Benign neoplasm: Liver

CD2_BENIGN_LIVER

liver neoplasm: A benign or malignant epithelial neoplasm that affects the liver parenchyma and intrahepatic bile ducts. Representative examples of benign epithelial neoplasms include hepatocellular adenoma and intrahepatic bile duct adenoma. Representative examples of malignant epithelial neoplasms include hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D13.4&
  • Hospital discharge: ICD-8 21150
  • Cause of death: ICD-10 D13.4&
  • Cause of death: ICD-8 21150

2 out of 7 registries used, show all original rules.

1017

4. Check minimum number of events

None

1017

5. Include endpoints

None

1017

6. Filter based on genotype QC (FinnGen only)

926

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D13
Name in latin
Neoplasma benignum hepatis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3928 2744 1154
Only index persons 3579 2565 1014
Unadjusted period prevalence (%)
Whole population 0.06 0.08 0.03
Only index persons 0.08 0.09 0.04
Median age at first event (years)
Whole population 51.46 48.25 58.77
Only index persons 50.04 46.94 57.87

-FinnGen-

Key figures

All Female Male
Number of individuals 926 690 236
Unadjusted period prevalence (%) 0.21 0.24 0.11
Median age at first event (years) 52.61 49.19 62.64

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
955
Matched controls
9550
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.4
ICD-10 Finland
Benign neoplasm: Liver
4503599627370496.0
307.7
943
*
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
57.1
307.7
224
51
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
28.4
280.7
198
87
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
19.7
171.8
139
82
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
37.2
135.5
85
25
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
17.4
133.8
114
74
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.1
83.9
210
504
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
15.5
64.4
57
39
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
43.6
485
2755
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
39.2
191
706
D18.0
ICD-10 Finland
Haemangioma, any site
6.9
38.7
61
93
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
37.9
271
1230
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
6.2
36.4
64
109
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
6.8
32.6
52
80
JN3AD
NOMESCO Finland
Abdominal CT examination
2.7
27.1
169
705
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.0
26.9
130
473
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
26.9
319
1774
K76.9
ICD-10 Finland
Liver disease, unspecified
8.0
23.5
32
41
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
4.7
22.9
54
120
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
18.0
21.4
33
19
UJF32
NOMESCO Finland
Coloscopy
2.1
20.8
264
1484
K76.89
ICD-10 Finland
Other specified diseases of liver
23.0
20.5
29
13
JJB71
NOMESCO Finland
Laparoscopic resection of liver
67.9
17.8
20
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.4
17.5
65
201
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
17.5
301
1864
A02BC02
ATC
pantoprazole; systemic
1.8
15.7
659
5265
K76.80
ICD-10 Finland
Hepatic cyst
12.0
15.1
27
23
N02AX02
ATC
tramadol; systemic, rectal
1.7
15.1
410
2884
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
15.3
14.9
24
16
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
14.7
257
1585
J01MA02
ATC
ciprofloxacin; systemic
1.7
14.6
362
2475
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
4.7
14.6
34
75
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
14.4
237
1433
R07.0
ICD-10 Finland
Pain in throat
2.5
13.9
96
416
JN4CD
NOMESCO Finland
Very extensive body CT
3.9
13.5
40
106
A02BC05
ATC
esomeprazole; systemic
1.7
13.5
397
2828
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
13.1
13.4
23
18
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
21.5
13.4
19
9
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.9
13.3
64
231
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
13.1
213
1280
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
12.7
128
651
21150
ICD-8 Finland
Benign neoplasm of other parts of digestive system, Hepatis
+∞
12.5
12
*
R06.0
ICD-10 Finland
Dyspnoea
1.7
12.4
265
1724
JJB50
NOMESCO Finland
Excision of segments V, VI, VII and VIII of liver
47.3
11.9
14
*
WX402
NOMESCO Finland
General anaesthesia
1.8
11.5
231
1472
A02BC01
ATC
omeprazole; systemic
1.7
11.5
260
1713
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
4.7
11.5
26
56
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
11.4
419
3122
R4110
NOMESCO Finland
Physiotherapy
1.7
11.0
260
1729
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
43.8
10.9
13
*
D06
ICPC
Abdominal pain localized other
2.1
10.8
103
512
A02BC03
ATC
lansoprazole; oral
1.7
10.8
265
1781
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.0
10.7
125
669
D01
ICPC
Abdominal pain/cramps general
1.9
10.7
141
787
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.0
10.6
47
162
JN3AE, ,
SPAT
2.7
10.6
58
225
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.3
10.4
78
351
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.3
10.4
38
117
H53.1
ICD-10 Finland
Subjective visual disturbances
2.3
10.3
78
353
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
13.3
10.2
17
13
Z3231
NOMESCO Finland
Registered nurse
1.7
10.0
251
1689
K30
ICD-10 Finland
Functional dyspepsia
1.9
10.0
132
736
B01AB05
ATC
enoxaparin; parenteral
1.6
9.9
280
1941
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
9.9
142
814
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
9.9
143
822
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.0
9.9
118
637
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
26.3
9.8
13
5
N02BE01
ATC
paracetamol; systemic, rectal
2.0
9.7
851
7701
J01DB01
ATC
cefalexin; oral
1.8
9.7
795
7047
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
9.6
192
1217
UKC02
NOMESCO Finland
Cystoscopy
1.9
9.5
124
689
130
Kela drug reimbursment
Malignant tumour
2.3
9.4
75
346
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
17.7
9.4
14
8
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
9.6
9.3
18
19
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
9.3
149
885
UJF30
NOMESCO Finland
Ileoscopy through colon
2.0
9.2
104
551
K86.2
ICD-10 Finland
Cyst of pancreas
7.1
9.1
21
30
B01AB04
ATC
dalteparin; parenteral
2.6
8.9
53
214
XKD00
NOMESCO Finland
Uroflowmetry
2.0
8.9
103
549
R52.9
ICD-10 Finland
Pain, unspecified
1.9
8.9
109
594
R42
ICD-10 Finland
Dizziness and giddiness
1.7
8.8
203
1333
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
10.8
8.8
16
15
JN1AE, ,
SPAT
2.5
8.6
55
230
Z71.8
ICD-10 Finland
Other specified counselling
1.5
8.6
350
2624
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
8.6
338
2517
J01MA12
ATC
levofloxacin; systemic
1.7
8.5
158
977
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
8.5
135
798
JJA21
NOMESCO Finland
Laparoscopic biopsy of liver
20.2
8.5
12
6
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
3.2
8.4
33
106
JKA20
NOMESCO Finland
Cholecystectomy
3.5
8.4
28
81
P01AB01
ATC
metronidazole; oral, rectal
1.5
8.4
401
3106
JAH00
NOMESCO Finland
Laparotomy
3.2
8.3
33
107
R05
ICPC
Cough
1.6
8.2
252
1771
R51.80
ICD-10 Finland
Headache
1.7
8.2
174
1117
M54
ICD-10 Finland
Dorsalgia
1.8
8.2
134
800
SPAT1360
SPAT
Extensive global examination
2.3
8.1
60
269
A04
ICPC
Weakness/tiredness general
1.7
8.1
152
944
M79.6
ICD-10 Finland
Pain in limb
1.5
7.9
425
3357
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
7.9
93
499
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.0
7.9
83
428
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
7.9
94
507
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
10.9
7.8
14
13
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
7.7
238
1672
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
7.6
350
2677
R30.0
ICD-10 Finland
Dysuria
2.4
7.6
49
207
Z3226
NOMESCO Finland
Physiotherapist
1.7
7.5
164
1059
D11
ICPC
Diarrhoea
1.8
7.4
129
782
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
7.4
121
720
N03AX16
ATC
[U] pregabalin
1.6
7.4
205
1404
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
7.3
215
1494
N06AX12
ATC
bupropion; oral
1.9
7.3
88
477
C08CA01
ATC
amlodipine; oral
1.5
7.2
288
2135
D13.9
ICD-10 Finland
Benign neoplasm: Ill-defined sites within the digestive system
30.3
7.2
9
*
JJB30
NOMESCO Finland
Excision of two segments of liver
20.2
7.1
10
5
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
7.1
310
2337
H66.9
ICD-10 Finland
Otitis media, unspecified
2.0
7.1
74
381
JAH01
NOMESCO Finland
Laparoscopy
2.2
7.0
55
253
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.1
7.0
68
341
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
7.0
100
573
JJB10
NOMESCO Finland
Atypcal resection of liver
13.9
6.9
11
8
D39.10
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary without histology
3.2
6.9
26
82
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
2.2
6.9
58
275
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
2.5
6.8
41
168
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
6.7
104
610
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
3.2
6.6
25
79
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
3.5
6.6
22
64
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.6
398
3183
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
6.6
77
413
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
6.5
101
592
R06AX27
ATC
desloratadine; oral
1.5
6.5
295
2235
N03AX12
ATC
[U] gabapentin; oral
1.6
6.5
146
948
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.7
6.5
115
701
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
6.5
291
2200
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
6.5
136
869
JN3GE
NOMESCO Finland
Intraoperative ultrasound examination of abdomen
70.3
6.4
7
*
M03BX02
ATC
tizanidine; oral
1.4
6.4
594
5115
A02BA02
ATC
ranitidine; systemic
1.6
6.4
157
1042
R01AD58
ATC
fluticasone, combinations; nasal
1.5
6.4
262
1947
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.3
531
4488
R00.2
ICD-10 Finland
Palpitations
1.8
6.3
87
493
XX9KE
NOMESCO Finland
Ultrasound examination with contrast
26.9
6.2
8
*
XJA00
NOMESCO Finland
Intraoperative abdominal ultrasonography
26.9
6.2
8
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
6.1
132
848
D07AC01
ATC
betamethasone; topical
1.4
6.1
323
2514
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
6.1
65
338
Z2221
NOMESCO Finland
Medical doctor
1.5
6.1
252
1874
N20.9
ICD-10 Finland
Urinary calculus, unspecified
3.2
6.0
23
73

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
193
271
8.67
135.36
2.4
3.5
21.04
1310.30
u/ml
1.33
174
239
313
732
5.87
133.57
2.7
4.5
2.69
14.54
ug/l
1.31
213
594
89
65
15.00
97.53
1.3
1.5
—
—
—
0
0
749
4332
4.38
83.65
7.5
6.4
10.60
10.77
umol/l
0.19
721
4135
107
141
8.42
77.85
2.0
3.9
117.10
2161.76
u/ml
0.63
99
134
283
970
3.73
69.02
4.0
2.6
4.99
6.61
umol/l
2.80
254
847
245
783
3.86
65.97
2.7
2.3
0.23
0.22
g/l
1.06
237
738
623
3549
3.17
63.13
5.8
4.8
36.45
36.30
g/l
0.29
595
3359
426
2070
2.91
55.75
5.9
3.8
96.30
93.51
%
1.45
417
2016
585
3460
2.78
50.92
13.0
11.4
1.24
1.18
inr
0.33
469
2859
864
6387
4.70
50.11
10.6
7.9
81.34
76.78
u/l
3.06
840
6083
462
2663
2.42
38.89
3.2
2.6
54.79
61.39
u/l
1.60
428
2483
97
248
4.24
34.60
1.5
1.2
52.50
92.67
titre
—
8
30
489
3007
2.28
34.01
4.4
3.3
31.71
30.37
u/l
0.26
473
2854
360
2068
2.19
28.25
3.0
2.2
—
—
—
0
0
660
4799
2.21
27.84
6.6
4.7
6.55
6.53
mmol/l
0.10
638
4484
157
633
2.77
26.93
7.9
7.4
7.63
9.05
mmol/l
1.57
150
611
179
792
2.55
25.40
3.1
2.5
32.70
39.52
u/l
0.93
147
669
433
2773
2.03
24.58
2.8
2.2
—
—
—
0
0
569
4030
2.02
24.10
3.1
2.7
—
—
estimate
—
0
0
205
1011
2.31
22.67
8.5
7.0
104.99
104.42
mmol/l
1.21
205
1011
330
1990
2.01
21.53
1.7
1.5
2.15
2.29
g/l
0.91
219
1277
752
6032
2.16
20.94
4.9
3.2
62.04
42.30
u/l
6.93
729
5746
650
4952
1.98
20.84
9.2
9.4
4.36
4.02
e9/l
3.16
558
4357
218
1149
2.16
20.28
3.1
2.4
22.63
23.21
%
0.30
208
1075
246
1360
2.09
20.20
3.1
2.4
13.90
13.79
umol/l
0.09
236
1264
233
1264
2.12
20.10
3.0
2.3
2.50
2.37
g/l
2.28
219
1173
503
3569
1.86
19.52
8.0
6.1
1.21
1.21
mmol/l
0.06
473
3303
547
4011
1.85
18.84
9.6
6.7
1.21
1.21
mmol/l
0.04
494
3471
356
2301
1.87
18.24
1.4
1.3
0.60
1.74
u/ml
3.30
95
644
588
4440
1.84
18.10
6.5
6.2
0.57
0.55
e9/l
0.89
501
3884
588
4448
1.84
17.90
6.5
6.2
0.04
0.04
e9/l
0.29
501
3893
412
2806
1.82
17.70
6.7
6.1
—
—
—
0
0
601
4599
1.83
17.38
6.7
6.5
0.18
0.18
e9/l
0.09
515
4080
219
1223
2.03
17.18
3.5
2.9
3.07
3.09
e6/l
0.01
101
560
592
4535
1.80
16.78
6.6
6.2
2.40
1.94
e9/l
0.63
516
4065
233
1344
1.97
16.61
1.6
1.4
621.82
520.27
titre
0.31
55
296
437
3083
1.77
16.26
4.7
3.7
36.97
85.10
e6/l
1.97
302
2081
548
4127
1.77
16.22
6.7
6.1
57.60
56.92
%
0.72
527
3961
691
5576
1.87
16.18
5.2
4.4
332.38
1852.23
e6/l
—
8
73
379
2569
1.79
16.15
3.8
3.1
45.42
84.77
e6/l
0.61
274
1939
139
669
2.26
15.93
1.4
1.4
—
—
—
0
0
229
1336
1.94
15.69
3.0
2.8
0.83
0.99
e6/l
0.37
109
671
549
4177
1.74
15.29
6.8
6.2
28.47
28.49
%
0.01
527
3997
137
674
2.21
14.84
8.3
7.8
1.28
1.25
mmol/l
0.11
137
662
219
1282
1.92
14.75
2.2
2.5
100.31
111.83
ug/g
0.30
178
1027
536
4075
1.72
14.75
6.9
6.3
8.28
8.59
%
1.79
511
3857
535
4069
1.72
14.66
6.8
6.2
2.63
2.80
%
1.12
510
3844
917
8331
3.53
14.64
20.0
14.2
23.35
21.44
mg/l
1.06
832
6833
917
8331
3.53
14.64
22.0
15.8
139.73
139.64
mmol/l
0.58
911
8182
329
2193
1.76
14.50
3.6
3.0
0.28
0.40
e6/l
0.61
220
1577
533
4059
1.71
14.46
6.9
6.3
0.67
0.68
%
0.15
508
3825
917
8343
3.49
14.35
22.2
16.0
3.93
3.94
mmol/l
1.13
910
8172
158
834
2.07
14.25
8.3
8.4
7.42
7.41
ph
0.14
76
463
156
821
2.08
14.18
8.4
8.4
0.47
0.83
mmol/l
0.62
134
680
206
1196
1.92
14.17
1.3
1.2
—
—
—
0
0
126
613
2.22
14.00
10.2
9.2
—
—
—
0
0
117
557
2.25
13.69
2.1
1.7
1.20
1.38
g/l
0.96
112
515
201
1197
1.86
12.65
1.5
1.6
—
—
—
0
0
142
753
2.04
12.58
1.4
1.2
—
—
—
0
0
468
3529
1.64
12.47
2.6
2.1
—
—
—
0
0
121
606
2.14
12.46
3.8
3.7
86.78
80.08
ng/l
0.31
103
548
305
2060
1.71
12.45
3.9
4.1
—
—
—
0
0
179
1034
1.90
12.37
6.9
5.4
1.03
1.02
mmol/l
0.11
164
962
171
973
1.92
12.36
1.4
1.3
—
—
—
0
0
303
2050
1.70
12.26
2.2
1.7
0.90
1.08
mg/l
0.75
241
1560
77
332
2.43
11.28
2.6
1.8
22.07
20.71
s
0.36
67
298
228
1462
1.73
11.05
3.6
3.6
1261.88
295.56
ng/l
0.48
159
1012
89
424
2.21
10.36
8.0
10.5
16.29
15.79
%
0.95
89
408
20
21
9.70
10.29
1.3
4.2
5.80
5.61
ug/l
0.04
20
21
211
1360
1.71
9.93
4.0
3.2
0.82
0.82
mmol/l
0.12
193
1294
385
2884
1.56
9.81
3.1
3.3
2.37
2.35
mmol/l
1.52
351
2638
297
2108
1.59
9.50
3.0
2.6
327.36
326.89
umol/l
0.03
270
1875
180
1126
1.74
9.39
1.4
1.3
—
—
—
0
0
186
1178
1.72
9.27
2.2
1.9
—
—
—
0
0
453
3580
1.50
8.68
2.3
2.0
100.64
97.25
pmol/l
0.76
261
1949
389
2980
1.52
8.65
3.5
3.4
26.90
54.55
ng/l
0.67
224
1882
309
2255
1.55
8.59
2.7
2.2
2.63
2.75
mg/l
0.43
266
1952
491
3986
1.48
8.00
3.2
2.5
72.88
76.25
nmol/l
2.11
453
3663
549
4588
1.46
7.50
4.2
3.1
105.70
100.09
ug/l
0.30
524
4340
458
3699
1.46
7.48
3.8
3.3
6.15
6.21
ph
0.58
246
2136
115
679
1.79
7.26
1.4
1.3
355.07
215.75
u/ml
0.25
106
634
58
269
2.23
7.24
1.5
1.4
271.21
296.28
ug/g
0.35
33
157
109
636
1.81
7.15
1.3
1.2
—
—
—
0
0
72
371
2.02
6.87
1.6
1.6
8.21
8.69
u/ml
0.07
14
85
554
4680
1.44
6.87
4.2
3.7
0.04
0.34
estimate
0.45
84
907
115
690
1.76
6.87
4.8
3.4
2.07
1.78
mmol/l
0.34
104
587
119
722
1.74
6.84
4.8
3.4
7.37
7.38
ph
1.29
64
406
768
6921
1.56
6.81
5.4
4.6
14.51
14.54
pmol/l
0.12
715
6454
50
224
2.30
6.79
1.1
1.2
—
—
—
0
0
130
814
1.69
6.66
3.7
2.6
1.82
1.82
%
0.01
116
723
548
4646
1.42
6.50
4.3
3.6
14.86
6.66
estimate
0.23
94
963
314
2420
1.44
6.30
5.4
4.0
7.40
7.40
ph
0.03
218
1702
324
2512
1.44
6.29
3.1
2.8
—
—
—
0
0
542
4601
1.41
6.29
4.2
3.6
0.00
0.00
estimate
0.50
91
947
242
1775
1.49
6.26
2.9
2.6
5.69
7.10
e6/l
0.97
217
1614
48
219
2.25
6.26
4.3
4.1
47.05
43.01
mg/l
0.11
42
188
278
2097
1.46
6.24
2.9
3.1
1219.36
1014.41
ng/l
0.33
234
1762
220
1586
1.50
6.19
2.9
2.6
2.45
2.43
mmol/l
1.12
201
1432
47
219
2.21
5.85
4.4
4.1
44.23
73.64
mg/l
0.53
42
188
100
606
1.73
5.77
4.3
2.7
67.49
72.08
e9/l
0.81
71
440
918
8757
2.25
5.75
16.3
11.4
28.95
25.30
u/l
7.04
907
8561
20
60
3.38
5.74
1.2
1.1
—
—
—
0
0
342
2712
1.41
5.74
3.7
3.3
7.61
7.65
mmol/l
0.05
306
2334
854
7968
1.68
5.72
6.7
5.6
1.75
1.82
mu/l
1.52
805
7497
325
2559
1.41
5.67
6.4
5.8
—
—
—
0
0
296
2307
1.41
5.43
1.9
1.6
19.75
20.57
nmol/l
0.50
259
1988
75
426
1.83
5.40
7.3
6.9
24.49
24.30
mmol/l
0.20
75
407
42
198
2.17
5.11
3.2
3.8
1.34
2.62
ratio
1.50
25
112
34
147
2.36
5.06
1.0
1.0
0.07
0.09
u/ml
0.14
13
47
68
384
1.83
5.00
2.0
1.9
—
—
—
0
0
45
222
2.08
4.89
1.1
1.1
1.64
2.73
u/ml
0.58
23
114
237
1806
1.42
4.87
1.7
1.7
—
—
—
0
0
204
1516
1.44
4.81
4.1
2.6
539.41
528.60
mosm/kgh2o
0.28
177
1331
307
2453
1.37
4.74
2.2
2.1
161.12
191.96
u/l
0.38
292
2334
53
281
1.94
4.73
1.5
1.2
—
—
—
0
0
40
192
2.13
4.67
1.1
1.1
1.57
4.58
u/ml
1.70
21
97
81
492
1.71
4.66
2.0
3.0
128.13
170.18
ng/l
0.64
75
447
59
328
1.85
4.58
1.5
1.5
—
9.73
—
0
7
307
2468
1.36
4.52
3.9
3.5
72.19
48.18
mg/l
0.67
214
1583
34
155
2.24
4.51
1.0
1.1
4.92
5.95
u/ml
0.12
15
64
38
183
2.12
4.42
1.1
1.1
0.19
0.89
u/ml
2.60
15
74
15
45
3.37
4.33
1.9
2.0
1.84
6.29
nmol/l
—
10
36
65
382
1.75
4.22
2.6
2.2
—
—
—
0
0
904
8666
1.81
4.19
17.2
12.7
—
—
—
0
0
308
2503
1.34
4.17
4.7
4.2
16.91
8.85
mg/mmol
1.06
217
1570
33
154
2.18
4.16
1.1
1.1
—
—
—
0
0
55
310
1.82
4.11
1.7
1.5
1.30
1.20
g/l
1.35
55
294
54
304
1.82
4.05
1.9
2.0
1.44
1.45
g/l
0.04
43
267
96
632
1.58
4.05
3.3
3.7
4.40
4.57
pmol/l
1.19
88
560
43
225
1.95
4.02
5.4
4.0
1.21
1.31
mmol/l
0.45
43
219
238
1869
1.36
4.01
1.4
1.3
24.83
29.90
iu/ml
0.33
62
561
115
792
1.51
3.97
1.4
1.5
—
—
—
0
0
86
555
1.60
3.95
2.1
2.3
8.05
6.38
ug/l
0.31
76
497
78
494
1.63
3.86
3.7
2.2
12.39
11.95
nmol/l
0.16
65
447
823
7746
1.45
3.85
7.2
5.8
39.15
38.54
mmol/mol
1.14
788
7344
32
154
2.12
3.76
1.1
1.1
—
—
—
0
0
153
1132
1.42
3.66
2.7
3.1
4.44
5.27
e9/l
0.73
129
1008
34
170
2.04
3.63
1.0
1.1
1.15
3.00
u/ml
1.49
17
83
164
1232
1.40
3.60
1.7
1.7
1135.00
1204.84
nmol/l
0.48
128
943
124
890
1.45
3.50
2.1
2.1
383.09
382.43
nmol/l
0.01
108
840
62
382
1.67
3.44
2.7
2.6
0.57
0.63
%
0.91
62
382
76
493
1.59
3.44
2.4
2.5
—
—
—
0
0
108
757
1.48
3.44
5.7
3.7
7.38
7.35
ph
2.41
79
549
136
997
1.42
3.42
1.8
1.6
—
—
—
0
0
68
430
1.63
3.41
2.2
2.1
0.10
0.01
estimate
0.43
21
139
16
59
2.74
3.33
2.3
3.1
628.33
1063.41
mg
0.74
16
59
31
155
2.03
3.33
1.6
1.2
2.20
5.22
u/ml
1.01
15
59
27
130
2.11
3.20
1.4
1.2
—
—
—
0
0
42
711
0.57
3.19
4.8
3.6
—
—
—
0
0
8
15
5.37
3.19
1.3
1.1
0.06
0.02
u/ml
—
8
15
32
165
1.97
3.17
3.6
2.4
7.67
7.93
pmol/l
0.10
32
165
35
187
1.90
3.14
1.1
1.1
0.31
1.54
u/ml
1.93
16
93
44
253
1.77
3.14
2.4
2.1
9.96
10.56
g/l
0.63
37
236
214
1711
1.32
3.14
1.4
1.3
15.60
12.29
u/ml
0.20
84
680
314
2645
1.28
3.10
1.5
1.6
—
—
—
0
0
247
2021
1.30
3.05
4.3
3.7
1.02
1.76
kg/l
0.50
173
1350
23
106
2.20
3.05
3.0
2.1
—
—
—
0
0
87
599
1.50
3.04
2.5
3.0
66.98
67.49
g/l
0.29
76
559
52
318
1.67
3.00
1.2
1.3
—
—
—
0
0
835
7953
1.40
2.96
5.5
4.7
5.90
5.82
mmol/l
1.12
791
7417
31
163
1.93
2.93
1.1
1.1
—
—
—
0
0
435
3829
1.25
2.92
11.6
10.6
0.00
0.00
e9/l
0.05
335
3164
89
624
1.47
2.85
2.3
2.4
12.04
19.80
au/ml
—
7
71
48
292
1.68
2.83
1.3
1.2
4.66
8.61
u/ml
—
10
48
108
787
1.42
2.83
2.0
2.0
0.04
0.03
estimate
0.06
27
166
47
291
1.65
2.62
1.3
1.2
1.57
2.67
u/ml
—
7
30
53
339
1.60
2.60
3.0
3.2
—
—
—
0
0
73
503
1.49
2.57
1.1
1.1
—
132.82
—
0
11
62
413
1.54
2.56
1.7
1.5
0.27
0.36
mg/l
0.90
34
179
32
179
1.82
2.54
1.7
1.4
—
—
—
0
0
100
736
1.40
2.49
1.5
1.3
25.78
26.12
iu/l
0.04
81
639
407
3601
1.23
2.49
2.0
1.9
1.45
1.33
mmol/l
2.00
359
3119
51
327
1.59
2.48
3.1
5.0
1.67
1.54
%
0.39
51
307
820
7836
1.33
2.43
4.7
4.0
1.39
1.25
mmol/l
6.44
772
7314
29
160
1.84
2.41
1.4
1.4
184.18
158.15
au/ml
0.82
11
44
62
420
1.51
2.38
1.5
1.9
9.06
8.77
iu/ml
0.02
12
96
70
489
1.47
2.32
1.2
1.2
—
—
—
0
0
9
28
3.23
2.31
3.4
2.8
0.61
0.61
mmol/l
—
9
28
13
53
2.47
2.28
5.0
7.7
0.65
361.25
ug/l
—
8
33
6
13
4.64
2.27
1.8
2.0
—
—
—
0
0
34
202
1.71
2.24
2.6
3.2
1.00
2.05
index
0.70
16
105
153
1225
1.30
2.21
1.5
1.5
—
—
—
0
0
928
9088
1.75
2.20
31.3
21.8
269.51
257.95
e9/l
5.02
914
8945
137
1082
1.31
2.19
1.5
1.4
—
—
—
0
0
928
9091
1.74
2.15
31.2
21.7
90.49
90.79
fl
1.27
923
9016
14
61
2.31
2.15
1.1
1.0
1.42
0.22
u/ml
—
6
22
928
9093
1.73
2.12
31.2
21.7
30.04
30.22
pg
2.51
923
9017
928
9093
1.73
2.12
31.3
21.8
4.50
4.49
e12/l
0.35
914
8928
856
8262
1.35
2.11
5.6
4.8
4.66
4.72
mmol/l
0.99
820
7818
928
9094
1.72
2.11
31.3
21.8
7.06
6.67
e9/l
6.47
915
8922
8
25
3.22
2.09
1.8
1.2
36.38
28.48
s
—
8
25
853
8233
1.34
2.07
5.5
4.7
1.45
1.50
mmol/l
2.64
805
7748
45
295
1.55
2.04
3.1
5.4
0.89
0.88
%
0.07
45
273
11
44
2.52
2.01
1.5
2.5
3853.91
664.11
u/ml
0.53
11
44
9
32
2.83
2.00
1.0
1.3
—
—
—
0
0
26
148
1.78
2.00
1.7
1.7
—
—
—
0
0
45
299
1.53
1.93
1.2
1.3
—
—
—
0
0
9
33
2.74
1.93
1.2
1.6
73.33
72.39
nmol/24h
—
9
33
15
71
2.13
1.93
2.1
2.7
—
—
—
0
0
74
544
1.39
1.90
1.8
2.1
4227.41
5646.56
u/l
0.22
23
227
38
245
1.57
1.87
3.3
2.7
—
—
—
0
0
16
79
2.04
1.86
1.3
1.1
—
—
—
0
0
115
909
1.30
1.84
1.5
1.4
—
—
—
0
0
13
59
2.22
1.84
1.1
1.1
0.28
0.45
u/ml
—
5
14
68
497
1.40
1.82
3.2
3.1
7.42
7.42
ph
0.10
54
414
21
117
1.81
1.75
1.2
1.3
0.50
0.58
nmol/l
0.86
21
110
6
18
3.35
1.75
1.8
2.7
—
—
—
0
0
34
218
1.58
1.73
3.6
6.4
1.30
1.20
mmol/l
0.27
34
192
5
13
3.86
1.71
1.8
4.6
—
—
—
0
0
17
89
1.93
1.70
1.5
1.3
—
—
—
0
0
69
512
1.37
1.70
3.3
3.1
5.12
5.12
kpa
0.02
63
497
69
512
1.37
1.70
1.1
1.1
—
—
—
0
0
29
180
1.63
1.68
1.3
1.3
215.54
252.68
u/ml
0.36
13
108
860
8350
1.30
1.66
6.4
5.4
2.70
2.78
mmol/l
1.94
816
7875
10
41
2.45
1.64
1.5
1.7
—
4533.33
—
0
6
41
279
1.49
1.62
1.7
1.9
4.29
2.53
ug/l
0.21
33
250
16
84
1.92
1.60
1.1
1.1
—
—
—
0
0
6
20
3.01
1.58
1.7
1.4
5.67
9.29
mmol/l
—
6
20
7
26
2.70
1.58
2.7
1.8
56.20
50.58
ug/l
—
7
26
29
184
1.59
1.56
1.3
1.4
3.05
2.60
ug/l
0.25
23
166
42
290
1.47
1.55
1.6
2.1
2.45
4.47
iu/l
2.01
16
123
20
115
1.75
1.53
1.6
1.3
—
—
—
0
0
282
2503
1.18
1.53
4.6
3.8
0.00
0.01
estimate
1.34
83
906
24
146
1.66
1.52
3.1
7.5
11.50
11.12
mmol/l
0.21
24
131
14
72
1.96
1.49
1.6
3.4
—
—
—
0
0
13
65
2.01
1.49
1.0
1.2
—
—
—
0
0
24
147
1.65
1.48
3.1
7.5
103.08
105.36
mmol/l
1.28
24
132
9
37
2.45
1.48
38.3
27.3
5.98
6.90
ug/l
—
9
30
18
102
1.78
1.45
1.1
1.2
0.18
0.37
nmol/l
0.48
12
71
50
364
1.39
1.41
1.2
1.3
—
—
—
0
0
44
313
1.43
1.41
5.8
3.4
25.22
25.26
mmol/l
0.02
44
301
386
3531
1.16
1.41
4.2
3.4
0.00
0.03
estimate
2.72
69
793
16
90
1.79
1.33
3.1
2.8
2.18
1.32
g/24h
—
9
57
19
113
1.70
1.32
1.5
1.6
—
—
—
0
0
17
98
1.75
1.31
3.9
5.2
10.80
48.71
u/ml
—
7
32
16
91
1.77
1.29
1.1
1.1
—
—
—
0
0
5
18
2.79
1.28
1.4
1.1
—
—
—
0
0
15
84
1.80
1.27
1.5
1.2
—
—
—
0
0
59
451
1.33
1.26
1.3
1.6
303.51
310.77
mu/l
0.06
51
412
6
25
2.41
1.24
1.0
1.2
—
—
—
0
0
116
969
1.22
1.22
3.6
3.1
0.81
0.72
ug/l
0.46
82
623
27
180
1.51
1.22
3.1
2.9
1.99
1.56
mmol/l
1.13
27
175
94
768
1.25
1.21
1.3
1.2
170.50
142.33
u/ml
0.18
30
322
15
86
1.76
1.19
1.7
1.5
—
—
—
0
0
49
370
1.34
1.15
2.1
1.8
—
—
—
0
0
41
301
1.38
1.14
1.2
1.2
11.95
10.62
u/l
0.23
27
241
39
284
1.39
1.14
3.9
3.4
446.11
301.41
mg/l
0.42
19
118
22
144
1.54
1.09
1.4
1.9
—
9.40
—
0
5
30
211
1.44
1.07
1.6
1.7
—
—
—
0
0
21
137
1.54
1.06
2.0
1.5
250.13
336.59
mu/l
1.80
16
116
7
34
2.07
1.03
2.3
1.8
—
—
—
0
0
33
239
1.39
1.01
1.2
1.2
—
—
—
0
0
29
207
1.41
0.97
1.5
1.3
27.72
26.18
u/l
0.09
22
173
31
226
1.38
0.93
1.2
1.4
0.23
0.37
nmol/l
1.72
20
184
9
52
1.74
0.92
1.1
1.3
—
—
—
0
0
13
78
1.68
0.92
1.5
1.4
1.55
1.47
nmol/l
0.08
13
70
6
28
2.15
0.91
2.8
3.3
—
—
—
0
0
15
94
1.61
0.91
1.3
1.1
—
—
—
0
0
24
168
1.44
0.90
3.0
2.3
69.97
112.91
ug/min
0.38
15
102
8
42
1.91
0.88
1.6
1.3
101.38
173.04
mmol/24h
—
8
42
6
30
2.01
0.87
1.2
2.3
41.43
42.24
g/l
—
6
30
338
3612
0.90
0.83
2.9
2.9
—
—
—
0
0
15
98
1.54
0.78
1.6
1.8
—
—
—
0
0
6
34
1.77
0.76
1.3
1.2
—
—
—
0
0
5
25
2.01
0.72
1.6
1.4
—
—
—
0
0
5
26
1.93
0.70
1.2
1.4
—
—
—
0
0
43
347
1.25
0.69
1.5
1.6
—
—
—
0
0
10
61
1.65
0.68
1.4
1.6
10.55
11.48
umol/l
—
10
55
14
94
1.50
0.67
1.5
1.6
19.16
26.03
ng/l
0.62
14
94
231
2140
1.10
0.65
3.5
4.6
—
—
—
0
0
82
711
1.17
0.64
3.9
4.5
0.38
0.69
%
1.20
28
203
49
406
1.22
0.63
1.0
1.1
—
—
—
0
0
12
79
1.53
0.62
1.3
1.2
—
—
—
0
0
17
121
1.41
0.62
1.5
1.5
—
—
—
0
0
17
121
1.41
0.62
1.5
1.5
—
—
—
0
0
17
121
1.41
0.62
1.5
1.5
—
—
—
0
0
17
121
1.41
0.62
1.5
1.5
—
—
—
0
0
14
96
1.47
0.61
1.9
1.6
—
—
—
0
0
10
152
0.65
0.61
3.4
3.5
3.99
4.17
e9/l
—
10
152
178
1632
1.11
0.61
6.4
5.3
2.61
2.41
ug/l
0.20
167
1462
14
197
0.71
0.59
3.0
3.3
57.21
57.38
%
0.02
14
197
229
2133
1.10
0.58
2.0
2.0
—
—
—
0
0
6
35
1.72
0.57
1.3
2.1
—
—
—
0
0
6
35
1.72
0.57
1.5
1.6
0.48
0.45
e9/l
—
6
35
59
685
0.85
0.55
1.5
1.6
1133.51
1002.97
mu/l
0.35
45
564
12
171
0.70
0.55
4.2
2.7
—
—
—
0
0
27
213
1.28
0.54
1.1
1.3
3.99
3.64
mmol/l
0.91
27
200
6
39
1.54
0.53
2.7
3.5
1.00
0.85
index
—
6
39
48
406
1.19
0.52
1.2
1.4
233.69
242.39
miu/ml
0.07
27
203
32
261
1.23
0.50
1.2
1.1
—
—
—
0
0
82
728
1.14
0.50
4.3
5.0
1.76
0.19
%
0.42
21
172
10
67
1.50
0.49
1.0
2.0
47.88
40.41
%
—
10
67
7
46
1.53
0.48
1.4
3.4
9.73
8.93
mmol/l
—
7
46
14
102
1.38
0.47
1.4
1.1
—
—
—
0
0
10
68
1.48
0.47
2.1
1.7
—
—
—
0
0
90
999
0.89
0.46
1.4
1.3
—
—
—
0
0
79
705
1.13
0.46
4.2
4.7
0.05
0.12
%
0.80
22
180
276
2625
1.07
0.43
3.8
3.0
0.00
0.11
estimate
0.95
74
777
19
149
1.28
0.42
1.4
1.4
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
36
305
1.19
0.41
2.2
2.0
—
—
—
0
0
11
79
1.40
0.41
1.3
1.1
92.64
111.68
pmol/l
0.89
11
79
0
18
0.00
0.40
0.0
1.1
—
0.02
—
0
18
10
71
1.41
0.39
1.1
1.0
—
—
—
0
0
179
1682
1.08
0.39
1.6
1.7
59355244.55
41394158.85
pmol/l
0.11
155
1435
50
438
1.15
0.39
1.5
1.6
—
—
—
0
0
18
142
1.27
0.38
3.7
3.0
8.81
7.60
mmol/l
0.62
18
137
9
66
1.37
0.38
1.3
1.2
—
—
—
0
0
23
190
1.22
0.35
1.5
1.6
—
—
—
0
0
6
44
1.37
0.34
1.5
3.6
17.23
17.15
%
—
6
44
25
209
1.20
0.34
1.6
1.5
5808.36
12526.73
e6/l
1.00
14
150
6
45
1.34
0.33
1.3
1.2
173.00
500.72
u/l
—
6
39
6
45
1.34
0.33
2.2
1.4
139.17
148.07
nmol/l
—
6
45
6
45
1.34
0.33
5.5
1.8
80.17
110.50
ng/l
—
6
45
14
109
1.29
0.33
1.4
1.3
—
—
—
0
0
46
408
1.13
0.32
1.5
1.6
—
—
—
0
0
49
437
1.13
0.31
1.6
1.6
—
—
—
0
0
68
619
1.11
0.31
1.8
1.8
—
—
—
0
0
7
53
1.32
0.31
1.0
1.1
1972.86
1640.68
miu/ml
—
7
53
49
441
1.12
0.28
1.6
1.6
—
—
—
0
0
17
141
1.21
0.26
1.2
1.2
—
—
—
0
0
38
425
0.89
0.26
1.2
1.1
1.52
1.58
g/l
1.01
38
425
9
72
1.25
0.25
1.0
1.1
—
—
—
0
0
118
1114
1.07
0.25
2.0
1.8
—
—
—
0
0
9
74
1.22
0.25
3.7
2.9
—
—
—
0
0
9
74
1.22
0.25
1.0
1.5
1.25
1.19
promille
—
9
58
9
76
1.19
0.24
1.3
1.4
8.84
6.48
ug/l
—
9
63
48
436
1.11
0.24
1.5
1.6
—
—
—
0
0
22
190
1.16
0.23
1.9
1.8
—
—
—
0
0
24
209
1.15
0.23
1.1
1.1
—
—
—
0
0
11
88
1.25
0.22
1.0
1.1
—
—
—
0
0
5
40
1.25
0.22
1.0
1.7
—
—
—
0
0
5
40
1.25
0.22
1.0
1.3
95.08
149.30
pmol/l
—
5
40
5
41
1.22
0.22
3.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
9.60
—
0
5
0
10
0.00
0.21
0.0
5.7
—
5.01
—
0
10
11
89
1.24
0.21
4.8
1.9
—
—
—
0
0
118
1123
1.06
0.21
2.0
1.9
3.47
3.33
ratio
0.58
88
854
16
136
1.18
0.20
1.6
1.3
57.09
66.32
mmol/l
0.32
11
120
16
136
1.18
0.20
1.1
1.1
—
77.55
—
0
29
79
745
1.07
0.19
4.2
4.6
0.77
1.10
%
0.27
22
221
74
699
1.06
0.17
2.1
2.2
6.27
6.10
ph
0.79
43
451
8
71
1.13
0.16
1.3
1.1
—
—
—
0
0
91
869
1.05
0.15
1.8
1.7
3.54
3.42
mmol/l
0.40
61
606
65
616
1.06
0.14
5.2
3.5
1.23
1.23
mmol/l
0.31
58
530
23
254
0.90
0.14
3.9
8.4
—
—
—
0
0
18
160
1.13
0.14
1.7
1.2
—
—
—
0
0
17
189
0.90
0.12
2.9
2.3
126.75
129.34
g/l
—
8
156
14
157
0.89
0.11
3.2
3.9
40.79
22.16
mg/l
—
9
105
29
308
0.94
0.08
1.4
1.5
—
—
—
0
0
6
58
1.03
0.08
2.5
1.3
—
—
—
0
0
10
88
1.14
0.08
1.5
2.4
31.50
32.63
pg
—
10
88
7
67
1.05
0.08
13.4
15.0
0.63
0.65
mmol/l
—
7
62
24
256
0.94
0.08
1.4
1.3
—
—
—
0
0
8
77
1.04
0.07
1.6
1.3
6.01
6.10
mmol/l
—
8
71
30
316
0.95
0.07
1.5
1.6
—
—
—
0
0
29
304
0.95
0.06
1.4
1.5
1.20
1.28
mm
0.38
21
213
39
404
0.96
0.05
1.4
1.5
67.56
61.18
ug/l
0.37
31
336
16
168
0.95
0.02
1.0
1.1
1.65
2.41
eliau/ml
—
8
79
11
104
1.06
0.01
2.8
2.4
—
—
—
0
0
10
104
0.96
0.00
1.0
1.1
—
—
—
0
0
128
1279
1.00
0.00
1.6
1.8
—
—
—
0
0
21
211
1.00
0.00
1.2
1.1
—
—
—
0
0
21
211
1.00
0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
317.67
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
41.33
—
0
9
16
160
1.00
-0.00
8.2
3.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
74
0.95
-0.00
3.6
2.5
1.19
1.20
mmol/l
—
7
74
7
75
0.93
-0.00
3.6
2.5
4.47
4.00
mmol/l
—
7
75
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
0.03
—
0
8
7
70
1.00
-0.00
2.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
0.44
—
0
5
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
6
65
0.92
-0.00
1.3
1.3
68.50
74.63
umol/l
—
6
65
10
100
1.00
-0.00
3.3
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
349.80
—
0
5
7
75
0.93
-0.00
3.6
2.5
107.57
105.95
mmol/l
—
7
75

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_LIVER and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_LIVER 1.688 [1.43, 2.0] < 0.001
Birth year 0.997 [0.99, 1.01] 0.509

During the follow-up period (1.1.1998 — 31.12.2019), 253 out of 2095 females with CD2_BENIGN_LIVER died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_LIVER 1.949 [1.56, 2.44] < 0.001
Birth year 0.991 [0.98, 1.0] 0.054

During the follow-up period (1.1.1998 — 31.12.2019), 245 out of 876 males with CD2_BENIGN_LIVER died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_LIVER.

N-year risk Females Males
1 0.149% 0.446%
5 0.979% 2.341%
10 2.673% 6.015%
15 5.274% 11.44%
20 9.294% 19.489%

Relationships between endpoints

Index endpoint: CD2_BENIGN_LIVER – Benign neoplasm: Liver

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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