2144
1.21
2.14
1.9
2.3
30.11
29.48
s
0.88
248
2094
55
371
1.50
2.14
2.0
4.0
33.87
38.33
mg/l
0.28
45
307
55
371
1.50
2.14
2.0
4.0
44.52
58.38
mg/l
0.36
45
308
53
357
1.50
2.09
1.3
1.6
—
—
—
0
0
5
10
5.01
2.07
1.0
8.3
—
—
—
0
0
34
209
1.64
1.98
1.2
1.3
—
—
—
0
0
8
27
2.97
1.93
1.1
1.2
1.22
1.19
mmol/l
—
8
27
11
45
2.45
1.93
1.8
1.7
43.20
42.16
g/l
0.18
11
45
183
1515
1.23
1.89
3.2
2.7
47.36
70.59
u/l
0.32
154
1318
7
22
3.19
1.88
1.4
1.8
—
—
—
0
0
15
72
2.09
1.86
1.5
2.3
69.07
119.76
ng/l
2.25
15
72
23
129
1.79
1.86
1.2
2.0
—
—
—
0
0
97
744
1.32
1.85
2.9
3.0
1.97
1.55
mmol/l
0.62
72
555
284
2460
1.18
1.83
3.1
3.9
0.81
0.82
mmol/l
1.35
268
2358
45
303
1.50
1.81
1.4
1.5
—
—
—
0
0
170
2045
0.81
1.81
1.6
1.7
3.52
3.55
mmol/l
0.13
117
1409
51
353
1.46
1.79
1.2
1.2
—
—
—
0
0
281
2442
1.18
1.74
1.6
1.5
—
—
—
0
0
54
384
1.42
1.67
1.9
1.8
—
—
—
0
0
56
401
1.41
1.67
2.1
1.8
—
—
—
0
0
23
134
1.73
1.66
1.4
1.3
—
—
—
0
0
7
25
2.81
1.65
1.0
1.1
—
—
—
0
0
110
874
1.28
1.65
1.3
1.4
—
—
—
0
0
23
135
1.71
1.62
1.4
1.3
—
—
—
0
0
180
1514
1.21
1.61
9.2
10.4
1.02
0.81
mmol/l
0.33
150
1256
5
14
3.58
1.61
1.6
1.8
234.80
370.71
umol/24h
—
5
14
20
113
1.78
1.60
1.6
1.1
1.12
1.05
ratio
1.21
15
95
14
70
2.01
1.59
1.1
1.4
—
—
—
0
0
111
888
1.27
1.58
3.3
3.2
5.18
5.17
kpa
0.05
106
859
32
482
0.66
1.57
1.4
2.1
5.16
3.97
iu/l
—
9
209
181
1530
1.20
1.55
9.2
10.3
13.22
12.78
kpa
0.52
172
1481
12
57
2.11
1.55
2.4
3.6
1.84
1.88
ratio
0.05
12
51
11
51
2.16
1.50
1.4
1.4
15.95
16.27
umol/l
0.11
11
44
1523
14856
1.16
1.50
4.4
4.4
5.73
5.86
mmol/l
5.08
1452
14029
89
698
1.29
1.50
1.5
1.5
—
—
—
0
0
22
131
1.69
1.49
1.0
1.1
1.70
1.08
u/l
—
6
59
12
58
2.08
1.49
1.2
1.7
110.27
101.71
nmol/24h
0.13
12
58
180
1530
1.20
1.46
9.3
10.3
5.20
5.13
kpa
0.38
171
1480
15
80
1.88
1.44
1.3
1.9
1.64
4.56
nmol/l
—
10
68
11
53
2.08
1.38
1.7
1.6
—
—
—
0
0
175
1495
1.19
1.36
6.0
5.7
—
—
—
0
0
298
2655
1.15
1.36
4.2
3.5
603.54
560.38
ng/l
0.04
195
1798
46
333
1.39
1.33
2.0
3.8
1.51
3.49
ratio
0.77
26
179
161
1368
1.19
1.33
10.0
10.9
96.15
96.06
%
0.05
156
1324
13
69
1.89
1.28
1.2
1.4
—
—
—
0
0
6
131
0.46
1.28
1.8
1.6
8.02
7.82
mmol/l
—
6
125
544
5046
1.11
1.28
3.2
3.6
8.46
8.52
mmol/l
0.10
480
4411
8
36
2.23
1.24
1.9
1.1
91.63
98.22
%
—
8
36
152
1296
1.19
1.23
9.5
9.4
1.27
1.32
mmol/l
0.28
146
1272
116
965
1.22
1.22
3.3
4.3
72.98
83.34
ng/l
0.68
110
866
31
213
1.46
1.21
1.1
1.2
—
—
—
0
0
21
132
1.60
1.20
2.5
2.0
26.22
21.41
mg/l
—
9
59
89
1089
0.81
1.18
1.0
1.2
0.87
0.90
g/l
0.82
89
1089
40
293
1.37
1.12
2.5
2.1
138.68
135.21
g/l
0.40
31
225
556
5200
1.10
1.10
4.3
4.2
2.05
1.80
ug/l
0.74
509
4818
14
81
1.73
1.09
1.5
1.7
—
—
—
0
0
35
252
1.40
1.09
2.5
2.0
—
—
—
0
0
73
586
1.26
1.08
1.3
1.3
—
—
—
0
0
62
781
0.79
1.08
2.3
1.8
8.61
3.87
mg/l
0.83
51
565
14
82
1.71
1.05
1.4
1.4
169.21
174.49
mmol/24h
0.08
14
82
64
509
1.27
1.03
2.2
2.7
3.84
3.58
g/l
0.76
59
488
11
60
1.84
1.03
1.2
2.7
—
49632.89
—
0
9
97
810
1.21
1.01
12.2
12.9
24.76
24.28
mmol/l
0.75
92
801
139
1200
1.17
1.01
2.2
2.1
—
—
—
0
0
89
1065
0.83
0.98
1.0
1.1
1.47
1.50
g/l
0.44
89
1065
14
84
1.67
0.98
1.5
1.7
—
—
—
0
0
27
190
1.43
0.97
1.4
1.8
—
—
—
0
0
120
1030
1.18
0.94
3.3
2.2
6.94
8.26
ug/l
0.26
107
938
40
520
0.76
0.92
1.6
1.5
61.94
61.19
ug/l
0.03
34
425
26
361
0.72
0.92
1.8
1.5
0.24
0.35
nmol/l
1.05
16
282
32
235
1.37
0.92
1.4
1.5
—
—
—
0
0
11
63
1.75
0.90
1.2
2.0
—
—
—
0
0
11
63
1.75
0.90
1.2
2.0
—
—
—
0
0
61
494
1.24
0.88
1.2
1.1
3.97
4.12
—
9
93
86
1016
0.84
0.85
1.0
1.1
0.57
0.68
ratio
—
7
96
180
1608
1.13
0.84
4.0
4.3
31.19
30.27
%
0.67
146
1170
55
443
1.25
0.84
1.4
1.4
309.22
301.18
ug/g
0.08
28
244
59
482
1.23
0.80
4.2
3.9
11881.19
3015.01
u/ml
0.48
51
420
15
224
0.67
0.80
1.5
1.2
—
—
—
0
0
721
6899
1.07
0.80
1.9
1.9
1.42
1.47
mmol/l
0.96
631
6053
23
164
1.41
0.80
1.3
1.2
—
34.00
—
0
5
134
1179
1.15
0.80
3.3
4.8
193.68
18.05
ug/l
0.72
102
939
10
58
1.73
0.79
1.0
1.0
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
49
393
1.25
0.79
1.4
1.4
29.76
15.11
e6/l
0.32
42
286
50
402
1.25
0.79
1.6
1.4
11508.22
1797.50
e6/l
0.40
45
307
11
175
0.63
0.78
1.8
1.4
1.37
1.30
promille
—
6
142
12
74
1.63
0.78
1.6
1.3
261.17
517.40
u/l
0.69
12
65
14
90
1.56
0.78
1.5
1.6
—
—
—
0
0
0
28
0.00
0.76
0.0
2.0
—
0.46
—
0
20
163
1460
1.13
0.75
2.3
2.2
—
—
—
0
0
40
315
1.28
0.75
1.4
1.3
2.90
5.10
u/ml
0.54
21
110
38
481
0.79
0.75
1.6
1.5
1.09
1.17
ratio
0.22
26
297
38
481
0.79
0.75
1.6
1.5
0.94
1.14
ratio
1.04
26
296
38
481
0.79
0.75
1.6
1.5
1.00
0.97
ratio
0.21
26
296
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
1507
14836
1.09
0.73
5.2
5.4
36.85
38.44
mmol/mol
12.99
1454
14220
144
1282
1.13
0.73
5.2
9.3
7.91
8.41
mmol/l
0.53
136
1238
38
479
0.79
0.73
1.5
1.4
—
—
—
0
0
60
498
1.21
0.72
1.5
2.3
243.37
273.63
ug/l
0.10
52
474
6
109
0.55
0.72
4.8
10.0
—
154.21
—
0
39
74
867
0.85
0.70
1.7
1.6
1061.14
1000.02
mu/l
0.20
65
700
91
787
1.16
0.70
6.8
8.7
25.21
24.57
mmol/l
1.55
85
753
18
127
1.42
0.68
1.3
1.4
73.39
76.40
umol/l
0.36
18
127
151
1358
1.12
0.67
3.3
3.0
—
—
—
0
0
7
43
1.63
0.67
1.1
1.4
—
—
—
0
0
21
154
1.37
0.65
1.0
1.1
—
—
—
0
0
34
269
1.27
0.64
1.8
1.7
—
—
—
0
0
6
104
0.58
0.62
2.5
1.7
—
—
—
0
0
5
30
1.67
0.61
1.0
1.8
—
—
—
0
0
112
996
1.13
0.61
2.1
1.8
0.31
0.33
mg/l
0.14
51
521
8
52
1.54
0.59
1.0
1.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
6.03
—
0
22
8
53
1.51
0.58
1.1
2.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
8
54
1.48
0.57
1.3
1.4
—
—
—
0
0
8
54
1.48
0.57
1.3
1.4
—
—
—
0
0
29
229
1.27
0.57
1.9
2.2
6.09
6.10
umol/l
0.00
16
169
16
115
1.39
0.56
2.0
1.7
—
990549.00
—
0
11
8
55
1.46
0.56
1.3
2.1
—
—
—
0
0
5
89
0.56
0.56
1.2
1.5
59.95
33.21
nmol/l
—
5
70
20
150
1.34
0.56
1.5
1.6
11.88
12.26
umol/l
0.13
20
145
13
183
0.71
0.55
1.2
1.1
12.33
17.69
u/ml
—
6
81
12
82
1.47
0.54
1.1
1.4
74914.00
17028.45
e6/l
—
5
40
31
249
1.25
0.54
3.5
4.3
726.24
231.44
u/ml
0.37
25
235
9
62
1.45
0.53
1.7
1.2
—
64.44
—
0
9
1502
15197
0.93
0.52
4.1
4.0
1.31
1.35
mmol/l
1.84
1442
14439
14
100
1.40
0.52
2.3
1.6
17.43
27.86
umol/l
0.72
14
95
10
67
1.50
0.49
1.0
1.1
—
—
—
0
0
10
67
1.50
0.49
1.8
1.4
9.11
8.32
ug/l
—
10
67
51
437
1.17
0.48
1.2
1.2
278.69
259.81
u/ml
0.16
32
273
14
102
1.38
0.47
1.6
1.7
—
—
—
0
0
21
164
1.28
0.46
3.2
1.9
—
—
—
0
0
109
989
1.11
0.46
1.7
2.0
36.13
36.78
nmol/l
0.15
109
967
7
49
1.43
0.46
1.0
1.2
—
—
—
0
0
30
246
1.22
0.45
3.3
3.5
45.46
99.50
u/ml
0.31
30
241
466
4481
1.05
0.43
3.8
4.3
6.10
9.59
mg/mmol
2.01
293
2914
16
122
1.31
0.42
3.4
2.9
876.00
1216.99
mg
0.63
16
122
12
87
1.38
0.42
1.0
1.1
105.05
216.59
iu/ml
1.77
12
87
5
32
1.56
0.42
1.4
2.7
—
—
—
0
0
13
96
1.36
0.41
1.4
1.2
—
—
—
0
0
11
150
0.73
0.41
1.5
1.4
2.70
1.90
mmol/l
0.60
11
139
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
12
161
0.74
0.41
1.2
1.2
—
87.56
—
0
9
35
410
0.85
0.39
1.4
1.6
—
—
—
0
0
85
770
1.11
0.39
2.0
2.3
2362.85
6073.83
u/l
1.36
32
294
334
3195
1.06
0.38
2.7
2.7
0.70
0.68
ug/l
0.30
207
1691
16
124
1.29
0.38
2.0
1.7
—
—
—
0
0
51
578
0.88
0.37
1.5
1.4
—
—
—
0
0
9
68
1.33
0.37
1.0
1.3
—
—
—
0
0
15
117
1.28
0.35
1.3
1.4
38.04
32.86
g/l
1.27
15
104
26
218
1.20
0.34
1.1
1.4
181.24
214.12
pmol/l
0.34
26
218
11
82
1.34
0.34
4.4
3.2
55.20
166.36
umol/l
—
5
42
65
586
1.11
0.34
1.5
1.5
—
—
—
0
0
20
243
0.82
0.34
1.2
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
43
378
1.14
0.33
3.4
3.4
0.34
0.35
iu/ml
0.07
24
191
18
146
1.24
0.32
2.3
3.5
—
—
—
0
0
32
276
1.16
0.31
2.4
3.5
8.18
8.26
pmol/l
0.01
32
276
37
323
1.15
0.31
1.1
1.1
—
—
—
0
0
30
347
0.86
0.31
1.0
1.0
0.02
0.29
u/ml
2.11
12
109
124
1160
1.07
0.30
1.4
1.4
—
—
—
0
0
59
534
1.11
0.30
1.6
1.5
—
—
—
0
0
41
363
1.13
0.29
1.7
1.7
—
—
—
0
0
18
148
1.22
0.29
3.6
2.0
—
—
—
0
0
8
106
0.75
0.29
1.1
1.3
—
—
—
0
0
1223
12369
0.97
0.28
3.6
3.4
48.18
46.08
u/l
0.39
1177
11907
12
94
1.28
0.28
7.0
7.6
27.58
182.91
ug/l
—
6
67
1590
15997
0.95
0.28
4.7
4.6
1.43
1.41
mmol/l
1.83
1532
15282
11
85
1.30
0.28
4.8
3.0
27.50
394.55
ug/l
0.67
11
75
8
62
1.29
0.28
1.5
3.0
0.59
0.62
mmol/l
—
8
62
92
855
1.08
0.27
1.6
1.6
250.90
275.04
mu/l
0.24
83
792
9
119
0.76
0.27
2.0
2.3
1.21
1.19
mmol/l
—
9
119
47
424
1.11
0.26
1.3
1.5
—
17.12
—
0
7
15
181
0.83
0.25
1.8
1.4
1.51
1.39
nmol/l
0.21
15
168
9
74
1.22
0.25
2.1
2.0
—
—
—
0
0
126
1193
1.06
0.24
1.4
1.4
23.98
24.95
iu/l
0.12
109
1018
35
391
0.89
0.23
1.0
1.1
6.65
2.75
u/ml
0.37
20
190
23
199
1.16
0.23
1.0
1.1
—
—
—
0
0
35
313
1.12
0.23
1.3
1.2
4.19
4.15
u/ml
0.01
16
136
5
40
1.25
0.22
1.2
1.5
—
0.82
—
0
5
33
368
0.89
0.22
1.0
1.1
4.20
4.75
u/ml
0.10
18
162
27
238
1.14
0.22
1.1
1.1
107.15
98.51
%
0.93
27
226
11
135
0.81
0.22
3.1
4.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
1.45
—
0
11
0
11
0.00
0.21
0.0
2.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
1.58
—
0
5
0
10
0.00
0.21
0.0
1.5
—
0.42
—
0
5
0
10
0.00
0.21
0.0
1.5
—
5.03
—
0
5
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
8
105
0.76
0.21
2.3
3.0
46.13
45.90
%
—
8
105
8
105
0.76
0.21
4.5
6.1
7.50
7.99
%
—
8
105
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
20.40
—
0
8
0
13
0.00
0.21
0.0
6.0
—
495.23
—
0
13
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
9
111
0.81
0.20
1.2
1.5
—
—
—
0
0
9
115
0.78
0.20
1.6
2.3
—
688.54
—
0
23
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
99
1.21
0.19
1.0
1.1
—
—
—
0
0
126
1319
0.95
0.19
3.9
3.8
1.53
1.87
mmol/l
0.64
115
1143
1431
14227
1.03
0.17
29.1
16.4
331.98
334.13
g/l
16.83
1426
14155
7
62
1.13
0.17
1.1
1.5
0.59
0.48
e9/l
—
7
62
13
111
1.17
0.15
1.0
1.2
10.77
7.64
mm/h
0.27
13
111
1598
16040
0.97
0.15
4.8
4.7
4.68
4.74
mmol/l
1.76
1551
15397
12
102
1.18
0.15
3.3
3.3
760.17
713.55
u/ml
0.04
12
102
277
2835
0.97
0.15
1.9
1.9
1.54
1.45
%
0.93
249
2555
42
391
1.08
0.14
1.3
1.5
130.03
155.84
au/ml
—
6
115
13
112
1.16
0.14
2.0
1.7
—
—
—
0
0
58
549
1.06
0.13
2.9
3.0
1.38
1.35
mg/l
0.12
58
512
420
4134
1.02
0.13
3.5
3.5
22.17
21.08
%
0.76
188
1556
41
436
0.94
0.12
1.0
1.1
0.76
1.67
u/ml
0.96
24
211
18
162
1.11
0.12
1.3
1.3
0.17
0.84
u/ml
—
9
87
32
298
1.08
0.11
1.1
1.1
2.90
2.50
eliau/ml
—
6
152
10
86
1.16
0.11
2.6
1.5
29.90
28.48
umol/l
—
10
79
36
338
1.07
0.10
1.1
1.1
4.99
15.71
au/ml
3.18
12
114
17
154
1.10
0.10
1.1
1.1
—
—
—
0
0
24
222
1.08
0.10
1.0
1.1
—
—
—
0
0
81
838
0.97
0.09
4.4
3.7
24.08
24.32
mmol/l
0.41
81
830
48
502
0.95
0.09
1.1
1.1
2.00
2.18
u/ml
0.04
26
264
6
56
1.07
0.08
1.0
1.3
—
—
—
0
0
6
56
1.07
0.08
1.0
2.0
47.78
47.15
ug/l
—
6
56
30
318
0.94
0.08
2.2
2.4
97.78
139.86
ug/min
0.56
19
193
5
62
0.81
0.08
1.0
1.3
—
—
—
0
0
16
146
1.10
0.08
1.1
1.2
—
—
—
0
0
7
66
1.06
0.08
1.0
1.0
—
—
—
0
0
31
294
1.06
0.07
1.5
1.5
56.13
56.28
ug/l
0.01
31
294
11
122
0.90
0.07
1.8
2.3
106.00
105.70
mmol/l
0.08
11
122
11
122
0.90
0.07
1.8
2.3
4.15
4.01
mmol/l
0.53
11
122
8
92
0.87
0.06
1.1
1.2
—
—
—
0
0
103
1053
0.98
0.06
2.5
3.7
4.72
4.63
pmol/l
0.13
95
958
26
246
1.06
0.06
1.5
1.3
—
—
—
0
0
26
246
1.06
0.06
1.5
1.3
—
—
—
0
0
216
2131
1.02
0.06
2.5
2.5
14.73
14.16
nmol/l
0.59
200
1994
72
739
0.97
0.06
1.3
1.4
7.33
8.09
u/l
0.24
62
599
14
129
1.09
0.05
3.2
2.7
—
—
—
0
0
1613
16153
0.99
0.05
5.2
5.1
2.80
2.85
mmol/l
1.79
1563
15439
20
189
1.06
0.04
1.4
1.8
—
—
—
0
0
12
130
0.92
0.04
1.1
1.1
110.25
113.82
pmol/l
0.10
12
130
21
221
0.95
0.04
1.3
1.6
—
—
—
0
0
11
101
1.09
0.04
1.4
1.4
133.40
141.11
nmol/l
0.24
11
101
17
161
1.06
0.03
1.9
1.8
—
—
—
0
0
42
431
0.97
0.03
1.0
1.1
0.54
1.17
u/ml
0.90
18
180
65
662
0.98
0.03
1.6
1.7
35.35
12.67
u/ml
—
8
192
10
108
0.93
0.03
1.4
1.3
5.08
6.17
mmol/l
—
10
100
44
449
0.98
0.02
1.0
1.1
5.12
5.03
u/ml
0.01
25
241
12
113
1.06
0.01
1.8
1.2
—
—
—
0
0
28
286
0.98
0.00
2.9
3.1
18.03
25.76
mg/l
0.64
19
194
18
179
1.01
0.00
1.4
1.5
280.94
284.77
mosm/kgh2o
0.38
18
137
123
1234
1.00
0.00
1.1
1.2
74.10
133.48
u/ml
1.19
42
489
16
162
0.99
0.00
1.6
1.7
—
—
—
0
0
10
98
1.02
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
0.00
2.0
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
13.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
2.33
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
3.8
—
7.62
—
0
5
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
2.17
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
8.12
—
0
8
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
62
0.97
-0.00
6.0
3.4
1.17
1.52
%
—
6
62
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
97
0.93
-0.00
1.0
1.1
—
—
—
0
0
8
79
1.01
-0.00
1.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_ANKYLOSPON_STRICT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ANKYLOSPON_STRICT | 0.709 [0.53, 0.95] | 0.019 |
| Birth year | 0.993 [0.98, 1.0] | 0.138 |
During the follow-up period (1.1.1998 — 31.12.2019), 51 out of 2980 females with M13_ANKYLOSPON_STRICT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ANKYLOSPON_STRICT | 0.829 [0.71, 0.96] | 0.015 |
| Birth year | 0.988 [0.98, 1.0] | 0.014 |
During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 4769 males with M13_ANKYLOSPON_STRICT died.
Mortality risk
Mortality risk for people of age
years, who have M13_ANKYLOSPON_STRICT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.071% | 0.139% |
| 5 | 0.43% | 1.001% |
| 10 | 1.008% | 2.594% |
| 15 | 1.862% | 4.725% |
| 20 | 3.295% | 8.268% |
Relationships between endpoints
↥Index endpoint: M13_ANKYLOSPON_STRICT – Ankylosing spondylitis, strict definition
GWS hits: 13
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data