No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
1177 |
4. Check minimum number of eventsNone |
1177 |
5. Include endpointsNone |
1177 |
6. Filter based on genotype QC (FinnGen only) |
1077 |
Control definitions (FinnGen only)
- Control exclude
- I9_OTHHEART
Extra metadata
- Level in the ICD hierarchy
- 5
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Dronedarone medication
based on the number of shared cases.
Similar with more cases:
- Atrial fibrillation and flutter
- Cardiac arrhythmias
- Other heart diseases
- Other heart diseases, wide
- Cardiovascular diseases (excluding rheumatic etc)
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4159 | 1987 | 2166 |
| Only index persons | 4146 | 1983 | 2163 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.06 |
| Only index persons | 0.08 | 0.07 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 67.74 | 70.95 | 64.81 |
| Only index persons | 67.74 | 70.93 | 64.81 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1077 | 508 | 569 |
| Unadjusted period prevalence (%) | 0.22 | 0.18 | 0.26 |
| Median age at first event (years) | 67.81 | 70.36 | 65.53 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1103
- Matched controls
- 11030
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I48.2
ICD-10 Finland
Chronic atrial fibrillation
2017.6
321.1
296
*
C01BD07
ATC
dronedarone; oral
+∞
307.7
896
*
207
Kela drug reimbursment
Chronic arrhythmias
4503599627370496.0
307.7
1071
5
C01AA05
ATC
digoxin; systemic
214.1
307.7
447
35
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
307.7
766
*
I50.0
ICD-10 Finland
Congestive heart failure
187.0
307.7
160
10
TFP20
NOMESCO Finland
Cardiodefibrillation
4565.0
307.7
747
5
C01BD01
ATC
amiodarone; systemic
1879.1
307.7
374
*
C07AB07
ATC
bisoprolol; oral
50.3
307.7
1056
3406
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
13.2
307.7
554
782
XF404
NOMESCO Finland
Ambulatory ECG
39.7
307.7
415
165
K78
ICPC
Atrial fibrillation/flutter
189.0
307.7
499
48
B01AA03
ATC
warfarin; systemic
77.0
307.7
866
500
342
Kela drug reimbursment
Dronedarone
+∞
307.7
1103
*
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
731.6
307.7
585
17
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
17.0
307.7
701
1024
TFP34
NOMESCO Finland
Electrophysiological investigation
4366.1
307.7
327
*
C01BC04
ATC
flecainide; systemic
2533.3
307.7
451
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
14213.3
307.7
1081
38
I50.9
ICD-10 Finland
Heart failure, unspecified
74.3
307.7
348
68
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
27.9
307.7
337
171
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
+∞
307.7
316
*
B01AF02
ATC
apixaban; oral
54.9
307.7
656
287
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
440.7
307.7
396
14
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
529.6
307.7
310
8
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
6327.2
307.7
861
6
I48.1
ICD-10 Finland
Persistent atrial fibrillation
553.8
305.3
290
7
C07AA07
ATC
sotalol; systemic
34.7
288.7
188
65
I47.1
ICD-10 Finland
Supraventricular tachycardia
83.2
248.0
132
18
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
932.5
236.8
224
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
11.1
229.5
278
324
TFP35
NOMESCO Finland
Electroanatomical mapping
1308.3
225.1
212
*
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
+∞
224.9
208
*
K80
ICPC
Cardiac arrhythmia NOS
10.7
221.6
277
336
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
70.1
217.8
119
19
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
845.1
217.7
207
*
C08DA01
ATC
verapamil; systemic
19.8
216.0
175
104
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
+∞
212.6
197
*
I49.5
ICD-10 Finland
Sick sinus syndrome
617.0
211.5
203
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
6.3
198.0
508
1324
C03CA01
ATC
furosemide; systemic
5.9
191.3
586
1777
201
Kela drug reimbursment
Chronic cardiac insufficiency
32.8
188.1
123
42
B01AE07
ATC
dabigatran etexilate; oral
19.4
176.7
143
84
B01AF03
ATC
edoxaban; oral
45.7
168.2
100
24
WX404
NOMESCO Finland
Intravenous generell anesthesy
5.6
166.9
461
1255
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.7
164.9
880
4096
XF402
NOMESCO Finland
ECG with work load test
7.0
160.3
294
545
AN1
HP
Coronary angiography
6.8
154.4
291
553
I49.3
ICD-10 Finland
Ventricular premature depolarization
15.2
142.1
130
96
XF400
NOMESCO Finland
ECG with 12 standard connections
5.4
141.1
364
919
AR6
HP
Catheter ablation of arrhythmia, target: atrial fibrillation
+∞
140.7
132
*
C03DA01
ATC
spironolactone; oral
6.5
136.2
263
508
C07AB02
ATC
metoprolol; systemic
4.9
132.7
414
1215
K04
ICPC
Palpitations/awareness of heart
10.7
132.6
154
165
I35.0
ICD-10 Finland
Aortic (valve) stenosis
30.0
128.6
86
31
I49.1
ICD-10 Finland
Atrial premature depolarization
20.0
125.9
99
54
AQ2
HP
Electrophysiological electroanatomical examination
+∞
118.9
112
*
XF640, ,
NOMESCO Finland
20.4
118.2
92
49
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
166.5
114.7
119
8
AQ1
HP
Conventional electrophysiological examination
+∞
112.5
106
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
7.3
111.5
181
290
B01AF01
ATC
rivaroxaban; oral
5.0
110.0
294
750
I25.1
ICD-10 Finland
Atherosclerotic heart disease
4.2
108.9
426
1452
I34.1
ICD-10 Finland
Mitral (valve) prolapse
63.4
108.0
60
10
I50
ICD-10 Finland
Heart failure
31.8
100.9
66
22
I50.1
ICD-10 Finland
Left ventricular failure
1037.0
98.6
95
*
K05
ICPC
Irregular heartbeat other
10.9
94.6
106
107
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
3.6
91.0
466
1866
C08DB01
ATC
diltiazem; oral
7.5
90.6
140
211
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
+∞
87.7
83
*
R06.0
ICD-10 Finland
Dyspnoea
3.4
83.7
448
1827
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
+∞
83.4
79
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.5
80.6
399
1544
ZXD05
NOMESCO Finland
Urgent procedure
3.4
80.6
438
1796
AS4
HP
Physiological pacemaker insertion DDD (R)
+∞
79.1
75
*
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
+∞
79.1
75
*
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
8.4
75.1
102
132
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
22.2
73.9
55
26
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.7
72.6
297
1009
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
6.7
71.0
120
198
SPAT1097
SPAT
Recording of ECG
3.6
69.7
291
999
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
3.1
69.7
469
2144
R07.4
ICD-10 Finland
Chest pain, unspecified
3.1
69.2
466
2130
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
3.4
67.8
315
1156
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
+∞
67.4
64
*
R00.2
ICD-10 Finland
Palpitations
5.6
66.6
138
277
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
10.6
66.1
74
74
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
11.4
62.2
66
61
250, ,
Kela drug reimbursment
81.8
61.8
69
9
C01DA14
ATC
isosorbide mononitrate; oral
3.5
61.5
264
916
K99
ICPC
Cardiovascular disease other
9.9
61.3
72
77
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.4
61.2
276
988
C07AB03
ATC
atenolol; systemic
5.1
60.7
140
308
R00.1
ICD-10 Finland
Bradycardia, unspecified
9.6
60.5
73
81
ZXE00
NOMESCO Finland
One hour or less
2.8
59.9
544
2863
K84
ICPC
Heart disease other
8.8
59.7
77
93
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
10.6
58.9
66
66
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
13.4
57.5
55
43
I48.3
ICD-10 Finland
Typical atrial flutter
+∞
56.8
54
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
576.2
56.1
55
*
WX892
NOMESCO Finland
Monitored bed care
4.7
56.1
142
337
K77
ICPC
Heart failure
24.4
55.8
40
17
I20.09
ICD-10 Finland
Unstable angina
5.1
55.5
127
277
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
22.4
55.3
41
19
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
565.1
55.1
54
*
I48.4
ICD-10 Finland
Atypical atrial flutter
+∞
54.6
52
*
N02AJ06
ATC
codeine and paracetamol; systemic
2.6
54.2
591
3357
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
4.0
52.8
167
469
H03BB01
ATC
carbimazole; oral
6.2
50.4
90
156
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.9
50.2
305
1282
I47.2
ICD-10 Finland
Ventricular tachycardia
510.0
49.8
49
*
C09AA05
ATC
ramipril; oral
2.7
49.6
402
1957
AR5
HP
Catheter ablation of arrhythmia, target: atrial flutter
+∞
49.3
47
*
B01AB05
ATC
enoxaparin; parenteral
2.5
47.5
486
2633
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
79.6
47.4
53
7
I44.2
ICD-10 Finland
Atrioventricular block, complete
+∞
46.2
44
*
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
239.8
45.3
46
*
TFP40
NOMESCO Finland
Ablation treatment for a-v node re-entry activation
+∞
44.1
42
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.6
43.6
109
255
I20.99
ICD-10 Finland
Angina pectoris, unspecified
4.2
42.0
120
311
PH3AC
NOMESCO Finland
Flebography of internal organs with X-ray
+∞
41.9
40
*
XF600
NOMESCO Finland
Bloodpressure measurement
4.2
41.4
117
301
R02
ICPC
Shortness of breath/dyspnoea
3.0
41.3
213
810
SPAT1104
SPAT
Monitoring of emergency patient
3.9
39.3
124
345
81
HP
Angiography of the heart and coronary arteries
4.3
38.8
108
274
I42.0
ICD-10 Finland
Dilated cardiomyopathy
+∞
38.8
37
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
6.7
38.3
62
97
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
390.4
38.3
38
*
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
74.3
38.2
43
6
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
201.9
38.0
39
*
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
+∞
37.7
36
*
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
6.9
37.7
59
89
Z3231
NOMESCO Finland
Registered nurse
2.4
37.3
381
2017
Z2221
NOMESCO Finland
Medical doctor
2.4
36.3
359
1869
GD1LA
NOMESCO Finland
GD
70.8
36.2
41
6
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.2
36.2
552
3438
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
54.5
35.6
42
8
TFP32
NOMESCO Finland
Cathetric treatmen of cardiac arrythmia
+∞
35.6
34
*
PD5BD
NOMESCO Finland
Extensive CT of aorta
10.3
35.5
40
40
WX402
NOMESCO Finland
General anaesthesia
2.4
35.3
317
1580
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
3.5
34.9
128
394
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.6
34.7
126
385
R53
ICD-10 Finland
Malaise and fatigue
2.4
34.5
318
1600
G47.3
ICD-10 Finland
Sleep apnoea
2.4
33.8
313
1577
XFE00
NOMESCO Finland
Epicardial ultrasonography
8.6
33.2
43
52
A10BK03
ATC
empagliflozin; oral
2.9
32.6
180
705
R04.0
ICD-10 Finland
Epistaxis
3.4
32.6
130
422
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
4.0
32.0
96
257
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
31.3
466
2830
SPAT1249
SPAT
Treatment-related counselling outside office
2.1
31.2
494
3068
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
30.6
481
2973
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
39.3
30.4
38
10
A10BK01
ATC
dapagliflozin; oral
3.2
30.2
130
441
H02AB06
ATC
prednisolone; systemic
2.1
29.9
578
3846
R00.0
ICD-10 Finland
Tachycardia, unspecified
5.0
29.1
64
134
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
29.0
294
1526
J01DB01
ATC
cefalexin; oral
2.6
28.8
934
7530
SPAT1263
SPAT
Sampling
2.0
28.5
506
3249
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
+∞
28.2
27
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
28.2
270
1366
A02BC02
ATC
pantoprazole; systemic
2.2
27.6
827
6376
R31
ICD-10 Finland
Unspecified haematuria
2.6
27.6
175
733
M10.9
ICD-10 Finland
Gout, unspecified
3.2
27.5
117
394
Z50.0
ICD-10 Finland
Cardiac rehabilitation
10.3
27.5
31
31
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
+∞
27.2
26
*
C10AA05
ATC
atorvastatin; oral
2.0
27.1
603
4166
SPAT1260
SPAT
Consultation of another employee
2.3
27.0
246
1216
C01BA03
ATC
disopyramide; systemic
99.2
26.8
29
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
26.6
201
914
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
+∞
26.1
25
*
I49.0
ICD-10 Finland
Ventricular fibrillation and flutter
+∞
26.1
25
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.9
25.4
78
212
K29
ICPC
Cardiovascular sympt/complt other
3.7
25.2
82
232
AA1AD
NOMESCO Finland
CT of head and brain
2.0
24.7
397
2429
UJF32
NOMESCO Finland
Coloscopy
2.0
24.5
365
2174
SPAT1325
SPAT
Vaccination
1.9
24.4
463
2995
C10AX09
ATC
ezetimibe; oral
2.2
24.1
264
1401
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
24.1
434
2758
FPB22
NOMESCO Finland
Transvenous radiofrequency ablation of aberrant pathway or focus of heart
+∞
24.0
23
*
R2110
NOMESCO Finland
Giving the first information
3.5
23.8
86
261
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
4.4
23.8
61
145
K83
ICPC
Heart valve disease NOS
88.8
23.7
26
*
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
4.1
23.7
66
167
R42
ICD-10 Finland
Dizziness and giddiness
2.0
23.7
320
1837
I25.2
ICD-10 Finland
Old myocardial infarction
3.4
23.4
90
284
I49
ICD-10 Finland
Other cardiac arrhythmias
9.0
23.4
29
33
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
23.2
812
6389
C01BC03
ATC
propafenone; systemic
+∞
23.0
22
*
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
+∞
23.0
22
*
E05.89
ICD-10 Finland
Other thyrotoxicosis
122.6
22.7
24
*
N02BE01
ATC
paracetamol; systemic, rectal
3.2
22.5
1030
8979
I20.00
ICD-10 Finland
Unstable angina
4.8
22.4
51
110
FN1AD
NOMESCO Finland
CT of coronary arteries
6.6
22.3
36
56
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.4
22.1
168
763
C07AG02
ATC
carvedilol; oral
3.2
22.1
94
316
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
+∞
21.9
21
*
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
4.6
21.7
52
117
S18
ICPC
Laceration/cut
1.8
21.6
621
4530
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
3.8
21.4
68
189
AP1
HP
Catheterization of the left side of the heart
7.7
21.3
30
40
M04AA01
ATC
allopurinol; systemic
2.3
21.1
179
852
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
3.0
21.0
100
358
WX002
NOMESCO Finland
Sedation and analgesia
2.0
21.0
271
1520
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.2
21.0
214
1098
E66.01
ICD-10 Finland
Obesity due to excess calories
3.1
21.0
93
320
C10AA01
ATC
simvastatin; oral
1.8
20.9
587
4236
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
20.9
20
*
71
HP
Electrophysiological Special Examination
+∞
20.9
20
*
PD5AD
NOMESCO Finland
CT of aorta
5.9
20.7
37
64
FM1CD
NOMESCO Finland
Very extensive CT of heart
213.9
20.6
21
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
20.5
376
2376
C03AA03
ATC
hydrochlorothiazide; oral
2.5
20.5
135
573
SPAT1081
SPAT
Cardiorespiratory global assessment
3.0
20.4
94
331
H11.3
ICD-10 Finland
Conjunctival haemorrhage
3.3
20.3
79
251
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
20.2
307
1820
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
3.3
20.2
77
242
J01CA04
ATC
amoxicillin; systemic
2.0
20.1
861
7050
A12BA01
ATC
potassium chloride; oral
3.9
20.1
60
160
SPAT1251
SPAT
Organisation of medication
4.2
19.7
54
135
A02BC05
ATC
esomeprazole; systemic
1.8
19.3
480
3316
WX872
NOMESCO Finland
Intensive care
3.6
18.9
65
191
WX902
NOMESCO Finland
External defibrillation of heart
+∞
18.8
18
*
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
18.8
18
*
C09DX04
ATC
valsartan and sacubitril; oral
+∞
18.8
18
*
FPE40
NOMESCO Finland
Replacement of transvenous cardiac pacemaker electrode
+∞
18.8
18
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.1
18.8
81
274
R03AC02
ATC
salbutamol; inhalant
1.8
18.8
563
4094
I20.90
ICD-10 Finland
Angina pectoris, unspecified
3.9
18.8
56
149
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.4
18.7
145
662
C07AA05
ATC
propranolol; systemic
2.1
18.7
206
1086
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.3
18.6
159
757
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
3.0
18.4
83
288
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
18.2
151
710
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
6.8
17.9
28
42
R55
ICD-10 Finland
Syncope and collapse
2.3
17.9
147
688
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.4
17.9
65
198
Z71.8
ICD-10 Finland
Other specified counselling
1.8
17.9
377
2466
FN1CB
NOMESCO Finland
Coronary flow reserve measurement with pressure wire
4.3
17.8
47
114
I44.1
ICD-10 Finland
Atrioventricular block, second degree
67.7
17.8
20
*
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
+∞
17.8
17
*
FK1BT
NOMESCO Finland
Implantation of cardiac pacemaker with X-ray guidance
+∞
17.8
17
*
FPB10
NOMESCO Finland
Cryoablation of ectopic heart focus
+∞
17.8
17
*
205
Kela drug reimbursment
Chronic hypertension
1.8
17.7
353
2270
XF409
NOMESCO Finland
Other special ECG
37.4
17.7
22
6
TKC20
NOMESCO Finland
Catheterisation of bladder
2.7
17.6
96
370
C09AA04
ATC
perindopril; oral
3.1
17.5
77
264
I25
ICD-10 Finland
Chronic ischaemic heart disease
3.0
17.4
79
275
R00.8
ICD-10 Finland
Other and unspecified abnormalities of heart beat
7.2
17.4
26
37
C07AB04
ATC
acebutolol; systemic
6.0
17.0
30
51
H26.4
ICD-10 Finland
After-cataract
2.1
17.0
170
862
C10AA03
ATC
pravastatin; oral
2.4
17.0
122
538
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.8
16.9
89
337
-69
ICPC
Other reason for encounter NEC
3.4
16.8
60
181
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
+∞
16.7
16
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
16.5
458
3222
J01FF01
ATC
clindamycin; systemic
1.8
16.5
299
1860
-34
ICPC
Blood test
4.0
16.5
47
121
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.2
16.5
67
219
R5140
NOMESCO Finland
Monitoring the use of the aid
2.2
16.5
145
698
K79
ICPC
Paroxysmal tachycardia
40.7
16.4
20
5
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
3.2
16.3
65
210
M01AE01
ATC
ibuprofen; systemic, rectal
0.6
16.3
750
8714
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.4
16.2
117
516
FL1AC
NOMESCO Finland
Left cardioangiography
6.6
16.2
26
40
R07.3
ICD-10 Finland
Other chest pain
2.3
16.2
137
648
A98
ICPC
Health maint/preventive medicine
5.3
16.0
1082
10001
A11
ICPC
Chest pain NOS
2.3
15.9
126
579
WVA40
NOMESCO Finland
Initiation and monitoring of intravenous hydration
5.8
15.9
29
51
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
15.8
374
2510
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.9
15.8
78
285
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
4.0
15.8
45
116
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
33.9
15.8
20
6
J01AA02
ATC
doxycycline; systemic
1.8
15.7
857
7211
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
+∞
15.7
15
*
72
HP
Catheter ablation of arrhythmia
+∞
15.7
15
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
15.6
294
1848
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.1
15.5
67
227
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
15.5
532
3942
A46
ICD-10 Finland
Erysipelas
2.0
15.5
178
949
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
15.5
768
6271
L15
ICPC
Knee symptom/complaint
1.8
15.5
321
2074
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
15.3
205
1154
K22
ICPC
Risk factor cardiovascular disease
2.5
15.0
96
400
SPAT1310
SPAT
Counselling related to known health issue
1.7
15.0
378
2576
FPB32
NOMESCO Finland
Transvenous radiofrequency ablation of pulmonary vein pathway or focus
+∞
14.6
14
*
FPE96
NOMESCO Finland
Other implantation or replacement of transvenous cardiac pacemaker
+∞
14.6
14
*
AC4
HP
MVP
+∞
14.6
14
*
B01AC04
ATC
clopidogrel; oral
1.9
14.5
224
1320
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
15.6
14.4
23
15
FM1EE, ,
SPAT
6.1
14.4
25
42
N05BA04
ATC
oxazepam; oral
1.8
14.2
295
1899
M25.5
ICD-10 Finland
Pain in joint
1.7
14.1
356
2417
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
13.9
169
918
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
24.1
13.8
19
8
M25.0
ICD-10 Finland
Haemarthrosis
6.3
13.8
23
37
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
5.4
13.8
27
51
C07AB08
ATC
celiprolol; oral
3.5
13.7
48
143
J01FA06
ATC
roxithromycin; oral
1.6
13.6
420
3001
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
+∞
13.6
13
*
FFM10
NOMESCO Finland
Occlusion or excision of atrial appendage externally with a closing device
+∞
13.6
13
*
TFP33
NOMESCO Finland
Simple electrophysiological investigation (e.g. ventricular stimulation)
+∞
13.6
13
*
73
HP
Initial pacemaker installation
+∞
13.6
13
*
FPD96
NOMESCO Finland
Other operation for atrial fibrillation
+∞
13.6
13
*
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.9
13.5
184
1038
M03BX02
ATC
tizanidine; oral
1.6
13.5
628
4957
FPW96
NOMESCO Finland
Other operation for arhythmia or disturbance of impulse propagation
40.6
13.2
16
*
E66.00
ICD-10 Finland
Metabolic syndrome
2.8
13.2
67
249
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.6
13.0
79
321
C10AA07
ATC
rosuvastatin; oral
1.6
13.0
420
3026
N05CF01
ATC
zopiclone; oral
1.7
13.0
368
2566
C08CA13
ATC
lercanidipine; oral
1.9
12.9
199
1169
C08CA02
ATC
felodipine; oral
2.1
12.8
126
633
SPAT1255
SPAT
Intravenous administration of medicine
2.4
12.6
87
376
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
12.6
148
793
UKC02
NOMESCO Finland
Cystoscopy
1.8
12.5
218
1327
C01B
ATC
ANTIARRHYTHMICS, CLASS I AND III
+∞
12.5
12
*
AS2
HP
Ventricular pacemaker insertion VVI (R)
+∞
12.5
12
*
ARB
HP
Catheter ablation of arrhythmia: Cutiing or modification of the AV node
+∞
12.5
12
*
M10
ICD-10 Finland
Gout
2.7
12.5
66
250
Q21.10
ICD-10 Finland
Persistent ostium secundum
131.4
12.5
13
*
R01AD12
ATC
fluticasone furoate; nasal
1.7
12.4
283
1861
N02AX02
ATC
tramadol; systemic, rectal
1.6
12.3
485
3652
A02BC01
ATC
omeprazole; systemic
1.7
12.3
309
2085
WX722
NOMESCO Finland
PEEP
2.8
12.2
60
219
SPAT1285
SPAT
Provision of consultation response
2.6
12.2
72
289
SPAT1153
SPAT
Removal of sutures
1.6
12.1
400
2885
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.7
12.1
301
2024
R01AD08
ATC
fluticasone; nasal
1.7
12.1
284
1881
A04
ICPC
Weakness/tiredness general
1.9
12.0
174
999
AN4
HP
Balloon angioplasty and drug eluding stent
3.1
12.0
51
171
C08CA01
ATC
amlodipine; oral
1.6
12.0
493
3739
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.9
12.0
153
842
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
12.0
212
1296
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
12.0
332
2293
S80.0
ICD-10 Finland
Contusion of knee
2.4
12.0
81
347
R05
ICD-10 Finland
Cough
1.7
12.0
245
1562
C01BA01
ATC
quinidine; oral
47.2
11.9
14
*
R50.9
ICD-10 Finland
Fever, unspecified
1.9
11.8
161
907
A13
ICPC
Concern/fear medical treatment
4.0
11.8
33
84
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
9.8
11.8
23
24
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.0
11.7
139
747
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.3
11.6
93
429
K30
ICD-10 Finland
Functional dyspepsia
2.0
11.6
129
677
C10AA04
ATC
fluvastatin; oral
2.1
11.6
122
628
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
3.9
11.5
34
90
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
+∞
11.5
11
*
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
+∞
11.5
11
*
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
+∞
11.5
11
*
R05
ICPC
Cough
1.7
11.4
277
1847
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
11.4
173
1009
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
1.9
11.3
155
874
Q23.11
ICD-10 Finland
Bicuspid aortic valve
35.4
11.3
14
*
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.2
11.2
44
141
K01
ICPC
Heart pain
5.3
11.1
22
42
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
11.0
340
2402
-60
ICPC
Result test/procedure
2.4
11.0
76
329
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.9
11.0
50
175
M54.5
ICD-10 Finland
Low back pain
1.6
10.8
374
2710
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
10.8
281
1901
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
10.8
318
2221
SPAT1312
SPAT
General health counselling
1.6
10.8
332
2343
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
10.7
127
681
FM1BD
NOMESCO Finland
Extensive CT of heart
28.3
10.7
14
5
G44.2
ICD-10 Finland
Tension-type headache
1.9
10.7
136
748
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
60.6
10.6
12
*
J01MA12
ATC
levofloxacin; systemic
1.7
10.5
207
1300
L03
ICPC
Low back symptom/complaint
1.6
10.5
319
2241
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
3.8
10.5
32
87
FPD10
NOMESCO Finland
Surgical ablation of atrial fibrillation
+∞
10.4
10
*
FPJ02
NOMESCO Finland
Revision of ventricular pacemaker generator
+∞
10.4
10
*
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
+∞
10.4
10
*
AP3
HP
Catheterization of the right and left side of the heart
+∞
10.4
10
*
AH2
HP
Treatment of atrial fibrillation by maze surgery or its modification as the only procedure
+∞
10.4
10
*
M10.0
ICD-10 Finland
Idiopathic gout
2.9
10.4
49
175
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.7
10.4
197
1225
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.1
10.4
102
511
XF405
NOMESCO Finland
Symptom ECG
16.2
10.4
16
10
C09CA06
ATC
candesartan; oral
1.6
10.3
272
1844
ZX120
NOMESCO Finland
Intravenous
2.0
10.3
109
561
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.2
10.2
86
406
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.3
10.2
81
373
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
10.1
336
2406
R51.80
ICD-10 Finland
Headache
1.9
10.1
143
814
J01FA10
ATC
azithromycin; systemic
1.5
10.1
526
4153
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.4
10.1
67
285
SPAT1094
SPAT
Continuous Positive Airway Pressure
4.9
10.0
22
46
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
10.0
153
893
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
9.9
193
1207
N19
ICD-10 Finland
Unspecified kidney failure
2.9
9.9
46
163
R4110
NOMESCO Finland
Physiotherapy
1.6
9.9
313
2216
R23.3
ICD-10 Finland
Spontaneous ecchymoses
3.7
9.9
31
86
R01AD09
ATC
mometasone; nasal
1.5
9.8
418
3156
SPAT1301
SPAT
No procedures
1.5
9.7
353
2578
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
9.6
710
5997
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
4.8
9.6
21
44
J01MA02
ATC
ciprofloxacin; systemic
1.5
9.6
432
3300
C07AB12
ATC
nebivolol; oral
3.2
9.6
38
123
AN3
HP
Balloon angioplasty and metallic stent
3.2
9.6
38
123
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
7.2
9.5
22
31
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
9.5
480
3749
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.7
9.5
52
201
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
9.5
403
3036
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
9.5
291
2041
E66.8
ICD-10 Finland
Other obesity
2.9
9.4
43
151
I44.7
ICD-10 Finland
Left bundle-branch block, unspecified
17.7
9.4
14
8
I97.0
ICD-10 Finland
Postcardiotomy syndrome
30.3
9.4
12
*
FPG30
NOMESCO Finland
Implantation of cardioverter-defibrillator with ventricular electrode
+∞
9.4
9
*
FM1GD
NOMESCO Finland
CT of pulmonary arteries and left atrium
+∞
9.4
9
*
I42.8
ICD-10 Finland
Other cardiomyopathies
+∞
9.4
9
*
AB2
HP
AVR bio, stent
+∞
9.4
9
*
I45.6
ICD-10 Finland
Pre-excitation syndrome
+∞
9.4
9
*
K07
ICPC
Swollen ankles/oedema
2.4
9.4
65
282
R04.2
ICD-10 Finland
Haemoptysis
2.9
9.4
44
157
AN2
HP
Balloon angioplasty, including several vessels
3.0
9.4
42
146
R60.0
ICD-10 Finland
Localized oedema
1.8
9.3
158
950
R06.2
ICD-10 Finland
Wheezing
2.7
9.3
49
186
I44.0
ICD-10 Finland
Atrioventricular block, first degree
9.6
9.3
18
19
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
9.3
642
5333
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
9.2
441
3403
OAB50, ,
SPAT
2.0
9.2
109
585
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.6
9.1
29
81
FN1BT
NOMESCO Finland
Extensive endovascular dilatation of coronary (PTCA) arteries
3.6
9.1
30
86
SPAT1211
SPAT
Application of soft bandage
2.0
9.1
103
544
R07.2
ICD-10 Finland
Precordial pain
3.3
9.1
33
101
I20.01
ICD-10 Finland
Unstable angina
3.0
9.0
39
133
K64.1
ICD-10 Finland
Second degree haemorrhoids
3.3
8.9
33
102
H02AB07
ATC
prednisone; oral
1.8
8.9
146
868
I45.9
ICD-10 Finland
Conduction disorder, unspecified
24.2
8.9
12
5
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
8.9
126
717
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
8.9
151
909
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.0
8.8
91
464
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
8.8
144
855
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
4.7
8.8
20
43
E0000UV, ,
ATC
1.5
8.8
427
3293
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
8.8
143
848
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
8.8
497
3951
-44
ICPC
Preventive immunization/medic
1.9
8.8
107
579
61
HP
Catheterization and pressure measurement of the left side of the heart
4.2
8.7
23
56
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
2.4
8.7
57
241
AB1
HP
AVR mechanical
50.4
8.7
10
*
ZXD00
NOMESCO Finland
Emergency procedure
3.2
8.7
33
104
K02
ICPC
Pressure/tightness of heart
3.1
8.6
36
120
J01FA09
ATC
clarithromycin; systemic
1.5
8.6
293
2097
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.5
8.6
540
4374
WX780
NOMESCO Finland
Remote monitoring CPAP
2.5
8.6
51
206
M01AX05
ATC
glucosamine; oral
1.6
8.6
256
1780
A10
ICPC
Bleeding/haemorrhage NOS
7.0
8.6
20
29
K76
ICPC
Ischaemic heart dis without angina
2.9
8.6
39
137
T92
ICPC
Gout
3.3
8.5
32
100
A02BC03
ATC
lansoprazole; oral
1.5
8.3
310
2260
FPJ00
NOMESCO Finland
Revision of pacemaker pulse generator or electrode
+∞
8.3
8
*
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
+∞
8.3
8
*
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
+∞
8.3
8
*
42792
ICD-8 Finland
Symptomatic heart disease, Fibrillatio auricularis
+∞
8.3
8
*
K02.1
ICD-10 Finland
Caries of dentine
1.4
8.3
553
4521
K60
ICPC
Cardiovascular, Result test/procedure
7.1
8.3
19
27
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.3
8.3
60
266
J01DC02
ATC
cefuroxime; systemic
2.4
8.2
56
241
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
6.5
8.2
20
31
J01CA08
ATC
pivmecillinam; oral
1.5
8.2
362
2733
L13
ICPC
Hip symptom/complaint
1.6
8.1
248
1731
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.7
8.1
44
170
A60
ICPC
General and Unspecified, Result test/procedure
2.4
8.1
56
243
FPH96
NOMESCO Finland
Other removal of cardiac pacemaker or cardioverter-defibrillator
33.6
8.1
10
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.3
8.0
61
276
M79.6
ICD-10 Finland
Pain in limb
1.4
7.9
458
3634
S16
ICPC
Bruise/contusion
2.7
7.9
42
160
N05BA01
ATC
diazepam; systemic, rectal
1.8
7.9
135
812
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
2.1
7.9
76
378
N06AX11
ATC
mirtazapine; oral
1.5
7.9
346
2606
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
3.2
7.9
30
95
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
7.8
233
1616
SPAT1281
SPAT
Other administrative function
2.0
7.8
88
464
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
7.8
165
1054
J20
ICD-10 Finland
Acute bronchitis
1.9
7.7
107
604
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
45.3
7.7
9
*
F2680, ,
NOMESCO Finland
45.3
7.7
9
*
D07AC01
ATC
betamethasone; topical
1.5
7.7
387
2990
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
2.5
7.7
46
187
L17
ICPC
Foot/toe symptom/complaint
1.5
7.6
336
2529
I95.1
ICD-10 Finland
Orthostatic hypotension
2.4
7.6
53
231
SFA10
NOMESCO Finland
One-surface restoration
1.4
7.6
532
4363
K08.80
ICD-10 Finland
Toothache NOS
2.0
7.6
79
405
SPAT1254
SPAT
Administration of medicine
1.7
7.6
156
989
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.9
7.5
100
557
R13
ICD-10 Finland
Dysphagia
1.9
7.5
88
470
C09CA01
ATC
losartan; oral
1.5
7.5
306
2268
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
7.5
180
1187
N30.9
ICD-10 Finland
Cystitis, unspecified
2.1
7.5
72
359
E06.4
ICD-10 Finland
Drug-induced thyroiditis
80.6
7.4
8
*
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
80.6
7.4
8
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
7.4
114
665
T90
ICPC
Diabetes non-insulin dependent
1.5
7.4
294
2165
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.8
7.4
37
137
SPAT1353
SPAT
Intensive monitoring
13.5
7.4
12
9
N30.0
ICD-10 Finland
Acute cystitis
1.6
7.3
171
1118
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.4
7.3
50
216
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
+∞
7.3
7
*
21
HP
Aortic Valve Replacement (AVR)
+∞
7.3
7
*
FPG40
NOMESCO Finland
Replacement of pulse generator in transvenous cardioverter-defibrillator
+∞
7.3
7
*
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
+∞
7.3
7
*
42798
ICD-8 Finland
Symptomatic heart disease, Alia arrhytmia definita
+∞
7.3
7
*
AR1
HP
Catheter ablation of arrhythmia, target: AV node reentry activation (AVNRT)
+∞
7.3
7
*
AH3
HP
Treatment of arrhythmias, eg atrial fibrillation, in conjunction with other cardiac surgery
+∞
7.3
7
*
ATX
HP
Other pacemaker replacement or related action, such as cord removal or replacement
+∞
7.3
7
*
FFM30
NOMESCO Finland
Occlusion of atrial appendage internally by internal suture ligation
+∞
7.3
7
*
FPE24
NOMESCO Finland
Implantation of biventricular cardiac pacemaker, ventricular electrodes, CRT-P (VVIR)
+∞
7.3
7
*
I30.9
ICD-10 Finland
Acute pericarditis, unspecified
+∞
7.3
7
*
B04AB02, ,
ATC
3.5
7.3
24
69
-50
ICPC
Medication/prescr/renewal
2.4
7.3
47
198
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.1
7.3
64
308
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
7.2
68
336
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.5
7.2
266
1931
Z3226
NOMESCO Finland
Physiotherapist
1.6
7.2
189
1273
F1246, ,
NOMESCO Finland
30.2
7.2
9
*
W0X00, ,
SPAT
30.2
7.2
9
*
Q21.19
ICD-10 Finland
Atrial septal defect NOS
20.2
7.1
10
5
N17
ICPC
Vertigo/dizziness
1.6
7.1
157
1012
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.8
7.1
21
56
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
7.1
78
408
A10BJ06
ATC
semaglutide; parenteral
2.2
7.1
59
278
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
7.0
138
863
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.5
7.0
305
2284
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
7.0
75
389
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
7.0
187
1264
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.4
6.9
48
209
SFA20
NOMESCO Finland
Two-surface restoration
1.4
6.9
549
4574
T82
ICPC
Obesity
2.8
6.9
34
125
ANC
HP
Coronary artery pressure measurement (FFR, fractional flow reserve)
7.6
6.9
15
20
XG466
NOMESCO Finland
Sleep oxymetry
3.0
6.9
30
103
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
6.8
201
1387
R4110, ,
SPAT
1.6
6.8
162
1064
D19
ICPC
Teeth/gum symptom/complaint
1.5
6.8
293
2188
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.0
6.8
74
386
A06AC51
ATC
ispaghula, combinations; oral
2.1
6.8
60
290
R78
ICPC
Acute bronchitis/bronchiolitis
3.2
6.7
26
83
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
6.7
121
740
C02AC05
ATC
moxonidine; oral
2.2
6.7
55
258
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.9
6.7
82
446
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.6
6.7
38
151
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
4.0
6.6
18
45
R52.9
ICD-10 Finland
Pain, unspecified
1.8
6.6
109
649
K24
ICPC
Fear of heart disease
2.7
6.6
35
134
J01CF05
ATC
flucloxacillin; systemic
2.0
6.6
72
376
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.0
6.6
66
334
C09CA03
ATC
valsartan; oral
1.8
6.6
106
627
X58
ICD-10 Finland
Exposure to other specified factors
1.7
6.6
131
822
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
3.0
6.6
28
95
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.6
6.5
151
984
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
2.0
6.5
67
342
R06.5
ICD-10 Finland
Mouth breathing
1.8
6.5
90
508
R03BA05
ATC
fluticasone; inhalant
1.6
6.5
159
1050
A99
ICPC
Disease/condition unspecnature/site
1.7
6.5
123
761
Z01.2
ICD-10 Finland
Dental examination
1.4
6.5
434
3502
L01
ICPC
Neck symptom/complaint
1.6
6.5
158
1044
4019X
ICD-9 Finland
Essential hypertension, Unspecified
2.9
6.5
30
107
I47.0
ICD-10 Finland
Re-entry ventricular arrhythmia
70.2
6.4
7
*
XX9XB
NOMESCO Finland
Other X-ray examination with contrast
70.2
6.4
7
*
M35.3
ICD-10 Finland
Polymyalgia rheumatica
2.1
6.4
59
289
L08
ICPC
Shoulder symptom/complaint
1.5
6.4
252
1846
XF620
NOMESCO Finland
Examination of circulation with color method
14.4
6.4
10
7
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
6.4
115
703
R06AE07
ATC
cetirizine; oral
1.4
6.4
397
3163
XG410
NOMESCO Finland
Flow-volume spirometry
2.4
6.4
41
173
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
5.2
6.3
18
35
P06
ICPC
Sleep disturbance
1.7
6.3
116
712
N01
ICPC
Headache
1.9
6.3
85
476
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
1.9
6.3
77
418
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.0
6.3
64
326
FKD10
NOMESCO Finland
Replacement of mitral valve using biological prosthesis
+∞
6.3
6
*
4270A
ICD-9 Finland
Cardiac dysrhythmias, Paroxysmal supraventricular tachycardia
+∞
6.3
6
*
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
+∞
6.3
6
*
TFP43
NOMESCO Finland
Ablation treatment for atrial tachycardia
+∞
6.3
6
*
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
6.3
6
*
I34.8
ICD-10 Finland
Other nonrheumatic mitral valve disorders
+∞
6.3
6
*
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
+∞
6.3
6
*
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
+∞
6.3
6
*
4276B
ICD-9 Finland
Cardiac dysrhythmias, Premature beats[EXTRASYSTOLIA VENTRICULARIS]
+∞
6.3
6
*
AR2
HP
Catheter ablation of arrhythmia, target: extra pathway (WPW, AVRT, PJRT)
+∞
6.3
6
*
AP2
HP
Catheterization of the right side of the heart
26.8
6.2
8
*
D68.3
ICD-10 Finland
Haemorrhagic disorder due to circulating anticoagulants
26.8
6.2
8
*
3A064, ,
NOMESCO Finland
26.8
6.2
8
*
D64.9
ICD-10 Finland
Anaemia, unspecified
1.7
6.2
115
708
U02
ICPC
Urinary frequency/urgency
1.6
6.2
166
1121
A10BH05
ATC
linagliptin; oral
2.1
6.2
59
294
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.2
6.1
52
247
SPAT1262
SPAT
Handing over of treatment supplies
1.5
6.1
195
1367
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.4
6.1
41
176
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
12.6
6.1
10
8
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
2.5
6.1
35
140
R11
ICD-10 Finland
Nausea and vomiting
1.8
6.1
84
475
D64.8
ICD-10 Finland
Other specified anaemias
3.1
6.1
24
78
Z01.9
ICD-10 Finland
Special examination, unspecified
1.9
6.1
69
366
Z71
ICD-10 Finland
Persons encountering health services for other counselling and medical advice, not elsewhere classified
2.8
6.1
30
111
C08CA05
ATC
nifedipine; systemic
2.0
6.0
60
303
I95.2
ICD-10 Finland
Hypotension due to drugs
6.7
6.0
14
21
R5110, ,
SPAT
1.7
6.0
110
674
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
6.0
279
2106
R03BA08
ATC
ciclesonide; inhalant
1.9
6.0
78
432
SDA03
NOMESCO Finland
Periodontal treatment
1.4
6.0
383
3056
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
234
18
164.74
307.65
4.1
1.9
0.77
1.06
nmol/l
—
208
5
788
2707
7.69
234.65
4.9
1.9
1591.56
521.10
ng/l
13.80
712
2216
1004
4525
14.58
220.63
58.6
6.0
1.91
1.09
inr
190.36
920
3606
218
428
6.10
109.75
4.1
3.3
4.29
4.46
pmol/l
0.93
197
378
711
3658
3.66
93.67
7.6
3.0
19.66
173.57
ng/l
0.75
581
2778
243
626
4.70
88.46
3.6
1.8
256.10
89.48
ng/l
14.61
229
551
429
1766
3.34
77.98
6.8
3.0
135.56
497.78
ng/l
4.32
396
1449
903
5989
3.80
68.55
7.4
4.2
6.60
6.76
mmol/l
1.93
885
5657
386
1593
3.19
68.40
3.0
3.2
0.82
0.81
mmol/l
0.44
355
1491
270
920
3.56
65.04
4.0
2.7
5.91
5.73
kpa
2.07
264
898
262
885
3.57
63.87
4.0
2.7
1.97
1.92
mmol/l
0.08
245
757
239
770
3.69
62.51
4.0
2.3
4.46
4.37
kpa
0.24
233
752
816
5326
3.04
58.59
6.6
7.2
13.98
11.65
umol/l
7.40
780
5053
318
1288
3.06
56.76
2.3
2.1
21.56
23.28
%
1.53
297
1190
969
7123
3.97
54.16
6.6
4.1
15.52
14.99
pmol/l
8.37
881
6309
345
1503
2.89
53.54
2.4
2.2
12.71
13.16
umol/l
0.54
319
1384
330
1406
2.92
53.35
2.3
2.1
2.39
2.27
g/l
3.54
303
1282
325
1394
2.89
51.68
7.4
5.9
104.66
104.06
mmol/l
1.53
325
1394
810
5510
2.77
49.17
7.5
6.2
1.20
1.22
mmol/l
6.03
688
4695
747
4917
2.61
47.93
7.2
5.5
1.20
1.22
mmol/l
4.80
682
4469
197
658
3.43
47.90
3.4
2.0
9.38
6.18
ug/l
0.72
181
563
1008
7846
4.31
46.33
10.3
8.4
77.70
81.80
u/l
2.41
960
7360
342
1646
2.56
42.09
2.0
1.8
—
—
—
0
0
1061
8719
6.70
41.94
8.6
5.2
2.15
2.00
mu/l
2.64
967
7754
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
92
213
4.62
37.15
3.6
2.3
0.51
0.35
iu/ml
1.20
49
104
100
258
4.16
35.10
3.1
3.3
0.72
2.78
index
2.95
68
129
496
3015
2.17
33.93
3.8
3.2
0.45
0.45
e6/l
0.01
357
2191
198
805
2.78
33.47
4.3
5.2
9.40
8.92
mmol/l
0.47
192
765
506
3120
2.15
33.15
2.4
2.1
152.73
202.46
u/l
2.14
478
2939
264
1246
2.47
32.85
1.9
1.7
—
—
—
0
0
248
1152
2.49
31.84
1.8
1.7
—
—
—
0
0
427
2509
2.15
31.24
2.8
2.2
3.14
2.79
mg/l
1.64
362
2086
587
3887
2.09
31.24
3.5
2.7
129.36
158.09
ug/l
2.81
521
3518
1076
9337
7.23
30.73
27.3
15.1
24.26
27.27
mg/l
2.31
985
7623
760
5587
2.16
30.08
8.0
10.3
4.38
4.14
e9/l
1.91
617
4751
538
3483
2.06
30.06
3.9
3.3
144.13
84.55
e6/l
0.46
397
2646
865
6700
2.35
29.99
6.4
4.8
40.09
1932.93
e6/l
2.07
11
98
484
3047
2.05
28.87
3.5
3.3
39.32
33.87
u/l
0.55
443
2852
235
1122
2.39
28.07
8.2
6.4
11.33
12.60
kpa
3.10
226
1080
235
1122
2.39
28.07
8.2
6.4
5.07
5.10
kpa
0.14
226
1081
231
1102
2.39
27.61
8.2
6.5
0.86
0.77
mmol/l
0.13
194
909
418
2581
2.00
25.55
3.0
2.6
374.22
343.05
umol/l
6.97
329
2211
147
586
2.74
25.46
10.0
7.7
24.77
24.34
mmol/l
0.83
142
580
1054
9243
4.16
24.36
8.7
7.0
40.62
39.72
mmol/mol
2.79
956
8436
389
2403
1.96
23.28
2.7
2.5
3.86
5.04
e6/l
1.36
340
2172
216
1081
2.24
22.70
3.5
3.0
—
—
—
0
0
752
5803
1.93
22.20
4.3
3.2
55.81
55.07
u/l
0.09
686
5292
610
4404
1.86
22.19
13.9
10.9
0.00
0.00
e9/l
0.14
494
3528
1021
8874
3.03
22.16
5.5
4.4
1.28
1.28
mmol/l
0.09
904
7847
62
166
3.90
20.60
1.3
1.2
—
—
—
0
0
62
166
3.90
20.60
1.3
1.2
—
—
—
0
0
1092
9987
10.37
20.49
39.1
17.9
139.54
139.70
mmol/l
1.15
1087
9745
1092
10008
10.14
19.95
39.9
18.1
4.03
3.99
mmol/l
8.33
1087
9744
316
1919
1.91
19.24
3.5
2.9
0.85
1.28
e6/l
1.06
169
1017
1046
9337
3.33
19.17
30.4
15.6
70.58
75.90
ml/min/173m2
18.73
1019
8647
405
2665
1.82
19.08
5.1
3.8
63.80
92.73
%
65.21
400
2615
212
1124
2.10
18.98
2.9
2.8
7.47
8.76
umol/l
0.68
188
1009
1044
9322
3.24
18.86
6.6
5.3
1.35
1.48
mmol/l
18.96
939
8369
67
201
3.48
18.86
1.3
1.6
2.83
3.72
iu/l
0.50
14
79
1048
9395
3.32
18.45
6.7
5.4
4.13
4.58
mmol/l
34.82
946
8503
591
4386
1.75
18.11
2.5
2.2
—
—
—
0
0
228
1267
2.01
17.86
3.7
4.5
1.01
0.99
mmol/l
0.52
203
1172
875
7323
1.94
17.55
5.4
4.3
13.03
12.71
mm/h
0.25
793
6716
1088
10040
7.15
17.45
20.2
12.5
26.05
25.13
u/l
1.46
1061
9636
1048
9438
3.21
17.43
7.0
5.7
6.12
6.04
mmol/l
1.14
908
8431
213
1166
2.02
17.36
3.2
4.5
253.06
241.78
u/l
0.51
196
1102
456
3177
1.74
17.23
2.9
2.6
63.12
62.41
u/l
0.05
417
2911
289
1773
1.85
16.71
3.8
3.1
2.96
2.39
e6/l
0.30
144
868
307
1920
1.83
16.68
1.9
1.6
0.95
1.54
mg/l
3.81
200
1553
1058
9612
3.47
16.67
8.0
6.3
2.31
2.65
mmol/l
26.83
956
8663
620
4759
1.69
15.97
2.8
2.7
—
—
estimate
—
0
0
1093
10225
8.61
14.98
43.7
23.9
225.36
246.01
e9/l
28.42
1087
9919
1093
10226
8.59
14.96
43.7
23.9
6.88
6.74
e9/l
1.07
1079
9871
1093
10226
8.59
14.96
43.6
23.8
4.48
4.45
e12/l
0.90
1080
9873
379
2593
1.70
14.74
2.4
2.4
—
—
—
0
0
136
670
2.17
14.52
1.8
1.7
—
—
—
0
0
624
4874
1.65
14.37
4.7
4.7
35.14
35.40
g/l
0.58
575
4540
258
1597
1.80
14.20
1.3
1.3
14.96
40.98
iu/ml
10.06
55
467
172
943
1.98
13.75
1.9
2.5
73.02
66.28
e9/l
1.41
123
679
295
1938
1.71
13.05
1.9
1.7
1213.04
1131.12
nmol/l
0.58
201
1427
664
5349
1.61
12.80
4.7
4.0
6.80
4.43
estimate
0.13
172
1186
656
5289
1.59
12.44
4.7
3.9
0.00
0.00
estimate
-0.00
162
1152
264
1705
1.72
12.34
1.5
1.5
2.65
2.72
g/l
0.17
130
934
509
3882
1.58
12.17
3.3
3.4
7.00
7.45
mmol/l
1.57
381
3204
50
168
3.07
11.77
2.1
3.5
2.03
2.01
mmol/l
0.02
33
117
508
3917
1.55
11.30
4.0
4.1
4.98
5.00
mg/mmol
0.00
291
2379
450
3378
1.56
11.28
1.8
1.6
19.70
20.75
nmol/l
0.78
350
2743
661
5404
1.56
11.26
4.8
4.0
0.00
0.01
estimate
1.46
150
1103
122
638
2.03
11.07
3.8
2.9
5.17
5.07
kpa
0.52
114
612
237
1529
1.70
10.99
1.3
1.3
11.89
15.73
u/ml
0.26
69
503
289
1972
1.63
10.76
1.3
1.2
1.88
1.32
u/ml
0.22
73
477
54
209
2.67
9.86
1.2
1.5
—
—
—
0
0
35
106
3.38
9.78
1.3
1.6
—
—
—
0
0
153
900
1.81
9.72
2.9
3.5
1.23
1.23
mmol/l
0.43
127
769
96
485
2.07
9.56
1.6
1.4
—
—
—
0
0
135
777
1.84
9.19
3.6
2.8
58.33
63.75
ml/min/173m2
0.94
51
328
52
213
2.51
8.50
1.3
1.5
—
—
—
0
0
61
273
2.31
8.22
1.4
1.4
—
—
—
0
0
90
471
1.99
8.15
1.2
1.2
203.32
113.96
u/ml
0.97
25
161
155
962
1.71
8.14
2.7
2.4
40.39
40.94
u/l
0.03
122
816
609
5103
1.43
7.78
2.6
2.2
90.35
94.46
pmol/l
1.23
307
2600
96
539
1.86
7.07
3.7
2.7
1.66
1.43
mmol/l
0.22
68
385
475
3851
1.41
7.07
3.3
3.8
2.35
2.36
mmol/l
2.08
411
3452
78
411
1.97
6.95
1.8
1.8
1.25
1.97
ug/l
0.43
65
370
129
795
1.71
6.93
2.9
3.0
94.89
79.94
ng/l
1.36
102
685
132
819
1.69
6.92
2.1
2.4
342.27
377.61
nmol/l
0.96
118
759
517
4273
1.40
6.78
2.0
1.9
1.28
1.32
mmol/l
0.57
395
3498
37
144
2.62
6.75
1.3
1.6
—
—
—
0
0
157
1028
1.61
6.67
2.6
2.2
0.21
0.21
g/l
0.37
143
974
38
152
2.55
6.57
1.3
1.4
—
—
—
0
0
30
106
2.88
6.56
1.3
1.5
271.27
277.68
mosm/kgh2o
0.78
22
73
42
178
2.41
6.44
1.3
1.4
—
—
—
0
0
68
353
1.99
6.34
4.4
2.9
24.87
24.61
mmol/l
0.33
62
327
45
199
2.31
6.29
2.2
1.7
—
—
—
0
0
56
272
2.12
6.24
1.7
1.5
—
—
—
0
0
190
1323
1.53
6.17
10.3
6.0
—
—
—
0
0
159
1070
1.57
6.01
2.0
2.2
196.21
143.78
ug/g
0.60
113
844
70
378
1.91
5.84
2.1
1.8
—
—
—
0
0
542
4609
1.35
5.54
2.5
2.3
79.08
80.50
nmol/l
0.53
434
4017
112
710
1.64
5.42
1.8
1.5
—
—
—
0
0
377
3058
1.35
5.17
4.7
3.9
0.00
0.00
estimate
0.50
159
1059
66
365
1.86
5.15
1.3
1.6
6.50
6.89
iu/ml
—
7
92
65
361
1.85
5.01
2.5
2.6
—
—
—
0
0
78
466
1.73
4.73
1.7
1.6
1.30
1.56
g/l
2.06
59
403
300
2377
1.36
4.72
1.8
1.7
43555989.52
23120918.41
pmol/l
0.19
225
1942
10
14
7.20
4.66
5.5
1.1
1.22
1.15
mmol/l
—
10
14
50
262
1.95
4.61
1.9
1.6
10861.85
13258.13
e6/l
0.21
34
179
460
3897
1.31
4.52
4.9
4.0
0.01
0.03
estimate
1.17
147
937
24
93
2.62
4.49
1.6
1.3
883.47
12913.72
e6/l
0.59
17
58
332
2708
1.32
4.23
4.3
3.5
0.01
0.00
estimate
0.22
136
920
46
244
1.92
4.12
1.6
1.8
—
—
—
0
0
26
111
2.37
4.02
1.4
1.5
—
—
—
0
0
22
87
2.56
3.98
1.6
1.3
11326.50
83669.62
e6/l
1.28
12
45
112
769
1.51
3.88
1.7
1.4
—
—
—
0
0
132
943
1.45
3.76
2.0
2.9
65.27
66.83
g/l
1.55
115
852
61
366
1.71
3.69
2.1
1.7
—
—
—
0
0
73
465
1.61
3.53
5.7
4.4
1.51
1.46
%
0.15
67
441
136
996
1.42
3.40
1.4
1.3
—
—
—
0
0
43
240
1.82
3.35
1.7
1.3
—
—
—
0
0
61
383
1.63
3.15
2.3
3.3
56.49
178.54
mg/l
0.42
51
333
17
67
2.56
3.13
3.4
4.1
250.18
112.06
nmol/l
0.40
17
67
59
368
1.64
3.13
1.7
1.6
37.75
40.81
u/l
0.55
48
322
66
424
1.59
3.11
2.1
2.7
0.78
1.62
g/l
1.10
52
357
14
50
2.82
3.09
1.6
1.5
—
—
—
0
0
54
331
1.66
3.07
1.7
1.4
250.54
268.68
ug/g
0.38
36
189
60
381
1.61
2.98
2.3
3.3
29.86
79.87
mg/l
1.00
49
332
17
70
2.45
2.89
1.4
1.4
—
—
—
0
0
25
122
2.07
2.88
1.1
1.4
—
—
—
0
0
29
150
1.96
2.87
1.3
1.4
—
—
—
0
0
25
123
2.06
2.83
1.1
1.4
—
—
—
0
0
40
231
1.76
2.83
1.5
1.9
136.17
129.84
g/l
0.70
24
172
66
435
1.55
2.81
2.3
2.6
3.16
2.99
g/l
0.54
57
384
17
71
2.42
2.81
2.5
2.7
—
—
—
0
0
25
124
2.04
2.77
1.1
1.4
—
—
—
0
0
34
189
1.82
2.73
1.2
1.3
—
—
—
0
0
25
125
2.02
2.72
1.1
1.4
—
—
—
0
0
78
538
1.48
2.70
3.4
3.8
1.02
1.02
ratio
2.89
71
493
23
112
2.08
2.68
1.6
1.6
55.25
60.29
%
0.25
12
70
23
113
2.06
2.63
1.1
1.5
19.27
29.12
ng/l
1.47
23
113
18
81
2.24
2.55
1.1
1.1
—
—
—
0
0
21
101
2.10
2.54
1.0
1.1
14.02
14.64
au/ml
—
5
17
53
341
1.58
2.53
2.4
3.2
1.56
3.12
ratio
0.78
31
201
24
122
1.99
2.51
1.1
1.4
—
—
—
0
0
29
158
1.86
2.50
1.4
1.3
—
—
—
0
0
7
16
4.40
2.47
1.1
1.1
—
—
—
0
0
20
96
2.10
2.44
1.3
1.2
—
—
—
0
0
59
393
1.53
2.43
1.1
1.1
—
—
—
0
0
24
124
1.96
2.41
1.1
1.4
—
—
—
0
0
47
298
1.60
2.39
1.2
1.3
—
—
—
0
0
15
64
2.36
2.39
1.0
1.3
—
—
—
0
0
15
64
2.36
2.39
1.0
1.3
—
—
—
0
0
15
64
2.36
2.39
1.0
1.3
—
—
—
0
0
281
2392
1.23
2.37
3.4
3.2
2.45
2.46
mmol/l
1.07
245
2164
40
245
1.66
2.34
2.8
2.2
60.46
73.84
ug/min
0.11
22
139
54
357
1.54
2.31
2.2
2.7
0.01
0.06
g/l
0.92
48
316
67
464
1.47
2.31
2.3
2.6
3.59
3.84
g/l
0.88
59
413
486
4375
1.20
2.30
6.5
6.2
3.11
2.91
ug/l
0.08
426
3963
67
465
1.47
2.29
2.3
2.6
4.03
4.21
g/l
1.12
59
414
67
465
1.47
2.29
2.3
2.6
7.48
7.48
g/l
0.01
59
413
23
121
1.92
2.22
1.0
1.1
323.31
251.80
u/ml
0.50
13
66
22
114
1.95
2.21
3.4
1.8
106.14
104.80
mmol/l
1.09
22
114
22
114
1.95
2.21
3.4
1.8
4.07
4.00
mmol/l
0.38
22
114
8
24
3.35
2.18
1.1
1.8
0.62
0.60
mmol/l
—
8
24
121
939
1.32
2.16
1.3
1.3
—
—
—
0
0
59
407
1.48
2.10
1.9
2.6
9.19
10.61
g/l
2.35
51
352
20
103
1.96
2.06
3.3
3.3
15.70
11.29
index
—
10
55
11
44
2.52
2.01
1.2
1.3
—
—
—
0
0
37
232
1.62
2.01
4.3
1.9
86.35
91.78
%
0.68
37
225
20
104
1.94
2.01
1.2
1.1
—
79.38
—
0
8
48
321
1.52
1.99
1.4
1.6
0.32
0.33
mg/l
0.05
16
145
51
346
1.50
1.98
2.2
2.7
0.00
0.00
g/l
-0.00
44
299
44
289
1.54
1.98
1.3
1.6
—
—
—
0
0
21
112
1.89
1.97
3.4
4.4
—
—
—
0
0
21
112
1.89
1.97
7.6
6.1
12.58
11.71
mg/l
0.31
16
105
21
112
1.89
1.97
3.5
1.8
1.20
1.19
mmol/l
0.50
21
112
7
21
3.35
1.96
1.3
1.4
—
—
—
0
0
10
39
2.58
1.94
1.0
1.4
—
—
—
0
0
10
39
2.58
1.94
1.3
1.4
189.00
171.32
mmol/24h
—
10
39
10
39
2.58
1.94
1.0
1.4
—
—
—
0
0
10
39
2.58
1.94
1.0
1.4
—
—
—
0
0
10
39
2.58
1.94
1.0
1.4
—
—
—
0
0
31
188
1.67
1.92
1.1
1.1
5.50
4.42
—
5
12
12
52
2.32
1.88
4.0
1.5
76.50
80.62
umol/l
0.33
12
52
307
2695
1.19
1.86
3.9
3.5
0.71
0.81
ug/l
1.33
226
1893
5
12
4.18
1.82
5.2
5.5
4.62
5.47
kpa
—
5
12
17
87
1.97
1.80
1.0
1.5
—
—
—
0
0
47
322
1.48
1.76
1.3
1.2
—
—
—
0
0
78
586
1.36
1.76
1.3
1.4
40.87
71.76
au/ml
—
7
45
8
31
2.59
1.66
1.1
1.7
—
—
—
0
0
7
25
2.81
1.65
1.3
1.3
11.43
385.56
ug/l
—
7
19
5
14
3.58
1.61
1.2
1.4
—
—
—
0
0
25
151
1.67
1.61
1.7
1.8
28.57
24.36
mg/l
—
7
49
24
145
1.67
1.55
1.2
1.2
—
—
—
0
0
116
940
1.26
1.54
2.1
2.3
12.77
13.55
nmol/l
0.45
105
853
11
51
2.17
1.51
1.2
1.4
15.11
15.04
umol/l
0.01
11
44
39
267
1.48
1.50
1.2
1.6
—
—
—
0
0
82
641
1.30
1.45
2.5
2.6
10.61
18.64
au/ml
—
8
45
11
52
2.13
1.44
1.6
2.7
7.65
7.37
mmol/l
0.15
11
52
28
180
1.57
1.44
2.1
1.7
3.94
4.75
mmol/24h
0.76
23
155
15
81
1.86
1.40
1.0
1.6
—
—
—
0
0
35
240
1.47
1.36
1.3
1.5
—
—
—
0
0
169
1446
1.20
1.36
6.3
5.3
33.64
33.03
%
0.28
103
842
17
97
1.76
1.35
1.4
1.3
414561.00
101972.39
e6/l
—
10
61
20
120
1.68
1.34
1.2
1.4
—
—
—
0
0
5
18
2.79
1.28
1.2
1.2
—
—
—
0
0
106
871
1.24
1.28
1.5
1.6
1.50
1.62
%
1.43
80
741
29
420
0.68
1.23
1.9
1.8
3.62
3.43
mmol/l
0.43
24
313
44
589
0.74
1.19
2.4
2.1
3.68
3.50
ratio
0.42
38
480
14
237
0.59
1.19
1.1
1.2
3.57
3.74
mmol/l
0.45
14
224
10
50
2.01
1.16
2.2
2.3
—
—
—
0
0
7
30
2.34
1.12
1.0
1.2
—
—
—
0
0
7
31
2.27
1.10
1.4
1.4
—
—
—
0
0
18
112
1.62
1.09
1.1
1.0
—
—
—
0
0
20
129
1.56
1.06
1.4
1.4
—
—
—
0
0
7
33
2.13
1.05
1.3
1.5
—
—
—
0
0
7
33
2.13
1.05
1.3
1.5
—
—
—
0
0
18
276
0.65
1.04
1.1
1.3
638.06
594.91
mg/l
0.13
18
264
10
54
1.86
0.96
1.5
1.5
81.30
93.70
ng/l
—
10
54
155
1362
1.16
0.95
3.7
4.6
13.08
28.06
ug/l
0.90
127
1132
10
55
1.83
0.92
3.5
3.5
1.10
0.95
index
—
10
55
6
28
2.15
0.91
1.0
1.4
—
—
—
0
0
6
28
2.15
0.91
1.0
1.4
—
—
—
0
0
6
28
2.15
0.91
1.2
1.4
—
—
—
0
0
10
56
1.79
0.88
3.6
4.1
—
—
—
0
0
382
3572
1.11
0.86
5.3
4.9
21.78
21.57
%
0.11
207
1940
25
181
1.39
0.80
1.1
1.3
14.90
29.11
u/l
1.07
20
144
0
24
0.00
0.79
0.0
2.4
—
3.15
—
0
12
9
53
1.70
0.75
1.7
1.4
—
—
—
0
0
9
53
1.70
0.75
1.7
1.4
—
—
—
0
0
5
25
2.00
0.72
1.4
1.4
7.95
9.21
ug/l
—
5
25
5
25
2.00
0.72
1.4
1.0
406.26
327.72
iu/ml
—
5
25
27
203
1.34
0.71
1.1
1.2
—
—
—
0
0
7
42
1.67
0.68
1.0
1.0
—
—
—
0
0
33
260
1.28
0.64
1.1
1.1
—
—
—
0
0
12
79
1.52
0.62
1.2
1.1
0.16
1.17
u/ml
—
6
44
8
49
1.64
0.62
1.1
1.2
—
—
—
0
0
24
183
1.32
0.60
1.7
2.9
9.18
9.37
pmol/l
0.05
24
183
8
54
1.48
0.57
1.1
1.1
—
—
—
0
0
32
257
1.25
0.55
1.1
1.1
—
—
—
0
0
12
82
1.47
0.54
1.8
2.2
437.14
670.92
ml
—
7
53
6
38
1.58
0.54
5.7
2.9
219.50
192.18
u/l
—
6
38
9
60
1.50
0.54
1.7
1.3
—
—
—
0
0
18
238
0.75
0.53
5.8
3.3
28.16
29.76
mg/l
—
10
155
9
63
1.43
0.52
1.1
1.2
—
—
—
0
0
244
2292
1.08
0.50
5.2
4.1
1.02
1.02
kg/l
0.20
169
1527
7
46
1.52
0.48
4.7
1.5
36.51
40.23
g/l
—
7
46
11
76
1.45
0.48
1.6
1.5
—
—
—
0
0
14
102
1.38
0.47
1.9
1.1
4.00
2.84
u/ml
—
8
49
7
48
1.46
0.47
2.1
2.0
—
—
—
0
0
8
118
0.68
0.46
1.3
1.4
—
—
—
0
0
7
51
1.37
0.44
1.1
1.1
—
—
—
0
0
22
272
0.80
0.41
2.8
1.5
2.57
4.77
mg/l
1.29
16
206
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
14
105
1.34
0.41
1.9
1.1
2.25
1.52
u/ml
—
8
31
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.9
—
4.26
—
0
7
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
10
71
1.41
0.39
1.2
1.2
67.70
111.46
pmol/l
—
10
71
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
39
336
1.17
0.38
1.4
1.2
—
—
—
0
0
5
37
1.35
0.37
1.0
1.1
2412.80
1548.68
miu/ml
—
5
37
6
42
1.43
0.35
1.0
5.6
—
102.67
—
0
9
19
154
1.24
0.34
1.3
1.1
—
—
—
0
0
32
275
1.17
0.33
1.1
1.2
—
—
—
0
0
7
52
1.35
0.31
3.6
2.3
—
—
—
0
0
7
55
1.27
0.30
1.3
1.4
—
—
—
0
0
7
56
1.25
0.29
1.3
1.4
—
—
—
0
0
16
194
0.82
0.28
1.3
1.5
—
—
—
0
0
8
63
1.27
0.27
1.0
1.2
—
—
—
0
0
6
84
0.71
0.24
1.3
1.0
—
—
—
0
0
5
39
1.28
0.23
2.2
2.3
287.00
695.94
e6/l
—
5
31
32
285
1.13
0.23
2.9
3.4
11.94
1631.88
u/ml
1.08
27
263
5
40
1.25
0.22
3.2
2.4
126.60
261.24
e6/l
—
5
33
12
146
0.82
0.22
1.5
1.2
1.27
1.51
g/l
2.85
12
146
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
6
50
1.20
0.19
1.2
1.0
—
—
—
0
0
14
165
0.85
0.19
1.4
1.2
0.92
0.89
g/l
0.23
14
165
7
58
1.21
0.18
1.4
1.4
—
—
—
0
0
7
58
1.21
0.18
1.4
1.4
—
—
—
0
0
5
66
0.76
0.17
1.2
1.1
—
—
—
0
0
5
69
0.72
0.17
1.2
1.1
—
—
—
0
0
5
69
0.72
0.17
1.2
1.1
—
—
—
0
0
8
71
1.13
0.16
1.0
1.2
—
—
—
0
0
9
79
1.14
0.15
1.0
1.2
—
—
—
0
0
9
81
1.11
0.15
1.1
1.2
2.15
2.15
mmol/l
—
9
76
5
64
0.78
0.08
1.2
1.1
—
—
—
0
0
6
72
0.83
0.07
1.2
1.1
—
—
—
0
0
8
78
1.03
0.07
1.1
1.8
—
—
—
0
0
7
82
0.85
0.07
1.3
1.3
—
316.00
—
0
5
10
89
1.12
0.07
1.1
1.9
—
—
—
0
0
11
101
1.09
0.04
1.5
1.4
—
—
—
0
0
11
102
1.08
0.03
1.3
1.2
—
—
—
0
0
11
107
1.03
0.00
1.0
1.3
—
—
—
0
0
50
503
0.99
0.00
2.7
3.7
190.21
2933.74
u/ml
0.79
43
436
20
195
1.03
0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
93
0.97
-0.00
1.3
1.1
91.22
118.37
%
—
9
87
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
5.60
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
80
1.00
-0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
46.67
—
0
7
9
96
0.94
-0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
6.40
—
0
8
8
84
0.95
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.1
—
—
—
0
0
5
57
0.88
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint I9_E_DRONE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_E_DRONE | 0.927 [0.77, 1.11] | 0.406 |
| Birth year | 0.996 [0.99, 1.0] | 0.387 |
During the follow-up period (1.1.1998 — 31.12.2019), 235 out of 1798 females with I9_E_DRONE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_E_DRONE | 0.704 [0.59, 0.84] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.017 |
During the follow-up period (1.1.1998 — 31.12.2019), 219 out of 2019 males with I9_E_DRONE died.
Mortality risk
Mortality risk for people of age
years, who have I9_E_DRONE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.078% | 0.177% |
| 5 | 0.57% | 0.898% |
| 10 | 1.349% | 2.186% |
| 15 | 2.555% | 4.226% |
| 20 | 4.654% | 7.241% |
Relationships between endpoints
↥Index endpoint: I9_E_DRONE – Dronedarone medication
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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